JP2008307141A - Method and instrument of analyzing brain activity - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a method and an instrument of analyzing brain activity which can precisely catch unbalanced brain activity in either the right or the left. <P>SOLUTION: A measuring means 11 measures a brain magnetic field. An analyzing means 12 acquires intensity distribution data of brain activity on the basis of the brain magnetic field data measured by the measuring means 11 and filters data equally appearing in the right and the left of the brain from the intensity distribution data on the basis of the intensity distribution data of the obtained brain activity. The brain activity analyzer 1 filters data appearing equally in the right and left of the brain from the intensity distribution data. Consequently, the instrument can precisely catch unbalanced brain activity in either the right or the left. <P>COPYRIGHT: (C)2009,JPO&INPIT

Description

  The present invention relates to a brain activity analysis method and a brain activity analysis apparatus that analyze brain activity based on a measurement result of a brain magnetic field.

There is known a method of analyzing the state of brain activity based on the measurement result of the brain magnetic field and displaying the intensity of the brain activity as a region distribution. In this method, for example, the spatial filter method is used as a data analysis technique, whereby the intensity of brain activity can be grasped two-dimensionally or three-dimensionally. Normal,
(1) Measurement of cerebral magnetic field (2) Analysis of cerebral magnetic field measurement data by spatial filter method, etc. (3) Display of brain activity in all or part of the brain (4) Display of brain activity and anatomical information (For example, superposition display with MRI) (5) The brain activity is analyzed and diagnosed by the procedure of brain activity diagnosis by referring to the superposition display.

JP 2006-122086 A

  In a conventional clinical diagnosis, for example, because a pathological phenomenon is a target of analysis, such as a source of wave removal brain activity in an ischemic brain, brain activity is often biased to either the left brain or the right brain. However, actual brain activity includes not only brain activity that is biased to the left or right, but also other background brain activity that usually extends to the left and right of the brain, and the brain activity source to be analyzed is not buried. It becomes clear. In the conventional analysis device, such background brain activity is also displayed at the same time as the brain activity to be analyzed. Therefore, the target brain activity cannot be clearly understood, and the analysis and diagnosis of the brain activity are hindered. there is a possibility.

  An object of the present invention is to provide a brain activity analysis method and a brain activity analysis apparatus that can accurately capture brain activity that is biased to the left or right.

The brain activity analysis method of the present invention is a brain activity analysis method for analyzing brain activity based on a measurement result of a brain magnetic field, the step of measuring the brain magnetic field, and the brain activity based on the measured brain magnetic field data. And the step of removing data appearing evenly on the left and right sides of the brain from the intensity distribution data based on the obtained intensity distribution data of the brain activity. And
According to this brain activity analysis method, since data that appears evenly on the left and right sides of the brain is removed from the intensity distribution data, it is possible to accurately grasp brain activities that are biased to either the left or right.

  A step of displaying the intensity distribution data obtained in the step of removing the data may be provided.

  In the step of displaying the intensity distribution data, the anatomical information of the brain and the distribution data may be displayed in an overlapping manner.

The brain activity analysis apparatus of the present invention is a brain activity analysis apparatus that analyzes brain activity based on a measurement result of a brain magnetic field, a measuring means that measures the brain magnetic field, and a brain based on the measured brain magnetic field data. Analyzing the intensity distribution data of the activity, and based on the obtained intensity distribution data of the brain activity, an analysis means for removing data appearing evenly on the left and right of the brain from the intensity distribution data. Features.
According to this brain activity analyzing apparatus, since data that appears evenly on the left and right sides of the brain is removed from the intensity distribution data, it is possible to accurately grasp brain activities that are biased to either the left or right.

  According to the brain activity analysis method of the present invention, since data that appears evenly on the left and right sides of the brain is removed from the intensity distribution data, it is possible to accurately grasp brain activities that are biased to the left or right.

  According to the brain activity analysis apparatus of the present invention, since data that appears evenly on the left and right sides of the brain is removed from the intensity distribution data, it is possible to accurately grasp brain activities that are biased to the left or right.

  Hereinafter, an embodiment of a brain activity analysis apparatus according to the present invention will be described with reference to FIGS.

  FIG. 1A is a block diagram showing the configuration of the brain activity analysis apparatus of this embodiment.

  As shown in FIG. 1A, the brain activity analysis apparatus 1 according to the present embodiment analyzes a brain activity based on a measurement unit 11 that measures a brain magnetic field, and brain magnetic field data measured by the measurement unit 11. An analysis unit 12 and a display monitor 13 for displaying an analysis result by the analysis unit 12 are provided.

  FIG. 1B is a flowchart showing the operation of the brain activity analysis apparatus 1.

  In step S1 of FIG. 1B, the magnetic field is measured by the measuring means 11. Next, in step S2, the analysis means 12 obtains intensity distribution data of brain activity based on the brain magnetic field data measured by the measurement means 11 using a spatial filter method or the like. Next, in step S3, the analysis result by the analyzing means 12 is displayed on the display monitor 13.

  FIG. 2A is a diagram illustrating a display image on the display monitor 13. As shown in FIG. 2 (a), the intensity distribution of the brain activity is obtained by the analyzing means 12, and the intensity of the brain activity is displayed on the display monitor 13 as a shade of display color for each brain region. In the example of FIG. 2A, the intensity distribution of brain activity is displayed for one section of the brain. The center line 21 indicates a plane that equally divides the brain into left and right.

  Next, in step S <b> 4, the analysis means 12 removes the intensity of the background brain activity that appears evenly from the right and left from the displayed intensity distribution of the brain activity and reflects it on the display image of the display monitor 13.

  FIG. 3A shows the intensity of brain activity on the straight line 22 in the display image of FIG. In FIG. 3A, the straight line 22 in the X direction is perpendicular to the plane indicated by the center line 21 and the origin (X = 0) is on the center line 21. In step S4, the difference in intensity at the target position with respect to the center line 21 is extracted. Specifically, the intensity A (X) of the coordinate X on the straight line 22 is compared with the intensity A (−X) of the coordinate −X, and the smaller intensity is defined as Xmin. Then, as shown in FIG. 3B, the new intensity B (X) of the coordinate X on the straight line 22 is defined as “intensity A (X) −Xmin”, and the new intensity B (−X) of the coordinate −X. Is “strength A (−X) −Xmin”. By executing such processing for the entire analysis region, a signal of background brain activity that appears evenly on the left and right is removed, and an intensity difference between the left and right brain activities is extracted.

  FIG. 2B shows a display image on the display monitor 13 after the background brain activity signal is removed. Thus, by removing the signal of the background brain activity, the left and right deviations of the brain activity are clearly displayed.

  Next, in step S5, on the display monitor 13, the display image after the background brain activity signal corresponding to FIG. 2B is removed and the anatomical information (for example, MRI) are superimposed and displayed. To finish the process. By referring to such superimposed display, analysis and diagnosis of brain activity can be performed.

  As described above, according to the brain activity analysis apparatus of the present embodiment, by removing the background brain activity signal, the brain activity biased to either the left or right, such as the wave-removing brain activity source in the ischemic brain, is clarified. Since it can be captured, the accuracy of diagnosis can be improved.

  Further, comparison with analysis images by other clinical image apparatuses such as SPECT, PET, and MEG becomes easy. For example, SPECT or PET can be compared with the measurement result of cerebral blood flow, and MEG can be compared with the measurement result of brain activity. Therefore, diagnosis can be performed from various viewpoints, and the accuracy of diagnosis can be improved in this respect.

  As described above, according to the brain activity analysis method and the brain activity analysis apparatus of the present invention, since the data appearing evenly on the left and right sides of the brain is removed from the intensity distribution data, the brain activity biased to either the left or right Can be accurately captured.

  The scope of application of the present invention is not limited to the above embodiment. The present invention can be widely applied to a brain activity analysis method and a brain activity analysis apparatus that analyze brain activity based on a measurement result of a brain magnetic field.

It is a figure which shows the brain activity analyzer of one Embodiment, (a) is a block diagram which shows the structure of the brain activity analyzer of this embodiment, (b) is a flowchart which shows operation | movement of a brain activity analyzer. It is a figure which illustrates the display image of a display monitor, (a) is a figure which illustrates the display image before removing the signal of background brain activity, (b) is the display after removing the signal of background brain activity. The figure which illustrates an image. It is a figure which shows the intensity | strength of the brain activity displayed on a display image, (a) is a figure which illustrates the intensity | strength before removing the signal of background brain activity, (b) removed the signal of background brain activity The figure which illustrates the intensity | strength after.

Explanation of symbols

DESCRIPTION OF SYMBOLS 1 Brain activity analyzer 11 Measuring means 12 Analyzing means

Claims (4)

In the brain activity analysis method that analyzes brain activity based on the measurement result of the brain magnetic field,
Measuring the brain magnetic field;
Obtaining intensity distribution data of brain activity based on the measured brain magnetic field data, and based on the obtained intensity distribution data of brain activity, the intensity distribution data appear evenly on the left and right of the brain. Removing existing data;
A brain activity analysis method comprising: A brain activity analysis method comprising the step of displaying intensity distribution data obtained in the step of removing the data. 3. The brain activity analysis method according to claim 2, wherein in the step of displaying the intensity distribution data, the anatomical information of the brain and the distribution data are displayed in a superimposed manner. In the brain activity analysis device that analyzes brain activity based on the measurement result of brain magnetic field,
A measuring means for measuring the brain magnetic field;
Based on the measured brain magnetic field data, brain activity intensity distribution data is obtained, and on the basis of the obtained brain activity intensity distribution data, data appearing evenly on the left and right sides of the brain are obtained. Analysis means to be removed;
A brain activity analysis apparatus comprising:

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