JP2010018539A - Plaster for external use, and method for applying the same - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a plaster enabling its release liner to be easily peeled off even in the case of a patient whose fingertips are handicapped somewhat and grasping power has declined such as an elderly person, and also enabling a series of operations reaching to its application to be conducted easily, and enabling physical force necessary for releasing it to be controlled as well. <P>SOLUTION: The plaster for external use includes a substrate, a self-adhesive layer laminated on one side of the substrate, and a release liner attached releasably onto the self-adhesive layer. In this plaster, the release liner is composed of at least two release films, wherein (a) the first release film is attached onto the self-adhesive layer so as to cover the layer from one shorter side of the substrate to any site in the longitudinal direction of the substrate and has a taperedly formed tongue-piece-shaped part on the above any site side, and (b) the second release film is attached onto the self-adhesive layer so as to cover the exposed portion of the layer where the first release film is not attached, and a part of the second release film is superimposed on the first release film so as to cover the above tongue-piece-shaped part. <P>COPYRIGHT: (C)2010,JPO&INPIT

Description

  The present invention relates to an external patch such as a plaster, a tape and a pap. More specifically, the present invention relates to an external patch that can easily perform a series of operations from peeling of a release liner to sticking of a patch even in a patient whose hand is slightly inconvenient such as an elderly person and grip strength is reduced.

  An external patch is a very excellent dosage form in that it does not cause side effects or decrease in bioavailability of drugs that are problematic when taking oral preparations, and can be administered continuously. One. In recent years, external patches containing various anti-inflammatory analgesics have been developed and marketed as therapeutic agents for bruises, sprains, pain resulting from muscle fatigue, pain associated with stiff shoulders, low back pain, and joint pain.

  The external features of these external patches are a white and skin color support, a drug-containing adhesive layer spread on almost the entire surface of the support, and the entire surface of the adhesive layer 1 Generally, it is configured as a laminated structure composed of a release liner obtained by dividing one sheet or a plurality of sheets.

  If the release liner is a patch with the entire surface of the adhesive layer covered with a single release film, scratch the corners of the patch with nails, or place a nail between the adhesive layer and the release liner to remove a portion of the release liner. Method of exfoliating from the plaster layer and further exposing the part of the adhesive layer by pulling the part, and then applying the exposed part to the target affected area and applying the target to the target affected part while peeling the release liner Is mentioned.

  When the release liner is a patch in which the entire surface of the pressure-sensitive adhesive layer is coated with a release film that is divided into a plurality of sheets, in order to apply the patch, one release liner is peeled off from the divided portion of the release liner, A method of sticking all the patches to the affected area while peeling the remaining release liner after the site is attached to the target affected area can be mentioned.

  As described above, it is important to select an appropriate method for removing the release liner from the patch, depending on the physical characteristics of the patch, specifically the structure of the release liner. is there. However, it is very difficult to remove the release liner from the patch for patients, particularly elderly patients and the like who are somewhat inconvenient and have poor grip strength.

  Various patches that improve this problem have been proposed. For example, one using a V-shaped tube-like release film as the release film (Patent Document 1), one in which the uneven edge shape is alternately intersected (Patent Document 2), and one part of the release film folded back (Patent Documents 3 and 4), those provided with a protective layer between the release liner and the adhesive layer (Patent Document 5), those provided with a reinforcing portion on the release liner (Patent Document 6), and the like.

  However, the next problem is the weight when removing the release liner from the patch (the magnitude of the force required for peeling). The patch has an adhesive force sufficient to be applied to the affected area, and therefore a strong force is required to peel off the release liner. If you try to remove the release liner forcibly under such circumstances, the patch will be wrinkled or the adhesive layer surfaces will adhere to each other, and it will often not be applied correctly. The problem is greater with agents, and further improvements have been sought.

  On the other hand, when the adhesive strength of the patch was adjusted so as to reduce the influence on the release of the release liner, peeling of the patch from the affected area during application became a problem. Furthermore, the balance between the adhesive strength of the patch and the release force required to remove the release liner differs depending on the area, material, shape, etc. of the patch and release liner, and it was very difficult to adjust them in production. .

JP 2007-175300 A JP 2002-65726 A JP 2000-219622 A JP 2000-351727 A Japanese Utility Model Publication No. 7-44747 Japanese Utility Model Publication No. 7-42783

  The present invention solves the above-described problems, can easily peel the release liner from the patch even in patients with slightly reduced hand grip such as the elderly, and reduced grip strength, and further to the application of the patch It is an object of the present invention to provide a patch that can easily perform a series of operations and that can control the force required for peeling.

  As a result of intensive studies to achieve the above object, the present inventors have determined that a part of the release liner has, for example, a mountain shape, a wave-shaped straight line, a curved line, a combination thereof, or a tapered shape formed of an elliptical shape. It has been found that the release liner can be removed with a small force by providing a molded tongue piece and peeling the release liner from the tongue piece side. Further, the release liner having the tongue piece part can be easily removed from the patch by adjusting the shape of the tongue piece part, regardless of the area, material, shape, etc. of the patch and the release liner. The inventors have also found that the force required for removal can be controlled and completed the present invention.

That is, this invention solves the said subject,
In a patch comprising a support, an adhesive layer laminated on one surface of the support, and a release liner that is releasably attached to the adhesive layer, the release liner comprises at least two release films,
a) The first release film is attached to the adhesive layer so as to cover from one short side portion of the support to an arbitrary portion in the longitudinal direction, and at any portion in the longitudinal direction of the first release film. Has a tapered tongue piece on the side,
b) The second release film is attached to the adhesive layer so as to cover the exposed portion of the adhesive layer to which the first release film is not attached, and the first release film is partially covered with the tongue piece. It is an external patch characterized by being superimposed on a film,
After the second release film is removed, the exposed adhesive layer is applied to the affected part to be applied, and in that state, the tongue piece of the first release film is removed while being pulled, and the patch is applied simultaneously with the release. This is a method of applying an external patch.

  The external patch of the present invention has the ease of peeling of the release liner from the patch, like a conventional patch, and can release the release liner with a smaller force than the conventional patch. The release liner can be easily peeled off from the patch even in a patient whose hand is slightly inconvenient, such as an elderly person, and whose grip strength is reduced. Furthermore, since the force required for the peeling can be easily adjusted without using a special material or technique, it is very useful in actual production.

  The patch of the present invention comprises a support, an adhesive layer laminated on one surface of the support, and a release liner that is releasably attached to the adhesive layer, and the release liner includes at least two release films. It consists of Furthermore, a part of the release film is characterized by including a tongue piece portion formed in a tapered shape (hereinafter, the release film provided with the tongue piece portion is referred to as a “first release film”).

  As above-mentioned, the characteristic of the tongue piece part of the 1st peeling film of this invention is the taper shape which the width | variety becomes narrow as it goes to the front end side. Therefore, any shape that satisfies this condition may be used, and a shape other than the one formed in a mountain shape, a wave-like straight line, a curve, a combination thereof, or an elliptical shape may be used. By reducing the width of the tip of the tongue piece of the first release film, the force required to peel off the first release film can be reduced. Furthermore, the force can be easily controlled by adjusting the width and shape of the tongue piece.

  The tongue piece portion of the first release film of the present invention is preferably formed in a folded form of at least two folds in the longitudinal direction of the patch. This molding makes it easy to grasp the tip of the tongue piece with a finger and improves the feeling of use, and is preferable, as long as the shape satisfies this condition, it may be other than a double-folded, tri-folded, or more folded form. What attached another similar film to the 1st peeling film may be used.

  The thickness of the first release film of the present invention is 1-150 μm, preferably 10-100 μm. If it is this range, it will be easy to shape | mold in the folding form of two folds, three folds, or more. Further, if the thickness is less than 1 μm, the film itself is difficult to grasp due to its thinness, and wrinkles are likely to occur in the film during the production of the patch, which is not preferable. On the other hand, if it exceeds 150 μm, the cutting property in the production of the patch is lowered, which causes an increase in the cost of the patch itself, and at the same time, the release film itself is more expensive, which is not preferable from the viewpoint of cost. Absent.

  The tongue piece of the first release film of the present invention preferably has a finger hole and / or a slit. The finger hole and / or slit is preferable because the tip of the tongue piece can be easily gripped and the release film can be peeled off with a smaller force. If this condition is satisfied, the shape other than the hole and slit may be used. A method of applying anti-slip processing such as embossing or uneven processing to the surface of the substrate may be used.

  In the patch of the present invention, the first release film covers from the short side part of the patch to any part in the longitudinal direction, and the tongue piece part of the first release film is tapered. Therefore, a part of the adhesive layer is exposed. Therefore, in order to cover the tongue piece portion of the first release film and the exposed portion, a separate release film is provided from the side opposite to the adhesive layer side of the first release film (hereinafter referred to as “second release film”). .

  The shape of the 2nd peeling film of this invention should just cover the said exposed part, and what kind of shape and magnitude | size may be sufficient if this condition is satisfy | filled. In addition, if the shape is such as to cover the tongue piece portion of the first release film, the patch central side portion of the second release film overlaps the first release film, and the adhesive force does not act on the overlap portion. The second release film can be easily peeled off.

  Since the 2nd peeling film of this invention becomes easy to hold | grip a peeling film by shape | molding a finger hole and / or a slit similarly to a 1st peeling film, it is preferable. In addition, when providing finger passage holes and / or slits in any of the first release film and the second release film, if they overlap, the volatilization of the drug from the adhesive layer and the adhesion with the packaging material, etc., It is preferable that they do not overlap.

  The first and second release films of the present invention can use materials that are usually used in patches, for example, unstretched polypropylene, stretched polypropylene, polyethylene terephthalate, polybutylene terephthalate, polyethylene, polyester, polyurethane, Resin films such as polyvinyl chloride and polystyrene, paper, synthetic paper, those obtained by laminating synthetic resins alone or laminated, aluminum foil, those obtained by laminating vapor deposition films and the above materials, etc. can do. In addition, these single materials or composite materials that have been subjected to silicon processing, embossing, further printing, coloring, etc. may be used.

  The first and / or second release film of the present invention is printed with coloring and / or letters, arrows, figures, symbols, patterns, or a combination thereof in part or in whole for easy understanding of the peeling method. It is preferable to do.

  Hereinafter, embodiments of the patch of the present invention will be described with reference to the drawings. Note that the present invention is not limited to these embodiments.

  1 is a front view showing an embodiment of the patch according to the present invention, FIG. 2 is a view showing a state where the second release film is removed from the patch of FIG. 1, and FIG. 3 is a view of the patch of FIG. It is AA sectional drawing. In the figure, 1 is a patch, 2 is a first release film, 3 is a second release film, 4 is an adhesive layer, 5 is a support, 21 is a tongue piece, 22 is a finger hole in the first release film, 31 Indicates finger through-holes in the second release film. Note that the cross-sectional view of FIG. 3 is schematically drawn so that one embodiment of the present invention can be easily understood, and does not faithfully represent the dimensions (thickness / length) of actual products. The same applies to FIGS. 4 and 5 described later.

  As shown in FIG. 2, the patch according to the present invention has the first release film 2 attached so as to cover the adhesive layer 4 from the short side portion of the support to an arbitrary portion in the center. The 1st peeling film 2 has the tongue piece part 21 shape | molded by the taper shape in this arbitrary site | part side. Further, the tongue piece 21 is folded back in the vicinity of the center thereof, and a finger passage hole 22 is formed in the folded piece. And as shown in FIG. 1 and FIG. 3, the 2nd peeling film 3 is adhered so that the exposed part of the adhesion layer 4 and the tongue piece part 21 whole of the 1st peeling film 2 may be covered, and this 2nd peeling film A part of 3 is superposed on the first release film 2 at the tongue piece portion 21. Further, the second release film 3 is provided with finger passage holes 31 at two places.

  One example of the method of applying the patch of the present invention will be described. First, as shown in FIG. 4, the second release film 3 is removed by putting a finger into the finger passage hole 31 of the second release film 3 and pulling it as it is. Here, since the center side of the 2nd peeling film 3 has overlapped on the 1st peeling film 2, the adhesive force does not act on this overlap part. In the process of peeling the second release film 3, the contact area between the second release film 3 and the adhesive layer 4 is initially small and the contact area gradually increases. For these reasons, it is possible to peel easily with a light force.

  Next, as shown in FIG. 5, the exposed end portion of the adhesive layer 4 is affixed to the affected part to be affixed. In this state, a finger is put into the finger passage hole 22 of the first release film 2, and the first release film 2 is removed while pulling as it is. At this time, the patch can be smoothly applied to the affected area by gradually applying the adhesive to the affected area simultaneously with the peeling. Here, in the process of removing the first release film 2, the contact area between the first release film 2 and the pressure-sensitive adhesive layer 4 is initially small and the contact area gradually increases. As with, it can be easily peeled off with light force. Furthermore, since the tongue piece portion 21 of the first release film 2 is folded in half, it is easy to put a finger into the finger passage hole 22 and the first release film 2 is removed without touching the adhesive layer 4 with a finger. Is possible.

  The peeling force of the release film can be easily controlled by adjusting the lengths a1, a2, b and c in FIG. Specifically, the initial peeling force of the first release film can be reduced by shortening the length c. Moreover, if length a1 is lengthened, it will become easy to grasp the tongue piece part of a 1st peeling film, and if length a2 is set long with respect to length b, the sudden raise of the peeling force required for 1st peeling film removal will be carried out. And the peeling force of the second release film can be reduced.

  More specifically, in the case of the patch of this embodiment, by setting the range of c: b = 1: 2 to 2: 1 and a2: b = 0.5: 1 to 3: 1, It is preferable because the release liner can be easily peeled off from the patch even in a patient whose hand is slightly inconvenient and whose grip strength is reduced.

  6 and 7 show different embodiments of the patch of the present invention. As shown in the figure, the entire second peelable film 3 and the folded portion of the tongue piece 21 of the first peelable film 2 are colored, and each peeled film represents the peeling direction and the order of peeling. Numeric notation is printed. In this way, the usage method can be effectively presented to the user by coloring or printing symbols or the like.

  8 and 9 show different embodiments of the patch of the present invention. As shown in the figure, in this embodiment, slits 32 and 23 are provided in each release film instead of the finger-through holes. And in order to make it easier for the user to use, an arrow representing the position of the slit and the direction of peeling the release film and a numerical notation representing the order of peeling are printed. In the type provided with such a slit, the finger may be inserted into the slit during use and the release film may be peeled off in the same manner as that provided with the finger-through hole.

  FIG. 10 and FIG. 11 are different embodiments of the patch of the present invention, and the release film is composed of three sheets. As shown in FIG. 10, in the present embodiment, two first release films 2 are attached to an arbitrary portion closer to the center than the short side portions on both sides of the support 5, and around the center of the support 5. The adhesive layer 4 is exposed. And as shown in FIG. 11, the 2nd peeling film 3 shape | molded so that the exposed part of the adhesion layer 4 and the whole tongue piece part 21 of the two 1st peeling films 2 may be adhered.

  Although there is no restriction | limiting in particular as an adhesive contained in the adhesive layer of the patch of this invention, A rubber adhesive base, an acrylic adhesive base, a water-soluble adhesive base, etc. are mentioned.

  The rubber component of the rubber adhesive is selected from natural rubber, styrene-butadiene rubber, styrene-isoprene-styrene block copolymer, styrene-butadiene-styrene block copolymer, polyisoprene, polybutene, polyisobutylene, and butyl rubber. These can be used alone or in combination of two or more.

  Any acrylic adhesive base may be used as long as it is pharmaceutically usable, but acrylic acid / octyl acrylate ester copolymer, 2-ethylhexyl acrylate / vinyl pyrrolidone copolymer. Contained in solution, acrylic ester / vinyl acetate copolymer, 2-ethylhexyl acrylate / 2-ethylhexyl methacrylate / dodecyl methacrylate copolymer, methyl acrylate / 2-ethylhexyl acrylate copolymer resin emulsion, acrylic resin alkanolamine solution And an adhesive such as an acrylic polymer.

  Water-soluble adhesive bases include gelatin, pectin, agarose, alginate, xanthan gum, dextrin, methylcellulose, ethylcellulose, hydroxyethylcellulose, carboxymethylcellulose, polyvinyl alcohol, polyvinylpyrrolidone, polyethylene glycol, maleic anhydride copolymer, polyacrylic acid And natural polymers such as salts thereof or cross-linked products thereof or modified products thereof, or synthetic polymers or cross-linked products thereof.

  Furthermore, in addition to the said adhesive, the arbitrary component currently used for the well-known patch can be mix | blended with the patch of this invention. Examples of this optional component include antioxidants such as dibutylhydroxytoluene, softeners such as liquid paraffin, castor oil, cottonseed oil, palm oil, coconut oil, lanolin, and tackifiers such as rosin resins and terpene resins. Inorganic fillers such as petroleum resins and phenolic resins such as zinc oxide, aluminum oxide, titanium dioxide, silica gel, magnesium oxide, iron oxide, and zinc stearate can be used.

  Moreover, you may mix | blend the arbitrary active ingredient which can be used for a well-known patch in addition to the said adhesive and a mixing | blending component with the patch of this invention. Examples of this active ingredient include acetaminophenone, phenacetin, mefenamic acid, diclofenac sodium, flufenamic acid, aspirin, sodium salicylate, methyl salicylate, glycol salicylate, aminopyrine, alclofenac, ibuprofen, naproxen, flurbiprofen, ketoprofen, Amphenac sodium, mepyrazole, indomethacin, piroxicam, loxoprofen, thiaprofen, acemetacin, felbinac, sulindac, etodolac, tolmetine, ampiroxicam, azapropazone, anti-inflammatory analgesics such as valdecoxib, rofecoxib, anticorticone, triamcinoprenone, dexamethasone Inflammatory agent, ethyl aminobenzoate, lidocaine Local anesthetics such as lidocaine hydrochloride, tetracaine hydrochloride, brocaine hydrochloride, dibucaine hydrochloride, oxybuprocaine hydrochloride, propitocaine hydrochloride, diphenhydramine hydrochloride, chlorpheniramine maleate, promethazine, antihistamines such as cyproheptadine hydrochloride, diphenylpyraline hydrochloride, salicylic acid, cyclo Vitamins such as pirox olamine, agents for parasitic skin diseases such as coroconazole hydrochloride, emollients such as urea, calcitriol, thiamine hydrochloride, sodium riboflavin phosphate, pyridoxine hydrochloride, nicotinamide, panthenol, ascorbic acid And the like.

  The support of the patch of the present invention is preferably made of a material that does not affect the release of the drug, and various polymer films and sheets or laminates, porous bodies, foams, paper, cloth, nonwoven fabrics, etc. And non-stretchable ones are used. In addition, as the material, for example, polymer materials such as polyethylene terephthalate, polybutylene terephthalate, polyethylene, polypropylene, polybutadiene, ethylene vinyl acetate copolymer, polyvinyl chloride, polyester, nylon, polyurethane, and natural materials such as cellulose and cotton. Etc.

  The method for producing the external patch of the present invention is not particularly limited, and can be produced using a known method for producing a patch. For example, each component to be blended in the adhesive layer is heated and melted or dissolved in a solvent, and applied and spread on a support by an appropriate coating method to provide an adhesive layer, and the first and second release films are provided on the adhesive layer. The method of pasting is mentioned.

  EXAMPLES Hereinafter, although an Example and a test example are given and this invention is demonstrated further in detail, this invention is not restrict | limited at all by these Examples. In the examples, “parts” means all parts by mass.

Example 1
Patch preparation:
An external patch (the product of the present invention) was obtained by the following formulation and production method.

(How to)
Styrene-isoprene-styrene block copolymer 30.0 parts (trade name Clayton D-KX401)
Liquid paraffin 31.0 parts Alicyclic saturated hydrocarbon resin 30.0 parts (Brand name Alcon P-100)
Polyethylene glycol 6000 6.0 parts (trade name Macrogol 6000)
l-menthol 2.0 parts dibutylhydroxytoluene 1.0 part

(Production method)
Styrene-isoprene-styrene block copolymer The following components were heated and mixed to obtain a uniform melt. The obtained melt was applied to a support (nonwoven fabric) using a coating machine so that the paste weight was 100 g / m ² . A first release film (polyethylene terephthalate film with a thickness of 50 μm) and a second release film (polyethylene terephthalate film with a thickness of 50 μm) shown in FIG. 1 and FIG. 2 are bonded to the coated adhesive layer, respectively. It cut | judged to a magnitude | size and obtained the patch for external use.

Comparative Example 1
Patch preparation:
An external patch (comparative product) was obtained by the following formulation and production method.

(How to)
Styrene-isoprene-styrene block copolymer 30.0 parts (trade name Clayton D-KX401)
Liquid paraffin 31.0 parts Alicyclic saturated hydrocarbon resin 30.0 parts (Brand name Alcon P-100)
Polyethylene glycol 6000 6.0 parts (trade name Macrogol 6000)
l-menthol 2.0 parts dibutylhydroxytoluene 1.0 part

(Production method)
Styrene-isoprene-styrene block copolymer The following components were heated and mixed to obtain a uniform melt. The obtained melt was applied to a support (nonwoven fabric) using a coating machine so that the paste weight was 100 g / m ² . A first release film (polyethylene terephthalate film having a thickness of 50 μm) and a second release film (polyethylene terephthalate film having a thickness of 50 μm) shown in FIG. 12 are bonded to the coated adhesive layer, respectively, to a size of 70 mm × 100 mm. Cut to obtain an external patch.

Test example: Evaluation of sticking ability of a patch About ease of sticking a patch using the product of the present invention and a comparative product for 10 adult males who have felt that it has been difficult to stick when applying a patch. The test was conducted. As shown in FIG. 12, the comparative product used was obtained by adhering two rectangular release films from both ends of the support, folding one release film end side in the center in two, and the folded portion and adhesive Another release film is attached so as to cover the exposed portion of the layer. The test method consists of (1) removing the second release film of the patch, (2) applying the exposed end of the adhesive layer to the waist, and (3) applying the patch while removing the first release film. About the pasting property of the patch using the product of the present invention and the comparative product at this time The product of the present invention was easier to apply, B. The comparative product was easier to apply, C.I. It did not change and was evaluated.

  As a result of the test, all 10 out of 10 A. It was evaluated that the product of the present invention was easier to apply, and it was confirmed that the adhesiveness of the patch was improved by using the product of the present invention.

It is a front view which shows one Embodiment of the patch of this invention. It is a front view which shows the state which removed the 2nd peeling film of the patch of FIG. It is sectional drawing which follows the AA line of the patch of FIG. It is a bottom view which shows the state which peels the 2nd peeling film of the patch of FIG. It is a bottom view which shows the state of peeling of the 1st peeling film of the patch of FIG. 1, and the sticking of a patch. It is a front view which shows another embodiment of the patch of this invention. It is a front view which shows the state which removed the 2nd peeling film of the patch of FIG. It is a front view which shows another embodiment of the patch of this invention. It is a front view which shows the state which removed the 2nd peeling film of the patch of FIG. It is a front view which shows another embodiment of the patch of this invention. It is a front view which shows the state which removed the 2nd peeling film of the patch of FIG. It is a perspective view which shows the form of a comparative product.

Explanation of symbols

DESCRIPTION OF SYMBOLS 1 ... Patch 2 ... 1st peeling film 3 ... 2nd peeling film 4 ... Adhesive layer 5 ... Support body 21 ... Tongue piece part 22 ... Finger penetration hole 23 of 1st peeling film ... Slit 31 of 1st peeling film ... 1st Finger release hole 32 of the second release film ... Slit of the second release film

Claims (12)

In a patch comprising a support, an adhesive layer laminated on one surface of the support, and a release liner that is releasably attached to the adhesive layer, the release liner comprises at least two release films,
a) The first release film is attached to the adhesive layer so as to cover from one short side portion of the support to an arbitrary portion in the longitudinal direction, and at any portion in the longitudinal direction of the first release film. Has a tapered tongue piece on the side,
b) The second release film is attached to the adhesive layer so as to cover the exposed portion of the adhesive layer to which the first release film is not attached, and the first release film is partially covered with the tongue piece. An external patch characterized by being superposed on a film.   The external patch according to claim 1, wherein the tongue piece portion of the first release film has a mountain shape, a wave-like straight line, a curved line, a combination thereof, or a semi-elliptical tapered shape.   The external patch according to claim 1 or 2, wherein the tongue piece portion of the first release film is in a folded form of at least two folds in the longitudinal direction of the support.   The external patch according to any one of claims 1 to 3, wherein the tongue piece portion of the first release film and / or the second release film has a finger hole and / or a slit. In a patch comprising a support, an adhesive layer laminated on one surface of the support, and a release liner that is releasably attached to the adhesive layer, the release liner comprises two first release films and one sheet A second release film of
a) One of the first release films is opposed to one short side of the support, and the other of the first release film is opposed to the other short side of the support. And at least one of the first release films has a tapered tongue piece on an arbitrary site side in the longitudinal direction,
b) The second release film is attached to the adhesive layer so as to cover the exposed portion of the adhesive layer where the two first release films are not attached, and a part of the second release film covers the tongue piece. An external patch characterized by being superimposed on a first release film.   6. The external patch according to claim 5, wherein one or both tongue pieces of the first release film have a mountain shape, a wave-shaped straight line, a curved line, a combination thereof, or a semi-elliptical taper shape. Agent.   The patch for external use according to claim 5 or 6, wherein one or both tongue pieces of the first release film are in a folded form of at least two folds in the longitudinal direction of the support.   The external use according to any one of claims 5 to 7, wherein one or both of the tongue pieces and / or the second release film of the first release film have finger through holes and / or slits. Patch.   The first release film and / or the second release film is made of unstretched polypropylene, stretched polypropylene, polyethylene terephthalate, polybutylene terephthalate, polyethylene, polyester, polyurethane, polyvinyl chloride, polystyrene plastic film, paper, synthetic paper, synthetic resin. The patch for external use according to any one of claims 1 to 8, wherein the patch is composed of a single or laminated composite film, or a composite film obtained by laminating an aluminum foil or a vapor deposition film.   2. A part or all of the first release film and / or the second release film is colored and / or printed with characters, arrows, figures, symbols, patterns, or combinations thereof. The external patch according to any one of Items 9 to 9.   The external patch according to any one of claims 1 to 10, wherein the first release film has a thickness of 1 to 150 µm.   After the second release film is removed, the exposed adhesive layer is applied to the affected part to be applied, and in that state, the tongue piece of the first release film is removed while being pulled, and the patch is applied simultaneously with the release. The method for applying an external patch according to any one of claims 1 to 11.

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