JP2006076984A - Hair-growing/restoring agent - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a highly safe hair-growing/restoring agent showing a high hair-growing/restoring effect. <P>SOLUTION: The hair-restoring agent comprises at least one compound chosen from the group consisting of procainamide hydrochloride, disodium hydrogenphosphate, potassium pyrosulfite, benzenecarboxylic acid, L(+)-ascorbic acid, lanolin, vaseline, paraffin oil, glycerol, whale wax, beeswax, sodium borate, cucumber extract, adenine, guanine, uracil, cytosine, thymine, estrone, estradiol and estriol as an active ingredient. <P>COPYRIGHT: (C)2006,JPO&NCIPI

Description

  The present invention relates to a hair growth and hair growth agent that has remarkable hair growth and hair growth effects and does not cause significant side effects on the living body.

Various researches and developments have been made on hair growth and hair growth agents, and hormone agents, blood flow promoters, male hormone receptor inhibitors, steroid-5α-reductase 7 inhibitors, vitamins, immunosuppressants, etc. Although known, their usefulness is not fully satisfactory.
PATENT SPECIFICATION (11) 1 256 235

  However, in the conventional plant extract ingredients, there is a drawback that the hair growth effect is not sufficient even though it is safe, and no active ingredients with excellent hair growth and hair growth effects and excellent safety have yet been found. It is.

  As a result of various investigations to find a hair-growth component having excellent effectiveness, the present inventor has found that certain compounds have an excellent hair-growth effect and completed the present invention.

  As hair restorer, procainamide hydrochloride, disodium hydrogen phosphate, potassium pyrosulfite, benzenecarboxylic acid, L (+)-ascorbic acid, lanolin, petrolatum, paraffin oil, glycerol, spermaceti, beeswax, sodium borate, A hair restorer containing as an active ingredient one or more compounds selected from the group consisting of cucumber extract, adenine, guanine, uracil, cytosine, thymine, estrone, estradiol, and estriol.

  The compounds that are the active ingredients of the present invention are known, and are commercially available in pharmaceuticals and health supplements. For example, it is marketed under the names such as Tagero beer cane caliber, Tagerobitacan injection, Gerovital etch three, RNA / DNA oral agent, and estrogen oral agent (all are trade names).

  In order to obtain a higher effect from the hair growth and hair restorer used in the present invention, 25 to 30 grams of active ingredient is added to 50 cc of purified water (Taiyo Pharmaceutical Co., Ltd.), heated at 80 to 100 ° C. for 5 minutes, and allowed to stand. A 60 cc lotion agent is preferred by removing precipitates with filter paper and extracting 40 cc of liquid and then adding 20 cc of ethanol 99.5% (Wako Pure Chemical Industries, Ltd.). If the active ingredient is less than 25 grams, a sufficient effect cannot be obtained. On the other hand, if the active ingredient exceeds 30 grams, an unpleasant irritation is given to the scalp.

  It is preferable to apply 1 cc of the hair growth lotion used in the present invention once a day in the morning and evening.

  The hair restorer of the present invention can be produced by a conventional method as an external preparation such as a lotion preparation, emulsion, cream, ointment, gel, aerosol, etc.

  Hereinafter, the present invention will be described in more detail with reference to examples.

  The hair growth and hair growth lotion used in the present invention was applied to 5 thin and bald men for 6 months as follows. After washing the hair, the scalp is naturally dried for about 1 hour, or dried with a dryer and dried thoroughly, and 1 cc of the above lotion preparation is applied evenly to the part that has been boiled once a day in the morning and evening, and massaged to penetrate well. Table 1 shows the effects of the hair growth and hair restorer used in the present invention.

  The hair growth effect of Table 1 will be described in detail. The hair growth and hair growth agent of the present invention differed from person to person, but remarkable hair growth was observed for Mr. W and Mr. T. Mr. S, who was 59 years old, reached nearly 30% of the bald area at the top of the head. In addition, the M-shaped baldness in the frontal region was slower than the top of the head, but hair growth was observed. The number of Mr. K and Mr. K reached 77. In addition, Mr. S, Mr. K, and Mr. K returned to their original hair color (although it turned black) to some extent along with the hair growth. There were no side effects.

Comparison of raw material content

  A lotion preparation with an active ingredient content of less than 25 grams cannot provide a sufficient effect, and a lotion preparation with an active ingredient content of 30 grams or more is unfavorable because it irritate the skin and feel uncomfortable. Accordingly, the inventors have found out that a lotion preparation having an active ingredient content of 25 to 30 grams is excellent in hair growth and hair growth, and completed.

Claims (2)

  Procainamide hydrochloride, disodium hydrogen phosphate, potassium pyrosulfite, benzenecarboxylic acid, L (+)-ascorbic acid, lanolin, petrolatum, paraffin oil, glycerol, spermaceti, beeswax, sodium borate, cucumber extract, A hair restorer comprising as an active ingredient one or more compounds selected from the group consisting of adenine, guanine, uracil, cytosine, thymine, estrone, estradiol, and estriol.   The hair restorer according to claim 1, which is an external preparation.