JP2009539466A - Lotion wipes containing anti-sticking agents and performance improvers - Google Patents

Abstract

  An anti-sticking agent and a performance-enhancing agent that may be mixed in an aqueous medium that helps prevent dirt and excrement from adhering to the skin. The substrate may be utilized to help deliver anti-sticking and performance enhancing agents to the skin.

Description

  A lotion wipe comprising a substrate and a lotion in contact with the substrate, wherein the lotion comprising an anti-sticking agent and a performance enhancing agent is used to deliver improved body cleansing performance There is a case. Lotions can help reduce the adhesion of dirt or exudates to the skin.

  Skin cleansing is a physical hygiene problem that is not always easily solved. Dry tissue products are the most commonly used cleansing products after defecation, after urination, and during menstruation. Dry tissue products are also commonly used to remove dirt such as food and garbage from the skin. Dry tissue products, such as those commonly used, are commonly referred to as “toilet paper”, “toilet tissue”, or “paper towels”. In addition to the use of dry tissue products, moistened like a wet towel for cleansing the dirty face and body, and the anus, genital area, perineum, and perianal area after excretion The use of substrates is becoming increasingly frequent. So-called “wet towels” are generally fiber structures impregnated with water or oil-based lotions.

  For purposes of this document, the anus, perineum, perineum, and vulva are all terms that refer to the pelvic region of the body between and surrounding the anus and the external genitalia.

  Both the perineum and the vulva are marked by the presence of fine creases / folds (grooves) and hair follicles, both of which make these regions more difficult to cleanse. During defecation, fecal material tends to be excreted through the anus and accumulate in difficult to reach areas such as around the base of the hair and in the grooves on the skin surface. During menstruation, menstrual blood may accumulate on the skin and hair after use of the sanitary napkin. As feces or menstrual substances are exposed to air or dehydrated by contact with absorbent devices such as tissue paper, diapers, or sanitary napkins, it adheres more firmly to the skin and hair . Subsequent removal of residual dehydrated exudate may be even more difficult and may result in poor cleansing. Among the inconveniences that occur when not fully cleansed are inflammation, redness, desquamation, infections, unpleasant odors, or other types of physical discomfort or health related problems.

  People suffering from pathological conditions (eg, sputum, laceration, cryptitis, etc.) are even more susceptible to the drawbacks described above. The benefits of good cleansing after defecation, menstruation and urination are very relevant for infants, toddlers, children and adults due to common hygiene concerns. Cleansing must be efficient from the standpoint of residue removal and must be gentle from the standpoint that cleansing does not cause irritation. Wet towels provide an answer to these basic requirements.

Compared to dry tissue products, wet towels have several benefits:
-Enabling better lubrication during use of the wipe, thereby reducing the roughness of the cleansing operation;
Hydrating the residues and thus enhancing their removal from the skin or hair;
Hydrating the skin tissue; and-being able to deliver a sedative or protective lotion to the skin that can remain on the skin after a cleansing operation.

Wet towel manufacturers:
-Protecting the skin from irritation and epidermal peeling while enhancing dirt removal;
-Attempts have been made to develop wipes that deliver the right balance between otherwise conflicting concepts such as long lasting comfortable cleanliness while avoiding a greasy feel on the skin.

  There is still a need for wet towels that not only effectively clean, but also reduce or prevent dirt or exudates from attaching to the skin at the same time. These wipes greatly facilitate cleansing. The promotion of cleansing with such wipes may be reflected by a reduction in the adherence of dirt or exudates on the skin from subsequent damage. As a result, the amount of dirt or exudate on the skin may be reduced at the next clean, and easier removal of the dirt or exudate from the skin will result in less scratching damage, dirt or exudation. This may result in a reduction of the stain on the skin of the object and / or an improved acquisition / retention of soil or exudate on a substrate such as a wet towel or in an absorbent article. The net result is that an individual may require less time and effort to achieve a satisfactory clean condition.

  To the skin of dirt or exudates in a manner that is not conscious by the individual using the wipe, i.e. without having to change habits like using a separate wipe or leaving an undesirable greasy layer on the skin surface There is a further need for wet towels that substantially reduce or prevent the deposition of water.

  A lotion wipe comprising a substrate and a lotion in contact with the substrate, the lotion comprising an anti-sticking agent and a performance enhancer. Lotion may be effective in leaving less than about 10% by weight residual soil or exudates as measured by the Anti-Stick Screening Method. The anti-sticking agent may be present at a concentration of up to about 50% by weight of the lotion composition. The performance enhancer may be present at a concentration of about 3% or less by weight of the lotion composition. The anti-sticking agent may be water-soluble.

  The anti-sticking agent may be selected from the group consisting of non-polymeric anti-sticking agents, polymeric anti-sticking agents, alkoxylated polyols, and combinations thereof. The performance improver may be selected from the group consisting of film formers, deposition aids, rheology modifiers, and combinations thereof.

  The lotion may further comprise an emollient and a surfactant.

  The product may include a container for storing a lotion wipe.

  The method of preventing dirt or exudates from sticking to the skin may comprise the step of contacting the lotion wipe with the skin.

  The ease with which dirt and excrement are removed from the skin may be related to the strength of the adhesion interaction between the dirt or exudate and the skin surface. Reduced adherence of dirt or exudates to the skin may allow easier removal of dirt or exudates. Various substances (hereinafter referred to as anti-sticking agents) have been identified that may reduce the strength of dirt or exudate attachment to the skin. Additional materials (hereinafter referred to as “performance enhancers”) may improve the effectiveness of anti-sticking agents and allow the use of anti-sticking agents at lower w / w concentrations in lotion compositions. It has been confirmed that there are cases. Substrates in contact with a lotion containing anti-sticking agents and performance enhancing agents may reduce the strength of dirt or effluent adhesion to the skin. Such a combination of substrate and lotion may be a lotion wipe.

  As defined herein, “weight” or “w / w” refers to the weight of the referenced component versus the weight of all materials in the reference. Thus, the use of “w / w” in a substrate refers to the weight of the individual substrate components versus the weight of the entire substrate. The use of “w / w” in a lotion refers to the weight of the individual lotion components versus the total weight of the lotion. The use of “w / w” in water solubility refers to the weight of the material versus the total water in which the material is dissolved. The use of “w / w” for artificial bowel movement (ABM) refers to the weight of the artificial stool remaining on the skin versus the total weight of the artificial stool applied to the skin.

The substrate lotion may be in contact with or associated with the substrate for use in cleansing and removing dirt or exudates. “Substrate” is a general term that describes a material that is generally a nonwoven material and is used to cleanse body parts. In particular, many currently available substrates may be targeted for perianal cleansing after defecation. Other substrates may be usable for cleansing the face or other body parts.

  The substrate may be a nonwoven material. “Nonwoven fabric” as used herein refers to an assembly of continuous fibers, coextruded fibers, non-continuous fibers, and combinations thereof, without weaving or knitting, spunbonding, carding, melt blowing, air laying, wet laying, Refers to fiber structures made by coform, or other such processes known in the art for such purposes. Nonwoven structures may include one or more layers of such fiber assemblies, and each layer may include continuous fibers, coextruded fibers, non-continuous fibers, and combinations thereof.

  The substrate fibers may be any natural cellulosic material and / or fully synthetic material. Examples of natural fibers may include cellulose natural fibers such as fibers from hardwood sources, coniferous sources, or other non-wood plants. Natural fibers may include cellulose, starch, and combinations thereof. Non-limiting examples of suitable cellulose natural fibers include wood pulp, typical northern softwood Kraft, typical southern softwood Kraft, typical CTMP, typical deinking, Examples include, but are not limited to, corn pulp, acacia, eucalyptus, aspen, reed pulp, birch, maple, radiator pine, and combinations thereof. Other sources of natural fiber from plants include albardine, esparto, wheat, rice, corn, sugarcane, papyrus, burlap, reed, sabia, raffia, bamboo, sidal, kenaf , Abaca, sun hemp, rayon (also known as viscose), lyocell, cotton, cannabis, flax, ramie, and combinations thereof. Still other natural fibers may include fibers from other natural non-plant sources such as down, feathers, silk, cotton, and combinations thereof. Natural fibers may be mechanically or chemically treated or otherwise modified to provide desirable characteristics, or in a form that is substantially similar to the form in which they can be found in nature. There may be. For the developments described herein, mechanical and / or chemical manipulation of natural fibers does not exclude them from the category considered natural fibers.

  The synthetic fiber may be selected from the group consisting of polyester (eg, polyethylene terephthalate), polyolefin, polypropylene, polyethylene, polyether, polyamide, polyester amide, polyvinyl alcohol, polyhydroxyalkanoate, polysaccharide, and combinations thereof. However, the present invention is not limited to these. In addition, synthetic fibers are composed of a single component (ie, a single synthetic material or mixture makes up the entire fiber), two components (ie, the fibers are divided into regions, and the regions are two or more different synthetic materials or The mixture as well as coextruded fibers and core-sheath fibers), and combinations thereof. It is also possible to use bicomponent fibers. These bicomponent fibers can be used as component fibers of the structure and / or they may be present to act as binders for other fibers present in the fiber structure. . Any or all of the synthetic fibers may be treated before, during, or after manufacture to change any desired properties of the fibers.

  In certain embodiments, it may be desirable to have a special combination of fibers to provide the desired characteristics. For example, it may be desirable to have fibers of a particular length, width, roughness, or other characteristics combined or separated from one another in a particular layer. The fibers may be of virtually any size and may have an average length of about 1 mm to about 60 mm. Average fiber length refers to the length of individual fibers when straightened. The fibers may have an average fiber width that is greater than about 5 micrometers. The fibers may have an average fiber width of about 5 micrometers to about 50 micrometers. The fiber may have a roughness greater than about 5 mg / 100 m. The fiber may have a roughness of about 5 mg / 100 m to about 75 mg / 100 m.

  In addition, it may be desirable for the fibers to have specific compositional characteristics. For example, if the lotion contains a hydrophilic (ie, water-soluble) component that is intended to be finally applied to the skin during cleansing, the hydrophilic component may become a fiber by including a hydrophobic material. It may be desirable to reduce the tendency to adhere to and thereby reduce their availability to the skin. Without being bound by theory, it is believed that lotion ingredients may split between lotion and fiber during storage and between lotion, fiber and skin during cleansing. . If the lotion contains a hydrophilic component that will be applied to the skin during cleansing, the use of hydrophobic fibers in the substrate will break apart and subsequent delivery of the hydrophilic component to the skin. help.

  The hydrophobic fiber can be any material such as those selected from the group consisting of polyester (eg, polyethylene terephthalate), polyolefin, polypropylene, polyethylene, polyether, polyamide, polyesteramide, and combinations thereof, It is not limited to these. In addition, hydrophobic fibers are composed of a single component (ie, a single synthetic material or mixture makes up the entire fiber), two components (ie, the fiber is divided into regions, and the regions are two or more different synthetic materials). Or a mixture thereof, and may include co-extruded fibers and core-sheath fibers), and combinations thereof.

  The fibers may be circular in cross section, dogbone, triangular (ie, triangular cross section), trilobal, ribbon, or other shapes typically produced as short fibers. Similarly, the fiber can be a conjugate fiber such as a bicomponent fiber. The fibers may be crimped or a finish such as a lubricant may be applied.

  The substrate material may also be treated to improve its flexibility and texture. Substrates include, but are not limited to, physical treatments such as hydro-molding, hydro-embossing, ring rolling (US Pat. No. 5,143,679 (Weber et al. As described in U.S. Pat. No. 5,518,801 (issued on May 21, 1996). Consolidation (US Pat. No. 5,914,084 (Benson et al., Issued June 22, 1999)); 6,114,263 (Benson et al., September 2000) No. 6,129,801 (Benson et al., Issued on October 10, 2000) and No. 6,383,431 (Dobrin et al., Issued on May 7, 2002) As described in) Stretch aperturing (US Pat. No. 5,628,097 (Benson et al., Issued May 13, 1997); 5,658,639 (Curro et al., August 1997) 19th issue), and 5,916,661 (as described in Benson et al., Issued June 29, 1999); differential elongation (US Publication No. .) 2003 / 0028165A1 (as described in Curro et al., Published Feb. 6, 2003); and other solid state forming techniques (US Publication No. 2004 / 0131820A1 (Turner). (Turner et al., Published July 8, 2004), and US Publication No. 2004 / 0265534A1 (Curro et al., Published December 30, 2004). Zone activation, etc .; chemical treatment, such as, but not limited to, making part or all of the substrate hydrophobic and / or hydrophilic; heat treatment, such as, but not limited to May be subjected to various treatments such as hot embossing, fiber softening by heating, thermal bonding, etc .; and combinations thereof.

  Without being bound by theory, the textured substrate also allows for easy removal of excrement by increasing the ability to grab or otherwise lift exudate from the skin during cleansing. It is thought that there may be. Without limitation, continuous wet forming elements, hollow forming elements, solid forming elements, circular, square, rectangular, oval, elliptical, distorted circles, spirals, spiral shapes, cross hatches, pebbles, aligned circles ), Connected distorted circles, semicircles, wavy lines, bubble lines, puzzles, leaves, fringed leaves, plates, connecting circles, changing curves, dots, honeycombs, and combinations thereof Any one of a number of texture elements may be useful to increase the ability to grab or otherwise lift exudates from the skin during cleansing. The texture element may be a hollow element. The texture elements may be connected to each other. The texture elements may overlap each other.

The substrate may have a basis weight from about 15, 30, 40, or 45 g / m ² to about 65, 75, 85, 95, or 100 g / m ² . Suitable substrates are viscose and polypropylene fibers having a basis weight of 58 g / m ² , as available as FIBRELLA ™ 3160 from Suominen, Tampere, Finland. A carded nonwoven fabric comprising a 40/60 blend of FIBRELLA (TM) 3160 is a 58 g / m < ² > nonwoven web containing 60 wt% 1.5 denier polypropylene fibers and 40 wt% 1.5 denier viscose fibers. Another suitable material may be FIBRELLA ™ 3100, which includes 50% by weight 1.5 denier polypropylene fiber and 50% by weight 1.5 denier viscose fiber. 62 g / m ² of nonwoven web. In both of these commercially available fiber webs, the average fiber length is about 38 mm. Another suitable material for use as a substrate is SAWATEX ™ 2642, such as is available from Sandler AG, Schwarzenbach / Salle, Germany. May be. Yet another suitable material for use as a substrate may have a basis weight of from about 50 g / m ² to about 60 g / m ² and has a 20/80 blend of viscose and polypropylene fibers. May be. The substrate may also be a 60/40 blend of pulp and viscose fibers.

  In one embodiment, the surface of the substrate may be essentially flat. In another embodiment, the surface of the substrate may optionally contain raised and / or lowered portions. These can be in the form of logos, indicia, trademarks, geometric patterns, images of the surface that the substrate is intended to clean (ie, infant's body, face, etc.). They may be randomly arranged on the surface of the substrate or may be any form of repetitive pattern.

  In another embodiment, the substrate may be biodegradable. For example, the substrate can be made from a biodegradable material such as polyesteramide or high wet strength cellulose.

Lotion “Lotion” as used herein refers to a composition comprising a support such as water. The lotion further includes an anti-sticking agent and a performance enhancing agent. Additional optional ingredients may be added to the lotion as desired to form a lotion composition, as described herein. Lotions may form a film on the surface of the skin and may provide increased repellency of residual dirt or exudates at low concentrations of anti-sticking agents.

Performance enhancer A performance enhancer, as defined herein, is the adhesion, wettability of a coating that may be formed on the skin surface after treatment with an anti-stick agent alone or with a lotion containing an anti-stick agent. A substance that improves robustness, uniformity, stability, or a combination thereof.

  Without being bound by theory, performance enhancers may improve the effectiveness of anti-sticking agents or lotions containing anti-sticking agents, and thereby reduce the w / w concentration of anti-sticking agents used. It is thought that there are cases where it can be reduced. This improves the adhesion of the anti-sticking agent or lotion to the skin surface by allowing the anti-sticking agent or lotion to more easily spread over the skin surface and form a coating, and then wash or scrub it off. By making it more durable or resistant, the anti-sticking agent or lotion can make the skin formed more uniform by allowing the skin surface to wet more effectively. It is speculated that the resulting coating may be made more resistant to rupture, or a combination thereof.

  Performance enhancers may include, but are not limited to, materials that may generally be known as film formers, deposition aids, rheology modifiers, or combinations thereof.

  Film formers may include, but are not limited to, polyvinyl pyrrolidone, hydroxypropyl cellulose, ethyl cellulose, methyl hydroxypropyl cellulose, methyl ethyl cellulose, copolymer condensates including ethylene oxide and propylene oxide, and polyethylene glycol. . Other suitable film formers include gums such as agar, guar gum, gum arabic, gum arabic uses, gati gum, karaya gum, hydroxypropyl guar gum, and xanthan gum; alginates such as calcium alginate and alginic acid Calcium-sodium; protein film formers such as pectin, albumen, polyamino acids (eg polylysine) and gelatin; and waxes such as carnauba wax. Combinations of the above may also be used.

  Rheology modifiers are compounds that can affect the way other materials or compositions deform and flow. Rheology modifiers may increase the viscosity of the lotion composition, may provide “structure” to the lotion composition, may help to stabilize the lotion composition on the substrate, and the skin May facilitate the movement of the lotion composition to the surface and may increase the uniformity of the coating of the lotion composition on the skin.

  The rheology modifier may also affect the rheological properties of the lotion composition, as the viscosity of the lotion composition may change as a function of the shear force applied to the lotion composition. Application of a lotion composition to a surface (eg, skin) typically involves a “wiping” or “rubbing” action. This action may increase the shear force and pressure experienced by the lotion composition. In the case of shear-thinning rheological properties (ie, increasing shear force reduces the viscosity of the lotion composition), the viscosity of the lotion decreases with increased shear force of “wiping” or “rubbing”. Which may allow better transfer to the skin as well as a better lubricating effect.

Non-limiting examples of rheology modifiers include:
-Polysaccharide units such as cellulose, xanthan gum, diutan gum, carrageenan, gellan gum, welan gum, pectin, sclerotium gum, starch, galactoarabinan, alginates, and variations thereof;
A homopolymer of acrylic acid;
-Acrylic acid crosslinked with polyfunctional compounds, such as carbomers and acrylate crosspolymers;
-Copolymers such as acrylic acid, acrylate esters, maleic acid, etc., generally known as alkali swell emulsions (ASE) group;
-Hydrophobically modified copolymers, such as acrylic acid, acrylate esters, maleic acid, etc., generally known as the group of hydrophobically modified alkali swelling emulsions (HASE);
-Various lengths of polyethylene glycol units, commonly known as the group of hydrophobically modified ethoxylated urethane resins (HUR), linked by urethane linkages and terminated by hydrophobic end groups; and-rheology modifiers comprising combinations thereof. However, it is not limited to these.

  In certain embodiments, the rheology modifier may be Keltrol ™, such as that available from CP Kelco, San Diego, California. In certain embodiments, the rheology modifier may be Ticaxan ™, such as that available from TIC Gums, Belcamp, Maryland. In certain embodiments, the rheology modifier may be Rhodicare ™ D, such as that available from Rhodia, Cranbury, NJ. Additional examples of rheology modifiers include Ultrez ™ -10, Carbomer, and Pemulen ™, both of which are available from Noveon, Cleveland, Ohio. ) TR-2, acrylate crosspolymers, but are not limited to these.

  The performance enhancer is about 0.05%, 0.1%, 0.15%, 0.18%, 0.2%, 0.3%, 0.4%, or 0.5% to about 1% It may be used in 2% or 3% weight% (w / w).

  It should be noted that some film formers, deposition aids, and rheology modifiers can have multiple functions, for example, rheology modifiers may improve both adhesion and film formation. is there.

  While specific performance enhancers have been described and described, it will be apparent to those skilled in the art that various other performance enhancers may be used without departing from the spirit and scope of the present invention.

Anti-sticking agent As used herein, the term “anti-sticking agent” is a water-soluble that may help reduce or prevent the attachment of dirt or exudates to the body surface, thereby facilitating subsequent cleaning. Refers to a substance. “Soil” as used herein refers to material from external sources such as garbage and food. “Exudate” as used herein refers to substances from internal sources such as urine, menstrual blood, feces, and mucus.

  Without being bound by theory, anti-sticking agents may reduce the adhesion between the soil or exudate and the skin surface, so that the adhesion is less than the cohesive force within the soil or exudate. In some cases, it is believed that application of shear forces generated, for example, by wiping, allows the soil or exudate to be separated from the skin surface. This mechanism is not intended to explain the means by which all anti-sticking agents described herein function. Other possible mechanisms for reducing skin adhesion will be apparent to those skilled in the art.

  The use of water-insoluble materials to reduce the adherence of dirt or exudates to the skin is known in the art. Substances such as silicones, mineral oils, petrolatum, vegetable oils, and other hydrophobic emollients are known in the form of emulsions in wet towels. Examples of such emulsions are US Pat. No. 6,083,854 (Bogdanski et al., Issued July 4, 2000); No. 5,648,083 (Blieszner et al., July 1997). 15th), and 6,440,437 (Krzysik et al., Issued August 27, 2002).

While water-insoluble materials such as those described above may deliver some anti-stick performance:
-They often leave an undesirable greasy or slimy feeling on the skin; and-they are typically slimy, reducing the interaction between cleansing tools and dirt or exudates and soaking And suffers from several serious drawbacks which can result in poor cleaning.

Water soluble anti-sticking agents overcome many of these drawbacks. For purposes of the present invention, an anti-sticking agent is water soluble when about 0.01%, 0.1%, 0.5%, or 1.0% by weight or more dissolves in water at 25 ° C. It is considered sex. Water soluble anti-sticking agents may have the following advantages:
-They typically do not leave a greasy feel on the skin; and-they typically do not slip as well as water-insoluble anti-sticking agents, as well as better cleanliness and less staining. May result.

  In contact with a lotion that may deliver good repellency of soil or exudate while utilizing a low concentration level of anti-sticking agent, such as anti-sticking agent at a concentration of about 10% by weight or less in the lotion. There is a further need for good substrates. Such lotioned substrates incorporate anti-sticking agents into the lotion due to the reduced amount of anti-sticking agent required to deliver benefits and due to the water solubility of the anti-sticking agent. May be cost effective. In addition, anti-sticking agents may result in cleansing benefits such as dirt or exudate repellency, and result in sensory imperfections on the skin such as greasy or slimy coatings. There may not be. Consumers may prefer substrates that can deliver anti-stick benefits while being used for daily cleansing, i.e., consumers may add additional steps to the cleansing process, e.g., one substrate for cleaning. In use and cleanliness, the use of additional substrates that provide poor anti-stick benefits may be unfavorable. An example of a wipe containing a hydrophobic anti-sticking agent that is poorly cleaned and needs to be used as a separate wipe is described in US2005 / 02444480A1.

  To determine whether the adhesion interaction is affected by surface treatments or other factors, the strength of the adhesion between the two materials may be analyzed by a variety of methods. Examples of adhesion tests to determine whether a process reduces adhesion between two materials (eg, by reducing adhesion to less than cohesive force) are referenced in ASTM D2919, ASTM D3528, and therein. Or the related methods described. Such methods may test the strength of adhesion through the application of shear forces.

  A method for assessing the adherence of dirt or exudates to the skin surface is detailed herein. Some anti-sticking agents used at low concentrations (eg in lotions) may provide anti-stick benefits on the skin, but the magnitude of this anti-stick benefit is greatly reduced on artificial surfaces. It has been discovered that Without being bound by theory, factors such as skin wettability, surface energy, and surface chemistry have important implications for the formation of effective anti-stick coatings containing specific water-soluble anti-stick agents. It is believed that.

  Tests for assessing the adhesion of dirt or exudates to the skin are described in detail in the Test Methods section. Briefly, the Anti-Stick Screening Method treats the skin surface with a defined amount of anti-sticking agent or lotion containing anti-sticking agent. A defined amount of artificial glue-like stool (“ABM”) is applied. The ABM is covered with a square piece of paper and pressed against a defined amount of time with a defined force. The paper is then slowly peeled off using forceps. The paper is tared before application of ABM and reweighed after removal from the skin. The percentage of residual ABM on the skin is calculated as the weight of artificial stool (ABM) remaining on the skin versus the weight of the artificial stool that was first applied to the skin. ABM, like the actual infant BM, cannot agglomerate, resulting in some of the ABM remaining on the skin surface and some of the ABM remaining on the piece of paper. The more effective the anti-sticking agent or lotion containing the anti-sticking agent, the less residual ABM on the skin surface. Artificial ABMs are utilized in the Anti-Stick Screening Method, but artificial ABMs may correlate in physical properties with dirt or exudates. The percentage of residual artificial ABM may therefore be used as a measurement equivalent to the percentage of residual soil or exudate.

  Anti-sticking agents that are beneficial for use are about 10%, 8%, 7%, 5%, 4%, 3%, or 2 as assessed by the Anti-Stick Screening Method. % Residual dirt or exudate may be left on the skin surface. Skin, whether alone or in lotion, that has not been treated with anti-sticking agents but nevertheless has undergone the above method may serve as a negative control. Typically, untreated skin results in about 30-35% residual soil or exudate remaining on the skin surface.

  Conventional substrates containing both aqueous and emulsion lotions may deliver anti-stick performance in the range of about 15-30% residual soil or exudate in the above method. This level of performance has been found to be insufficient to deliver an anti-stick benefit that can be perceived by consumers.

  The lotion of the present invention may comprise at least about 0.05% by weight anti-sticking agent and at least about 0.01% performance enhancing agent. The lotion may contain up to about 50% by weight anti-sticking agent and up to about 3% performance enhancing agent. The lotion is about 0.05%, 0.1%, 0.5%, 1%, 2%, 4%, or 5% to about 8%, 10% by weight of the lotion composition. %, 20 wt%, 25 wt%, or 50 wt% anti-sticking agent may be included. Lotion is about 0.05%, 0.1%, 0.15%, 0.18%, 0.2%, 0.3%, 0.4%, or 0.5% to about 0.5% of the lotion composition Performance enhancers may be included at concentrations of 1%, 2%, or 3% by weight.

  Lotions containing anti-sticking agents and performance enhancing agents, as described herein, contain less than about 10% residual soil or exudates as measured by the Anti-Stick Screening Method. May be effective for leaving on skin. Such lotions may leave residual soil or exudate remaining on the skin of less than about 2%, 3%, 4%, 5%, 7%, 8%, or 10%. A lotion composition containing an anti-sticking agent at a concentration of about 2% and a performance enhancing agent at a concentration of about 0.18% may leave less than about 10% residual soil or exudate on the skin. A lotion composition comprising an anti-sticking agent at a concentration of about 2% and a performance enhancer at a concentration of about 0.18% may leave less than about 8% residual soil or exudate on the skin. A lotion composition comprising an anti-sticking agent at a concentration of about 5% and a performance enhancing agent at a concentration of about 0.18% may leave less than about 4% residual soil or exudate on the skin. The lotion comprising the anti-sticking agent and the performance enhancing agent may be in contact with or associated with the substrate, as described herein. Lotion wipes may also be effective in leaving about 10%, 8%, 7%, 5%, 4%, 3%, or 2% residual soil or exudate on the skin.

For water-soluble anti-sticking agents:
Non-polymeric anti-sticking agents such as glycerol and related polyols such as sorbitol, maltitol, xylitol, pentaerythitol, sucrose, glucose, maltose, maltotriose, maltodextrin, maltopentose, maltohexose (Maltohexose), and isomaltulose, ethylene glycol, propylene glycol, butylene glycol, etc.
-Polymeric anti-sticking agents including polyethylene glycol, polypropylene glycol, polybutylene glycol, polyglycerol, or block copolymers comprising ethylene oxide and propylene oxide, mixtures thereof, etc.
-Alkoxylated polyol compounds,
-Phosphate compounds, such as monoalkyl phosphates and dialkyl phosphates,
And combinations of the above, but are not limited thereto.

Non-polymeric anti-sticking agent:
Non-polymeric anti-sticking agents such as those described above may provide anti-sticking benefits. Non-polymeric anti-sticking agents may be required at relatively high concentrations in the composition as compared to polymeric anti-sticking agents.

Polymer anti-sticking agent:
Polymeric anti-sticking agents, including mixtures thereof, including polyethylene glycol, polypropylene glycol, polybutylene glycol, polyglycerol, or block copolymers comprising ethylene oxide and propylene oxide have been found to be useful as anti-sticking agents. ing. Commercially available examples of polymeric anti-sticking agents include Carbowax ™ and Polyox (such as those available from The Dow Chemical Company, Midland, Michigan) Trademark series, and Pluronic (TM), Pluronic (TM) R, Tetronic as available from BASF Corporation of Florham Park, NJ (Trademark) and Tetronic (trademark) R surfactant series. In one embodiment, a lotion comprising Carbowax ™ 400 at a concentration of about 5% by weight and a performance enhancer at a concentration of about 0.18% by weight contains less than about 9% residual soil or Exudates may remain on the skin. In another embodiment, a lotion comprising Pluronic ™, eg, Pluronic ™ F68 at a concentration of about 2 wt% and a performance enhancer at a concentration of about 0.18 wt%, Less than about 10% of residual soil or discharge may be left on the skin. In yet another embodiment, a lotion comprising Pluronic ™, eg, Pluronic ™ F68 at a concentration of about 5% by weight and a performance enhancer at a concentration of about 0.18% by weight is , May leave less than about 4% residual soil or discharge on the skin.

Alkoxylated polyol compounds:
Alkoxylated polyol compounds have also been found to deliver anti-stick benefits. The alkoxylated polyol compounds useful in the present invention comprise a central polyol moiety that contains at least three hydroxyl groups, at least one of which is alkoxylated. The alkoxyl group constitutes polyoxyethylene, polyoxypropylene, polyglycerol, and / or mixtures thereof. The average total degree of alkoxylation may be from about 1 to about 100. FIG. 1 is a diagram of a general structure in which tris-alkoxylated glycerol may match, where:
A ₁ , A ₂ , and A ₃ are hydrogen, methyl, or any mixture thereof,
D ₁ , D ₂ , and D ₃ are polyoxyethylene, polyoxypropylene, or a combination thereof as illustrated in FIG. In one embodiment, p may average 4.2 and e may average 13.4.

The alkoxylated polyol compounds useful in the present invention may further have at least one alkoxy moiety constituting at least one anionic capping group, as described in PCT International Publication No. WO2005 / 063847. In one embodiment,
A ₁ is hydrogen or methyl;
A ₂ and A ₃ are sulfate (SO ₃ ⁻ ),
D ₁ , D ₂ , and D ₃ are polyoxyethylene, polyoxypropylene, or a combination thereof as illustrated in FIG. In one embodiment, p may average 4.2 and e may average 13.4.

  In another embodiment, the lotion may comprise tris-alkoxylated glyceryl bis-sulfate at a concentration of about 2% by weight and a performance enhancer at a concentration of about 0.18% by weight and less than about 8% by weight. Residual stains or discharges may remain on the skin.

  It can be appreciated by those skilled in the art that any suitable polyol compound can function as the central polyol moiety and that any number of one or more alkoxyl groups and any number of anionic capping groups can be used. It can also be appreciated that the alkoxyl groups can be of any type described and need not be the same. It can also be appreciated that the anionic capping groups can be of any type described and need not be the same.

Phosphate compounds The phosphate compounds may include monoalkyl phosphates and dialkyl phosphates.

  The monoalkyl phosphate may have a structural formula as illustrated in FIG. 3, where R represents a saturated or unsaturated hydrocarbon group having an average of 8 to 22 carbon atoms, and x is Represents a number from 0 to 20 and each of Y and Z represents hydrogen, alkali metal, ammonium, or alkanolamine.

  The dialkyl phosphate may have a structural formula as illustrated in FIG. 4, where R represents a saturated or unsaturated hydrocarbon group having an average of 8 to 22 carbon atoms, and x is 0 Represents a number of ~ 20 and each of Y and Z represents hydrogen, alkali metal, ammonium or alkanolamine.

  A saturated or unsaturated hydrocarbon group having an average of 8 to 22 carbon atoms can be a straight chain, branched chain, or alicyclic hydrocarbon, as is known to those skilled in the art. In certain embodiments, the saturated or unsaturated hydrocarbon group may have an average of 10 to 18 carbon atoms.

  Alkali metals and amines include lithium, sodium, potassium, dimethylmonoethanolamine, methyldiethanolamine, trimethylamine, triethylamine, dibutylamine, butyldimethylamine, monoethanolamine, diethanolamine, triethanolamine, isopropyldimethylamine, and isopropylethanolamine However, it is not limited to these.

Optional lotion ingredients Additional ingredients may be added to the lotion as desired to create a lotion composition. The composition may generally comprise any of the following ingredients: emollients, surfactants, preservatives, or combinations of preservative compounds that cooperate as preservative systems, or other adjuvant ingredients. It should be noted that some component compounds may have multiple functions and that not all compounds are necessarily present in the composition. The composition may also be an aqueous solution or an emulsion. The pH of the composition may be about pH 3, 4, or 5 to about pH 7, 7.5, or 8.

  Examples of lotions and lotion compositions that may be used may be found in the Examples section as Examples 1-12.

Emollients Emollients improve (1) lubrication and thus improve the slip of the substrate on the skin by reducing skin peeling, (2) residues (eg fecal residues or (3) hydrates the skin and thus reduces its dryness and irritation while hydrating the skin (soft urine residue or menstrual blood or menstrual blood), thus reducing its dryness and irritation And (4) when the emollient is deposited on the skin and remains as a thin protective layer on the surface, it may protect the skin from subsequent irritation (eg caused by friction of the absorbent article). is there.

  Emollients include silicone oils, functionalized silicone oils, hydrocarbon oils, aliphatic alcohols, aliphatic alcohol ethers, fatty acids, monobasic and / or dibasic and / or tribasic and / or polybasic carboxylic acids. Mention may be made of esters with polyhydric and polyhydric alcohols, polyoxyethylene, polyoxypropylene, mixtures of polyoxyethylene and polyoxypropylene ethers of aliphatic alcohols, and mixtures thereof. The emollient may be either saturated or unsaturated, may have an aliphatic nature, and may be linear or branched, or an alicyclic or aromatic ring. You may contain.

  A useful mixture of emollients is known as ABIL CARE ™ 85 (available from Degussa Care Specialties, Hopewell, VA). Caprylic acid capric acid triglyceride in combination with PPG-16 / 16PEG / PPG-16 / 16 dimethicone.

  The emollient, when present, is used in the present invention at about 0.5%, 1%, or 4% to about 0.001%, 0.01%, or 0.02% by weight. Also good. Without being bound by theory, low concentrations of emollients may reduce the tendency to form a greasy or oily layer of emollient on the skin, which may be undesirable for consumers. Because it is, it is considered desirable.

Surfactant The surfactant can be an individual surfactant or a mixture of surfactants. The surfactant may be a polymeric surfactant or a non-polymeric surfactant. A surfactant may be employed as an emulsifier. When present, the surfactant is present in an amount effective to emulsify the emollient and any other water-insoluble oil that may be present in the composition, for example, about 0.5% by weight, 1% by weight. %, Or from 4 wt% to about 0.001 wt%, 0.01 wt%, or 0.02 wt% (based on the weight of surfactant relative to the weight of the composition). Good.

  The composition may include one or more surfactants. The surfactant or combination of surfactants may be mild, which provides sufficient cleansing or cleansing benefits, but over-drys or otherwise inhibits the skin. Or it means no damage.

  A wide variety of surfactants are useful herein, as well as anionic surfactants, nonionic surfactants, cationic surfactants, amphoteric surfactants, bipolar surfactants, and mixtures thereof Those selected from the group consisting of:

  A wide variety of anionic surfactants are useful herein. Non-limiting examples of anionic surfactants include those selected from the group consisting of sarcosinate, sulfate, sulfonate, isethionate, taurate, phosphate, lactylate, glutamate, and mixtures thereof. Among the isethionates, alkoxy isethionates are useful, and among the sulfates, alkyl and alkyl ether sulfates are useful. Other anionic materials useful herein are typically soaps of fatty acids having from about 8 to about 24 carbon atoms (ie, alkali metal or amine salts such as sodium, potassium, or triethanolamine) Salt).

  Nonionic surfactants useful herein include alkyl glucosides, alkyl polyglucosides, polyhydroxy fatty acid amides, alkoxylated fatty acid esters, alkoxylated fatty alcohol ethers, sucrose esters, amine oxides, and mixtures thereof. Although selected from the group which consists of, it is not limited to these.

  Suitable amphoteric or bipolar surfactants for use in the compositions herein include those known for use in hair care or other personal care cleansing. Suitable amphoteric surfactants for use in the compositions of the present invention include those well known in the art and widely described as derivatives of aliphatic secondary and tertiary amines. Among them, aliphatic radicals can be straight or branched and one of the aliphatic substituents contains from about 8 to about 18 carbon atoms, and one is carboxy, Contains anionic water solubilizing groups such as sulfonates, sulfates, phosphates, or phosphonates. Useful amphoteric surfactants include, but are not limited to, the group consisting of cocoamphoacetate, cocoamphodiacetate, lauroamphoacetate, lauroamphodiacetate, and mixtures thereof.

  Suitable dipolar surfactants for use herein include surfactants widely described as derivatives of aliphatic quaternary ammonium compounds, phosphonium compounds and sulfonium compounds, among which aliphatic The radical can be straight or branched and one of the aliphatic substituents contains from about 8 to about 18 carbon atoms and one is carboxy, sulfonate, sulfate, Contains anionic groups such as phosphates or phosphonates. Useful zwitterionic detersive surfactants are betaines, amphoacetates, and sulfobetaines such as cocoamidopropylbetaine, sodium lauryllamphoacetate, and cocoamidopropylhydroxysultain.

Preservatives Controlling the growth of microorganisms can be beneficial in aqueous products such as lotion compositions intended to be applied to a substrate in forming a wipe. The lotion composition may comprise a preservative or a combination of preservatives that cooperate as a preservative system. Preservatives and preservative systems are used interchangeably in this text to indicate only one or a combination of preservative compounds. Preservatives reduce microbial growth and thus allow a longer shelf life for the substrate package (open or unopened), as well as reduce microbial growth when transferred to the skin during the wiping process. It may be understood as a chemical or natural compound or combination of compounds that creates the environment.

  The antibacterial spectrum of preservatives may include bacteria, molds and yeasts. Each of these microorganisms may be killed by preservatives. Another mechanism of action to be considered may be to reduce the growth rate of microorganisms without aggressive killing. However, both effects result in a dramatic decrease in the microbial population.

  Materials useful as preservatives include, but are not limited to: methylol compounds, iodopropynyl compounds, monocyclic aromatic alcohols, paraben compounds, chelating agents such as ethylenediaminetetraacetic acid, and combinations thereof.

  In one embodiment, the preservative system may include a methylol compound or equivalent thereof, an iodopropynyl compound, and mixtures thereof. Methylol compounds may release low concentrations of formaldehyde when in aqueous solution with effective preservative activity. Exemplary methylol compounds include diazolidinyl urea (GERMALL® II, such as that available from International Specialty Products, Wayne, NJ), N- [1. , 3-bis (hydroxymethyl) -2,5-dioxo-4-imidazolidinyl] -N, N′-bis (hydroxymethyl) urea, imidourea (International Specialty Products of Wayne, NJ) GERMALL® 115), 1,1-methylenebis [3- [3- (hydroxymethyl) -2,5-dioxo-4-imidazolidinyl] urea], 1 , 3-Dimethylol-5,5-dimethylhy Dantoin (DMDMH), sodium hydroxymethylglycinate (SUTTOCIDE® A as available from International Specialty Products of Wayne, NJ), and anhydrous glyceride Syndimethylol (GADM) can be mentioned, but is not limited thereto. The methylol compound can be used at a concentration of about 0.025% to about 0.50% by weight. In another embodiment, the concentration may be about 0.075% by weight. An iodopropynyl compound may provide antifungal activity. An exemplary material may be iodopropynyl butyl carbamate, such as is available as NIPACIDE ™ IPBC from Clariant UK, Ltd., Leeds, UK. Another exemplary material may be 3-iodo-2-propynyl butyl carbamate. The iodopropynyl compound can be effectively used at a concentration of about 0.001% to about 0.05% by weight. The concentration may be about 0.009% by weight. This type of preservative system may comprise a blend of methylol compounds at a concentration of about 0.075% by weight and an iodopropynyl compound at a concentration of about 0.009% by weight.

  In another embodiment, the preservative system may include a monocyclic aromatic alcohol (eg, benzyl alcohol). This type of material may have effective antimicrobial activity. Benzyl alcohol is available from Symrise, Inc. of Teterboro, NJ.

  In another embodiment, the preservative may comprise at least one paraben antibacterial agent. The preservative may be a paraben antibacterial agent selected from the group consisting of methyl paraben, ethyl paraben, propyl paraben, butyl paraben, isobutyl paraben, or combinations thereof. The total concentration of the paraben antibacterial agent may be less than about 0.3%, 0.5%, or 1% by weight. The minimum amount of paraben antibacterial agent may be any amount sufficient to obtain the desired preservative of the composition, for example, greater than about 0.001%.

  In another embodiment, the acidic compound used in an amount sufficient to lower the pH of the lotion composition (eg, a pH of less than about 5) is synergistic as a preservative or for other preservative ingredients. It may be useful as an agent.

  In another embodiment, chelating agents such as ethylenediaminetetraacetic acid and its salts may also be used as synergists for other preservative components in the preservative system.

Adjunct ingredients The lotion composition may optionally include other adjunct ingredients. Possible adjuvant ingredients include, but are not limited to, a wide range such as perfumes and fragrances, texturizers, colorants, soothing agents, and medically active ingredients such as healing actives and skin protectants. It may be selected from additional components.

Merchandise In one embodiment, merchandise may be provided. The merchandise may include a container as described herein and at least one substrate as described herein.

  Useful containers include PET tubs, flow wrap pouches, bags with cuts for cleansing mitts in individual packs, and other packaging known to those skilled in the art as suitable for nonwoven articles. However, it is not limited to these. Furthermore, the containers may also be manufactured to facilitate removal of individual cleansing substrates.

  The container may be made from any suitable material or materials and can be manufactured in any suitable manner. For example, the container can be made from polystyrene, polypropylene, PET, POET, polyethylene, polyester, polyvinyl alcohol, or the like. The container may also be made from a mixture of the above materials. The container may be manufactured, for example, by a vacuum molding process or an injection molding process, or any suitable process.

  Additions to the container and any additional optional components of the container, including but not limited to the container body, lid, container mechanism (including but not limited to lid attachments, hinges, zippers, securing means, etc.) US Pat. Nos. 451,279; 437,686; 443,508; 443,451; 421,901; 421,902; 416 No. 414,637; No. 445,329; US Pat. No. 3,982,659; No. 3,967,756; No. 3,986,479; No. 994,417; No. 6,269,970; No. 5,785,179; No. 5,366,104; No. 5,322,178; No. 5,050,737; No. 4,971,220; 6,296,144; 6,315,114; 4,840,270; 4,471,881; 5,647,506; 6,401, No. 6,269,969; No. 6,412,634; No. 5,791,465; No. 6,092,690; US Patent Application Publication No. 2002/0064323 (Chin), published May 30, 2002); and PCT International Patent Publication WO00 / 27268 (published May 18, 2000 and assigned to The Procter & Gamble Company); PCT International Publication Patent WO02 / 14172 (published on February 21, 2002 and assigned to The Procter & Gamble Company); and PCT International Patent Publication WO99 / 55213 ( 999 November 4, the public, can be found in the Procter & Gamble Company, assigned to (The Procter & Gamble Company)).

Anti-Stick Screening Method
This method is used to assess the adhesion of dirt or exudates to the skin by quantifying the percentage of residual artificial glue-like stool (“ABM”) left on the treated skin surface. Also good. ABM, like the actual infant BM, cannot aggregate, resulting in some of the ABM remaining on the skin surface and some of the ABM being removed. The more effective the lotion containing anti-sticking agent or anti-sticking agent and performance enhancer, the lower the percentage of residual ABM on the skin surface.

  At least 8 healthy adults participate in a single screening test. Each of the sensory testers completes a four-day washout period, during which time they clean their forearms, The Procter and Gamble Company, Cincinnati, Ohio Use Olay® unscented moisturizing soap as circulated by Sensory testers should stop using any topical products such as ointments, creams, or lotions on their forearms during this washout period and also on the day of the screening test. On the day of the test, the arms of the sensory examiner are inspected to ensure that they are free of cuts, abrasions, and rashes. If any skin abnormality is present, the sensory tester cannot participate.

  Templates and tapered markers are used to mark up to 10 3 cm × 3 cm sites on the palmar forearm, ie up to 10 sites per sensory tester. All but one of these sites are treated with anti-sticking agents or lotions containing anti-sticking agents. The remaining sites are not subjected to anti-sticking treatment, i.e. serve as negative controls. Various treatment locations, including untreated sites, may be randomized among the sites on each sensory tester. The test begins at the site closest to the elbow on the left arm, and once the test for each site is completed, to the site closest to the wrist on the left arm, then to the site closest to the elbow on the right arm, and finally to the right arm Proceed to the site closest to the upper wrist. The test for each site requires approximately 4 minutes and requires a total time of approximately 40 minutes per sensory tester.

For each site to be treated, a 1 μL / cm ² or 9 μL / lotion site containing anti-sticking agent or anti-sticking agent and performance enhancing agent is applied to the center of the site using a standard or volumetric flow pipette. The adhesive or lotion is then applied using a powderless finger sac of catalog number 56613-413 as available from VWR Scientific, West Chester, Pa. Place the sac on top of the drop of agent or lotion and gently rub the finger sack across the skin surface using several left and right and up and down motions for a total elapsed time of 10-15 seconds. (Its boundary is defined by a mark made using the template). When examining a site from an oblique angle, the person performing the test must ensure that a uniform coating is formed over the entire area of the site. The coating is left exposed to air and left untouched for approximately 1 minute before proceeding to further processing.

  Catalog number BD-309628, such as that available from VWR Scientific, West Chester, Pennsylvania, is a 1 mL syringe filled with room temperature ABM and free of air bubbles. Installed on a tared four-place analytical balance. The weight is recorded. By keeping the syringe with ABM moderately close to the skin surface, above the center of the test site on the forearm, and by watching the plunger move and gradually move on the syringe, Approximately 0.2 mL of ABM is dispensed onto the skin. ABM needs to form a dense bulge that is reasonably uniform in the center of the test site. The syringe is reweighed on an analytical balance and the weight is recorded. The amount of ABM delivered to the forearm is calculated by subtracting the first to second weights.

  Catalog No. 12578-201, 4 cm x 4 cm weighing paper, such as that available from VWR Scientific, West Chester, Pennsylvania, was tared on a 4-digit chemical balance and the forearm Centered above the bulge of the ABM on the test site and gently lowered onto the ABM using forceps. The weigh paper should not be touched with the fingertips because it may transfer oil onto its surface. Next, a 500 g bottle shaped weight that exerts a downward force of approximately 3.4 kPa (0.5 psi), for example, available from VWR Scientific, West Chester, Pa. A catalog number 12766-518 is placed above the weighing paper so that the bulge of the ABM under the weighing paper is approximately centered under the weight. The weight may be gently held in place or balanced on the forearm by a sensory tester for 30 seconds. After 30 seconds, two fingers are gently placed on both sides of the weighing paper to hold it in place and the 500 g weight is slowly lifted. Using one forceps, the weighing paper is slowly and gently peeled off the test site. Forceps are installed in the lower right corner of the weighing paper, and the weighing paper is slowly peeled upward toward the upper left corner of the weighing paper. It takes approximately 1 to 2 seconds to remove the weighing paper. Once removed, the weighed paper is placed back on the weighed chemical balance and the weight is recorded to determine the amount of ABM removed.

  The above process is repeated until all sites per sensory tester have been tested, i.e. application of lotion containing anti-sticking agent or anti-sticking agent and performance improver, application of ABM, application of weighing paper, weighting The process consisting of application and removal of the weighing paper is repeated. For untreated controls, application of the agent or lotion is omitted, and ABM is applied directly to the skin site.

An example of a summary table for collecting various weight measurements and calculating the percentage of residual ABM left on the arm is as follows:

In this:
-Sub refers to the subject number, which is at least 101-108 and ideally 101-110, i.e. the above plan is 8-10 to handle all sensory testers. Repeated times.
-Site refers to the location of the arm, starting from the left arm near the elbow (Site 1) and progressing to the right arm near the wrist (Site 10).
-Process (Trtmnt) refers to the symbol of the applied process, typically the letters AJ.
-Syringe refers to the initial weight of the syringe containing the ABM.
-Syringe After refers to the final weight of the syringe containing the ABM once approximately 0.2 mL of ABM has been dispensed onto the treatment site.
-Applied ABM (ABM Applied) is the calculated value obtained from the equation, Syringe-Syringe After = Applied ABM (ABM Applied).
-ABM Removed refers to the weight of ABM obtained on the tared weighed paper after the weighed paper has been peeled from the treated site.
-% ABM Arm is calculated from the equation, ((ABM Applied)-ABM Removed) / ABM Applied) x 100 Value. This is a measure of the percentage (%) of residual ABM on the treated surface.

  The average value and standard error of the average value (“SEM”) for each treatment for all sensory testers, eg 101-110, eg AJ, is calculated and graphed.

  When the method is run correctly, the untreated control may yield approximately 30% to 35% residual ABM.

  The method may also be used to evaluate lotion compositions squeezed from commercial wipes. The squeezed lotion composition inserts the entire stack of unexpired commercial product wipes into a pre-cleaned press that can exert a downward force of about 552 kPa (80 psi) on the stack. It is prepared by. Ideally, the lower plate of the press may have a groove in which the compressed lotion may be collected, and the compressed lotion may flow through it into a clean storage container Contains holes. An example of a suitable storage container is catalog number 83008-666, such as is available from VWR Scientific, West Chester, Pennsylvania. All pressed lotions are stored at room temperature before use.

  The day before testing, 10 mL of each anti-sticking agent or lotion composition is made of glass such as catalog number 66022-060 as available from VWR Scientific, West Chester, Pa. Moved into scintillation vial. Each vial is labeled with a process symbol, eg, AJ. On the day of inspection, anti-sticking agent or lotion composition is removed from the scintillation vial with a standard or volumetric flow pipette and applied to each treatment site as described in the method. By having various treatments in the scintillation vials, it is very easy to reposition the vials among sensory testers to accommodate a randomization scheme for testing.

  To ensure reproducible results, the Anti-Stick Screening Method needs to be performed at room temperature of 21 ° C. ± 2 ° C. and at 30-50% relative humidity. .

Preparation of Artificial Pasty Bowel Movement (ABM) The following equipment is required:
-An analytical balance with an accuracy of ± 0.001 g-a homogenizer capable of stirring until the components are homogeneous, eg available from Ika-Werke GmbH and Co. KG, Staufen, Germany As such, Ika Labortechnik ™ T25 basic or equivalent.
A homogenizer probe to be used with the homogenizer, for example catalog number S25N 25F as available from Ika-Werke GmbH and Co. KG of Staufen, Germany.

The following reagents are required:
-Feclone (TM) powder # 4, available from SiliClone Studio, Valley Forge, PA as catalog number Feclone BFPS-4.
-Feclone (TM) Powder # 6, available as Catalog Number BFPS-6 from SiliClone Studio, Valley Forge, Pa.
-Feclone ™ Powder # 7, available as Catalog Number BFPS-7 from SiliClone Studio, Valley Forge, Pa.
-Carbopol ™ 981, available from BF Goodrich, Cleveland, Ohio.
-Deionized water

The following amounts of the above reagents are required:

The procedure for preparing ABM consists of the following steps:
A. Preparation of Carbopol ™ solution 1. Weigh 78.78 g ± 0.01 g of deionized water into a 250 mL beaker.
Weigh 2.0.900 g ± 0.001 g of Carbopol ™ on weighing paper.
3. Place the beaker on a magnetic stirrer and set the speed to 400 rpm.
4). Slowly add Carbopol ™ powder to water over a length of about 5 minutes. Slowly increase the stirring speed to 600 rpm while adding Carbopol ™.
5. Once Carbopol ™ powder has been added to the water, cover the beaker and continue mixing at 600 rpm for 15 minutes. The Carbopol (TM) powder must be completely dispersed, i.e. a clear gel without any agglomerates.
6). The hot plate is operated at 150 ° C. Place the Carbopol ™ solution on a hot plate and continue mixing at 600 rpm until the solution is heated to 81-83 ° C.
B. Preparation of ABM mixture Weigh 6.600 g ± 0.01 g of each of Feclone powders # 4, # 6, and # 7 into a beaker and mix well.
2. Using a T25 basic or equivalent homogenizer with a homogenizer probe, stir the Carbopol ™ solution at 8000 rpm for about 30 seconds before proceeding to step 3.
3. Slowly add about a quarter of the total volume of the Feclone ™ powder mixture to the stirred Carbopol ™ solution at a time. Ensure that the Feclone ™ powder mixture passes through the homogenizer probe during the addition, ie, completely mixes into the pasty composition that is forming. If necessary, a spatula is used to facilitate incorporation of the Feclone ™ powder mixture into the composition.
4). After all of the Feclone ™ powder mixture has been added, continue mixing with the homogenizer at 8000 rpm for an additional 5 minutes while using a spatula to push the paste-like composition toward the homogenizer probe. The composition should be thoroughly mixed and appear homogeneous.

  The completed ABM may be placed in a container such as catalog number 14233-954 as available from VWR Scientific, West Chester, Pa. And 30 It may be stored in the refrigerator for up to days. After 30 days, a new sample needs to be prepared for further experiments. The container must be tightly sealed to avoid drying from the ABM.

  Prior to using the ABM in the Anti-Stick Screening Method, the ABM must be removed from the refrigerator and adjusted to room temperature. A simple way to accomplish this is to fill a 10 mL syringe, eg, catalog number BD301604, such as that available from VWR Scientific, West Chester, Pa., With cold ABM and then syringe. Is allowed to equilibrate to room temperature on a countertop. Equilibration typically takes about 15 minutes. The 10 mL syringe can then be used to fill a 1 mL syringe as described in the Anti-Stick Screening Method.

The lotion compositions of Examples 1-12 were prepared as described above using a substrate such as Fibrella 3160, 40% Bis, as available from Suominen, Tampere, Finland. Contacted with a 58 g / m ² non-woven comprising a blend of course fiber and 60% polypropylene fiber, or any other substrate deemed suitable for use.

Δドイツのノルダーシュテット（Norderstedt）のシュルケ・アンド・マイヤー社（Schuelke and Mayr GmbH）から入手可能である。 In the examples, “QS” refers herein to the “suitable amount” and is the percentage of water added to the composition sufficient to bring the total composition to 100%.

Δ Available from Schuelke and Mayr GmbH of Norderstedt, Germany.

  The dimensions and values disclosed herein are not to be understood as being strictly limited to the exact numerical values recited. Instead, unless otherwise specified, each such dimension is intended to mean both the recited value and a functionally equivalent range surrounding that value. For example, a dimension disclosed as “40 mm” is intended to mean “about 40 mm”.

  All documents cited in the “Best Mode for Carrying Out the Invention” of the present invention are incorporated herein by reference in their relevant parts, and any citation of any document is a prior art to the present invention. It should not be construed as an admission that it is. To the extent that any meaning or definition of a term in this specification conflicts with any meaning or definition of a term in a document incorporated by reference, the meaning or definition given to that term in this specification applies. Shall.

  While particular embodiments of the present invention have been illustrated and described, it would be obvious to those skilled in the art that various other changes and modifications can be made without departing from the spirit and scope of the invention. Accordingly, it is intended to cover in the appended claims all such changes and modifications that are within the scope of this invention.

An example of a general structure where tris-alkoxylated glycerol may be matched. An example of a general structure in which the combination of polyoxyethylene and polyoxypropylene may match. An example of a general structure of monoalkyl phosphate. An example of a general structure of dialkyl phosphate.

Claims (14)

a. A substrate;
b. A lotion comprising an anti-sticking agent and a performance enhancer, wherein the lotion is in contact with the substrate;
Including lotion wipes.   The wipe of claim 1, wherein the lotion is effective in that residual soil or exudate remains below about 10% by weight as measured by the Anti-Stick Screening Method.   The wipe according to claim 1 or 2, wherein the lotion comprises about 50 wt% or less of the anti-sticking agent.   The wipe according to any one of claims 1 to 3, wherein the lotion comprises about 3 wt% or less of the performance enhancer.   The wiping article according to any one of claims 1 to 4, wherein the anti-sticking agent is water-soluble.   6. The anti-sticking agent according to any one of claims 1 to 5, wherein the anti-sticking agent is selected from the group consisting of non-polymeric anti-sticking agents, polymeric anti-sticking agents, alkoxylated polyols, phosphate compounds, and combinations thereof. Wiping products.   The non-polymeric anti-sticking agent is glycerol, sorbitol, maltitol, xylitol, pentaerythitol, sucrose, glucose, maltose, maltotriose, maltodextrin, maltopentose, maltohexose, isoto The wipe according to claim 6, selected from the group consisting of maltulose, ethylene glycol, propylene glycol, butylene glycol, and combinations thereof.   The wipe according to claim 6, wherein the polymeric anti-sticking agent is selected from the group consisting of polyethylene glycol, polypropylene glycol, polybutylene glycol, polyglycerol, block copolymers comprising ethylene oxide and propylene oxide, and combinations thereof. .   The wipe according to claim 6, wherein the alkoxylated polyol comprises a central polyol moiety comprising at least three hydroxyl groups, at least one of the hydroxyl groups being alkoxylated to form an alkoxyl group.   10. The wipe according to claim 9, wherein the alkoxyl group comprises a material selected from the group consisting of polyoxyethylene, polyoxypropylene, polyglycerol, or mixtures thereof.   The wipe according to claim 9, wherein the alkoxyl group constitutes at least one anionic capping group.   The wipe according to claim 6, wherein the phosphate compound is selected from the group consisting of monoalkyl phosphates, dialkyl phosphates, and combinations thereof.   The wipe according to any one of claims 1 to 12, wherein the performance improver comprises a substance selected from the group consisting of a film forming agent, an adhesion aid, a rheology modifier, and combinations thereof.   The wipe according to claim 13, wherein the performance improver is a rheology modifier.

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