JP2009007307A - Cosmetic or skin preparation for external use - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a cosmetic or a skin preparation for external use comprising chatsargan oil that is useful for ameliorating rough skin by allergy or the like. <P>SOLUTION: The cosmetic or the skin preparation for external use comprises chatsargan oil extracted from a fruit of chatsargan. The examples of the cosmetics and the skin preparations for external use include a lotion, milky lotion, emulsion, cream, gelling agent, ointment, cosmetic oil, soap, liquid soap, shampoo, hair rinse, hair conditioner, hair-dressing agent and the like. <P>COPYRIGHT: (C)2009,JPO&INPIT

Description

  The present invention relates to a cosmetic or skin external preparation containing an oil derived from chachargan fruit.

  In the world, three types of chargans are known: Hippophae rhamnoides, Hippophae Salicifolia Don, and Hippophae thibetana Sch of the family Gleidae (Elaeagnaceae). Of these, the most widely inhabited is Hippophae rhhamnoides. Chachargan is mainly cultivated in Mongolia.

  Chachargan has a male tree and a female tree, and when the flower pollinates, yellow-green fruits are formed. This chachargan fruit contains various vitamins, especially a large amount of vitamin C. In addition, a wide variety of amino acids such as aspartic acid is contained. Furthermore, many oil components are contained in the pulp, pericarp and seed, and it is said that the content of carotenes is particularly high (Non-patent Document 1). And in Obusu County, Mongolia, Chachargan has long been widely used for food and treatment (Non-patent Document 2).

HEADLINE NEWS March 15, 2006 (http://joyo-net.com/kako/2006/honbun060315.html) Chachargan's Home Country-Obus 2007.04.15 Updated (http://www.geocities.jp/sato032/cyacya.html)

  The present inventor has paid attention to the fact that Chachargan has been heavily used as a folk medicine in Mongolia, and has verified its therapeutic effect. As a result, it has been found that rough skin caused by allergies and the like is improved by using an external preparation containing an oil component derived from chachargan fruit (hereinafter referred to as “chachargan oil”). From this, the present inventor has eagerly studied to provide a cosmetic or external preparation for skin containing chachargan oil, and completed the present invention.

  That is, this invention relates to the cosmetics or the skin external preparation characterized by containing a chachargan oil. The cosmetics and the external preparation for skin have different purposes of use, but are the same as products.

  Examples of cosmetics or external preparations for skin include lotions, emulsions or emulsions, creams, gels, ointments, cosmetic oils, soaps, liquid soaps, shampoos, hair rinses, hair conditioners and hair styling agents.

  Examples of the cosmetics or external preparations for skin include (1) lotion, and the content of chachargan oil is 0.0001 to 1.0000% by weight of the total amount of the lotion, (2) emulsion or An emulsion having a chachargan oil content of 0.0001 to 20.000% by weight of the total amount of the emulsion or emulsion, and (3) a cream, and the chachargan oil content is the total amount of the cream. And 0.0001 to 30.000% by weight of the above.

  The cosmetic or external preparation for skin according to the present invention may contain only chachargan oil as the oil component.

  The present invention provides cosmetics and external preparations for skin that can be used by people with sensitive skin.

  Moreover, rough skin caused by allergies and the like is improved by using the cosmetic or external preparation for skin according to the present invention.

  Hereinafter, the present invention will be described based on the best mode for carrying out the invention.

  The chachargan oil used in the present invention is derived from the fruit of chachargan. According to one theory, it is said that the chachargan fruit contains about 14 to 27% of oil components, about 17 to 33% of pericarp, and about 12 to 13% of oil components in seeds. Although the composition of the oil component is not completely the same in the flesh, pericarp, and seed, in the present invention, any of oil derived from the flesh, oil derived from the pericarp, and oil derived from the seed may be used. it can. Moreover, the mixture of those oils may be sufficient.

  Table 1 shows an analysis example (data of 5 examples) of constituent fatty acids of triglyceride of chachargan oil. This is an analysis of constituent fatty acids without separating only triglycerides from oil components derived from skin, pulp and seeds. Unidentified includes components derived from oily components other than triglycerides. In addition, it is thought that triglyceride content of chachargan oil is 90 or more%. As shown in Table 1, it can be seen that palmitoleic acid (9-hexadecenoic acid) and palmitic acid (hexadecanoic acid) are extremely abundant as the constituent fatty acids of triglycerides in chachargan oil.

  Separation and purification of chachargan oil from chachargan fruit is performed, for example, as follows. That is, first, the fruit of chachargan is squeezed and divided into straw and liquid. The liquid is then divided into an oil and a water-soluble part (fruit juice). This oil separation step is performed, for example, by centrifugation. Further, for the purpose of promoting oil separation, a demulsifier (emulsification breaker) may be added before centrifugation. These steps are usually performed at room temperature. When the oil is exposed to high temperatures by performing a process such as steaming before pressing, the fatty acids in the fats and oils are oxidized and the fatty acid composition in the triglycerides changes, and the feel, performance, and efficacy of cosmetics and skin external preparations are changed. It is because it may affect.

  The cosmetics or external preparations for skin, which are the subject of the present invention, include all those used as cosmetics or external preparations for skin regardless of the dosage form and specific use. The concept of cosmetics includes not only cosmetics but also quasi drugs and designated quasi drugs. Examples include lotions, emulsions or emulsions, creams, gels, ointments, cosmetic oils, soaps, liquid soaps, shampoos, hair rinses, hair conditioners, hair conditioners, various make-up cosmetics, and the like.

  The blending amount of chachargan oil in the cosmetic or external preparation for skin according to the present invention is not particularly limited, and may be blended in accordance with regulations such as the Pharmaceutical Affairs Law and within a range that can be formulated. it can.

  When the cosmetic or skin external preparation is a lotion, the chachargan oil content is preferably 0.0001 to 1.0000% by weight, and 0.001 to 0.800% by weight of the total amount of the lotion. More preferably, it is 0.005 to 0.500% by weight, still more preferably 0.010 to 0.300% by weight. In the case of an emulsion or emulsion, the content of chachargan oil is preferably 0.0001 to 20.000% by weight of the total amount of the emulsion or emulsion, and is 0.001 to 15,000% by weight. More preferably, the content is 0.005 to 10.000% by weight, still more preferably 0.010 to 8.000% by weight. In the case of a cream, the chachargan oil content is preferably 0.0001 to 30.000% by weight of the total amount of the cream, more preferably 0.001 to 25.000% by weight, It is even more preferably 0.005 to 22.000% by weight, particularly preferably 0.010 to 20.000% by weight. Here, “lotion” means transparent or translucent, liquid or slightly viscous, for example, lotion, including emulsions and emulsions (these may be called “milk lotions”). do not do.

  Moreover, when using as a skin external preparation for treatment for the purpose of improving rough skin, generally, chachargan oil is highly blended compared with cosmetics. The chachargan oil content of the lotion used for such purpose is preferably 0.005 to 1.000% by weight of the total amount of the lotion, more preferably 0.010 to 1.000% by weight. Preferably, it is 0.050 to 1.000% by weight. Further, the content of the chachargan oil in the emulsion used for such a purpose is preferably 0.05 to 20.00% by weight of the total amount of the emulsion, and 0.50 to 20.00% by weight. Is more preferable, and it is still more preferable that it is 1.00 to 20.00 weight%. Further, the content of the chachargan oil in the cream used for such purpose is preferably 0.05 to 30.00% by weight, and 0.50 to 30.00% by weight of the total amount of the cream. Is more preferable, and it is still more preferable that it is 1.00 to 30.00 weight%.

  The cosmetic or external preparation for skin according to the present invention includes those composed only of chachargan oil (for example, beauty oil), but usually also contains various components required depending on the dosage form and application. To do. Examples of such various components include surfactants, water, ethanol, polyhydric alcohols, higher alcohols, petroleum jelly wax, fats and oils, thickeners, pigments, dyes, fragrances, antibacterial and antifungal agents, UV absorbers, Examples include vitamins, pH adjusters, and the like that are allowed to be used in cosmetics or skin external preparations.

  The cosmetic or external preparation for skin according to the present invention can be produced according to a conventional method, but it is preferable to avoid or keep the chachargan oil exposed to a high temperature (about 80 ° C. or higher) for a short time.

  Hereinafter, the present invention will be described specifically by way of examples.

[Example 1] Production of chachargan oil The fruit of chachargan was pulverized with a mixer, put into a nylon bag, and the bag was squeezed. The liquid squeezed out of the bag was centrifuged to separate it into an oil component (I) and a water-soluble part (fruit juice). In addition, seeds were collected from the straw remaining in the bag. The seed was damaged and squeezed to obtain an oil component (II) in the seed. Oil component (I) and oil component (II) were mixed. All these steps were performed at room temperature.

  As a result of analyzing the constituent fatty acid composition of the triglyceride for the oil component thus obtained, it was as shown in Table 2.

[Example 2] Production of transparent lotion A transparent lotion was produced according to the formulation shown in Table 3.

  Manufacture was performed as follows.

  Dipropylene glycol, chachargan oil, polyethylene glycol (60) hydrogenated castor oil and methylparaben were weighed and dissolved by heating to obtain an oily mixture. Separately, citric acid, sodium citrate, dipotassium glycyrrhizinate, atelocollagen and sodium hyaluronate were dissolved in ion-exchanged water to obtain an aqueous mixed solution. The mixture was heated to about 40 ° C. and the oily mixture was added to the aqueous mixture with stirring. When the whole became transparent, heating was stopped, ion-exchanged water was added as necessary to balance, and stirring was stopped.

  The transparent lotion produced as described above was stored in a constant temperature room at 5 ° C., 25 ° C., and 40 ° C., and turbidity was periodically visually observed. The results are shown in Table 4.

[Example 3] Production of emulsion An emulsion was produced according to the formulation shown in Table 5.

  Manufacture was performed as follows.

  First, butylene glycol, polyethylene glycol (60) hydrogenated castor oil and methylparaben were weighed and dissolved by heating to obtain an oily mixed solution. Separately, weighed carbomer, acrylate polymer, xanthan gum, glycerol, dipotassium glycyrrhizinate, sodium hexametaphosphate and sodium hyaluronate were dissolved in ion-exchanged water to obtain an aqueous mixed solution. The oily mixture was added to the aqueous mixture under warming and stirring. The aqueous phase thus obtained was warmed to 75 ° C. On the other hand, rice germ oil, dimethicone and chachargan oil were weighed and mixed at 75 ° C. to obtain an oil phase. At 75 ° C., the oil phase was added to the aqueous phase and emulsified. When the obtained emulsion was cooled to 40 ° C. or lower, atelocollagen and then potassium hydroxide aqueous solution were added, and ion-exchanged water was further added as necessary to balance, and stirring was stopped.

  The viscosity of the emulsion produced as described above was measured. The viscosity was measured with a rotational viscosity meter BL type manufactured by Tokyo Keiki Co., Ltd. after putting the emulsion in a container with a lid and leaving the container in a thermostatic bath at 25 ° C. for 30 minutes. The viscosity was 4,275 cp.

  Moreover, the said emulsion was preserve | saved at 5 degreeC, 25 degreeC, and a 40 degreeC thermostat, and the external appearance (presence of isolation | separation) was observed regularly. The results are shown in Table 6.

Example 4 Production of Cream A cream was produced according to the formulation shown in Table 7.

  Manufacture was performed as follows.

  First, butylene glycol and methyl paraben were weighed and dissolved by heating to obtain an oily mixture. Separately, honey, glycerol, sodium hyaluronate, dipotassium glycyrrhizinate, carbomer, acrylate polymer and sodium hexametaphosphate were dissolved in ion-exchanged water to obtain an aqueous mixed solution. The oily mixture was added to the aqueous mixture under warming and stirring. The aqueous phase thus obtained was warmed to 75 ° C. On the other hand, rice germ oil, petrolatum, dimethicone, cyclopentasiloxane, chachargan oil and dimethicone polymer were weighed and mixed at 75 ° C. to obtain an oil phase. At 75 ° C., the oil phase was added to the aqueous phase and emulsified. When the obtained emulsion was cooled to 40 ° C. or lower, atelocollagen and then an aqueous potassium hydroxide solution were added, and ion-exchanged water was further added as necessary to balance, and stirring was stopped.

  The viscosity of the emulsion produced as described above was measured. The viscosity was measured using a rotational viscometer BL type manufactured by Tokyo Keiki Co., Ltd. after putting the cream in a container with a lid and leaving the container in a thermostatic bath at 25 ° C. for 30 minutes. The viscosity was 67,000 cp.

  Moreover, the said cream was preserve | saved in a 5 degreeC, 25 degreeC, and 40 degreeC thermostat, and the external appearance (presence of isolation | separation) was observed regularly. The results are shown in Table 8.

[Example 5] Test on effect of improving skin roughness A patient (male) with atopic dermatitis was allowed to use the emulsion produced in Example 3 and the cream produced in Example 4. A thin coat of milk was applied in the morning and a cream was applied on the back in the evening. This was continued for about 4 months.

  FIG. 1 is a photograph of the patient's back before starting the study. FIG. 2 is a photograph of the patient's back about 4 months after the start of the test. Before the test, the cracks (the black spots in FIG. 1) were remarkable, but the skin was clean 4 months after the start of the test. In addition, no side effects such as itching occurred during this test.

It is a photograph which shows the state of the skin before using the emulsion and cream which concern on this invention. It is a photograph which shows the state of the skin after using the emulsion and cream which concern on this invention.

Claims (6)

A cosmetic or external preparation for skin containing chachargan oil. The cosmetic according to claim 1, wherein the cosmetic or skin external preparation is a lotion, emulsion or emulsion, cream, gel, ointment, cosmetic oil, soap, liquid soap, shampoo, hair rinse, hair conditioner, or hair conditioner. Or external preparation for skin. The cosmetic or external preparation for skin according to claim 2, wherein the cosmetic or external preparation for skin is a lotion, and the content of the chachargan oil is 0.0001 to 1.0000% by weight of the total amount of the lotion. The cosmetic or skin external preparation according to claim 2, wherein the cosmetic or the external preparation for skin is an emulsion or an emulsion, and the content of chachargan oil is 0.0001 to 20.000% by weight of the total amount of the emulsion or emulsion. Skin external preparation. The cosmetic or external preparation for skin according to claim 2, wherein the cosmetic or external preparation for skin is a cream, and the content of chachargan oil is 0.0001 to 30.0000% by weight of the total amount of the cream. The cosmetic or external preparation for skin according to any one of claims 1 to 5, comprising only chachargan oil as the oil component.