JP2014057713A - Housing container for artificial bone granules and kit for filling artificial bone granules - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a flexible housing container for artificial bone granules and a kit for filling the artificial bone granules, capable of preventing contamination of the artificial bone granules, having excellent operability without the need of a sterilizing operation or the like, transferring the artificial bone granules from a target lesion without leakage corresponding to the artificial bone granules of various grain diameters, and transferring them without causing the problem of clogging with the artificial bone granules or the like during transferring.SOLUTION: The housing container for the artificial bone granules includes a sterilized inner container which seals and houses the artificial bone granules and functions as transfer means capable of transferring the artificial bone granules to a lesion when the sealing is released, and an outer container which houses the sterilized inner container.

Description

  The present invention relates to a container for artificial bone granules and a kit for filling artificial bone granules formed of a flexible material.

  Artificial bone containing calcium phosphate such as apatite, calcium sulfate, calcium carbonate and the like has an affinity for autologous bone and can be directly bonded to autologous bone. Therefore, its usefulness has been evaluated, and it has been clinically applied mainly in orthopedics, neurosurgery, plastic surgery, oral surgery and the like.

  The artificial bone has various shapes, and a granular artificial bone (hereinafter sometimes referred to as “artificial bone granule”) is usually packaged in a bottle or a bag-like container. When the artificial bone is transferred from the packaging container to the affected area, if the artificial bone is directly transferred from the packaging container to the affected area, there is a problem that the artificial bone leaks from a target site of the affected area. If an artificial bone granule leaks to an undesired site, bone must be removed if it is not removed, so removal work is necessary. A method for collecting the artificial bone granules one by one has been taken, which is very complicated.

  As a method for transferring an artificial bone from a packaging container to an affected area, a method in which a storage packaging container and an injector are integrated has been proposed (see Patent Documents 1 and 2). However, although these proposed injectors are suitable for artificial bones of the type used by mixing with physiological saline, they are not suitable for artificial bone granules that are not mixed with physiological saline.

  There is a method of using a funnel in order to transfer the artificial bone granule from the packaging container to the affected part so as not to leak from the target site of the affected part. However, in order to prevent contamination of the affected part and the artificial bone granule filled in the affected part, the funnel needs to be sterilized every time it is used, and is not only complicated, but also a sterilizable metal funnel is used. Therefore, there is a problem that it is hard and is heavy and difficult to handle, and the operability is very poor. In addition, a dedicated funnel for transferring the artificial bone granules is not provided, and the size of the funnel cannot be selected depending on the particle size of the artificial bone granules, and the existing funnel must be used forcibly. There is also a problem of not obtaining. Furthermore, since the funnel is hard and has a tubular portion extending from a conical apex, which is a main body portion, granular artificial bone granules are very easily clogged in the tubular portion. The artificial bone granules can only be transferred little by little, and it takes time. Once clogged, there is a problem that the artificial bone granules cannot be transferred unless the artificial bone granules transferred into the hard funnel are taken out again to create a gap. .

  Therefore, contamination of the artificial bone granule can be prevented, and sterilization operation is not required, it is excellent in operability, and the artificial bone granule is leaked from the target affected part corresponding to the artificial bone granule having various particle sizes. There is a strong need to provide flexible artificial bone granule storage containers and artificial bone granule filling kits that can be transported without causing problems such as clogging of artificial bone granules during transport. is the current situation.

JP-A-63-82657 JP-A-4-35661

  An object of the present invention is to solve the above-described problems and achieve the following objects. That is, the present invention can prevent contamination of the artificial bone granules, and does not require a sterilization operation, is excellent in operability, and is intended for artificial bone granules of various particle sizes. To provide a flexible artificial bone granule container and artificial bone granule filling kit that can be transported without leaking from the affected area and can be transported without causing problems such as clogging of the artificial bone granules during the transportation. With the goal.

In order to solve the above-mentioned problems, the present inventors have made extensive studies and as a result, obtained the following findings. That is, by making the container for storing the artificial bone granules into a flexible container that functions as a transfer means capable of transferring the artificial bone granules to the affected area, contamination of the artificial bone granules can be prevented, and sterilization operation, etc. Is unnecessary, has excellent operability, can be transferred without forcing the existing hard funnel, and without leaking the artificial bone granules from the target affected area in response to artificial bone granules of various particle sizes Thus, it was discovered that the artificial bone granules can be transferred without causing problems such as clogging in a hard funnel during the transfer, and the present invention has been completed.
This invention is based on the said knowledge by the present inventors, and the means for solving the said subject are as follows.

The container for artificial bone granules of the present invention is a sterilized inner container that functions as a transfer means capable of sealingly storing artificial bone granules and transferring the artificial bone granules to an affected area when the sealing is released. And an outer container for accommodating the sterilized inner container.
The container for artificial bone granule is a flexible sterilized inner container that accommodates the artificial bone granule functions as a transfer means as it is, so that the artificial bone granule is transferred to the affected area without clogging the transfer means, and Even if the artificial bone granule has any particle size, the artificial bone granule can be transferred without leaking from the target affected part. Further, since the sterilized inner container is used, a complicated process such as sterilization of the transfer means is not required, and the artificial bone granules are not contaminated. Furthermore, since the artificial bone granules are accommodated in a double-structured container comprising an outer container and a sterilized inner container, it is possible to efficiently prevent bacteria and the like from adhering to the artificial bone granules in the sterilized inner container. .

Further, the artificial bone granule filling kit of the present invention includes an artificial bone granule and a transfer means capable of sealingly containing the artificial bone granule and transferring the artificial bone granule to an affected area when the sealing is released. A sterilized inner container that functions as an outer container that houses the sterilized inner container.
In the artificial bone granule filling kit, since the flexible sterilized inner container containing the artificial bone granules functions as a transfer means as it is, the artificial bone granules are transferred to the affected area without clogging the transfer means, and Even if the artificial bone granule has any particle size, the artificial bone granule can be transferred without leaking from the target affected part. Further, since the sterilized inner container is used, a complicated process such as sterilization of the transfer means is not required, and the artificial bone granules are not contaminated. Furthermore, since the artificial bone granules are accommodated in a double-structured container comprising an outer container and a sterilized inner container, it is possible to efficiently prevent bacteria and the like from adhering to the artificial bone granules in the sterilized inner container. .

  According to the present invention, the conventional problems can be solved, the object can be achieved, contamination of the artificial bone granules can be prevented, sterilization operation and the like are unnecessary, and the operability is excellent. Flexible transferable without causing problems such as clogging of the artificial bone granule at the time of transfer. A container for artificial bone granules and a kit for filling artificial bone granules can be provided.

FIG. 1A is a top view seen from the first sheet side showing an example (1) of the first embodiment of the sterilized inner container in the container for artificial bone granules of the present invention. FIG. 1B is a top view seen from the first sheet side, showing a modified example (1-1) of the first embodiment of the sterilized inner container in the container for artificial bone granules of the present invention. FIG. 1C is a top view as seen from the first sheet side showing a modified example (1-2) of the first embodiment of the sterilized inner container in the container for artificial bone granules of the present invention. FIG. 1D is a top view seen from the first sheet side showing a modification (1-3) of the first embodiment of the sterilized inner container in the container for artificial bone granules of the present invention. FIG. 1E is a top view seen from the first sheet side showing a modification (1-4) of the first embodiment of the sterilized inner container in the container for artificial bone granules of the present invention. FIG. 1F is a top view seen from the first sheet side, showing a modified example (1-5) of the first embodiment of the sterilized inner container in the container for artificial bone granules of the present invention. FIG. 2 shows a further cut line for appropriately adjusting the maximum length of the opening in the example (1) of the first embodiment of the sterilized inner container in the container for artificial bone granules of the present invention. 1 is a top view as viewed from the sheet side of FIG. FIG. 3A shows an excision from an arbitrary point on one side A of the sterilized inner container of the container for artificial bone granules of the present invention along the direction of the other side B adjacent to the one side A. It is a figure which shows an example at the time of being carried out. FIG. 3B is an excision from an arbitrary point of the one side A along the other side B direction adjacent to the one side A in the arbitrarily selected one side A of the sterilized inner container in the container for artificial bone granules of the present invention. It is a figure which shows another example at the time of being carried out. FIG. 3C is a view of an arbitrary selected side A of the sterilized inner container in the container for artificial bone granules according to the present invention cut from an arbitrary point on the side A along the other side B adjacent to the side A. It is a figure which shows another example at the time of being carried out. FIG. 3D shows an excision from an arbitrary point on one side A of the sterilized inner container of the container for artificial bone granules according to the present invention along the direction of the other side B adjacent to the one side A. It is a figure which shows another example at the time of being carried out. FIG. 3E shows an excision along the direction of the other side B adjacent to the side A from an arbitrary point of the side A in an arbitrarily selected side A of the sterilized inner container in the container for artificial bone granules of the present invention. It is a figure which shows another example at the time of being carried out. FIG. 4A is an example of a relationship between an arbitrarily selected side A of the sterilized inner container in the container for artificial bone granules of the present invention, another side B adjacent to the side A, and their intersection [i]. FIG. FIG. 4B shows the relationship between the arbitrarily selected one side A of the sterilized inner container in the container for artificial bone granules of the present invention, the other one side B adjacent to the one side A, and the intersection [i]. It is a figure which shows an example. FIG. 4C shows the relationship between an arbitrarily selected side A of the sterilized inner container of the container for artificial bone granules of the present invention, another side B adjacent to the side A, and the intersection [i]. It is a figure which shows another example. FIG. 4D shows the relationship between the arbitrarily selected side A of the sterilized inner container of the container for artificial bone granules of the present invention, the other side B adjacent to the side A, and the intersection [i]. It is a figure which shows another example. FIG. 4E shows the relationship between an arbitrarily selected side A of the sterilized inner container of the container for artificial bone granules of the present invention, another side B adjacent to the side A, and the intersection [i]. It is a figure which shows another example. FIG. 4F shows the relationship between an arbitrarily selected side A of the sterilized inner container in the container for artificial bone granules of the present invention, another side B adjacent to the side A, and the intersection [i]. It is a figure which shows another example. FIG. 4G shows the relationship between the arbitrarily selected one side A of the sterilized inner container in the artificial bone granule storage container of the present invention, the other one side B adjacent to the one side A, and the intersection [i]. It is a figure which shows another example. FIG. 5A is a top view of the first sheet showing an example (2) of the second embodiment of the sterilized inner container in the container for artificial bone granules of the present invention. FIG. 5B is a top view of the first sheet showing a modification (2-1) of the second embodiment of the sterilized inner container in the container for artificial bone granules of the present invention. FIG. 5C is a side view showing an example of the transfer means of the aspect shown in FIG. 5A. FIG. 6A is a top view of the first sheet showing an example (3) of the second embodiment of the sterilized inner container in the container for artificial bone granules of the present invention. FIG. 6B is a top view of the first sheet showing a modified example (3-1) of the second embodiment of the sterilized inner container in the container for artificial bone granules of the present invention. FIG. 6C is a side view showing an example of the transfer means of the aspect shown in FIG. 6A. FIG. 7A is a top view of the first sheet showing an example (4) of the second embodiment of the sterilized inner container in the container for artificial bone granules of the present invention. FIG. 7B is a top view of the first sheet showing a modification (4-1) of the second embodiment of the sterilized inner container in the container for artificial bone granules of the present invention. FIG. 7C is a side view showing an example of the transfer means of the aspect shown in FIG. 7A. FIG. 8A is a top view of the first sheet showing an example (5) of the second embodiment of the sterilized inner container in the container for artificial bone granules of the present invention. FIG. 8B is a top view of the first sheet showing a modification (5-1) of the second embodiment of the sterilized inner container in the container for artificial bone granules of the present invention. FIG. 8C is a top view of the first sheet showing a modification (5-2) of the second embodiment of the sterilized inner container in the container for artificial bone granules of the present invention. FIG. 8D is a top view of the first sheet showing a modification (5-3) of the second embodiment of the sterilized inner container in the container for artificial bone granules of the present invention. FIG. 9 shows an appropriate adjustment of the size of the filling portion for filling the affected part with the artificial bone granule in the example (5) of the second embodiment of the sterilized inner container in the container for artificial bone granules of the present invention. FIG. 6 is a top view of a first sheet showing further tear lines for the purpose.

(Container for artificial bone granules, kit for filling artificial bone granules)
The container for artificial bone granules of the present invention is a sterilized inner container that functions as a transfer means capable of sealingly storing artificial bone granules and transferring the artificial bone granules to an affected area when the sealing is released. And at least an outer container that houses the sterilized inner container, and further includes other members as necessary.
The artificial bone granule filling kit of the present invention functions as a transfer means capable of sealingly containing the artificial bone granule and the artificial bone granule and transferring the artificial bone granule to the affected area when the sealing is released. A sterilized inner container and an outer container for accommodating the sterilized inner container, and further include other elements as necessary.
The artificial bone granule filling kit will be described below together with the description of the artificial bone granule container.

<Sterilized inner container>
The sterilized inner container is a container that functions as a transfer means for containing the artificial bone granule in a sealed manner and capable of transferring the artificial bone granule to the affected area when the sealing is released.

  In the present invention, the term “sealed” means a state in which the artificial bone granules housed in the sterilized inner container are closed without any gap from the sterilized inner container. The sterilized inner container may be in a vacuum state.

  The shape of the sterilized inner container is not particularly limited as long as the artificial bone granule can be sealed and accommodated, and can be appropriately selected according to the purpose. For example, a bag shape, a box shape, Examples include a bottle shape, a barrel shape, a columnar shape, and a ship shape. Among these, a bag shape is preferable in terms of easy handling, and a bag-shaped container including a first sheet and a second sheet is more preferable.

  There is no restriction | limiting in particular as a shape of the said bag-shaped sterilized inner container, According to the objective, it can select suitably, For example, square (for example, a regular square, a rectangle, trapezoid, a parallelogram etc.), circular ( For example, a perfect circle, an ellipse, etc.), a triangle (for example, a regular triangle, an isosceles triangle, a triangle in which each side has a different length, etc.) can be mentioned. Among these, quadrangle is preferable in terms of good production efficiency and easy handling.

  There is no restriction | limiting in particular as a magnitude | size of the said sterilized inner container, According to the quantity of the artificial bone granule to accommodate, a magnitude | size, etc., it can select suitably. In the case of a rectangular bag-like sterilized inner container, the average length × width is preferably about 120 mm × 70 mm to 200 mm × 150 mm, more preferably about 120 mm × 70 mm to 180 mm × 100 mm. If it is less than 120 mm × 70 mm, it may be difficult to form the transfer means, and a sufficient amount of artificial bone granules may not be accommodated. If it exceeds 180 mm x 100 mm, it takes a place for storage, and handling as a transfer means may deteriorate.

  The material of the sterilized inner container is not particularly limited and may be appropriately selected depending on the purpose, but is preferably a material that is not hard and can function flexibly as a transfer means, such as paper, nonwoven fabric, and synthetic resin. Etc. These may be used alone or in combination of two or more.

  There is no restriction | limiting in particular as a material of the said paper, According to the objective, it can select suitably, For example, a wood pulp, a synthetic pulp, these mixtures etc. are mentioned. As the paper, any of high-quality paper, art paper, coated paper, and recycled paper may be used.

  The nonwoven fabric may be manufactured by any of wet, dry, and direct manufacturing methods. Moreover, there is no restriction | limiting in particular as a material of the said nonwoven fabric, According to the objective, it can select suitably, For example, thermoplastic resins, such as polyethylene, a polypropylene, a polyethylene terephthalate, polyamide, these mixtures, etc. are mentioned. Furthermore, you may use the thing which consists of the fiber which coextruded these thermoplastic resins to the core-sheath structure, and the nonwoven fabric which joined the fibers of different materials. Among these, non-woven fabric made of polyethylene (for example, Tyvek (registered trademark), manufactured by Asahi DuPont Flashspun Products Co., Ltd., etc.) is preferable.

The basis weight of the paper or nonwoven fabric is not particularly limited and may be appropriately selected depending on the intended ^{purpose, 35g / m 2 ~100g / m} 2 is preferred. If the basis weight is less than 35 g / m ² , the strength may be insufficient, or formation of the transfer means may be difficult. If it exceeds 100 g / m ² , the cost may be disadvantageous, The material of the sterilized inner container itself becomes hard, and it may be difficult to form the transfer means.
There is no restriction | limiting in particular as the ventilation | gas_flowing amount of the said paper or a nonwoven fabric, According to the objective, it can select suitably.
There is no restriction | limiting in particular also as the air permeability of the said paper or a nonwoven fabric, Although it can select suitably according to the objective, 8 seconds-36 seconds are preferable. The air permeability can be measured by a method according to JIS P8117.

  There is no restriction | limiting in particular as a kind of the said synthetic resin, According to the objective, it can select suitably, For example, a polyethylene terephthalate (PET), a polytrimethylene terephthalate (PTT), a polybutylene terephthalate (PBT), a polyethylene naphthalate Polyester resins such as (PEN) and polybutylene naphthalate (PBN); polycarbonate (PC) resins; acrylic resins such as polymethyl methacrylate (PMMA); polyolefin resins such as polyethylene (PE) and polypropylene (PP); polyimide resins; Examples include triacetyl cellulose (TAC); polystyrene; nylon and the like. These may be used alone or in combination of two or more.

When the sterilized inner container has a bag shape, the container is preferably made of a film obtained by laminating PET and PE, a film obtained by laminating PET and PP, and the like. A film obtained by laminating PET and PE has low heat resistance and is suitable for sterilization with ethylene oxide gas. Moreover, the film which laminated PET and PP is especially suitable at the point with the high tolerance to an autoclave.
When the sterilized inner container has a box shape, a bottle shape, a barrel shape, a cylindrical shape, or the like, PP, PC, PE, polystyrene, or the like is preferable. The PP and PC are suitable because they are highly resistant to autoclaves. The PE is suitable because it is highly resistant to gamma sterilization.

  Among these, the sterilized inner container is formed by adhering a first sheet made of paper or a polyethylene nonwoven fabric and a second sheet made of a laminate of PET and PP. It is preferable in that it easily functions as a means.

  There is no restriction | limiting in particular as a method of closely_contact | adhering a said 1st sheet | seat and a said 2nd sheet | seat, According to the objective, it can select suitably, For example, the method of heat-sealing, the method of closely_contact | adhering with an adhesive agent etc. Can be mentioned. Among these, the heat sealing method is preferable because it is simple and has high safety without an adhesive or the like adhering to the artificial bone granule.

When the surfaces of the first sheet and the second sheet are not heat-sealable, a heat sealant can be applied to the first sheet and / or the second sheet.
There is no restriction | limiting in particular as a method of apply | coating the said heat seal agent, It can select suitably from well-known methods, For example, a gravure coat, a dip coat, etc. are mentioned.

<< Transportation means >>
The transfer means is means for transferring the artificial bone granules to the affected area. The transfer means functions when the sealed inner container is released.
Here, the release of the sealing means that at least a part of the space in which the artificial bone granules are accommodated is opened. The method for releasing the sealing is not particularly limited and may be appropriately selected depending on the purpose. For example, the sterilized inner container is cut by a known cutting means such as scissors, a cutter, and a scalpel or by hand. The method of doing is mentioned. Moreover, when the said sterilized inner container consists of a said 1st sheet | seat and a said 2nd sheet | seat, the method of peeling these sheets may be sufficient.

  The shape of the transfer means is not particularly limited and may be appropriately selected according to the purpose. However, any one of the funnel structure and the ridge structure corresponds to artificial bone granules having various particle sizes. Thus, the artificial bone granule can be transported without leaking from the target affected part, can be transported without causing problems such as clogging of the artificial bone granule at the time of transport, and is preferable in terms of being very flexible.

  The size of the transfer means is not particularly limited as long as the artificial bone granules can be transferred to the affected area, and can be appropriately selected according to the size of the affected area.

<Outer container>
The outer container is a container that houses the sterilized inner container. The artificial bone granule container has a double structure in which the sterilized inner container is accommodated in the outer container, thereby efficiently invading contaminants such as bacteria into the sterilized inner container during storage. Can be prevented. In addition, for the first time in a treatment room when transferring the artificial bone granule to the affected area, the artificial bone granule is contaminated when the artificial bone granule is transferred to the affected area by removing the sterilized inner container from the outer container. Can be prevented. The outer container is preferably sterilized.

  The shape of the outer container is not particularly limited as long as it is a shape that can accommodate the sterilized inner container, and can be appropriately selected according to the purpose. For example, a bag shape, a box shape, a bottle shape, a barrel , Circle, ship, etc. Among these, a bag shape is preferable in terms of easy handling.

  There is no restriction | limiting in particular as a shape of the said bag-shaped outer container, According to the objective, it can select suitably, For example, a square, a circle | round | yen, a triangle etc. are mentioned. Among these, quadrangle is preferable in terms of good production efficiency and easy handling.

  The size of the outer container is not particularly limited as long as it can accommodate the sterilized inner container, and can be appropriately selected according to the purpose.

  The material of the outer container is not particularly limited and may be appropriately selected depending on the intended purpose, but is preferably a material that does not allow contaminants to pass inside, and examples thereof include paper, nonwoven fabric, and synthetic resin. It is done. These materials can be the same as those used for the sterilized inner container.

  Hereinafter, one embodiment of the container for artificial bone granules will be described in detail with reference to the drawings. However, the container for artificial bone granules of the present invention is not limited thereto.

(First embodiment)
As a first embodiment, the sterilized inner container has an internal space in which the first sheet and the second sheet are brought into close contact with each other to accommodate the artificial bone granules, and an arbitrarily selected side A Is cut along the other side B direction adjacent to the one side A from an arbitrary point of the one side A, the maximum length of the cut opening is opposed to the opening in the internal space. The maximum length of at least one inner end is different.
The opening functions as a filling portion for filling the affected bone with artificial bone granules when the sterilized inner container functions as a transfer means.

<Example (1)>
A specific example (1) of the first embodiment is shown in FIG. 1A. FIG. 1A is a diagram illustrating a specific example (1) of the sterilized inner container according to the first embodiment, and is a top view of a first sheet.

The sterilized inner container of FIG. 1A has a quadrangular shape, and the first sheet and the second sheet are in close contact with each other at least from the first line to the fourth line shown in (I) to (IV) below. It is an aspect.
(I) Intersection [i-1] where one end of the arbitrarily selected one side A and one end of the other one side B adjacent to the one side A intersect, and one arbitrary point on one side D facing the other one side B A first line [1] connecting [m−1].
(II) An intersection [i-2] at which the other end of the other side B intersects with one end of the side C facing the side A, and an arbitrary point on the side D facing the other side B [m -2] is connected to the second line [2].
(III) Intersection [i-1] with the first line on the other side B adjacent to the one side A and the intersection [i-1] with the second line on the other one side B adjacent to the one side A -2] to the third line [3].
(IV) any one point [m−1] on one side D facing the other one side B (intersection with the first line [1] on one side D facing the other one side B); A fourth line connecting an arbitrary point [m−2] on one side D facing the other side B (intersection with the second line [2] on the one side D facing the other side B) [4].

  In FIG. 1A, a solid line represented by a bold line indicates at least a portion where the first sheet and the second sheet are in close contact with each other, but all of the outer periphery of the rectangular sterilized inner container, that is, the one side A, In the other side B, the side C facing the side A, and the side D (shown by a thin solid line in FIG. 1A) facing the other side B, the first sheet and the second sheet are in close contact with each other. May be.

  In FIG. 1A, any one point [m−1] on one side D facing the other side B and any one point [m−2] on one side D facing the other side B Although an embodiment in which they do not overlap has been shown, these may overlap. That is, in the example (1), the fourth line may not exist, and only the first line to the third line may be in close contact with each other.

  Further, in FIG. 1A, as indicated by a broken line in a region other than the internal space [Z], the first line [1] and the second line [2] are opposite to the internal space [Z]. In addition, it may have a tear line that cuts off a portion other than the internal space [Z]. By having such a tear line, it becomes easier to transfer the artificial bone granules to the affected area.

The position of the cut line is not particularly limited as long as it is formed in a portion other than the internal space [Z], and can be appropriately selected according to the purpose, but the first line [1] or the above It is preferable to be parallel to the second line [2].
The distance between the cut line and the first line [1] or the second line [2] is not particularly limited and may be appropriately selected depending on the purpose.

Further, in FIG. 1A, a fold line may be provided as indicated by a dotted line in the region of the internal space [Z]. By having such a fold line, the artificial bone granule can be suitably transferred to the affected area using the groove portion formed of the fold line as a ridge.
The position of the fold line is not particularly limited as long as it is within the area of the internal space [Z], and can be appropriately selected according to the purpose. However, it is preferably formed in the same direction as the one side A. In the third line and the fourth line, it is more preferable that a groove is formed at the center.

Further, as indicated by a broken line in FIG. 2, along the other side B direction adjacent to the side A from an arbitrary point on the side A, the maximum length of the opening can be adjusted to a desired length. May have a cut line [100] (hereinafter, may be referred to as "opening cut line [100]").
There is no restriction | limiting in particular as the number of the said cut-out lines [100] for openings, It can select suitably according to the objective.
Moreover, the numerical value which shows the maximum length of the said opening part may be described (printed) in the said sterilized inner container as description of the said cut-out line [100] for an opening part.

In Example (1), not only the opening but also at least one inner end facing the opening may be cut. When the artificial bone granules stored in the artificial bone granule container are insufficient by cutting the inner end portion, the artificial bone granules are preferably replenished from another artificial bone granule container. Can do.
Although not shown in the figure, the sterilized inner container may have one or a plurality of cut lines for cutting the inner end portion in this way.

  In the sterilized inner container, there is no particular limitation on the part where the cut line and the broken line shown in FIG. 1A and FIG. 2 are formed, and it can be appropriately selected according to the purpose. Preferably it is formed.

  Although the outer container is not shown in FIGS. 1A and 2, the artificial bone granule storage container of the present invention is such that these sterilized inner containers are stored in the outer container. That is, the artificial bone granules are accommodated in a double-structured container including an outer container and a sterilized inner container. This effectively prevents adhesion of germs and the like to the artificial bone granules in the sterilized inner container.

  In the example (1), the sterilized inner container in the artificial bone granule storage container is along the other side B direction adjacent to the side A from an arbitrary point of the side A in the arbitrarily selected side A. By being cut, a funnel structure is formed from the sterilized inner container, and this functions as a transfer means. Thereby, the artificial bone granule accommodated in the inside of the sterilized container can be used without being contaminated. Moreover, since the said transfer means consists of the said sterilized inner container, complicated processes, such as sterilization, are unnecessary.

When the sterilized inner container is cut, the maximum length of the excised opening is different from the maximum length of at least one inner end facing the opening.
In the case of the example (1), as shown in FIG. 3A, when cut at the broken line portion, the maximum length [o] of the opening portion is selected as the inner end portion facing the opening portion, that is, as described above. It is shorter than the maximum length [r] of the other side B adjacent to the one side A. The maximum length [o] of the opening of the sterilized inner container is adjusted by appropriately selecting an arbitrary point on the one side A, so that any artificial bone granule having any particle size can be used. The bone granules can be transferred without leaking from the target affected area. In addition, the amount of artificial bone granules to be transferred and the filling speed to the affected part can be appropriately adjusted.

  In the case of example (1), in the internal space [Z], the relationship between the maximum length [o] of the excised opening and the maximum length [r] of the other side B adjacent to the side A is [O] <[r], which is preferable in that the artificial bone granule is easily transferred to the affected area, but the maximum length [o] is different from the maximum length [r]. It is only necessary that the relationship is not limited to the above. Specific examples showing only the internal space [Z] are shown in FIGS. 3B to 3E. 3B to 3E, the broken line indicates the cut portion as in FIG. 3A. For example, in the case of FIG. 3E, the relationship between the maximum length [o] and the maximum length [r] is [r] <[o]. Such an aspect may be sufficient as the container for artificial bone granules of this invention.

The maximum length [o] of the opening is not particularly limited and can be appropriately selected according to the purpose, such as the size of the affected part, the size of the artificial bone granule, and the amount of the artificial bone granule to be transferred. 2 mm to 50 mm is preferable, and 5 mm to 20 mm is more preferable.
There is no restriction | limiting in particular also as maximum length [r] of the said inner side edge part, Although it can select suitably according to the objective, 20 mm-200 mm are preferable, and 30 mm-100 mm are more preferable.

  The opening in the transfer means functions as a filling part for filling the affected bone with the artificial bone granule, and the artificial bone granule accommodated in the sterilized container is transferred to the affected part. Since the transfer means is composed of the first sheet and the second sheet which are not hard, the transfer means is used flexibly, and the artificial bone granules are efficiently transferred to the affected area without clogging the transfer means.

  Further, in Example (1), when a broken line in a region other than the internal space [Z] shown in FIG. 1A is cut, unnecessary portions around the opening are removed. Thereby, even when the affected part is narrow, the artificial bone granule can be filled into the affected part without the transfer means coming into contact with the affected part.

  Further, when the dotted line in the area of the internal space [Z] shown in FIG. 1A is broken, a groove is formed. As a result, the artificial bone granules are more efficiently transferred to the affected area using the groove as a ridge.

<Modification (1-1)>
A modification (1-1) of the example (1) of the first embodiment is shown in FIG. 1B. FIG. 1B is a diagram illustrating a modified example (1-1) of the sterilized inner container according to the first embodiment, and is a top view of the first sheet.

The sterilized inner container of FIG. 1B has a quadrangular shape, and the first sheet and the second sheet are in close contact with each other at least from the first line to the fourth line shown in (I) to (IV) below. It is an aspect.
(I) Any one point [i-3] other than the end on the other side B adjacent to the arbitrarily selected side A and any one point on the side D opposite to the other side B [m− 1] is connected to the first line [1].
(II) A second point connecting any one point [i-4] other than the end portion on the other side B and any one point [m-2] on the side D opposite to the other side B. Line [2].
(III) Arbitrary one point [i-3] other than the end on the other side B adjacent to the one side A and Arbitrary one point [i-4] other than the end on the other side B A third line to connect [3].
(IV) any one point [m−1] on one side D facing the other one side B (intersection with the first line [1] on one side D facing the other one side B); A fourth line connecting an arbitrary point [m−2] on one side D facing the other side B (intersection with the second line [2] on the one side D facing the other side B) [4].

  In FIG. 1B, any one point [m−1] on one side D facing the other side B and any one point [m−2] on one side D facing the other side B Although an embodiment in which they do not overlap has been shown, these may overlap. That is, in the modified example (1-1), the fourth line may not exist, and only the first to third lines may be in close contact with each other.

  In the modified example (1-1), except that the first sheet and the second sheet are in close contact with at least the first line to the fourth line (I) to (IV) ( For example, the other contact portion between the first sheet and the second sheet, a cut line in a region other than the internal space [Z], a fold line in the region of the internal space [Z], and facing the opening. The aspect similar to that of the example (1) can be applied to all aspects of the cutting of the inner end of at least one of the inner containers and the outer container.

  The modified example (1-1) has substantially the same function as the example (1). However, in the modified example (1-1), as shown in FIG. 1B, compared to the example (1), In the internal space [Z], since the maximum length [r] (the length of the third line) of the inner end facing the opening is short, the transport means is in contact with the periphery of the affected part in a narrower affected part. The artificial bone granule can be filled into the affected area without any problem.

<Modification (1-2)>
A modification (1-2) of the example (1) of the first embodiment is shown in FIG. 1C. FIG. 1C is a view showing a sterilized inner container of the modified example (1-2) of the first embodiment, and is a top view of the first sheet.

The sterilized inner container of FIG. 1C has a quadrangular shape, and the first sheet and the second sheet are in close contact with each other at least from the first line to the sixth line shown in (I) to (VI) below. It is an aspect.
(I) Arbitrarily selected one point [n−1] other than the end on one side A and one arbitrary point [m−1] on one side D facing the other one side B adjacent to the one side A The first line connecting [1] and [1].
(II) Connect any one point [n−2] other than the end portion on one side C facing the one side A and any one point [m−2] on one side D facing the other one side B. Second line [2].
(III) Intersection where one end of the one side A intersects one end of the other one side B adjacent to the one side A (intersection with the first line [1] at the other one side B adjacent to the one side A) [ i-1] and an intersection at which the other end of the other side B intersects with one end of the one side C facing the one side A (intersection with the second line at the other one side B adjacent to the one side A) A third line [3] connecting [i-2].
(IV) any one point [m−1] on one side D facing the other one side B (intersection with the first line [1] on one side D facing the other one side B); A fourth line connecting an arbitrary point [m−2] on one side D facing the other side B (intersection with the second line [2] on the one side D facing the other side B) [4].
(V) a fifth point connecting an intersection [i−1] at which one end of the one side A and one end of the other one side B intersect with an arbitrary point [n−1] other than the end on the one side A Line [5].
(VI) An arbitrary point other than the intersection [i-2] where the other end of the other side B intersects with one end of the one side C facing the one side A and the end of the one side C facing the one side A A sixth line [6] connecting [n-2].

  In FIG. 1C, an arbitrary point [m−1] on one side D facing the other one side B and an arbitrary point [m−2] on one side D facing the other one side B Although an embodiment in which they do not overlap has been shown, these may overlap. That is, in the modified example (1-2), the fourth line may not exist, and only the first to sixth lines may be in close contact with each other.

  In the modification (1-2), except that the first sheet and the second sheet are in close contact with at least the first line to the sixth line shown in the above (I) to (VI) ( For example, other contact portions between the first sheet and the second sheet, a cut line in a region other than the internal space [Z], a fold line in the region of the internal space [Z], an outer container, etc.) The same aspect as that of Example (1) can be applied to all aspects.

  The modified example (1-2) has substantially the same operation as the example (1). However, the modified example (1-2) includes the fifth line and the sixth line, so that FIG. As shown in FIG. 4, the shape is closer to that of the existing funnel structure as compared with Example (1), and more artificial bone granules can be accommodated in the transfer means.

<Modification (1-3)>
A modification (1-3) of the first embodiment is shown in FIG. 1D. FIG. 1D is a diagram illustrating a modified example (1-3) of the sterilized inner container according to the first embodiment, and is a top view of the first sheet.

The sterilized inner container of FIG. 1D has a quadrangular shape, and the first sheet and the second sheet are in close contact with each other by at least first to third lines shown in (I) to (III) below. It is an aspect.
(I) An arbitrary point [i-3] on the other side B adjacent to the arbitrarily selected side A and an arbitrary point [m-1] on the side D facing the other side B The first line to connect [1].
(II) A second line [2] connecting any one point [i-4] on the other side B and any one point [m-2] on the side D facing the other side B .
(III) A third line [3] connecting any one point [i-3] on the other side B and any one point [i-4] on the other side B.
However, the first line [1] and the second line [2] intersect at an arbitrary point in the first sheet.

  In the modification (1-3), except that the first sheet and the second sheet are in close contact with at least the first line to the third line shown in (I) to (III) ( For example, other contact portions between the first sheet and the second sheet, a cut line in a region other than the internal space [Z], a fold line in the region of the internal space [Z], an outer container, etc.) The same aspect as that of Example (1) can be applied to all aspects.

  The modified example (1-3) has substantially the same operation as the example (1). However, in the modified example (1-3), as shown in FIG. 1D, compared to the example (1), Since the lengths of the first line and the second line are short and the transfer means is small as a whole, it can be applied to a small affected part and a finer work can be realized.

<Modification (1-4)>
A modified example (1-4) of the example (1) of the first embodiment is shown in FIG. 1E. FIG. 1E is a diagram illustrating a modified example (1-4) of the sterilized inner container according to the first embodiment, and is a top view of the first sheet.

The sterilized inner container of FIG. 1E has a quadrangular shape, and the first sheet and the second sheet are in close contact with each other at least from the first line to the fourth line shown in (I) to (IV) below. It is an aspect.
(I) An intersection [i−1] where one end of the arbitrarily selected one side A intersects one end of the other one side B adjacent to the one side A is connected to one end [m−1] of the other one side B. First line [1].
(II) Any point other than the intersection [i-2] where the other end of the other side B intersects with one end of the one side C facing the one side A, and an end portion of the one side D facing the other one side B A second line [2] connecting one point [m-2].
(III) Intersection [i-1] where one end of the one side A and one end of the other one side B intersect, and the intersection of the other end of the other one side B and one end of the one side C facing the one side A A third line [3] connecting [i-2].
(IV) One end [m−1] of one side D facing the other one side B (intersection with the first line [1] in one side D facing the other one side B) and the other one side A fourth point connecting any one point [m−2] (intersection with the second line [2] on one side D facing the other side B) other than the end portion on one side D facing B Line [4].

  In the modified example (1-4), except that the first sheet and the second sheet are in close contact with each other by at least the first line to the fourth line shown in (I) to (IV) ( For example, other contact portions between the first sheet and the second sheet, a cut line in a region other than the internal space [Z], a fold line in the region of the internal space [Z], an outer container, etc.) The same aspect as that of Example (1) can be applied to all aspects.

  In the modified example (1-4), as shown in FIG. 1E, the first line [1] and the one side A overlap each other. At this time, the second line [2] and the one side C facing the one side A do not overlap (an arbitrary point [m-2] other than the end portion on the one side D facing the other one side B) , And does not overlap with the other end of the side D opposite to the other side B).

  The modification (1-4) has substantially the same function as the example (1). However, in the modification (1-4), as shown in FIG. 1E, the first line and the fourth line Since the region sandwiched between the lines corresponds to the corner of the sterilized inner container, the corner can be used when the artificial bone granule is transferred to the affected area. Compared with the example (1), the length of the fold line indicated by the dotted line in the region of the internal space [Z] is longer as shown in FIG. 1E. The filling speed at which the granules are filled into the affected area can be adjusted efficiently.

<Modification (1-5)>
FIG. 1F shows a modification (1-5) of the example (1) of the first embodiment. FIG. 1F is a diagram illustrating a modified example (1-5) of the sterilized inner container according to the first embodiment, and is a top view of the first sheet.

The sterilized inner container of FIG. 1F has a quadrangular shape, and the first sheet and the second sheet are in close contact with each other at least from the first line to the fifth line shown in (I) to (V) below. It is an aspect.
(I) A first connecting an arbitrary one point [n−1] other than the end portion on the arbitrarily selected one side A and an arbitrary one point [m−1] on the one side D facing the other one side B. Line [1].
(II) Intersection [i-2] where the other end of the other side B and one end of the side C facing the side A intersect, and one end of the side D facing the other side B [m-2] A second line connecting the two [2].
(III) Intersection [i-1] where one end of the one side A and one end of the other one side B intersect, and the intersection of the other end of the other one side B and one end of the one side C facing the one side A A third line [3] connecting [i-2].
(IV) any one point [m−1] on one side D facing the other one side B (intersection with the first line [1] on one side D facing the other one side B); A fourth line [4] connecting one end [m-2] of one side D facing the other side B (intersection with the second line [2] on the one side D facing the other side B). .
(V) a fifth point connecting an intersection [i−1] at which one end of the one side A and one end of the other one side B intersect with an arbitrary point [n−1] other than the end on the one side A Line [5].

  In the modified example (1-5), except that the first sheet and the second sheet are in close contact with at least the first line to the fifth line (I) to (V) ( For example, other contact portions between the first sheet and the second sheet, a cut line in a region other than the internal space [Z], a fold line in the region of the internal space [Z], an outer container, etc.) The same aspect as that of Example (1) can be applied to all aspects.

  In the modified example (1-5), as illustrated in FIG. 1F, the second line [2] and the side C facing the side A overlap. At this time, the first line [1] and the one side A do not overlap (one arbitrary point [m−1] on one side D facing the other one side B and the other one side B) It does not overlap with the other end of side D).

  The modified example (1-5) has substantially the same function as the example (1). However, in the modified example (1-5), as shown in FIG. 1F, the second line and the fourth line Since the region sandwiched between the lines corresponds to the corner of the sterilized inner container, the corner can be used when the artificial bone granule is transferred to the affected area. Further, as compared with the example (1), the length of the folding line indicated by the dotted line in the region of the internal space [Z] is longer as shown in FIG. 1F. The filling speed at which the granules are filled into the affected area can be adjusted efficiently.

  Here, in the present invention, “one side” means one side of the sterilized inner container. In the specific examples and the modified examples, each side of the sterilized inner container is indicated by a straight line, but the shape of each side is not particularly limited and can be appropriately selected according to the purpose. It may be a curve, a broken line, or the like.

  In the present invention, “another side B adjacent to one side A” means a side adjacent to the one side A at a point (intersection) that intersects the one side A. Specific examples are shown in FIGS. 4A to 4G. 4A to 4G, [i] indicates an intersection.

  FIG. 4A is a diagram showing a case where each side of the sterilized inner container is a straight line and two straight lines intersect. In this case, the one side A and the other one side B cross each other at the intersection [i].

  FIG. 4B is a diagram showing a case where each side of the sterilized inner container is composed of a straight line and a constant curve, and one straight line and one constant curve intersect. In this case, when the straight line is the one side A, the other one side B, which is the curve, intersects at the intersection [i].

  FIG. 4C is a diagram showing a case where each side of the sterilized inner container is composed of an S-shaped curve that is continuous with a straight line, and one straight line and one continuous S-shaped curve intersect. In this case, the straight line is defined as the one side A, and an imaginary line [g1] composed of an extension line of the one side A is drawn. Next, in the continuous S-shaped curve, a virtual line [g2] composed of a tangent line that does not intersect any S-shaped curve is drawn. If the intersection of these virtual lines [g1] and [g2] is the intersection [i], the virtual line [g2] is the other side B.

  FIG. 4D is a diagram showing a case where each side of the sterilized inner container is formed of a continuous broken line and one straight line intersects with one continuous broken line. In this case, the straight line is defined as the one side A, and an imaginary line [g1] composed of an extension line of the one side A is drawn. Next, in the continuous broken line, a virtual line [g2] composed of a line connecting the convex portions that do not intersect any broken line is drawn. If the intersection of these virtual lines [g1] and [g2] is the intersection [i], the virtual line [g2] becomes the other side B.

  FIG. 4E is a diagram showing a case where each side of the sterilized inner container is formed of a continuous S-curve and two continuous S-curves intersect. In this case, in two consecutive S-shaped curves, a virtual line [g1] and a virtual line [g2] that are tangent lines that do not intersect any S-shaped curve are drawn. Assuming that the intersection of these virtual lines [g1] and [g2] is the intersection [i], one virtual line [g1] is the one side A and the other virtual line [g2] is the other one side B. It becomes.

  FIG. 4F is a diagram showing a case where each side of the sterilized inner container is composed of a continuous broken line and two continuous broken lines intersect. In this case, in two continuous broken lines, a virtual line [g1] and a virtual line [g2] composed of lines connecting the convex portions that do not intersect with any broken line are drawn. Assuming that the intersection of these virtual lines [g1] and [g2] is the intersection [i], one virtual line [g1] is the one side A and the other virtual line [g2] is the other one side B. It becomes.

  FIG. 4G is a diagram showing a case where each side of the sterilized inner container is composed of a continuous S-shaped curve and a continuous broken line, and one continuous S-shaped curve and one continuous folded line intersect. is there. In this case, first, in one continuous S-shaped curve, a virtual line [g1] composed of a tangent line that does not intersect any S-shaped curve is drawn. Next, in one continuous broken line, a virtual line [g2] composed of a line connecting convex portions that do not intersect any broken line is drawn. Assuming that the intersection of these virtual lines [g1] and [g2] is the intersection [i], one virtual line [g1] is the one side A and the other virtual line [g2] is the other one side B. It becomes.

  4C to 4G, the imaginary line [g1] and the imaginary line [g2] are drawn on the opposite side (outside the inner space [Z]) from the inner space [Z]. Even if an imaginary line is drawn inside [Z], there is no change in the other side B direction.

(Second Embodiment)
As a second embodiment, the sterilized inner container has an internal space in which the first sheet and the second sheet are in close contact to accommodate the artificial bone granules, and the first sheet has , Having a guide line, and when peeled from the second sheet and then folded or cut along the guide line, the artificial bone granule functions as a transfer means capable of transferring to the affected part.

  In the present invention, the guide line includes a cut line, a fold line, and the like. There is no restriction | limiting in particular as long as the effect of this invention is not impaired as a shape of the said guide line, According to the objective, it can select suitably, Not only a straight line but a curve, a broken line, etc. may be sufficient.

  In the second embodiment, the definitions of “one side” and “other side B adjacent to one side A” are the same as those in the first embodiment.

<Example (2)>
A specific example (2) of the second embodiment is shown in FIG. 5A. FIG. 5A is a diagram illustrating a specific example (2) of the first sheet in the sterilized inner container according to the second embodiment, and is a top view of the first sheet.

  In the example (2), the first sheet has a quadrangular shape, and includes a cut line made of a circle and a single cut line having a radius of the circle from the center of the circle toward the circumference. This is an embodiment having lines.

  In the first sheet [S], the guide line includes a cut line [7] composed of a circle and the circle from the center [Y] of the circle (a region surrounded by the cut line [7]) toward the circumference. And a cut line [8] having a length of a radius of.

  The position of the cut line [7] made of the circle is not particularly limited as long as it is within the first sheet [S], and can be appropriately selected according to the purpose. Further, the shape of the cut line [7] made of a circle may be not only a perfect circle but also an ellipse as long as it can function as a transfer means.

  There is no restriction | limiting in particular as a diameter of the cut line [7] which consists of said circles, Although it can select suitably according to the objective, 20 mm-200 mm are preferable, and 50 mm-100 mm are more preferable.

In Example (2), as shown in FIG. 5C, the cut line [7] and the cut line [8] are cut, and one end [8-1] cut by the cut line [8] When bonded along the radius of the circle cut at the cut line [7] along the radius of the circle, a funnel structure is formed, which functions as a transfer means. Thereby, the artificial bone granule accommodated in the inside of the sterilized container can be used without being contaminated. Further, the transfer means does not require complicated steps such as sterilization. Further, since the transfer means is composed of the first sheet that is not hard, it is used flexibly, and the artificial bone granules are efficiently transferred to the affected area without being clogged by the transfer means.
In the sterilized inner container, a bonding position for bonding the one end [8-1] may be indicated as a guide line.

  There is no restriction | limiting in particular as said means to adhere | attach, According to the objective, it can select suitably, For example, the method of using a well-known adhesive agent, the method of stopping with a staple etc., the method of stopping with an adhesive tape etc. are mentioned. Further, the joint portion may be simply pressed by hand without being fixed.

  The center [Y] of the circle functions as a filling portion for filling the affected part with the artificial bone granule, and the artificial bone granule is transferred to the affected part. By adjusting the bonding position of the one end [8-1], the opening diameter of the filling portion is appropriately adjusted. As a result, any artificial bone granule having any particle size can be transported without leaking from the target affected part. In addition, the amount of artificial bone granules to be transferred and the filling speed to the affected part can be appropriately adjusted.

  Further, the circumference of the cut line [7] functions as a transfer unit that transfers the artificial bone granule to the transfer means. In the example (2), when the artificial bone granules are insufficient due to having the transfer section, the artificial bone granules are suitably supplemented from within another artificial bone granule storage container.

<Modification (2-1)>
A modified example (2-1) of the example (2) of the second embodiment is shown in FIG. 5B. FIG. 5B is a diagram illustrating a modified example (2-1) of the first sheet in the sterilized inner container according to the second embodiment, and is a top view of the first sheet.

  In the modified example (2-1), as shown in FIG. 5B, the circle (region surrounded by the cut line [7]) is included in the cut line [7] made of the circle in the example (2). It further has a concentric cut line [9] having a smaller diameter. By having the cut line [9], the size of the filling portion [10] for filling the affected part with the artificial bone granule, the size of the affected part, the size of the artificial bone granule, the amount of the artificial bone granule to be filled, It can be appropriately adjusted according to the filling rate of the bone granules. Hereinafter, the cut line [9] may be referred to as “filling part cut line [9]”.

The number of the filling part cut lines [9] is not particularly limited and may be appropriately selected depending on the purpose.
There is no restriction | limiting in particular as a diameter of the said cutting part cutting line [9], Although it can select suitably according to the objective, 20 mm-150 mm are preferable, and 50 mm-100 mm are more preferable.
Moreover, when it has two or more said cutting part cutting lines (cutting line [9]), it is preferable that the space | interval of a diameter is 1 mm-10 mm.
Further, in the sterilized inner container, as an explanation of the filling part cut line (cut line [9]), the diameter of the filling part when the filling part cut line [9] is made to function as a transfer means is used. A numerical value (such as a diameter of the filling portion) indicated may be indicated (printed).

  The modified example (2-1) has substantially the same effect as the above example (2). However, in the modified example (2-1), as shown in FIG. Then, by cutting the filling part cut line [9] at a position selected as appropriate, the region indicated by the broken line in FIG. 5C is cut, thereby comparing the funnel structure with the above-mentioned example (2). , The opening diameter of the filling part [10] is more easily adjusted. As a result, any artificial bone granule having any particle size can be transported without leaking from the target affected part. In addition, the amount of artificial bone granules to be transferred and the filling speed to the affected part can be appropriately adjusted.

<Example (3)>
A specific example (3) of the second embodiment is shown in FIG. 6A. FIG. 6A is a diagram illustrating a specific example (3) of the first sheet in the sterilized inner container according to the second embodiment, and is a top view of the first sheet.

  As the example (3), the first sheet is formed along the other side B direction adjacent to the one side A from any one point other than the end portion on the one side A selected arbitrarily, and A first cut line having a length less than the length of the other side B and an arbitrary point other than the end of the other side B are formed along the direction of the side A, and the side A This is a mode having a guide line composed of a second cut line that does not intersect the first cut line.

  The guide line is formed along any one side B direction adjacent to the one side A from any one point [i-5] other than the end portion on the one side A that is arbitrarily selected in the first sheet [S]. Further, the one side A from the first cut line [11] having a length less than the length of the other one side B and any one point [i-6] other than the end portion on the other one side B. The second cut line [12] is formed along the direction and has a length less than the length of the one side A and does not intersect the first cut line.

The lengths of the first cut line [11] and the second cut line [12] are not particularly limited and may be appropriately selected depending on the purpose, but are preferably 5 mm to 50 mm, and preferably 10 mm to 30 mm is more preferable.
A plurality of the first cut lines [11] and the second cut lines [12] may be provided.

  When the sterilized inner container has a plurality of the first cut lines [11] and the second cut lines [12], any one of the first cut lines [11] is used. And any one of the second cut lines [12] is preferably cut.

  In Example (3), the first cut line [11] and the second cut line [12] are cut, and the end of the first cut line [11] opposite to the side A side By engaging [a] with the end [b] opposite to the other side B in the second cut line [12], an artificial bone granule as shown in FIG. 6C is affected. A funnel structure is formed which can be filled to the surface and functions as a transfer means. Thereby, the artificial bone granule accommodated in the inside of the sterilized inner container can be used without being contaminated. Further, the transfer means does not require complicated steps such as sterilization. Moreover, since the said transfer means consists of the said 1st sheet | seat which is not hard, it is used flexibly and this artificial bone granule is efficiently transferred to an affected part, without being blocked by this transfer means.

  After the end portion [a] and the end portion [b] are engaged with each other, an arbitrary region may be bonded as necessary to maintain and fix the engagement. There is no restriction | limiting in particular as a means of adhesion | attachment, According to the objective, it can select suitably, For example, the means etc. which were described in the said Example (2) are mentioned.

In the transfer means, the portion indicated by reference numeral [16] in FIG. 6C functions as a filling portion for filling the affected part with the artificial bone granule, and the artificial bone granule is transferred to the affected part.
The position of any one point [i-5] other than the end on the one side A and one point [i-6] other than the end on the other one side B, the first cut line [11], and The opening diameter of the filling portion [16] is adjusted by appropriately adjusting the length of the second cut line [12]. As a result, any artificial bone granule having any particle size can be transported without leaking from the target affected part. In addition, the amount of artificial bone granules to be transferred and the filling speed to the affected part can be appropriately adjusted.

<Modification (3-1)>
A modified example (3-1) of the example (3) of the second embodiment is shown in FIG. 6B. FIG. 6B is a diagram illustrating a modification (3-1) of the first sheet in the sterilized inner container according to the second embodiment, and is a top view of the first sheet.

In the modified example (3-1), as shown in FIG. 6B, in addition to the first cut line [11] and the second cut line [12] in the example (3), the cut line [ 13], cut line [14], fold line [15], and the like.
The cut line [13] is preferably formed from the end [a] toward an arbitrary point [i-7] on the side D facing the other side B. There is no restriction | limiting in particular as an angle which the said cut line [11] and the said cut line [13] make, It can select suitably according to the objective.
The cut line [14] is preferably formed from the end [b] toward an arbitrary point [i-8] on the side A. The angle formed by the cut line [12] and the cut line [14] is not particularly limited and may be appropriately selected depending on the purpose.

  The fold line [15] can be formed at an arbitrary angle with respect to the cut line [11] from an arbitrary position of the cut line [11]. The fold line [15] may be one or plural.

  The modification (3-1) has substantially the same operation as the example (3). However, in the modification (3-1), as shown in FIG. 6B, the cut line [13] and / or the By cutting the cut line [14], unnecessary portions of the transfer means are removed. Thereby, a transfer means can be formed more efficiently. In addition, since unnecessary gaps cannot be formed in the funnel-shaped transfer means, artificial bone granules can be efficiently filled into the affected area.

  Further, in the modified example (3-1), the folding line [15] is folded so that the end [a] and the end [b] are engaged with each other, and then the folding line [15] is folded. The transfer area can be formed without using the bonding means, and the region cut by the cut line [12] can be hooked.

<Example (4)>
A specific example (4) of the second embodiment is shown in FIG. 7A. FIG. 7A is a diagram illustrating a specific example (4) of the first sheet in the sterilized inner container according to the second embodiment, and is a top view of the first sheet.

  As the example (4), an arbitrary one point [i-9] other than an end portion on an arbitrarily selected side A of the first sheet [S] and an other side B adjacent to the one side A A fold line [17] composed of a line connecting any one point [i-10] other than the end, and each side of the first sheet [S] that is not parallel to the fold line [17] It is an aspect which has a guide line which consists of AD and the cut line [18] of arbitrary length which does not cross | intersect the fold line [17].

The lengths of the fold line [17] and the cut line [18] are not particularly limited and may be appropriately selected depending on the purpose. The length of the cut line [18] is the fold line. It is preferable that the length is equal to or greater than the length of [17] because the transfer means can be easily formed.
The number of the cut line [18] and the fold line [17] is not particularly limited and may be appropriately selected depending on the purpose.

  When the sterilized inner container has a plurality of the fold lines [17] and the cut lines [18], fold one of the fold lines [17] and the cut lines [18]. It is preferable that any one of these is cut | disconnected.

  In Example (4), after the cut line [18] is cut and the fold line [17] is folded, the fold line [17], the one side A, and another adjacent to the one side A By inserting the region [X] surrounded by the side B into the region cut by the cut line [18], a funnel structure as shown in FIG. Formed and this serves as a transfer means. Thereby, the artificial bone granule accommodated in the inside of the sterilized container can be used without being contaminated. Further, the transfer means does not require complicated steps such as sterilization. Moreover, since the said transfer means consists of the said 1st sheet | seat which is not hard, it is used flexibly and this artificial bone granule is efficiently transferred to an affected part, without being blocked by this transfer means.

  After the region [X] is inserted into the region cut by the cut line [18], the region [X] is adhered to an arbitrary position in order to maintain and fix the insertion portion as necessary. May be. There is no restriction | limiting in particular as a means of adhesion | attachment, According to the objective, it can select suitably, For example, the means etc. which were described in the said Example (2) are mentioned.

  In the transfer means, the portion indicated by reference numeral [19] in FIG. 7C functions as a filling portion for filling the affected part with the artificial bone granule, and the artificial bone granule is transferred to the affected part.

<Modification (4-1)>
FIG. 7B shows a modification (4-1) of the example (4) of the second embodiment. FIG. 7B is a diagram illustrating a modification (4-1) of the first sheet in the sterilized inner container according to the second embodiment, and is a top view of the first sheet.

  The modified example (4-1) is a mode in which the position of the cut line [18] in the example (4) is changed. As long as the cut line [18] is not parallel to the fold line [17] and does not intersect each side A to D of the first sheet [S] and the fold line [17], there is no particular limitation. For example, as shown in FIG. 7B, it may be formed at any position in the first sheet [S].

  The modified example (4-1) has substantially the same effect as the above-described example (4). However, in the modified example (4-1), the cutting site of the cut line [18] can be appropriately selected. The opening diameter of the filling part [19] can be adjusted. As a result, any artificial bone granule having any particle size can be transported without leaking from the target affected part. In addition, the amount of artificial bone granules to be transferred and the filling speed to the affected part can be appropriately adjusted.

<Example (5)>
A specific example (5) of the second embodiment is shown in FIG. 8A. FIG. 8A is a diagram illustrating a specific example (5) of the first sheet in the sterilized inner container according to the second embodiment, and is a top view of the first sheet.

As said example (5), it is an aspect which has a guide line which consists of the following 1st fold line and the following 2nd fold line.
[First folding line]
An intersection [i-11] where one end of the arbitrarily selected one side A and one end of the other one side B adjacent to the one side A intersect, and any one point on the one side D facing the other one side B [m− 3] is a first fold line [20].
[Second folding line]
An intersection [i-12] where the other end on the other side B and one end on the side C facing the side A intersect, and an arbitrary point [m-4] on the side D facing the other side B A second fold line connecting the lines [21].

  In FIG. 8A, an arbitrary point [m-3] on one side D facing the other side B and an arbitrary point [m-4] on the side D facing the other side B Shows an embodiment in which they do not overlap, but they may overlap.

In FIG. 8A, a cut line [22], a cut line [23], and the like are provided outside a region sandwiched between the first fold line [20] and the second fold line [21]. Also good. By having such a tear line, it becomes easier to transfer the artificial bone granules to the affected area.
As the position of the cut line [22] and the cut line [23], as long as it is formed outside the region sandwiched between the first fold line [20] and the second fold line [21], Although there is no restriction | limiting in particular, Although it can select suitably according to the objective, It is preferable that it is parallel to said 1st fold line [20] or said 2nd fold line [21].
The distance between the first fold line [20] and the cut line [22] or the distance between the second fold line [21] and the cut line [23] is not particularly limited. It can be appropriately selected depending on the case.

Further, a fold line [25] may be provided inside a region sandwiched between the first fold line [20] and the second fold line [21]. By having such a fold line, the artificial bone granule can be suitably transferred to the affected area using the groove portion formed of the fold line as a ridge.
The position of the fold line is not particularly limited as long as it is inside the region sandwiched between the first fold line [20] and the second fold line [21], and is appropriately selected according to the purpose. However, it is preferably formed in the same direction as the one side A, and is formed so that a groove is formed at the center between the first fold line [20] and the second fold line [21]. It is more preferable.

Furthermore, as shown by a broken line in FIG. 9, in order to appropriately adjust the size of the filling portion for filling the affected part with the artificial bone granule, another point adjacent to the one side A is selected from any point on the one side A. A cut line [200] (hereinafter, referred to as “filling part cut line [200]”) may be provided along the direction of one side B.
There is no restriction | limiting in particular as the number of the said cutting part cutting lines [200], According to the objective, it can select suitably.
Moreover, the numerical value which shows the length of the said filling part may be shown (printed) in the said sterilized inner container as description of the said cutting line for filling parts [200].

  In Example (5), although the outer container is not shown, the sterilized inner container is accommodated in the outer container of the container for artificial bone granules of the present invention. That is, the artificial bone granules are accommodated in a double-structured container including an outer container and a sterilized inner container. This effectively prevents adhesion of germs and the like to the artificial bone granules in the sterilized inner container.

In Example (5), the first sheet and the second sheet are peeled, and the peeled first sheet is divided into the first fold line [20] and the second fold line [ 21] is folded to form a cage structure, which functions as a transfer means. Thereby, the artificial bone granules can be used without being contaminated. Since the transfer means is composed of the first sheet, a complicated process such as sterilization is not required. Further, since the first sheet is not hard, it is used flexibly, and the artificial bone granules are used as the transfer means. It is efficiently transferred to the affected area without clogging.
When the first sheet and the second sheet are peeled, the artificial bone granules stored in the sterilized inner container are once transferred to another appropriately selected sterilized container at the time of application. Also good.

When the first fold line [20] and the second fold line [21] are folded, the first fold line [20] and the second fold line [21] on the first sheet. ], A distance between an arbitrary point [m-3] on one side D facing the other side B and an arbitrary point [m-4] on the side D facing the other side B The width of the filling portion for filling the artificial bone granule is adjusted, whereby any artificial bone granule having any particle size can be transported without leaking from the target affected area. In addition, the amount of artificial bone granules to be transferred and the filling speed to the affected part can be appropriately adjusted.
Moreover, the width | variety of the filling part filled with the artificial bone granule can be adjusted also by cut | disconnecting the cutting part cutting line [200] in the position selected suitably.

  Furthermore, in Example (5), when the cut line [22] and the cut line [23] shown in FIG. 8A are cut, unnecessary portions in the transfer means are removed. Thereby, even when the affected part is narrow, the artificial bone granule can be filled into the affected part without the transfer means coming into contact with the affected part.

  In Example (5), when the fold line [25] shown in FIG. 8A is folded, a groove is formed. As a result, the artificial bone granules are more efficiently transferred to the affected area using the groove as a ridge.

<Modification (5-1)>
FIG. 8B shows a modification (5-1) of the example (5) of the second embodiment. FIG. 8B is a diagram illustrating a modification (5-1) of the first sheet in the sterilized inner container according to the second embodiment, and is a top view of the first sheet.

The modified example (5-1) is an aspect having a guide line composed of the following first fold line and the following second fold line.
[First folding line]
Any one point [i-13] other than the edge in the other side B adjacent to the arbitrarily selected side A, and any one point [m-3] in the side D facing the other side B First fold line [20] connecting.
[Second folding line]
A second fold line connecting an arbitrary point [i-14] other than the end portion on the other side B and an arbitrary point [m-4] on the side D facing the other side B [ 21].

  In FIG. 8B, an arbitrary point [m−3] on one side D facing the other side B and an arbitrary point [m−4] on the side D facing the other side B Shows an embodiment in which they do not overlap, but they may overlap.

  In the modification example (5-1), except for having the first fold line [20] and the second fold line [21] (for example, the cut line [22], the cut line [23], the fold line [ 25], the cut-out line for filling part [200], the outer container, etc.) can be applied in the same manner as in Example (5).

  The modified example (5-1) has substantially the same effect as the above example (5). However, in the modified example (5-1), as shown in FIG. 8B, compared to the above example (5), Since the region sandwiched between the first fold line [20] and the second fold line [21] is narrow, in a narrower affected area, the artificial bone granule is transferred to the affected area without contacting the surrounding area of the affected area. Can be filled.

<Modification (5-2)>
FIG. 8C shows a modification (5-2) of the example (5) of the second embodiment. FIG. 8C is a diagram illustrating a modification (5-2) of the first sheet in the sterilized inner container according to the second embodiment, and is a top view of the first sheet.

The modified example (5-2) is a mode having a guide line composed of the following first fold line and the following second fold line.
[First folding line]
A first point [n-3] other than the end on the arbitrarily selected one side A is connected to one point [m-3] other than the end on the one side D opposite to the other one side B. 1 fold line [20].
[Second folding line]
An arbitrary point [n-4] other than the end on one side C facing the one side A and an arbitrary one point [m-4] other than the end on one side D facing the other one side B A second fold line to tie [21].

  In FIG. 8C, an arbitrary point [m−3] on one side D facing the other side B and an arbitrary point [m−4] on the side D facing the other side B Shows an embodiment in which they do not overlap, but they may overlap.

  In the modified example (5-2), except for having the first fold line [20] and the second fold line [21] (for example, the cut line [22], the cut line [23], the fold line [ 25], the cut-out line for filling part [200], the outer container, etc.) can be applied in the same manner as in Example (5).

  The modified example (5-2) has substantially the same operation as that of the example (5). However, in the modified example (5-2), as shown in FIG. 8C, compared to the example (5), Since the region sandwiched between the first fold line [20] and the second fold line [21] is wide, more artificial bone granules can be transferred at once.

<Modification (5-3)>
FIG. 8D shows a modified example (5-3) of the example (5) of the second embodiment. FIG. 8D is a diagram illustrating a modified example (5-3) of the first sheet in the sterilized inner container according to the second embodiment, and is a top view of the first sheet.

The modified example (5-3) is a mode having a guide line composed of the following first fold line and the following second fold line.
[First folding line]
A first connecting any one point [i-13] on the other side B adjacent to the arbitrarily selected side A and any one point [m-4] on the side D opposite to the other side B. Fold line [20].
[Second folding line]
A second fold line [21] connecting an arbitrary point [i-14] on the other side B and an arbitrary point [m-3] on the side D facing the other side B.

  In the modified example (5-3), other than having the first fold line [20] and the second fold line [21] (for example, the cut line [22], the cut line [23], the fold line [ 25], the cut-out line for filling part [200], the outer container, etc.) can be applied in the same manner as in Example (5).

  The modified example (5-3) has substantially the same operation as the example (5), but in the modified example (5-3), as shown in FIG. 8D, compared to the example (5), Since the region sandwiched between the first fold line [20] and the second fold line [21] is narrow and the transfer means is small as a whole, it can be applied to a small affected area, and finer work can be realized. .

  As mentioned above, although the specific example and the modification were given as the first embodiment and the second embodiment, it does not prevent having the cut line and the fold line other than the cut line and the fold line shown here. Absent.

  In the present invention, the cut line is not particularly limited and may be appropriately selected depending on the purpose. The cut part may be simply marked (for example, printed), and may be perforated. A cut may be made, but a perforated cut is preferred because it can be cut easily by hand. In the container for artificial bone granules, since the sterilized inner container is accommodated in the outer container, even if the sterilized inner container has a perforated cut, This is advantageous in that contaminants such as bacteria do not enter.

  In the present invention, the fold line is not particularly limited and may be appropriately selected depending on the purpose. The fold line may be only marked or may be folded in advance.

The guide lines (cut lines, fold lines, adhesion position index lines, etc.) and numbers are preferably printed on the first sheet.
In the case of printing, the printing surface is not particularly limited and can be appropriately selected depending on the purpose, but is preferably a surface that does not come into contact with the artificial bone granules.

<Artificial bone granules>
The material of the artificial bone granule is not particularly limited and can be appropriately selected from known materials according to the purpose. Examples thereof include calcium phosphates such as tricalcium phosphate and hydroxyapatite; calcium sulfate; calcium carbonate and the like. Can be mentioned.
The sterilized inner container may contain one type of these artificial bone granules, or two or more types.

  The shape of the artificial bone granule is not particularly limited and can be appropriately selected according to the purpose.For example, a block shape, a cube shape, a conical shape, a cylindrical shape, a quadrangular pyramid shape, a quadrangular prism shape, a button shape, Examples include a trapezoidal shape, a drum shape, a fan shape, and a shape obtained by appropriately combining these.

  There is no restriction | limiting in particular as a magnitude | size of the said artificial bone granule, According to the objective, it can select suitably. For example, those having an average particle diameter of 0.3 mm to 0.6 mm, 0.6 mm to 1.0 mm, 1.0 mm to 3.0 mm and the like can be mentioned.

  Commercially available products can be used as the artificial bone granule, and specific examples thereof include APACERAM (registered trademark), Bonfil (registered trademark), Superpore (registered trademark) (manufactured by HOYA Corporation), and the like. .

  There is no restriction | limiting in particular as the quantity of the artificial bone granule accommodated in the said container for artificial bone granules, It can select suitably according to the objective.

Examples of the aspect of the present invention include the following.
<1> a sterilized inner container that functions as a transfer means capable of containing the artificial bone granule in a sealed manner and transferring the artificial bone granule to the affected area when the sealing is released;
And an outer container for accommodating the sterilized inner container.
In the container for artificial bone granules described in <1>, since the flexible sterilized inner container for storing the artificial bone granules functions as a transfer means as it is, the artificial bone granules do not clog the transfer means. Even if the artificial bone granules are transferred to the affected area and have any particle size, the artificial bone granules can be transferred without leaking from the target affected area. Further, since the sterilized inner container is used, a complicated process such as sterilization of the transfer means is not required, and the artificial bone granules are not contaminated. Furthermore, since the artificial bone granules are accommodated in a double-structured container comprising an outer container and a sterilized inner container, it is possible to efficiently prevent bacteria and the like from adhering to the artificial bone granules in the sterilized inner container. .
<2> The artificial bone granule storage container according to <1>, wherein the sterilized inner container is a bag-shaped container including a first sheet and a second sheet.
In the container for artificial bone granules according to <2>, since the sterilized inner container is a bag-shaped container including a first sheet and a second sheet that are not rigid, the artificial bone granules are Even if the artificial bone granule is of any particle size, the artificial bone granule can be transferred without leaking from the target affected area without being clogged by the transfer means.
<3> The sterilized inner container has an internal space in which the first sheet and the second sheet are in close contact to accommodate the artificial bone granules,
When an arbitrary selected side A is cut from an arbitrary point on the side A along the other side B adjacent to the side A,
In the internal space, the artificial bone granule storage container according to <2>, wherein a maximum length of the excised opening is different from a maximum length of at least one inner end facing the opening.
In the artificial bone granule storage container according to <3>, the arbitrarily selected one side A is cut from an arbitrary point on the one side A along the other one side B adjacent to the one side A. As a result, an opening is formed. Thereby, the artificial bone granules accommodated in the sterilized inner container can be transferred from the opening to the affected part. At this time, in the internal space, the artificial bone granules are efficiently transferred to the affected area because the maximum length of the excised opening is different from the maximum length of at least one inner end facing the opening. Can do.
<4> The sterilized inner container is square,
The first sheet and the second sheet are
An intersection at which one end of the arbitrarily selected one side A and one end of the other one side B adjacent to the one side A intersect, any one point other than the end of the other one side B, and other than the end of the one side A A first line connecting any one point and any one point on one side D opposite to the other side B;
An intersection at which the other end of the other side B intersects with one end of the one side C facing the one side A, an arbitrary point other than an end at the other one side B, and an end at the one side C facing the one side A A second line connecting any one point other than the portion and any one point on one side D facing the other side B;
One of the points other than the intersection with the first line on the other side B adjacent to the side A and the end of the other side B, and the other side B adjacent to the side A A third line connecting any point other than the intersection with the second line and the end on the other side B;
A fourth line connecting the intersection of the first line on one side D facing the other side B and the intersection of the second line on the one side D facing the other side B;
A fifth line connecting an intersection of one end of the one side A and one end of the other one side B adjacent to the one side A and an intersection of the first line on the one side A;
Connecting the intersection of the other end of the other side B adjacent to the one side A and one end of the one side C facing the one side A to the intersection of the second line on the one side C facing the one side A The sixth line;
At least in close contact,
However, when either one of the first line and the second line overlaps one of the one side A and the other one side B, the first line and the second line The other line does not overlap any one of the one side A and the other one side B, and the maximum length of the third line and the maximum length of the fourth line are different from each other in <3>. This is a container for artificial bone granules.
In the container for artificial bone granules according to <4>, in the sterilized inner container, the first line, the second line, the third line, the fourth line, and the fifth line And the sixth line, the first sheet and the second sheet are brought into close contact with each other, thereby forming the internal space for accommodating the artificial bone granules. When the sterilized inner container is cut along the other side B direction adjacent to the side A from the arbitrary point of the side A in the arbitrarily selected side A, the maximum length of the cut opening The maximum length of at least one inner end facing the opening is different.
<5> The sterilized inner container has an internal space in which the first sheet and the second sheet are in close contact to accommodate the artificial bone granules,
When the first sheet has a guide line and is peeled off from the second sheet and then folded or cut along the guide line, the artificial bone granule can be transferred to the affected area. The container for artificial bone granules according to the above <2>, which functions as a transfer means.
In the artificial bone granule storage container described in <5>, when the first sheet and the second sheet are peeled, only the first sheet can function as the transfer means. Since the first sheet has the guide line, it can function as a transfer means efficiently by being folded or cut along the guide line.
<6> The artificial bone granule storage container according to <5>, wherein the first sheet has a quadrangular shape and has any of the following guide lines (i) to (iv).
(I) A guide line including a cut line made of a circle and one cut line having a radius of the circle from the center of the circle toward the circumference.
(Ii) The first sheet is formed along any other side B direction adjacent to the one side A from any one point other than the end portion on the one side A that is arbitrarily selected, and the other one side B It is formed along the one side A direction from any one point other than the first cut line having a length less than the length and an end portion in the other one side B, and less than the length of the one side A A guide line having a length and a second cut line that does not intersect the first cut line.
(Iii) From a line connecting any one point other than the end on the one side A arbitrarily selected on the first sheet and any one point other than the end on the other side B adjacent to the one side A And a cut line having an arbitrary length that is not parallel to the fold line and does not intersect each side of the first sheet and the fold line.
(Iv) An intersection at which one end of the arbitrarily selected one side A and one end of the other one side B adjacent to the one side A intersect, one arbitrary point other than the end of the other one side B, and an end of the one side A A first fold line connecting any one point other than the portion and any one point on one side D facing the other side B;
An intersection at which the other end of the other side B intersects with one end of the one side C facing the one side A, an arbitrary point other than an end at the other one side B, and an end at the one side C facing the one side A A guide line composed of any one point other than the portion and a second fold line connecting any one point on one side D opposite to the other side B.
In the container for artificial bone granules according to <6>, when the guide line of (i) is provided, the cut line formed of the circle and the length of the radius of the circle from the center of the circle toward the circumference A single cut line is cut off. Thereby, the area | region which consists of the said cut | disconnected circle | round | yen comes to be able to function as the said transfer means.
When the guide line of (ii) is provided, the first cut line and the second cut line are cut. Accordingly, the transfer means can function using the cut area.
In the case of having the (iii) guide line, the fold line is folded and the cut line is cut. As a result, the transfer means can function using the folded area and the cut area.
When the guide line (iv) is provided, the first fold line and the second fold line are folded. Thus, the transfer means can function using the folded area.
<7> The container for artificial bone granules according to <6>, wherein the guide line of (i) further includes a concentric cut line having a diameter smaller than the circle in the cut line made of a circle.
In the container for artificial bone granules according to the above <7>, by excising a concentric cut line having a diameter smaller than the circle, the artificial bone granules can be filled into the affected part from the excised part, Thereby, the filling amount, filling speed, etc. to the affected part of the artificial bone granule are adjusted. Moreover, since the said cut line is concentric, it can respond | correspond to the magnitude | size of various artificial bone granules by selecting the position to cut.
<8> The artificial bone granule storage container according to any one of <2> to <7>, wherein the first sheet is one of paper and polyethylene nonwoven fabric.
In the container for artificial bone granules described in <8>, the first sheet is one of paper and polyethylene non-woven fabric and is not hard, and thus functions as a flexible transfer unit. The bone granules are transferred to the affected area without clogging the transfer means, and the artificial bone granules of any particle size can be transferred without leaking from the target affected area.
<9> The artificial bone granule storage container according to any one of <1> to <8>, wherein the transfer means is any one of a funnel structure and a cage structure.
In the container for artificial bone granules according to <9>, since the transfer means is either a funnel structure or a cage structure, the artificial bone granules are efficiently leaked from the target affected part. Can be transferred to the affected area.
<10> The transfer device according to any one of <3> to <4>, wherein the transfer unit is a funnel structure including an internal space in which the first sheet and the second sheet are in close contact to accommodate the artificial bone granule. This is a container for artificial bone granules.
In the artificial bone granule storage container described in <10>, the transfer means is a funnel structure that can function as a funnel with the opening portion on the affected part side, whereby the container is stored in the sterilized inner container. The artificial bone granules can be transported without leaking from the target affected area.
<11> The transfer means is
In the case of having the guide line of (i), the cut line is cut, and one end cut by one cut line having a length of the radius of the circle is bonded to an arbitrary position of the circle along the radius of the circle A funnel structure
In the case of having the guide line (ii), the cut line is cut, the end of the first cut line opposite to the side A, and the other side B adjacent to the side A in the second cut line A funnel structure formed by meshing the end opposite to the side,
If (iii) has a guide line, the cut line is cut, the fold line is broken,
A funnel structure formed by inserting a region surrounded by the fold line, one side A, and another side B adjacent to the one side A into a region cut by the cut line,
When the guide line (iv) is provided, any one of the items <6> to <7>, wherein the fold structure is formed by folding a fold line made of the first line and a fold line made of the second line. A container for artificial bone granules according to claim 1.
In the artificial bone granule storage container according to <11>, in the case of having the guide line of (i), the cut line formed of the circle and the length of the radius of the circle from the center of the circle toward the circumference. When one end cut by one cut line of the length of the radius is bonded to an arbitrary position of the circle along the radius of the circle, The opening diameter decreases from the outer periphery toward the center, and a funnel structure is formed.
When having the guide line of (ii), the first cut line and the second cut line are cut, the end of the first cut line opposite to the side A side, An opening diameter from the side facing the one side A toward the one side A side by meshing with the end portion opposite to the other side B adjacent to the one side A in the second cut line. Becomes smaller and a funnel structure is formed.
In the case of having the guide line of (iii), the cut line is cut and the fold line is folded, and is surrounded by the fold line, the one side A, and another one side B adjacent to the one side A. The region formed is inserted into the region cut by the cut line. Since the cut line and the fold line are not parallel, the funnel structure is formed without being cylindrical.
In the case of having the guide line of (iv), when the first fold line and the second fold line are folded, they are sandwiched between the first fold line and the second fold line. The region becomes a ridge and a ridge structure is formed.
<12> Artificial bone granules, the artificial bone granules sealed and accommodated, and when the sealing is released, the sterilized inner container that functions as a transfer means capable of transporting the artificial bone granules to the affected area, An artificial bone granule filling kit comprising: an outer container containing a sterilized inner container.
In the artificial bone granule filling kit according to <12>, since the flexible sterilized inner container that accommodates the artificial bone granule functions as a transfer unit as it is, the artificial bone granule is not clogged in the transfer unit. Even if the artificial bone granules are transferred to the affected area and have any particle size, the artificial bone granules can be transferred without leaking from the target affected area. Further, since the sterilized inner container is used, a complicated process such as sterilization of the transfer means is not required, and the artificial bone granules are not contaminated. Furthermore, since the artificial bone granules are accommodated in a double-structured container comprising an outer container and a sterilized inner container, it is possible to efficiently prevent bacteria and the like from adhering to the artificial bone granules in the sterilized inner container. .

  The container for artificial bone granules of the present invention can prevent contamination of the artificial bone granules, and does not require a sterilization operation, has excellent operability, and is compatible with artificial bone granules of various particle sizes. It is a flexible container for artificial bone granules that can be transported without leaking from the target affected area, and can be transported without causing problems such as clogging of the artificial bone granules during transfer. It can be suitably used not only as a container for storing bone granules, but also as a transfer means for transferring the artificial bone granules to the affected area. Moreover, since the artificial bone granule filling kit of the present invention has the same effect as described above, it can be suitably used for procedures such as orthopedics, neurosurgery, plastic surgery, oral surgery and the like.

A One side arbitrarily selected B One other side adjacent to one side A C One side opposite to one side A D One side opposite to the other side B S First sheet X Folding line [17], one side A, other Area surrounded by side B Y Center of circle surrounded by cut line [7] Z Internal space g1, g2 Virtual line o Maximum length of opening r Maximum of at least one inner end facing opening Length i intersection (intersection of one side A and another one B)
a End of the first cut line [11] opposite to the side A side b End of the second cut line [12] opposite to the other side B side i-1 Intersection (on the side A (Intersection where one end meets one end on the other side B)
i-2 Intersection (intersection where the other end on the other side B intersects with one end on the one side C opposite to the one side A)
i-3, i-4 Any one point other than the end on the other side B i-5 Any one point other than the end on the arbitrarily selected side A of the first sheet S i-6 Other one side Any one point other than the end in B i-7 Any point on the side D facing the other side B i-8 Any point on the side A i-9 One side A arbitrarily selected on the first sheet S Any one point other than the end in i-10 Any one point other than the end in the other side B adjacent to one side A i-11 Intersection (intersection where one end in one side A and one end in the other side B intersect)
i-12 Intersection (intersection where the other end on the other side B and one end on the one side C opposite to the one side A intersect)
i-13, i-14 Arbitrary one point other than the end on the other side B m-1, m-2, m-3, m-4 Arbitrary one point on the side D opposite to the other side B n -1, n-3 Any one point other than the end on one side A n-2, n-4 Any one point other than the end on one side C facing one side A 1 First line 2 Second line 3 3rd line 4 4th line 5 5th line 6 6th line 7, 8, 13, 14, 18, 22, 23 Cut line 9 Cut line (cut line for filling part)
8-1 One end 10 and 19 cut by the cut line [8] Filling portion 11 First cut line 12 Second cut line 20 First fold line 21 Second fold line 15, 17, 25 Fold line 16 Filling part of artificial bone granule 100 Cut line for opening 200 Cut line for filling part

Claims (7)

A sterilized inner container that functions as a transfer means capable of containing the artificial bone granule in a sealed manner and transferring the artificial bone granule to the affected area when the sealing is released;
A container for artificial bone granules, comprising: an outer container for housing the sterilized inner container.   The container for artificial bone granules according to claim 1, wherein the sterilized inner container is a bag-shaped container comprising a first sheet and a second sheet. The sterilized inner container has an internal space in which the first sheet and the second sheet are in close contact to accommodate the artificial bone granules,
When an arbitrary selected side A is cut from an arbitrary point on the side A along the other side B adjacent to the side A,
The artificial bone granule storage container according to claim 2, wherein a maximum length of the excised opening is different from a maximum length of at least one inner end facing the opening in the internal space. The sterilized inner container has an internal space in which the first sheet and the second sheet are in close contact to accommodate the artificial bone granules,
When the first sheet has a guide line and is peeled off from the second sheet and then folded or cut along the guide line, the artificial bone granule can be transferred to the affected area. The container for artificial bone granules according to claim 2, which functions as a transfer means.   The container for artificial bone granules according to any one of claims 2 to 4, wherein the first sheet is one of paper and polyethylene nonwoven fabric.   The container for artificial bone granules according to any one of claims 1 to 5, wherein the transfer means is one of a funnel structure and a cage structure.   An artificial bone granule, a sterilized inner container that functions as a transfer means capable of containing the artificial bone granule in a sealed manner and transferring the artificial bone granule to an affected area when the sealing is released; and the sterilized content An artificial bone granule filling kit comprising: an outer container for housing a vessel.