JP2014002046A - Preparation for inspection of liquid sample - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a preparation for inspection of a liquid sample which allows easy and uniform accommodation of a sample regardless of its degree of viscosity and microscopic inspection thereof.SOLUTION: A preparation 1 for inspection of a liquid sample is composed of a substrate part 2 and a lid part 3, with the substrate part 2 being provided with a recessed part 2a for accommodating a sample at its bottom, while the lid part 3 is provided integrally on the substrate part 2 via a hinge part 3a and is capable of covering the recessed part 2a. The lid part 3 is provided with a cutout part 3b which becomes an opening for injection of the sample when the lid part 3 covers the recessed part 2a, with the depth of the recessed part 2a is such that the capillary phenomenon occurs between the lower surface of the lid part 3 and the bottom surface of the recessed part 2a in a state which the lid part 3 covers the recessed part 2a from above. In order to maintain a distance between the lower surface of the lid part 3 and the bottom surface of the recessed part 2a, spacers 4 are provided to the bottom surface of the recessed part 2a and/or the lower surface of the lid part 3.

Description

  The present invention relates to a preparation for inspecting a liquid sample such as a body fluid with an optical microscope, and in particular, even if a residual stress is generated in the lid and the lid is warped, the sample regardless of the level of viscosity. The present invention relates to a preparation for liquid sample inspection that can be easily accommodated and inspected.

When observing a liquid sample such as blood, tissue fluid, or urine with a microscope, conventionally, a few drops of the liquid sample are dropped on a rectangular glass plate called a slide glass and subjected to a predetermined treatment such as staining, and a cover glass is attached. A slide was created.
However, it is not easy to make a liquid sample to a certain thickness, so that preparation of a preparation requires considerable skill, and the liquid sample leaks between the slide glass and the cover glass to contaminate the fingers. There was also. Further, since both the slide glass and the cover glass are made of glass, there is a problem that they are heavy and easily broken.

  Light and hard to break slide glass and cover glass, plastic slide glass and cover glass are in close contact with each other through a small gap, and a partition seals the left and right of the gap (cell), and samples are injected before and after the gap. There has been proposed a slide (see Patent Document 1) provided with an opening and a vent. In this slide, if a liquid sample is dropped into the opening for sample injection, the sample is automatically drawn into the cell by capillary action and spreads, and the thickness of the sample becomes uniform, so that a preparation can be easily made.

  However, not only samples with low viscosity but also samples with high viscosity such as urine sediments are to be examined. Even if such a highly viscous sample is dropped on the opening of the slide described in Patent Document 1, the sample is not automatically sucked by capillary action.

The plastic slide glass and cover glass that can be used even for highly viscous samples consist of a substrate part (slide glass) and a cover part (cover glass) that are integrally provided via a hinge part. In some cases, the lid is openable and closable with respect to the substrate (see Patent Document 2).
However, when a plastic cover glass is used, if the cover glass is made thick in order to provide appropriate rigidity, the thick cover glass will be in the way, and the objective lens of the microscope cannot be brought close to the sample. Becomes difficult. In addition, the transparency of plastic is generally lower than that of glass, and the thicker the lid portion, the less light passes through the lid portion, which makes it more difficult to observe the sample.
On the other hand, if the cover glass is made thin, it will not be possible to maintain an appropriate rigidity, and the cover glass will be bent during sample adjustment or observation, resulting in poor workability.

  As a method for obtaining a thin and highly rigid cover glass, there is a method in which a rib is provided on the peripheral edge of the lid (see Patent Document 3). In Cited Document 3, a groove is provided around the concave portion for introducing the liquid sample, and this groove has two roles of accommodating an extra liquid sample and accommodating a rib. ing.

JP-A-4-214519 JP 2012-32589 A JP 2012-83190 A

  However, when a thin part such as a cover glass is made using plastic, the thin part is warped or undulated, and the liquid sample layer becomes thin or thick at this part. It may become uniform and interfere with sample observation. This is considered to be due to the influence of the residual stress generated in the molded body due to conditions such as the temperature difference between the front and back surfaces of the mold, the direction in which the resin flows, and the speed. Therefore, even if a rib is provided as in Patent Document 3, the problem cannot be solved if a residual stress is generated inside the rib. It seems that residual stress can be eliminated by controlling the mold temperature and resin flow almost completely, but it is extremely difficult to create such a mold, and the development cost of the mold increases. is there.

  In view of such circumstances, the present invention solves the above-mentioned problems of the prior art, and not only can suitably perform inspection regardless of the viscosity of the liquid sample, but also makes the thickness of the liquid sample constant regardless of the residual stress of the lid. An object of the present invention is to provide a preparation for liquid sample inspection that can be suitably inspected.

  In order to achieve the above object, a first feature of the present invention includes a substrate portion and a lid portion, and the substrate portion is provided with a concave portion for accommodating a sample, and the lid portion includes a hinge portion. And is provided integrally with the substrate portion, and can cover the concave portion, and the lid portion is a cut portion that becomes an opening for sample injection when the concave portion is covered with the lid portion. A notch is provided, and the depth of the concave portion is a depth at which capillary action occurs between the lower surface of the lid portion and the bottom surface of the concave portion in a state where the lid portion is covered on the concave portion. The preparation for a liquid sample test is characterized in that a spacer is provided on the bottom surface of the concave portion and / or the bottom surface of the lid portion to maintain a space between the bottom surface of the lid portion and the bottom surface of the concave portion. And

  The second feature of the present invention includes the preparation for liquid sample inspection described above, wherein the spacer is in the form of dots and / or lines.

  According to a third aspect of the present invention, the preparation for liquid sample inspection is characterized in that the spacers are regularly arranged.

The preparation for liquid sample inspection according to the present invention is provided with a notch portion serving as an opening for sample injection at the edge of the lid portion, and in a state where the lid portion is covered on the concave portion that is a sample storage portion. Since the gap between the bottom surface of the lid and the bottom surface of the recess is configured so that capillary action occurs, in the case of a sample with low viscosity, the lid is covered on the recess for sample injection. When the sample is dropped into the opening, the sample automatically spreads between the lid and the recess due to capillary action, and the sample is accommodated in the recess.
When the viscosity of the sample is high, the sample can be easily accommodated in the concave portion by lifting the lid.
Further, since the spacer is provided on the bottom surface of the concave portion and / or the lower surface of the lid portion, the thickness of the sample layer can be made uniform even when residual stress is generated inside the lid portion. The sample inspection can be suitably performed.

  By making the shape of the spacer dot-like and / or linear, the influence of the spacer on the sample observation can be minimized.

  If the spacers are regularly arranged, for example, when the number of red blood cells is visually counted, it can be used as a measure of measurement, and workability is improved.

FIG. 1A is a schematic view showing an embodiment of a preparation for liquid sample inspection of the present invention, FIG. 1B is a cross-sectional view taken along line AA in FIG. 1A, and FIG. It is B sectional drawing. FIG. 2A is a schematic view showing a state in which the lid portion is covered with the concave portion in FIG. 1, and FIG. FIG. 3 is a partially enlarged cross-sectional view of FIG. 1 in a state where the lid portion is covered with the concave portion. FIG. 4 shows an example of the arrangement of spacers, and (a) and (b) are plan views showing an example in which dot-like spacers are arranged in a lattice pattern (excluding the center) in the recess. c) is a plan view showing an example in which dot-like spacers and linear spacers are arranged. FIG. 5 is an enlarged cross-sectional view of a preparation in which a portion between the lid portion and the concave portion is tapered. FIG. 6 is a schematic view showing another embodiment of the preparation for liquid sample inspection of the present invention. FIG. 7 is a schematic view showing a state in which the lid portion is closed in the liquid sample inspection preparation of FIG.

  The liquid sample inspection preparation 1 of the present invention comprises a substrate portion 2 and a lid portion 3 as shown in FIGS. 1 to 3, and the substrate portion 2 is provided with a concave portion 2a for accommodating a sample. The lid portion 3 is provided integrally with the base plate portion 2 via the hinge portion 3a and can be covered with the concave portion 2a. The lid portion 3 includes the lid portion 3 and the concave portion. A notch 3b that becomes an opening for sample injection when covered with 2a is provided, and the depth of the concave portion 2a is such that the lid 3 is covered on the concave portion 2a. The depth at which capillary action occurs between the bottom surface of the portion 3 and the bottom surface of the concave portion 2a, and the bottom surface of the concave portion 2a and / or the bottom surface of the lid portion 3 (the bottom surface of the concave portion 2a in the illustrated example) In addition, a spacer 4 is provided for maintaining a space between the lower surface of the lid portion 3 and the bottom surface of the concave portion 2a.

As shown in FIG. 1, the preparation for liquid sample inspection 1 of the present invention comprises a substrate portion 2 and a lid portion 3. The lid portion 3 is connected to the substrate portion 2 via a hinge portion 3a.
The shape of the substrate part 2 is not particularly limited, but it is preferable to use a horizontally long rectangular shape like a slide glass that has been frequently used for microscope observation, since it can be set on a microscope in the same manner as in the past and the sample can be observed. The thickness is not particularly limited, but is preferably about 2 to 3 mm as in the case of a conventional slide glass.

  The substrate portion 2 is provided with a concave portion 2a for accommodating a sample, and the concave portion 2a is covered with the lid portion 3 as shown in FIG. The shape of the lid portion 3 and the concave portion 2a is not particularly limited as long as the concave portion 2a can be covered with the lid portion 3 except for an opening for sample injection which will be described later. Similarly, if a square shape with a side of about 15 to 20 mm is used, the appearance will be the same as when a normal slide glass and cover glass are used, so that the inspection can be performed in the same manner as before.

The hinge portion 3a in the present invention is a portion for allowing the lid portion 3 to be opened and closed on the concave portion 2a. Although the structure is not particularly limited, a preparation for specimen inspection is often handled as a disposable, so it is sufficient if it has a strength that can withstand opening and closing several times.
For example, when the lid portion 3 and the substrate portion 2 are formed, 1 to 3 V-shaped cuts (notches) are provided between the two portions, which can be used as the hinge portion 3a. If the substrate part 2 and the cover part 3 are connected by such a hinge part 3a, depending on the material, the cover part 3 will not break even if it is opened and closed as many times as required for the preparation (about 2 to 3 times). This structure can be manufactured at low cost. Moreover, it can replace with a notch (notch) and it can also be set as a hinge part by making between the cover part 3 and the board | substrate part 2 into thin film form.

  In the present invention, as shown in FIG. 3, if the concave portion 2 a is covered with the lid portion 3, a space surrounded by the concave portion 2 a and the lid portion 3 is generated, and this space (hereinafter referred to as the sample chamber 6). In some cases, the sample is injected and contained. The shape of the sample chamber 6 may be determined arbitrarily so that the sample can be easily observed according to the sample and the contents of the inspection, but is usually about 15 to 20 mm in length and width and about 0.03 to 0.5 mm in height. .

  The present invention is characterized in that a spacer 4 is provided for keeping the height of the sample chamber 6 (that is, the interval between the lower surface of the lid portion 3 and the bottom surface of the concave portion 2a) constant. The spacer 4 may project downward from the lid 3, project upward from the concave portion 2 a, or may use both downward and upward, but the lid 3 If the spacer 4 is provided on the side, it may interfere with the sample observation.

The spacer 4 is almost the same as the height of the sample chamber 6, and the shape thereof is not particularly limited as long as it is a shape that does not hinder sample observation. That is, the spacer 4 has a planar spread that hinders sample observation. Although it is not necessary to have a shape, specific examples include a dot shape and a linear shape. In the present invention, a dot shape is a shape that fits in a circle having a diameter of 30 μm or less, preferably 15 μm or less, and a linear shape is a shape that has a width of 30 μm or less, preferably 15 μm, and is elongated. . With such a shape, the spacer 4 hardly affects the sample observation.
However, when the spacer 4 is linear, the sample collects around the spacer 4 depending on the viscosity of the liquid sample, the extending direction of the spacer 4 with respect to the flow direction of the sample in the sample chamber 6, and the thickness of the sample layer. Is more likely to be non-uniform, and this non-uniformity may interfere with sample observation.

Even if the number of spacers 4 is only one, a certain degree of effect can be obtained. However, providing a plurality of spacers 4 has a higher effect of making the height of the sample chamber 6 constant. In the case where a plurality of spacers are provided, it is possible to arrange the spacers 4 at random. However, if the spacers 4 are regularly arranged, for example, the number of blood cells can be used as a guide when counting visually, so that workability is improved.
For example, as shown in FIG. 1A, if four dot-like spacers 4 are arranged between the center point of the concave portion 2a and the middle point of each side, a total of four concave portions 2a. Of the four regions (indicated by the one-dot chain line in the figure) formed by dividing the inside of the region with the spacer 4 as a guide, the total number can be predicted by counting only one region. The same applies to the case where the side lengths of the recesses 2a are arranged at the intersections of three lines (shown by the one-dot chain line in FIG. 4A) as shown in FIG. 4A.
As shown in the example shown in FIG. 4B, the lengths of the sides of the concave portion 2a are arranged in a grid pattern at intersections of lines (indicated by a one-dot chain line in FIG. 4B). In such a case, however, the central spacer 4 may be omitted for the convenience of observation.
Alternatively, the number of spacers 4 can be increased by arranging dot-like spacers 4 in a grid pattern at the intersections of the lines that divide the side length into 5 to 8 equal parts. Since it is possible to distinguish between already counted and uncounted ones based on the positional relationship, it is possible to prevent counting errors such as double counting and forgetting counting. However, if the number of spacers 4 is too large, sample observation may be hindered. Therefore, when a large number of dotted spacers are arranged, the upper limit is preferably about 50.

When the linear spacer 4 is provided, it is preferable not to disturb the flow of the liquid sample dripped into the sample injection opening 3b. As an arrangement for that, as shown in FIG. 4C, an arrangement in which a linear spacer is arranged at the center of the concave portion 2a can be exemplified.
In FIGS. 1A, 4A, 4B, and 4C, for convenience of drawing, the spacer 4 is shown much larger than the actual size.

In the present invention, the lid portion 3 is provided with a notch 3b serving as an opening for dropping the liquid sample into the sample chamber 6. More specifically, as shown in FIG. 2, if the concave portion 2a is covered with the lid portion 3 provided with the notch portion 3b as shown in FIG. 1, the notch portion 3b is formed as shown in FIG. When the sample is dropped into this opening for sample injection, the sample is injected and accommodated in the sample chamber 6 by capillary action between the lid 3 and the concave portion 2a.
The position of the cutout portion 3b is not particularly limited as long as it is a portion that overlaps the concave portion 2a when the lid portion 3 is put on the concave portion 2a, but the concave portion 2a does not interfere with sample observation with a microscope. It is preferable to provide the notch portion 3b at a position overlapping with the end portion. In the example shown in FIGS. 1 to 3, a notch 3b is provided on the hinge 3a side, and a part of the notch 3b is formed when the lid 3 is covered with the recess 2a. It is configured to overlap with the end of the recessed portion 2a to be an opening for sample injection.

  As described above, in the present invention, when a liquid sample is dropped into the sample injection opening 3b, the liquid sample is spread and accommodated in the sample chamber 6 by capillary action. Specifically, for example, by setting the distance between the lower surface of the lid 3 and the bottom surface of the concave portion 2a (that is, the height of the sample chamber 6) to about 0.2 to 0.5 mm, urine, blood, A liquid sample having a relatively low viscosity such as tissue fluid is automatically injected and stored in the sample chamber 6 by capillary action.

In the case of a liquid sample having a relatively high viscosity, capillary action does not occur even when the sample is dropped onto the opening 3b. However, since the intermolecular force between the liquid sample and the sample chamber 6 is working, a slight force is required. If the liquid sample is added, the liquid sample may spread in the sample chamber 6. In such a case, the gap between the recess 2a and the lid 3 is tapered from the sample injection opening 3b toward the center of the lid 3 with the lid 3 covering the recess 2a. (Referred to as FIG. 5 hereinafter), a sample is dropped from the opening 3b and the upper portion of the taper 6a is pushed downward, thereby forming a recess. The sample can be pushed into the entire portion 2a.
In order to form the tapered portion 6a, the periphery of the cutout portion 3b of the lid portion 3 and / or the recessed portion 2a of the substrate portion 2 may be formed in a slope shape. In FIG. 5, the inside of the vicinity of the notch 3b of the lid 3 is formed in a slope shape.

  For example, when the viscosity of the sample is extremely high, such as urine sediment, it may be difficult to inject and accommodate the sample in the sample chamber 6 even if the sample is pushed in as described above. In such a case, the lid 3 is lifted and the sample is directly stored in the concave portion 2a, and then the lid 3 is covered on the concave portion 2a. In this case, if necessary, the sample is spread thinly by pressing the sample from above the lid 3.

As a method for making the lid 3 easy to lift, for example, as shown in FIG. 1, a finger-hanging convex portion 3 c is provided at the tip portion of the lid portion 3, and the lid portion 3 is opened by placing a finger on this portion. A method for making it possible However, when the finger-hanging convex part 3c protrudes from the edge of the substrate part 2, there is a greater risk that the inspection part or the like will hit the finger-hanging convex part 3c during the inspection and the lid part 3 will open unexpectedly. If not, it is difficult to lift the lid 3 with a finger.
In order to avoid such inconvenience, a finger hooking convex portion 3c is provided and a finger insertion concave portion 2c is provided in the vicinity of the concave portion 2a at the edge of the substrate portion 2 as shown in FIG. In addition, it is preferable that the finger-hanging convex portion 3c protrudes in the finger insertion concave portion 2c but does not protrude within the outer shape of the substrate portion 2. In this way, it is possible to put a finger on the finger-hanging convex portion 3c, and the risk that the inspection instrument or the like hits the finger-hanging convex portion 3c and the lid portion 3 opens unexpectedly is reduced.

  Further, in the present invention, as shown in FIG. 6, a preparation 1 having no finger insertion recess 2 c and finger hooking projection 3 c can also be used. In this case, in order to easily lift the lid 3, Non-slip irregularities (not shown) can be provided on the edge.

  When the lid 3 is opened and closed as described above, the lid 3 needs to have a certain degree of rigidity, but the method for obtaining the rigidity is not particularly limited. In the embodiment shown in FIGS. 1 to 3 and the embodiment shown in FIG. 6, the rib 3d protrudes from the back surface side of the lid portion 3 to ensure rigidity. For this reason, even if the thickness of the lid portion 3 is reduced to about 0.1 to 0.3 mm, the lid portion 3 is not bent when the lid portion 3 is opened and closed, and the workability is good. Further, since the lid 3 can be made thinner, the objective lens of the microscope can be brought closer to the sample, and the reflected light from the sample is not blocked by the lid 3 having low transparency, so that the sample can be observed. It becomes easy.

In the above case, the shape of the rib 3d is preferably a shape that can give rigidity to the lid portion 3 and fit in the groove portion 2b. If the rib 3d is made solid, when the preparation 1 is made by injection molding or the like, the portion of the lid portion 3 where the resin covers the concave portion 2a (hereinafter sometimes referred to as the covering portion 3e). First, the resin flows to the rib 3d portion, and then the resin flows from the rib 3d side toward the covering portion 3e, so that the resin merges near the center of the covering portion 3e, and a weld line is formed at this merged portion. There is. Since this weld line may hinder the observation of the sample, it is preferable not to be in the covering portion 3e. However, the rib 3d has a U-shape (see FIG. 3) that protrudes inward from the surface side. By doing so, it is possible to prevent the weld line from being formed in the covering portion 3e.
That is, if the rib 3d is U-shaped, the resin is less likely to flow to the rib 3d side, and as a result, the resin first flows to the covering portion 3e side, and then the resin flows from the covering portion 3e to the rib 3d. The resin does not merge in the covering portion 3e, and the formation of a weld line in the covering portion 3e can be suppressed.
The U-shaped rib 3d can be easily contracted and deformed in the width direction of the rib 3d when an external force is applied. Therefore, even if the dimensional accuracy of the rib 3d and the groove 2b is slightly worse (for example, in the width direction of the rib 3d). Even if the dimension is slightly larger than the dimension in the width direction of the groove 2b), the rib 3d can be suitably fitted into the groove 2b. Therefore, since it is not necessary to pay much attention to dimensional accuracy when preparing the preparation 1, the mold can be manufactured at a low cost and the yield of the product is improved.

  In order to prevent the cover part 3 from opening unexpectedly, it is preferable to provide a locking structure 5. Although the specific structure is not particularly limited, for example, as shown in FIG. 3, the protrusion 5 a is provided inward from the tip of the finger-hanging projection 3 c of the lid 3, and the finger insertion recess of the substrate unit 2. A structure is provided in which protrusions 5b are provided from the inside to the outside of 2c and these protrusions 5a and 5b are engaged with each other. When the lid 3 is opened, the protrusions 5a and 5b can be easily disengaged by placing a finger on the finger-hanging convex portion 3c and bending it slightly upward.

  However, as in the example shown in FIGS. 1 and 2, if the lid portion 3 and the substrate portion 2 are locked only at the central portion of the edge of the lid portion 3, only the central portion of the edge of the lid portion 3 is the substrate portion. 2 may be in close contact with each other, and the edge of the lid 3 may be warped and floated. In order to avoid such an inconvenience, as shown in FIG. 6, the protrusion 5 a and the protrusion 5 b may be engaged with each other at substantially the full width of the edge of the lid portion 3.

When the rib 3d is provided in the present invention, as shown in FIG. 1, a groove 2b deeper than the recess 2a is provided around the recess 2a, and the rib 3d is fitted into the groove 2b. It is preferable to configure. In this way, the rib 3d does not get in the way when adjusting or observing the sample.
Further, if the depth of the groove 2b is made larger than the protruding height of the rib 3d, an extra sample that cannot enter the sample chamber 6 flows into the groove 2b, so that an extra sample leaks from the opening 3b for sample injection. Thus, the risk of contaminating the surface of the substrate portion 2 is reduced. In addition, since it is not necessary to worry about the leakage of the sample, it is possible to prevent a trouble that the amount of the dropped sample is too small and a sufficient sample is not injected into the sample chamber 6.

  When the groove portion 2b is provided, the groove portion 2b may be provided around the entire periphery of the concave portion 2a. However, as shown in FIG. 1, the groove portion 2b is provided in the vicinity of the notch 3b serving as an opening for sample injection. It is preferable to omit it. In this way, the problem that the sample flows into the groove 2b before the sample chamber 6 is filled with the sample can be prevented, so that even when the amount of the sample to be dropped is small, the inspection can be performed without any problem. Further, it is possible to prevent a trouble that the sample flows into the entire groove 2b first and bubbles remain in the center.

Moreover, in order to prevent a sample from flowing into the groove part 2b first, as shown in FIG. 1, the wall part 2d can also be provided inside the groove part 2b. In this way, the sample dripped into the opening is blocked by the wall 2d, and after the recess 2a is filled with the sample first, the excess sample overflows into the groove 2b. Is further prevented from becoming insufficient or bubbles remaining in the sample in the concave portion 2a.
The wall 2d may be provided on the entire inside of the groove 2b. However, as shown in FIG. 1, a part of the side facing the side where the opening for dropping the sample is provided, preferably a recess. If the wall portion 2d is not provided at the corner portion of the portion 2a, and the absence portion of the wall portion 2d is used as the air vent 2e, the trouble that air bubbles remain in the concave portion 2a is further effectively prevented.

By roughening the surface of the substrate portion 2 except for the concave portion 2, the concave portion 2 and other locations can be distinguished at a glance (not shown). Thereby, for example, it is possible to immediately determine whether or not the concave portion 2 is under the objective lens by simply looking into the microscope, and workability is improved.
Further, as shown in FIG. 1, only a part of the surface of the substrate part 2 is roughened, and if necessary, a recording part 2f for writing and printing the name and number of the subject can be used. This can prevent troubles such as mistaking the subject.

When providing a plurality of concave portions 2a, an identification symbol for distinguishing each concave portion 2a may be attached. The identification symbols that can be used are not particularly limited, and may be anything other than alphabets, such as hiragana, katakana, numerals, geometric patterns, etc., as long as they can distinguish the respective recessed portions 2a.
The place to which the identification symbol is attached is not particularly limited as long as each concave portion 2a can be distinguished, and the identification symbol may be attached to the finger-hanging convex portion 3c, or may be attached around each concave portion 2a. .
The method of attaching the identification symbol is not particularly limited, and for example, the identification symbol may be engraved on a mold for forming the preparation 1 of the present invention so that the identification symbol protrudes in a relief shape. An identification symbol may be printed after molding.

  The recording part and the identification symbol as described above can be provided on the lid part 3 as shown in FIG. However, when the recording unit 3g or the identification symbol 3h is provided on the lid 3, the recording unit 3g or the identification symbol 3h is provided at a position where it does not overlap the concave portion 2a so as not to disturb the sample observation. In this case, the recording unit 2f provided on the substrate unit 2 may be omitted, and a manufacturer name, a product name, or the like may be described.

  The material of the liquid sample inspection preparation 1 in the present invention is not particularly limited as long as it is a transparent polymer material, and can be selected from ordinary optical transparent resins. Specific examples thereof include polyolefins such as acrylic resin, polycarbonate, polystyrene, polyvinyl chloride, polypropylene, and polymethylpentene, cyclic polyolefin, polyester resins such as polyethylene terephthalate, polybutylene terephthalate, and polyethylene naphthalate, polyamide resins, poly An arylate, a polyimide, etc. can be mentioned, Among these, an acrylic resin, a polycarbonate, and cyclic polyolefin are especially preferable.

  As described above, according to the preparation for liquid sample inspection of the present invention, the sample can be easily and uniformly accommodated regardless of the viscosity of the liquid sample, so that the workability is good and the inspection can be performed with high accuracy.

DESCRIPTION OF SYMBOLS 1 Preparation for liquid sample inspection 2 Substrate part 2a Recessed part 2b Groove part 2c Finger insertion recessed part 2d Wall part 2e Air vent 2f Recording part 3 Lid part 3a Hinge part 3b Notch part (opening part for sample injection)
3c Finger-hanging convex part 3d Rib 3e Covering part 3f Peripheral part 3g Recording part 3h Identification symbol 4 Spacer 5 Locking structure 5a, 5b Projection 6 Sample chamber 6a Taper part

Claims (3)

It consists of a substrate part and a lid part,
The substrate portion is provided with a concave portion for accommodating a sample,
The lid portion is provided integrally with the substrate portion via a hinge portion, and can cover the concave portion.
The lid part is provided with a notch part that becomes an opening for sample injection when the concave part is covered with the lid part,
The depth of the concave portion is a depth at which capillary action occurs between the lower surface of the lid portion and the bottom surface of the concave portion, with the lid portion covered on the concave portion.
A preparation for liquid sample inspection, characterized in that a spacer is provided on the bottom surface of the concave portion and / or the lower surface of the lid portion to maintain a distance between the bottom surface of the lid portion and the bottom surface of the concave portion.   The preparation for liquid sample inspection according to claim 1, wherein the spacer is dot-like and / or linear.   The preparation for liquid sample inspection according to claim 1 or 2, wherein the spacers are regularly arranged.

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