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JP2005126418A - Substituted benzanilide and pest control agent - Google Patents

Substituted benzanilide and pest control agent Download PDF

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JP2005126418A
JP2005126418A JP2004280961A JP2004280961A JP2005126418A JP 2005126418 A JP2005126418 A JP 2005126418A JP 2004280961 A JP2004280961 A JP 2004280961A JP 2004280961 A JP2004280961 A JP 2004280961A JP 2005126418 A JP2005126418 A JP 2005126418A
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Eitatsu Ikeda
栄達 池田
Kaneshige Maeda
兼成 前田
Hirotaka Furukawa
裕貴 古川
Shinji Takii
新自 瀧井
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Nissan Chemical Corp
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Nissan Chemical Corp
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Abstract

<P>PROBLEM TO BE SOLVED: To provide a new agrochemical, particularly insecticidal and acaricidal agent. <P>SOLUTION: The pest control agent includes a substituted benzanilide represented by general formula (1) [wherein W<SP>1</SP>and W<SP>2</SP>are each O or S atom; X is a halogen atom or the like; Y is a 1-6C alkyl or the like; R<SP>1</SP>is a 1-6C alkylthio(a 1-6C)alkyl; R<SP>2</SP>and R<SP>3</SP>are each H or the like; R<SP>4</SP>is a 1-6C haloalkyl; R<SP>5</SP>is a phenoxy(1-6C)haloalkyl, or L or the like; R<SP>6</SP>is H atom or a 1-6C alkylcarbonyl; L represents an aromatic heterocyclic ring, for example, L-1 through L-4, L-8 through L-13, L-15 through L-23, L-45 through L-52 or L-53 and the like; Z is a halogen atom or a 1-6C haloalkoxy(1-6C)haloalkoxy; m and n are each independently an integer of 0 through 4 and p1 is an integer of 1 through 5]. <P>COPYRIGHT: (C)2005,JPO&NCIPI

Description

本発明は、新規な置換ベンズアニリド化合物及びその塩、並びに該化合物を有効成分として含有することを特徴とする有害生物防除剤に関するものである。本発明における有害生物防除剤とは、農園芸分野又は畜産、衛生分野（動物薬や家庭用、業務用殺虫剤）における有害な節足動物を対象とした害虫防除剤を意味する。また、本発明における農薬とは、農園芸分野における殺虫・殺ダニ剤、殺線虫剤、除草剤及び殺菌剤を意味する。   The present invention relates to a novel substituted benzanilide compound and a salt thereof, and a pest control agent comprising the compound as an active ingredient. The pest control agent in the present invention means a pest control agent for harmful arthropods in the fields of agriculture, horticulture, animal husbandry, and hygiene (animal medicine, household use, commercial insecticide). The agrochemical in the present invention means an insecticide / acaricide, nematicide, herbicide and fungicide in the field of agriculture and horticulture.

従来、特定の置換ベンズアニリド誘導体が、サイトカイン産生阻害活性、バソプレッシン拮抗活性等を有し、医薬品として用いられることが知られている（例えば、特許文献１〜３参照。）。また、特定の置換ベンズアニリド誘導体が、殺虫活性を有することが知られている（例えば、特許文献４〜１２参照。）。しかしながら、本発明に係る置換ベンズアニリド化合物に関しては何ら開示されていない。
国際公開第９８／０２４７７１号パンフレット 国際公開第９９／０５１５８０号パンフレット 特開２００２−２４９４７３号公報 欧州特許出願公開第０９１９５４２号明細書 欧州特許出願公開第１００６１０７号明細書 国際公開第０１／０２１５７６号パンフレット 国際公開第０１／０４６１２４号パンフレット 特開２００１−３３５５５９号公報 国際公開第０２／０６２８０７号パンフレット 国際公開第０２／０９４７６５号パンフレット 国際公開第２００４／０００７９６号パンフレット 国際公開第２００４／０１８４１５号パンフレット Conventionally, it is known that a specific substituted benzanilide derivative has a cytokine production inhibitory activity, a vasopressin antagonistic activity, and the like, and is used as a pharmaceutical product (see, for example, Patent Documents 1 to 3). Moreover, it is known that a specific substituted benzanilide derivative has insecticidal activity (for example, refer patent documents 4-12). However, there is no disclosure regarding the substituted benzanilide compound according to the present invention.
International Publication No. 98/024771 Pamphlet WO99 / 051580 pamphlet JP 2002-249473 A European Patent Application No. 0919542 European Patent Application No. 1006107 International Publication No. 01/021576 pamphlet International Publication No. 01/046124 Pamphlet JP 2001-335559 A International Publication No. 02/062807 Pamphlet International Publication No. 02/094765 Pamphlet International Publication No. 2004/000796 Pamphlet International Publication No. 2004/018415 Pamphlet

有害生物防除剤、例えば殺虫剤や殺菌剤の長年にわたる使用により、近年、病害虫が抵抗性を獲得し、従来用いられてきた殺虫剤や殺菌剤による防除が困難になっている。また、既存の有害生物防除剤の一部のものは毒性が高く、或いはあるものは長期の残留性により、生態系を乱しつつある。このような状況下、低毒性かつ低残留性の新規な有害生物防除剤の開発が常に期待されている。   Pest control agents such as insecticides and fungicides have been used for many years, and in recent years, pests have acquired resistance, making it difficult to control them with conventionally used insecticides and fungicides. Also, some of the existing pest control agents are highly toxic or some are disrupting the ecosystem due to long-term persistence. Under such circumstances, development of a novel pesticide with low toxicity and low persistence is always expected.

本発明者らは、上記の課題解決を目標に鋭意研究を重ねた結果、本発明に係る下記一般式（１）で表される新規な置換ベンズアニリド化合物が優れた有害生物防除活性、特に殺虫・殺ダニ活性を示し、且つ、ホ乳動物、魚類及び益虫等の非標的生物に対してほとんど悪影響の無い、極めて有用な化合物であることを見い出し、本発明を完成した。   As a result of intensive research aimed at solving the above problems, the present inventors have found that the novel substituted benzanilide compound represented by the following general formula (1) according to the present invention has excellent pest control activity, particularly insecticide The present invention was completed by discovering that it is a very useful compound that exhibits acaricidal activity and has almost no adverse effect on non-target organisms such as mammals, fish and beneficial insects.

すなわち、本発明は下記〔１〕〜〔８〕に関するものである。   That is, the present invention relates to the following [1] to [8].

〔１〕 一般式（１）：   [1] General formula (1):

Figure 2005126418
Figure 2005126418

［式中、W1及びW2は、各々独立して酸素原子又は硫黄原子を表し、
Xは、ハロゲン原子、シアノ、ニトロ、アジド、-SCN、-SF5、C1〜C6アルキル、R7によって任意に置換された(C1〜C6)アルキル、C3〜C8シクロアルキル、R7によって任意に置換された(C3〜C8)シクロアルキル、C2〜C6アルケニル、R7によって任意に置換された(C2〜C6)アルケニル、C3〜C8シクロアルケニル、C3〜C8ハロシクロアルケニル、C2〜C6アルキニル、R7によって任意に置換された(C2〜C6)アルキニル、-OH、-OR8、-OS(O)2R8、-SH、-S(O)rR8、-CHO、-C(O)R9、-C(O)OR9、-C(O)SR9、-C(O)NHR10、-C(O)N(R10)R9、-C(S)OR9、-C(S)SR9、-C(S)NHR10、-C(S)N(R10)R9、-CH=NOR11、-C(R9)=NOR11、-S(O)2OR9、-S(O)2NHR10、-S(O)2N(R10)R9、-Si(R13)(R14)R12、フェニル、(Z)p1によって置換されたフェニル、L又はMを表し、mが２、３又は４を表すとき、各々のXは互いに同一であっても又は互いに相異なっていてもよく、
さらに、２つのXが隣接する場合には、隣接する２つのXは-CH2CH2CH2-, -CH2CH2O-, -CH2OCH2-, -OCH2O-, -CH2CH2S-, -CH2SCH2-, -CH2CH2N(R15)-, -CH2N(R15)CH2-, -CH2CH2CH2CH2-, -CH2CH2CH2O-, -CH2CH2OCH2-, -CH2OCH2O-, -OCH2CH2O-, -OCH2CH2S-, -CH2CH=CH-, -OCH=CH-, -SCH=CH-, -N(R15)CH=CH-, -OCH=N-, -SCH=N-, -N(R15)CH=N-, -N(R15)N=CH-, -CH=CHCH=CH-, -OCH2CH=CH-, -N=CHCH=CH-, -N=CHCH=N-又は-N=CHN=CH-を形成することにより、２つのXのそれぞれが結合する炭素原子と共に５員環又は６員環を形成してもよく、このとき、環を形成する各々の炭素原子に結合した水素原子はZによって任意に置換されていてもよく、さらに、同時に２個以上のZで置換されている場合、各々のZは互いに同一であっても又は互いに相異なっていてもよく、
Yは、ハロゲン原子、シアノ、ニトロ、C1〜C6アルキル、R7によって任意に置換された(C1〜C6)アルキル、C3〜C8シクロアルキル、-OR8、-S(O)rR8、-NH2、C1〜C6アルキルアミノ、ジ(C1〜C6アルキル)アミノ又は-Si(R13)(R14)R12を表し、nが２、３又は４を表すとき、各々のYは互いに同一であっても又は互いに相異なっていてもよく、
さらに、２つのYが隣接する場合には、隣接する２つのYは-CH2CH2CH2-, -CH2CH2O-, -CH2OCH2-, -OCH2O-, -CH2CH2S-, -CH2SCH2-, -SCH2S-, -CH2CH2CH2CH2-, -CH2CH2CH2O-, -CH2CH2OCH2-, -CH2OCH2O-, -OCH2CH2O-, -OCH2CH2S-, -SCH2CH2S-, -OCH=N-又は-SCH=N-を形成することにより、２つのYのそれぞれが結合する炭素原子と共に５員環又は６員環を形成してもよく、このとき、環を形成する各々の炭素原子に結合した水素原子はZによって任意に置換されていてもよく、さらに、同時に２個以上のZで置換されている場合、各々のZは互いに同一であっても又は互いに相異なっていてもよく、
R1は、水素原子、シアノ、C1〜C12アルキル、R16によって任意に置換された(C1〜C12)アルキル、C3〜C12シクロアルキル、R16によって任意に置換された(C3〜C12)シクロアルキル、C3〜C12アルケニル、R16によって任意に置換された(C3〜C12)アルケニル、C3〜C12シクロアルケニル、C3〜C12ハロシクロアルケニル、C3〜C12アルキニル、R16によって任意に置換された(C3〜C12)アルキニル、-OH、C1〜C8アルコキシ、C3〜C8アルケニルオキシ、C3〜C8ハロアルケニルオキシ、フェノキシ、(Z)p1によって置換されたフェノキシ、フェニル(C1〜C4)アルコキシ、(Z)p1によって置換されたフェニル(C1〜C4)アルコキシ、-N(R20)R19、フェニル、(Z)p1によって置換されたフェニル、L又はMを表し、
R2及びR3は、各々独立して水素原子、シアノ、C1〜C12アルキル、R16によって任意に置換された(C1〜C12)アルキル、C3〜C12アルケニル、C3〜C12ハロアルケニル、C3〜C12アルキニル、C3〜C12ハロアルキニル、-OH、C1〜C8アルコキシ、C1〜C6アルキルチオ、C1〜C6ハロアルキルチオ、フェニルチオ、(Z)p1によって置換されたフェニルチオ、-S(O)2R9、-SN(R18)R17、-S(O)2N(R10)R9、-N(R20)R19、-C(O)R9、-C(O)OR9、-C(O)SR9、-C(O)N(R10)R9、-C(S)OR9、-C(S)SR9、-C(S)N(R10)R9、フェニル又は(Z)p1によって置換されたフェニルを表すか、或いは、R2はR1と一緒になってC2〜C6アルキレン鎖を形成することにより、結合する窒素原子と共に３〜７員環を形成してもよいことを表し、このときこのアルキレン鎖は酸素原子、硫黄原子又は窒素原子を１個含んでもよく、且つハロゲン原子、C1〜C6アルキル基、C1〜C6ハロアルキル基、C1〜C6アルコキシ基、C1〜C6アルキルカルボニル基又はC1〜C6アルコキシカルボニル基によって任意に置換されていてもよく、
R4は、C1〜C6アルキル、C1〜C6ハロアルキル、R21によって任意に置換された(C1〜C6)アルキル、R21によって任意に置換された(C1〜C6)ハロアルキル、C3〜C8シクロアルキル、C3〜C8ハロシクロアルキル、R21によって任意に置換された(C3〜C8)シクロアルキル、R21によって任意に置換された(C3〜C8)ハロシクロアルキル、C3〜C6アルケニル、C3〜C6ハロアルケニル、C3〜C6アルキニル、C3〜C6ハロアルキニル、フェニル、(Z)p1によって置換されたフェニル、L又はMを表し、
R5は、シアノ、R21によって任意に置換された(C1〜C6)アルキル、R21によって任意に置換された(C1〜C6)ハロアルキル、R21によって任意に置換された(C3〜C8)シクロアルキル、R21によって任意に置換された(C3〜C8)ハロシクロアルキル、R21によって任意に置換された(C2〜C6)アルケニル、C3〜C8シクロアルケニル、C3〜C8ハロシクロアルケニル、R21によって任意に置換された(C2〜C6)アルキニル、-OR8、-S(O)rR8、-N(R10)R9、-CHO、-C(O)R9、-CH=NOR11、-C(R9)=NOR11、-C(O)OR9、-C(O)SR9、-C(O)NHR10、-C(O)N(R10)R9、-C(S)OR9、-C(S)SR9、-C(S)NHR10、-C(S)N(R10)R9、フェニル、(Z)p1によって置換されたフェニル、ビフェニル、(Z)p1によって置換されたビフェニル、フェノキシフェニル、(Z)p1によって置換されたフェノキシフェニル、ピリジルオキシフェニル、(Z)p1によって置換されたピリジルオキシフェニル、フェニルチオフェニル、(Z)p1によって置換されたフェニルチオフェニル、フェニルスルフィニルフェニル、(Z)p1によって置換されたフェニルスルフィニルフェニル、フェニルスルホニルフェニル、(Z)p1によって置換されたフェニルスルホニルフェニル、L又はMを表すか、或いは、隣接位に存在するYと一緒になってC2〜C3アルキレン鎖を形成することにより、ベンゼン環と縮合する５〜６員環を形成してもよいことを表し、このときこのアルキレン鎖は酸素原子、硫黄原子又は窒素原子を１個含んでもよく、且つハロゲン原子又はC1〜C6ハロアルキル基によって任意に置換されていてもよく、
R6は、水素原子、C1〜C6アルキル、C1〜C6ハロアルキル、R21によって任意に置換された(C1〜C6)アルキル、R21によって任意に置換された(C1〜C6)ハロアルキル、C3〜C8シクロアルキル、C3〜C6アルケニル、C3〜C6ハロアルケニル、フェニル(C3〜C6)アルケニル、(Z)p1によって置換されたフェニル(C3〜C6)アルケニル、C3〜C8シクロアルケニル、C3〜C6アルキニル、C3〜C6ハロアルキニル、フェニル(C3〜C6)アルキニル、(Z)p1によって置換されたフェニル(C3〜C6)アルキニル、-S(O)2R9、-C(O)R9、-C(O)OR9、-C(O)SR9、-C(S)OR9、-C(S)SR9、-C(O)NHR10、-C(O)N(R10)R9、-C(S)NHR10、-C(S)N(R10)R9、-Si(R13)(R14)R12、-P(O)(OR22)2、-P(S)(OR22)2又はMを表し、
Lは、式L-1から式L-58までの何れかで表される芳香族複素環を表し、 [Wherein, W 1 and W 2 each independently represent an oxygen atom or a sulfur atom,
X is a halogen atom, cyano, nitro, azido, -SCN, -SF 5, C 1 ~C 6 alkyl, optionally substituted by R 7 (C 1 ~C 6) alkyl, C 3 -C 8 cycloalkyl , optionally substituted by R 7 (C 3 ~C 8) cycloalkyl, C 2 -C 6 alkenyl, optionally substituted by R 7 (C 2 ~C 6) alkenyl, C 3 -C 8 cycloalkenyl , C 3 -C 8 halocycloalkyl cycloalkenyl, C 2 -C 6 alkynyl, optionally substituted by R 7 (C 2 ~C 6) alkynyl, -OH, -OR 8, -OS ( O) 2 R 8, -SH, -S (O) r R 8 , -CHO, -C (O) R 9 , -C (O) OR 9 , -C (O) SR 9 , -C (O) NHR 10 , -C ( O) N (R 10 ) R 9 , -C (S) OR 9 , -C (S) SR 9 , -C (S) NHR 10 , -C (S) N (R 10 ) R 9 , -CH = NOR 11 , -C (R 9 ) = NOR 11 , -S (O) 2 OR 9 , -S (O) 2 NHR 10 , -S (O) 2 N (R 10 ) R 9 , -Si (R 13 ) (R 14) R 12, phenyl, (Z) phenyl substituted by p1, represents L or M, when m represents 2, 3 or 4, each X May be the or different from each other the same as each other,
Further, when two Xs are adjacent to each other, the two adjacent Xs are -CH 2 CH 2 CH 2- , -CH 2 CH 2 O-, -CH 2 OCH 2- , -OCH 2 O-, -CH 2 CH 2 S-, -CH 2 SCH 2- , -CH 2 CH 2 N (R 15 )-, -CH 2 N (R 15 ) CH 2- , -CH 2 CH 2 CH 2 CH 2- , -CH 2 CH 2 CH 2 O-, -CH 2 CH 2 OCH 2- , -CH 2 OCH 2 O-, -OCH 2 CH 2 O-, -OCH 2 CH 2 S-, -CH 2 CH = CH-,- OCH = CH-, -SCH = CH-, -N (R 15 ) CH = CH-, -OCH = N-, -SCH = N-, -N (R 15 ) CH = N-, -N (R 15 By forming N = CH-, -CH = CHCH = CH-, -OCH 2 CH = CH-, -N = CHCH = CH-, -N = CHCH = N- or -N = CHN = CH- A 5-membered ring or a 6-membered ring may be formed together with the carbon atom to which each of two Xs is bonded. At this time, the hydrogen atom bonded to each carbon atom forming the ring is optionally substituted by Z. In addition, when simultaneously substituted with two or more Z, each Z may be the same as or different from each other,
Y is a halogen atom, cyano, nitro, C 1 -C 6 alkyl, optionally substituted by R 7 (C 1 ~C 6) alkyl, C 3 -C 8 cycloalkyl, -OR 8, -S (O ) r R 8 , —NH 2 , C 1 -C 6 alkylamino, di (C 1 -C 6 alkyl) amino or —Si (R 13 ) (R 14 ) R 12 , n is 2, 3 or 4 Each Y may be the same as or different from each other;
Further, when two Ys are adjacent to each other, the two adjacent Ys are —CH 2 CH 2 CH 2 —, —CH 2 CH 2 O—, —CH 2 OCH 2 —, —OCH 2 O—, —CH 2 CH 2 S-, -CH 2 SCH 2- , -SCH 2 S-, -CH 2 CH 2 CH 2 CH 2- , -CH 2 CH 2 CH 2 O-, -CH 2 CH 2 OCH 2 -,- By forming CH 2 OCH 2 O-, -OCH 2 CH 2 O-, -OCH 2 CH 2 S-, -SCH 2 CH 2 S-, -OCH = N- or -SCH = N- A 5-membered ring or a 6-membered ring may be formed together with the carbon atom to which each Y is bonded, and at this time, the hydrogen atom bonded to each carbon atom forming the ring may be optionally substituted by Z Furthermore, when two or more Z are substituted at the same time, each Z may be the same as or different from each other,
R 1 is hydrogen atom, cyano, optionally substituted by C 1 -C 12 alkyl, optionally substituted by R 16 (C 1 ~C 12) alkyl, C 3 -C 12 cycloalkyl, R 16 ( C 3 -C 12) cycloalkyl, C 3 -C 12 alkenyl, optionally substituted by R 16 (C 3 ~C 12) alkenyl, C 3 -C 12 cycloalkenyl, C 3 -C 12 halo cycloalkenyl, C 3 -C 12 alkynyl, optionally substituted by R 16 (C 3 ~C 12) alkynyl, -OH, C 1 -C 8 alkoxy, C 3 -C 8 alkenyloxy, C 3 -C 8 haloalkenyloxy , phenoxy, (Z) p1 phenoxy substituted by phenyl (C 1 ~C 4) alkoxy, (Z) phenyl substituted by p1 (C 1 ~C 4) alkoxy, -N (R 20) R 19 , Phenyl, (Z) represents phenyl, L or M substituted by p1 ,
R 2 and R 3 are each independently a hydrogen atom, cyano, C 1 -C 12 alkyl, (C 1 -C 12 ) alkyl optionally substituted with R 16 , C 3 -C 12 alkenyl, C 3- C 12 haloalkenyl, C 3 -C 12 alkynyl, C 3 -C 12 haloalkynyl, -OH, C 1 -C 8 alkoxy, C 1 -C 6 alkylthio, C 1 -C 6 haloalkylthio, phenylthio, (Z) phenylthio substituted by p1, -S (O) 2 R 9, -SN (R 18) R 17, -S (O) 2 N (R 10) R 9, -N (R 20) R 19, -C (O) R 9 , -C (O) OR 9 , -C (O) SR 9 , -C (O) N (R 10 ) R 9 , -C (S) OR 9 , -C (S) SR 9 , -C (S) N (R 10) R 9, or represents phenyl which is substituted by phenyl or (Z) p1, or, R 2 is formed a C 2 -C 6 alkylene chain together with R 1 This represents that a 3- to 7-membered ring may be formed together with the nitrogen atom to be bonded. At this time, the alkylene chain has an oxygen atom, a sulfur atom or a nitrogen atom. Pieces comprise may, and halogen atom, C 1 -C 6 alkyl group, C 1 -C 6 haloalkyl group, C 1 -C 6 alkoxy group, C 1 -C 6 alkylcarbonyl group or a C 1 -C 6 alkoxycarbonyl group Optionally substituted by
R 4 is optionally substituted by C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, optionally substituted by R 21 (C 1 ~C 6) alkyl, R 21 (C 1 ~C 6) haloalkyl, C 3 -C 8 cycloalkyl, C 3 -C 8 halocycloalkyl, optionally substituted by R 21 (C 3 ~C 8) cycloalkyl, optionally substituted by R 21 (C 3 ~C 8) halocycloalkyl, C 3 -C 6 alkenyl, C 3 -C 6 haloalkenyl, C 3 -C 6 alkynyl, C 3 -C 6 haloalkynyl, phenyl, phenyl substituted by (Z) p1, L or Represents M,
R 5 is cyano, optionally substituted by R 21 (C 1 ~C 6) alkyl, optionally substituted by optionally substituted by R 21 (C 1 ~C 6) haloalkyl, R 21 (C 3 -C 8) cycloalkyl, optionally substituted optionally substituted by R 21 (C 3 ~C 8) halocycloalkyl, the R 21 (C 2 ~C 6) alkenyl, C 3 -C 8 cycloalkyl alkenyl, C 3 -C 8 halocycloalkyl cycloalkenyl, optionally substituted by R 21 (C 2 ~C 6) alkynyl, -OR 8, -S (O) r R 8, -N (R 10) R 9, -CHO, -C (O) R 9 , -CH = NOR 11 , -C (R 9 ) = NOR 11 , -C (O) OR 9 , -C (O) SR 9 , -C (O) NHR 10 , -C (O) N (R 10 ) R 9 , -C (S) OR 9 , -C (S) SR 9 , -C (S) NHR 10 , -C (S) N (R 10 ) R 9 , phenyl, (Z) phenyl substituted by p1, biphenyl, biphenyl substituted by (Z) p1, phenoxyphenyl, phenoxyphenyl substituted by (Z) p1, Pirijiruo Shifeniru, (Z) pyridyloxy phenyl substituted by p1, phenylthiophenyl, (Z) phenylthio phenyl substituted by p1, phenylsulfinyl phenyl, phenylsulfinyl phenyl substituted by (Z) p1, phenylsulfonyl phenyl, (Z) phenylsulfonyl phenyl substituted by p1, or represents L or M, or by forming a C 2 -C 3 alkylene chain together with Y being present on the adjacent position, it is condensed with a benzene ring Represents that a 5- to 6-membered ring may be formed, in which case the alkylene chain may contain one oxygen atom, sulfur atom or nitrogen atom, and optionally by a halogen atom or a C 1 -C 6 haloalkyl group May be replaced,
R 6 is a hydrogen atom, C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, optionally substituted by R 21 (C 1 ~C 6) alkyl, optionally substituted by R 21 (C 1 ~ C 6 ) haloalkyl, C 3 -C 8 cycloalkyl, C 3 -C 6 alkenyl, C 3 -C 6 haloalkenyl, phenyl (C 3 -C 6 ) alkenyl, (Z) phenyl substituted by p1 (C 3 -C 6) alkenyl, C 3 -C 8 cycloalkenyl, C 3 -C 6 alkynyl, C 3 -C 6 haloalkynyl, phenyl (C 3 ~C 6) alkynyl, phenyl substituted by (Z) p1 (C 3 -C 6) alkynyl, -S (O) 2 R 9 , -C (O) R 9, -C (O) OR 9, -C (O) SR 9, -C (S) OR 9, -C (S) SR 9 , -C (O) NHR 10 , -C (O) N (R 10 ) R 9 , -C (S) NHR 10 , -C (S) N (R 10 ) R 9 , -Si (R 13 ) (R 14 ) R 12 , -P (O) (OR 22 ) 2 , -P (S) (OR 22 ) 2 or M,
L represents an aromatic heterocycle represented by any one of formulas L-1 to L-58,

Figure 2005126418
Figure 2005126418

Figure 2005126418
Figure 2005126418

Mは、式M-1から式M-28までの何れかで表される飽和複素環を表し、   M represents a saturated heterocyclic ring represented by any one of formulas M-1 to M-28;

Figure 2005126418
Figure 2005126418

Zは、ハロゲン原子、シアノ、ニトロ、アジド、-SCN、-SF5、C1〜C6アルキル、C1〜C6ハロアルキル、C1〜C3アルコキシ(C1〜C3)アルキル、C1〜C3ハロアルコキシ(C1〜C3)アルキル、シアノ(C1〜C6)アルキル、ヒドロキシ(C1〜C3)ハロアルキル、C1〜C3アルコキシ(C1〜C3)ハロアルキル、C1〜C3ハロアルコキシ(C1〜C3)ハロアルキル、C1〜C3アルキルチオ(C1〜C3)アルキル、C1〜C3ハロアルキルチオ(C1〜C3)アルキル、C1〜C3アルキルスルフィニル(C1〜C3)アルキル、C1〜C3ハロアルキルスルフィニル(C1〜C3)アルキル、C1〜C3アルキルスルホニル(C1〜C3)アルキル、C1〜C3ハロアルキルスルホニル(C1〜C3)アルキル、C3〜C8シクロアルキル、C3〜C8ハロシクロアルキル、C2〜C6アルケニル、C2〜C6ハロアルケニル、C3〜C8シクロアルケニル、C3〜C8ハロシクロアルケニル、C2〜C6アルキニル、C2〜C6ハロアルキニル、-OH、C1〜C6アルコキシ、C1〜C6ハロアルコキシ、C1〜C3ハロアルコキシ(C1〜C3)ハロアルコキシ、C2〜C6アルケニルオキシ、C2〜C6ハロアルケニルオキシ、C3〜C6アルキニルオキシ、C3〜C6ハロアルキニルオキシ、C1〜C6アルキルスルホニルオキシ、C1〜C6ハロアルキルスルホニルオキシ、-SH、C1〜C6アルキルチオ、C1〜C6ハロアルキルチオ、C1〜C6アルキルスルフィニル、C1〜C6ハロアルキルスルフィニル、C1〜C6アルキルスルホニル、C1〜C6ハロアルキルスルホニル、-NH2、C1〜C6アルキルアミノ、ジ(C1〜C6アルキル)アミノ、C1〜C6アルキルスルホニルアミノ、C1〜C6ハロアルキルスルホニルアミノ、C1〜C6アルコキシカルボニル、C1〜C6ハロアルコキシカルボニル、-C(O)NH2、C1〜C6アルキルアミノカルボニル、ジ(C1〜C6アルキル)アミノカルボニル、-C(S)NH2、C1〜C6アルキルアミノスルホニル、ジ(C1〜C6アルキル)アミノスルホニル又はトリ(C1〜C6アルキル)シリルを表し、p1, p2, p3又はp4が２以上の整数を表すとき、各々のZは互いに同一であっても又は互いに相異なっていてもよく、
さらに、２つのZが隣接する場合には、隣接する２つのZは-CH2CH2CH2-, -CH2CH2O-, -CH2OCH2-, -OCH2O-, -CH2CH2S-, -CH2SCH2-, -CH2CH2CH2CH2-, -CH2CH2CH2O-, -CH2CH2OCH2-, -CH2OCH2O-, -OCH2CH2O-, -OCH2CH2S-又は-CH=CHCH=CH-を形成することにより、２つのZのそれぞれが結合する炭素原子と共に５員環又は６員環を形成してもよく、このとき、環を形成する各々の炭素原子に結合した水素原子はハロゲン原子又はC1〜C6アルキル基によって任意に置換されていてもよく、
R7は、ハロゲン原子、シアノ、C3〜C8シクロアルキル、C3〜C8ハロシクロアルキル、-OH、-OR8、-SH、-S(O)rR8、-N(R10)R9、-N(R10)CHO、-N(R10)C(O)R9、-N(R10)C(O)OR9、-N(R10)C(O)SR9、-N(R10)C(S)OR9、-N(R10)C(S)SR9、-N(R10)S(O)2R9、-C(O)OR9、-C(O)N(R10)R9、-Si(R13)(R14)R12、フェニル、(Z)p1によって置換されたフェニル、L又はMを表し、
R8は、C1〜C6アルキル、R25によって任意に置換された(C1〜C6)アルキル、C3〜C8シクロアルキル、R25によって任意に置換された(C3〜C8)シクロアルキル、C2〜C6アルケニル、R25によって任意に置換された(C2〜C6)アルケニル、C3〜C8シクロアルケニル、C3〜C8ハロシクロアルケニル、C3〜C6アルキニル、R25によって任意に置換された(C3〜C6)アルキニル、フェニル、(Z)p1によって置換されたフェニル、L又はMを表し、
R9は、C1〜C6アルキル、C1〜C6ハロアルキル、C3〜C6シクロアルキル(C1〜C4)アルキル、C1〜C6アルコキシ(C1〜C4)アルキル、C1〜C6アルキルチオ(C1〜C4)アルキル、シアノ(C1〜C6)アルキル、フェニル(C1〜C4)アルキル、(Z)p1によって置換されたフェニル(C1〜C4)アルキル、L-(C1〜C4)アルキル、M-(C1〜C4)アルキル、C3〜C8シクロアルキル、C3〜C8ハロシクロアルキル、C3〜C6アルケニル、C3〜C6ハロアルケニル、C3〜C6アルキニル、フェニル又は(Z)p1によって置換されたフェニルを表し、
R10は、水素原子又はC1〜C6アルキルを表すか、或いは、R9とR10とが一緒になってC2〜C6アルキレン鎖を形成することにより、結合する原子と共に３〜７員環を形成してもよいことを表し、このときこのアルキレン鎖は酸素原子、硫黄原子又は窒素原子を１個含んでもよく、且つハロゲン原子、C1〜C6アルキル基、C1〜C6アルコキシ基、ホルミル基、C1〜C6アルキルカルボニル基又はC1〜C6アルコキシカルボニル基によって任意に置換されていてもよく、
R11は、水素原子、C1〜C6アルキル、C1〜C6ハロアルキル、フェニル(C1〜C4)アルキル、(Z)p1によって置換されたフェニル(C1〜C4)アルキル、C3〜C6アルケニル、C3〜C6ハロアルケニル、C3〜C6アルキニル又はC3〜C6ハロアルキニルを表すか、或いは、R11はR9と一緒になってC2〜C4アルキレン鎖を形成することにより、結合する原子と共に５〜７員環を形成してもよいことを表し、このときこのアルキレン鎖は酸素原子、硫黄原子又は窒素原子を１個含んでもよく、且つハロゲン原子又はC1〜C6アルキル基によって任意に置換されていてもよく、
R12は、C1〜C6アルキル、C1〜C6ハロアルキル、C3〜C6アルケニル、フェニル又は(Z)p1によって置換されたフェニルを表し、
R13及びR14は、各々独立してC1〜C6アルキル又はC1〜C6ハロアルキルを表し、
R15は、水素原子、C1〜C6アルキル、C1〜C6ハロアルキル、C1〜C6アルコキシカルボニル(C1〜C4)アルキル、C1〜C6ハロアルコキシカルボニル(C1〜C4)アルキル、フェニル(C1〜C4)アルキル、(Z)p1によって置換されたフェニル(C1〜C4)アルキル、C3〜C6アルケニル、C3〜C6ハロアルケニル、C3〜C6アルキニル、C3〜C6ハロアルキニル、C1〜C6アルコキシ、C1〜C6アルコキシカルボニル、C1〜C6ハロアルコキシカルボニル、フェニル又は(Z)p1によって置換されたフェニルを表し、
R16は、ハロゲン原子、シアノ、ニトロ、C3〜C8シクロアルキル、C3〜C8ハロシクロアルキル、-OR26、-N(R27)R26、-SH、-S(O)rR28、-SO2NHR30、-SO2N(R30)R29、-CHO、-C(O)R29、-C(O)OH、-C(O)OR29、-C(O)SR29、-C(O)NHR30、-C(O)N(R30)R29、-C(O)C(O)OR29、-C(R32)=NOH、-C(R32)=NOR31、-Si(R13)(R14)R12、-P(O)(OR22)2、-P(S)(OR22)2、-P(フェニル)2、-P(O)(フェニル)2、フェニル、(Z)p1によって置換されたフェニル、L又はMを表し、
R17は、C1〜C12アルキル、C1〜C12ハロアルキル、C1〜C12アルコキシ(C1〜C12)アルキル、シアノ(C1〜C12)アルキル、C1〜C12アルコキシカルボニル(C1〜C12)アルキル、フェニル(C1〜C4)アルキル、(Z)p1によって置換されたフェニル(C1〜C4)アルキル、C3〜C12アルケニル、C3〜C12ハロアルケニル、C3〜C12アルキニル、C3〜C12ハロアルキニル、C1〜C12アルキルカルボニル、C1〜C12アルコキシカルボニル、フェニル又は(Z)p1によって置換されたフェニルを表し、
R18は、C1〜C12アルキル、C1〜C12ハロアルキル、C1〜C12アルコキシ(C1〜C12)アルキル、シアノ(C1〜C12)アルキル、C1〜C12アルコキシカルボニル(C1〜C12)アルキル、フェニル(C1〜C4)アルキル、(Z)p1によって置換されたフェニル(C1〜C4)アルキル、C3〜C12アルケニル、C3〜C12ハロアルケニル、C3〜C12アルキニル、C3〜C12ハロアルキニル、フェニル又は(Z)p1によって置換されたフェニルを表すか、或いは、R17とR18とが一緒になってC4〜C7アルキレン鎖を形成することにより、結合する窒素原子と共に５〜８員環を形成してもよいことを表し、このときこのアルキレン鎖は酸素原子又は硫黄原子を１個含んでもよく、且つC1〜C4アルキル基又はC1〜C4アルコキシ基によって任意に置換されていてもよく、
R19は、水素原子、C1〜C6アルキル、C1〜C6ハロアルキル、フェニル(C1〜C4)アルキル、(Z)p1によって置換されたフェニル(C1〜C4)アルキル、C3〜C6アルケニル、C3〜C6ハロアルケニル、C3〜C6アルキニル、-CHO、C1〜C6アルキルカルボニル、C1〜C6ハロアルキルカルボニル、C1〜C6アルコキシカルボニル、C1〜C6ハロアルコキシカルボニル、フェニル(C1〜C4)アルコキシカルボニル、(Z)p1によって置換されたフェニル(C1〜C4)アルコキシカルボニル、フェノキシカルボニル、(Z)p1によって置換されたフェノキシカルボニル、フェニルカルボニル、(Z)p1によって置換されたフェニルカルボニル、フェニル又は(Z)p1によって置換されたフェニルを表し、
R20は、水素原子、C1〜C6アルキル、-CHO、C1〜C6アルキルカルボニル、C1〜C6ハロアルキルカルボニル又はC1〜C6アルコキシカルボニルを表し、
R21は、シアノ、C3〜C8シクロアルキル、C3〜C8ハロシクロアルキル、-OH、-OR8、-SH、-S(O)rR8、-N(R10)R9、-N(R10)CHO、-N(R10)C(O)R9、-N(R10)C(O)OR9、-N(R10)C(O)SR9、-N(R10)C(S)OR9、-N(R10)C(S)SR9、-N(R10)S(O)2R9、-C(O)OR9、-C(O)N(R10)R9、-Si(R13)(R14)R12、フェニル、(Z)p1によって置換されたフェニル、L又はMを表し、
R22は、C1〜C6アルキル又はC1〜C6ハロアルキルを表し、
R23は、ハロゲン原子、シアノ、C1〜C6アルキル、C1〜C6ハロアルキル、ヒドロキシ(C1〜C6)アルキル、C1〜C4アルコキシ(C1〜C4)アルキル、C1〜C4アルコキシカルボニル(C1〜C4)アルキル、C1〜C6アルコキシ、C1〜C6アルコキシカルボニル、フェニル又は(Z)p1によって置換されたフェニルを表し、q1, q2, q3又はq4が２以上の整数を表すとき、各々のR23は互いに同一であっても、または互いに相異なっていてもよく、
R24は、水素原子、C1〜C6アルキル、C1〜C6ハロアルキル、-CHO、C1〜C6アルキルカルボニル、C1〜C6ハロアルキルカルボニル、フェニル(C1〜C4)アルキルカルボニル、(Z)p1によって置換されたフェニル(C1〜C4)アルキルカルボニル、C1〜C6アルコキシカルボニル、C1〜C6ハロアルコキシカルボニル、フェニル(C1〜C4)アルコキシカルボニル、(Z)p1によって置換されたフェニル(C1〜C4)アルコキシカルボニル、C1〜C6アルキルチオカルボニル、C1〜C6アルコキシチオカルボニル、C1〜C6アルキルアミノカルボニル、ジ(C1〜C6アルキル)アミノカルボニル、C1〜C6アルキルアミノチオカルボニル、ジ(C1〜C6アルキル)アミノチオカルボニル、フェニルカルボニル、(Z)p1によって置換されたフェニルカルボニル、C1〜C6アルキルスルホニル、C1〜C6ハロアルキルスルホニル、フェニルスルホニル、(Z)p1によって置換されたフェニルスルホニル、-P(O)(OR22)2又は-P(S)(OR22)2を表し、
R25は、ハロゲン原子、シアノ、C3〜C8シクロアルキル、C3〜C8ハロシクロアルキル、C1〜C6アルコキシ、C1〜C6ハロアルコキシ、C1〜C6アルキルチオ、C1〜C6ハロアルキルチオ、C1〜C6アルキルスルホニル、C1〜C6ハロアルキルスルホニル、C1〜C6アルキルアミノ、ジ(C1〜C6アルキル)アミノ、-CHO、C1〜C6アルキルカルボニル、C1〜C6ハロアルキルカルボニル、C1〜C6アルコキシカルボニル、C1〜C6ハロアルコキシカルボニル、-CH=NOR11、-C(R9)=NOR11、フェニル、(Z)p1によって置換されたフェニル、L又はMを表し、
R26は、水素原子、C1〜C8アルキル、R33によって任意に置換された(C1〜C8)アルキル、C3〜C8シクロアルキル、R33によって任意に置換された(C3〜C8)シクロアルキル、C3〜C8アルケニル、R33によって任意に置換された(C3〜C8)アルケニル、C3〜C8アルキニル、R33によって任意に置換された(C3〜C8)アルキニル、-CHO、-C(O)R29、-C(O)OR29、-C(O)SR29、-C(O)NHR30、-C(O)N(R30)R29、-C(O)C(O)R29、-C(O)C(O)OR29、-C(S)R29、-C(S)OR29、-C(S)SR29、-C(S)NHR30、-C(S)N(R30)R29、-S(O)2R29、-S(O)2N(R30)R29、-Si(R13)(R14)R12、-P(O)(OR22)2、-P(S)(OR22)2、フェニル、(Z)p1によって置換されたフェニル、L又はMを表し、
R27は、水素原子、C1〜C6アルキル、C1〜C6ハロアルキル、C3〜C6シクロアルキル又はC1〜C6アルコキシを表すか、或いは、R26とR27とが一緒になってC2〜C5アルキレン鎖を形成することにより、結合する窒素原子と共に３〜６員環を形成してもよいことを表し、このときこのアルキレン鎖は酸素原子又は硫黄原子を１個含んでもよく、且つハロゲン原子、C1〜C6アルキル基、C1〜C6アルコキシ基、フェニル基又は(Z)p1によって置換されたフェニル基によって置換されていてもよく、
R28は、C1〜C8アルキル、R33によって任意に置換された(C1〜C8)アルキル、C3〜C8シクロアルキル、R33によって任意に置換された(C3〜C8)シクロアルキル、C3〜C8アルケニル、R33によって任意に置換された(C3〜C8)アルケニル、C3〜C8アルキニル、R33によって任意に置換された(C3〜C8)アルキニル、-SH、C1〜C6アルキルチオ、C1〜C6ハロアルキルチオ、フェニルチオ、(Z)p1によって置換されたフェニルチオ、-CHO、-C(O)R29、-C(O)OR29、-C(O)SR29、-C(O)NHR30、-C(O)N(R30)R29、-C(O)C(O)R29、-C(O)C(O)OR29、-C(S)R29、-C(S)OR29、-C(S)SR29、-C(S)NHR30、-C(S)N(R30)R29、-P(O)(OR22)2、-P(S)(OR22)2、フェニル、(Z1)p1によって置換されたフェニル、L-18、L-21、L-25、L-30〜L-35、L-45、L-48、L-49又はMを表し、
R29は、C1〜C6アルキル、C1〜C6ハロアルキル、C3〜C8シクロアルキル(C1〜C4)アルキル、C1〜C6アルコキシ(C1〜C4)アルキル、C1〜C6ハロアルコキシ(C1〜C4)アルキル、C1〜C6アルキルチオ(C1〜C4)アルキル、C1〜C6ハロアルキルチオ(C1〜C4)アルキル、C1〜C6アルキルスルホニル(C1〜C4)アルキル、C1〜C6ハロアルキルスルホニル(C1〜C4)アルキル、シアノ(C1〜C6)アルキル、C1〜C6アルキルカルボニル(C1〜C4)アルキル、C1〜C6ハロアルキルカルボニル(C1〜C4)アルキル、C1〜C6アルコキシカルボニル(C1〜C4)アルキル、ジ(C1〜C6アルキル)アミノカルボニル(C1〜C4)アルキル、トリ(C1〜C4アルキル)シリル(C1〜C4)アルキル、フェニル(C1〜C4)アルキル、(Z)p1によって置換されたフェニル(C1〜C4)アルキル、L-(C1〜C4)アルキル、M-(C1〜C4)アルキル、C3〜C8シクロアルキル、C3〜C8ハロシクロアルキル、C2〜C6アルケニル、C2〜C6ハロアルケニル、C2〜C6アルキニル、C2〜C6ハロアルキニル、フェニル、(Z)p1によって置換されたフェニル、L又はMを表し、
R30は、水素原子、C1〜C6アルキル、C1〜C6ハロアルキル、フェニル又は(Z)p1によって置換されたフェニルを表すか、或いは、R29とR30とが一緒になってC2〜C5アルキレン鎖を形成することにより、結合する窒素原子と共に３〜６員環を形成してもよいことを表し、このときこのアルキレン鎖は酸素原子、硫黄原子又は窒素原子を１個含んでもよく、且つハロゲン原子、C1〜C6アルキル基、C1〜C6アルコキシ基、ホルミル基、C1〜C6アルキルカルボニル基、C1〜C6アルコキシカルボニル基、フェニル基又は(Z)p1によって置換されたフェニル基によって任意に置換されていてもよく、
R31は、水素原子、C1〜C8アルキル、R33によって任意に置換された(C1〜C8)アルキル、C3〜C8シクロアルキル、C3〜C8アルケニル、R33によって任意に置換された(C3〜C8)アルケニル、C3〜C8アルキニル又はR33によって任意に置換された(C3〜C8)アルキニルを表し、
R32は、水素原子、C1〜C6アルキル、C1〜C6ハロアルキル、C3〜C8シクロアルキル(C1〜C4)アルキル、C1〜C6アルコキシ(C1〜C4)アルキル、C1〜C6ハロアルコキシ(C1〜C4)アルキル、C1〜C6アルキルチオ(C1〜C4)アルキル、C1〜C6ハロアルキルチオ(C1〜C4)アルキル、C1〜C6アルキルスルホニル(C1〜C4)アルキル、C1〜C6ハロアルキルスルホニル(C1〜C4)アルキル、フェニル(C1〜C4)アルキル、(Z)p1によって置換されたフェニル(C1〜C4)アルキル、フェニル又は(Z)p1によって置換されたフェニルを表し、
R33は、ハロゲン原子、シアノ、ニトロ、C3〜C8シクロアルキル、C3〜C8ハロシクロアルキル、-OH、-OR34、-SH、-S(O)rR34、-NHR35、-N(R35)R34、-CHO、-C(O)R29、-C(O)OR29、-C(O)SR29、-C(O)NHR30、-C(O)N(R30)R29、-C(O)C(O)OR29、-CH=NOR11、-C(R9)=NOR11、-Si(R13)(R14)R12、-P(O)(OR22)2、-P(S)(OR22)2、-P(フェニル)2、-P(O)(フェニル)2、フェニル、(Z)p1によって置換されたフェニル、L又はMを表し、
R34は、C1〜C6アルキル、C1〜C6ハロアルキル、C1〜C6アルコキシ(C1〜C4)アルキル、C1〜C6アルキルチオ(C1〜C4)アルキル、フェニル(C1〜C4)アルキル、(Z)p1によって置換されたフェニル(C1〜C4)アルキル、C3〜C8シクロアルキル、C3〜C8ハロシクロアルキル、C3〜C6アルケニル、C3〜C6ハロアルケニル、C3〜C8シクロアルケニル、C3〜C8ハロシクロアルケニル、C3〜C6アルキニル、C3〜C6ハロアルキニル、-CHO、C1〜C6アルキルカルボニル、C1〜C6ハロアルキルカルボニル、C1〜C6アルコキシカルボニル、C1〜C6ハロアルコキシカルボニル、C1〜C6アルキルアミノカルボニル、ジ(C1〜C6アルキル)アミノカルボニル、フェニルカルボニル、(Z)p1によって置換されたフェニルカルボニル、C1〜C6アルキルアミノチオカルボニル、ジ(C1〜C6アルキル)アミノチオカルボニル、フェニル、(Z)p1によって置換されたフェニル、L又はMを表し、
R35は、水素原子、C1〜C6アルキル、C1〜C6ハロアルキル、C3〜C8シクロアルキル、C3〜C6アルケニル、C3〜C6アルキニル、C1〜C6アルキルカルボニル、C1〜C6ハロアルキルカルボニル、C1〜C6アルコキシカルボニル、C1〜C6ハロアルコキシカルボニル、フェノキシカルボニル、(Z)p1によって置換されたフェノキシカルボニル、フェニルカルボニル、(Z)p1によって置換されたフェニルカルボニル、C1〜C6アルキルスルホニル、C1〜C6ハロアルキルスルホニル、フェニル、(Z)p1によって置換されたフェニル、L又はMを表すか、或いは、R34とR35とが一緒になってC2〜C5アルキレン鎖を形成することにより、結合する窒素原子と共に３〜６員環を形成してもよいことを表し、このときこのアルキレン鎖は酸素原子又は硫黄原子を１個含んでもよく、且つハロゲン原子又はメチル基によって置換されていてもよく、
mは、０〜４の整数を表し、
nは、０〜４の整数を表し、
p1は、１〜５の整数を表し、
p2は、０〜４の整数を表し、
p3は、０〜３の整数を表し、
p4は、０〜２の整数を表し、
p5は、０又は１の整数を表し、
q1は、０〜３の整数を表し、
q2は、０〜５の整数を表し、
q3は、０〜７の整数を表し、
q4は、０〜９の整数を表し、
rは、０〜２の整数を表し、
tは、０又は１の整数を表す。］
で表される置換ベンズアニリド化合物又はその塩。 Z is a halogen atom, cyano, nitro, azido, -SCN, -SF 5, C 1 ~C 6 alkyl, C 1 -C 6 haloalkyl, C 1 -C 3 alkoxy (C 1 ~C 3) alkyl, C 1 -C 3 haloalkoxy (C 1 ~C 3) alkyl, cyano (C 1 ~C 6) alkyl, hydroxy (C 1 ~C 3) haloalkyl, C 1 -C 3 alkoxy (C 1 ~C 3) haloalkyl, C 1 -C 3 haloalkoxy (C 1 ~C 3) haloalkyl, C 1 -C 3 alkylthio (C 1 ~C 3) alkyl, C 1 -C 3 haloalkylthio (C 1 ~C 3) alkyl, C 1 -C 3 alkylsulfinyl (C 1 -C 3) alkyl, C 1 -C 3 haloalkylsulfinyl (C 1 -C 3) alkyl, C 1 -C 3 alkylsulfonyl (C 1 -C 3) alkyl, C 1 -C 3 haloalkyl sulfonyl (C 1 ~C 3) alkyl, C 3 -C 8 cycloalkyl, C 3 -C 8 halocycloalkyl, C 2 -C 6 alkenyl, C 2 -C 6 haloalkenyl, C 3 -C 8 Cycloalkenyl, C 3 -C 8 halocycloalkyl cycloalkenyl, C 2 -C 6 alkynyl, C 2 -C 6 haloalkynyl, -OH, C 1 ~C 6 alkoxy, C 1 -C 6 haloalkoxy, C 1 -C 3 haloalkoxy (C 1 ~C 3) haloalkoxy, C 2 -C 6 alkenyloxy, C 2 -C 6 haloalkenyloxy, C 3 -C 6 alkynyloxy, C 3 -C 6 haloalkynyloxy, C 1 -C 6 alkylsulfonyloxy, C 1 -C 6 haloalkylsulfonyloxy, -SH, C 1 ~C 6 alkylthio, C 1 -C 6 haloalkylthio, C 1 -C 6 alkylsulfinyl, C 1 -C 6 haloalkylsulfinyl, C 1 -C 6 alkylsulfonyl, C 1 -C 6 haloalkylsulfonyl, -NH 2, C 1 ~C 6 alkyl amino, di (C 1 -C 6 alkyl) amino, C 1 -C 6 alkylsulfonylamino, C 1 -C 6 haloalkylsulfonyl amino, C 1 -C 6 an alkoxycarbonyl Boniru, C 1 -C 6 haloalkoxycarbonyl, -C (O) NH 2, C 1 ~C 6 alkylaminocarbonyl, di (C 1 -C 6 alkyl) aminocarbonyl, -C (S) NH 2, C 1 -C 6 alkylaminosulfonyl, di (C 1 -C 6 alkyl) aminosulfonyl or a tri (C 1 -C 6 alkyl) a silyl, when p1, p2, p3 or p4 represents an integer of 2 or more, each of the Z may be the same as or different from each other,
Further, when two Zs are adjacent to each other, the two adjacent Zs are -CH 2 CH 2 CH 2- , -CH 2 CH 2 O-, -CH 2 OCH 2- , -OCH 2 O-, -CH 2 CH 2 S-, -CH 2 SCH 2- , -CH 2 CH 2 CH 2 CH 2 CH 2- , -CH 2 CH 2 CH 2 O-, -CH 2 CH 2 OCH 2- , -CH 2 OCH 2 O- , -OCH 2 CH 2 O-, -OCH 2 CH 2 S- or -CH = CHCH = CH- to form a 5-membered or 6-membered ring with the carbon atom to which each of the two Z bonds may be, at this time, the hydrogen atoms bonded to each carbon atom forming the ring may be optionally substituted by halogen atom or C 1 -C 6 alkyl group,
R 7 is a halogen atom, cyano, C 3 to C 8 cycloalkyl, C 3 to C 8 halocycloalkyl, —OH, —OR 8 , —SH, —S (O) r R 8 , —N (R 10 ) R 9 , -N (R 10 ) CHO, -N (R 10 ) C (O) R 9 , -N (R 10 ) C (O) OR 9 , -N (R 10 ) C (O) SR 9 , -N (R 10 ) C (S) OR 9 , -N (R 10 ) C (S) SR 9 , -N (R 10 ) S (O) 2 R 9 , -C (O) OR 9 ,- C (O) N (R 10 ) R 9 , -Si (R 13 ) (R 14 ) R 12 , phenyl, (Z) represents phenyl, L or M substituted by p1 ;
R 8 is optionally substituted by C 1 -C 6 alkyl, optionally substituted by R 25 (C 1 ~C 6) alkyl, C 3 -C 8 cycloalkyl, R 25 (C 3 ~C 8 ) cycloalkyl, C 2 -C 6 alkenyl, optionally substituted by R 25 (C 2 ~C 6) alkenyl, C 3 -C 8 cycloalkenyl, C 3 -C 8 halocycloalkyl cycloalkenyl, C 3 -C 6 It represents alkynyl, optionally substituted by R 25 (C 3 ~C 6) alkynyl, phenyl, phenyl, L or M, which is substituted by (Z) p1,
R 9 is C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, C 3 -C 6 cycloalkyl (C 1 -C 4 ) alkyl, C 1 -C 6 alkoxy (C 1 -C 4 ) alkyl, C 1 -C 6 alkylthio (C 1 ~C 4) alkyl, cyano (C 1 ~C 6) alkyl, phenyl (C 1 ~C 4) alkyl, (Z) phenyl substituted by p1 (C 1 ~C 4) Alkyl, L- (C 1 -C 4 ) alkyl, M- (C 1 -C 4 ) alkyl, C 3 -C 8 cycloalkyl, C 3 -C 8 halocycloalkyl, C 3 -C 6 alkenyl, C 3 -C 6 represents haloalkenyl, C 3 -C 6 alkynyl, phenyl substituted by phenyl or (Z) p1,
R 10 represents a hydrogen atom or C 1 -C 6 alkyl, or R 9 and R 10 together form a C 2 -C 6 alkylene chain to form 3-7 together with the atoms to be bonded. indicates that the members may form a ring, this time the alkylene chain an oxygen atom, may contain one sulfur atom or a nitrogen atom, and a halogen atom, C 1 -C 6 alkyl group, C 1 -C 6 alkoxy group, a formyl group, may be optionally substituted by C 1 -C 6 alkylcarbonyl group or a C 1 -C 6 alkoxycarbonyl group,
R 11 represents a hydrogen atom, C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, phenyl (C 1 ~C 4) alkyl, (Z) phenyl substituted by p1 (C 1 ~C 4) alkyl, C 3 -C 6 alkenyl, C 3 -C 6 haloalkenyl, or represents C 3 -C 6 alkynyl or C 3 -C 6 haloalkynyl, or, R 11 is C 2 -C 4 alkylene together with R 9 By forming a chain, it represents that a 5- to 7-membered ring may be formed together with the atoms to be bonded. At this time, the alkylene chain may contain one oxygen atom, sulfur atom or nitrogen atom, and a halogen atom. or it may be optionally substituted by C 1 -C 6 alkyl group,
R 12 represents C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, C 3 -C 6 alkenyl, phenyl or phenyl substituted by (Z) p1 ;
R 13 and R 14 each independently represent C 1 -C 6 alkyl or C 1 -C 6 haloalkyl,
R 15 is a hydrogen atom, C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, C 1 -C 6 alkoxycarbonyl (C 1 -C 4 ) alkyl, C 1 -C 6 haloalkoxycarbonyl (C 1 -C 4) alkyl, phenyl (C 1 -C 4) alkyl, (Z) phenyl substituted by p1 (C 1 -C 4) alkyl, C 3 -C 6 alkenyl, C 3 -C 6 haloalkenyl, C 3 ~ C 6 represents alkynyl, C 3 -C 6 haloalkynyl, C 1 -C 6 alkoxy, C 1 -C 6 alkoxycarbonyl, C 1 -C 6 haloalkoxycarbonyl, phenyl substituted by phenyl or (Z) p1,
R 16 is a halogen atom, cyano, nitro, C 3 -C 8 cycloalkyl, C 3 -C 8 halocycloalkyl, -OR 26 , -N (R 27 ) R 26 , -SH, -S (O) r R 28 , -SO 2 NHR 30 , -SO 2 N (R 30 ) R 29 , -CHO, -C (O) R 29 , -C (O) OH, -C (O) OR 29 , -C (O ) SR 29 , -C (O) NHR 30 , -C (O) N (R 30 ) R 29 , -C (O) C (O) OR 29 , -C (R 32 ) = NOH, -C (R 32 ) = NOR 31 , -Si (R 13 ) (R 14 ) R 12 , -P (O) (OR 22 ) 2 , -P (S) (OR 22 ) 2 , -P (phenyl) 2 , -P (O) (phenyl) 2 , phenyl, (Z) represents phenyl, L or M substituted by p1 ,
R 17 is C 1 -C 12 alkyl, C 1 -C 12 haloalkyl, C 1 -C 12 alkoxy (C 1 -C 12 ) alkyl, cyano (C 1 -C 12 ) alkyl, C 1 -C 12 alkoxycarbonyl (C 1 ~C 12) alkyl, phenyl (C 1 ~C 4) alkyl, (Z) phenyl substituted by p1 (C 1 ~C 4) alkyl, C 3 -C 12 alkenyl, C 3 -C 12 halo represents alkenyl, C 3 -C 12 alkynyl, C 3 -C 12 haloalkynyl, C 1 -C 12 alkylcarbonyl, C 1 -C 12 alkoxycarbonyl, phenyl substituted by phenyl or (Z) p1,
R 18 is C 1 -C 12 alkyl, C 1 -C 12 haloalkyl, C 1 -C 12 alkoxy (C 1 -C 12 ) alkyl, cyano (C 1 -C 12 ) alkyl, C 1 -C 12 alkoxycarbonyl (C 1 ~C 12) alkyl, phenyl (C 1 ~C 4) alkyl, (Z) phenyl substituted by p1 (C 1 ~C 4) alkyl, C 3 -C 12 alkenyl, C 3 -C 12 halo alkenyl, C 3 -C 12 alkynyl, C 3 -C 12 haloalkynyl, or represents phenyl which is substituted by phenyl or (Z) p1, or, C 4 -C 7 and R 17 and R 18 together By forming an alkylene chain, it represents that a 5- to 8-membered ring may be formed together with the nitrogen atom to be bonded. At this time, the alkylene chain may contain one oxygen atom or sulfur atom, and C 1- It may be optionally substituted by C 4 alkyl group or a C 1 -C 4 alkoxy group,
R 19 is a hydrogen atom, C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, phenyl (C 1 ~C 4) alkyl, (Z) phenyl substituted by p1 (C 1 ~C 4) alkyl, C 3 -C 6 alkenyl, C 3 -C 6 haloalkenyl, C 3 -C 6 alkynyl, -CHO, C 1 ~C 6 alkyl carbonyl, C 1 -C 6 haloalkylcarbonyl, C 1 -C 6 alkoxycarbonyl, C 1 -C 6 haloalkoxycarbonyl, phenyl (C 1 ~C 4) alkoxycarbonyl, (Z) phenyl substituted by p1 (C 1 ~C 4) alkoxycarbonyl, phenoxycarbonyl, phenoxycarbonyl substituted by (Z) p1 , Phenylcarbonyl, phenylcarbonyl substituted by (Z) p1 , phenyl or phenyl substituted by (Z) p1 ,
R 20 represents a hydrogen atom, C 1 -C 6 alkyl, -CHO, C 1 -C 6 alkylcarbonyl, a C 1 -C 6 haloalkylcarbonyl or C 1 -C 6 alkoxycarbonyl,
R 21 is cyano, C 3 to C 8 cycloalkyl, C 3 to C 8 halocycloalkyl, —OH, —OR 8 , —SH, —S (O) r R 8 , —N (R 10 ) R 9 , -N (R 10 ) CHO, -N (R 10 ) C (O) R 9 , -N (R 10 ) C (O) OR 9 , -N (R 10 ) C (O) SR 9 , -N (R 10 ) C (S) OR 9 , -N (R 10 ) C (S) SR 9 , -N (R 10 ) S (O) 2 R 9 , -C (O) OR 9 , -C (O ) N (R 10 ) R 9 , -Si (R 13 ) (R 14 ) R 12 , phenyl, (Z) represents phenyl, L or M substituted by p1 ;
R 22 represents C 1 -C 6 alkyl or C 1 -C 6 haloalkyl,
R 23 is a halogen atom, cyano, C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, hydroxy (C 1 -C 6 ) alkyl, C 1 -C 4 alkoxy (C 1 -C 4 ) alkyl, C 1 -C 4 alkoxycarbonyl (C 1 ~C 4) represents alkyl, C 1 -C 6 alkoxy, C 1 -C 6 alkoxycarbonyl, phenyl substituted by phenyl or (Z) p1, q1, q2 , q3 or q4 When each represents an integer of 2 or more, each R 23 may be the same as or different from each other;
R 24 is a hydrogen atom, C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, -CHO, C 1 -C 6 alkylcarbonyl, C 1 -C 6 haloalkylcarbonyl, phenyl (C 1 ~C 4) alkylcarbonyl (Z) phenyl (C 1 -C 4 ) alkylcarbonyl, C 1 -C 6 alkoxycarbonyl, C 1 -C 6 haloalkoxycarbonyl, phenyl (C 1 -C 4 ) alkoxycarbonyl, substituted by p1 (Z ) phenyl substituted by p1 (C 1 ~C 4) alkoxycarbonyl, C 1 -C 6 alkylthiocarbonyl, C 1 -C 6 alkoxythiocarbonyl, C 1 -C 6 alkylaminocarbonyl, di (C 1 -C 6 alkyl) aminocarbonyl, C 1 -C 6 alkylamino thiocarbonyl, di (C 1 -C 6 alkyl) aminothiocarbonyl, phenylcarbonyl, (Z) phenylcarbonyl substituted by p1, C 1 -C 6 alkyl sulfonyl Represents C 1 -C 6 haloalkylsulfonyl, phenylsulfonyl, and (Z) phenylsulfonyl substituted by p1, -P (O) (OR 22) 2 or -P (S) (OR 22) 2,
R 25 is a halogen atom, cyano, C 3 -C 8 cycloalkyl, C 3 -C 8 halocycloalkyl, C 1 -C 6 alkoxy, C 1 -C 6 haloalkoxy, C 1 -C 6 alkylthio, C 1 -C 6 haloalkylthio, C 1 -C 6 alkylsulfonyl, C 1 -C 6 haloalkylsulfonyl, C 1 -C 6 alkylamino, di (C 1 -C 6 alkyl) amino, -CHO, C 1 -C 6 alkyl carbonyl, C 1 -C 6 haloalkylcarbonyl, C 1 -C 6 alkoxycarbonyl, C 1 -C 6 haloalkoxycarbonyl, -CH = NOR 11, -C ( R 9) = NOR 11, phenyl, the (Z) p1 Represents substituted phenyl, L or M;
R 26 is a hydrogen atom, C 1 -C 8 alkyl, optionally substituted by R 33 (C 1 ~C 8) alkyl, C 3 -C 8 cycloalkyl, optionally substituted by R 33 (C 3 -C 8) cycloalkyl, C 3 -C 8 alkenyl, optionally substituted by R 33 (C 3 ~C 8) alkenyl, optionally substituted by C 3 -C 8 alkynyl, R 33 (C 3 ~ C 8 ) alkynyl, -CHO, -C (O) R 29 , -C (O) OR 29 , -C (O) SR 29 , -C (O) NHR 30 , -C (O) N (R 30 ) R 29 , -C (O) C (O) R 29 , -C (O) C (O) OR 29 , -C (S) R 29 , -C (S) OR 29 , -C (S) SR 29 , -C (S) NHR 30 , -C (S) N (R 30 ) R 29 , -S (O) 2 R 29 , -S (O) 2 N (R 30 ) R 29 , -Si (R 13 ) (R 14 ) R 12 , -P (O) (OR 22 ) 2 , -P (S) (OR 22 ) 2 , phenyl, (Z) represents phenyl, L or M substituted by p1 ;
R 27 represents a hydrogen atom, C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, C 3 -C 6 cycloalkyl or C 1 -C 6 alkoxy, or R 26 and R 27 together by now it forms a C 2 -C 5 alkylene chain, represents that may form a 3-6 membered ring together with the nitrogen atom to which they are attached this case the alkylene chain may contain one oxygen atom or a sulfur atom But often, and halogen atom, C 1 -C 6 alkyl group, C 1 -C 6 alkoxy group, a phenyl group or (Z) p1 may be substituted by a phenyl group substituted by,
R 28 is, C 1 -C 8 alkyl, optionally substituted by R 33 (C 1 ~C 8) alkyl, optionally substituted by C 3 -C 8 cycloalkyl, R 33 (C 3 ~C 8 ) cycloalkyl, optionally substituted by C 3 -C 8 alkenyl, R 33 (C 3 ~C 8 ) alkenyl, optionally substituted by C 3 -C 8 alkynyl, R 33 (C 3 ~C 8 ) alkynyl, -SH, C 1 -C 6 alkylthio, C 1 -C 6 haloalkylthio, phenylthio, phenylthio substituted by (Z) p1, -CHO, -C (O) R 29, -C (O) OR 29 , -C (O) SR 29 , -C (O) NHR 30 , -C (O) N (R 30 ) R 29 , -C (O) C (O) R 29 , -C (O) C (O ) OR 29 , -C (S) R 29 , -C (S) OR 29 , -C (S) SR 29 , -C (S) NHR 30 , -C (S) N (R 30 ) R 29 ,- P (O) (OR 22 ) 2 , -P (S) (OR 22 ) 2 , phenyl, phenyl substituted by (Z 1 ) p1 , L-18, L-21, L-25, L-30 ~ Represents L-35, L-45, L-48, L-49 or M;
R 29 is C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, C 3 -C 8 cycloalkyl (C 1 -C 4 ) alkyl, C 1 -C 6 alkoxy (C 1 -C 4 ) alkyl, C 1 -C 6 haloalkoxy (C 1 ~C 4) alkyl, C 1 -C 6 alkylthio (C 1 ~C 4) alkyl, C 1 -C 6 haloalkylthio (C 1 ~C 4) alkyl, C 1 -C 6 alkylsulfonyl (C 1 ~C 4) alkyl, C 1 -C 6 haloalkylsulfonyl (C 1 ~C 4) alkyl, cyano (C 1 -C 6) alkyl, C 1 -C 6 alkylcarbonyl (C 1 -C 4) alkyl, C 1 -C 6 haloalkylcarbonyl (C 1 -C 4) alkyl, C 1 -C 6 alkoxycarbonyl (C 1 -C 4) alkyl, di (C 1 -C 6 alkyl) aminocarbonyl (C 1 -C 4) alkyl, tri (C 1 -C 4 alkyl) silyl (C 1 -C 4) alkyl, phenyl (C 1 -C 4) alkyl, phenyl substituted by (Z) p1 (C 1 ~C 4 ) alkyl, L- (C 1 C 4) alkyl, M- (C 1 ~C 4) alkyl, C 3 -C 8 cycloalkyl, C 3 -C 8 halocycloalkyl, C 2 -C 6 alkenyl, C 2 -C 6 haloalkenyl, C 2 -C 6 alkynyl, C 2 -C 6 haloalkynyl, represents phenyl, phenyl, L or M, which is substituted by (Z) p1,
R 30 represents a hydrogen atom, C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, phenyl or phenyl substituted by (Z) p 1 , or R 29 and R 30 together represent C By forming a 2 to C 5 alkylene chain, it represents that a 3 to 6 membered ring may be formed together with the nitrogen atom to be bonded. At this time, this alkylene chain contains one oxygen atom, sulfur atom or nitrogen atom. But often, and halogen atom, C 1 -C 6 alkyl group, C 1 -C 6 alkoxy group, a formyl group, C 1 -C 6 alkylcarbonyl group, C 1 -C 6 alkoxycarbonyl group, a phenyl group or (Z) optionally substituted by a phenyl group substituted by p1 ,
R 31 is hydrogen atom, C 1 -C 8 alkyl, (C 1 -C 8 ) alkyl optionally substituted by R 33 , C 3 -C 8 cycloalkyl, C 3 -C 8 alkenyl, optional by R 33 substituted a (C 3 ~C 8) alkenyl, optionally substituted by C 3 -C 8 alkynyl, or R 33 (C 3 ~C 8) alkynyl,
R 32 is a hydrogen atom, C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, C 3 -C 8 cycloalkyl (C 1 ~C 4) alkyl, C 1 -C 6 alkoxy (C 1 ~C 4) alkyl, C 1 -C 6 haloalkoxy (C 1 ~C 4) alkyl, C 1 -C 6 alkylthio (C 1 ~C 4) alkyl, C 1 -C 6 haloalkylthio (C 1 ~C 4) alkyl, C 1 -C 6 alkylsulfonyl (C 1 ~C 4) alkyl, C 1 -C 6 haloalkylsulfonyl (C 1 ~C 4) alkyl, phenyl (C 1 ~C 4) alkyl, phenyl substituted by (Z) p1 (C 1 ~C 4) represents alkyl, phenyl substituted by phenyl or (Z) p1,
R 33 is a halogen atom, cyano, nitro, C 3 -C 8 cycloalkyl, C 3 -C 8 halocycloalkyl, —OH, —OR 34 , —SH, —S (O) r R 34 , —NHR 35 , -N (R 35 ) R 34 , -CHO, -C (O) R 29 , -C (O) OR 29 , -C (O) SR 29 , -C (O) NHR 30 , -C (O) N (R 30 ) R 29 , -C (O) C (O) OR 29 , -CH = NOR 11 , -C (R 9 ) = NOR 11 , -Si (R 13 ) (R 14 ) R 12 ,- P (O) (OR 22 ) 2 , -P (S) (OR 22 ) 2 , -P (phenyl) 2 , -P (O) (phenyl) 2 , phenyl, phenyl substituted by (Z) p1 , L or M represents
R 34 is C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, C 1 -C 6 alkoxy (C 1 -C 4 ) alkyl, C 1 -C 6 alkylthio (C 1 -C 4 ) alkyl, phenyl ( C 1 -C 4) alkyl, (Z) phenyl substituted by p1 (C 1 ~C 4) alkyl, C 3 -C 8 cycloalkyl, C 3 -C 8 halocycloalkyl, C 3 -C 6 alkenyl, C 3 -C 6 haloalkenyl, C 3 -C 8 cycloalkenyl, C 3 -C 8 halocycloalkyl cycloalkenyl, C 3 -C 6 alkynyl, C 3 -C 6 haloalkynyl, -CHO, C 1 ~C 6 alkyl carbonyl , C 1 -C 6 haloalkylcarbonyl, C 1 -C 6 alkoxycarbonyl, C 1 -C 6 haloalkoxycarbonyl, C 1 -C 6 alkylaminocarbonyl, di (C 1 -C 6 alkyl) aminocarbonyl, phenylcarbonyl, (Z) phenylcarbonyl substituted by p1, C 1 ~C 6 alkylaminothiocarbonyl It represents di (C 1 -C 6 alkyl) aminothiocarbonyl, phenyl, phenyl, L or M, which is substituted by (Z) p1,
R 35 represents a hydrogen atom, C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, C 3 -C 8 cycloalkyl, C 3 -C 6 alkenyl, C 3 -C 6 alkynyl, C 1 -C 6 alkylcarbonyl , C 1 -C 6 haloalkylcarbonyl, C 1 -C 6 alkoxycarbonyl, C 1 -C 6 haloalkoxycarbonyl, phenoxycarbonyl, phenoxycarbonyl substituted by (Z) p1, phenylcarbonyl, substituted by (Z) p1 phenylcarbonyl, C 1 -C 6 alkylsulfonyl and, C 1 -C 6 haloalkylsulfonyl, phenyl, phenyl substituted by (Z) p1, or represents L or M, or the R 34 and R 35 together form by now it forms a C 2 -C 5 alkylene chain, represents that may form a 3-6 membered ring together with the nitrogen atom to which they are attached this case the alkylene chain may contain one oxygen atom or a sulfur atom so May, be substituted and the halogen atom or a methyl group,
m represents an integer of 0 to 4,
n represents an integer of 0 to 4,
p1 represents an integer of 1 to 5,
p2 represents an integer of 0 to 4,
p3 represents an integer of 0 to 3,
p4 represents an integer of 0 to 2,
p5 represents an integer of 0 or 1,
q1 represents an integer of 0 to 3,
q2 represents an integer of 0 to 5,
q3 represents an integer of 0 to 7,
q4 represents an integer of 0 to 9,
r represents an integer of 0 to 2;
t represents an integer of 0 or 1. ]
The substituted benzanilide compound or its salt represented by these.

〔２〕 W1及びW2は、酸素原子を表し、
Xは、ハロゲン原子、シアノ、ニトロ、C1〜C6アルキル、C1〜C6ハロアルキル、C1〜C6アルコキシ、C1〜C6ハロアルコキシ、C1〜C6アルキルスルホニルオキシ、C1〜C6ハロアルキルスルホニルオキシ、C1〜C6アルキルチオ、C1〜C6ハロアルキルチオ、C1〜C6アルキルスルフィニル、C1〜C6ハロアルキルスルフィニル、C1〜C6アルキルスルホニル又はC1〜C6ハロアルキルスルホニルを表し、mが２又は３を表すとき、各々のXは互いに同一であっても又は互いに相異なっていてもよく、
さらに、２つのXが隣接する場合には、隣接する２つのXは-OCH2O-又は-OCH2CH2O-を形成することにより、それぞれが結合する炭素原子と共に５員環又は６員環を形成してもよく、このとき、環を形成する各々の炭素原子に結合した水素原子はハロゲン原子、C1〜C4アルキル基又はC1〜C4ハロアルキル基によって任意に置換されていてもよく、
Yは、ハロゲン原子、C1〜C6アルキル、C1〜C6ハロアルキル、ヒドロキシ(C1〜C6)アルキル、C1〜C3アルコキシ(C1〜C3)アルキル、C1〜C6アルコキシ、C1〜C6ハロアルコキシ、C1〜C6アルキルチオ、C1〜C6ハロアルキルチオ、C1〜C6アルキルアミノ又はジ(C1〜C6アルキル)アミノを表し、nが２又は３を表すとき、各々のYは互いに同一であっても又は互いに相異なっていてもよく、
R1は、C1〜C8アルキル、R16によって任意に置換された(C1〜C8)アルキル、C3〜C8シクロアルキル、C3〜C8アルケニル、C3〜C8アルキニル、C1〜C8アルコキシ、M-4、M-5、M-8、M-9、M-13〜M-19、M-21又はM-22を表し、
R2及びR3は、各々独立して水素原子、C1〜C6アルキル、C1〜C4アルコキシ(C1〜C4)アルキル、C1〜C4アルキルチオ(C1〜C4)アルキル、C1〜C4アルキルスルホニル(C1〜C4)アルキル、C3〜C6アルケニル、C3〜C6アルキニル、C1〜C6アルキルチオ、C1〜C6ハロアルキルチオ、フェニルチオ、(Z)p1によって置換されたフェニルチオ又は-SN(R18)R17を表すか、或いは、R2はR1と一緒になってC2〜C6アルキレン鎖を形成することにより、結合する窒素原子と共に３〜７員環を形成してもよいことを表し、このときこのアルキレン鎖は酸素原子又は硫黄原子を１個含んでもよく、
R4は、C1〜C6アルキル、C1〜C6ハロアルキル、R21によって任意に置換された(C1〜C6)アルキル、R21によって任意に置換された(C1〜C6)ハロアルキル、C3〜C8シクロアルキル、C3〜C8ハロシクロアルキル、C3〜C6ハロアルケニル、C3〜C6ハロアルキニル、フェニル又は(Z)p1によって置換されたフェニルを表し、
R5は、シアノ、R21によって任意に置換された(C1〜C6)アルキル、R21によって任意に置換された(C1〜C6)ハロアルキル、C3〜C8シクロアルキル、C3〜C8ハロシクロアルキル、R21によって任意に置換された(C2〜C6)アルケニル、R21によって任意に置換された(C2〜C6)アルキニル、-C(O)OR9、-C(O)SR9、-C(O)NHR10、-C(O)N(R10)R9、-C(S)OR9、-C(S)SR9、-C(S)NHR10、-C(S)N(R10)R9、フェニル、(Z)p1によって置換されたフェニル、(Z)p1によって置換されたフェノキシフェニル、(Z)p1によって置換されたピリジルオキシフェニル、L-1〜L-4、L-8〜L-13、L-15〜L-23、L-25〜L-35、L-37、L-38、L-40、L-43〜L-58、M-4、M-5、M-8、M-9、M-14〜M-18又はM-19を表すか、或いは、隣接位に存在するYと一緒になってC2〜C3アルキレン鎖を形成することにより、ベンゼン環と縮合する５〜６員環を形成してもよいことを表し、このときこのアルキレン鎖は酸素原子、硫黄原子又は窒素原子を１個含んでもよく、且つハロゲン原子又はC1〜C6ハロアルキル基によって任意に置換されていてもよく、
R6は、水素原子、C1〜C6アルキル、C1〜C6ハロアルキル、C1〜C4アルコキシ(C1〜C4)アルキル、C1〜C4アルキルチオ(C1〜C4)アルキル、シアノ(C1〜C6)アルキル、フェニル(C1〜C4)アルキル、(Z)p1によって置換されたフェニル(C1〜C4)アルキル、C3〜C6アルケニル、C3〜C6ハロアルケニル、フェニル(C3〜C6)アルケニル、(Z)p1によって置換されたフェニル(C3〜C6)アルケニル、C3〜C6アルキニル、C3〜C6ハロアルキニル、フェニル(C3〜C6)アルキニル、(Z)p1によって置換されたフェニル(C3〜C6)アルキニル、-S(O)2R9、-C(O)R9、-C(O)NHR10、-C(O)N(R10)R9、-C(S)NHR10、-C(S)N(R10)R9、-Si(R13)(R14)R12、-P(O)(OR22)2又は-P(S)(OR22)2を表し、
Zは、ハロゲン原子、シアノ、ニトロ、C1〜C6アルキル、C1〜C6ハロアルキル、C1〜C3アルキルチオ(C1〜C3)アルキル、C1〜C3ハロアルキルチオ(C1〜C3)アルキル、C1〜C3アルキルスルフィニル(C1〜C3)アルキル、C1〜C3ハロアルキルスルフィニル(C1〜C3)アルキル、C1〜C3アルキルスルホニル(C1〜C3)アルキル、C1〜C3ハロアルキルスルホニル(C1〜C3)アルキル、C1〜C6アルコキシ、C1〜C6ハロアルコキシ、C1〜C3ハロアルコキシ(C1〜C3)ハロアルコキシ、C1〜C6アルキルスルホニルオキシ、C1〜C6ハロアルキルスルホニルオキシ、C1〜C6アルキルチオ、C1〜C6ハロアルキルチオ、C1〜C6アルキルスルフィニル、C1〜C6ハロアルキルスルフィニル、C1〜C6アルキルスルホニル、C1〜C6ハロアルキルスルホニル、-C(O)NH2又は-C(S)NH2を表し、p1, p2, p3又はp4が２以上の整数を表すとき、各々のZは互いに同一であっても又は互いに相異なっていてもよく、
さらに、２つのZが隣接する場合には、隣接する２つのZは-CF2CF2O-, -CF2OCF2-, -OCF2O-, -OCF2CHFO-, -OCF2CF2O-又は-CH=CHCH=CH-を形成することにより、２つのZのそれぞれが結合する炭素原子と共に５員環又は６員環を形成してもよく、
R9は、C1〜C6アルキル、C1〜C6ハロアルキル、C3〜C6シクロアルキル(C1〜C4)アルキル、フェニル(C1〜C4)アルキル、(Z)p1によって置換されたフェニル(C1〜C4)アルキル、C3〜C8シクロアルキル、C3〜C8ハロシクロアルキル、フェニル又は(Z)p1によって置換されたフェニルを表し、
R10は、水素原子又はC1〜C6アルキルを表すか、或いは、R9とR10とが一緒になってC4〜C5アルキレン鎖を形成することにより、結合する窒素原子と共に５員環又は６員環を形成してもよいことを表し、このときこのアルキレン鎖は酸素原子又は硫黄原子を１個含んでもよく、
R12は、C1〜C6アルキル、フェニル又は(Z)p1によって置換されたフェニルを表し、
R13及びR14は、各々独立してC1〜C6アルキルを表し、
R15は、C1〜C6アルキル、C1〜C6ハロアルキル、フェニル(C1〜C4)アルキル、(Z)p1によって置換されたフェニル(C1〜C4)アルキル、フェニル又は(Z)p1によって置換されたフェニルを表し、
R16は、ハロゲン原子、シアノ、C3〜C6シクロアルキル、-OR26、-N(R27)R26、-S(O)rR28、-SO2N(R30)R29、C1〜C6アルコキシカルボニル、-C(O)N(R30)R29、-C(R32)=NOH、-C(R32)=NOR31、-Si(R13)(R14)R12、フェニル、(Z)p1によって置換されたフェニル、L-1、L-2、L-3、L-4、L-45、L-46、L-47又はMを表し、
R17は、C1〜C6アルキル、C1〜C6アルコキシカルボニル(C1〜C4)アルキル又はC1〜C6アルコキシカルボニルを表し、
R18は、C1〜C6アルキルを表すか、或いは、R17とR18とが一緒になってC4〜C5アルキレン鎖を形成することにより、結合する窒素原子と共に５員環又は６員環を形成してもよいことを表し、このときこのアルキレン鎖は酸素原子又は硫黄原子１個を含んでもよく、且つメチル基又はメトキシ基によって任意に置換されていてもよく、
R21は、シアノ、C3〜C6シクロアルキル、C3〜C6ハロシクロアルキル、C1〜C6アルコキシ、C1〜C6ハロアルコキシ、フェノキシ、(Z)p1によって置換されたフェノキシ、C1〜C6アルキルチオ、C1〜C6ハロアルキルチオ、フェニルチオ、(Z)p1によって置換されたフェニルチオ、C1〜C6アルキルスルフィニル、C1〜C6ハロアルキルスルフィニル、C1〜C6アルキルスルホニル、C1〜C6ハロアルキルスルホニル、フェニルスルホニル、(Z)p1によって置換されたフェニルスルホニル、C1〜C6アルキルアミノ、ジ(C1〜C6アルキル)アミノ、フェニルアミノ、(Z)p1によって置換されたフェニルアミノ、C1〜C6アルコキシカルボニル、フェニル、(Z)p1によって置換されたフェニル、L-1〜L-5、L-8〜L-24、L-36、L-39、L-45〜L-52又はL-53を表し、
R22は、C1〜C6アルキルを表し、
R23は、C1〜C4アルキルを表し、q1, q2, q3又はq4が２以上の整数を表すとき、各々のR23は互いに同一であっても、または互いに相異なっていてもよく、
R24は、-CHO、C1〜C6アルキルカルボニル、C1〜C6アルコキシカルボニル又はC1〜C6アルキルスルホニルを表し、
R26は、水素原子、C1〜C6アルキル、C1〜C6ハロアルキル、C1〜C4アルコキシ(C1〜C4)アルキル、C1〜C4アルキルチオ(C1〜C4)アルキル、フェニル(C1〜C4)アルキル、(Z)p1によって置換されたフェニル(C1〜C4)アルキル、C1〜C6アルキルカルボニル、C1〜C6ハロアルキルカルボニル、C3〜C6シクロアルキルカルボニル、C1〜C6アルコキシカルボニル、-C(O)N(R30)R29、C1〜C6アルキルスルホニル、ジ(C1〜C6アルキル)アミノスルホニル、フェニルスルホニル、(Z)p1によって置換されたフェニルスルホニル、ジ(C1〜C6アルキル)ホスホリル、ジ(C1〜C6アルキル)チオホスホリル、トリ(C1〜C4アルキル)シリル、フェニル又は(Z)p1によって置換されたフェニルを表し、
R27は、水素原子又はC1〜C6アルキルを表し、
R28は、C1〜C6アルキル、C1〜C6ハロアルキル、ヒドロキシ(C1〜C4)アルキル、C1〜C4アルコキシ(C1〜C4)アルキル、C1〜C4アルキルチオ(C1〜C4)アルキル、C1〜C4アルキルカルボニル(C1〜C4)アルキル、C1〜C4アルコキシカルボニル(C1〜C4)アルキル、C1〜C4アルキルアミノカルボニル(C1〜C4)アルキル、ジ(C1〜C4アルキル)アミノカルボニル(C1〜C4)アルキル、トリ(C1〜C4アルキル)シリル(C1〜C4)アルキル、フェニル(C1〜C4)アルキル、(Z)p1によって置換されたフェニル(C1〜C4)アルキル、C3〜C6アルケニル、C3〜C6アルキニル、C1〜C6アルキルチオ、フェニル、(Z)p1によって置換されたフェニル、L-21、L-35、L-45又はL-48を表し、
R29は、C1〜C6アルキル、C1〜C4アルコキシ(C1〜C4)アルキル、C1〜C4アルキルチオ(C1〜C4)アルキル、フェニル(C1〜C4)アルキル、(Z)p1によって置換されたフェニル(C1〜C4)アルキル、C3〜C6シクロアルキル、C3〜C6アルケニル、C2〜C6アルキニル、フェニル又は(Z)p1によって置換されたフェニルを表し、
R30は、水素原子又はC1〜C6アルキルを表すか、或いは、R29とR30とが一緒になってC2〜C5アルキレン鎖を形成することにより、結合する窒素原子と共に３〜６員環を形成してもよいことを表し、このときこのアルキレン鎖は酸素原子又は硫黄原子を１個含んでもよく、
R31は、C1〜C6アルキル、フェニル(C1〜C4)アルキル又は(Z)p1によって置換されたフェニル(C1〜C4)アルキルを表し、
R32は、水素原子又はC1〜C6アルキルを表し、
mは、０〜３の整数を表し、
nは、０〜３の整数を表し、
q2、q3及びq4は、各々独立して０〜２の整数を表す上記〔１〕記載の置換ベンズアニリド化合物又はその塩。 [2] W 1 and W 2 represent oxygen atoms,
X is a halogen atom, cyano, nitro, C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, C 1 -C 6 alkoxy, C 1 -C 6 haloalkoxy, C 1 -C 6 alkylsulfonyloxy, C 1 -C 6 haloalkylsulfonyloxy, C 1 -C 6 alkylthio, C 1 -C 6 haloalkylthio, C 1 -C 6 alkylsulfinyl, C 1 -C 6 haloalkylsulfinyl, C 1 -C 6 alkylsulfonyl or C 1 -C 6 represents haloalkylsulfonyl, and when m represents 2 or 3, each X may be the same as or different from each other;
Further, when two Xs are adjacent to each other, the two adjacent Xs form —OCH 2 O— or —OCH 2 CH 2 O— to form a 5-membered ring or 6-membered together with the carbon atom to which each is bonded. may form a ring, this time, the hydrogen atoms bonded to each carbon atom forming the ring is optionally substituted by halogen atom, C 1 -C 4 alkyl or C 1 -C 4 haloalkyl group Well,
Y is a halogen atom, C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, hydroxy (C 1 ~C 6) alkyl, C 1 -C 3 alkoxy (C 1 ~C 3) alkyl, C 1 -C 6 alkoxy, C 1 -C 6 represents haloalkoxy, C 1 -C 6 alkylthio, C 1 -C 6 haloalkylthio, a C 1 -C 6 alkylamino or di (C 1 -C 6 alkyl) amino, n is 2 or 3 may be the same as or different from each other,
R 1 is C 1 -C 8 alkyl, (C 1 -C 8 ) alkyl optionally substituted by R 16 , C 3 -C 8 cycloalkyl, C 3 -C 8 alkenyl, C 3 -C 8 alkynyl, C 1 -C 8 -alkoxy, a M-4, M-5, M-8, M-9, M-13~M-19, M-21 or M-22,
R 2 and R 3 are each independently a hydrogen atom, C 1 -C 6 alkyl, C 1 -C 4 alkoxy (C 1 -C 4 ) alkyl, C 1 -C 4 alkylthio (C 1 -C 4 ) alkyl. , C 1 -C 4 alkylsulfonyl (C 1 ~C 4) alkyl, C 3 -C 6 alkenyl, C 3 -C 6 alkynyl, C 1 -C 6 alkylthio, C 1 -C 6 haloalkylthio, phenylthio, (Z ) represents phenylthio substituted by p1 or —SN (R 18 ) R 17 , or R 2 together with R 1 forms a C 2 -C 6 alkylene chain, together with the nitrogen atom to which it is attached. Represents that a 3- to 7-membered ring may be formed, in which case this alkylene chain may contain one oxygen or sulfur atom,
R 4 is optionally substituted by C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, optionally substituted by R 21 (C 1 ~C 6) alkyl, R 21 (C 1 ~C 6) represents haloalkyl, C 3 -C 8 cycloalkyl, C 3 -C 8 halocycloalkyl, C 3 -C 6 haloalkenyl, C 3 -C 6 haloalkynyl, phenyl substituted by phenyl or (Z) p1,
R 5 is cyano, optionally substituted by R 21 (C 1 ~C 6) alkyl, optionally substituted by R 21 (C 1 ~C 6) haloalkyl, C 3 -C 8 cycloalkyl, C 3 -C 8 halocycloalkyl, optionally substituted by R 21 (C 2 ~C 6) alkenyl, optionally substituted by R 21 (C 2 ~C 6) alkynyl, -C (O) OR 9, - C (O) SR 9 , -C (O) NHR 10 , -C (O) N (R 10 ) R 9 , -C (S) OR 9 , -C (S) SR 9 , -C (S) NHR 10, -C (S) N ( R 10) R 9, phenyl, (Z) phenyl substituted by p1, (Z) phenoxyphenyl phenyl substituted by p1, pyridyloxy phenyl substituted by (Z) p1, L-1 ~ L-4, L-8 ~ L-13, L-15 ~ L-23, L-25 ~ L-35, L-37, L-38, L-40, L-43 ~ L- 58, M-4, M-5, M-8, M-9, M-14 to M-18 or M-19, or C 2 to C together with Y present in the adjacent position by forming a 3 alkylene chain, condensed with a benzene ring 5 Membered indicates that may form a ring, this time the alkylene chain an oxygen atom, may contain one sulfur atom or a nitrogen atom, optionally substituted and the halogen atom or a C 1 -C 6 haloalkyl group You can,
R 6 is a hydrogen atom, C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, C 1 -C 4 alkoxy (C 1 -C 4 ) alkyl, C 1 -C 4 alkylthio (C 1 -C 4 ) alkyl , cyano (C 1 ~C 6) alkyl, phenyl (C 1 ~C 4) alkyl, phenyl (C 1 ~C 4) substituted by (Z) p1 alkyl, C 3 -C 6 alkenyl, C 3 -C 6 haloalkenyl, phenyl (C 3 -C 6) alkenyl, (Z) phenyl substituted by p1 (C 3 -C 6) alkenyl, C 3 -C 6 alkynyl, C 3 -C 6 haloalkynyl, phenyl (C 3 -C 6 ) alkynyl, phenyl (C 3 -C 6 ) alkynyl substituted by (Z) p1 , -S (O) 2 R 9 , -C (O) R 9 , -C (O) NHR 10 , -C (O) N (R 10 ) R 9 , -C (S) NHR 10 , -C (S) N (R 10 ) R 9 , -Si (R 13 ) (R 14 ) R 12 , -P ( O) (OR 22 ) 2 or -P (S) (OR 22 ) 2
Z is a halogen atom, cyano, nitro, C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, C 1 -C 3 alkylthio (C 1 ~C 3) alkyl, C 1 -C 3 haloalkylthio (C 1 ~ C 3) alkyl, C 1 -C 3 alkylsulfinyl (C 1 ~C 3) alkyl, C 1 -C 3 haloalkylsulfinyl (C 1 ~C 3) alkyl, C 1 -C 3 alkylsulfonyl (C 1 -C 3 ) alkyl, C 1 -C 3 haloalkylsulfonyl (C 1 -C 3) alkyl, C 1 -C 6 alkoxy, C 1 -C 6 haloalkoxy, C 1 -C 3 haloalkoxy (C 1 -C 3) haloalkoxy , C 1 -C 6 alkylsulfonyloxy, C 1 -C 6 haloalkylsulfonyloxy, C 1 -C 6 alkylthio, C 1 -C 6 haloalkylthio, C 1 -C 6 alkylsulfinyl, C 1 -C 6 haloalkylsulfinyl, C 1 -C 6 alkylsulfonyl, C 1 -C 6 haloalkylsulfonyl, -C (O) NH 2 or - Represents C (S) NH 2, and when p1, p2, p3 or p4 represents an integer of 2 or more, each Z may be the same as or different from each other;
Further, when two Zs are adjacent, the two adjacent Zs are -CF 2 CF 2 O-, -CF 2 OCF 2- , -OCF 2 O-, -OCF 2 CHFO-, -OCF 2 CF 2 By forming O- or -CH = CHCH = CH-, a 5-membered ring or a 6-membered ring may be formed together with the carbon atom to which each of two Zs is bonded,
R 9 is C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, C 3 -C 6 cycloalkyl (C 1 -C 4 ) alkyl, phenyl (C 1 -C 4 ) alkyl, (Z) substituted by p1 phenyl (C 1 ~C 4) represents alkyl, C 3 -C 8 cycloalkyl, C 3 -C 8 halocycloalkyl, phenyl substituted by phenyl or (Z) p1,
R 10 represents a hydrogen atom or C 1 -C 6 alkyl, or R 9 and R 10 together form a C 4 -C 5 alkylene chain to form a 5-membered atom together with the nitrogen atom to which it is attached. Represents that a ring or a 6-membered ring may be formed, in which case the alkylene chain may contain one oxygen atom or sulfur atom,
R 12 represents C 1 -C 6 alkyl, phenyl or phenyl substituted by (Z) p 1
R 13 and R 14 each independently represent C 1 -C 6 alkyl;
R 15 is, C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, phenyl (C 1 ~C 4) alkyl, phenyl (C 1 ~C 4) substituted by (Z) p1 alkyl, phenyl or (Z ) represents phenyl substituted by p1 ,
R 16 is a halogen atom, cyano, C 3 -C 6 cycloalkyl, -OR 26 , -N (R 27 ) R 26 , -S (O) r R 28 , -SO 2 N (R 30 ) R 29 , C 1 -C 6 alkoxycarbonyl, -C (O) N (R 30) R 29, -C (R 32) = NOH, -C (R 32) = NOR 31, -Si (R 13) (R 14) R 12 represents phenyl, phenyl substituted by (Z) p1 , L-1, L-2, L-3, L-4, L-45, L-46, L-47 or M;
R 17 represents C 1 -C 6 alkyl, C 1 -C 6 alkoxycarbonyl (C 1 -C 4 ) alkyl or C 1 -C 6 alkoxycarbonyl,
R 18 represents C 1 -C 6 alkyl, or R 17 and R 18 together form a C 4 -C 5 alkylene chain to form a 5-membered ring or 6 together with the nitrogen atom to which R 18 is bonded. The alkylene chain may contain one oxygen atom or one sulfur atom, and may be optionally substituted with a methyl group or a methoxy group,
R 21 is cyano, C 3 -C 6 cycloalkyl, C 3 -C 6 halocycloalkyl, C 1 -C 6 alkoxy, C 1 -C 6 haloalkoxy, phenoxy, (Z) phenoxy substituted by p 1 , C 1 -C 6 alkylthio, C 1 -C 6 haloalkylthio, phenylthio, (Z) phenylthio substituted by p1, C 1 -C 6 alkylsulfinyl, C 1 -C 6 haloalkylsulfinyl, C 1 -C 6 alkylsulfonyl , C 1 -C 6 haloalkylsulfonyl, phenylsulfonyl, phenylsulfonyl substituted by (Z) p1, C 1 ~C 6 alkyl amino, di (C 1 -C 6 alkyl) amino, phenylamino, by (Z) p1 substituted phenylamino, C 1 -C 6 alkoxycarbonyl, phenyl, (Z) phenyl substituted by p1, L-1~L-5, L-8~L-24, L-36, L-39, Represents L-45 to L-52 or L-53,
R 22 represents C 1 -C 6 alkyl;
R 23 represents C 1 -C 4 alkyl, and when q1, q2, q3 or q4 represents an integer of 2 or more, each R 23 may be the same as or different from each other;
R 24 represents -CHO, C 1 -C 6 alkylcarbonyl, a C 1 -C 6 alkoxycarbonyl or C 1 -C 6 alkylsulfonyl,
R 26 is a hydrogen atom, C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, C 1 -C 4 alkoxy (C 1 -C 4 ) alkyl, C 1 -C 4 alkylthio (C 1 -C 4 ) alkyl , phenyl (C 1 ~C 4) alkyl, (Z) phenyl substituted by p1 (C 1 ~C 4) alkyl, C 1 -C 6 alkylcarbonyl, C 1 -C 6 haloalkylcarbonyl, C 3 -C 6 cycloalkylcarbonyl, C 1 -C 6 alkoxycarbonyl, -C (O) N (R 30) R 29, C 1 ~C 6 alkyl sulfonyl, di (C 1 -C 6 alkyl) aminosulfonyl, phenylsulfonyl, (Z ) phenylsulfonyl substituted by p1, di (C 1 -C 6 alkyl) phosphoryl, di (C 1 -C 6 alkyl) thiophosphoryl, tri (C 1 -C 4 alkyl) silyl, by phenyl or (Z) p1 Represents substituted phenyl,
R 27 represents a hydrogen atom or a C 1 -C 6 alkyl,
R 28 is C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, hydroxy (C 1 -C 4 ) alkyl, C 1 -C 4 alkoxy (C 1 -C 4 ) alkyl, C 1 -C 4 alkylthio ( C 1 -C 4) alkyl, C 1 -C 4 alkylcarbonyl (C 1 -C 4) alkyl, C 1 -C 4 alkoxycarbonyl (C 1 -C 4) alkyl, C 1 -C 4 alkylaminocarbonyl (C 1 -C 4) alkyl, di (C 1 -C 4 alkyl) aminocarbonyl (C 1 -C 4) alkyl, tri (C 1 -C 4 alkyl) silyl (C 1 -C 4) alkyl, phenyl (C 1 -C 4) alkyl, (Z) phenyl substituted by p1 (C 1 ~C 4) alkyl, C 3 -C 6 alkenyl, C 3 -C 6 alkynyl, C 1 -C 6 alkylthio, phenyl, (Z) represents phenyl, L-21, L-35, L-45 or L-48 substituted by p1 ,
R 29 is C 1 -C 6 alkyl, C 1 -C 4 alkoxy (C 1 -C 4 ) alkyl, C 1 -C 4 alkylthio (C 1 -C 4 ) alkyl, phenyl (C 1 -C 4 ) alkyl. It is replaced by (Z) phenyl substituted by p1 (C 1 ~C 4) alkyl, C 3 -C 6 cycloalkyl, C 3 -C 6 alkenyl, C 2 -C 6 alkynyl, phenyl or (Z) p1 Represents phenyl,
R 30 represents a hydrogen atom or C 1 to C 6 alkyl, or R 29 and R 30 together form a C 2 to C 5 alkylene chain to form a 3- Represents that a 6-membered ring may be formed, in which case the alkylene chain may contain one oxygen or sulfur atom,
R 31 is, C 1 -C 6 alkyl, phenyl (C 1 ~C 4) phenyl substituted by alkyl or (Z) p1 (C 1 ~C 4) alkyl,
R 32 represents a hydrogen atom or C 1 -C 6 alkyl,
m represents an integer of 0 to 3,
n represents an integer of 0 to 3,
q2, q3 and q4 each independently represents an integer of 0 to 2, and the substituted benzanilide compound or a salt thereof according to the above [1].

〔３〕 Xは、ハロゲン原子、ニトロ、C1〜C6アルキル、C1〜C6ハロアルキル、C1〜C6アルコキシ、C1〜C6ハロアルコキシ、C1〜C6アルキルスルホニルオキシ、C1〜C6アルキルチオ、C1〜C6ハロアルキルチオ、C1〜C6アルキルスルフィニル、C1〜C6ハロアルキルスルフィニル、C1〜C6アルキルスルホニル又はC1〜C6ハロアルキルスルホニルを表し、mが２を表すとき、各々のXは互いに同一であっても又は互いに相異なっていてもよく、
Yは、ハロゲン原子、C1〜C6アルキル、C1〜C6ハロアルキル、C1〜C6アルコキシ又はC1〜C6アルキルチオを表し、nが２を表すとき、各々のYは互いに同一であっても又は互いに相異なっていてもよく、
R1は、C1〜C8アルキル、R16によって任意に置換された(C1〜C8)アルキル、C3〜C8アルケニル又はC3〜C8アルキニルを表し、
R2は、水素原子又はC1〜C6アルキルを表し、
R3は、水素原子を表し、
R4は、C1〜C6アルキル、C1〜C6ハロアルキル、C1〜C3アルコキシ(C1〜C3)ハロアルキル、C1〜C3アルキルチオ(C1〜C3)ハロアルキル、C3〜C6シクロアルキル又はC3〜C6ハロシクロアルキルを表し、
R5は、R21によって任意に置換された(C1〜C6)アルキル、R21によって任意に置換された(C1〜C6)ハロアルキル、R21によって任意に置換された(C2〜C6)アルケニル、R21によって任意に置換された(C2〜C6)アルキニル、C1〜C6アルコキシカルボニル、フェニル、(Z)p1によって置換されたフェニル、(Z)p1によって置換されたフェノキシフェニル、(Z)p1によって置換されたピリジルオキシフェニル、L-1〜L-4、L-8〜L-13、L-15〜L-23、L-45〜L-52又はL-53を表すか、或いは、隣接位に存在するYと一緒になってC2〜C3アルキレン鎖を形成することにより、ベンゼン環と縮合する５〜６員環を形成してもよいことを表し、このときこのアルキレン鎖は酸素原子、硫黄原子又は窒素原子を１個含んでもよく、且つハロゲン原子によって任意に置換されていてもよく、
R6は、水素原子、C1〜C6アルキル、C1〜C4アルコキシ(C1〜C4)アルキル、C1〜C6アルキルカルボニル又はトリ(C1〜C4アルキル)シリルを表し、
R16は、-OR26、-N(R27)R26、-S(O)rR28、-SO2N(R30)R29、-C(R32)=NOH又は-C(R32)=NOR31を表し、
R21は、C1〜C6アルコキシ、C1〜C6ハロアルコキシ、フェノキシ、(Z)p1によって置換されたフェノキシ、フェニルチオ、(Z)p1によって置換されたフェニルチオ、フェニルスルホニル、(Z)p1によって置換されたフェニルスルホニル、C1〜C6アルキルアミノ、ジ(C1〜C6アルキル)アミノ、フェニルアミノ、(Z)p1によって置換されたフェニルアミノ、C1〜C6アルコキシカルボニル、フェニル、(Z)p1によって置換されたフェニル、L-1〜L-5、L-8〜L-24、L-36、L-39、L-45〜L-52又はL-53を表し、
R26は、水素原子、C1〜C6アルキル、C1〜C6アルキルカルボニル、C1〜C6アルコキシカルボニル、C1〜C6アルキルアミノカルボニル、ジ(C1〜C6アルキル)アミノカルボニル又はC1〜C6アルキルスルホニルを表し、
R28は、C1〜C6アルキルを表し、
R29は、C1〜C6アルキルを表し、
R30は、水素原子又はC1〜C6アルキルを表し、
R31は、C1〜C6アルキルを表し、
R32は、水素原子を表し、
mは、０〜２の整数を表し、
nは、０〜２の整数を表す上記〔２〕記載の置換ベンズアニリド化合物又はその塩。 [3] X is a halogen atom, nitro, C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, C 1 -C 6 alkoxy, C 1 -C 6 haloalkoxy, C 1 -C 6 alkylsulfonyloxy, C 1 -C 6 alkylthio, represent C 1 -C 6 haloalkylthio, C 1 -C 6 alkylsulfinyl, C 1 -C 6 haloalkylsulfinyl, C 1 -C 6 alkylsulfonyl or C 1 -C 6 haloalkylsulfonyl, m is 2 represents each X may be the same as or different from each other;
Y is a halogen atom, C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, C 1 -C 6 alkoxy or C 1 -C 6 alkylthio, when n is 2, each Y is identical to each other May be different from each other,
R 1 represents C 1 -C 8 alkyl, (C 1 -C 8 ) alkyl, C 3 -C 8 alkenyl or C 3 -C 8 alkynyl optionally substituted by R 16 ,
R 2 represents a hydrogen atom or C 1 -C 6 alkyl,
R 3 represents a hydrogen atom,
R 4 is C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, C 1 -C 3 alkoxy (C 1 -C 3 ) haloalkyl, C 1 -C 3 alkylthio (C 1 -C 3 ) haloalkyl, C 3 -C 6 cycloalkyl or C 3 -C 6 halocycloalkyl,
R 5 is optionally substituted by R 21 (C 1 ~C 6) alkyl, optionally substituted by R 21 (C 1 ~C 6) haloalkyl, optionally substituted by R 21 (C 2 ~ C 6) alkenyl, optionally substituted by R 21 (C 2 ~C 6) alkynyl, C 1 -C 6 alkoxycarbonyl, phenyl, phenyl substituted by (Z) p1, substituted by (Z) p1 Phenoxyphenyl, pyridyloxyphenyl substituted by (Z) p1 , L-1 to L-4, L-8 to L-13, L-15 to L-23, L-45 to L-52 or L-53 or it represents, or indicates that by forming a C 2 -C 3 alkylene chain together with Y being present on the adjacent positions, may form a 5- or 6-membered ring fused with a benzene ring, In this case, the alkylene chain may contain one oxygen atom, sulfur atom or nitrogen atom, and may be optionally substituted with a halogen atom. ,
R 6 represents a hydrogen atom, C 1 -C 6 alkyl, C 1 -C 4 alkoxy (C 1 -C 4 ) alkyl, C 1 -C 6 alkylcarbonyl or tri (C 1 -C 4 alkyl) silyl;
R 16 is -OR 26 , -N (R 27 ) R 26 , -S (O) r R 28 , -SO 2 N (R 30 ) R 29 , -C (R 32 ) = NOH or -C (R 32 ) = NOR 31
R 21 is, C 1 -C 6 alkoxy, C 1 -C 6 haloalkoxy, phenoxy, (Z) p1 phenoxy substituted by, phenylthio, phenylthio substituted by (Z) p1, phenylsulfonyl, (Z) p1 phenylsulfonyl substituted by, C 1 -C 6 alkylamino, di (C 1 -C 6 alkyl) amino, phenylamino, (Z) phenylamino substituted by p1, C 1 -C 6 alkoxycarbonyl, phenyl, (Z) represents phenyl substituted by p1 , L-1 to L-5, L-8 to L-24, L-36, L-39, L-45 to L-52 or L-53;
R 26 is a hydrogen atom, C 1 -C 6 alkyl, C 1 -C 6 alkylcarbonyl, C 1 -C 6 alkoxycarbonyl, C 1 -C 6 alkylaminocarbonyl, di (C 1 -C 6 alkyl) aminocarbonyl or represents C 1 -C 6 alkylsulfonyl,
R 28 represents C 1 -C 6 alkyl,
R 29 represents C 1 -C 6 alkyl;
R 30 represents a hydrogen atom or C 1 -C 6 alkyl,
R 31 represents C 1 -C 6 alkyl;
R 32 represents a hydrogen atom,
m represents an integer of 0 to 2,
n is a substituted benzanilide compound or a salt thereof according to the above [2], wherein n represents an integer of 0 to 2.

〔４〕 Xは、ハロゲン原子、ニトロ、C1〜C4アルキル、C1〜C4ハロアルキル、C1〜C4アルキルチオ、C1〜C4アルキルスルフィニル又はC1〜C4アルキルスルホニルを表し、mが２を表すとき、各々のXは互いに同一であっても又は互いに相異なっていてもよく、
Yは、ハロゲン原子又はC1〜C4アルキルを表し、nが２を表すとき、各々のYは互いに同一であっても又は互いに相異なっていてもよく、
R1は、C1〜C8アルキル、C1〜C4アルキルチオ(C1〜C4)アルキル、C1〜C4アルキルスルフィニル(C1〜C4)アルキル又はC1〜C4アルキルスルホニル(C1〜C4)アルキルを表し、
R2は、水素原子を表し、
R4は、C1〜C6アルキル又はC1〜C6ハロアルキルを表し、
R5は、フェニル、(Z)p1によって置換されたフェニル、(Z)p1によって置換されたフェノキシフェニル、(Z)p1によって置換されたピリジルオキシフェニル、L-1〜L-4、L-8〜L-13、L-15〜L-23、L-45〜L-52又はL-53を表し、
R6は、水素原子を表す上記〔３〕記載の置換ベンズアニリド化合物又はその塩。 [4] X represents a halogen atom, nitro, C 1 -C 4 alkyl, C 1 -C 4 haloalkyl, C 1 -C 4 alkylthio, a C 1 -C 4 alkylsulfinyl or C 1 -C 4 alkylsulfonyl, when m represents 2, each X may be the same as or different from each other;
Y represents a halogen atom or a C 1 -C 4 alkyl, when n is 2, each Y may be the even or different from each other the same as each other,
R 1 is C 1 -C 8 alkyl, C 1 -C 4 alkylthio (C 1 -C 4 ) alkyl, C 1 -C 4 alkylsulfinyl (C 1 -C 4 ) alkyl or C 1 -C 4 alkylsulfonyl ( C 1 -C 4) alkyl,
R 2 represents a hydrogen atom,
R 4 represents C 1 -C 6 alkyl or C 1 -C 6 haloalkyl,
R 5 is phenyl, (Z) phenyl substituted by p1, (Z) phenoxyphenyl phenyl substituted by p1, (Z) pyridyloxy phenyl substituted by p1, L-1~L-4, L-8 ~ L-13, L-15 ~ L-23, L-45 ~ L-52 or L-53,
R 6 represents a substituted benzanilide compound or a salt thereof according to the above [3], which represents a hydrogen atom.

〔５〕 一般式（２）又は一般式（３）：   [5] General formula (2) or general formula (3):

Figure 2005126418
Figure 2005126418

［式中、Y1は、水素原子、ハロゲン原子、C1〜C6アルキル、C1〜C6ハロアルキル、C1〜C6アルコキシ又はC1〜C6アルキルチオを表し、
Y2及びY3は、各々独立して水素原子を表すか、或いは、R5と一緒になってC2〜C3アルキレン鎖を形成することにより、ベンゼン環と縮合する５〜６員環を形成してもよいことを表し、このときこのアルキレン鎖は酸素原子、硫黄原子又は窒素原子を１個含んでもよく、且つハロゲン原子によって任意に置換されていてもよく、
R4は、C1〜C6アルキル、C1〜C6ハロアルキル、C1〜C3アルコキシ(C1〜C3)ハロアルキル、C1〜C3アルキルチオ(C1〜C3)ハロアルキル、C3〜C6シクロアルキル又はC3〜C6ハロシクロアルキルを表し、
R5は、R21によって任意に置換された(C1〜C6)アルキル、R21によって任意に置換された(C1〜C6)ハロアルキル、R21によって任意に置換された(C2〜C6)アルケニル、R21によって任意に置換された(C2〜C6)アルキニル、C1〜C6アルコキシカルボニル、フェニル、(Z)p1によって置換されたフェニル、(Z)p1によって置換されたフェノキシフェニル、(Z)p1によって置換されたピリジルオキシフェニル、L-1〜L-4、L-8〜L-13、L-15〜L-23、L-45〜L-52又はL-53を表し、
R6は、水素原子、C1〜C6アルキル、C1〜C4アルコキシ(C1〜C4)アルキル、C1〜C6アルキルカルボニル又はトリ(C1〜C4アルキル)シリルを表し、
R21は、C1〜C6アルコキシ、C1〜C6ハロアルコキシ、フェノキシ、(Z)p1によって置換されたフェノキシ、フェニルチオ、(Z)p1によって置換されたフェニルチオ、フェニルスルホニル、(Z)p1によって置換されたフェニルスルホニル、C1〜C6アルキルアミノ、ジ(C1〜C6アルキル)アミノ、フェニルアミノ、(Z)p1によって置換されたフェニルアミノ、C1〜C6アルコキシカルボニル、フェニル、(Z)p1によって置換されたフェニル、L-1〜L-5、L-8〜L-24、L-36、L-39、L-45〜L-52又はL-53を表し、
L-1〜L-5、L-8〜L-24、L-36、L-39、L-45〜L-52又はL-53は、それぞれ下記の芳香族複素環を表し、 [Wherein Y 1 represents a hydrogen atom, a halogen atom, C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, C 1 -C 6 alkoxy or C 1 -C 6 alkylthio,
Y 2 and Y 3 each independently represent a hydrogen atom, or, together with R 5 , form a C 2 -C 3 alkylene chain to form a 5- to 6-membered ring condensed with a benzene ring. The alkylene chain may contain one oxygen atom, sulfur atom or nitrogen atom, and may be optionally substituted with a halogen atom,
R 4 is C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, C 1 -C 3 alkoxy (C 1 -C 3 ) haloalkyl, C 1 -C 3 alkylthio (C 1 -C 3 ) haloalkyl, C 3 -C 6 cycloalkyl or C 3 -C 6 halocycloalkyl,
R 5 is optionally substituted by R 21 (C 1 ~C 6) alkyl, optionally substituted by R 21 (C 1 ~C 6) haloalkyl, optionally substituted by R 21 (C 2 ~ C 6) alkenyl, optionally substituted by R 21 (C 2 ~C 6) alkynyl, C 1 -C 6 alkoxycarbonyl, phenyl, phenyl substituted by (Z) p1, substituted by (Z) p1 Phenoxyphenyl, pyridyloxyphenyl substituted by (Z) p1 , L-1 to L-4, L-8 to L-13, L-15 to L-23, L-45 to L-52 or L-53 Represents
R 6 represents a hydrogen atom, C 1 -C 6 alkyl, C 1 -C 4 alkoxy (C 1 -C 4 ) alkyl, C 1 -C 6 alkylcarbonyl or tri (C 1 -C 4 alkyl) silyl;
R 21 is, C 1 -C 6 alkoxy, C 1 -C 6 haloalkoxy, phenoxy, (Z) p1 phenoxy substituted by, phenylthio, phenylthio substituted by (Z) p1, phenylsulfonyl, (Z) p1 phenylsulfonyl substituted by, C 1 -C 6 alkylamino, di (C 1 -C 6 alkyl) amino, phenylamino, (Z) phenylamino substituted by p1, C 1 -C 6 alkoxycarbonyl, phenyl, (Z) represents phenyl substituted by p1 , L-1 to L-5, L-8 to L-24, L-36, L-39, L-45 to L-52 or L-53;
L-1 to L-5, L-8 to L-24, L-36, L-39, L-45 to L-52 or L-53 each represents the following aromatic heterocycle:

Figure 2005126418
Figure 2005126418

Figure 2005126418
Figure 2005126418

Zは、ハロゲン原子、シアノ、ニトロ、C1〜C6アルキル、C1〜C6ハロアルキル、C1〜C3アルキルチオ(C1〜C3)アルキル、C1〜C3ハロアルキルチオ(C1〜C3)アルキル、C1〜C3アルキルスルフィニル(C1〜C3)アルキル、C1〜C3ハロアルキルスルフィニル(C1〜C3)アルキル、C1〜C3アルキルスルホニル(C1〜C3)アルキル、C1〜C3ハロアルキルスルホニル(C1〜C3)アルキル、C1〜C6アルコキシ、C1〜C6ハロアルコキシ、C1〜C3ハロアルコキシ(C1〜C3)ハロアルコキシ、C1〜C6アルキルスルホニルオキシ、C1〜C6ハロアルキルスルホニルオキシ、C1〜C6アルキルチオ、C1〜C6ハロアルキルチオ、C1〜C6アルキルスルフィニル、C1〜C6ハロアルキルスルフィニル、C1〜C6アルキルスルホニル、C1〜C6ハロアルキルスルホニル、-C(O)NH2又は-C(S)NH2を表し、p1, p2, p3又はp4が２以上の整数を表すとき、各々のZは互いに同一であっても又は互いに相異なっていてもよく、
さらに、２つのZが隣接する場合には、隣接する２つのZは-CF2CF2O-, -CF2OCF2-, -OCF2O-, -OCF2CHFO-, -OCF2CF2O-又は-CH=CHCH=CH-を形成することにより、２つのZのそれぞれが結合する炭素原子と共に５員環又は６員環を形成してもよく、
R15は、C1〜C6アルキル、フェニル又は(Z)p1によって置換されたフェニルを表し、
p1は、１〜５の整数を表し、
p2は、０〜４の整数を表し、
p3は、０〜３の整数を表し、
p4は、０〜２の整数を表し、
p5は、０又は１の整数を表し、
rは、０〜２の整数を表し、
tは、０又は１の整数を表す。］
で表されるＮ−置換フェニル−３−ニトロフタルイミド若しくは置換アニリン又はそれらの塩。 Z is a halogen atom, cyano, nitro, C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, C 1 -C 3 alkylthio (C 1 ~C 3) alkyl, C 1 -C 3 haloalkylthio (C 1 ~ C 3) alkyl, C 1 -C 3 alkylsulfinyl (C 1 ~C 3) alkyl, C 1 -C 3 haloalkylsulfinyl (C 1 ~C 3) alkyl, C 1 -C 3 alkylsulfonyl (C 1 -C 3 ) alkyl, C 1 -C 3 haloalkylsulfonyl (C 1 -C 3) alkyl, C 1 -C 6 alkoxy, C 1 -C 6 haloalkoxy, C 1 -C 3 haloalkoxy (C 1 -C 3) haloalkoxy , C 1 -C 6 alkylsulfonyloxy, C 1 -C 6 haloalkylsulfonyloxy, C 1 -C 6 alkylthio, C 1 -C 6 haloalkylthio, C 1 -C 6 alkylsulfinyl, C 1 -C 6 haloalkylsulfinyl, C 1 -C 6 alkylsulfonyl, C 1 -C 6 haloalkylsulfonyl, -C (O) NH 2 or - Represents C (S) NH 2, and when p1, p2, p3 or p4 represents an integer of 2 or more, each Z may be the same as or different from each other;
Further, when two Zs are adjacent, the two adjacent Zs are -CF 2 CF 2 O-, -CF 2 OCF 2- , -OCF 2 O-, -OCF 2 CHFO-, -OCF 2 CF 2 By forming O- or -CH = CHCH = CH-, a 5-membered ring or a 6-membered ring may be formed together with the carbon atom to which each of two Zs is bonded,
R 15 represents C 1 -C 6 alkyl, phenyl or phenyl substituted by (Z) p1 ,
p1 represents an integer of 1 to 5,
p2 represents an integer of 0 to 4,
p3 represents an integer of 0 to 3,
p4 represents an integer of 0 to 2,
p5 represents an integer of 0 or 1,
r represents an integer of 0 to 2;
t represents an integer of 0 or 1. ]
N-substituted phenyl-3-nitrophthalimide or substituted aniline represented by the formula:

〔６〕 上記〔１〕〜〔４〕のいずれかに記載の置換ベンズアニリド化合物及びその塩から選ばれる１種又は２種以上を有効成分として含有することを特徴とする有害生物防除剤。   [6] A pest control agent comprising one or more selected from the substituted benzanilide compound according to any one of [1] to [4] above and a salt thereof as an active ingredient.

〔７〕 上記〔１〕〜〔４〕のいずれかに記載の置換ベンズアニリド化合物及びその塩から選ばれる１種又は２種以上を有効成分として含有することを特徴とする農薬。   [7] An agrochemical comprising one or more selected from the substituted benzanilide compound according to any one of [1] to [4] above and a salt thereof as an active ingredient.

〔８〕 上記〔１〕〜〔４〕のいずれかに記載の置換ベンズアニリド化合物及びその塩から選ばれる１種又は２種以上を有効成分として含有することを特徴とする殺虫剤又は殺ダニ剤。   [8] An insecticide or acaricide characterized by containing, as an active ingredient, one or more selected from the substituted benzanilide compound according to any one of [1] to [4] above and a salt thereof.

殺虫剤や殺菌剤の長年にわたる使用により、近年、病害虫が抵抗性を獲得し、従来の殺虫剤や殺菌剤による防除が困難になっている。また、殺虫剤の一部には毒性の高いもの、長く環境中に残留するものが存在し、これらによる生態系の攪乱が問題となっている。一方、本発明化合物は多くの農業害虫、ハダニ類に対して優れた殺虫・殺ダニ活性を有し、既存の殺虫剤に対して抵抗性を獲得した害虫に対しても十分な防除効果を発揮する。さらに、ホ乳類、魚類及び益虫に対してほとんど悪影響を及ぼさず、低残留性で環境に対する負荷も軽い。   With the long-term use of insecticides and fungicides, pests have recently gained resistance, making it difficult to control with conventional insecticides and fungicides. In addition, some insecticides are highly toxic and those that remain in the environment for a long time. On the other hand, the compound of the present invention has excellent insecticidal and acaricidal activity against many agricultural pests and spider mites, and also exhibits a sufficient control effect against pests that have acquired resistance to existing insecticides. To do. Furthermore, it has little adverse effect on mammals, fish and beneficial insects, has low persistence, and has a light environmental impact.

従って、本発明は有用な新規有害生物防除剤を提供することができる。   Therefore, the present invention can provide a useful novel pest control agent.

本発明に包含される化合物には、置換基の種類によってはE-体及びZ-体の幾何異性体が存在する場合があるが、本発明はこれらE-体、Z-体又はE-体及びZ-体を任意の割合で含む混合物を包含するものである。また、本発明に包含される化合物は、１個又は２個以上の不斉炭素原子の存在に起因する光学活性体が存在するが、本発明は全ての光学活性体又はラセミ体を包含する。さらに、一般式（１）で表される本発明化合物においては、R2或いはR3が水素原子であるときに、場合によっては次式で表される互変異性体の存在が考えられるが、本発明はそれらの構造をも包含するものである。 The compounds encompassed by the present invention may have geometrical isomers of E-form and Z-form depending on the type of substituent, but the present invention is not limited to these E-form, Z-form or E-form. And a mixture containing the Z-form in an arbitrary ratio. In addition, the compounds included in the present invention include optically active substances resulting from the presence of one or more asymmetric carbon atoms, but the present invention includes all optically active substances or racemates. Furthermore, in the compound of the present invention represented by the general formula (1), when R 2 or R 3 is a hydrogen atom, the presence of a tautomer represented by the following formula is considered in some cases. The present invention includes these structures.

Figure 2005126418
Figure 2005126418

本発明に包含される化合物のうちで、常法に従って酸付加塩にすることができるものは、例えば、フッ化水素酸、塩酸、臭化水素酸、沃化水素酸等のハロゲン化水素酸の塩、硝酸、硫酸、燐酸、塩素酸、過塩素酸等の無機酸の塩、メタンスルホン酸、エタンスルホン酸、トリフルオロメタンスルホン酸、ベンゼンスルホン酸、p-トルエンスルホン酸等のスルホン酸の塩、ギ酸、酢酸、プロピオン酸、トリフルオロ酢酸、フマール酸、酒石酸、蓚酸、マレイン酸、リンゴ酸、コハク酸、安息香酸、マンデル酸、アスコルビン酸、乳酸、グルコン酸、クエン酸等のカルボン酸の塩又はグルタミン酸、アスパラギン酸等のアミノ酸の塩とすることができる。   Among the compounds included in the present invention, those that can be converted into acid addition salts according to a conventional method include, for example, hydrohalic acids such as hydrofluoric acid, hydrochloric acid, hydrobromic acid, hydroiodic acid, and the like. Salt of inorganic acid such as salt, nitric acid, sulfuric acid, phosphoric acid, chloric acid, perchloric acid, salt of sulfonic acid such as methanesulfonic acid, ethanesulfonic acid, trifluoromethanesulfonic acid, benzenesulfonic acid, p-toluenesulfonic acid, Salts of carboxylic acids such as formic acid, acetic acid, propionic acid, trifluoroacetic acid, fumaric acid, tartaric acid, succinic acid, maleic acid, malic acid, succinic acid, benzoic acid, mandelic acid, ascorbic acid, lactic acid, gluconic acid, citric acid, etc. A salt of an amino acid such as glutamic acid or aspartic acid can be used.

或いは、本発明に包含される化合物のうちで、常法に従って金属塩にすることができるものは、例えば、リチウム、ナトリウム、カリウムといったアルカリ金属の塩、カルシウム、バリウム、マグネシウムといったアルカリ土類金属の塩又はアルミニウムの塩とすることができる。   Alternatively, among the compounds included in the present invention, those that can be converted into a metal salt according to a conventional method include, for example, alkali metal salts such as lithium, sodium, and potassium, and alkaline earth metals such as calcium, barium, and magnesium. It can be a salt or a salt of aluminum.

次に、本明細書において示した各置換基の具体例を以下に示す。ここで、n-はノルマル、i-はイソ、s-はセカンダリー及びt-はターシャリーを各々意味し、Phはフェニルを意味する。   Next, specific examples of each substituent shown in the present specification are shown below. Here, n- represents normal, i- represents iso, s- represents secondary, and t- represents tertiary, and Ph represents phenyl.

本発明化合物におけるハロゲン原子としては、フッ素原子、塩素原子、臭素原子及びヨウ素原子が挙げられる。尚、本明細書中「ハロ」の表記もこれらのハロゲン原子を表す。   As a halogen atom in this invention compound, a fluorine atom, a chlorine atom, a bromine atom, and an iodine atom are mentioned. In the present specification, the notation “halo” also represents these halogen atoms.

本明細書におけるCa〜Cbアルキルの表記は、炭素原子数がa〜b個よりなる直鎖状又は分岐鎖状の炭化水素基を表し、例えばメチル基、エチル基、n-プロピル基、i-プロピル基、n-ブチル基、s-ブチル基、i-ブチル基、t-ブチル基、n-ペンチル基、1-メチルブチル基、2-メチルブチル基、3-メチルブチル基、1-エチルプロピル基、1,1-ジメチルプロピル基、1,2-ジメチルプロピル基、ネオペンチル基、n-ヘキシル基、1-メチルペンチル基、2-メチルペンチル基、3-メチルペンチル基、4-メチルペンチル基、1-エチルブチル基、2-エチルブチル基、1,1-ジメチルブチル基、1,2-ジメチルブチル基、1,3-ジメチルブチル基、2,2-ジメチルブチル基、2,3-ジメチルブチル基、3,3-ジメチルブチル基、1,1,2-トリメチルプロピル基、1,2,2-トリメチルプロピル基、1-エチル-1-メチルプロピル基、1-エチル-2-メチルプロピル基、ヘプチル基、1-メチルヘキシル基、1,1-ジメチルペンチル基、オクチル基、1-メチルヘプチル基、1,1-ジメチルヘキシル基、ノニル基、1-メチルオクチル基、1,1-ジメチルヘプチル基、デシル基、1-メチルノニル基、ウンデシル基、1-メチルデシル基、ドデシル基、1-メチルウンデシル基等が具体例として挙げられ、各々の指定の炭素原子数の範囲で選択される。 The notation of C a to C b alkyl in the present specification represents a linear or branched hydrocarbon group having a carbon number of a to b , for example, methyl group, ethyl group, n-propyl group, i-propyl group, n-butyl group, s-butyl group, i-butyl group, t-butyl group, n-pentyl group, 1-methylbutyl group, 2-methylbutyl group, 3-methylbutyl group, 1-ethylpropyl group 1,1-dimethylpropyl group, 1,2-dimethylpropyl group, neopentyl group, n-hexyl group, 1-methylpentyl group, 2-methylpentyl group, 3-methylpentyl group, 4-methylpentyl group, 1 -Ethylbutyl group, 2-ethylbutyl group, 1,1-dimethylbutyl group, 1,2-dimethylbutyl group, 1,3-dimethylbutyl group, 2,2-dimethylbutyl group, 2,3-dimethylbutyl group, 3 1,3-dimethylbutyl group, 1,1,2-trimethylpropyl group, 1,2,2-trimethylpropyl group, 1-ethyl-1-methylpropyl group Propyl group, 1-ethyl-2-methylpropyl group, heptyl group, 1-methylhexyl group, 1,1-dimethylpentyl group, octyl group, 1-methylheptyl group, 1,1-dimethylhexyl group, nonyl group, Specific examples include 1-methyloctyl group, 1,1-dimethylheptyl group, decyl group, 1-methylnonyl group, undecyl group, 1-methyldecyl group, dodecyl group, 1-methylundecyl group, etc. In the range of the number of carbon atoms.

本明細書におけるCa〜Cbハロアルキルの表記は、炭素原子に結合した水素原子が、ハロゲン原子によって任意に置換された、炭素原子数がa〜b個よりなる直鎖状又は分岐鎖状の炭化水素基を表し、このとき、２個以上のハロゲン原子によって置換されている場合、それらのハロゲン原子は互いに同一でも、または互いに相異なっていてもよい。例えばフルオロメチル基、クロロメチル基、ブロモメチル基、ジフルオロメチル基、ジクロロメチル基、トリフルオロメチル基、クロロジフルオロメチル基、トリクロロメチル基、ブロモジフルオロメチル基、2-フルオロエチル基、1-クロロエチル基、2-クロロエチル基、1-ブロモエチル基、2-ブロモエチル基、2,2-ジフルオロエチル基、1,2-ジクロロエチル基、2,2-ジクロロエチル基、2-ブロモ-2-クロロエチル基、2,2,2-トリフルオロエチル基、2,2,2-トリクロロエチル基、1,1,2,2-テトラフルオロエチル基、2-クロロ-1,1,2-トリフルオロエチル基、2-ブロモ-1,1,2-トリフルオロエチル基、ペンタフルオロエチル基、2-クロロ-1,1,2,2-テトラフルオロエチル基、1-クロロ-1,2,2,2-テトラフルオロエチル基、2-ブロモ-1,1,2,2-テトラフルオロエチル基、2,2-ジクロロ-1,1,2-トリフルオロエチル基、2,2,2-トリクロロ-1,1-ジフルオロエチル基、1-クロロプロピル基、2-クロロプロピル基、3-クロロプロピル基、3-ブロモプロピル基、2-フルオロ-1-メチルエチル基、2-クロロ-1-メチルエチル基、2-ブロモ-1-メチルエチル基、2,2,3,3,3-ペンタフルオロプロピル基、1,1,2,3,3,3-ヘキサフルオロプロピル基、2,2,2-トリフルオロ-1-トリフルオロメチルエチル基、ヘプタフルオロプロピル基、1,2,2,2-テトラフルオロ-1-トリフルオロメチルエチル基、2-ブロモ-1,1,2,3,3,3-ヘキサフルオロプロピル基、4-クロロブチル基、2-クロロ-1,1-ジメチルエチル基、2-ブロモ-1,1-ジメチルエチル基、3,3,3-トリフルオロ-1-メチルプロピル基、ノナフルオロブチル基、5-クロロペンチル基、2,3-ジブロモ-1,1-ジメチルプロピル基、6-クロロヘキシル基、トリデカフルオロヘキシル基、7-ブロモヘプチル基、8-クロロオクチル基、9-ブロモノニル基、10-クロロデシル基、11-ブロモウンデシル基、12-ブロモドデシル基等が具体例として挙げられ、各々の指定の炭素原子数の範囲で選択される。 In the present specification, C a -C b haloalkyl is represented by a linear or branched chain consisting of a to b carbon atoms in which a hydrogen atom bonded to a carbon atom is optionally substituted with a halogen atom. Represents a hydrocarbon group, and when substituted by two or more halogen atoms, the halogen atoms may be the same as or different from each other. For example, fluoromethyl group, chloromethyl group, bromomethyl group, difluoromethyl group, dichloromethyl group, trifluoromethyl group, chlorodifluoromethyl group, trichloromethyl group, bromodifluoromethyl group, 2-fluoroethyl group, 1-chloroethyl group, 2-chloroethyl group, 1-bromoethyl group, 2-bromoethyl group, 2,2-difluoroethyl group, 1,2-dichloroethyl group, 2,2-dichloroethyl group, 2-bromo-2-chloroethyl group, 2, 2,2-trifluoroethyl group, 2,2,2-trichloroethyl group, 1,1,2,2-tetrafluoroethyl group, 2-chloro-1,1,2-trifluoroethyl group, 2-bromo -1,1,2-trifluoroethyl group, pentafluoroethyl group, 2-chloro-1,1,2,2-tetrafluoroethyl group, 1-chloro-1,2,2,2-tetrafluoroethyl group 2-bromo-1,1,2,2-tetrafluoroethyl group, 2,2-dichloro-1,1,2-to Lifluoroethyl group, 2,2,2-trichloro-1,1-difluoroethyl group, 1-chloropropyl group, 2-chloropropyl group, 3-chloropropyl group, 3-bromopropyl group, 2-fluoro-1 -Methylethyl group, 2-chloro-1-methylethyl group, 2-bromo-1-methylethyl group, 2,2,3,3,3-pentafluoropropyl group, 1,1,2,3,3, 3-hexafluoropropyl group, 2,2,2-trifluoro-1-trifluoromethylethyl group, heptafluoropropyl group, 1,2,2,2-tetrafluoro-1-trifluoromethylethyl group, 2- Bromo-1,1,2,3,3,3-hexafluoropropyl group, 4-chlorobutyl group, 2-chloro-1,1-dimethylethyl group, 2-bromo-1,1-dimethylethyl group, 3, 3,3-trifluoro-1-methylpropyl group, nonafluorobutyl group, 5-chloropentyl group, 2,3-dibromo-1,1-dimethylpropyl group, 6-chlorohexyl group, tridecafluorohe Specific examples include syl group, 7-bromoheptyl group, 8-chlorooctyl group, 9-bromononyl group, 10-chlorodecyl group, 11-bromoundecyl group, 12-bromododecyl group, etc. It is selected in the range of the number of atoms.

本明細書におけるヒドロキシ(Ca〜Cb)アルキルの表記は、炭素原子に結合した水素原子が、水酸基によって任意に置換された、炭素原子数がa〜b個よりなる直鎖状又は分岐鎖状のアルキル基を表し、例えばヒドロキシメチル基、1-ヒドロキシエチル基、2-ヒドロキシエチル基、3-ヒドロキシプロピル基、2-ヒドロキシ-1-メチルエチル基、4-ヒドロキシブチル基、2-ヒドロキシ-1,1-ジメチルエチル基、3-ヒドロキシ-1-メチルプロピル基、6-ヒドロキシヘキシル基等が具体例として挙げられ、各々の指定の炭素原子数の範囲で選択される。 The notation of hydroxy (C a -C b ) alkyl in the present specification is a linear or branched chain consisting of a to b carbon atoms, wherein a hydrogen atom bonded to a carbon atom is optionally substituted with a hydroxyl group And represents, for example, a hydroxymethyl group, 1-hydroxyethyl group, 2-hydroxyethyl group, 3-hydroxypropyl group, 2-hydroxy-1-methylethyl group, 4-hydroxybutyl group, 2-hydroxy- Specific examples include a 1,1-dimethylethyl group, a 3-hydroxy-1-methylpropyl group, a 6-hydroxyhexyl group, and the like, and each is selected within the specified number of carbon atoms.

本明細書におけるシアノ(Ca〜Cb)アルキルの表記は、炭素原子に結合した水素原子が、シアノ基によって任意に置換された、炭素原子数がa〜b個よりなる直鎖状又は分岐鎖状のアルキル基を表し、例えばシアノメチル基、1-シアノエチル基、2-シアノエチル基、3-シアノプロピル基、1-シアノ-1-メチルエチル基、4-シアノブチル基、2-シアノ-1,1-ジメチルエチル基、1-シアノ-1-メチルプロピル基、6-シアノヘキシル基等が具体例として挙げられ、各々の指定の炭素原子数の範囲で選択される。 The notation of cyano (C a -C b ) alkyl in the present specification is linear or branched having a carbon number of a to b , wherein a hydrogen atom bonded to a carbon atom is optionally substituted with a cyano group Represents a chain alkyl group, for example, cyanomethyl group, 1-cyanoethyl group, 2-cyanoethyl group, 3-cyanopropyl group, 1-cyano-1-methylethyl group, 4-cyanobutyl group, 2-cyano-1,1 Specific examples include -dimethylethyl group, 1-cyano-1-methylpropyl group, 6-cyanohexyl group and the like, and each is selected within the range of the designated number of carbon atoms.

本明細書におけるCa〜Cbシクロアルキルの表記は、炭素原子数がa〜b個よりなる環状の炭化水素基を表し、３員環から６員環までの単環又は複合環構造を形成することが出来る。また、各々の環は指定の炭素原子数の範囲でアルキル基によって任意に置換されていてもよい。例えばシクロプロピル基、1-メチルシクロプロピル基、2-メチルシクロプロピル基、2,2-ジメチルシクロプロピル基、2,2,3,3-テトラメチルシクロプロピル基、シクロブチル基、シクロペンチル基、1-メチルシクロペンチル基、2-メチルシクロペンチル基、3-メチルシクロペンチル基、シクロヘキシル基、1-メチルシクロヘキシル基、2-メチルシクロヘキシル基、3-メチルシクロヘキシル基、4-メチルシクロヘキシル基、ビシクロ[2.2.1]ヘプタン-2-イル基等が具体例として挙げられ、各々の指定の炭素原子数の範囲で選択される。 In the present specification, C a -C b cycloalkyl represents a cyclic hydrocarbon group having a to b carbon atoms, and forms a monocyclic or complex ring structure having 3 to 6 members. I can do it. Each ring may be optionally substituted with an alkyl group within the range of the specified number of carbon atoms. For example, cyclopropyl group, 1-methylcyclopropyl group, 2-methylcyclopropyl group, 2,2-dimethylcyclopropyl group, 2,2,3,3-tetramethylcyclopropyl group, cyclobutyl group, cyclopentyl group, 1- Methylcyclopentyl group, 2-methylcyclopentyl group, 3-methylcyclopentyl group, cyclohexyl group, 1-methylcyclohexyl group, 2-methylcyclohexyl group, 3-methylcyclohexyl group, 4-methylcyclohexyl group, bicyclo [2.2.1] heptane Specific examples include -2-yl groups and the like, and each is selected within the range of the designated number of carbon atoms.

本明細書におけるCa〜Cbハロシクロアルキルの表記は、炭素原子に結合した水素原子が、ハロゲン原子によって任意に置換された、炭素原子数がa〜b個よりなる環状の炭化水素基を表し、３員環から６員環までの単環又は複合環構造を形成することが出来る。また、各々の環は指定の炭素原子数の範囲でアルキル基によって任意に置換されていてもよく、ハロゲン原子による置換は環構造部分であっても、側鎖部分であっても、或いはそれらの両方であってもよく、さらに、２個以上のハロゲン原子によって置換されている場合、それらのハロゲン原子は互いに同一でも、または互いに相異なっていてもよい。例えば1-ブロモシクロプロピル基、2,2-ジクロロシクロプロピル基、2,2-ジブロモシクロプロピル基、2,2-ジフルオロ-1-メチルシクロプロピル基、2,2-ジクロロ-1-メチルシクロプロピル基、2,2-ジブロモ-1-メチルシクロプロピル基、2,2-ジクロロ-3,3-ジメチルシクロプロピル基、2,2,3,3-テトラフルオロシクロブチル基、2-フルオロシクロヘキシル基、2-クロロシクロヘキシル基、3-クロロシクロヘキシル基、4-クロロシクロヘキシル基、2-トリフルオロメチルシクロヘキシル基、3-トリフルオロメチルシクロヘキシル基、4-トリフルオロメチルシクロヘキシル基等が具体例として挙げられ、各々の指定の炭素原子数の範囲で選択される。 In the present specification, C a -C b halocycloalkyl represents a cyclic hydrocarbon group having a to b carbon atoms in which a hydrogen atom bonded to a carbon atom is optionally substituted with a halogen atom. And can form monocyclic or complex ring structures from 3 to 6-membered rings. Each ring may be optionally substituted with an alkyl group within the range of the specified number of carbon atoms, and the substitution with a halogen atom may be a ring structure part, a side chain part, They may be both, and when substituted by two or more halogen atoms, the halogen atoms may be the same as or different from each other. For example, 1-bromocyclopropyl group, 2,2-dichlorocyclopropyl group, 2,2-dibromocyclopropyl group, 2,2-difluoro-1-methylcyclopropyl group, 2,2-dichloro-1-methylcyclopropyl Group, 2,2-dibromo-1-methylcyclopropyl group, 2,2-dichloro-3,3-dimethylcyclopropyl group, 2,2,3,3-tetrafluorocyclobutyl group, 2-fluorocyclohexyl group, Specific examples include 2-chlorocyclohexyl group, 3-chlorocyclohexyl group, 4-chlorocyclohexyl group, 2-trifluoromethylcyclohexyl group, 3-trifluoromethylcyclohexyl group, 4-trifluoromethylcyclohexyl group, etc. Is selected within the range of the specified number of carbon atoms.

本明細書におけるCa〜Cbアルケニルの表記は、炭素原子数がa〜b個よりなる直鎖状又は分岐鎖状で、且つ分子内に１個又は２個以上の二重結合を有する不飽和炭化水素基を表し、例えばビニル基、1-プロペニル基、1-メチルエテニル基、2-プロペニル基、1-ブテニル基、1-メチル-1-プロペニル基、2-メチル-1-プロペニル基、2-ブテニル基、1-メチル-2-プロペニル基、2-メチル-2-プロペニル基、3-ブテニル基、1,3-ブタジエニル基、1-メチル-2-ブテニル基、2-メチル-2-ブテニル基、3-メチル-2-ブテニル基、1,1-ジメチル-2-プロペニル基、2-ヘキセニル基、2-メチル-2-ペンテニル基、1,3-ジメチル-2-ブテニル基、1,1,2-トリメチル-2-プロペニル基、1,1-ジメチル-3-ブテニル基、2,4-ヘキサジエニル基、2-ヘプテニル基、1,1-ジメチル-4-ペンテニル基、2-オクテニル基、1-メチル-2-ヘプテニル基、2-ウンデセニル基、10-ウンデセニル基、2-ドデセニル基、11-ドデセニル基等が具体例として挙げられ、各々の指定の炭素原子数の範囲で選択される。 In the present specification, C a -C b alkenyl is a linear or branched chain composed of a to b carbon atoms and has one or more double bonds in the molecule. Represents a saturated hydrocarbon group, for example, vinyl group, 1-propenyl group, 1-methylethenyl group, 2-propenyl group, 1-butenyl group, 1-methyl-1-propenyl group, 2-methyl-1-propenyl group, 2 -Butenyl group, 1-methyl-2-propenyl group, 2-methyl-2-propenyl group, 3-butenyl group, 1,3-butadienyl group, 1-methyl-2-butenyl group, 2-methyl-2-butenyl group Group, 3-methyl-2-butenyl group, 1,1-dimethyl-2-propenyl group, 2-hexenyl group, 2-methyl-2-pentenyl group, 1,3-dimethyl-2-butenyl group, 1,1 , 2-trimethyl-2-propenyl group, 1,1-dimethyl-3-butenyl group, 2,4-hexadienyl group, 2-heptenyl group, 1,1-dimethyl-4-pentenyl group, 2-octenyl group, 1 - Chill-2-heptenyl group, 2-undecenyl group, 10-undecenyl group, 2-dodecenyl group, 11-dodecenyl group, etc. As a specific example, may be selected from the range of the specified number of carbon atoms.

本明細書におけるCa〜Cbハロアルケニルの表記は、炭素原子に結合した水素原子が、ハロゲン原子によって任意に置換された、炭素原子数がa〜b個よりなる直鎖状又は分岐鎖状で、且つ分子内に１個又は２個以上の二重結合を有する不飽和炭化水素基を表す。このとき、２個以上のハロゲン原子によって置換されている場合、それらのハロゲン原子は互いに同一でも、または互いに相異なっていてもよい。例えば2-クロロビニル基、2-ブロモビニル基、2,2-ジクロロビニル基、2,2-ジブロモビニル基、3-ブロモ-2-プロペニル基、1-クロロメチルビニル基、2-ブロモ-1-メチルビニル基、1-トリフルオロメチルビニル基、2-クロロ-3,3,3-トリフルオロ-1-プロペニル基、1-トリフルオロメチル-2,2-ジフルオロビニル基、2-クロロ-2-プロペニル基、3,3-ジフルオロ-2-プロペニル基、3,3-ジクロロ-2-プロペニル基、2,3,3-トリフルオロ-2-プロペニル基、2,3,3-トリクロロ-2-プロペニル基、4,4-ジフルオロ-3-ブテニル基、3,4,4-トリフルオロ-3-ブテニル基、3-クロロ-4,4,4-トリフルオロ-2-ブテニル基、3,3,3-トリフルオロ-1-メチル-1-プロペニル基、3,3,3-トリフルオロ-2-トリフルオロメチル-1-プロペニル基、1,3,3,3-テトラフルオロ-2-トリフルオロメチル-1-プロペニル基、3,3,4,4,5,5,5-ヘプタフルオロ-1-ペンテニル基、5,5-ジフルオロ-4-ペンテニル基、4,5,5-トリフルオロ-4-ペンテニル基、3,4,4,4-テトラフルオロ-3-トリフルオロメチル-1-ブテニル基、4,4,5,5,6,6,6-ヘプタフルオロ-2-ヘキセニル基、3,4,4,5,5,5-ヘキサフルオロ-3-トリフルオロメチル-1-ペンテニル基、2-パーフルオロヘキシルエテニル基等が具体例として挙げられ、各々の指定の炭素原子数の範囲で選択される。 In the present specification, C a -C b haloalkenyl is a linear or branched chain consisting of a to b carbon atoms in which a hydrogen atom bonded to a carbon atom is optionally substituted with a halogen atom. And an unsaturated hydrocarbon group having one or more double bonds in the molecule. At this time, when substituted with two or more halogen atoms, the halogen atoms may be the same as or different from each other. For example, 2-chlorovinyl group, 2-bromovinyl group, 2,2-dichlorovinyl group, 2,2-dibromovinyl group, 3-bromo-2-propenyl group, 1-chloromethylvinyl group, 2-bromo-1- Methyl vinyl group, 1-trifluoromethyl vinyl group, 2-chloro-3,3,3-trifluoro-1-propenyl group, 1-trifluoromethyl-2,2-difluorovinyl group, 2-chloro-2- Propenyl group, 3,3-difluoro-2-propenyl group, 3,3-dichloro-2-propenyl group, 2,3,3-trifluoro-2-propenyl group, 2,3,3-trichloro-2-propenyl group Group, 4,4-difluoro-3-butenyl group, 3,3,4-trifluoro-3-butenyl group, 3-chloro-4,4,4-trifluoro-2-butenyl group, 3,3,3 -Trifluoro-1-methyl-1-propenyl group, 3,3,3-trifluoro-2-trifluoromethyl-1-propenyl group, 1,3,3,3-tetrafluoro-2-trifluoromethyl- 1-propenyl group, 3,3,4,4,5,5,5-heptaf Oro-1-pentenyl group, 5,5-difluoro-4-pentenyl group, 4,5,5-trifluoro-4-pentenyl group, 3,4,4,4-tetrafluoro-3-trifluoromethyl-1 -Butenyl group, 4,4,5,5,6,6,6-heptafluoro-2-hexenyl group, 3,4,4,5,5,5-hexafluoro-3-trifluoromethyl-1-pentenyl Specific examples include a group, a 2-perfluorohexylethenyl group, and the like, and each is selected within the range of the designated number of carbon atoms.

本明細書におけるCa〜Cbシクロアルケニルの表記は、炭素原子数がa〜b個よりなる環状の、且つ１個又は２個以上の二重結合を有する不飽和炭化水素基を表し、３員環から６員環までの単環又は複合環構造を形成することが出来る。また、各々の環は指定の炭素原子数の範囲でアルキル基によって任意に置換されていてもよく、さらに、二重結合はendo-又はexo-のどちらの形式であってもよい。例えばシクロペンテン-1-イル基、2-シクロペンテン-1-イル基、3-シクロペンテン-1-イル基、シクロヘキセン-1-イル基、2-シクロヘキセン-1-イル基、3-シクロヘキセン-1-イル基、2-メチル-2-シクロヘキセン-1-イル基、3-メチル-2-シクロヘキセン-1-イル基、ビシクロ[2.2.1]-5-ヘプテン-2-イル基等が具体例として挙げられ、各々の指定の炭素原子数の範囲で選択される。 In the present specification, C a -C b cycloalkenyl represents a cyclic unsaturated hydrocarbon group having 1 to 2 carbon atoms and having 1 to 2 carbon atoms. A monocyclic or complex ring structure from a member ring to a 6-member ring can be formed. Each ring may be optionally substituted with an alkyl group within the range of the specified number of carbon atoms, and the double bond may be either endo- or exo-. For example, cyclopenten-1-yl group, 2-cyclopenten-1-yl group, 3-cyclopenten-1-yl group, cyclohexen-1-yl group, 2-cyclohexen-1-yl group, 3-cyclohexen-1-yl group Specific examples include 2-methyl-2-cyclohexen-1-yl group, 3-methyl-2-cyclohexen-1-yl group, bicyclo [2.2.1] -5-hepten-2-yl group, Each selected range of carbon atoms is selected.

本明細書におけるCa〜Cbハロシクロアルケニルの表記は、炭素原子に結合した水素原子が、ハロゲン原子によって任意に置換された、炭素原子数がa〜b個よりなる環状の、且つ１個又は２個以上の二重結合を有する不飽和炭化水素基を表し、３員環から６員環までの単環又は複合環構造を形成することが出来る。また、各々の環は指定の炭素原子数の範囲でアルキル基によって任意に置換されていてもよく、さらに、二重結合はendo-又はexo-のどちらの形式であってもよい。また、ハロゲン原子による置換は環構造部分であっても、側鎖部分であっても、或いはそれらの両方であってもよく、２個以上のハロゲン原子によって置換されている場合、それらのハロゲン原子は互いに同一でも、または互いに相異なっていても良い。例えば2-クロロビシクロ[2.2.1]-5-ヘプテン-2-イル基等が具体例として挙げられ、各々の指定の炭素原子数の範囲で選択される。 In the present specification, C a -C b halocycloalkenyl has the following meaning: a hydrogen atom bonded to a carbon atom is optionally substituted with a halogen atom, a cyclic one having 1 to b carbon atoms, and one Alternatively, it represents an unsaturated hydrocarbon group having two or more double bonds, and can form a monocyclic or complex ring structure having 3 to 6 members. Each ring may be optionally substituted with an alkyl group within the range of the specified number of carbon atoms, and the double bond may be either endo- or exo-. In addition, the substitution by a halogen atom may be a ring structure part, a side chain part or both of them, and when substituted by two or more halogen atoms, those halogen atoms May be the same as or different from each other. For example, a 2-chlorobicyclo [2.2.1] -5-hepten-2-yl group and the like are given as specific examples, and each group is selected within the range of the designated number of carbon atoms.

本明細書におけるCa〜Cbアルキニルの表記は、炭素原子数がa〜b個よりなる直鎖状又は分岐鎖状で、且つ分子内に１個又は２個以上の三重結合を有する不飽和炭化水素基を表し、例えばエチニル基、1-プロピニル基、2-プロピニル基、1-メチル-2-プロピニル基、2-ブチニル基、3-ブチニル基、2-ペンチニル基、1-メチル-2-ブチニル基、1-メチル-3-ブチニル基、1,1-ジメチル-2-プロピニル基、1-ヘキシニル基、3,3-ジメチル-1-ブチニル基、2-ヘキシニル基、1-メチル-2-ペンチニル基、1,1-ジメチル-2-ブチニル基、2-ヘプチニル基、1,1-ジメチル-2-ペンチニル基、2-オクチニル基、2-ノニニル基、2-デシニル基、2-ウンデシニル基等が具体例として挙げられ、各々の指定の炭素原子数の範囲で選択される。 In the present specification, C a -C b alkynyl is a linear or branched chain having a carbon number of a to b , and is unsaturated having one or more triple bonds in the molecule. Represents a hydrocarbon group, such as ethynyl, 1-propynyl, 2-propynyl, 1-methyl-2-propynyl, 2-butynyl, 3-butynyl, 2-pentynyl, 1-methyl-2- Butynyl group, 1-methyl-3-butynyl group, 1,1-dimethyl-2-propynyl group, 1-hexynyl group, 3,3-dimethyl-1-butynyl group, 2-hexynyl group, 1-methyl-2- Pentynyl group, 1,1-dimethyl-2-butynyl group, 2-heptynyl group, 1,1-dimethyl-2-pentynyl group, 2-octynyl group, 2-noninyl group, 2-decynyl group, 2-undecynyl group, etc. Are given as specific examples and are selected within the range of each designated number of carbon atoms.

本明細書におけるCa〜Cbハロアルキニルの表記は、炭素原子に結合した水素原子が、ハロゲン原子によって任意に置換された、炭素原子数がa〜b個よりなる直鎖状又は分岐鎖状で、且つ分子内に１個又は２個以上の三重結合を有する不飽和炭化水素基を表す。このとき、２個以上のハロゲン原子によって置換されている場合、それらのハロゲン原子は互いに同一でも、または互いに相異なっていても良い。例えば2-クロロエチニル基、2-ブロモエチニル基、2-ヨードエチニル基、3-クロロ-2-プロピニル基、3-ブロモ-2-プロピニル基、3-ヨード-2-プロピニル基、3,3,3-トリフルオロ-1-プロピニル基、3-クロロ-1-メチル-2-プロピニル基、3-ブロモ-1-メチル-2-プロピニル基、3-ヨード-1-メチル-2-プロピニル基、3-クロロ-1,1-ジメチル-2-プロピニル基、3-ブロモ-1,1-ジメチル-2-プロピニル基、3-ヨード-1,1-ジメチル-2-プロピニル基等が具体例として挙げられ、各々の指定の炭素原子数の範囲で選択される。 In the present specification, C a -C b haloalkynyl represents a linear or branched chain having a to b carbon atoms in which a hydrogen atom bonded to a carbon atom is optionally substituted with a halogen atom. And an unsaturated hydrocarbon group having one or more triple bonds in the molecule. At this time, when substituted by two or more halogen atoms, the halogen atoms may be the same as or different from each other. For example, 2-chloroethynyl group, 2-bromoethynyl group, 2-iodoethynyl group, 3-chloro-2-propynyl group, 3-bromo-2-propynyl group, 3-iodo-2-propynyl group, 3,3, 3-trifluoro-1-propynyl group, 3-chloro-1-methyl-2-propynyl group, 3-bromo-1-methyl-2-propynyl group, 3-iodo-1-methyl-2-propynyl group, 3 Specific examples include -chloro-1,1-dimethyl-2-propynyl group, 3-bromo-1,1-dimethyl-2-propynyl group, 3-iodo-1,1-dimethyl-2-propynyl group and the like. , Each selected range of carbon atoms.

本明細書におけるCa〜Cbアルコキシの表記は、炭素原子数がa〜b個よりなる前記の意味であるアルキル-O-基を表し、例えばメトキシ基、エトキシ基、n-プロピルオキシ基、i-プロピルオキシ基、n-ブチルオキシ基、s-ブチルオキシ基、i-ブチルオキシ基、t-ブチルオキシ基、n-ペンチルオキシ基、1-メチルブチルオキシ基、2-メチルブチルオキシ基、3-メチルブチルオキシ基、1-エチルプロピルオキシ基、1,1-ジメチルプロピルオキシ基、1,2-ジメチルプロピルオキシ基、ネオペンチルオキシ基、n-ヘキシルオキシ基、1,1-ジメチルブチルオキシ基等が具体例として挙げられ、各々の指定の炭素原子数の範囲で選択される。 The notation of C a -C b alkoxy in the present specification represents an alkyl-O— group having the above-mentioned meaning consisting of a to b carbon atoms, for example, methoxy group, ethoxy group, n-propyloxy group, i-propyloxy group, n-butyloxy group, s-butyloxy group, i-butyloxy group, t-butyloxy group, n-pentyloxy group, 1-methylbutyloxy group, 2-methylbutyloxy group, 3-methylbutyl Specific examples include oxy, 1-ethylpropyloxy, 1,1-dimethylpropyloxy, 1,2-dimethylpropyloxy, neopentyloxy, n-hexyloxy, 1,1-dimethylbutyloxy As an example, each selected range of carbon atoms is selected.

本明細書におけるCa〜Cbハロアルコキシの表記は、炭素原子数がa〜b個よりなる前記の意味であるハロアルキル-O-基を表し、例えばジフルオロメトキシ基、トリフルオロメトキシ基、クロロジフルオロメトキシ基、ブロモジフルオロメトキシ基、2-フルオロエトキシ基、2-クロロエトキシ基、2,2,2-トリフルオロエトキシ基、1,1,2,2,-テトラフルオロエトキシ基、2-クロロ-1,1,2-トリフルオロエトキシ基、2-ブロモ-1,1,2-トリフルオロエトキシ基、ペンタフルオロエトキシ基、2-ブロモ-1,1,2,2-テトラフルオロエトキシ基、2,2-ジクロロ-1,1,2-トリフルオロエトキシ基、2,2,2-トリクロロ-1,1-ジフルオロエトキシ基、2-クロロプロピルオキシ基、3-クロロプロピルオキシ基、ヘプタフルオロプロピルオキシ基、2,2,2-トリフルオロ-1-トリフルオロメチルエトキシ基、2,2,3,3-テトラフルオロプロピルオキシ基、1,1,2,3,3,3-ヘキサフルオロプロピルオキシ基、2-ブロモ-1,1,2,3,3,3-ヘキサフルオロプロピルオキシ基等が具体例として挙げられ、各々の指定の炭素原子数の範囲で選択される。 The notation of C a -C b haloalkoxy in the present specification represents a haloalkyl-O— group having the above-mentioned meaning consisting of a to b carbon atoms, for example, difluoromethoxy group, trifluoromethoxy group, chlorodifluoro Methoxy group, bromodifluoromethoxy group, 2-fluoroethoxy group, 2-chloroethoxy group, 2,2,2-trifluoroethoxy group, 1,1,2,2, -tetrafluoroethoxy group, 2-chloro-1 1,2-trifluoroethoxy group, 2-bromo-1,1,2-trifluoroethoxy group, pentafluoroethoxy group, 2-bromo-1,1,2,2-tetrafluoroethoxy group, 2,2 -Dichloro-1,1,2-trifluoroethoxy group, 2,2,2-trichloro-1,1-difluoroethoxy group, 2-chloropropyloxy group, 3-chloropropyloxy group, heptafluoropropyloxy group, 2,2,2-trifluoro-1-trifluoromethylethoxy group 2,2,3,3-tetrafluoropropyloxy group, 1,1,2,3,3,3-hexafluoropropyloxy group, 2-bromo-1,1,2,3,3,3-hexafluoro Specific examples include a propyloxy group and the like, and each is selected within the range of the designated number of carbon atoms.

本明細書におけるCa〜Cbアルケニルオキシの表記は、炭素原子数がa〜b個よりなる前記の意味であるアルケニル-O-基を表し、例えば2-プロペニルオキシ基、2-ブテニルオキシ基、2-メチル-2-プロペニルオキシ基、3-メチル-2-ブテニルオキシ基等が具体例として挙げられ、各々の指定の炭素原子数の範囲で選択される。 The notation of C a -C b alkenyloxy in the present specification represents an alkenyl-O— group having the above-mentioned meaning consisting of a to b carbon atoms, such as 2-propenyloxy group, 2-butenyloxy group, Specific examples include 2-methyl-2-propenyloxy group, 3-methyl-2-butenyloxy group and the like, and each is selected within the range of the designated number of carbon atoms.

本明細書におけるCa〜Cbハロアルケニルオキシの表記は、炭素原子数がa〜b個よりなる前記の意味であるハロアルケニル-O-基を表し、例えば2-クロロ-2-プロペニル基、3-クロロ-2-プロペニル基、3,3-ジフルオロ-2-プロペニル基、3,3-ジクロロ-2-プロペニル基、2,3,3-トリフルオロ-2-プロペニル基等が具体例として挙げられ、各々の指定の炭素原子数の範囲で選択される。 The notation of C a -C b haloalkenyloxy in the present specification represents a haloalkenyl-O— group having the above-mentioned meaning consisting of a to b carbon atoms, such as a 2-chloro-2-propenyl group, Specific examples include 3-chloro-2-propenyl group, 3,3-difluoro-2-propenyl group, 3,3-dichloro-2-propenyl group, 2,3,3-trifluoro-2-propenyl group and the like. Selected within the range of each specified number of carbon atoms.

本明細書におけるCa〜Cbアルキルチオの表記は、炭素原子数がa〜b個よりなる前記の意味であるアルキル-S-基を表し、例えばメチルチオ基、エチルチオ基、n-プロピルチオ基、i-プロピルチオ基、n-ブチルチオ基、s-ブチルチオ基、i-ブチルチオ基、t-ブチルチオ基、n-ペンチルチオ基、1-メチルブチルチオ基、2-メチルブチルチオ基、3-メチルブチルチオ基、1-エチルプロピルチオ基、1,1-ジメチルプロピルチオ基、1,2-ジメチルプロピルチオ基、ネオペンチルチオ基、n-ヘキシルチオ基等が具体例として挙げられ、各々の指定の炭素原子数の範囲で選択される。 The notation of C a -C b alkylthio in the present specification represents an alkyl-S-group having the above-mentioned meaning consisting of a to b carbon atoms, for example, methylthio group, ethylthio group, n-propylthio group, i -Propylthio group, n-butylthio group, s-butylthio group, i-butylthio group, t-butylthio group, n-pentylthio group, 1-methylbutylthio group, 2-methylbutylthio group, 3-methylbutylthio group, Specific examples include 1-ethylpropylthio group, 1,1-dimethylpropylthio group, 1,2-dimethylpropylthio group, neopentylthio group, n-hexylthio group, and the like. Selected by range.

本明細書におけるCa〜Cbハロアルキルチオの表記は、炭素原子数がa〜b個よりなる前記の意味であるハロアルキル-S-基を表し、例えばジフルオロメチルチオ基、トリフルオロメチルチオ基、ブロモジフルオロメチルチオ基、2,2,2-トリフルオロエチルチオ基、1,1,2,2-テトラフルオロエチルチオ基、1,1,2-トリフルオロ-2-クロロエチルチオ基、ペンタフルオロエチルチオ基、2-ブロモ-1,1,2,2-テトラフルオロエチルチオ基、ヘプタフルオロプロピルチオ基、1,2,2,2-テトラフルオロ-1-トリフルオロメチルエチルチオ基、ノナフルオロブチルチオ基等が具体例として挙げられ、各々の指定の炭素原子数の範囲で選択される。 The notation of C a -C b haloalkylthio in the present specification represents a haloalkyl-S-group having the above-mentioned meaning consisting of a to b carbon atoms, for example, difluoromethylthio group, trifluoromethylthio group, bromodifluoro Methylthio group, 2,2,2-trifluoroethylthio group, 1,1,2,2-tetrafluoroethylthio group, 1,1,2-trifluoro-2-chloroethylthio group, pentafluoroethylthio group 2-bromo-1,1,2,2-tetrafluoroethylthio group, heptafluoropropylthio group, 1,2,2,2-tetrafluoro-1-trifluoromethylethylthio group, nonafluorobutylthio group Etc. are given as specific examples, and each is selected within the range of the designated number of carbon atoms.

本明細書におけるCa〜Cbアルキルスルフィニルの表記は、炭素原子数がa〜b個よりなる前記の意味であるアルキル-S(O)-基を表し、例えばメチルスルフィニル基、エチルスルフィニル基、n-プロピルスルフィニル基、i-プロピルスルフィニル基、n-ブチルスルフィニル基、s-ブチルスルフィニル基、i-ブチルスルフィニル基、t-ブチルスルフィニル基等が具体例として挙げられ、各々の指定の炭素原子数の範囲で選択される。 In the present specification, the notation of C a -C b alkylsulfinyl represents an alkyl-S (O) — group having the above-mentioned meaning consisting of a to b carbon atoms, for example, methylsulfinyl group, ethylsulfinyl group, Specific examples include n-propylsulfinyl group, i-propylsulfinyl group, n-butylsulfinyl group, s-butylsulfinyl group, i-butylsulfinyl group, t-butylsulfinyl group and the like. The range is selected.

本明細書におけるCa〜Cbハロアルキルスルフィニルの表記は、炭素原子数がa〜b個よりなる前記の意味であるハロアルキル-S(O)-基を表し、例えばジフルオロメチルスルフィニル基、トリフルオロメチルスルフィニル基、ブロモジフルオロメチルスルフィニル基、2,2,2-トリフルオロエチルスルフィニル基、2-ブロモ-1,1,2,2-テトラフルオロエチルスルフィニル基、1,2,2,2-テトラフルオロ-1-トリフルオロメチルエチルスルフィニル基、ノナフルオロブチルスルフィニル基等が具体例として挙げられ、各々の指定の炭素原子数の範囲で選択される。 In the present specification, the expression C a -C b haloalkylsulfinyl represents a haloalkyl-S (O) -group having the above-mentioned meaning consisting of a to b carbon atoms, for example, difluoromethylsulfinyl group, trifluoromethyl Sulfinyl group, bromodifluoromethylsulfinyl group, 2,2,2-trifluoroethylsulfinyl group, 2-bromo-1,1,2,2-tetrafluoroethylsulfinyl group, 1,2,2,2-tetrafluoro- Specific examples include 1-trifluoromethylethylsulfinyl group, nonafluorobutylsulfinyl group and the like, and each is selected within the range of the designated number of carbon atoms.

本明細書におけるCa〜Cbアルキルスルホニルの表記は、炭素原子数がa〜b個よりなる前記の意味であるアルキル-SO2-基を表し、例えばメタンスルホニル基、エタンスルホニル基、n-プロピルスルホニル基、i-プロピルスルホニル基、n-ブチルスルホニル基、s-ブチルスルホニル基、i-ブチルスルホニル基、t-ブチルスルホニル基、n-ペンチルスルホニル基、n-ヘキシルスルホニル基等が具体例として挙げられ、各々の指定の炭素原子数の範囲で選択される。 The notation of C a -C b alkylsulfonyl in the present specification represents an alkyl-SO 2 — group having the above-mentioned meaning consisting of a to b carbon atoms, such as methanesulfonyl group, ethanesulfonyl group, n- Specific examples include propylsulfonyl group, i-propylsulfonyl group, n-butylsulfonyl group, s-butylsulfonyl group, i-butylsulfonyl group, t-butylsulfonyl group, n-pentylsulfonyl group, n-hexylsulfonyl group and the like. Each of which is selected for each specified number of carbon atoms.

本明細書におけるCa〜Cbハロアルキルスルホニルの表記は、炭素原子数がa〜b個よりなる前記の意味であるハロアルキル-SO2-基を表し、例えばジフルオロメタンスルホニル基、トリフルオロメタンスルホニル基、クロロジフルオロメタンスルホニル基、ブロモジフルオロメタンスルホニル基、2,2,2-トリフルオロエタンスルホニル基、1,1,2,2-テトラフルオロエタンスルホニル基、1,1,2-トリフルオロ-2-クロロエタンスルホニル基等が具体例として挙げられ、各々の指定の炭素原子数の範囲で選択される。 The notation of C a -C b haloalkylsulfonyl in the present specification represents a haloalkyl-SO 2 -group having the above-mentioned meaning consisting of a to b carbon atoms, such as a difluoromethanesulfonyl group, a trifluoromethanesulfonyl group, Chlorodifluoromethanesulfonyl group, bromodifluoromethanesulfonyl group, 2,2,2-trifluoroethanesulfonyl group, 1,1,2,2-tetrafluoroethanesulfonyl group, 1,1,2-trifluoro-2-chloroethane A sulfonyl group etc. are mentioned as a specific example, It selects in the range of each designated carbon atom number.

本明細書におけるCa〜Cbアルキルアミノの表記は、水素原子の一方が炭素原子数がa〜b個よりなる前記の意味であるアルキル基によって置換されたアミノ基を表し、例えばメチルアミノ基、エチルアミノ基、n-プロピルアミノ基、i-プロピルアミノ基、n-ブチルアミノ基、i-ブチルアミノ基、t-ブチルアミノ基等が具体例として挙げられ、各々の指定の炭素原子数の範囲で選択される。 The notation of C a -C b alkylamino in the present specification represents an amino group in which one of the hydrogen atoms is substituted with an alkyl group having the above meaning consisting of a to b carbon atoms, for example, a methylamino group , Ethylamino group, n-propylamino group, i-propylamino group, n-butylamino group, i-butylamino group, t-butylamino group and the like. Selected by range.

本明細書におけるジ(Ca〜Cbアルキル)アミノの表記は、水素原子が両方とも、それぞれ同一でも又は互いに相異なっていてもよい炭素原子数がa〜b個よりなる前記の意味であるアルキル基によって置換されたアミノ基を表し、例えばジメチルアミノ基、エチル(メチル)アミノ基、ジエチルアミノ基、n-プロピル(メチル)アミノ基、i-プロピル(メチル)アミノ基、ジ(n-プロピル)アミノ基、n-ブチル(メチル)アミノ基、i-ブチル(メチル)アミノ基、t-ブチル(メチル)アミノ基等が具体例として挙げられ、各々の指定の炭素原子数の範囲で選択される。 In the present specification, the notation of di (C a -C b alkyl) amino has the above-mentioned meaning that the number of carbon atoms, which may be the same or different from each other, is ab. Represents an amino group substituted by an alkyl group, for example, dimethylamino group, ethyl (methyl) amino group, diethylamino group, n-propyl (methyl) amino group, i-propyl (methyl) amino group, di (n-propyl) Specific examples include amino groups, n-butyl (methyl) amino groups, i-butyl (methyl) amino groups, t-butyl (methyl) amino groups, and the like, each selected within the range of the specified number of carbon atoms. .

本明細書におけるCa〜Cbアルキルカルボニルの表記は、炭素原子数がa〜b個よりなる前記の意味であるアルキル-C(O)-基を表し、例えばCH3C(O)-基、CH3CH2C(O)-基、CH3CH2CH2C(O)-基、(CH3)2CHC(O)-基、CH3(CH2)3C(O)-基、(CH3)2CHCH2C(O)-基、CH3CH2CH(CH3)C(O)-基、(CH3)3CC(O)-基、CH3(CH2)4C(O)-基、CH3(CH2)5C(O)-基等が具体例として挙げられ、各々の指定の炭素原子数の範囲で選択される。 In the present specification, the expression C a -C b alkylcarbonyl represents an alkyl-C (O) -group having the above-mentioned meaning consisting of a- b carbon atoms, for example, CH 3 C (O) -group. , CH 3 CH 2 C (O)-group, CH 3 CH 2 CH 2 C (O)-group, (CH 3 ) 2 CHC (O)-group, CH 3 (CH 2 ) 3 C (O)-group , (CH 3 ) 2 CHCH 2 C (O)-group, CH 3 CH 2 CH (CH 3 ) C (O)-group, (CH 3 ) 3 CC (O)-group, CH 3 (CH 2 ) 4 Specific examples include C (O) — group, CH 3 (CH 2 ) 5 C (O) — group, etc., and each is selected within the range of the designated number of carbon atoms.

本明細書におけるCa〜Cbハロアルキルカルボニルの表記は、炭素原子数がa〜b個よりなる前記の意味であるハロアルキル-C(O)-基を表し、例えばFCH2C(O)-基、ClCH2C(O)-基、F2CHC(O)-基、Cl2CHC(O)-基、CF3C(O)-基、ClCF2C(O)-基、BrCF2C(O)-基、CCl3C(O)-基、CF3CF2C(O)-基、ClCH2CH2CH2C(O)-基、CF3CF2CF2C(O)-基、ClCH2C(CH3)2C(O)-基等が具体例として挙げられ、各々の指定の炭素原子数の範囲で選択される。 The notation of C a -C b haloalkylcarbonyl in the present specification represents a haloalkyl-C (O) -group having the above-mentioned meaning consisting of a to b carbon atoms, for example, FCH 2 C (O) -group , ClCH 2 C (O)-group, F 2 CHC (O)-group, Cl 2 CHC (O)-group, CF 3 C (O)-group, ClCF 2 C (O)-group, BrCF 2 C ( O)-group, CCl 3 C (O)-group, CF 3 CF 2 C (O)-group, ClCH 2 CH 2 CH 2 C (O)-group, CF 3 CF 2 CF 2 C (O)-group , ClCH 2 C (CH 3 ) 2 C (O) — groups and the like are listed as specific examples, and each is selected within the range of the designated number of carbon atoms.

本明細書におけるCa〜Cbシクロアルキルカルボニルの表記は、炭素原子数がa〜b個よりなる前記の意味であるシクロアルキル-C(O)-基を表し、例えばシクロプロピル-C(O)-基、1-メチルシクロプロピル-C(O)-基、2-メチルシクロプロピル-C(O)-基、2,2-ジメチルシクロプロピル-C(O)-基、シクロブチル-C(O)-基、シクロペンチル-C(O)-基、シクロヘキシル-C(O)-基等が具体例として挙げられ、各々の指定の炭素原子数の範囲で選択される。 In the present specification, the expression C a -C b cycloalkylcarbonyl represents a cycloalkyl-C (O) — group having the above-mentioned meaning consisting of a to b carbon atoms, for example, cyclopropyl-C (O )-Group, 1-methylcyclopropyl-C (O)-group, 2-methylcyclopropyl-C (O)-group, 2,2-dimethylcyclopropyl-C (O)-group, cyclobutyl-C (O ) -Groups, cyclopentyl-C (O) -groups, cyclohexyl-C (O) -groups, etc., are given as specific examples, each selected within the range of the number of carbon atoms specified.

本明細書におけるCa〜Cbアルコキシカルボニルの表記は、炭素原子数がa〜b個よりなる前記の意味であるアルキル-O-C(O)-基を表し、例えばCH3OC(O)-基、CH3CH2OC(O)-基、 CH3CH2CH2OC(O)-基、(CH3)2CHOC(O)-基、CH3(CH2)3OC(O)-基、(CH3)2CHCH2OC(O)-基、(CH3)3COC(O)-基等が具体例として挙げられ、各々の指定の炭素原子数の範囲で選択される。 The notation of C a -C b alkoxycarbonyl in the present specification represents an alkyl-OC (O) -group having the above-mentioned meaning consisting of a to b carbon atoms, for example, CH 3 OC (O) -group , CH 3 CH 2 OC (O)-group, CH 3 CH 2 CH 2 OC (O)-group, (CH 3 ) 2 CHOC (O)-group, CH 3 (CH 2 ) 3 OC (O)-group , (CH 3 ) 2 CHCH 2 OC (O) — group, (CH 3 ) 3 COC (O) — group, and the like are given as specific examples, and each is selected within the range of the designated number of carbon atoms.

本明細書におけるCa〜Cbハロアルコキシカルボニルの表記は、炭素原子数がa〜b個よりなる前記の意味であるハロアルキル-O-C(O)-基を表し、例えばClCH2CH2OC(O)-基、CF3CH2OC(O)-基等が具体例として挙げられ、各々の指定の炭素原子数の範囲で選択される。 In the present specification, the expression C a -C b haloalkoxycarbonyl represents a haloalkyl-OC (O) — group having the above-mentioned meaning consisting of a to b carbon atoms, such as ClCH 2 CH 2 OC (O ) -Groups, CF 3 CH 2 OC (O) -groups and the like are listed as specific examples, each selected within the range of the number of carbon atoms specified.

本明細書におけるCa〜Cbアルキルチオカルボニルの表記は、炭素原子数がa〜b個よりなる前記の意味であるアルキル-S-C(O)-基を表し、例えばCH3SC(O)-基、CH3CH2SC(O)-基、 CH3CH2CH2SC(O)-基、(CH3)2CHSC(O)-基、CH3(CH2)3SC(O)-基、(CH3)2CHCH2SC(O)-基、(CH3)3CSC(O)-基等が具体例として挙げられ、各々の指定の炭素原子数の範囲で選択される。 In the present specification, the expression C a -C b alkylthiocarbonyl represents an alkyl-SC (O) -group having the above-mentioned meaning consisting of a- b carbon atoms, for example, CH 3 SC (O) -group CH 3 CH 2 SC (O)-group, CH 3 CH 2 CH 2 SC (O)-group, (CH 3 ) 2 CHSC (O)-group, CH 3 (CH 2 ) 3 SC (O)-group , (CH 3 ) 2 CHCH 2 SC (O) — group, (CH 3 ) 3 CSC (O) — group, and the like are given as specific examples, and each is selected within the range of the designated number of carbon atoms.

本明細書におけるCa〜Cbアルコキシチオカルボニルの表記は、炭素原子数がa〜b個よりなる前記の意味であるアルキル-O-C(S)-基を表し、例えばCH3OC(S)-基、CH3CH2OC(S)-基、 CH3CH2CH2OC(S)-基、(CH3)2CHOC(S)-基、CH3(CH2)3OC(S)-基、(CH3)2CHCH2OC(S)-基、(CH3)3COC(S)-基等が具体例として挙げられ、各々の指定の炭素原子数の範囲で選択される。 The notation of C a -C b alkoxythiocarbonyl in the present specification represents an alkyl-OC (S) — group having the above-mentioned meaning consisting of a to b carbon atoms, for example, CH 3 OC (S) — Group, CH 3 CH 2 OC (S)-group, CH 3 CH 2 CH 2 OC (S)-group, (CH 3 ) 2 CHOC (S)-group, CH 3 (CH 2 ) 3 OC (S)- Specific examples include a group, (CH 3 ) 2 CHCH 2 OC (S) — group, (CH 3 ) 3 COC (S) — group, etc., and each is selected within the range of the designated number of carbon atoms.

本明細書におけるCa〜Cbアルキルアミノカルボニルの表記は、水素原子の一方が炭素原子数がa〜b個よりなる前記の意味であるアルキル基によって置換されたカルバモイル基を表し、例えばCH3NHC(O)-基、CH3CH2NHC(O)-基、CH3CH2CH2NHC(O)-基、(CH3)2CHNHC(O)-基、CH3(CH2)3NHC(O)-基、(CH3)2CHCH2NHC(O)-基、CH3CH2CH(CH3)NHC(O)-基、(CH3)3CNHC(O)-基等が具体例として挙げられ、各々の指定の炭素原子数の範囲で選択される。 The notation of C a -C b alkylaminocarbonyl in the present specification represents a carbamoyl group in which one of the hydrogen atoms is substituted with an alkyl group having the above-mentioned meaning consisting of a to b carbon atoms, for example, CH 3 NHC (O) - group, CH 3 CH 2 NHC (O ) - group, CH 3 CH 2 CH 2 NHC (O) - group, (CH 3) 2 CHNHC ( O) - group, CH 3 (CH 2) 3 NHC (O)-group, (CH 3 ) 2 CHCH 2 NHC (O)-group, CH 3 CH 2 CH (CH 3 ) NHC (O)-group, (CH 3 ) 3 CNHC (O)-group, etc. Specific examples are given, each selected in the range of the specified number of carbon atoms.

本明細書におけるジ(Ca〜Cbアルキル)アミノカルボニルの表記は、水素原子が両方とも、それぞれ同一でも又は互いに相異なっていてもよい炭素原子数がa〜b個よりなる前記の意味であるアルキル基によって置換されたカルバモイル基を表し、例えば(CH3)2NC(O)-基、CH3CH2N(CH3)C(O)-基、(CH3CH2)2NC(O)-基、(CH3CH2CH2)2NC(O)-基、(CH3CH2CH2CH2)2NC(O)-基等が具体例として挙げられ、各々の指定の炭素原子数の範囲で選択される。 In the present specification, the notation of di (C a -C b alkyl) aminocarbonyl means in the above-mentioned meaning that the number of carbon atoms which may be the same or different from each other is a to b. Represents a carbamoyl group substituted by an alkyl group, for example, a (CH 3 ) 2 NC (O) — group, a CH 3 CH 2 N (CH 3 ) C (O) — group, a (CH 3 CH 2 ) 2 NC ( Specific examples include (O)-group, (CH 3 CH 2 CH 2 ) 2 NC (O)-group, (CH 3 CH 2 CH 2 CH 2 ) 2 NC (O)-group, etc. Selected in the range of the number of carbon atoms.

本明細書におけるCa〜Cbアルキルアミノチオカルボニルの表記は、水素原子の一方が炭素原子数がa〜b個よりなる前記の意味であるアルキル基によって置換されたチオカルバモイル基を表し、例えばCH3NHC(S)-基、CH3CH2NHC(S)-基、CH3CH2CH2NHC(S)-基、(CH3)2CHNHC(S)-基、CH3(CH2)3NHC(S)-基、(CH3)2CHCH2NHC(S)-基、CH3CH2CH(CH3)NHC(S)-基、(CH3)3CNHC(S)-基等が具体例として挙げられ、各々の指定の炭素原子数の範囲で選択される。 In the present specification, the notation of C a -C b alkylaminothiocarbonyl represents a thiocarbamoyl group in which one of the hydrogen atoms is substituted with an alkyl group having the above-mentioned meaning consisting of a to b carbon atoms, for example, CH 3 NHC (S) - group, CH 3 CH 2 NHC (S ) - group, CH 3 CH 2 CH 2 NHC (S) - group, (CH 3) 2 CHNHC ( S) - group, CH 3 (CH 2 ) 3 NHC (S) -group, (CH 3 ) 2 CHCH 2 NHC (S) -group, CH 3 CH 2 CH (CH 3 ) NHC (S) -group, (CH 3 ) 3 CNHC (S) -group Etc. are given as specific examples, and each is selected within the range of the designated number of carbon atoms.

本明細書におけるジ(Ca〜Cbアルキル)アミノチオカルボニルの表記は、水素原子が両方とも、それぞれ同一でも又は互いに相異なっていてもよい炭素原子数がa〜b個よりなる前記の意味であるアルキル基によって置換されたチオカルバモイル基を表し、例えば(CH3)2NC(S)-基、CH3CH2N(CH3)C(S)-基、(CH3CH2)2NC(S)-基、(CH3CH2CH2)2NC(S)-基、(CH3CH2CH2CH2)2NC(S)-基等が具体例として挙げられ、各々の指定の炭素原子数の範囲で選択される。 The notation of di (C a -C b alkyl) aminothiocarbonyl in the present specification means the above-mentioned meaning that the number of carbon atoms that may be the same or different from each other is a to b. Represents a thiocarbamoyl group substituted by an alkyl group such as (CH 3 ) 2 NC (S) — group, CH 3 CH 2 N (CH 3 ) C (S) — group, (CH 3 CH 2 ) 2 Specific examples include NC (S) -group, (CH 3 CH 2 CH 2 ) 2 NC (S) -group, (CH 3 CH 2 CH 2 CH 2 ) 2 NC (S) -group, and the like. Selected within the specified number of carbon atoms.

本明細書におけるCa〜Cbアルキルアミノスルホニルの表記は、水素原子の一方が炭素原子数がa〜b個よりなる前記の意味であるアルキル基によって置換されたスルファモイル基を表し、例えばCH3NHSO2-基、CH3CH2NHSO2-基、CH3CH2CH2NHSO2-基、(CH3)2CHNHSO2-基、CH3(CH2)3NHSO2-基、(CH3)2CHCH2NHSO2-基、CH3CH2CH(CH3)NHSO2-基、(CH3)3CNHSO2-基等が具体例として挙げられ、各々の指定の炭素原子数の範囲で選択される。 The notation of C a -C b alkylaminosulfonyl in the present specification represents a sulfamoyl group in which one of the hydrogen atoms is substituted with an alkyl group having the above-mentioned meaning consisting of a to b carbon atoms, for example, CH 3 NHSO 2 - group, CH 3 CH 2 NHSO 2 - group, CH 3 CH 2 CH 2 NHSO 2 - group, (CH 3) 2 CHNHSO 2 - group, CH 3 (CH 2) 3 NHSO 2 - group, (CH 3 ) 2 CHCH 2 NHSO 2 -group, CH 3 CH 2 CH (CH 3 ) NHSO 2 -group, (CH 3 ) 3 CNHSO 2 -group, etc., are given as specific examples, and within each specified number of carbon atoms Selected.

本明細書におけるジ(Ca〜Cbアルキル)アミノスルホニルの表記は、水素原子が両方とも、それぞれ同一でも又は互いに相異なっていてもよい炭素原子数がa〜b個よりなる前記の意味であるアルキル基によって置換されたスルファモイル基を表し、例えば(CH3)2NSO2-基、CH3CH2N(CH3)SO2-基、(CH3CH2)2NSO2-基、(CH3CH2CH2)2NSO2-基、(CH3CH2CH2CH2)2NSO2-基等が具体例として挙げられ、各々の指定の炭素原子数の範囲で選択される。 In the present specification, the notation of di (C a -C b alkyl) aminosulfonyl means in the above meaning that the number of carbon atoms that may be the same or different from each other is a to b. Represents a sulfamoyl group substituted by an alkyl group, such as (CH 3 ) 2 NSO 2 — group, CH 3 CH 2 N (CH 3 ) SO 2 — group, (CH 3 CH 2 ) 2 NSO 2 — group, ( Specific examples include CH 3 CH 2 CH 2 ) 2 NSO 2 — group, (CH 3 CH 2 CH 2 CH 2 ) 2 NSO 2 — group, etc., and each is selected within the range of the designated number of carbon atoms.

本明細書におけるジ(Ca〜Cbアルキル)ホスホリルの表記は、水素原子が両方とも、それぞれ同一でも又は互いに相異なっていてもよい炭素原子数がa〜b個よりなる前記の意味であるアルキル基によって置換されたホスホリル基を表し、例えば(CH3O)2P(O)-基、(CH3CH2O)2P(O)-基等が具体例として挙げられ、各々の指定の炭素原子数の範囲で選択される。 The notation of di (C a -C b alkyl) phosphoryl in the present specification has the above-mentioned meaning that the number of carbon atoms, which may be both the same or different from each other, consists of a to b. Represents a phosphoryl group substituted by an alkyl group, for example, (CH 3 O) 2 P (O) -group, (CH 3 CH 2 O) 2 P (O) -group, etc. In the range of the number of carbon atoms.

本明細書におけるジ(Ca〜Cbアルキル)チオホスホリルの表記は、水素原子が両方とも、それぞれ同一でも又は互いに相異なっていてもよい炭素原子数がa〜b個よりなる前記の意味であるアルキル基によって置換されたチオホスホリル基を表し、例えば(CH3O)2P(S)-基、(CH3CH2O)2P(S)-基等が具体例として挙げられ、各々の指定の炭素原子数の範囲で選択される。 In the present specification, the notation of di (C a -C b alkyl) thiophosphoryl means in the above-mentioned meaning that the number of carbon atoms which may be the same or different from each other may be ab. Represents a thiophosphoryl group substituted by a certain alkyl group, for example, (CH 3 O) 2 P (S) -group, (CH 3 CH 2 O) 2 P (S) -group, etc. Is selected within the range of the specified number of carbon atoms.

本明細書におけるトリ(Ca〜Cbアルキル)シリルの表記は、それぞれ同一でも又は互いに相異なっていてもよい炭素原子数がa〜b個よりなる前記の意味であるアルキル基によって置換されたシリル基を表し、例えばトリメチルシリル基、トリエチルシリル基、トリ(n-プロピル)シリル基、エチルジメチルシリル基、n-プロピルジメチルシリル基、n-ブチルジメチルシリル基、i-ブチルジメチルシリル基、t-ブチルジメチルシリル基等が具体例として挙げられ、各々の指定の炭素原子数の範囲で選択される。 In the present specification, the notation of tri (C a -C b alkyl) silyl is substituted with an alkyl group having the above-mentioned meanings each having the same or different number of carbon atoms from a to b . Represents a silyl group, for example, trimethylsilyl group, triethylsilyl group, tri (n-propyl) silyl group, ethyldimethylsilyl group, n-propyldimethylsilyl group, n-butyldimethylsilyl group, i-butyldimethylsilyl group, t- Specific examples include a butyldimethylsilyl group and the like, and each butyldimethylsilyl group is selected within a range of each designated number of carbon atoms.

本明細書におけるCa〜Cbアルキルスルホニルオキシの表記は、炭素原子数がa〜b個よりなる前記の意味であるアルキルスルホニル-O-基を表し、例えばCH3SO2-O-基、CH3CH2SO2-O-基、CH3CH2CH2SO2-O-基、(CH3)2CHSO2-O-基、CH3(CH2)3SO2-O-基、(CH3)2CHCH2SO2-O-基、CH3CH2CH(CH3)SO2-O-基、(CH3)3CSO2-O-基等が具体例として挙げられ、各々の指定の炭素原子数の範囲で選択される。 The notation of C a -C b alkylsulfonyloxy in the present specification represents an alkylsulfonyl-O— group having the above-mentioned meaning consisting of a to b carbon atoms, such as a CH 3 SO 2 —O— group, CH 3 CH 2 SO 2 -O- group, CH 3 CH 2 CH 2 SO 2 -O- group, (CH 3 ) 2 CHSO 2 -O- group, CH 3 (CH 2 ) 3 SO 2 -O- group, Specific examples include (CH 3 ) 2 CHCH 2 SO 2 —O— group, CH 3 CH 2 CH (CH 3 ) SO 2 —O— group, (CH 3 ) 3 CSO 2 —O— group, etc. Is selected within the range of the specified number of carbon atoms.

本明細書におけるCa〜Cbハロアルキルスルホニルオキシの表記は、炭素原子数がa〜b個よりなる前記の意味であるハロアルキルスルホニル-O-基を表し、例えばCF3SO2-O-基、CF3CF2SO2-O-基等が具体例として挙げられ、各々の指定の炭素原子数の範囲で選択される。 The notation of C a -C b haloalkylsulfonyloxy in the present specification represents a haloalkylsulfonyl-O— group having the above-mentioned meaning consisting of a to b carbon atoms, such as CF 3 SO 2 —O— group, A CF 3 CF 2 SO 2 —O— group or the like is given as a specific example, and is selected within the range of each designated number of carbon atoms.

本明細書におけるCa〜Cbアルキルスルホニルアミノの表記は、炭素原子数がa〜b個よりなる前記の意味であるアルキルスルホニル-NH-基を表し、例えばCH3SO2-NH-基、CH3CH2SO2-NH-基、CH3CH2CH2SO2-NH-基、(CH3)2CHSO2-NH-基、CH3(CH2)3SO2-NH-基、(CH3)2CHCH2SO2-NH-基、CH3CH2CH(CH3)SO2-NH-基、(CH3)3CSO2-NH-基等が具体例として挙げられ、各々の指定の炭素原子数の範囲で選択される。 The notation of C a -C b alkylsulfonylamino in the present specification represents an alkylsulfonyl-NH— group having the above-mentioned meaning consisting of a to b carbon atoms, for example, CH 3 SO 2 —NH— group, CH 3 CH 2 SO 2 -NH- group, CH 3 CH 2 CH 2 SO 2 -NH- group, (CH 3 ) 2 CHSO 2 -NH- group, CH 3 (CH 2 ) 3 SO 2 -NH- group, Specific examples include (CH 3 ) 2 CHCH 2 SO 2 -NH- group, CH 3 CH 2 CH (CH 3 ) SO 2 -NH- group, (CH 3 ) 3 CSO 2 -NH- group, Is selected within the range of the specified number of carbon atoms.

本明細書におけるCa〜Cbハロアルキルスルホニルアミノの表記は、炭素原子数がa〜b個よりなる前記の意味であるハロアルキルスルホニル-NH-基を表し、例えばCF3SO2-NH-基、CF3CF2SO2-NH-基等が具体例として挙げられ、各々の指定の炭素原子数の範囲で選択される。 The notation of C a -C b haloalkylsulfonylamino in the present specification represents a haloalkylsulfonyl-NH— group having the above-mentioned meaning consisting of a to b carbon atoms, such as CF 3 SO 2 —NH— group, Specific examples include CF 3 CF 2 SO 2 —NH— groups, etc., each selected within the range of the specified number of carbon atoms.

本明細書におけるCa〜Cbシクロアルキル(Cd〜Ce)アルキル、Ca〜Cbアルコキシ(Cd〜Ce)アルキル、Ca〜Cbハロアルコキシ(Cd〜Ce)アルキル、Ca〜Cbアルキルチオ(Cd〜Ce)アルキル、Ca〜Cbハロアルキルチオ(Cd〜Ce)アルキル、Ca〜Cbアルキルスルフィニル(Cd〜Ce)アルキル、Ca〜Cbハロアルキルスルフィニル(Cd〜Ce)アルキル、Ca〜Cbアルキルスルホニル(Cd〜Ce)アルキル、Ca〜Cbハロアルキルスルホニル(Cd〜Ce)アルキル、Ca〜Cbアルキルカルボニル(Cd〜Ce)アルキル、Ca〜Cbハロアルキルカルボニル(Cd〜Ce)アルキル、Ca〜Cbアルコキシカルボニル(Cd〜Ce)アルキル、Ca〜Cbハロアルコキシカルボニル(Cd〜Ce)アルキル、Ca〜Cbアルキルアミノカルボニル(Cd〜Ce)アルキル、ジ(Ca〜Cbアルキル)アミノカルボニル(Cd〜Ce)アルキル、トリ(Ca〜Cbアルキル)シリル(Cd〜Ce)アルキル、フェニル(Cd〜Ce)アルキル、(Z)p1によって置換されたフェニル(Cd〜Ce)アルキル、L-(Cd〜Ce)アルキル又はM-(Cd〜Ce)アルキル等の表記は、それぞれ前記の意味である任意のCa〜Cbシクロアルキル基、Ca〜Cbアルコキシ基、Ca〜Cbハロアルコキシ基、Ca〜Cbアルキルチオ基、Ca〜Cbハロアルキルチオ基、Ca〜Cbアルキルスルフィニル基、Ca〜Cbハロアルキルスルフィニル基、Ca〜Cbアルキルスルホニル基、Ca〜Cbハロアルキルスルホニル基、Ca〜Cbアルキルカルボニル基、Ca〜Cbハロアルキルカルボニル基、Ca〜Cbアルコキシカルボニル基、Ca〜Cbハロアルコキシカルボニル基、Ca〜Cbアルキルアミノカルボニル基、ジ(Ca〜Cbアルキル)アミノカルボニル基、トリ(Ca〜Cbアルキル)シリル基、フェニル基、(Z)p1によって置換されたフェニル基、L基又はM基によって、炭素原子に結合した水素原子が任意に置換された炭素原子数がd〜e個よりなる直鎖状又は分岐鎖状の炭化水素基を表し、各々の指定の炭素原子数の範囲で選択される。 C a -C b cycloalkyl (C d -C e ) alkyl, C a -C b alkoxy (C d -C e ) alkyl, C a -C b haloalkoxy (C d -C e ) alkyl as used herein , C a -C b alkylthio (C d -C e ) alkyl, C a -C b haloalkylthio (C d -C e ) alkyl, C a -C b alkylsulfinyl (C d -C e ) alkyl, C a -C b haloalkylsulfinyl (C d ~C e) alkyl, C a -C b alkylsulfonyl (C d ~C e) alkyl, C a -C b haloalkylsulfonyl (C d ~C e) alkyl, C a -C b alkylcarbonyl (C d -C e ) alkyl, C a -C b haloalkylcarbonyl (C d -C e ) alkyl, C a -C b alkoxycarbonyl (C d -C e ) alkyl, C a -C b halo alkoxycarbonyl (C d -C e) alkyl, C a -C b alkylaminocarbonyl (C d -C e) alkyl, di (C a -C b alkyl) aminocarbonyl (C d C e) alkyl, tri (C a -C b alkyl) silyl (C d -C e) alkyl, phenyl (C d -C e) alkyl, phenyl substituted by (Z) p1 (C d ~C e) The notation such as alkyl, L- (C d -C e ) alkyl or M- (C d -C e ) alkyl is any C a -C b cycloalkyl group, C a -C b , each having the above meaning. Alkoxy group, C a -C b haloalkoxy group, C a -C b alkylthio group, C a -C b haloalkylthio group, C a -C b alkylsulfinyl group, C a -C b haloalkylsulfinyl group, C a- C b alkylsulfonyl group, C a -C b haloalkylsulfonyl group, C a -C b alkylcarbonyl group, C a -C b haloalkylcarbonyl group, C a -C b alkoxycarbonyl group, C a -C b haloalkoxycarbonyl Group, C a -C b alkylaminocarbonyl group, di (C a -C b alkyl) aminocarbonyl group, tri ( C a -C b alkyl) silyl group, phenyl group, phenyl group substituted by (Z) p1 , L group or M group, the hydrogen atom bonded to the carbon atom is arbitrarily substituted by d ~ e represents a linear or branched hydrocarbon group consisting of e, and is selected within the range of the respective designated number of carbon atoms.

本明細書におけるR7によって任意に置換された(Ca〜Cb)アルキル、R16によって任意に置換された(Ca〜Cb)アルキル、R21によって任意に置換された(Ca〜Cb)アルキル、R25によって任意に置換された(Ca〜Cb)アルキル又はR33によって任意に置換された(Ca〜Cb)アルキルの表記は、任意のR7、R16、R21、R25又はR33によって、炭素原子に結合した水素原子が任意に置換された炭素原子数がa〜b個よりなる直鎖状又は分岐鎖状の炭化水素基を表し、各々の指定の炭素原子数の範囲で選択される。このとき、それぞれの(Ca〜Cb)アルキル基上の置換基R7、R16、R21、R25又はR33が２個以上存在するとき、それぞれのR7、R16、R21、R25又はR33は互いに同一でも、または互いに相異なっていてもよい。 Optionally substituted by R 7 herein (C a ~C b) alkyl, optionally substituted by R 16 (C a ~C b) alkyl, optionally substituted by R 21 (C a ~ C b) alkyl, optionally substituted by R 25 (C a ~C b) optionally substituted by alkyl or R 33 (C a ~C b) representation of alkyl, any R 7, R 16, R 21 , R 25 or R 33 represents a linear or branched hydrocarbon group consisting of a to b carbon atoms in which hydrogen atoms bonded to carbon atoms are arbitrarily substituted, and each designation In the range of the number of carbon atoms. At this time, when two or more substituents R 7 , R 16 , R 21 , R 25 or R 33 on each (C a -C b ) alkyl group are present, each R 7 , R 16 , R 21 is present. , R 25 or R 33 may be the same as or different from each other.

本明細書におけるヒドロキシ(Cd〜Ce)ハロアルキル、Ca〜Cbアルコキシ(Cd〜Ce)ハロアルキル又はCa〜Cbハロアルコキシ(Cd〜Ce)ハロアルキルの表記は、水酸基、前記の意味であるCa〜Cbアルコキシ基又は前記の意味であるCa〜Cbハロアルコキシ基によって任意に置換された炭素原子数がd〜e個よりなる前記の意味であるハロアルキル基を表し、例えば2,2,2-トリフルオロ-1-ヒドロキシ-1-(トリフルオロメチル)エチル基、2,2,2-トリフルオロ-1-メトキシ-1-(トリフルオロメチル)エチル基、2,2,2-トリフルオロ-1-(2,2,2-トリフルオロエトキシ)-1-(トリフルオロメチル)エチル基、3-(1,2-ジクロロ-1,2,2-トリフルオロエトキシ)-1,1,2,2,3,3-ヘキサフルオロプロピル基等が具体例として挙げられ、各々の指定の炭素原子数の範囲で選択される。 In the present specification, the notation of hydroxy (C d -C e ) haloalkyl, C a -C b alkoxy (C d -C e ) haloalkyl or C a -C b haloalkoxy (C d -C e ) haloalkyl is a hydroxyl group, A C a -C b alkoxy group as defined above or a haloalkyl group as defined above consisting of d to e carbon atoms optionally substituted by a C a -C b haloalkoxy group as defined above. For example, 2,2,2-trifluoro-1-hydroxy-1- (trifluoromethyl) ethyl group, 2,2,2-trifluoro-1-methoxy-1- (trifluoromethyl) ethyl group, 2 , 2,2-Trifluoro-1- (2,2,2-trifluoroethoxy) -1- (trifluoromethyl) ethyl group, 3- (1,2-dichloro-1,2,2-trifluoroethoxy ) -1,1,2,2,3,3-hexafluoropropyl group and the like are listed as specific examples, and each group is selected within the range of the designated number of carbon atoms.

本明細書におけるR21によって任意に置換された(Ca〜Cb)ハロアルキルの表記は、R21によって任意に置換された炭素原子数がa〜b個よりなる前記の意味であるハロアルキル基を表し、各々の指定の炭素原子数の範囲で選択される。このとき、それぞれの(Ca〜Cb)ハロアルキル基上の置換基R21が２個以上存在するとき、それぞれのR21は互いに同一でも、または互いに相異なっていてもよい。 Optionally substituted by R 21 herein (C a ~C b) notation haloalkyl, a haloalkyl group having a carbon atom number which is optionally substituted by R 21 is the meaning of consisting a~b pieces Selected and selected for each specified number of carbon atoms. At this time, when two or more substituents R 21 on each (C a -C b ) haloalkyl group are present, each R 21 may be the same as or different from each other.

本明細書におけるR7によって任意に置換された(Ca〜Cb)シクロアルキル、R16によって任意に置換された(Ca〜Cb)シクロアルキル、R21によって任意に置換された(Ca〜Cb)シクロアルキル、R25によって任意に置換された(Ca〜Cb)シクロアルキル又はR33によって任意に置換された(Ca〜Cb)シクロアルキル等の表記は、R7、R16、R21、R25又はR33によって任意に置換された炭素原子数がa〜b個よりなる前記の意味であるシクロアルキル基を表す。このとき、R7、R16、R21、R25又はR33による置換は、環構造部分であっても、側鎖部分であっても、或いはそれらの両方であってもよく、さらに、それぞれの(Ca〜Cb)シクロアルキル基上の置換基R7、R16、R21、R25又はR33が２個以上存在するとき、それぞれのR7、R16、R21、R25又はR33は互いに同一でも、または互いに相異なっていてもよい。 The R 7 herein optionally substituted (C a ~C b) cycloalkyl, optionally substituted by R 16 (C a ~C b) cycloalkyl, optionally substituted by R 21 (C a -C b) cycloalkyl, notation (C a ~C b) cycloalkyl such as optionally substituted by optionally substituted (C a ~C b) cycloalkyl or R 33 by R 25 is, R 7 , R 16 , R 21 , R 25 or R 33 represents a cycloalkyl group having the above-mentioned meaning consisting of a to b carbon atoms. At this time, the substitution by R 7 , R 16 , R 21 , R 25 or R 33 may be a ring structure part, a side chain part or both, and When two or more substituents R 7 , R 16 , R 21 , R 25 or R 33 on the (C a -C b ) cycloalkyl group are present, each R 7 , R 16 , R 21 , R 25 Alternatively, R 33 may be the same as or different from each other.

本明細書におけるR21によって任意に置換された(Ca〜Cb)ハロシクロアルキルの表記は、R21によって任意に置換された炭素原子数がa〜b個よりなる前記の意味であるハロシクロアルキル基を表す。このとき、R21による置換は、環構造部分であっても、側鎖部分であっても、或いはそれらの両方であってもよく、さらに、それぞれの(Ca〜Cb)ハロシクロアルキル基上の置換基R21が２個以上存在するとき、それぞれのR21は互いに同一でも、または互いに相異なっていてもよい。 Herein is optionally substituted by R 21 (C a ~C b) representation of halocycloalkyl are defined above in which the carbon atoms which is optionally substituted by R 21 is composed of a~b number halo Represents a cycloalkyl group. At this time, the substitution by R 21 may be a ring structure part, a side chain part, or both of them, and each (C a -C b ) halocycloalkyl group. When two or more of the above substituents R 21 are present, each R 21 may be the same as or different from each other.

本明細書におけるフェニル(Cd〜Ce)アルケニル又は(Z)p1によって置換されたフェニル(Cd〜Ce)アルケニル等の表記は、それぞれ前記の意味であるフェニル基又は(Z)p1によって置換されたフェニル基によって任意に置換された炭素原子数がd〜e個よりなる前記の意味であるアルケニル基を表し、各々の指定の炭素原子数の範囲で選択される。 Notation such as phenyl (C d ~C e) alkenyl substituted by phenyl (C d ~C e) alkenyl or (Z) p1 in the present specification, by a phenyl group or (Z) p1 is a meaning of each of the It represents an alkenyl group having the above-mentioned meaning consisting of d to e carbon atoms optionally substituted with a substituted phenyl group, and is selected in the range of each designated number of carbon atoms.

本明細書におけるR7によって任意に置換された(Ca〜Cb)アルケニル、R16によって任意に置換された(Ca〜Cb)アルケニル、R21によって任意に置換された(Ca〜Cb)アルケニル、R25によって任意に置換された(Ca〜Cb)アルケニル又はR33によって任意に置換された(Ca〜Cb)アルケニルの表記は、R7、R16、R21、R25又はR33によって任意に置換された炭素原子数がa〜b個よりなる前記の意味であるアルケニル基を表し、各々の指定の炭素原子数の範囲で選択される。このとき、それぞれの(Ca〜Cb)アルケニル基上の置換基R7、R16、R21、R25又はR33が２個以上存在するとき、それぞれのR7、R16、R21、R25又はR33は互いに同一でも、または互いに相異なっていてもよい。 Optionally substituted by R 7 herein (C a ~C b) alkenyl, optionally substituted by R 16 (C a ~C b) alkenyl, optionally substituted by R 21 (C a ~ C b) alkenyl, optionally substituted by R 25 (C a ~C b) optionally substituted by alkenyl or R 33 (C a ~C b) notation alkenyl, R 7, R 16, R 21 , R 25 or R 33 represents an alkenyl group having the above-mentioned meaning, wherein the number of carbon atoms is optionally substituted by a to b, and is selected in the range of each designated number of carbon atoms. At this time, when two or more substituents R 7 , R 16 , R 21 , R 25 or R 33 on each (C a -C b ) alkenyl group are present, each R 7 , R 16 , R 21 is present. , R 25 or R 33 may be the same as or different from each other.

本明細書におけるフェニル(Cd〜Ce)アルキニル又は(Z)p1によって置換されたフェニル(Cd〜Ce)アルキニルの表記は、フェニル基又は(Z)p1によって置換されたフェニル基によって任意に置換された炭素原子数がd〜e個よりなる前記の意味であるアルキニル基を表し、各々の指定の炭素原子数の範囲で選択される。 Phenyl (C d ~C e) notation alkynyl or (Z) phenyl substituted by p1 (C d ~C e) alkynyl herein, optionally by phenyl substituted by phenyl or (Z) p1 Represents an alkynyl group having the above-mentioned meaning, wherein the number of carbon atoms substituted is from d to e, and is selected within the range of each designated number of carbon atoms.

本明細書におけるR7によって任意に置換された(Ca〜Cb)アルキニル、R16によって任意に置換された(Ca〜Cb)アルキニル、R21によって任意に置換された(Ca〜Cb)アルキニル、R25によって任意に置換された(Ca〜Cb)アルキニル又はR33によって任意に置換された(Ca〜Cb)アルキニルの表記は、R7、R16、R21、R25又はR33によって任意に置換された炭素原子数がa〜b個よりなる前記の意味であるアルキニル基を表し、各々の指定の炭素原子数の範囲で選択される。このとき、それぞれの(Ca〜Cb)アルキニル基上の置換基R7、R16、R21、R25又はR33が２個以上存在するとき、それぞれのR7、R16、R21、R25又はR33は互いに同一でも、または互いに相異なっていてもよい。 Optionally substituted by R 7 herein (C a ~C b) alkynyl, optionally substituted by R 16 (C a ~C b) alkynyl, optionally substituted by R 21 (C a ~ C b) alkynyl, optionally substituted by R 25 (C a ~C b) optionally substituted by alkynyl, or R 33 (C a ~C b) notation alkynyl, R 7, R 16, R 21 , R 25 or R 33 represents an alkynyl group having the above-mentioned meaning, wherein the number of carbon atoms is optionally substituted by a to b, and is selected in the range of each designated number of carbon atoms. At this time, when two or more substituents R 7 , R 16 , R 21 , R 25 or R 33 on each (C a -C b ) alkynyl group are present, each R 7 , R 16 , R 21 is present. , R 25 or R 33 may be the same as or different from each other.

本明細書におけるフェニル(Ca〜Cb)アルコキシ又は(Z)p1によって置換されたフェニル(Ca〜Cb)アルコキシの表記は、フェニル基又は(Z)p1によって置換されたフェニル基によって任意に置換された前記の意味である(Ca〜Cb)アルコキシ基を表し、(Ca〜Cb)アルコキシ基として例えば-CH2O-基、-CH(CH3)O-基、-C(CH3)2O-基、-CH2CH2O-基、-CH(CH3)CH2O-基、-C(CH3)2CH2O-基等が具体例として挙げられ、各々の指定の炭素原子数の範囲で選択される。 Phenyl (C a ~C b) notation alkoxy or (Z) phenyl substituted by p1 (C a ~C b) alkoxy in the present specification is arbitrarily by a phenyl group substituted by a phenyl group or (Z) p1 Represents a (C a -C b ) alkoxy group as defined above, and the (C a -C b ) alkoxy group includes, for example, a —CH 2 O— group, a —CH (CH 3 ) O— group, — Specific examples include C (CH 3 ) 2 O— group, —CH 2 CH 2 O— group, —CH (CH 3 ) CH 2 O— group, —C (CH 3 ) 2 CH 2 O— group and the like. , Each selected range of carbon atoms.

本明細書におけるCa〜Cbハロアルコキシ(Cd〜Ce)ハロアルコキシの表記は、前記の意味であるCa〜Cbハロアルコキシ基によって任意に置換された炭素原子数がd〜e個よりなる前記の意味であるハロアルコキシ基を表し、例えば1,1,2-トリフルオロ-2-トリフルオロメトキシエトキシ基、1,1,2-トリフルオロ-2-ヘプタフルオロプロピルオキシエトキシ基等が具体例として挙げられ、各々の指定の炭素原子数の範囲で選択される。 In the present specification, C a -C b haloalkoxy (C d -C e ) haloalkoxy is represented by the number of carbon atoms optionally substituted by the C a -C b haloalkoxy group as defined above being d- e Represents a haloalkoxy group having the above-mentioned meaning, such as 1,1,2-trifluoro-2-trifluoromethoxyethoxy group, 1,1,2-trifluoro-2-heptafluoropropyloxyethoxy group, etc. Are given as specific examples and are selected in the range of each designated number of carbon atoms.

本明細書におけるフェニル(Ca〜Cb)アルキルカルボニル又は(Z)p1によって置換されたフェニル(Ca〜Cb)アルキルカルボニルの表記は、フェニル基又は(Z)p1によって置換されたフェニル基によって任意に置換された前記の意味である(Ca〜Cb)アルキルカルボニル基を表し、(Ca〜Cb)アルキルカルボニル基として例えば-CH2C(O)-基、-CH(CH3)C(O)-基、-C(CH3)2C(O)-基、-CH2CH2C(O)-基、-CH(CH3)CH2C(O)-基、-C(CH3)2CH2C(O)-基、-CH2CH(CH3)C(O)-基、-CH2C(CH3)2C(O)-基、-CH2CH2CH2C(O)-基等が具体例として挙げられ、各々の指定の炭素原子数の範囲で選択される。 Phenyl notation (C a ~C b) phenyl substituted by alkylcarbonyl or (Z) p1 (C a ~C b) alkylcarbonyl herein, a phenyl group substituted by a phenyl group or (Z) p1 Represents a (C a -C b ) alkylcarbonyl group having the above meaning optionally substituted by, for example, as a (C a -C b ) alkylcarbonyl group, for example, a —CH 2 C (O) — group, —CH (CH 3 ) C (O)-group, -C (CH 3 ) 2 C (O)-group, -CH 2 CH 2 C (O)-group, -CH (CH 3 ) CH 2 C (O)-group, -C (CH 3 ) 2 CH 2 C (O)-group, -CH 2 CH (CH 3 ) C (O)-group, -CH 2 C (CH 3 ) 2 C (O)-group, -CH 2 Specific examples include CH 2 CH 2 C (O) — groups and the like, each selected within the range of the specified number of carbon atoms.

本明細書におけるフェニル(Ca〜Cb)アルコキシカルボニル又は(Z)p1によって置換されたフェニル(Ca〜Cb)アルコキシカルボニルの表記は、フェニル基又は(Z)p1によって置換されたフェニル基によって任意に置換された前記の意味である(Ca〜Cb)アルコキシカルボニル基を表し、(Ca〜Cb)アルコキシカルボニル基として例えば-CH2O-C(O)-基、-CH(CH3)O-C(O)-基、-C(CH3)2O-C(O)-基、-CH2CH2O-C(O)-基、-CH(CH3)CH2O-C(O)-基、-C(CH3)2CH2O-C(O)-基等が具体例として挙げられ、各々の指定の炭素原子数の範囲で選択される。 Representation of substituted phenyl (C a ~C b) alkoxycarbonyl by phenyl (C a ~C b) alkoxycarbonyl or (Z) p1 in the present specification, a phenyl group substituted by a phenyl group or (Z) p1 Represents a (C a -C b ) alkoxycarbonyl group having the above meaning optionally substituted by, for example, a (C a -C b ) alkoxycarbonyl group such as a —CH 2 OC (O) — group, —CH (CH 3 ) OC (O)-group, -C (CH 3 ) 2 OC (O)-group, -CH 2 CH 2 OC (O)-group, -CH (CH 3 ) CH 2 OC (O)-group, Specific examples include —C (CH 3 ) 2 CH 2 OC (O) — group and the like, and each is selected within the range of the number of carbon atoms specified.

本明細書における
[R2はR1と一緒になってC2〜C6アルキレン鎖を形成することにより、結合する窒素原子と共に３〜７員環を形成してもよいことを表し、このときこのアルキレン鎖は酸素原子、硫黄原子又は窒素原子を１個含んでもよく、]、
[R17とR18とが一緒になってC4〜C7アルキレン鎖を形成することにより、結合する窒素原子と共に５〜８員環を形成してもよいことを表し、このときこのアルキレン鎖は酸素原子又は硫黄原子を１個含んでもよく、]、
[R26とR27とが一緒になってC2〜C5アルキレン鎖を形成することにより、結合する窒素原子と共に３〜６員環を形成してもよいことを表し、このときこのアルキレン鎖は酸素原子又は硫黄原子を１個含んでもよく、]、
[R29とR30とが一緒になってC2〜C5アルキレン鎖を形成することにより、結合する窒素原子と共に３〜６員環を形成してもよいことを表し、このときこのアルキレン鎖は酸素原子、硫黄原子又は窒素原子を１個含んでもよく、]、
及び
[R34とR35とが一緒になってC2〜C5アルキレン鎖を形成することにより、結合する窒素原子と共に３〜６員環を形成してもよいことを表し、このときこのアルキレン鎖は酸素原子又は硫黄原子を１個含んでもよく、]
の表記の具体例として、例えばアジリジン、アゼチジン、ピロリジン、オキサゾリジン、チアゾリジン、イミダゾリジン、ピペリジン、モルホリン、チオモルホリン、ピペラジン、ホモピペリジン、ヘプタメチレンイミン等が挙げられ、各々の指定の原子数の範囲で選択される。 In this specification
[R 2 represents that, together with R 1 , a C 2 -C 6 alkylene chain may be formed to form a 3- to 7-membered ring with the nitrogen atom to which the alkylene chain is bonded. May contain one oxygen atom, sulfur atom or nitrogen atom,
[R 17 and R 18 together form a C 4 to C 7 alkylene chain to form a 5- to 8-membered ring together with the nitrogen atom to which the alkylene chain is bonded. May contain one oxygen or sulfur atom,
[Represents that R 26 and R 27 may form a C 2 -C 5 alkylene chain together to form a 3- to 6-membered ring together with the nitrogen atom to which the R 26 and R 27 are bonded. May contain one oxygen or sulfur atom,
[Represents that R 29 and R 30 together form a C 2 -C 5 alkylene chain to form a 3- to 6-membered ring together with the nitrogen atom to which the alkylene chain is bonded. May contain one oxygen, sulfur or nitrogen atom,
as well as
[Represents that R 34 and R 35 together form a C 2 -C 5 alkylene chain to form a 3- to 6-membered ring with the nitrogen atom to which it is bonded. May contain one oxygen or sulfur atom,
Specific examples of the notation include, for example, aziridine, azetidine, pyrrolidine, oxazolidine, thiazolidine, imidazolidine, piperidine, morpholine, thiomorpholine, piperazine, homopiperidine, heptamethyleneimine, etc. Selected.

本明細書における
[R9とR10とが一緒になってC2〜C6アルキレン鎖を形成することにより、結合する原子と共に３〜７員環を形成してもよいことを表し、このときこのアルキレン鎖は酸素原子、硫黄原子又は窒素原子を１個含んでもよく、]
の表記の具体例として、例えばアジリジン、アゼチジン、アゼチジン-2-オン、ピロリジン、ピロリジン-2-オン、オキサゾリジン、オキサゾリジン-2-オン、チアゾリジン、チアゾリジン-2-オン、イミダゾリジン、イミダゾリジン-2-オン、ピペリジン、ピペリジン-2-オン、モルホリン、テトラヒドロ-1,3-オキサジン-2-オン、チオモルホリン、テトラヒドロ-1,3-チアジン-2-オン、ピペラジン、テトラヒドロピリミジン-2-オン、ホモピペリジン、ホモピペリジン-2-オン等が挙げられ、各々の指定の原子数の範囲で選択される。 In this specification
[R 9 and R 10 together form a C 2 to C 6 alkylene chain, which indicates that a 3 to 7 membered ring may be formed with the atoms to be bonded. May contain one oxygen, sulfur or nitrogen atom,
Specific examples of the notation include, for example, aziridine, azetidine, azetidin-2-one, pyrrolidine, pyrrolidin-2-one, oxazolidine, oxazolidine-2-one, thiazolidine, thiazolidine-2-one, imidazolidine, imidazolidine-2- ON, piperidine, piperidin-2-one, morpholine, tetrahydro-1,3-oxazin-2-one, thiomorpholine, tetrahydro-1,3-thiazin-2-one, piperazine, tetrahydropyrimidin-2-one, homopiperidine , Homopiperidin-2-one and the like, and each is selected within the range of the designated number of atoms.

本明細書における
[R11はR9と一緒になってC2〜C4アルキレン鎖を形成することにより、結合する原子と共に５〜７員環を形成してもよいことを表し、このときこのアルキレン鎖は酸素原子、硫黄原子又は窒素原子を１個含んでもよく、]
の表記の具体例として、例えばイソキサゾリン、1,4,2-ジオキサゾリン、1,4,2-オキサチアゾリン、1,2,4-オキサジアゾリン、ジヒドロ-1,2-オキサジン、ジヒドロ-1,4,2-ジオキサジン、ジヒドロ-1,4,2-オキサチアジン、ジヒドロ-4H-1,2,4-オキサジアジン、テトラヒドロ-1,2-オキサゼピン等が挙げられ、各々の指定の原子数の範囲で選択される。 In this specification
[R 11 represents that, together with R 9 , a C 2 -C 4 alkylene chain may be formed to form a 5- to 7-membered ring with the atoms to be bonded. May contain one atom, sulfur atom or nitrogen atom,
Specific examples of the notation include, for example, isoxazoline, 1,4,2-dioxazoline, 1,4,2-oxathiazoline, 1,2,4-oxadiazoline, dihydro-1,2-oxazine, dihydro-1, 4,2-dioxazine, dihydro-1,4,2-oxathiazine, dihydro-4H-1,2,4-oxadiazine, tetrahydro-1,2-oxazepine, etc. are selected, each selected within the specified number of atoms Is done.

本発明に包含される化合物において、W1又はW2で表される置換基として、例えば酸素原子又は硫黄原子が挙げられ、これらのうち酸素原子が好ましい。 In the compounds included in the present invention, examples of the substituent represented by W 1 or W 2 include an oxygen atom or a sulfur atom, and among these, an oxygen atom is preferable.

本発明に包含される化合物において、Xで表される置換基の範囲として、例えば下記の各群が挙げられる。このとき、下記のそれぞれの場合においてmが２以上の整数を表すとき、各々のXは互いに同一であっても又は互いに相異なっていてもよい。   In the compounds included in the present invention, examples of the range of the substituent represented by X include the following groups. At this time, when m represents an integer of 2 or more in each of the following cases, each X may be the same as or different from each other.

すなわち、X-I：ハロゲン原子。   That is, X-I: a halogen atom.

X-II：シアノ及びニトロ。   X-II: cyano and nitro.

X-III：C1〜C6アルキル及びC1〜C6ハロアルキル。 X-III: C 1 ~C 6 alkyl and C 1 -C 6 haloalkyl.

X-IV：C1〜C6アルコキシ、C1〜C6ハロアルコキシ及びC1〜C6アルキルスルホニルオキシ。 X-IV: C 1 ~C 6 alkoxy, C 1 -C 6 haloalkoxy and C 1 -C 6 alkylsulfonyloxy.

X-V：C1〜C6アルキルチオ、C1〜C6ハロアルキルチオ、C1〜C6アルキルスルフィニル、C1〜C6ハロアルキルスルフィニル、C1〜C6アルキルスルホニル及びC1〜C6ハロアルキルスルホニル。 XV: C 1 ~C 6 alkylthio, C 1 -C 6 haloalkylthio, C 1 -C 6 alkylsulfinyl, C 1 -C 6 haloalkylsulfinyl, C 1 -C 6 alkylsulfonyl and C 1 -C 6 haloalkylsulfonyl.

X-VI：mが２以上の整数を表し、且つ、２つのXが隣接し、さらに隣接する２つのXが-OCH2O-又は-OCH2CH2O-を形成することにより、それぞれが結合する炭素原子と共に５員環又は６員環を形成。このとき、環を形成する各々の炭素原子に結合した水素原子はハロゲン原子、C1〜C4アルキル基又はC1〜C4ハロアルキル基によって任意に置換されていてもよい。 X-VI: m represents an integer of 2 or more, two Xs are adjacent, and two adjacent Xs form —OCH 2 O— or —OCH 2 CH 2 O— Forms a 5- or 6-membered ring with the carbon atom to which it is attached. In this case, a hydrogen atom is a halogen atom attached to each carbon atom forming the ring may be optionally substituted by C 1 -C 4 alkyl or C 1 -C 4 haloalkyl group.

本発明に包含される化合物において、Xで表される置換基の数を表すmとしては０〜４の整数が挙げられ、これらのうちmは０，１及び２が好ましい。   In the compound included in the present invention, m representing the number of substituents represented by X includes an integer of 0 to 4. Among these, m is preferably 0, 1 or 2.

本発明に包含される化合物において、Yで表される置換基の範囲として、例えば下記の各群が挙げられる。このとき、下記のそれぞれの場合においてnが２以上の整数を表すとき、各々のYは互いに同一であっても又は互いに相異なっていてもよい。   In the compounds included in the present invention, examples of the range of the substituent represented by Y include the following groups. At this time, when n represents an integer of 2 or more in each of the following cases, each Y may be the same as or different from each other.

すなわち、Y-I：ハロゲン原子。   That is, Y-I: a halogen atom.

Y-II：C1〜C6アルキル。 Y-II: C 1 ~C 6 alkyl.

Y-III：C1〜C6ハロアルキル、ヒドロキシ(C1〜C6)アルキル及びC1〜C4アルコキシ(C1〜C4)アルキル。 Y-III: C 1 ~C 6 haloalkyl, hydroxy (C 1 ~C 6) alkyl and C 1 -C 4 alkoxy (C 1 ~C 4) alkyl.

Y-IV：C1〜C6アルコキシ及びC1〜C6ハロアルコキシ。 Y-IV: C 1 ~C 6 alkoxy and C 1 -C 6 haloalkoxy.

Y-V：C1〜C6アルキルチオ及びC1〜C6ハロアルキルチオ。 YV: C 1 ~C 6 alkylthio and C 1 -C 6 haloalkylthio.

Y-VI：C1〜C6アルキルアミノ及びジ(C1〜C6アルキル)アミノ。 Y-VI: C 1 ~C 6 alkyl amino and di (C 1 -C 6 alkyl) amino.

本発明に包含される化合物において、Yで表される置換基の数を表すnとしては０〜４の整数が挙げられ、これらのうちnは０，１及び２が好ましい。   In the compounds included in the present invention, n representing the number of substituents represented by Y includes an integer of 0 to 4, and among these, n is preferably 0, 1 or 2.

本発明に包含される化合物において、R1で表される置換基の範囲として、例えば下記の各群が挙げられる。 In the compounds included in the present invention, examples of the range of the substituent represented by R 1 include the following groups.

すなわち、R1-I：C1〜C8アルキル及びC3〜C8シクロアルキル。 That is, R 1 -I: C 1 -C 8 alkyl and C 3 -C 8 cycloalkyl.

R1-II：-OR26によって任意に置換されたC1〜C8アルキル［ここで、R26はC1〜C6アルキル、C1〜C6アルキルアミノカルボニル又はジ(C1〜C6アルキル)アミノカルボニルを表す。］。 R 1 -II: C 1 -C 8 alkyl optionally substituted by —OR 26 [where R 26 is C 1 -C 6 alkyl, C 1 -C 6 alkylaminocarbonyl or di (C 1 -C 6 Alkyl) aminocarbonyl. ].

R1-III：-CH=NOH又は-CH=NOR31によって任意に置換されたC1〜C8アルキル［ここで、R31はC1〜C6アルキルを表す。］。 R 1 -III: C 1 -C 8 alkyl optionally substituted by —CH═NOH or —CH═NOR 31 [where R 31 represents C 1 -C 6 alkyl. ].

R1-IV：R16によって任意に置換されたC1〜C8アルキル［ここで、R16は-OR26を表し、R26は水素原子、C1〜C6アルキル、C1〜C6ハロアルキル、C1〜C4アルコキシ(C1〜C4)アルキル、C1〜C4アルキルチオ(C1〜C4)アルキル、フェニル(C1〜C4)アルキル、(Z)p1によって置換されたフェニル(C1〜C4)アルキル、C1〜C6アルキルカルボニル、C1〜C6ハロアルキルカルボニル、C3〜C6シクロアルキルカルボニル、-C(O)N(R30)R29、ジ(C1〜C6アルキル)ホスホリル、ジ(C1〜C6アルキル)チオホスホリル、トリ(C1〜C4アルキル)シリル、フェニル又は(Z)p1によって置換されたフェニルを表し、R29はC1〜C6アルキル、C1〜C4アルコキシ(C1〜C4)アルキル、C1〜C4アルキルチオ(C1〜C4)アルキル、フェニル(C1〜C4)アルキル、(Z)p1によって置換されたフェニル(C1〜C4)アルキル、C3〜C6シクロアルキル、C3〜C6アルケニル、C3〜C6アルキニル、フェニル又は(Z)p1によって置換されたフェニルを表し、R30は水素原子又はC1〜C6アルキルを表すか、或いは、R29とR30とが一緒になってC2〜C5アルキレン鎖を形成することにより、結合する窒素原子と共に３〜６員環を形成してもよいことを表し、このときこのアルキレン鎖は酸素原子又は硫黄原子を１個含んでもよいことを表す。］、M-4、M-5、M-14、M-15及びM-16。 R 1 -IV: in C 1 -C 8 alkyl [wherein optionally substituted by R 16, R 16 represents -OR 26, R 26 is a hydrogen atom, C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, C 1 -C 4 alkoxy (C 1 ~C 4) alkyl, C 1 -C 4 alkylthio (C 1 ~C 4) alkyl, phenyl (C 1 ~C 4) alkyl, substituted by (Z) p1 phenyl (C 1 -C 4) alkyl, C 1 -C 6 alkylcarbonyl, C 1 -C 6 haloalkylcarbonyl, C 3 -C 6 cycloalkylcarbonyl, -C (O) N (R 30) R 29, di ( C 1 -C 6 alkyl) represents phosphoryl, di (C 1 -C 6 alkyl) thiophosphoryl, tri (C 1 -C 4 alkyl) silyl, phenyl substituted by phenyl or (Z) p1, R 29 is C 1 -C 6 alkyl, C 1 -C 4 alkoxy (C 1 ~C 4) alkyl, C 1 -C 4 alkylthio (C 1 ~C 4) alkyl, phenyl (C 1 ~C 4) alkyl, (Z) p1 Replaced by Alkylsulfonyl (C 1 ~C 4) represents alkyl, C 3 -C 6 cycloalkyl, C 3 -C 6 alkenyl, C 3 -C 6 alkynyl, phenyl substituted by phenyl or (Z) p1, R 30 is hydrogen or represents an atom or C 1 -C 6 alkyl, or, by the R 29 and R 30 form a C 2 -C 5 alkylene chain together, form a 3-6 membered ring together with the nitrogen atom attached In this case, this alkylene chain may contain one oxygen atom or sulfur atom. ], M-4, M-5, M-14, M-15 and M-16.

R1-V：R16によって任意に置換されたC1〜C8アルキル［ここで、R16はシアノ、C1〜C6アルコキシカルボニル、C1〜C6アルキルアミノカルボニル、ジ(C1〜C6アルキル)アミノカルボニル、-C(R32)=NOH又は-C(R32)=NOR31を表し、R31はC1〜C6アルキル、フェニル(C1〜C4)アルキル又は(Z)p1によって置換されたフェニル(C1〜C4)アルキルを表し、R32は水素原子又はC1〜C6アルキルを表す。］。 R 1 -V: by R 16 C 1 ~C 8 alkyl [wherein optionally substituted, R 16 is cyano, C 1 -C 6 alkoxycarbonyl, C 1 -C 6 alkylaminocarbonyl, di (C 1 ~ C 6 alkyl) aminocarbonyl, represents -C (R 32) = NOH or -C (R 32) = NOR 31 , R 31 is C 1 -C 6 alkyl, phenyl (C 1 -C 4) alkyl or (Z ) represents phenyl (C 1 -C 4 ) alkyl substituted by p 1 , and R 32 represents a hydrogen atom or C 1 -C 6 alkyl. ].

R1-VI：R16によって任意に置換されたC1〜C8アルキル［ここで、R16はハロゲン原子、C3〜C6シクロアルキル、トリ(C1〜C6アルキル)シリル、フェニル、(Z)p1によって置換されたフェニル、L-1、L-2、L-3、L-4、L-45、L-46、L-47又はMを表す。］。 R 1 -VI: optionally substituted C 1 -C 8 alkyl [wherein the R 16, R 16 is a halogen atom, C 3 -C 6 cycloalkyl, tri (C 1 -C 6 alkyl) silyl, phenyl, (Z) represents phenyl, L-1, L-2, L-3, L-4, L-45, L-46, L-47 or M substituted by p1 . ].

R1-VII：C1〜C6アルキル、C1〜C4アルキルチオ(C1〜C4)アルキル、C1〜C4アルキルスルフィニル(C1〜C4)アルキル及びC1〜C4アルキルスルホニル(C1〜C4)アルキル。 R 1 -VII: C 1 ~C 6 alkyl, C 1 -C 4 alkylthio (C 1 ~C 4) alkyl, C 1 -C 4 alkylsulfinyl (C 1 ~C 4) alkyl and C 1 -C 4 alkylsulfonyl (C 1 ~C 4) alkyl.

R1-VIII：C3〜C8アルケニル及びC3〜C8アルキニル。 R 1 -VIII: C 3 ~C 8 alkenyl and C 3 -C 8 alkynyl.

R1-IX：C1〜C4アルキルチオ(C1〜C4)アルキル、C1〜C4アルキルスルフィニル(C1〜C4)アルキル及びC1〜C4アルキルスルホニル(C1〜C4)アルキル。 R 1 -IX: C 1 -C 4 alkylthio (C 1 -C 4 ) alkyl, C 1 -C 4 alkylsulfinyl (C 1 -C 4 ) alkyl and C 1 -C 4 alkylsulfonyl (C 1 -C 4 ) Alkyl.

R1-X：-N(R27)R26によって任意に置換された(C1〜C8)アルキル［ここで、R26はC1〜C6アルコキシカルボニル、C1〜C6アルキルスルホニル又はジ(C1〜C6アルキル)チオホスホリルを表し、R27は水素原子又はC1〜C6アルキルを表す。］。 R 1 -X: (C 1 -C 8 ) alkyl optionally substituted by —N (R 27 ) R 26 , wherein R 26 is C 1 -C 6 alkoxycarbonyl, C 1 -C 6 alkylsulfonyl or It represents di (C 1 -C 6 alkyl) thiophosphoryl, and R 27 represents a hydrogen atom or C 1 -C 6 alkyl. ].

R1-XI：R16によって任意に置換されたC1〜C8アルキル［ここで、R16は-S(O)rR28又は-SO2N(R30)R29を表し、R28はC1〜C6アルキル、C1〜C6ハロアルキル、ヒドロキシ(C1〜C4)アルキル、C1〜C4アルコキシ(C1〜C4)アルキル、C1〜C4アルキルチオ(C1〜C4)アルキル、C1〜C4アルキルカルボニル(C1〜C4)アルキル、C1〜C4アルコキシカルボニル(C1〜C4)アルキル、C1〜C4アルキルアミノカルボニル(C1〜C4)アルキル、ジ(C1〜C4アルキル)アミノカルボニル(C1〜C4)アルキル、トリ(C1〜C4アルキル)シリル(C1〜C4)アルキル、フェニル(C1〜C4)アルキル、(Z)p1によって置換されたフェニル(C1〜C4)アルキル、C3〜C6アルケニル、C3〜C6アルキニル、C1〜C6アルキルチオ、フェニル、(Z)p1によって置換されたフェニル、L-21、L-35、L-45又はL-48を表し、rは０〜２の整数を表し、R29はC1〜C6アルキルを表し、R30は水素原子又はC1〜C6アルキルを表す。］、M-8、M-9、M-17、M-18及びM-19。 R 1 -XI: C 1 ~C 8 alkyl [wherein optionally substituted by R 16, R 16 represents -S (O) r R 28 or -SO 2 N (R 30) R 29, R 28 the C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, hydroxy (C 1 ~C 4) alkyl, C 1 -C 4 alkoxy (C 1 ~C 4) alkyl, C 1 -C 4 alkylthio (C 1 ~ C 4) alkyl, C 1 -C 4 alkylcarbonyl (C 1 ~C 4) alkyl, C 1 -C 4 alkoxycarbonyl (C 1 ~C 4) alkyl, C 1 -C 4 alkylaminocarbonyl (C 1 -C 4) alkyl, di (C 1 -C 4 alkyl) aminocarbonyl (C 1 -C 4) alkyl, tri (C 1 -C 4 alkyl) silyl (C 1 -C 4) alkyl, phenyl (C 1 -C 4 ) substituted alkyl, by (Z) phenyl substituted by p1 (C 1 ~C 4) alkyl, C 3 -C 6 alkenyl, C 3 -C 6 alkynyl, C 1 -C 6 alkylthio, phenyl, (Z) p1 Phenyl, L-21, L-35, L-45 or L-4 8, r represents an integer of 0 to 2, R 29 represents C 1 to C 6 alkyl, and R 30 represents a hydrogen atom or C 1 to C 6 alkyl. ], M-8, M-9, M-17, M-18 and M-19.

R1-XII：R16によって任意に置換されたC1〜C8アルキル［ここで、R16は-N(R27)R26を表し、R26はC1〜C6アルキルカルボニル、C3〜C6シクロアルキルカルボニル、C1〜C6アルコキシカルボニル、ジ(C1〜C6アルキル)アミノカルボニル、C1〜C6アルキルスルホニル、ジ(C1〜C6アルキル)アミノスルホニル、フェニルスルホニル、(Z)p1によって置換されたフェニルスルホニル又はジ(C1〜C6アルキル)チオホスホリルを表し、R27は水素原子又はC1〜C6アルキルを表す。］、M-13、M-21及びM-22。 R 1 XII: by R 16 is C 1 -C 8 alkyl [here was an optionally substituted, R 16 represents -N (R 27) R 26, R 26 is C 1 -C 6 alkylcarbonyl, C 3 -C 6 cycloalkylcarbonyl, C 1 -C 6 alkoxycarbonyl, di (C 1 -C 6 alkyl) aminocarbonyl, C 1 -C 6 alkylsulfonyl, di (C 1 -C 6 alkyl) aminosulfonyl, phenylsulfonyl, (Z) represents phenylsulfonyl or di (C 1 -C 6 alkyl) thiophosphoryl substituted by p 1 , and R 27 represents a hydrogen atom or C 1 -C 6 alkyl. ], M-13, M-21 and M-22.

R1-XIII：R1とR2とが一緒になって形成する３〜７員環がアジリジン、アゼチジン、ピロリジン、オキサゾリジン、チアゾリジン、ピペリジン、モルホリン、チオモルホリン及びホモピペリジン。 R 1 -XIII: A 3- to 7-membered ring formed by combining R 1 and R 2 is aziridine, azetidine, pyrrolidine, oxazolidine, thiazolidine, piperidine, morpholine, thiomorpholine and homopiperidine.

R1-XIV：C1〜C6アルキル、-OR26によって任意に置換されたC1〜C4アルキル［ここで、R26はC1〜C4アルキル、C1〜C4アルキルアミノカルボニル又はジ(C1〜C4アルキル)アミノカルボニルを表す。］、C1〜C4アルキルチオ(C1〜C4)アルキル、C1〜C4アルキルスルフィニル(C1〜C4)アルキル及びC1〜C4アルキルスルホニル(C1〜C4)アルキル、-N(R27)R26によって任意に置換された(C1〜C4)アルキル［ここで、R26はC1〜C4アルコキシカルボニル、C1〜C4アルキルスルホニル又はジ(C1〜C4アルキル)チオホスホリルを表し、R27は水素原子又はC1〜C4アルキルを表す。］及び-CH=NOH又は-CH=NOR31によって任意に置換されたC1〜C4アルキル［ここで、R31はC1〜C4アルキルを表す。］。 R 1 -XIV: C 1 -C 6 alkyl, C 1 -C 4 alkyl optionally substituted by —OR 26 [where R 26 is C 1 -C 4 alkyl, C 1 -C 4 alkylaminocarbonyl or Represents di (C 1 -C 4 alkyl) aminocarbonyl. ], C 1 -C 4 alkylthio (C 1 ~C 4) alkyl, C 1 -C 4 alkylsulfinyl (C 1 ~C 4) alkyl and C 1 -C 4 alkylsulfonyl (C 1 ~C 4) alkyl, - (C 1 -C 4 ) alkyl optionally substituted by N (R 27 ) R 26 , wherein R 26 is C 1 -C 4 alkoxycarbonyl, C 1 -C 4 alkylsulfonyl or di (C 1 -C 4 alkyl) thiophosphoryl, R 27 represents a hydrogen atom or C 1 -C 4 alkyl. And C 1 -C 4 alkyl optionally substituted by —CH═NOH or —CH═NOR 31 , wherein R 31 represents C 1 -C 4 alkyl. ].

本発明に包含される化合物において、R2及びR3で表される置換基の範囲として、例えば下記の各群が挙げられる。 In the compounds included in the present invention, examples of the range of substituents represented by R 2 and R 3 include the following groups.

すなわち、R2-I又はR3-I：水素原子。 That is, R 2 -I or R 3 -I: a hydrogen atom.

R2-II又はR3-II：水素原子及びC1〜C6アルキル。 R 2 -II or R 3 -II: hydrogen atom and C 1 -C 6 alkyl.

R2-III又はR3-III：水素原子、C1〜C4アルコキシ(C1〜C4)アルキル、C1〜C4アルキルチオ(C1〜C4)アルキル及びC1〜C4アルキルスルホニル(C1〜C4)アルキル。 R 2 -III or R 3 -III: hydrogen atom, C 1 -C 4 alkoxy (C 1 ~C 4) alkyl, C 1 -C 4 alkylthio (C 1 ~C 4) alkyl and C 1 -C 4 alkylsulfonyl (C 1 ~C 4) alkyl.

R2-IV又はR3-IV：水素原子、C3〜C6アルケニル及びC3〜C6アルキニル。 R 2 -IV or R 3 -IV: a hydrogen atom, C 3 -C 6 alkenyl and C 3 -C 6 alkynyl.

R2-V又はR3-V：水素原子、C1〜C6アルキルチオ、C1〜C6ハロアルキルチオ、フェニルチオ、(Z)p1によって置換されたフェニルチオ及び-SN(R18)R17［ここで、R17はC1〜C6アルキル、C1〜C6アルコキシカルボニル(C1〜C4)アルキル又はC1〜C6アルコキシカルボニルを表し、R18はC1〜C6アルキルを表すか、或いは、R17とR18とが一緒になってC4〜C5アルキレン鎖を形成することにより、結合する窒素原子と共に５員環又は６員環を形成してもよいことを表し、このときこのアルキレン鎖は酸素原子又は硫黄原子１個を含んでもよく、且つメチル基又はメトキシ基によって任意に置換されていてもよいことを表す。］。 R 2 -V or R 3 -V: hydrogen atom, C 1 -C 6 alkylthio, C 1 -C 6 haloalkylthio, phenylthio, (Z) phenylthio and -SN substituted by p1 (R 18) R 17 [wherein R 17 represents C 1 -C 6 alkyl, C 1 -C 6 alkoxycarbonyl (C 1 -C 4 ) alkyl or C 1 -C 6 alkoxycarbonyl, and R 18 represents C 1 -C 6 alkyl Or R 17 and R 18 together form a C 4 to C 5 alkylene chain to form a 5- or 6-membered ring with the nitrogen atom to which it is bound, Sometimes this alkylene chain may contain one oxygen or sulfur atom and may be optionally substituted with a methyl or methoxy group. ].

本発明に包含される化合物において、R4で表される置換基の範囲として、例えば下記の各群が挙げられる。 In the compound included in the present invention, examples of the range of the substituent represented by R 4 include the following groups.

すなわち、R4-I：C1〜C6アルキル及びC1〜C6ハロアルキル。 That is, R 4 -I: C 1 -C 6 alkyl and C 1 -C 6 haloalkyl.

R4-II：C1〜C6アルキル、C1〜C6ハロアルキル、C3〜C8シクロアルキル及びC3〜C8ハロシクロアルキル。 R 4 -II: C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, C 3 -C 8 cycloalkyl and C 3 -C 8 halocycloalkyl.

R4-III：R21によって任意に置換された(C1〜C6)アルキル及びR21によって任意に置換された(C1〜C6)ハロアルキル［ここで、R21はシアノ、C3〜C6シクロアルキル、C3〜C6ハロシクロアルキル、C1〜C6アルコキシ、C1〜C6ハロアルコキシ、フェノキシ、(Z)p1によって置換されたフェノキシ、C1〜C6アルキルチオ、C1〜C6ハロアルキルチオ、フェニルチオ、(Z)p1によって置換されたフェニルチオ、C1〜C6アルキルスルフィニル、C1〜C6ハロアルキルスルフィニル、C1〜C6アルキルスルホニル、C1〜C6ハロアルキルスルホニル、フェニルスルホニル、(Z)p1によって置換されたフェニルスルホニル、C1〜C6アルキルアミノ、ジ(C1〜C6アルキル)アミノ、フェニルアミノ、(Z)p1によって置換されたフェニルアミノ、C1〜C6アルコキシカルボニル、フェニル、(Z)p1によって置換されたフェニル、L-1〜L-5、L-8〜L-24、L-36、L-39、L-45〜L-52又はL-53を表す。］。 R 4 -III: optionally substituted by R 21 (C 1 ~C 6) optionally substituted by alkyl and R 21 (C 1 ~C 6) haloalkyl [wherein, R 21 is cyano, C 3 ~ C 6 cycloalkyl, C 3 -C 6 halocycloalkyl, C 1 -C 6 alkoxy, C 1 -C 6 haloalkoxy, phenoxy, (Z) p1 phenoxy substituted by, C 1 -C 6 alkylthio, C 1 -C 6 haloalkylthio, phenylthio, (Z) phenylthio substituted by p1, C 1 -C 6 alkylsulfinyl, C 1 -C 6 haloalkylsulfinyl, C 1 -C 6 alkylsulfonyl, C 1 -C 6 haloalkylsulfonyl, phenylsulfonyl, (Z) phenylsulfonyl substituted by p1, C 1 -C 6 alkylamino, di (C 1 -C 6 alkyl) amino, phenylamino, (Z) phenylamino substituted by p1, C 1 ~ C 6 alkoxycarbonyl , Phenyl, (Z) phenyl substituted by p1 , L-1 to L-5, L-8 to L-24, L-36, L-39, L-45 to L-52 or L-53 . ].

R4-IV：C3〜C6ハロアルケニル、C3〜C6ハロアルキニル、フェニル及び(Z)p1によって置換されたフェニル。 R 4 -IV: C 3 -C 6 haloalkenyl, C 3 -C 6 haloalkynyl, phenyl and phenyl substituted by (Z) p1 .

本発明に包含される化合物において、R5で表される置換基の範囲として、例えば下記の各群が挙げられる。 In the compounds included in the present invention, examples of the range of the substituent represented by R 5 include the following groups.

すなわち、R5-I：R21によって任意に置換された(C1〜C6)アルキル、R21によって任意に置換された(C1〜C6)ハロアルキル、R21によって任意に置換された(C2〜C6)アルケニル及びR21によって任意に置換された(C2〜C6)アルキニル［ここで、R21はC1〜C6アルコキシ、C1〜C6ハロアルコキシ、フェノキシ、(Z)p1によって置換されたフェノキシ、フェニルチオ、(Z)p1によって置換されたフェニルチオ、フェニルスルホニル、(Z)p1によって置換されたフェニルスルホニル、C1〜C6アルキルアミノ、ジ(C1〜C6アルキル)アミノ、フェニルアミノ、(Z)p1によって置換されたフェニルアミノ、C1〜C6アルコキシカルボニル、フェニル、(Z)p1によって置換されたフェニル、L-1〜L-5、L-8〜L-24、L-36、L-39、L-45〜L-52又はL-53を表す。］。 That, R 5 -I: (C 1 ~C 6) alkyl, optionally substituted by R 21 optionally substituted by R 21 (C 1 ~C 6) haloalkyl, optionally substituted by R 21 ( optionally substituted by C 2 -C 6) alkenyl and R 21 (C 2 ~C 6) alkynyl [where, R 21 is C 1 -C 6 alkoxy, C 1 -C 6 haloalkoxy, phenoxy, (Z ) p1 phenoxy substituted by, phenylthio, phenylthio substituted by (Z) p1, phenylsulfonyl, (Z) phenylsulfonyl substituted by p1, C 1 -C 6 alkylamino, di (C 1 -C 6 alkyl ) amino, phenylamino, (Z) phenylamino substituted by p1, C 1 -C 6 alkoxycarbonyl, phenyl, phenyl substituted by (Z) p1, L-1~L -5, L-8~L -24, L-36, L-39, L-45 to L-52 or L-53. ].

R5-II：R21によって任意に置換された(C1〜C6)アルキル、R21によって任意に置換された(C1〜C6)ハロアルキル、R21によって任意に置換された(C2〜C6)アルケニル及びR21によって任意に置換された(C2〜C6)アルキニル［ここで、R21はシアノ、C3〜C6シクロアルキル、C3〜C6ハロシクロアルキル、C1〜C6アルコキシ、C1〜C6ハロアルコキシ、フェノキシ、(Z)p1によって置換されたフェノキシ、C1〜C6アルキルチオ、C1〜C6ハロアルキルチオ、フェニルチオ、(Z)p1によって置換されたフェニルチオ、C1〜C6アルキルスルフィニル、C1〜C6ハロアルキルスルフィニル、C1〜C6アルキルスルホニル、C1〜C6ハロアルキルスルホニル、フェニルスルホニル、(Z)p1によって置換されたフェニルスルホニル、C1〜C6アルキルアミノ、ジ(C1〜C6アルキル)アミノ、フェニルアミノ、(Z)p1によって置換されたフェニルアミノ、C1〜C6アルコキシカルボニル、フェニル、(Z)p1によって置換されたフェニル、L-1〜L-5、L-8〜L-24、L-36、L-39、L-45〜L-52又はL-53を表す。］。 R 5 -II: optionally substituted by R 21 (C 1 ~C 6) alkyl, optionally substituted by optionally substituted by R 21 (C 1 ~C 6) haloalkyl, R 21 (C 2 -C 6) optionally substituted by alkenyl and R 21 (C 2 ~C 6) alkynyl [where, R 21 is cyano, C 3 -C 6 cycloalkyl, C 3 -C 6 halocycloalkyl, C 1 -C 6 alkoxy, C 1 -C 6 haloalkoxy, phenoxy, substituted by (Z) p1 phenoxy substituted by, C 1 -C 6 alkylthio, C 1 -C 6 haloalkylthio, phenylthio, (Z) p1 phenylthio, C 1 -C 6 alkylsulfinyl, C 1 -C 6 haloalkylsulfinyl, C 1 -C 6 alkylsulfonyl, C 1 -C 6 haloalkylsulfonyl, phenylsulfonyl, phenylsulfonyl substituted by (Z) p1, C 1 -C 6 alkylamino, di (C 1 -C 6 A Kill) amino, phenylamino, (Z) phenylamino substituted by p1, C 1 -C 6 alkoxycarbonyl, phenyl, (Z) phenyl substituted by p1, L-1~L-5, L-8~ L-24, L-36, L-39, L-45 to L-52 or L-53 is represented. ].

R5-III：フェニル、(Z)p1によって置換されたフェニル、(Z)p1によって置換されたフェノキシフェニル、(Z)p1によって置換されたピリジルオキシフェニル、L-1〜L-4、L-8〜L-13、L-15〜L-23、L-45〜L-52及びL-53。 R 5 -III: phenyl, (Z) phenyl substituted by p1, (Z) phenoxyphenyl phenyl substituted by p1, (Z) pyridyloxy phenyl substituted by p1, L-1~L-4, L- 8 to L-13, L-15 to L-23, L-45 to L-52 and L-53.

R5-IV：C3〜C8シクロアルキル、C3〜C8ハロシクロアルキル、フェニル、(Z)p1によって置換されたフェニル、(Z)p1によって置換されたフェノキシフェニル、(Z)p1によって置換されたピリジルオキシフェニル、L-1〜L-4、L-8〜L-13、L-15〜L-23、L-25〜L-35、L-37、L-38、L-40、L-43〜L-58、M-4、M-5、M-8、M-9、M-14〜M-18及びM-19。 R 5 -IV: C 3 ~C 8 cycloalkyl, C 3 -C 8 halocycloalkyl, phenyl, (Z) phenyl substituted by p1, phenoxyphenyl substituted by (Z) p1, by (Z) p1 Substituted pyridyloxyphenyl, L-1 to L-4, L-8 to L-13, L-15 to L-23, L-25 to L-35, L-37, L-38, L-40 , L-43 to L-58, M-4, M-5, M-8, M-9, M-14 to M-18 and M-19.

R5-V：シアノ、-C(O)OR9、-C(O)SR9、-C(O)NHR10、-C(O)N(R10)R9、-C(S)OR9、-C(S)SR9、-C(S)NHR10及び-C(S)N(R10)R9［ここで、R9はC1〜C6アルキル、C1〜C6ハロアルキル、C3〜C6シクロアルキル(C1〜C4)アルキル、フェニル(C1〜C4)アルキル、(Z)p1によって置換されたフェニル(C1〜C4)アルキル、C3〜C8シクロアルキル、C3〜C8ハロシクロアルキル、フェニル又は(Z)p1によって置換されたフェニルを表し、R10は水素原子又はC1〜C6アルキルを表すか、或いは、R9とR10とが一緒になってC4〜C5アルキレン鎖を形成することにより、結合する窒素原子と共に５員環又は６員環を形成してもよいことを表し、このときこのアルキレン鎖は酸素原子又は硫黄原子を１個含んでもよいことを表す。］。 R 5 -V: cyano, -C (O) OR 9 , -C (O) SR 9 , -C (O) NHR 10 , -C (O) N (R 10 ) R 9 , -C (S) OR 9 , -C (S) SR 9 , -C (S) NHR 10 and -C (S) N (R 10 ) R 9 [where R 9 is C 1 -C 6 alkyl, C 1 -C 6 haloalkyl , C 3 -C 6 cycloalkyl (C 1 ~C 4) alkyl, phenyl (C 1 ~C 4) alkyl, phenyl (C 1 ~C 4) substituted by (Z) p1 alkyl, C 3 -C 8 cycloalkyl, C 3 -C 8 halocycloalkyl, phenyl which is substituted by phenyl or (Z) p1, or R 10 represents a hydrogen atom or a C 1 -C 6 alkyl, or the R 9 and R 10 Together form a C 4 to C 5 alkylene chain to form a 5-membered or 6-membered ring with the nitrogen atom to which the alkylene chain is bonded. Indicates that one atom may be included. ].

R5-VI：隣接位に存在するYと一緒になってC2〜C3アルキレン鎖を形成することにより、ベンゼン環と縮合する５〜６員環を形成し、このときこのアルキレン鎖は酸素原子、硫黄原子又は窒素原子を１個含んでもよく、且つハロゲン原子又はC1〜C6ハロアルキル基によって任意に置換されていてもよい。 R 5 -VI: Forms a C 2 -C 3 alkylene chain together with Y present at the adjacent position, thereby forming a 5- to 6-membered ring condensed with the benzene ring. At this time, the alkylene chain is oxygen atoms, it may contain one sulfur atom or nitrogen atom may be optionally substituted and the halogen atom or a C 1 -C 6 haloalkyl group.

本発明に包含される化合物において、R6で表される置換基の範囲として、例えば下記の各群が挙げられる。 In the compounds included in the present invention, examples of the range of the substituent represented by R 6 include the following groups.

すなわち、R6-I：水素原子。 That is, R 6 -I: a hydrogen atom.

R6-II：水素原子、C1〜C6アルキル、C1〜C4アルコキシ(C1〜C4)アルキル、C1〜C6アルキルカルボニル及びトリ(C1〜C4アルキル)シリル。 R 6 -II: a hydrogen atom, C 1 -C 6 alkyl, C 1 -C 4 alkoxy (C 1 -C 4 ) alkyl, C 1 -C 6 alkylcarbonyl and tri (C 1 -C 4 alkyl) silyl.

R6-III：水素原子、C1〜C6アルキル、C1〜C6ハロアルキル、C1〜C4アルコキシ(C1〜C4)アルキル、C1〜C4アルキルチオ(C1〜C4)アルキル、シアノ(C1〜C6)アルキル、フェニル(C1〜C4)アルキル、(Z)p1によって置換されたフェニル(C1〜C4)アルキル、C3〜C6アルケニル、C3〜C6ハロアルケニル、フェニル(C3〜C6)アルケニル、(Z)p1によって置換されたフェニル(C3〜C6)アルケニル、C3〜C6アルキニル、C3〜C6ハロアルキニル、フェニル(C3〜C6)アルキニル、(Z)p1によって置換されたフェニル(C3〜C6)アルキニル、-S(O)2R9、-C(O)R9、-C(O)NHR10、-C(O)N(R10)R9、-C(S)NHR10、-C(S)N(R10)R9［ここで、R9はC1〜C6アルキル、C1〜C6ハロアルキル、C3〜C6シクロアルキル(C1〜C4)アルキル、フェニル(C1〜C4)アルキル、(Z)p1によって置換されたフェニル(C1〜C4)アルキル、C3〜C8シクロアルキル、C3〜C8ハロシクロアルキル、フェニル又は(Z)p1によって置換されたフェニルを表し、R10は水素原子又はC1〜C6アルキルを表すか、或いは、R9とR10とが一緒になってC4〜C5アルキレン鎖を形成することにより、結合する窒素原子と共に５員環又は６員環を形成してもよいことを表し、このときこのアルキレン鎖は酸素原子又は硫黄原子を１個含んでもよいことを表す。］、-Si(R13)(R14)R12［ここで、R12はC1〜C6アルキル、フェニル又は(Z)p1によって置換されたフェニルを表し、R13及びR14は各々独立してC1〜C6アルキルを表す。］、-P(O)(OR22)2及び-P(S)(OR22)2［ここで、R22はC1〜C6アルキルを表す。］。 R 6 -III: hydrogen atom, C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, C 1 -C 4 alkoxy (C 1 -C 4 ) alkyl, C 1 -C 4 alkylthio (C 1 -C 4 ) alkyl, cyano (C 1 ~C 6) alkyl, phenyl (C 1 ~C 4) alkyl, (Z) phenyl substituted by p1 (C 1 ~C 4) alkyl, C 3 -C 6 alkenyl, C 3 ~ C 6 haloalkenyl, phenyl (C 3 -C 6) alkenyl, (Z) phenyl substituted by p1 (C 3 ~C 6) alkenyl, C 3 -C 6 alkynyl, C 3 -C 6 haloalkynyl, phenyl ( C 3 -C 6) alkynyl, (Z) phenyl substituted by p1 (C 3 ~C 6) alkynyl, -S (O) 2 R 9 , -C (O) R 9, -C (O) NHR 10 , -C (O) N (R 10 ) R 9 , -C (S) NHR 10 , -C (S) N (R 10 ) R 9 [where R 9 is C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, C 3 -C 6 cycloalkyl (C 1 ~C 4) alkyl, phenyl (C 1 ~C 4) alkyl, it is substituted by (Z) p1 Represents phenyl (C 1 -C 4 ) alkyl, C 3 -C 8 cycloalkyl, C 3 -C 8 halocycloalkyl, phenyl or phenyl substituted by (Z) p1 , and R 10 represents a hydrogen atom or C Represents 1 to C 6 alkyl, or R 9 and R 10 together form a C 4 to C 5 alkylene chain to form a 5- or 6-membered ring with the nitrogen atom to which it is attached. In this case, this alkylene chain may contain one oxygen atom or one sulfur atom. ], -Si (R 13 ) (R 14 ) R 12 [wherein R 12 represents C 1 -C 6 alkyl, phenyl or phenyl substituted by (Z) p 1 , and R 13 and R 14 are each independently and it represents a C 1 -C 6 alkyl. ], -P (O) (OR 22 ) 2 and -P (S) (OR 22 ) 2 [wherein R 22 represents C 1 -C 6 alkyl. ].

これらの本発明に包含される化合物における各置換基の範囲を示す各群は、それぞれ任意に組み合わせることができそれぞれ本発明化合物の範囲を表す。R1、R4、R5及びR6についての範囲の組み合わせの例としては、例えば以下の第１表に示す組み合わせが挙げられる。但し、第１表の組み合わせは例示のためのものであって、本発明はこれらのみに限定されるものではない。
第１表 第１表（続き）
―――――――――――――――――― ――――――――――――――――――
R1 R4 R5 R6 R1 R4 R5 R6
―――――――――――――――――― ――――――――――――――――――
R1-I R4-I R5-I R6-I R1-VIII R4-I R5-I R6-I
R1-I R4-I R5-I R6-II R1-VIII R4-I R5-I R6-II
R1-I R4-I R5-III R6-I R1-VIII R4-I R5-III R6-I
R1-I R4-I R5-III R6-II R1-VIII R4-I R5-III R6-II
R1-I R4-I R5-VI R6-I R1-VIII R4-I R5-VI R6-I
R1-I R4-I R5-VI R6-II R1-VIII R4-I R5-VI R6-II
R1-II R4-I R5-I R6-I R1-IX R4-I R5-I R6-I
R1-II R4-I R5-I R6-II R1-IX R4-I R5-I R6-II
R1-II R4-I R5-III R6-I R1-IX R4-I R5-III R6-I
R1-II R4-I R5-III R6-II R1-IX R4-I R5-III R6-II
R1-II R4-I R5-III R6-III R1-IX R4-I R5-III R6-III
R1-II R4-I R5-IV R6-I R1-IX R4-I R5-IV R6-I
R1-II R4-I R5-IV R6-II R1-IX R4-I R5-IV R6-II
R1-II R4-I R5-V R6-I R1-IX R4-I R5-V R6-I
R1-II R4-I R5-V R6-II R1-IX R4-I R5-V R6-II
R1-II R4-I R5-VI R6-I R1-IX R4-I R5-VI R6-I
R1-II R4-I R5-VI R6-II R1-IX R4-I R5-VI R6-II
R1-II R4-II R5-I R6-I R1-IX R4-II R5-I R6-I
R1-II R4-II R5-I R6-II R1-IX R4-II R5-I R6-II
R1-II R4-II R5-III R6-I R1-IX R4-II R5-III R6-I
R1-II R4-II R5-III R6-II R1-IX R4-II R5-III R6-II
R1-II R4-II R5-III R6-III R1-IX R4-II R5-III R6-III
R1-II R4-II R5-IV R6-I R1-IX R4-II R5-IV R6-I
R1-II R4-II R5-IV R6-II R1-IX R4-II R5-IV R6-II
R1-II R4-II R5-V R6-I R1-IX R4-II R5-V R6-I
R1-II R4-II R5-V R6-II R1-IX R4-II R5-V R6-II
R1-II R4-II R5-VI R6-I R1-IX R4-II R5-VI R6-I
R1-II R4-II R5-VI R6-II R1-IX R4-II R5-VI R6-II
R1-II R4-III R5-III R6-I R1-IX R4-III R5-III R6-I
R1-II R4-III R5-III R6-II R1-IX R4-III R5-III R6-II
R1-II R4-IV R5-III R6-I R1-IX R4-IV R5-III R6-I
R1-III R4-I R5-I R6-I R1-X R4-I R5-I R6-I
R1-III R4-I R5-I R6-II R1-X R4-I R5-I R6-II
R1-III R4-I R5-III R6-I R1-X R4-I R5-III R6-I
R1-III R4-I R5-III R6-II R1-X R4-I R5-III R6-II
R1-III R4-I R5-III R6-III R1-X R4-I R5-III R6-III
R1-III R4-I R5-IV R6-I R1-X R4-I R5-IV R6-I
R1-III R4-I R5-IV R6-II R1-X R4-I R5-IV R6-II
R1-III R4-I R5-V R6-I R1-X R4-I R5-V R6-I
R1-III R4-I R5-V R6-II R1-X R4-I R5-V R6-II
R1-III R4-I R5-VI R6-I R1-X R4-I R5-VI R6-I
R1-III R4-I R5-VI R6-II R1-X R4-I R5-VI R6-II
R1-III R4-II R5-I R6-I R1-X R4-II R5-I R6-I
R1-III R4-II R5-I R6-II R1-X R4-II R5-I R6-II
R1-III R4-II R5-III R6-I R1-X R4-II R5-III R6-I
R1-III R4-II R5-III R6-II R1-X R4-II R5-III R6-II
R1-III R4-II R5-III R6-III R1-X R4-II R5-III R6-III
R1-III R4-II R5-IV R6-I R1-X R4-II R5-IV R6-I
R1-III R4-II R5-IV R6-II R1-X R4-II R5-IV R6-II
R1-III R4-II R5-V R6-I R1-X R4-II R5-V R6-I
R1-III R4-II R5-V R6-II R1-X R4-II R5-V R6-II
R1-III R4-II R5-VI R6-I R1-X R4-II R5-VI R6-I
R1-III R4-II R5-VI R6-II R1-X R4-II R5-VI R6-II
R1-III R4-III R5-III R6-I R1-X R4-III R5-III R6-I
R1-III R4-III R5-III R6-II R1-X R4-III R5-III R6-II
R1-III R4-IV R5-III R6-I R1-X R4-IV R5-III R6-I
R1-IV R4-I R5-I R6-I R1-XI R4-I R5-I R6-I
R1-IV R4-I R5-III R6-I R1-XI R4-I R5-III R6-I
R1-IV R4-I R5-III R6-II R1-XI R4-I R5-III R6-II
R1-IV R4-I R5-VI R6-I R1-XI R4-I R5-VI R6-I
R1-V R4-I R5-I R6-I R1-XII R4-I R5-I R6-I
R1-V R4-I R5-III R6-I R1-XII R4-I R5-III R6-I
R1-V R4-I R5-III R6-II R1-XII R4-I R5-III R6-II
R1-V R4-I R5-VI R6-I R1-XII R4-I R5-VI R6-I
R1-VI R4-I R5-I R6-I R1-XIII R4-I R5-I R6-I
R1-VI R4-I R5-III R6-I R1-XIII R4-I R5-III R6-I
R1-VI R4-I R5-III R6-II R1-XIII R4-I R5-III R6-II
R1-VI R4-I R5-VI R6-I R1-XIII R4-I R5-VI R6-I
R1-VII R4-I R5-I R6-I R1-XIV R4-I R5-I R6-I
R1-VII R4-I R5-I R6-II R1-XIV R4-I R5-I R6-II
R1-VII R4-I R5-I R6-III R1-XIV R4-I R5-I R6-III
R1-VII R4-I R5-II R6-I R1-XIV R4-I R5-II R6-I
R1-VII R4-I R5-II R6-II R1-XIV R4-I R5-II R6-II
R1-VII R4-I R5-III R6-I R1-XIV R4-I R5-III R6-I
R1-VII R4-I R5-III R6-II R1-XIV R4-I R5-III R6-II
R1-VII R4-I R5-III R6-III R1-XIV R4-I R5-III R6-III
R1-VII R4-I R5-IV R6-I R1-XIV R4-I R5-IV R6-I
R1-VII R4-I R5-IV R6-II R1-XIV R4-I R5-IV R6-II
R1-VII R4-I R5-IV R6-III R1-XIV R4-I R5-IV R6-III
R1-VII R4-I R5-V R6-I R1-XIV R4-I R5-V R6-I
R1-VII R4-I R5-V R6-II R1-XIV R4-I R5-V R6-II
R1-VII R4-I R5-VI R6-I R1-XIV R4-I R5-VI R6-I
R1-VII R4-I R5-VI R6-II R1-XIV R4-I R5-VI R6-II
R1-VII R4-I R5-VI R6-III R1-XIV R4-I R5-VI R6-III
R1-VII R4-II R5-I R6-I R1-XIV R4-II R5-I R6-I
R1-VII R4-II R5-I R6-II R1-XIV R4-II R5-I R6-II
R1-VII R4-II R5-II R6-I R1-XIV R4-II R5-II R6-I
R1-VII R4-II R5-III R6-I R1-XIV R4-II R5-III R6-I
R1-VII R4-II R5-III R6-II R1-XIV R4-II R5-III R6-II
R1-VII R4-II R5-IV R6-I R1-XIV R4-II R5-IV R6-I
R1-VII R4-II R5-IV R6-II R1-XIV R4-II R5-IV R6-II
R1-VII R4-II R5-V R6-I R1-XIV R4-II R5-V R6-I
R1-VII R4-II R5-VI R6-I R1-XIV R4-II R5-VI R6-I
R1-VII R4-II R5-VI R6-II R1-XIV R4-II R5-VI R6-II
R1-VII R4-III R5-I R6-I R1-XIV R4-III R5-I R6-I
R1-VII R4-III R5-I R6-II R1-XIV R4-III R5-I R6-II
R1-VII R4-III R5-III R6-I R1-XIV R4-III R5-III R6-I
R1-VII R4-III R5-III R6-II R1-XIV R4-III R5-III R6-II
R1-VII R4-III R5-IV R6-I R1-XIV R4-III R5-IV R6-I
R1-VII R4-III R5-V R6-I R1-XIV R4-III R5-V R6-I
R1-VII R4-III R5-VI R6-I R1-XIV R4-III R5-VI R6-I
R1-VII R4-IV R5-I R6-I R1-XIV R4-IV R5-I R6-I
R1-VII R4-IV R5-I R6-II R1-XIV R4-IV R5-I R6-II
R1-VII R4-IV R5-III R6-I R1-XIV R4-IV R5-III R6-I
R1-VII R4-IV R5-III R6-II R1-XIV R4-IV R5-III R6-II
R1-VII R4-IV R5-IV R6-I R1-XIV R4-IV R5-IV R6-I
R1-VII R4-IV R5-V R6-I R1-XIV R4-IV R5-V R6-I
R1-VII R4-IV R5-VI R6-I R1-XIV R4-IV R5-VI R6-I
―――――――――――――――――― ――――――――――――――――――
本発明化合物は、例えば以下の方法により製造することが出来る。 Each group which shows the range of each substituent in these compounds included in the present invention can be arbitrarily combined, and each represents the range of the present compound. Examples of combinations of ranges for R 1 , R 4 , R 5 and R 6 include the combinations shown in Table 1 below. However, the combinations in Table 1 are for illustrative purposes, and the present invention is not limited to these.
Table 1 Table 1 (continued)
―――――――――――――――――― ――――――――――――――――――
R 1 R 4 R 5 R 6 R 1 R 4 R 5 R 6
―――――――――――――――――― ――――――――――――――――――
R 1 -IR 4 -IR 5 -IR 6 -IR 1 -VIII R 4 -IR 5 -IR 6 -I
R 1 -IR 4 -IR 5 -IR 6 -II R 1 -VIII R 4 -IR 5 -IR 6 -II
R 1 -IR 4 -IR 5 -III R 6 -IR 1 -VIII R 4 -IR 5 -III R 6 -I
R 1 -IR 4 -IR 5 -III R 6 -II R 1 -VIII R 4 -IR 5 -III R 6 -II
R 1 -IR 4 -IR 5 -VI R 6 -IR 1 -VIII R 4 -IR 5 -VI R 6 -I
R 1 -IR 4 -IR 5 -VI R 6 -II R 1 -VIII R 4 -IR 5 -VI R 6 -II
R 1 -II R 4 -IR 5 -IR 6 -IR 1 -IX R 4 -IR 5 -IR 6 -I
R 1 -II R 4 -IR 5 -IR 6 -II R 1 -IX R 4 -IR 5 -IR 6 -II
R 1 -II R 4 -IR 5 -III R 6 -IR 1 -IX R 4 -IR 5 -III R 6 -I
R 1 -II R 4 -IR 5 -III R 6 -II R 1 -IX R 4 -IR 5 -III R 6 -II
R 1 -II R 4 -IR 5 -III R 6 -III R 1 -IX R 4 -IR 5 -III R 6 -III
R 1 -II R 4 -IR 5 -IV R 6 -IR 1 -IX R 4 -IR 5 -IV R 6 -I
R 1 -II R 4 -IR 5 -IV R 6 -II R 1 -IX R 4 -IR 5 -IV R 6 -II
R 1 -II R 4 -IR 5 -VR 6 -IR 1 -IX R 4 -IR 5 -VR 6 -I
R 1 -II R 4 -IR 5 -VR 6 -II R 1 -IX R 4 -IR 5 -VR 6 -II
R 1 -II R 4 -IR 5 -VI R 6 -IR 1 -IX R 4 -IR 5 -VI R 6 -I
R 1 -II R 4 -IR 5 -VI R 6 -II R 1 -IX R 4 -IR 5 -VI R 6 -II
R 1 -II R 4 -II R 5 -IR 6 -IR 1 -IX R 4 -II R 5 -IR 6 -I
R 1 -II R 4 -II R 5 -IR 6 -II R 1 -IX R 4 -II R 5 -IR 6 -II
R 1 -II R 4 -II R 5 -III R 6 -IR 1 -IX R 4 -II R 5 -III R 6 -I
R 1 -II R 4 -II R 5 -III R 6 -II R 1 -IX R 4 -II R 5 -III R 6 -II
R 1 -II R 4 -II R 5 -III R 6 -III R 1 -IX R 4 -II R 5 -III R 6 -III
R 1 -II R 4 -II R 5 -IV R 6 -IR 1 -IX R 4 -II R 5 -IV R 6 -I
R 1 -II R 4 -II R 5 -IV R 6 -II R 1 -IX R 4 -II R 5 -IV R 6 -II
R 1 -II R 4 -II R 5 -VR 6 -IR 1 -IX R 4 -II R 5 -VR 6 -I
R 1 -II R 4 -II R 5 -VR 6 -II R 1 -IX R 4 -II R 5 -VR 6 -II
R 1 -II R 4 -II R 5 -VI R 6 -IR 1 -IX R 4 -II R 5 -VI R 6 -I
R 1 -II R 4 -II R 5 -VI R 6 -II R 1 -IX R 4 -II R 5 -VI R 6 -II
R 1 -II R 4 -III R 5 -III R 6 -IR 1 -IX R 4 -III R 5 -III R 6 -I
R 1 -II R 4 -III R 5 -III R 6 -II R 1 -IX R 4 -III R 5 -III R 6 -II
R 1 -II R 4 -IV R 5 -III R 6 -IR 1 -IX R 4 -IV R 5 -III R 6 -I
R 1 -III R 4 -IR 5 -IR 6 -IR 1 -XR 4 -IR 5 -IR 6 -I
R 1 -III R 4 -IR 5 -IR 6 -II R 1 -XR 4 -IR 5 -IR 6 -II
R 1 -III R 4 -IR 5 -III R 6 -IR 1 -XR 4 -IR 5 -III R 6 -I
R 1 -III R 4 -IR 5 -III R 6 -II R 1 -XR 4 -IR 5 -III R 6 -II
R 1 -III R 4 -IR 5 -III R 6 -III R 1 -XR 4 -IR 5 -III R 6 -III
R 1 -III R 4 -IR 5 -IV R 6 -IR 1 -XR 4 -IR 5 -IV R 6 -I
R 1 -III R 4 -IR 5 -IV R 6 -II R 1 -XR 4 -IR 5 -IV R 6 -II
R 1 -III R 4 -IR 5 -VR 6 -IR 1 -XR 4 -IR 5 -VR 6 -I
R 1 -III R 4 -IR 5 -VR 6 -II R 1 -XR 4 -IR 5 -VR 6 -II
R 1 -III R 4 -IR 5 -VI R 6 -IR 1 -XR 4 -IR 5 -VI R 6 -I
R 1 -III R 4 -IR 5 -VI R 6 -II R 1 -XR 4 -IR 5 -VI R 6 -II
R 1 -III R 4 -II R 5 -IR 6 -IR 1 -XR 4 -II R 5 -IR 6 -I
R 1 -III R 4 -II R 5 -IR 6 -II R 1 -XR 4 -II R 5 -IR 6 -II
R 1 -III R 4 -II R 5 -III R 6 -IR 1 -XR 4 -II R 5 -III R 6 -I
R 1 -III R 4 -II R 5 -III R 6 -II R 1 -XR 4 -II R 5 -III R 6 -II
R 1 -III R 4 -II R 5 -III R 6 -III R 1 -XR 4 -II R 5 -III R 6 -III
R 1 -III R 4 -II R 5 -IV R 6 -IR 1 -XR 4 -II R 5 -IV R 6 -I
R 1 -III R 4 -II R 5 -IV R 6 -II R 1 -XR 4 -II R 5 -IV R 6 -II
R 1 -III R 4 -II R 5 -VR 6 -IR 1 -XR 4 -II R 5 -VR 6 -I
R 1 -III R 4 -II R 5 -VR 6 -II R 1 -XR 4 -II R 5 -VR 6 -II
R 1 -III R 4 -II R 5 -VI R 6 -IR 1 -XR 4 -II R 5 -VI R 6 -I
R 1 -III R 4 -II R 5 -VI R 6 -II R 1 -XR 4 -II R 5 -VI R 6 -II
R 1 -III R 4 -III R 5 -III R 6 -IR 1 -XR 4 -III R 5 -III R 6 -I
R 1 -III R 4 -III R 5 -III R 6 -II R 1 -XR 4 -III R 5 -III R 6 -II
R 1 -III R 4 -IV R 5 -III R 6 -IR 1 -XR 4 -IV R 5 -III R 6 -I
R 1 -IV R 4 -IR 5 -IR 6 -IR 1 -XI R 4 -IR 5 -IR 6 -I
R 1 -IV R 4 -IR 5 -III R 6 -IR 1 -XI R 4 -IR 5 -III R 6 -I
R 1 -IV R 4 -IR 5 -III R 6 -II R 1 -XI R 4 -IR 5 -III R 6 -II
R 1 -IV R 4 -IR 5 -VI R 6 -IR 1 -XI R 4 -IR 5 -VI R 6 -I
R 1 -VR 4 -IR 5 -IR 6 -IR 1 -XII R 4 -IR 5 -IR 6 -I
R 1 -VR 4 -IR 5 -III R 6 -IR 1 -XII R 4 -IR 5 -III R 6 -I
R 1 -VR 4 -IR 5 -III R 6 -II R 1 -XII R 4 -IR 5 -III R 6 -II
R 1 -VR 4 -IR 5 -VI R 6 -IR 1 -XII R 4 -IR 5 -VI R 6 -I
R 1 -VI R 4 -IR 5 -IR 6 -IR 1 -XIII R 4 -IR 5 -IR 6 -I
R 1 -VI R 4 -IR 5 -III R 6 -IR 1 -XIII R 4 -IR 5 -III R 6 -I
R 1 -VI R 4 -IR 5 -III R 6 -II R 1 -XIII R 4 -IR 5 -III R 6 -II
R 1 -VI R 4 -IR 5 -VI R 6 -IR 1 -XIII R 4 -IR 5 -VI R 6 -I
R 1 -VII R 4 -IR 5 -IR 6 -IR 1 -XIV R 4 -IR 5 -IR 6 -I
R 1 -VII R 4 -IR 5 -IR 6 -II R 1 -XIV R 4 -IR 5 -IR 6 -II
R 1 -VII R 4 -IR 5 -IR 6 -III R 1 -XIV R 4 -IR 5 -IR 6 -III
R 1 -VII R 4 -IR 5 -II R 6 -IR 1 -XIV R 4 -IR 5 -II R 6 -I
R 1 -VII R 4 -IR 5 -II R 6 -II R 1 -XIV R 4 -IR 5 -II R 6 -II
R 1 -VII R 4 -IR 5 -III R 6 -IR 1 -XIV R 4 -IR 5 -III R 6 -I
R 1 -VII R 4 -IR 5 -III R 6 -II R 1 -XIV R 4 -IR 5 -III R 6 -II
R 1 -VII R 4 -IR 5 -III R 6 -III R 1 -XIV R 4 -IR 5 -III R 6 -III
R 1 -VII R 4 -IR 5 -IV R 6 -IR 1 -XIV R 4 -IR 5 -IV R 6 -I
R 1 -VII R 4 -IR 5 -IV R 6 -II R 1 -XIV R 4 -IR 5 -IV R 6 -II
R 1 -VII R 4 -IR 5 -IV R 6 -III R 1 -XIV R 4 -IR 5 -IV R 6 -III
R 1 -VII R 4 -IR 5 -VR 6 -IR 1 -XIV R 4 -IR 5 -VR 6 -I
R 1 -VII R 4 -IR 5 -VR 6 -II R 1 -XIV R 4 -IR 5 -VR 6 -II
R 1 -VII R 4 -IR 5 -VI R 6 -IR 1 -XIV R 4 -IR 5 -VI R 6 -I
R 1 -VII R 4 -IR 5 -VI R 6 -II R 1 -XIV R 4 -IR 5 -VI R 6 -II
R 1 -VII R 4 -IR 5 -VI R 6 -III R 1 -XIV R 4 -IR 5 -VI R 6 -III
R 1 -VII R 4 -II R 5 -IR 6 -IR 1 -XIV R 4 -II R 5 -IR 6 -I
R 1 -VII R 4 -II R 5 -IR 6 -II R 1 -XIV R 4 -II R 5 -IR 6 -II
R 1 -VII R 4 -II R 5 -II R 6 -IR 1 -XIV R 4 -II R 5 -II R 6 -I
R 1 -VII R 4 -II R 5 -III R 6 -IR 1 -XIV R 4 -II R 5 -III R 6 -I
R 1 -VII R 4 -II R 5 -III R 6 -II R 1 -XIV R 4 -II R 5 -III R 6 -II
R 1 -VII R 4 -II R 5 -IV R 6 -IR 1 -XIV R 4 -II R 5 -IV R 6 -I
R 1 -VII R 4 -II R 5 -IV R 6 -II R 1 -XIV R 4 -II R 5 -IV R 6 -II
R 1 -VII R 4 -II R 5 -VR 6 -IR 1 -XIV R 4 -II R 5 -VR 6 -I
R 1 -VII R 4 -II R 5 -VI R 6 -IR 1 -XIV R 4 -II R 5 -VI R 6 -I
R 1 -VII R 4 -II R 5 -VI R 6 -II R 1 -XIV R 4 -II R 5 -VI R 6 -II
R 1 -VII R 4 -III R 5 -IR 6 -IR 1 -XIV R 4 -III R 5 -IR 6 -I
R 1 -VII R 4 -III R 5 -IR 6 -II R 1 -XIV R 4 -III R 5 -IR 6 -II
R 1 -VII R 4 -III R 5 -III R 6 -IR 1 -XIV R 4 -III R 5 -III R 6 -I
R 1 -VII R 4 -III R 5 -III R 6 -II R 1 -XIV R 4 -III R 5 -III R 6 -II
R 1 -VII R 4 -III R 5 -IV R 6 -IR 1 -XIV R 4 -III R 5 -IV R 6 -I
R 1 -VII R 4 -III R 5 -VR 6 -IR 1 -XIV R 4 -III R 5 -VR 6 -I
R 1 -VII R 4 -III R 5 -VI R 6 -IR 1 -XIV R 4 -III R 5 -VI R 6 -I
R 1 -VII R 4 -IV R 5 -IR 6 -IR 1 -XIV R 4 -IV R 5 -IR 6 -I
R 1 -VII R 4 -IV R 5 -IR 6 -II R 1 -XIV R 4 -IV R 5 -IR 6 -II
R 1 -VII R 4 -IV R 5 -III R 6 -IR 1 -XIV R 4 -IV R 5 -III R 6 -I
R 1 -VII R 4 -IV R 5 -III R 6 -II R 1 -XIV R 4 -IV R 5 -III R 6 -II
R 1 -VII R 4 -IV R 5 -IV R 6 -IR 1 -XIV R 4 -IV R 5 -IV R 6 -I
R 1 -VII R 4 -IV R 5 -VR 6 -IR 1 -XIV R 4 -IV R 5 -VR 6 -I
R 1 -VII R 4 -IV R 5 -VI R 6 -IR 1 -XIV R 4 -IV R 5 -VI R 6 -I
―――――――――――――――――― ――――――――――――――――――
The compound of the present invention can be produced, for example, by the following method.

製造法A   Manufacturing method A

Figure 2005126418
Figure 2005126418

一般式(4)［式中、W1, W2, X, Y, R4, R5, R6, m及びnは前記と同じ意味を表す。］で表される化合物と一般式(5)［式中、R1及びR2は前記と同じ意味を表す。］で表される化合物とを、該反応に対して不活性な溶媒中又は無溶媒にて、必要ならば触媒の存在下、反応させることにより、一般式(1)においてR3が水素原子である一般式(1-1)［式中、W1, W2, X, Y, R1, R2, R4, R5, R6, m及びnは前記と同じ意味を表す。］で表される本発明化合物を得ることができる。 General formula (4) [wherein W 1 , W 2 , X, Y, R 4 , R 5 , R 6 , m and n represent the same meaning as described above. And a compound represented by the general formula (5): wherein R 1 and R 2 represent the same meaning as described above. In a solvent inert to the reaction or in the absence of a solvent, if necessary, in the presence of a catalyst, R 3 is a hydrogen atom in the general formula (1). A certain general formula (1-1) [wherein W 1 , W 2 , X, Y, R 1 , R 2 , R 4 , R 5 , R 6 , m and n represent the same meaning as described above. This invention compound represented by this can be obtained.

反応基質の量は、一般式(4)で表される化合物１当量に対して１〜５０当量の一般式(5)で表される化合物を用いることができる。   As the amount of the reaction substrate, 1 to 50 equivalents of the compound represented by the general formula (5) can be used per 1 equivalent of the compound represented by the general formula (4).

溶媒を用いる場合、用いられる溶媒としては反応の進行を阻害しないものであれば何でもよく、例えばベンゼン、トルエン、キシレン等の芳香族炭化水素類、ヘキサン、ヘプタン等の脂肪族炭化水素類、シクロヘキサン等の脂環式炭化水素類、クロロベンゼン、ジクロロベンゼン等の芳香族ハロゲン化炭化水素類、ジクロロメタン、クロロホルム、四塩化炭素、1,2-ジクロロエタン、1,1,1-トリクロロエタン、トリクロロエチレン、テトラクロロエチレン等の脂肪族ハロゲン化炭化水素類、ジエチルエーテル、1,2-ジメトキシエタン、テトラヒドロフラン、1,4-ジオキサン等のエーテル類、酢酸エチル、プロピオン酸エチル等のエステル類、ジメチルホルムアミド、ジメチルアセトアミド、Ｎ-メチル-2-ピロリドン等のアミド類、ギ酸、酢酸、プロピオン酸等のカルボン酸類、トリエチルアミン、トリブチルアミン、Ｎ,Ｎ-ジメチルアニリン等のアミン類、ピリジン、ピコリン等のピリジン類、メタノール、エタノール、エチレングリコール等のアルコール類、アセトニトリル、ジメチルスルホキシド、スルホラン、1,3-ジメチル-2-イミダゾリジノン及び水等が挙げられる。これらの溶媒は単独で用いても、これらのうちの２種類以上を混合して用いてもよい。   In the case of using a solvent, any solvent may be used as long as it does not inhibit the progress of the reaction. For example, aromatic hydrocarbons such as benzene, toluene and xylene, aliphatic hydrocarbons such as hexane and heptane, cyclohexane, etc. Alicyclic hydrocarbons, aromatic halogenated hydrocarbons such as chlorobenzene and dichlorobenzene, fats such as dichloromethane, chloroform, carbon tetrachloride, 1,2-dichloroethane, 1,1,1-trichloroethane, trichloroethylene and tetrachloroethylene Group halogenated hydrocarbons, ethers such as diethyl ether, 1,2-dimethoxyethane, tetrahydrofuran and 1,4-dioxane, esters such as ethyl acetate and ethyl propionate, dimethylformamide, dimethylacetamide, N-methyl- Amides such as 2-pyrrolidone, formic acid, acetic acid, propylene Carboxylic acids such as on acid, amines such as triethylamine, tributylamine, N, N-dimethylaniline, pyridines such as pyridine and picoline, alcohols such as methanol, ethanol and ethylene glycol, acetonitrile, dimethyl sulfoxide, sulfolane, 1 , 3-dimethyl-2-imidazolidinone and water. These solvents may be used alone or as a mixture of two or more thereof.

触媒を用いる場合、反応の触媒としては、例えば塩酸、硫酸、硝酸等の鉱酸類、ギ酸、酢酸、プロピオン酸、トリフルオロ酢酸、メタンスルホン酸、ベンゼンスルホン酸、p-トルエンスルホン酸等の有機酸類、トリエチルアミン塩酸塩、ピリジン塩酸塩等のアミン類の酸付加塩、塩化亜鉛、ヨウ化亜鉛、四塩化チタン、塩化セリウム、イッテルビウムトリフレート、三フッ化ホウ素-エーテル錯体等のルイス酸を、一般式(4)で表される化合物に対して０.００１〜１当量用いることができる。   When using a catalyst, examples of the reaction catalyst include mineral acids such as hydrochloric acid, sulfuric acid, and nitric acid, and organic acids such as formic acid, acetic acid, propionic acid, trifluoroacetic acid, methanesulfonic acid, benzenesulfonic acid, and p-toluenesulfonic acid. Acid addition salts of amines such as triethylamine hydrochloride, pyridine hydrochloride, Lewis acids such as zinc chloride, zinc iodide, titanium tetrachloride, cerium chloride, ytterbium triflate, boron trifluoride-ether complex, 0.001 to 1 equivalent can be used with respect to the compound represented by (4).

反応温度は−６０℃から反応混合物の還流温度までの任意の温度を設定することができ、反応時間は、反応基質の濃度、反応温度によって変化するが、通常５分から１００時間の範囲で任意に設定できる。   The reaction temperature can be set to an arbitrary temperature from −60 ° C. to the reflux temperature of the reaction mixture, and the reaction time varies depending on the concentration of the reaction substrate and the reaction temperature, but is usually arbitrarily within the range of 5 minutes to 100 hours. Can be set.

一般的には、例えば一般式(4)で表される化合物１当量に対して１〜１０当量の一般式(5)で表される化合物を用い、無溶媒か、或いはテトラヒドロフラン又は1,4-ジオキサン等の溶媒を用い、５０℃から反応混合物の還流温度の温度範囲で、３０分から２４時間反応を行なうのが好ましい。   In general, for example, 1 to 10 equivalents of the compound represented by the general formula (5) is used per 1 equivalent of the compound represented by the general formula (4), and no solvent is used. The reaction is preferably carried out in a temperature range of 50 ° C. to the reflux temperature of the reaction mixture using a solvent such as dioxane for 30 minutes to 24 hours.

製造法B   Manufacturing method B

Figure 2005126418
Figure 2005126418

一般式(6)［式中、W2, X, Y, R4, R5, R6, m及びnは前記と同じ意味を表す。］で表される化合物と一般式(5)［式中、R1及びR2は前記と同じ意味を表す。］で表される化合物とを製造法Aと同様な条件下反応させることにより、一般式(1)においてW1が酸素原子であり、R3が水素原子である一般式(1-2)［式中、W2, X, Y, R1, R2, R4, R5, R6, m及びnは前記と同じ意味を表す。］で表される本発明化合物を得ることができる。 Formula (6) [wherein W 2 , X, Y, R 4 , R 5 , R 6 , m and n represent the same meaning as described above. And a compound represented by the general formula (5): wherein R 1 and R 2 represent the same meaning as described above. And a compound represented by the general formula (1-2) in which W 1 is an oxygen atom and R 3 is a hydrogen atom in the general formula (1). In the formula, W 2 , X, Y, R 1 , R 2 , R 4 , R 5 , R 6 , m and n represent the same meaning as described above. This invention compound represented by this can be obtained.

製造法C   Manufacturing method C

Figure 2005126418
Figure 2005126418

一般式(7)［式中、W1, X, R1及びmは前記と同じ意味を表す。］で表される化合物と一般式(8)［式中、Y, R3, R4, R5, R6及びnは前記と同じ意味を表す。］で表される化合物とを製造法Aと同様な条件下反応させることにより、一般式(1)においてW2が酸素原子であり、R2が水素原子である一般式(1-3)［式中、W1, X, Y, R1, R3, R4, R5, R6, m及びnは前記と同じ意味を表す。］で表される本発明化合物を得ることができる。 General formula (7) [wherein W 1 , X, R 1 and m represent the same meaning as described above. And a compound represented by the general formula (8): wherein Y, R 3 , R 4 , R 5 , R 6 and n have the same meaning as described above. And a compound represented by the general formula (1-3) in which W 2 is an oxygen atom and R 2 is a hydrogen atom in the general formula (1). In the formula, W 1 , X, Y, R 1 , R 3 , R 4 , R 5 , R 6 , m and n represent the same meaning as described above. This invention compound represented by this can be obtained.

製造法D   Manufacturing method D

Figure 2005126418
Figure 2005126418

一般式(9)［式中、W2, X, Y, R3, R4, R5, R6, m及びnは前記と同じ意味を表す。］で表される化合物と一般式(5)［式中、R1及びR2は前記と同じ意味を表す。］で表される化合物とを、該反応に対して不活性な溶媒中又は無溶媒にて、必要ならば塩基の存在下、縮合剤を用いて反応させることにより、一般式(1)においてW1が酸素原子である一般式(1-4)［式中、W2, X, Y, R1, R2, R3, R4, R5, R6, m及びnは前記と同じ意味を表す。］で表される本発明化合物を得ることができる。 General formula (9) [wherein W 2 , X, Y, R 3 , R 4 , R 5 , R 6 , m, and n represent the same meaning as described above. And a compound represented by the general formula (5): wherein R 1 and R 2 represent the same meaning as described above. In the general formula (1), the compound represented by the general formula (1) is reacted with a compound in a solvent inert to the reaction or without a solvent, if necessary, in the presence of a base. General formula (1-4) wherein 1 is an oxygen atom [wherein W 2 , X, Y, R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , m and n have the same meaning as described above] Represents. This invention compound represented by this can be obtained.

反応基質の量は、一般式(9)で表される化合物１当量に対して１〜１００当量の一般式(5)で表される化合物を用いることができる。   The amount of the reaction substrate may be 1 to 100 equivalents of the compound represented by the general formula (5) with respect to 1 equivalent of the compound represented by the general formula (9).

縮合剤は、通常のアミド合成に使用されるものであれば特に制限はないが、例えば向山試薬（2-クロロ-N-メチルピリジニウム アイオダイド）、DCC（1,3-ジシクロヘキシルカルボジイミド）、WSC（1-エチル-3-(3-ジメチルアミノプロピル)-カルボジイミド 塩酸塩）、CDI（カルボニルジイミダゾール）、ジメチルプロピニルスルホニウム ブロマイド、プロパルギルトリフェニルホスホニウム ブロマイド、DEPC（シアノ燐酸ジエチル）等を、一般式(9)で表される化合物に対して１〜４当量用いることができる。   The condensing agent is not particularly limited as long as it is used for ordinary amide synthesis. For example, Mukaiyama reagent (2-chloro-N-methylpyridinium iodide), DCC (1,3-dicyclohexylcarbodiimide), WSC (1 -Ethyl-3- (3-dimethylaminopropyl) -carbodiimide hydrochloride), CDI (carbonyldiimidazole), dimethylpropynylsulfonium bromide, propargyltriphenylphosphonium bromide, DEPC (diethyl cyanophosphate), etc. 1-4 equivalent can be used with respect to the compound represented by these.

溶媒を用いる場合、用いられる溶媒としては反応の進行を阻害しないものであれば何でもよく、例えばベンゼン、トルエン、キシレン等の芳香族炭化水素類、ヘキサン、ヘプタン等の脂肪族炭化水素類、シクロヘキサン等の脂環式炭化水素類、クロロベンゼン、ジクロロベンゼン等の芳香族ハロゲン化炭化水素類、ジクロロメタン、クロロホルム、四塩化炭素、1,2-ジクロロエタン、1,1,1-トリクロロエタン、トリクロロエチレン、テトラクロロエチレン等の脂肪族ハロゲン化炭化水素類、ジエチルエーテル、1,2-ジメトキシエタン、テトラヒドロフラン、1,4-ジオキサン等のエーテル類、酢酸エチル、プロピオン酸エチル等のエステル類、ジメチルホルムアミド、ジメチルアセトアミド、Ｎ-メチル-2-ピロリドン等のアミド類、トリエチルアミン、トリブチルアミン、Ｎ,Ｎ-ジメチルアニリン等のアミン類、ピリジン、ピコリン等のピリジン類、アセトニトリル及びジメチルスルホキシド等が挙げられる。これらの溶媒は単独で用いても、これらのうちの２種類以上を混合して用いてもよい。   In the case of using a solvent, any solvent may be used as long as it does not inhibit the progress of the reaction. For example, aromatic hydrocarbons such as benzene, toluene and xylene, aliphatic hydrocarbons such as hexane and heptane, cyclohexane, etc. Alicyclic hydrocarbons, aromatic halogenated hydrocarbons such as chlorobenzene and dichlorobenzene, fats such as dichloromethane, chloroform, carbon tetrachloride, 1,2-dichloroethane, 1,1,1-trichloroethane, trichloroethylene and tetrachloroethylene Group halogenated hydrocarbons, ethers such as diethyl ether, 1,2-dimethoxyethane, tetrahydrofuran and 1,4-dioxane, esters such as ethyl acetate and ethyl propionate, dimethylformamide, dimethylacetamide, N-methyl- Amides such as 2-pyrrolidone, triethylamine, Examples include amines such as tributylamine and N, N-dimethylaniline, pyridines such as pyridine and picoline, acetonitrile, and dimethyl sulfoxide. These solvents may be used alone or as a mixture of two or more thereof.

塩基の添加は必ずしも必要ではないが、塩基を用いる場合、用いられる塩基としては、例えば水酸化ナトリウム、水酸化カリウム等のアルカリ金属水酸化物、炭酸ナトリウム、炭酸カリウム、炭酸水素ナトリウム等のアルカリ金属炭酸塩、トリエチルアミン、トリブチルアミン、Ｎ,Ｎ-ジメチルアニリン、ピリジン、4-(ジメチルアミノ)ピリジン、イミダゾール、1,8-ジアザビシクロ[5,4,0]-7-ウンデセン等の有機塩基等を、一般式(9)で表される化合物に対して１〜４当量用いることができる。   Although the addition of a base is not always necessary, when a base is used, examples of the base used include alkali metal hydroxides such as sodium hydroxide and potassium hydroxide, alkali metals such as sodium carbonate, potassium carbonate and sodium hydrogen carbonate. Organic bases such as carbonate, triethylamine, tributylamine, N, N-dimethylaniline, pyridine, 4- (dimethylamino) pyridine, imidazole, 1,8-diazabicyclo [5,4,0] -7-undecene, etc. 1 to 4 equivalents can be used with respect to the compound represented by the general formula (9).

反応温度は−６０℃から反応混合物の還流温度までの任意の温度を設定することができ、反応時間は、反応基質の濃度、反応温度によって変化するが、通常５分から１００時間の範囲で任意に設定できる。   The reaction temperature can be set to an arbitrary temperature from −60 ° C. to the reflux temperature of the reaction mixture, and the reaction time varies depending on the concentration of the reaction substrate and the reaction temperature, but is usually arbitrarily within the range of 5 minutes to 100 hours. Can be set.

一般的には、例えば一般式(9)で表される化合物１当量に対して１〜２０当量の一般式(5)で表される化合物及び１〜４当量のWSC（1-エチル-3-(3-ジメチルアミノプロピル)-カルボジイミド 塩酸塩）、CDI（カルボニルジイミダゾール）等の縮合剤を用い、必要ならば１〜４当量の炭酸カリウム、トリエチルアミン、ピリジン、4-(ジメチルアミノ)ピリジン等の塩基存在下にて、無溶媒か又はジクロロメタン、クロロホルム、ジエチルエーテル、テトラヒドロフラン、1,4-ジオキサン等の溶媒を用い、０℃からこれらの溶媒の還流温度の範囲で、１０分から２４時間反応を行なうのが好ましい。   In general, for example, 1 to 20 equivalents of the compound represented by the general formula (5) and 1 to 4 equivalents of WSC (1-ethyl-3-ethyl) with respect to 1 equivalent of the compound represented by the general formula (9). (3-dimethylaminopropyl) -carbodiimide hydrochloride), CDI (carbonyldiimidazole) and other condensing agents. If necessary, 1-4 equivalents of potassium carbonate, triethylamine, pyridine, 4- (dimethylamino) pyridine, etc. In the presence of a base, the reaction is carried out for 10 minutes to 24 hours using no solvent or a solvent such as dichloromethane, chloroform, diethyl ether, tetrahydrofuran, 1,4-dioxane, etc., in the range of 0 ° C. to the reflux temperature of these solvents. Is preferred.

製造法E   Manufacturing method E

Figure 2005126418
Figure 2005126418

一般式(10)［式中、W1, X, R1, R2及びmは前記と同じ意味を表す。］で表される化合物と一般式(8)［式中、Y, R3, R4, R5, R6及びnは前記と同じ意味を表す。］で表される化合物とを製造法Dと同様な条件下反応させることにより、一般式(1)においてW2が酸素原子である一般式(1-5)［式中、W1, X, Y, R1, R2, R3, R4, R5, R6, m及びnは前記と同じ意味を表す。］で表される本発明化合物を得ることができる。 General formula (10) [wherein W 1 , X, R 1 , R 2 and m represent the same meaning as described above. And a compound represented by the general formula (8): wherein Y, R 3 , R 4 , R 5 , R 6 and n have the same meaning as described above. And a compound represented by general formula (1-5) in which W 2 is an oxygen atom in general formula (1) [wherein W 1 , X, Y, R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , m and n have the same meaning as described above. This invention compound represented by this can be obtained.

製造法F   Manufacturing method F

Figure 2005126418
Figure 2005126418

一般式(11)［式中、X, R1及びmは前記と同じ意味を表す。］で表される化合物を文献記載の公知の方法、例えばケミカル・レビューズ[Chem. Rev.]１９９０年、９０巻、８７９頁等に記載の方法に準じて位置選択的リチオ化後、一般式(12)［式中、W2, Y, R4, R5, R6及びnは前記と同じ意味を表す。］で表される化合物と反応させることにより、一般式(1)においてW1が酸素原子であり、R2及びR3が水素原子である一般式(1-6)［式中、W2, X, Y, R1, R4, R5, R6, m及びnは前記と同じ意味を表す。］で表される本発明化合物を得ることができる。なお、R-Liはブチルリチウム等のアルキルリチウム試薬を表す。 Formula (11) [wherein X, R 1 and m represent the same meaning as described above. ] After regioselective lithiation according to a known method described in the literature, for example, the method described in Chemical Reviews [Chem. Rev.] 1990, 90, 879, etc. (12) [wherein W 2 , Y, R 4 , R 5 , R 6 and n represent the same meaning as described above. In general formula (1), W 1 is an oxygen atom, and R 2 and R 3 are hydrogen atoms. In the general formula (1-6), W 2 , X, Y, R 1 , R 4 , R 5 , R 6 , m and n represent the same meaning as described above. This invention compound represented by this can be obtained. R-Li represents an alkyl lithium reagent such as butyl lithium.

製造法G   Manufacturing method G

Figure 2005126418
Figure 2005126418

一般式(13)［式中、X, Y, R4, R5, R6, m及びnは前記と同じ意味を表す。］で表される化合物と一般式(14)［式中、W1及びR1は前記と同じ意味を表す。］で表される化合物とを製造法Fと同様な条件下反応させることにより、一般式(1)において、W2が酸素原子であり、R2及びR3が水素原子である一般式(1-7)［式中、W1, X, Y, R1, R4, R5, R6, m及びnは前記と同じ意味を表す。］で表される本発明化合物を得ることができる。なお、R-Liはブチルリチウム等のアルキルリチウム試薬を表す。 General formula (13) [wherein X, Y, R 4 , R 5 , R 6 , m and n represent the same meaning as described above. And a compound represented by the general formula (14): wherein W 1 and R 1 have the same meaning as described above. In the general formula (1), W 2 is an oxygen atom, and R 2 and R 3 are hydrogen atoms. -7) [wherein W 1 , X, Y, R 1 , R 4 , R 5 , R 6 , m and n represent the same meaning as described above. This invention compound represented by this can be obtained. R-Li represents an alkyl lithium reagent such as butyl lithium.

製造法H   Manufacturing method H

Figure 2005126418
Figure 2005126418

一般式(1)においてW2が酸素原子であり、R3が水素原子である一般式(1-8)［式中、W1, X, Y, R1, R2, R4, R5, R6, m及びnは前記と同じ意味を表す。］で表される本発明化合物と一般式(15)［式中、R3は前記と同じ意味を表し、J1は塩素原子、臭素原子、ヨウ素原子、C1〜C4アルキルカルボニルオキシ基（例えば、ピバロイルオキシ基）、C1〜C4アルキルスルホネート基（例えば、メタンスルホニルオキシ基）、C1〜C4ハロアルキルスルホネート基（例えば、トリフルオロメタンスルホニルオキシ基）、アリールスルホネート基（例えば、ベンゼンスルホニルオキシ基、p-トルエンスルホニルオキシ基）又はアゾリル基（例えば、イミダゾール-1-イル基）のような良好な脱離基を表す。］で表される化合物とを、必要ならば塩基の存在下、必要ならば該反応に対して不活性な溶媒を用いて反応させることにより、一般式(1)においてW1が酸素原子である一般式(1-5)［式中、W1, X, Y, R1, R2, R3, R4, R5, R6, m及びnは前記と同じ意味を表す。］で表される本発明化合物を得ることができる。 In general formula (1), W 2 is an oxygen atom and R 3 is a hydrogen atom. General formula (1-8) [wherein W 1 , X, Y, R 1 , R 2 , R 4 , R 5 , R 6 , m and n have the same meaning as described above. The compound of the present invention represented by the general formula (15) [wherein R 3 represents the same meaning as described above, J 1 represents a chlorine atom, a bromine atom, an iodine atom, a C 1 -C 4 alkylcarbonyloxy group ( For example, pivaloyloxy group), C 1 -C 4 alkyl sulfonate group (e.g., methanesulfonyloxy group), C 1 -C 4 haloalkylsulfonate group (e.g., trifluoromethanesulfonyloxy group), an aryl sulfonate group (e.g., benzenesulfonyloxy Group, p-toluenesulfonyloxy group) or an azolyl group (for example, imidazol-1-yl group). In the general formula (1), W 1 is an oxygen atom by reacting the compound represented by the formula (1) with a solvent inert to the reaction if necessary in the presence of a base. Formula (1-5) [wherein W 1 , X, Y, R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , m and n represent the same meaning as described above. This invention compound represented by this can be obtained.

反応基質の量は、一般式(1-8)で表される化合物１当量に対して１〜５０当量の一般式(15)で表される化合物を用いることができる。   As the amount of the reaction substrate, 1 to 50 equivalents of the compound represented by the general formula (15) can be used per 1 equivalent of the compound represented by the general formula (1-8).

溶媒を用いる場合、用いられる溶媒としては反応の進行を阻害しないものであれば何でもよく、例えばベンゼン、トルエン、キシレン等の芳香族炭化水素類、ヘキサン、ヘプタン等の脂肪族炭化水素類、シクロヘキサン等の脂環式炭化水素類、クロロベンゼン、ジクロロベンゼン等の芳香族ハロゲン化炭化水素類、ジクロロメタン、クロロホルム、四塩化炭素、1,2-ジクロロエタン、1,1,1-トリクロロエタン、トリクロロエチレン、テトラクロロエチレン等の脂肪族ハロゲン化炭化水素類、ジエチルエーテル、1,2-ジメトキシエタン、テトラヒドロフラン、1,4-ジオキサン等のエーテル類、酢酸エチル、プロピオン酸エチル等のエステル類、ジメチルホルムアミド、ジメチルアセトアミド、Ｎ-メチル-2-ピロリドン等のアミド類、トリエチルアミン、トリブチルアミン、Ｎ,Ｎ-ジメチルアニリン等のアミン類、ピリジン、ピコリン等のピリジン類、メタノール、エタノール、エチレングリコール等のアルコール類、アセトニトリル、ジメチルスルホキシド、スルホラン、1,3-ジメチル-2-イミダゾリジノン及び水等が挙げられる。これらの溶媒は単独で用いても、これらのうちの２種類以上を混合して用いてもよい。   In the case of using a solvent, any solvent may be used as long as it does not inhibit the progress of the reaction. For example, aromatic hydrocarbons such as benzene, toluene and xylene, aliphatic hydrocarbons such as hexane and heptane, cyclohexane, etc. Alicyclic hydrocarbons, aromatic halogenated hydrocarbons such as chlorobenzene and dichlorobenzene, fats such as dichloromethane, chloroform, carbon tetrachloride, 1,2-dichloroethane, 1,1,1-trichloroethane, trichloroethylene and tetrachloroethylene Group halogenated hydrocarbons, ethers such as diethyl ether, 1,2-dimethoxyethane, tetrahydrofuran and 1,4-dioxane, esters such as ethyl acetate and ethyl propionate, dimethylformamide, dimethylacetamide, N-methyl- Amides such as 2-pyrrolidone, triethylamine, Amines such as tributylamine and N, N-dimethylaniline, pyridines such as pyridine and picoline, alcohols such as methanol, ethanol and ethylene glycol, acetonitrile, dimethyl sulfoxide, sulfolane, 1,3-dimethyl-2-imidazolide Non- and water are listed. These solvents may be used alone or as a mixture of two or more thereof.

塩基を用いる場合、用いられる塩基としては、例えば水素化ナトリウム、水素化カリウム等のアルカリ金属水素化物、水酸化ナトリウム、水酸化カリウム等のアルカリ金属水酸化物、ナトリウムエトキシド、カリウムターシャリーブトキシド等のアルカリ金属アルコキシド類、リチウムジイソプロピルアミド、リチウムヘキサメチルジシラザン、ナトリウムアミド等のアルカリ金属アミド類、ターシャリーブチルリチウム等の有機金属化合物、炭酸ナトリウム、炭酸カリウム、炭酸水素ナトリウム等のアルカリ金属炭酸塩、トリエチルアミン、トリブチルアミン、N,N-ジメチルアニリン、ピリジン、4-(ジメチルアミノ)ピリジン、イミダゾール、1,8-ジアザビシクロ[5,4,0]-7-ウンデセン等の有機塩基等を、一般式(1-8)で表される化合物に対して１〜４当量用いることができる。   When a base is used, examples of the base used include alkali metal hydrides such as sodium hydride and potassium hydride, alkali metal hydroxides such as sodium hydroxide and potassium hydroxide, sodium ethoxide, potassium tertiary butoxide and the like. Alkali metal alkoxides, alkali metal amides such as lithium diisopropylamide, lithium hexamethyldisilazane, sodium amide, organometallic compounds such as tertiary butyl lithium, alkali metal carbonates such as sodium carbonate, potassium carbonate, sodium bicarbonate Organic bases such as triethylamine, tributylamine, N, N-dimethylaniline, pyridine, 4- (dimethylamino) pyridine, imidazole, 1,8-diazabicyclo [5,4,0] -7-undecene, etc. 1 to the compound represented by (1-8) It can be used equivalents.

反応温度は−６０℃から反応混合物の還流温度までの任意の温度を設定することができ、反応時間は、反応基質の濃度、反応温度によって変化するが、通常５分から１００時間の範囲で任意に設定できる。   The reaction temperature can be set to an arbitrary temperature from −60 ° C. to the reflux temperature of the reaction mixture, and the reaction time varies depending on the concentration of the reaction substrate and the reaction temperature, but is usually arbitrarily within the range of 5 minutes to 100 hours. Can be set.

一般的には、例えば一般式(1-8)で表される化合物１当量に対して１〜１０当量の一般式(15)で表される化合物を用い、テトラヒドロフラン、1,4-ジオキサン、アセトニトリルやＮ,Ｎ-ジメチルホルムアミド等の極性溶媒中、必要ならば塩基として水素化ナトリウム、カリウムターシャリーブトキシド、水酸化カリウム、炭酸カリウム、トリエチルアミンやピリジン等を一般式(1-8)で表される化合物１当量に対して１〜３当量用いて、０〜９０℃の温度範囲で、１０分から２４時間反応を行なうのが好ましい。   In general, for example, 1 to 10 equivalents of the compound represented by the general formula (15) is used per 1 equivalent of the compound represented by the general formula (1-8), tetrahydrofuran, 1,4-dioxane, acetonitrile In a polar solvent such as N, N-dimethylformamide, sodium hydride, potassium tertiary butoxide, potassium hydroxide, potassium carbonate, triethylamine, pyridine and the like are represented by the general formula (1-8) as a base if necessary. It is preferable to perform the reaction for 10 minutes to 24 hours in a temperature range of 0 to 90 ° C. using 1 to 3 equivalents per 1 equivalent of the compound.

製造法I   Manufacturing method I

Figure 2005126418
Figure 2005126418

一般式(1)においてW1が酸素原子であり、R2が水素原子である一般式(1-9)［式中、W2, X, Y, R1, R3, R4, R5, R6, m及びnは前記と同じ意味を表す。］で表される本発明化合物と一般式(16)［式中、R2及びJ1は前記と同じ意味を表す。］で表される化合物とを製造法Hと同様な条件下反応させることにより、一般式(1)においてW1が酸素原子である一般式(1-4)［式中、W2, X, Y, R1, R2, R3, R4, R5, R6, m及びnは前記と同じ意味を表す。］で表される本発明化合物を得ることができる。 In general formula (1), W 1 is an oxygen atom and R 2 is a hydrogen atom. General formula (1-9) [wherein W 2 , X, Y, R 1 , R 3 , R 4 , R 5 , R 6 , m and n have the same meaning as described above. The compound of the present invention represented by general formula (16): wherein R 2 and J 1 represent the same meaning as described above. And a compound represented by the general formula (1-4) in which W 1 is an oxygen atom in the general formula (1) [wherein W 2 , X, Y, R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , m and n have the same meaning as described above. This invention compound represented by this can be obtained.

製造法A〜製造法Iにおいて、反応終了後の反応混合物は、直接濃縮、又は有機溶媒に溶解し、水洗後濃縮、又は氷水に投入、有機溶媒抽出後濃縮といった通常の後処理を行ない、目的の本発明化合物を得ることができる。また、精製の必要が生じたときには、再結晶、カラムクロマトグラフ、薄層クロマトグラフ、液体クロマトグラフ分取等の任意の精製方法によって分離、精製することができる。   In production method A to production method I, the reaction mixture after completion of the reaction is directly concentrated, or dissolved in an organic solvent, concentrated after washing with water, or poured into ice water, followed by normal post-treatment such as extraction after organic solvent extraction. Of the present invention can be obtained. Moreover, when the necessity for purification arises, it can be separated and purified by any purification method such as recrystallization, column chromatograph, thin layer chromatograph, liquid chromatographic fractionation and the like.

製造法Aにおいて本発明化合物を製造するための原料化合物である一般式(4)においてW1及びW2が酸素原子でである一般式(4-1)で表される化合物は、次のようにして合成できる。 The compound represented by general formula (4-1) in which W 1 and W 2 are oxygen atoms in general formula (4), which is a raw material compound for manufacturing the compound of the present invention in production method A, is as follows: Can be synthesized.

反応式１   Reaction formula 1

Figure 2005126418
Figure 2005126418

すなわち、一般式(17)［式中、X及びmは前記と同じ意味を表す。］で表される化合物と一般式(8)においてR3が水素原子である一般式(8-1)［式中、Y, R4, R5, R6及びnは前記と同じ意味を表す。］で表される化合物とを文献記載の公知の方法、例えばベリヒテ・デア・ドイッチェン・ヘミッシェン・ゲゼルシャフト［Ber. Dtsch. Chem. Ges.］１９０７年、４０巻、３１７７頁、ジャーナル・オブ・ザ・ケミカル・ソサイエティー [J. Chem. Soc.]１９５４年、２０２３頁、ジャーナル・オブ・ザ・ケミカル・ソサイエティー・パーキン・トランスアクションズ、１[J. Chem. Soc. Perkin Trans. 1]１９９４年、２９７５頁等に記載の方法に準じて反応させることにより、一般式(4)においてW1及びW2が酸素原子である一般式(4-1)［式中、X, Y, R4, R5, R6, m及びnは前記と同じ意味を表す。］で表される化合物を容易に合成することができる。 That is, in the general formula (17) [wherein X and m represent the same meaning as described above. And a compound represented by the general formula (8-1) in which R 3 is a hydrogen atom in the general formula (8) [wherein Y, R 4 , R 5 , R 6 and n represent the same meaning as described above] . And the compound represented by the literature, for example, Berichte der Deutschen Hemischen Gesellshaft [Ber. Dtsch. Chem. Ges.] 1907, 40, 3177, Journal of the. Chemical Society [J. Chem. Soc.] 1954, 2023, Journal of the Chemical Society Perkin Transactions, 1 [J. Chem. Soc. Perkin Trans. 1] 1994, 2975 In the general formula (4), W 1 and W 2 are oxygen atoms in the general formula (4-1) [wherein X, Y, R 4 , R 5 , R 6 , m and n have the same meaning as described above. ] Can be easily synthesized.

製造法A、製造法B及び製造法Dで用いられる一般式(5)で表される化合物の或るものは公知化合物であり、一部は市販品として入手できる。また、それ以外のものも、例えばケミカル・アンド・ファーマシューティカル・ブレティン [Chem. Pharm. Bull.] １９８２年、３０巻、１９２１頁、ジャーナル・オブ・ジ・アメリカン・ケミカル・ソサイエティー[J. Am. Chem. Soc.]１９８６年、１０８巻、３８１１頁、国際特許出願公報（WO 01/23350号公報）等に記載の方法及び文献記載のその他１級又は２級アルキルアミン類それぞれの一般的な合成方法に準じて合成することができる。   Some of the compounds represented by the general formula (5) used in Production Method A, Production Method B, and Production Method D are known compounds, and some of them are commercially available. Others, for example, Chemical and Pharmaceutical Bulletin [Chem. Pharm. Bull.] 1982, 30, 1921, Journal of the American Chemical Society [J. Am Chem. Soc.] 1986, 108, 3811, the method described in International Patent Application Publication (WO 01/23350) and the like, and other primary or secondary alkylamines described in the literature. It can be synthesized according to the synthesis method.

製造法Bにおいて、本発明化合物を製造するための原料化合物である、一般式(6)で表される化合物は、次のようにして合成できる。   In the production method B, the compound represented by the general formula (6), which is a raw material compound for producing the compound of the present invention, can be synthesized as follows.

反応式２   Reaction formula 2

Figure 2005126418
Figure 2005126418

すなわち、一般式(9)においてR3が水素原子である一般式(9-1)［式中、W2, X, Y, R4, R5, R6, m及びnは前記と同じ意味を表す。］で表される化合物を文献記載の一般的な脱水環化によるイソイミドの合成反応、例えばジャーナル・オブ・ジ・アメリカン・ケミカル・ソサイエティー[J. Am. Chem. Soc.]１９７５年、９７巻、５５８２頁、ジャーナル・オブ・メディシナル・ケミストリー［J. Med. Chem.］１９６７年、１０巻、９８２頁、ザ・ジャーナル・オブ・オーガニック・ケミストリー［J. Org. Chem.］１９６３年、２８巻、２０１８頁等に記載の方法等に準じて環化することにより、一般式(6)［式中、W2, X, Y, R4, R5, R6, m及びnは前記と同じ意味を表す。］で表される化合物を容易に合成することができる。 That is, in the general formula (9), R 3 is a hydrogen atom, the general formula (9-1) [wherein W 2 , X, Y, R 4 , R 5 , R 6 , m and n have the same meaning as described above. Represents. ], For example, Journal of the American Chemical Society [J. Am. Chem. Soc.] 1975, Vol. 97, 5582, Journal of Medicinal Chemistry [J. Med. Chem.] 1967, 10, 982, The Journal of Organic Chemistry [J. Org. Chem.] 1963, 28, By cyclization according to the method described on page 2018, etc., general formula (6) [wherein W 2 , X, Y, R 4 , R 5 , R 6 , m and n have the same meaning as described above] Represents. ] Can be easily synthesized.

製造法Cにおいて、本発明化合物を製造するための原料化合物である、一般式(7)で表される化合物は、次のようにして合成できる。   In Production Method C, the compound represented by the general formula (7), which is a raw material compound for producing the compound of the present invention, can be synthesized as follows.

反応式３   Reaction formula 3

Figure 2005126418
Figure 2005126418

すなわち、一般式(10)においてR2が水素原子である一般式(10-1)［式中、W1, X, R1及びmは前記と同じ意味を表す。］で表される化合物を反応式２と同様に反応させることにより、一般式(7)［式中、W1, X, R1及びmは前記と同じ意味を表す。］で表される化合物を容易に合成することができる。 That is, in general formula (10), general formula (10-1) wherein R 2 is a hydrogen atom [wherein W 1 , X, R 1 and m represent the same meaning as described above. The compound represented by the general formula (7) [wherein W 1 , X, R 1 and m represent the same meaning as described above]. ] Can be easily synthesized.

製造法C及び製造法Eで用いられる一般式(8)で表される化合物は、例えば下記の反応式４〜反応式７で表される方法等を用いて合成することができる。   The compound represented by the general formula (8) used in the production method C and the production method E can be synthesized using, for example, the methods represented by the following reaction formulas 4 to 7.

反応式４   Reaction formula 4

Figure 2005126418
Figure 2005126418

一般式(18)［式中、Y, R3, R4及びnは前記と同じ意味を表し、Pはアセチル基、ピバロイル基、ベンゾイル基、ターシャリーブトキシカルボニル基、ベンジルオキシカルボニル基等の一般に用いられるアミノ基の保護基を表す。］で表される化合物と、一般式(19)［式中、R5は前記と同じ意味を表す。］で表されるリチウム反応剤又は一般式(20)［式中、R5は前記と同じ意味を表し、J2は臭素原子、ヨウ素原子等のハロゲン原子を表す。］で表されるグリニャール反応剤とを文献記載の公知の方法、例えば、ヘテロサイクルズ［Heterocycles］１９９４年、３９巻、８０１頁、ジャーナル・オブ・ジ・アメリカン・ケミカル・ソサイエティー[J. Am. Chem. Soc.]１９８８年、１１０巻、１８６２頁、テトラヘドロン［Tetrahedron］１９６０年、１１巻、２５２頁、テトラヘドロン・レターズ［Tetrahedron Lett.］１９９５年、３６巻、９１１７頁等に記載の方法に準じて反応させた後、各々の保護基について一般的に用いられる方法で脱保護することにより、一般式(8)においてR6が水素原子である一般式(8-2)［式中、Y, R3, R4, R5及びnは前記と同じ意味を表す。］で表される化合物を得ることができる。 General formula (18) [wherein Y, R 3 , R 4 and n represent the same meaning as described above, and P is generally an acetyl group, a pivaloyl group, a benzoyl group, a tertiary butoxycarbonyl group, a benzyloxycarbonyl group, etc. The protecting group of the amino group used is represented. And a compound represented by the general formula (19) [wherein R 5 represents the same meaning as described above. Or a general formula (20) [wherein R 5 represents the same meaning as described above, and J 2 represents a halogen atom such as a bromine atom or an iodine atom. And the Grignard reactant represented by the literature, for example, Heterocycles 1994, 39, 801, Journal of the American Chemical Society [J. Am. Chem. Soc.] 1988, 110, 1862, Tetrahedron 1960, 11, 252; Tetrahedron Lett. 1995, 36, 9117, etc. And then reacting according to the general formula (8-2) wherein R 6 is a hydrogen atom in the general formula (8). Y, R 3 , R 4 , R 5 and n have the same meaning as described above. The compound represented by this can be obtained.

また、一般式(21)［式中、Y, R3, R5, n及びPは前記と同じ意味を表す。］で表される化合物と、一般式(22)［式中、R4は前記と同じ意味を表す。］で表されるリチウム反応剤又は一般式(23)［式中、R4及びJ2は前記と同じ意味を表す。］で表されるグリニャール反応剤とを上記と同様な条件下反応させることによっても一般式(8-2)で表される化合物を得ることができる。 Further, in the general formula (21) [wherein Y, R 3 , R 5 , n and P represent the same meaning as described above. And a compound represented by the general formula (22), wherein R 4 represents the same meaning as described above. Or a general formula (23) wherein R 4 and J 2 represent the same meaning as described above. The compound represented by the general formula (8-2) can also be obtained by reacting with a Grignard reactant represented by the same conditions as described above.

ここで用いられる一般式(19)及び一般式(22)で表されるリチウム反応剤の或るものは公知化合物であり、一部は市販品として入手できる。また、それ以外のものも文献記載の一般的なハロゲン−メタル交換反応、例えばブレティン・オブ・ザ・ケミカル・ソサイエティー・オブ・ジャパン［Bull. Chem. Soc. Jpn.］１９９０年、６３巻、３７１９頁、ザ・ジャーナル・オブ・オーガニック・ケミストリー［J. Org. Chem.］１９８３年、４８巻、１４４９頁等に記載の方法に準じて対応する公知のハロゲン化物から容易に合成することができる。   Some of the lithium reactants represented by general formula (19) and general formula (22) used here are known compounds, and some of them are available as commercial products. In addition, other halogen-metal exchange reactions described in the literature, such as Bulletin of the Chemical Society of Japan [Bull. Chem. Soc. Jpn.] 1990, 63, 3719 Page, The Journal of Organic Chemistry [J. Org. Chem.] 1983, Vol. 48, p. 1449, etc., can be easily synthesized from the corresponding known halides.

また、一般式(20)及び一般式(23)で表されるグリニャール反応剤の或るものは公知化合物であり、一部は市販品として入手できる。また、それ以外のものも文献記載の一般的なグリニャール試薬の調製方法、例えばアンゲバンテ・ヘミー・インターナショナル・エディション・イン・イングリッシュ[Angew. Chem. Int. Ed. Engl.]１９６９年、８巻、２７９頁、ザ・ジャーナル・オブ・オーガニック・ケミストリー［J. Org. Chem.］１９８９年、５４巻、４４１３頁等に記載の方法に準じて対応する公知のハロゲン化物から容易に合成することができる。   Some of the Grignard reagents represented by the general formula (20) and the general formula (23) are known compounds, and some of them are available as commercial products. In addition, other methods for preparing general Grignard reagents described in the literature, such as Angewante Chemie Int. Ed. Engl., 1969, Vol. 8, 279 Page, The Journal of Organic Chemistry [J. Org. Chem.] 1989, 54, 4413, etc., and can be easily synthesized from the corresponding known halides.

反応式５   Reaction formula 5

Figure 2005126418
Figure 2005126418

一般式(21)［式中、Y, R3, R5, n及びPは前記と同じ意味を表す。］で表される化合物を、式(24)で表される化合物と文献記載の公知の方法、例えば、シンレット［Synlett］２００３年、２３３頁に記載の方法に準じて反応させるか、或いは公知の一般式(25)［式中、J3は水素原子、臭素原子、トリメチルシリル基等を表す。］で表される化合物と文献記載の公知の方法、例えば、ザ・ジャーナル・オブ・オーガニック・ケミストリー［J. Org. Chem.］２０００年、６５巻、８８４８頁及び２００１年、６６巻、１４３６頁、テトラヘドロン［Tetrahedron］１９８９年、４５巻、１４２３頁等に記載の方法に準じて反応させた後、各々の保護基について一般的に用いられる方法で脱保護することにより、一般式(8)においてR4がトリフルオロメチル基であり、R6が水素原子である一般式(8-3)［式中、Y, R3, R5及びnは前記と同じ意味を表す。］で表される化合物を得ることができる。 General formula (21) [wherein Y, R 3 , R 5 , n and P represent the same meaning as described above. The compound represented by formula (24) is reacted with a compound represented by the formula (24) according to a known method described in the literature, for example, a method described in Synlett, p. 233, 2003, or a known method. General formula (25) [wherein J 3 represents a hydrogen atom, a bromine atom, a trimethylsilyl group or the like. ] And known methods described in the literature, for example, The Journal of Organic Chemistry [J. Org. Chem.] 2000, 65, 8848 and 2001, 66, 1436 Tetrahedron, 1989, Vol. 45, p. 1423, and the like, followed by deprotection of each protecting group by a commonly used method to give a compound represented by the general formula (8) Wherein R 4 is a trifluoromethyl group and R 6 is a hydrogen atom (wherein Y, R 3 , R 5 and n are as defined above). The compound represented by this can be obtained.

反応式６   Reaction formula 6

Figure 2005126418
Figure 2005126418

一般式(26)［式中、Y, R3, n, J2及びPは前記と同じ意味を表す。］で表される化合物を文献記載の一般的な方法、例えばリチオ化した後、一般式(27)［式中、R4及びR5は前記と同じ意味を表す。］で表される化合物と反応させるテトラヘドロン・レターズ［Tetrahedron Lett.］１９９５年、３６巻、９１１７頁等に記載の方法、或いはグリニャール反応剤を形成した後、一般式(27)で表される化合物と反応させるテトラヘドロン［Tetrahedron］１９６０年、１１巻、２５２頁、ザ・ジャーナル・オブ・オーガニック・ケミストリー［J. Org. Chem.］１９８８年、５３巻、７５４頁等に記載の方法に準じて反応させた後、各々の保護基について一般的に用いられる方法で脱保護することにより、一般式(8)においてR6が水素原子である一般式(8-2)［式中、Y, R3, R4, R5及びnは前記と同じ意味を表す。］で表される化合物を得ることができる。なお、R-Liはブチルリチウム等のアルキルリチウム試薬を表す。 General formula (26) [wherein Y, R 3 , n, J 2 and P represent the same meaning as described above. ] After lithiation of the compound represented by the literature, for example, by lithiation, general formula (27) [wherein R 4 and R 5 represent the same meaning as described above. The method described in Tetrahedron Lett. 1995, Vol. 36, page 9117, etc., or after forming a Grignard reactant, is represented by the general formula (27). According to the method described in Tetrahedron, 1960, 11, 252; The Journal of Organic Chemistry [J. Org. Chem.] 1988, 53, 754, etc. Then, each protecting group is deprotected by a commonly used method to give a general formula (8-2) wherein R 6 is a hydrogen atom in the general formula (8) [wherein Y, R 3 , R 4 , R 5 and n have the same meaning as described above. The compound represented by this can be obtained. R-Li represents an alkyl lithium reagent such as butyl lithium.

反応式７   Reaction formula 7

Figure 2005126418
Figure 2005126418

反応式４、反応式５及び反応式６において中間体として得られる一般式(28)［式中、Y, R3, R4, R5, n及びPは前記と同じ意味を表す。］で表される化合物と一般式(29)［式中、R6及びJ1は前記と同じ意味を表す。］で表される化合物とを製造法Hと同様な条件下反応させた後、各々の保護基について一般的に用いられる方法で脱保護することにより、一般式(8)［式中、Y, R3, R4, R5及びnは前記と同じ意味を表し、R6は水素原子以外の前記の意味を表す。］で表される化合物を得ることができる。 General formula (28) obtained as an intermediate in reaction formula 4, reaction formula 5 and reaction formula 6, wherein Y, R 3 , R 4 , R 5 , n and P have the same meaning as described above. And a compound represented by the general formula (29): wherein R 6 and J 1 represent the same meaning as described above. And a compound represented by the general formula (8) [wherein Y, R 3 , R 4 , R 5 and n represent the same meaning as described above, and R 6 represents the above meaning other than a hydrogen atom. The compound represented by this can be obtained.

製造法Dにおいて、本発明化合物を製造するための原料化合物である、一般式(9)で表される化合物は、例えば下記の反応式８又は反応式９で表される方法等を用いて合成することができる。   In production method D, the compound represented by general formula (9), which is a raw material compound for producing the compound of the present invention, is synthesized using, for example, the method represented by the following reaction formula 8 or 9 can do.

反応式８   Reaction formula 8

Figure 2005126418
Figure 2005126418

一般式(17)［式中、X及びmは前記と同じ意味を表す。］で表される化合物と一般式(8)［式中、Y, R3, R4, R5, R6及びnは前記と同じ意味を表す。］で表される化合物とを製造法Aと同様な条件下反応させることにより、一般式(9)においてW2が酸素原子である一般式(9-2)［式中、X, Y, R3, R4, R5, R6, m及びnは前記と同じ意味を表す。］で表される化合物を得ることができる。 General formula (17) [wherein X and m represent the same meaning as described above. And a compound represented by the general formula (8): wherein Y, R 3 , R 4 , R 5 , R 6 and n have the same meaning as described above. And a compound represented by the general formula (9-2) wherein W 2 is an oxygen atom in the general formula (9) [wherein X, Y, R 3 , R 4 , R 5 , R 6 , m and n represent the same meaning as described above. The compound represented by this can be obtained.

反応式９   Reaction formula 9

Figure 2005126418
Figure 2005126418

一般式(13)［式中、X, Y, R4, R5, R6, m及びnは前記と同じ意味を表す。］で表される化合物を文献記載の公知の方法、例えば、ケミカル・レビューズ[Chem. Rev.]１９９０年、９０巻、８７９頁等に記載の方法に準じて、位置選択的リチオ化後、炭酸ガスと反応させることにより、一般式(9)においてW2が酸素原子であり、R3が水素原子である一般式(9-3)［式中、X, Y, R4, R5, R6, m及びnは前記と同じ意味を表す。］で表される化合物を得ることができる。なお、R-Liはブチルリチウム等のアルキルリチウム試薬を表す。 General formula (13) [wherein X, Y, R 4 , R 5 , R 6 , m and n represent the same meaning as described above. In accordance with a known method described in the literature, for example, a method described in Chemical Reviews [Chem. Rev.] 1990, 90, 879, etc., after regioselective lithiation, By reacting with carbon dioxide, general formula (9-3) in which W 2 is an oxygen atom and R 3 is a hydrogen atom in general formula (9) [wherein X, Y, R 4 , R 5 , R 6 , m and n have the same meaning as described above. The compound represented by this can be obtained. R-Li represents an alkyl lithium reagent such as butyl lithium.

製造法Eにおいて、本発明化合物を製造するための原料化合物である、一般式(10)で表される化合物は、例えば下記の反応式１０又は反応式１１で表される方法等を用いて合成できる。   In the production method E, the compound represented by the general formula (10), which is a raw material compound for producing the compound of the present invention, is synthesized using, for example, the method represented by the following reaction formula 10 or 11 it can.

反応式１０   Reaction formula 10

Figure 2005126418
Figure 2005126418

一般式(17)［式中、X及びmは前記と同じ意味を表す。］で表される化合物と一般式(5)［式中、R1及びR2は前記と同じ意味を表す。］で表される化合物とを製造法Aと同様な条件下反応させることにより、一般式(10)においてW1が酸素原子である一般式(10-2)［式中、X, R1, R2及びmは前記と同じ意味を表す。］で表される化合物を得ることができる。 General formula (17) [wherein X and m represent the same meaning as described above. And a compound represented by the general formula (5): wherein R 1 and R 2 represent the same meaning as described above. And a compound represented by the general formula (10-2) in which W 1 is an oxygen atom in the general formula (10) [wherein X, R 1 , R 2 and m represent the same meaning as described above. The compound represented by this can be obtained.

反応式１１   Reaction formula 11

Figure 2005126418
Figure 2005126418

一般式(11)［式中、X, R1及びmは前記と同じ意味を表す。］で表される化合物を反応式１２と同様に反応させることにより、一般式(10)においてW1が酸素原子であり、R2が水素原子である一般式(10-3)［式中、X, R1及びmは前記と同じ意味を表す。］で表される化合物を得ることができる。なお、R-Liはブチルリチウム等のアルキルリチウム試薬を表す。 Formula (11) [wherein X, R 1 and m represent the same meaning as described above. In the general formula (10), W 1 is an oxygen atom and R 2 is a hydrogen atom in the general formula (10-3) [wherein X, R 1 and m represent the same meaning as described above. The compound represented by this can be obtained. R-Li represents an alkyl lithium reagent such as butyl lithium.

製造法Fにおいて、本発明化合物を製造するための原料化合物である一般式(11)で表される化合物の或るものは公知化合物であり、一部は市販品として入手できる。また、それ以外のものも文献記載の公知の方法、例えばブレティン・オブ・ザ・ケミカル・ソサイエティー・オブ・ジャパン［Bull. Chem. Soc. Jpn.］１９８５年、５８巻、３２９１頁、ザ・ジャーナル・オブ・オーガニック・ケミストリー［J. Org. Chem.］１９９１年、５６巻、２３９５頁、テトラヘドロン・レターズ［Tetrahedron Lett.］１９９４年、３５巻、２１１３頁、国際特許出願公報（WO 98/23581号公報）等に記載の方法に準じて容易に合成することができる。   In the production method F, some of the compounds represented by the general formula (11) which are raw material compounds for producing the compound of the present invention are known compounds, and some of them are commercially available. In addition, other methods known in the literature, for example, Bulletin of the Chemical Society of Japan [Bull. Chem. Soc. Jpn.] 1985, 58, 3291, The Journal Of organic chemistry [J. Org. Chem.] 1991, 56, 2395, Tetrahedron Lett. 1994, 35, 2113, International Patent Application Publication (WO 98/23581) It can be easily synthesized according to the method described in Japanese Patent Publication No.

製造法Fで用いられる一般式(12)で表される化合物は、次のようにして合成できる。   The compound represented by the general formula (12) used in production method F can be synthesized as follows.

反応式１２   Reaction formula 12

Figure 2005126418
Figure 2005126418

すなわち、一般式(8)においてR3が水素原子である一般式(8-1)［式中、Y, R4, R5, R6及びnは前記と同じ意味を表す。］で表される化合物と一般式(30)［式中、W2は酸素原子又は硫黄原子を表す。］で表される市販のホスゲン、チオオスゲン又はそれらの等価体とを文献記載の公知の方法、例えばアンゲバンテ・ヘミー・インターナショナル・エディション・イン・イングリッシュ[Angew. Chem. Int. Ed. Engl.]１９８７年、２６巻、８９４頁及び１９９５年、３４巻、２４９７頁、ザ・ジャーナル・オブ・オーガニック・ケミストリー［J. Org. Chem.］１９７６年、４１巻、２０７０頁、シンセシス［Synthesis］１９８８年、９９０頁、テトラヘドロン・レターズ［Tetrahedron Lett.］１９９７年、３８巻、９１９頁等に記載の方法に準じて反応させることにより、一般式(12)［式中、W2, Y, R4, R5, R6及びnは前記と同じ意味を表す。］で表される化合物を容易に合成することができる。 That is, in general formula (8), R 3 is a hydrogen atom. General formula (8-1) [wherein Y, R 4 , R 5 , R 6 and n represent the same meaning as described above. And a compound represented by the general formula (30): wherein W 2 represents an oxygen atom or a sulfur atom. And a commercially available phosgene, thioosgen or an equivalent thereof, for example, known methods described in the literature, for example, Angewante Chemie International Edition in English [Angew. Chem. Int. Ed. Engl.] 1987 26, 894 and 1995, 34, 2497, The Journal of Organic Chemistry [J. Org. Chem.] 1976, 41, 2070, Synthesis 1988, 990 Tetrahedron Lett. 1997, 38, 919, and the like, by reacting according to the method described in general formula (12) [wherein W 2 , Y, R 4 , R 5 , R 6 and n have the same meaning as described above. ] Can be easily synthesized.

製造法Gにおいて、本発明化合物を製造するための原料化合物である、一般式(13)で表される化合物は、次のようにして合成できる。   In Production Method G, the compound represented by General Formula (13), which is a raw material compound for producing the compound of the present invention, can be synthesized as follows.

反応式１３   Reaction formula 13

Figure 2005126418
Figure 2005126418

すなわち、一般式(31)［式中、X及びmは前記と同じ意味を表す。］で表される化合物と一般式(8)においてR3が水素原子である一般式(8-1)［式中、Y, R4, R5, R6及びnは前記と同じ意味を表す。］で表される化合物とを製造法Dと同様な条件下反応させるか、或いは一般式(31)で表される化合物を公知の方法（例えば、塩化チオニル、五塩化リン又はオキザリルクロライド等のクロル化剤）を用いて対応するカルボン酸クロライドした後に、一般式(8-1)で表される化合物と反応させることにより、一般式(13)［式中、X, Y, R4, R5, R6, m及びnは前記と同じ意味を表す。］で表される化合物を容易に合成することができる。 That is, in the general formula (31) [wherein X and m represent the same meaning as described above. And a compound represented by the general formula (8-1) in which R 3 is a hydrogen atom in the general formula (8) [wherein Y, R 4 , R 5 , R 6 and n represent the same meaning as described above] . Or a compound represented by the general formula (31) by a known method (for example, thionyl chloride, phosphorus pentachloride or oxalyl chloride). The corresponding carboxylic acid chloride using a chlorinating agent) is reacted with a compound represented by the general formula (8-1) to give a general formula (13) [wherein X, Y, R 4 , R 5 , R 6 , m and n represent the same meaning as described above. ] Can be easily synthesized.

ここで用いられる一般式(31)で表される化合物は公知化合物であり、一部は市販品として入手できる。   The compounds represented by the general formula (31) used here are known compounds, and some of them are available as commercial products.

製造法Gで用いられる一般式(14)で表される化合物の或るものは公知化合物であり、一部は市販品として入手できる。また、それ以外のものも文献記載の一般的な合成方法、例えばザ・ジャーナル・オブ・オーガニック・ケミストリー［J. Org. Chem.］１９９６年、６１巻、３８８３頁、３９２９頁及び６５７５頁、テトラヘドロン・レターズ［Tetrahedron Lett.］１９９９年、４０巻、３６３頁及び６１２１頁等に記載の方法に準じて容易に合成することができる。   Some of the compounds represented by the general formula (14) used in production method G are known compounds, and some of them are commercially available. Other than that, general synthesis methods described in the literature, for example, The Journal of Organic Chemistry [J. Org. Chem.] 1996, 61, 3883, 3929 and 6575, Tetra It can be easily synthesized according to the method described in Tetrahedron Lett. 1999, 40, 363, 6121, etc.

製造法Hで用いられる一般式(15)で表される化合物、製造法Iで用いられる一般式(16)で表される化合物及び反応式７で用いられる一般式(29)で表される化合物の或るものは公知化合物であり、一部は市販品として入手できる。また、それ以外のものも文献記載の一般的な合成方法、例えばケミストリー・レターズ［Chem. Lett.］１９７６年、３７３頁、ジャーナル・オブ・ジ・アメリカン・ケミカル・ソサイエティー[J. Am. Chem. Soc.]１９６４年、８６巻、４３８３頁、ザ・ジャーナル・オブ・オーガニック・ケミストリー［J. Org. Chem.］１９７６年、４１巻、４０２８頁及び１９７８年、４３巻、３２４４頁、オーガニック・シンセシス[Org. Synth.]１９８８年、コレクティブボリューム６巻、１０１頁、テトラヘドロン・レターズ［Tetrahedron Lett.］１９７２年、４３３９頁、英国特許（GB 2,161,802号公報）、ヨーロッパ特許（EP 0,051,273号公報）等に記載の方法に準じて容易に合成することができる。   Compound represented by general formula (15) used in production method H, compound represented by general formula (16) used in production method I, and compound represented by general formula (29) used in reaction formula 7 Some of these are known compounds, some of which are commercially available. Other than the above, general synthesis methods described in the literature, for example, Chemistry Letters [Chem. Lett.] 1976, 373 pages, Journal of the American Chemical Society [J. Am. Chem. Soc.] 1964, 86, 4383, The Journal of Organic Chemistry [J. Org. Chem.] 1976, 41, 4028 and 1978, 43, 3244, Organic Synthesis [Org. Synth.] 1988, Collective Volume 6, p. 101, Tetrahedron Lett. 1972, p. 4339, British Patent (GB 2,161,802), European Patent (EP 0,051,273), etc. It can be easily synthesized according to the method described in 1.

一般式(17)で表される化合物の或るものは公知化合物であり、一部は市販品として入手できる。また、それ以外のものも、例えば次のようにして合成できる。   Some of the compounds represented by the general formula (17) are known compounds, and some of them are commercially available. Others can be synthesized as follows, for example.

反応式１４   Reaction formula 14

Figure 2005126418
Figure 2005126418

すなわち、一般式(32)［式中、X及びmは前記と同じ意味を表し、Rはメチル基、エチル基等の低級アルキル基を表す。］で表される化合物を文献記載の一般的な加水分解反応、例えばアンゲバンテ・ヘミー[Angew. Chem.]１９５１年、６３巻、３２９頁、ジャーナル・オブ・ジ・アメリカン・ケミカル・ソサイエティー[J. Am. Chem. Soc.]１９２９年、５１巻、１８６５頁等に記載の方法に準じて一般式(33)［式中、X及びmは前記と同じ意味を表す。］で表されるフタル酸誘導体とした後、文献記載の一般的な脱水環化反応、例えばザ・ジャーナル・オブ・オーガニック・ケミストリー［J. Org. Chem.］１９８７年、５２巻、１２９頁等に記載の方法に準じた条件下反応させることにより、一般式(17)［式中、X及びmは前記と同じ意味を表す。］で表される化合物を得ることができる。   That is, in the general formula (32) [wherein X and m represent the same meaning as described above, and R represents a lower alkyl group such as a methyl group or an ethyl group. The compound represented by the general hydrolysis reaction described in the literature, for example, Angewante Chem. 1951, 63, 329, Journal of the American Chemical Society [J. Am. Chem. Soc.] 1929, 51, 1865, etc. In accordance with the general formula (33) [wherein X and m represent the same meaning as described above. ], Followed by a general dehydration cyclization reaction described in the literature, such as The Journal of Organic Chemistry [J. Org. Chem.] 1987, 52, 129, etc. In the general formula (17), wherein X and m are as defined above. The compound represented by this can be obtained.

ここで用いられる一般式(32)で表される化合物は公知化合物であり、一部は市販品として入手できる。   The compounds represented by the general formula (32) used here are known compounds, and some of them are available as commercial products.

一般式(18)で表される化合物は、例えば次のように合成できる。   The compound represented by the general formula (18) can be synthesized, for example, as follows.

反応式１５   Reaction formula 15

Figure 2005126418
Figure 2005126418

すなわち、公知の一般式(34)［式中、Y, R3, n及びPは前記と同じ意味を表す。］で表される化合物と公知の一般式(35)［式中、R4は前記と同じ意味を表し、J4はハロゲン原子、トリフルオロメタンスルホニルオキシ基、2-ピリジルオキシ基等の脱離基を表す。］で表される化合物又は公知の一般式(36)［式中、R4は前記と同じ意味を表す。］で表される化合物とを文献記載の一般的な芳香環のアシル化反応、例えばケミストリー・レターズ［Chem. Lett.］１９９０年、７８３頁、ザ・ジャーナル・オブ・オーガニック・ケミストリー［J. Org. Chem.］１９９１年、５６巻、１９６３頁等に記載の方法に準じて反応させることにより、一般式(18)［式中、Y, R3, R4, n及びPは前記と同じ意味を表す。］で表される化合物を得ることができる。 That is, the known general formula (34) [wherein Y, R 3 , n and P represent the same meaning as described above. And a known general formula (35) [wherein R 4 represents the same meaning as described above, and J 4 represents a leaving group such as a halogen atom, a trifluoromethanesulfonyloxy group, a 2-pyridyloxy group, or the like. Represents. ] Or a known general formula (36) [wherein R 4 represents the same meaning as described above. The general aromatic ring acylation reaction described in the literature, for example, Chemistry Letters [Chem. Lett.] 1990, p. 783, The Journal of Organic Chemistry [J. Org] Chem.] 1991, 56, 1963, etc., by reacting in accordance with the general formula (18) [wherein Y, R 3 , R 4 , n and P have the same meaning as described above. Represents. The compound represented by this can be obtained.

或いは、一般式(26)［式中、Y, R3, n, J2及びPは前記と同じ意味を表す。］で表される化合物を文献記載の一般的な方法、例えばリチオ化した後、公知の一般式(37)［式中、R4は前記と同じ意味を表し、J5はハロゲン原子、水酸基、金属塩（例えば、-OLi、-ONa）、C1〜C4アルコキシ基（例えば、メトキシ基、エトキシ基）、ジ(C1〜C4アルキル)アミノ基（例えば、ジエチルアミノ基）、C1〜C4アルコキシ(C1〜C4アルキル)アミノ基（例えば、O,N-ジメチルヒドロキシアミノ基）又は環状アミノ基（例えば、ピペリジン-1-イル基、モルホリン-4-イル基、4-メチルピペラジン-1-イル基）を表す。］で表される化合物又は公知の一般式(36)で表される化合物と反応させるジャーナル・オブ・ジ・アメリカン・ケミカル・ソサイエティー[J. Am. Chem. Soc.]１９５５年、７７巻、３６５７頁、テトラヘドロン・レターズ［Tetrahedron Lett.］１９８０年、２１巻、２１２９頁及び１９９１年、３２巻、２００３頁、アメリカ合衆国特許出願公報（US 5,514,816号公報）等に記載の方法、或いはグリニャール反応剤を形成した後、一般式(37)で表される化合物又は一般式(36)で表される化合物と反応させるヘテロサイクルズ［Heterocycles］１９８７年、２５巻、２２１頁、シンセティック・コミュニケーションズ［Synth. Commun.］１９８５年、１５巻、１２９１頁及び１９９０年、２０巻、１４６９頁、ドイツ国特許出願公報（DE 19727042号公報）等に記載の方法に準じて反応させることにより、一般式(18)で表される化合物を得ることもできる。 Alternatively, the general formula (26) [wherein Y, R 3 , n, J 2 and P represent the same meaning as described above. ], After lithiation of the compound represented by the literature, for example, known general formula (37) [wherein R 4 represents the same meaning as described above, J 5 represents a halogen atom, a hydroxyl group, metal salts (e.g., -OLi, -ONa), C 1 ~C 4 alkoxy group (e.g., methoxy group, ethoxy group), di (C 1 -C 4 alkyl) amino group (e.g., diethylamino group), C 1 ~ C 4 alkoxy (C 1 -C 4 alkyl) amino group (for example, O, N-dimethylhydroxyamino group) or cyclic amino group (for example, piperidin-1-yl group, morpholin-4-yl group, 4-methylpiperazine) -1-yl group). Or the known compound represented by the general formula (36) [J. Am. Chem. Soc.] 1955, 77, 3657 Tetrahedron Lett. 1980, 21, 2129 and 1991, 32, 2003, US Patent Application Publication (US 5,514,816), etc., or Grignard reactant Heterocycles 1987, 25, 221, Synthetic Communications [Synth. Communication, which is formed and then reacted with a compound represented by general formula (37) or a compound represented by general formula (36) In accordance with the method described in 1985, 15, 1291 and 1990, 20, 1469, German Patent Application Publication (DE 19727042), etc. To obtain a compound represented by the general formula (18).

一般式(21)で表される化合物は一般式(18)で表される化合物と同様に合成することができる。   The compound represented by the general formula (21) can be synthesized in the same manner as the compound represented by the general formula (18).

一般式(26)で表される化合物は、例えば次のように合成できる。   The compound represented by the general formula (26) can be synthesized, for example, as follows.

反応式１６   Reaction formula 16

Figure 2005126418
Figure 2005126418

すなわち、公知の一般式(38)［式中、Y, R3, n及びJ2は前記と同じ意味を表す。］で表される置換アニリンを文献記載の一般的な方法、例えばジャーナル・オブ・メディシナル・ケミストリー［J. Med. Chem.］１９９６年、３９巻、６７３頁及び１９９７年、４０巻、３５４２頁等に記載の方法に準じてアミノ基を保護することにより、一般式(26)［式中、Y, R3, n, J2及びPは前記と同じ意味を表す。］で表される化合物を得ることができる。 That is, the known general formula (38) [wherein Y, R 3 , n and J 2 represent the same meaning as described above. The substituted aniline represented by the general method described in the literature, for example, Journal of Medicinal Chemistry [J. Med. Chem.] 1996, 39, 673 and 1997, 40, 3542, etc. In the general formula (26), Y, R 3 , n, J 2 and P have the same meaning as described above. The compound represented by this can be obtained.

一般式(27)で表される化合物の或るものは公知化合物であり、一部は市販品として入手できる。また、それ以外のものも一般式(18)で表される化合物と同様に合成することができる。   Some of the compounds represented by the general formula (27) are known compounds, and some of them are commercially available. Other compounds can be synthesized in the same manner as the compound represented by the general formula (18).

これらの各反応においては、反応終了後、通常の後処理を行なうことにより製造法A〜製造法Iの原料化合物となる各々の製造中間体を得ることができる。   In each of these reactions, after the completion of the reaction, each of the production intermediates that are the raw material compounds of Production Method A to Production Method I can be obtained by performing a general post-treatment.

また、これらの方法により製造された各々の製造中間体は、単離・精製することなく、それぞれそのまま次工程の反応に用いることもできる。   In addition, each production intermediate produced by these methods can be used as it is in the subsequent step without isolation and purification.

本発明に包含される化合物としては、具体的に例えば、第２表〜第５表に示す化合物が挙げられる。但し、第２表〜第５表の化合物は例示のためのものであって、本発明はこれらのみに限定されるものではない。   Specific examples of the compound included in the present invention include compounds shown in Tables 2 to 5. However, the compounds in Tables 2 to 5 are for illustrative purposes, and the present invention is not limited thereto.

尚、表中Etとの記載はエチル基を表し、以下同様にn-Pr及びPr-nはノルマルプロピル基を、i-Pr及びPr-iはイソプロピル基を、c-Pr及びPr-cはシクロプロピル基を、n-Bu及びBu-nはノルマルブチル基を、s-Bu及びBu-sはセカンダリーブチル基を、i-Bu及びBu-iはイソブチル基を、t-Bu及びBu-tはターシャリーブチル基を、c-Bu及びBu-cはシクロブチル基を、n-Pen及びPen-nはノルマルペンチル基を、c-Pen及びPen-cはシクロペンチル基を、n-Hex及びHex-nはノルマルヘキシル基を、c-Hex及びHex-cはシクロヘキシル基を、Octはオクチル基を、Phはフェニル基を、1-Naphは1-ナフチル基を、2-Naphは2-ナフチル基をそれぞれ表し、
表中L-1a〜L-55aで表される芳香族複素環は、それぞれ下記の構造を表し、 In the table, “Et” represents an ethyl group. Similarly, n-Pr and Pr-n are normal propyl groups, i-Pr and Pr-i are isopropyl groups, and c-Pr and Pr-c are Cyclopropyl group, n-Bu and Bu-n are normal butyl groups, s-Bu and Bu-s are secondary butyl groups, i-Bu and Bu-i are isobutyl groups, t-Bu and Bu-t Is a tertiary butyl group, c-Bu and Bu-c are cyclobutyl groups, n-Pen and Pen-n are normal pentyl groups, c-Pen and Pen-c are cyclopentyl groups, n-Hex and Hex- n is a normal hexyl group, c-Hex and Hex-c are cyclohexyl groups, Oct is an octyl group, Ph is a phenyl group, 1-Naph is a 1-naphthyl group, 2-Naph is a 2-naphthyl group. Respectively,
The aromatic heterocycles represented by L-1a to L-55a in the table each represent the following structure,

Figure 2005126418
Figure 2005126418

Figure 2005126418
Figure 2005126418

Figure 2005126418
Figure 2005126418

例えば、(L-16a)CHF２の表記は、1-ジフルオロメチルピラゾール-4-イル基を表し、(L-45c)CF３の表記は、5-トリフルオロメチルピリジン-2-イル基を表す。 For example, the notation of (L-16a) CHF 2 represents a 1-difluoromethylpyrazol-4-yl group, and the notation of (L-45c) CF 3 represents a 5-trifluoromethylpyridin-2-yl group .

表中M-4a〜M-22aで表される脂肪族複素環は、それぞれ下記の構造を表し、   The aliphatic heterocycles represented by M-4a to M-22a in the table each represent the following structure,

Figure 2005126418
Figure 2005126418

例えば、(M-22a)C(O)OCH3の表記は、1-メトキシカルボニルピペリジン-4-イル基を表す。 For example, the notation (M-22a) C (O) OCH 3 represents a 1-methoxycarbonylpiperidin-4-yl group.

さらに、表中T-1〜T-24は、それぞれ下記の構造を表す。   Further, T-1 to T-24 in the table each represent the following structure.

Figure 2005126418
Figure 2005126418

第２表 Table 2

Figure 2005126418
Figure 2005126418

Figure 2005126418
Figure 2005126418

Figure 2005126418
Figure 2005126418

Figure 2005126418
Figure 2005126418

―――――――――――――――――――――――――――――――――――――――
R2 R1 R4 R5
―――――――――――――――――――――――――――――――――――――――
H CH3 CF3 CF2O(Ph-4-Cl)
H CH3 CF3 CH=CH(Ph-4-Cl)
H CH3 CF3 CH=CH(Ph-4-OCF3)
H CH3 CF3 CH=CH(Ph-3,4-Cl2)
H CH3 CF3 Ph-4-F
H CH3 CF3 Ph-4-Cl
H CH3 CF3 Ph-4-Br
H CH3 CF3 Ph-4-I
H CH3 CF3 Ph-4-CF3
H CH3 CF3 Ph-4-OCHF2
H CH3 CF3 Ph-4-OCF3
H CH3 CF3 Ph-4-OCF2Br
H CH3 CF3 Ph-4-OCF2CHF2
H CH3 CF3 Ph-4-OCF2CHFCl
H CH3 CF3 Ph-4-OCF2CHFCF3
H CH3 CF3 Ph-4-OCF2CHFOCF3
H CH3 CF3 Ph-4-OCF2CHFOCF2CF2CF3
H CH3 CF3 Ph-4-O(L-45e)
H CH3 CF3 Ph-3,4-Cl2
H CH3 CF3 Ph(-3-OCF2O-4-)
H CH3 CF3 Ph(-3-OCF2CF2O-4-)
H CH3 CF3 (L-45c)Cl
H CH3 CF3 (L-45c)Br
H CH3 CF3 (L-45c)CF3
H CH3 CF3 L-45e
H CH3 CF3 L-45f
H CH3 CF3 (L-46c)Cl
H CH3 CF3 (L-46c)Br
H CH3 CF3 (L-46c)CF3
H CH3 CF3 L-46d
CH3 CH3 CF3 Ph-4-Br
CH3 CH3 CF3 Ph-4-CF3
CH3 CH3 CF3 Ph-4-OCF3
CH3 CH3 CF3 (L-45c)CF3
H Et CH3 Ph-4-Cl
H Et CH3 Ph-4-CF3
H Et CH3 Ph-4-OCF3
H Et CH3 (L-45c)Cl
H Et CH3 (L-45c)Br
H Et CH3 (L-45c)CF3
H Et Et Ph-4-Br
H Et n-Pr Ph-4-CF3
H Et i-Pr Ph-4-OCF3
H Et c-Pr (L-45c)CF3
H Et CHF2 Ph-4-Br
H Et CF3 CF2O(Ph-4-Cl)
H Et CF3 CH=CH(Ph-4-Cl)
H Et CF3 CH=CH(Ph-4-OCF3)
H Et CF3 CH=CH(Ph-3,4-Cl2)
H Et CF3 Ph-4-F
H Et CF3 Ph-4-Cl
H Et CF3 Ph-4-Br
H Et CF3 Ph-4-I
H Et CF3 Ph-4-CF3
H Et CF3 Ph-4-OCHF2
H Et CF3 Ph-4-OCF3
H Et CF3 Ph-4-OCF2Br
H Et CF3 Ph-4-OCF2CHF2
H Et CF3 Ph-4-OCF2CHFCl
H Et CF3 Ph-4-OCF2CHFCF3
H Et CF3 Ph-4-OCF2CHFOCF3
H Et CF3 Ph-4-OCF2CHFOCF2CF2CF3
H Et CF3 Ph-4-O(L-45g)
H Et CF3 Ph-3,4-Cl2
H Et CF3 Ph(-3-OCF2O-4-)
H Et CF3 Ph(-3-OCF2CF2O-4-)
H Et CF3 (L-45c)Cl
H Et CF3 (L-45c)Br
H Et CF3 (L-45c)CF3
H Et CF3 L-45e
H Et CF3 L-45f
H Et CF3 (L-46c)Cl
H Et CF3 (L-46c)Br
H Et CF3 (L-46c)CF3
H Et CF3 L-46d
H Et CF2Cl Ph-4-CF3
H Et CF2Br Ph-4-OCF3
H Et CF2CF3 (L-45c)CF3
H Et CF2CF2CF3 Ph-4-Br
H Et CF2OCH3 Ph-4-CF3
H Et CF2SCH3 Ph-4-OCF3
Et Et CH3 Ph-4-Br
Et Et CH3 Ph-4-CF3
Et Et CH3 Ph-4-OCF3
Et Et CH3 (L-45c)Cl
Et Et CH3 (L-45c)Br
Et Et CH3 (L-45c)CF3
Et Et CF3 CF2O(Ph-4-Cl)
Et Et CF3 CH=CH(Ph-4-Cl)
Et Et CF3 CH=CH(Ph-4-OCF3)
Et Et CF3 CH=CH(Ph-3,4-Cl2)
Et Et CF3 Ph-4-F
Et Et CF3 Ph-4-Cl
Et Et CF3 Ph-4-Br
Et Et CF3 Ph-4-I
Et Et CF3 Ph-4-CF3
Et Et CF3 Ph-4-OCHF2
Et Et CF3 Ph-4-OCF3
Et Et CF3 Ph-4-OCF2Br
Et Et CF3 Ph-4-OCF2CHF2
Et Et CF3 Ph-4-OCF2CHFCl
Et Et CF3 Ph-4-OCF2CHFCF3
Et Et CF3 Ph-4-OCF2CHFOCF3
Et Et CF3 Ph-4-OCF2CHFOCF2CF2CF3
Et Et CF3 Ph-4-O(L-45g)
Et Et CF3 Ph-3,4-Cl2
Et Et CF3 Ph(-3-OCF2O-4-)
Et Et CF3 Ph(-3-OCF2CF2O-4-)
Et Et CF3 (L-45c)Cl
Et Et CF3 (L-45c)Br
Et Et CF3 (L-45c)CF3
Et Et CF3 L-45e
Et Et CF3 L-45f
Et Et CF3 (L-46c)Cl
Et Et CF3 (L-46c)Br
Et Et CF3 (L-46c)CF3
Et Et CF3 L-46d
H n-Pr CH3 Ph-4-Br
H n-Pr CH3 Ph-4-CF3
H n-Pr CH3 Ph-4-OCF3
H n-Pr CH3 (L-45c)Cl
H n-Pr CH3 (L-45c)Br
H n-Pr CH3 (L-45c)CF3
H n-Pr Et (L-45c)CF3
H n-Pr n-Pr Ph-4-Br
H n-Pr i-Pr Ph-4-CF3
H n-Pr c-Pr Ph-4-OCF3
H n-Pr CHF2 (L-45c)CF3
H n-Pr CF3 CF2O(Ph-4-Cl)
H n-Pr CF3 CH=CH(Ph-4-Cl)
H n-Pr CF3 CH=CH(Ph-4-OCF3)
H n-Pr CF3 CH=CH(Ph-3,4-Cl2)
H n-Pr CF3 Ph-4-F
H n-Pr CF3 Ph-4-Cl
H n-Pr CF3 Ph-4-Br
H n-Pr CF3 Ph-4-I
H n-Pr CF3 Ph-4-CF3
H n-Pr CF3 Ph-4-OCHF2
H n-Pr CF3 Ph-4-OCF3
H n-Pr CF3 Ph-4-OCF2Br
H n-Pr CF3 Ph-4-OCF2CHF2
H n-Pr CF3 Ph-4-OCF2CHFCl
H n-Pr CF3 Ph-4-OCF2CHFCF3
H n-Pr CF3 Ph-4-OCF2CHFOCF3
H n-Pr CF3 Ph-4-OCF2CHFOCF2CF2CF3
H n-Pr CF3 Ph-4-O(L-45g)
H n-Pr CF3 Ph-3,4-Cl2
H n-Pr CF3 Ph(-3-OCF2O-4-)
H n-Pr CF3 Ph(-3-OCF2CF2O-4-)
H n-Pr CF3 (L-45c)Cl
H n-Pr CF3 (L-45c)Br
H n-Pr CF3 (L-45c)CF3
H n-Pr CF3 L-45e
H n-Pr CF3 L-45f
H n-Pr CF3 (L-46c)Cl
H n-Pr CF3 (L-46c)Br
H n-Pr CF3 (L-46c)CF3
H n-Pr CF3 L-46d
H n-Pr CF2Cl Ph-4-Br
H n-Pr CF2Br Ph-4-CF3
H n-Pr CF2CF3 Ph-4-OCF3
H n-Pr CF2CF2CF3 (L-45c)CF3
H n-Pr CF2OCH3 Ph-4-Br
H n-Pr CF2SCH3 Ph-4-CF3
CH3 n-Pr CF3 Ph-4-Br
CH3 n-Pr CF3 Ph-4-CF3
CH3 n-Pr CF3 Ph-4-OCF3
CH3 n-Pr CF3 (L-45c)CF3
Et n-Pr CF3 Ph-4-OCF3
n-Pr n-Pr CF3 (L-45c)CF3
H i-Pr CH3 CF2O(Ph-4-Cl)
H i-Pr CH3 CH=CH(Ph-4-Cl)
H i-Pr CH3 CH=CH(Ph-4-OCF3)
H i-Pr CH3 CH=CH(Ph-3,4-Cl2)
H i-Pr CH3 Ph-4-F
H i-Pr CH3 Ph-4-Cl
H i-Pr CH3 Ph-4-Br
H i-Pr CH3 Ph-4-I
H i-Pr CH3 Ph-4-CF3
H i-Pr CH3 Ph-4-OCHF2
H i-Pr CH3 Ph-4-OCF3
H i-Pr CH3 Ph-4-OCF2Br
H i-Pr CH3 Ph-4-OCF2CHF2
H i-Pr CH3 Ph-4-OCF2CHFCl
H i-Pr CH3 Ph-4-OCF2CHFCF3
H i-Pr CH3 Ph-4-OCF2CHFOCF3
H i-Pr CH3 Ph-4-OCF2CHFOCF2CF2CF3
H i-Pr CH3 Ph-4-O(L-45g)
H i-Pr CH3 Ph-3,4-Cl2
H i-Pr CH3 Ph(-3-OCF2O-4-)
H i-Pr CH3 Ph(-3-OCF2CF2O-4-)
H i-Pr CH3 (L-45c)Cl
H i-Pr CH3 (L-45c)Br
H i-Pr CH3 (L-45c)CF3
H i-Pr CH3 L-45e
H i-Pr CH3 L-45f
H i-Pr CH3 (L-46c)Cl
H i-Pr CH3 (L-46c)Br
H i-Pr CH3 (L-46c)CF3
H i-Pr CH3 L-46d
H i-Pr Et CF2O(Ph-4-Cl)
H i-Pr Et CH=CH(Ph-4-Cl)
H i-Pr Et CH=CH(Ph-4-OCF3)
H i-Pr Et CH=CH(Ph-3,4-Cl2)
H i-Pr Et Ph-4-Cl
H i-Pr Et Ph-4-Br
H i-Pr Et Ph-4-CF3
H i-Pr Et Ph-4-OCF3
H i-Pr Et Ph-4-OCF2Br
H i-Pr Et Ph-4-OCF2CHFCF3
H i-Pr Et Ph-4-OCF2CHFOCF3
H i-Pr Et Ph-4-OCF2CHFOCF2CF2CF3
H i-Pr Et Ph-4-O(L-45g)
H i-Pr Et Ph-3,4-Cl2
H i-Pr Et Ph(-3-OCF2O-4-)
H i-Pr Et Ph(-3-OCF2CF2O-4-)
H i-Pr Et (L-45c)Br
H i-Pr Et (L-45c)CF3
H i-Pr Et L-45e
H i-Pr Et L-45f
H i-Pr Et (L-46c)Br
H i-Pr Et (L-46c)CF3
H i-Pr Et L-46d
H i-Pr n-Pr CF2O(Ph-4-Cl)
H i-Pr n-Pr CH=CH(Ph-4-Cl)
H i-Pr n-Pr CH=CH(Ph-4-OCF3)
H i-Pr n-Pr CH=CH(Ph-3,4-Cl2)
H i-Pr n-Pr Ph-4-Cl
H i-Pr n-Pr Ph-4-Br
H i-Pr n-Pr Ph-4-CF3
H i-Pr n-Pr Ph-4-OCF3
H i-Pr n-Pr Ph-4-OCF2Br
H i-Pr n-Pr Ph-4-OCF2CHFCF3
H i-Pr n-Pr Ph-4-OCF2CHFOCF3
H i-Pr n-Pr Ph-4-OCF2CHFOCF2CF2CF3
H i-Pr n-Pr Ph-4-O(L-45g)
H i-Pr n-Pr Ph-3,4-Cl2
H i-Pr n-Pr Ph(-3-OCF2O-4-)
H i-Pr n-Pr Ph(-3-OCF2CF2O-4-)
H i-Pr n-Pr (L-45c)Br
H i-Pr n-Pr (L-45c)CF3
H i-Pr n-Pr L-45e
H i-Pr n-Pr L-45f
H i-Pr n-Pr (L-46c)Br
H i-Pr n-Pr (L-46c)CF3
H i-Pr n-Pr L-46d
H i-Pr i-Pr CF2O(Ph-4-Cl)
H i-Pr i-Pr CH=CH(Ph-4-Cl)
H i-Pr i-Pr CH=CH(Ph-4-OCF3)
H i-Pr i-Pr CH=CH(Ph-3,4-Cl2)
H i-Pr i-Pr Ph-4-Cl
H i-Pr i-Pr Ph-4-Br
H i-Pr i-Pr Ph-4-CF3
H i-Pr i-Pr Ph-4-OCF3
H i-Pr i-Pr Ph-4-OCF2Br
H i-Pr i-Pr Ph-4-OCF2CHFCF3
H i-Pr i-Pr Ph-4-OCF2CHFOCF3
H i-Pr i-Pr Ph-4-OCF2CHFOCF2CF2CF3
H i-Pr i-Pr Ph-4-O(L-45g)
H i-Pr i-Pr Ph-3,4-Cl2
H i-Pr i-Pr Ph(-3-OCF2O-4-)
H i-Pr i-Pr Ph(-3-OCF2CF2O-4-)
H i-Pr i-Pr (L-45c)Br
H i-Pr i-Pr (L-45c)CF3
H i-Pr i-Pr L-45e
H i-Pr i-Pr L-45f
H i-Pr i-Pr (L-46c)Br
H i-Pr i-Pr (L-46c)CF3
H i-Pr i-Pr L-46d
H i-Pr c-Pr CF2O(Ph-4-Cl)
H i-Pr c-Pr CH=CH(Ph-4-Cl)
H i-Pr c-Pr CH=CH(Ph-4-OCF3)
H i-Pr c-Pr CH=CH(Ph-3,4-Cl2)
H i-Pr c-Pr Ph-4-Cl
H i-Pr c-Pr Ph-4-Br
H i-Pr c-Pr Ph-4-CF3
H i-Pr c-Pr Ph-4-OCF3
H i-Pr c-Pr Ph-4-OCF2Br
H i-Pr c-Pr Ph-4-OCF2CHFCF3
H i-Pr c-Pr Ph-4-OCF2CHFOCF3
H i-Pr c-Pr Ph-4-OCF2CHFOCF2CF2CF3
H i-Pr c-Pr Ph-4-O(L-45g)
H i-Pr c-Pr Ph-3,4-Cl2
H i-Pr c-Pr Ph(-3-OCF2O-4-)
H i-Pr c-Pr Ph(-3-OCF2CF2O-4-)
H i-Pr c-Pr (L-45c)Br
H i-Pr c-Pr (L-45c)CF3
H i-Pr c-Pr L-45e
H i-Pr c-Pr L-45f
H i-Pr c-Pr (L-46c)Br
H i-Pr c-Pr (L-46c)CF3
H i-Pr c-Pr L-46d
H i-Pr n-Bu Ph-4-Br
H i-Pr s-Bu Ph-4-CF3
H i-Pr i-Bu Ph-4-OCF3
H i-Pr c-Bu (L-45c)CF3
H i-Pr n-Pen Ph-4-Br
H i-Pr c-Pen Ph-4-CF3
H i-Pr n-Hex Ph-4-OCF3
H i-Pr c-Hex (L-45c)CF3
H i-Pr CH2F Ph-4-Br
H i-Pr CH2Cl Ph-4-CF3
H i-Pr CH2Br Ph-4-OCF3
H i-Pr CHF2 CF2O(Ph-4-Cl)
H i-Pr CHF2 CH=CH(Ph-4-Cl)
H i-Pr CHF2 CH=CH(Ph-4-OCF3)
H i-Pr CHF2 CH=CH(Ph-3,4-Cl2)
H i-Pr CHF2 Ph-4-F
H i-Pr CHF2 Ph-4-Cl
H i-Pr CHF2 Ph-4-Br
H i-Pr CHF2 Ph-4-I
H i-Pr CHF2 Ph-4-CF3
H i-Pr CHF2 Ph-4-OCHF2
H i-Pr CHF2 Ph-4-OCF3
H i-Pr CHF2 Ph-4-OCF2Br
H i-Pr CHF2 Ph-4-OCF2CHF2
H i-Pr CHF2 Ph-4-OCF2CHFCl
H i-Pr CHF2 Ph-4-OCF2CHFCF3
H i-Pr CHF2 Ph-4-OCF2CHFOCF3
H i-Pr CHF2 Ph-4-OCF2CHFOCF2CF2CF3
H i-Pr CHF2 Ph-4-O(L-45g)
H i-Pr CHF2 Ph-3,4-Cl2
H i-Pr CHF2 Ph(-3-OCF2O-4-)
H i-Pr CHF2 Ph(-3-OCF2CF2O-4-)
H i-Pr CHF2 (L-45c)Cl
H i-Pr CHF2 (L-45c)Br
H i-Pr CHF2 (L-45c)CF3
H i-Pr CHF2 L-45e
H i-Pr CHF2 L-45f
H i-Pr CHF2 (L-46c)Cl
H i-Pr CHF2 (L-46c)Br
H i-Pr CHF2 (L-46c)CF3
H i-Pr CHF2 L-46d
H i-Pr CHFCl (L-45c)CF3
H i-Pr CHFBr Ph-4-Br
H i-Pr CF3 T-1
H i-Pr CF3 T-2
H i-Pr CF3 T-3
H i-Pr CF3 T-4
H i-Pr CF3 T-5
H i-Pr CF3 CH2OCH3
H i-Pr CF3 CH2OEt
H i-Pr CF3 CH2OPr-n
H i-Pr CF3 CH2OPr-i
H i-Pr CF3 CH2OBu-n
H i-Pr CF3 CH2OCH2CF3
H i-Pr CF3 CH2OCH2CF2CF3
H i-Pr CF3 CH2OCH(CF3)2
H i-Pr CF3 CH2OC(O)(Ph-2-Cl)
H i-Pr CF3 CH2OC(O)(Ph-3-Cl)
H i-Pr CF3 CH2OC(O)(Ph-4-Cl)
H i-Pr CF3 CH2OPh
H i-Pr CF3 CH2O(Ph-4-F)
H i-Pr CF3 CH2O(Ph-2-Cl)
H i-Pr CF3 CH2O(Ph-3-Cl)
H i-Pr CF3 CH2O(Ph-4-Cl)
H i-Pr CF3 CH2O(Ph-4-Br)
H i-Pr CF3 CH2O(Ph-4-CF3)
H i-Pr CF3 CH2O(Ph-4-OCF3)
H i-Pr CF3 CH2CH2OCH3
H i-Pr CF3 CF2OPh
H i-Pr CF3 CF2O(Ph-3-F)
H i-Pr CF3 CF2O(Ph-4-F)
H i-Pr CF3 CF2O(Ph-2-Cl)
H i-Pr CF3 CF2O(Ph-3-Cl)
H i-Pr CF3 CF2O(Ph-4-Cl)
H i-Pr CF3 CF2O(Ph-3-Br)
H i-Pr CF3 CF2O(Ph-4-Br)
H i-Pr CF3 CF2O(Ph-3-CF3)
H i-Pr CF3 CF2O(Ph-4-CF3)
H i-Pr CF3 CF2O(Ph-3-OCF3)
H i-Pr CF3 CF2O(Ph-4-OCF3)
H i-Pr CF3 M-4a
H i-Pr CF3 M-5a
H i-Pr CF3 CH2SCH3
H i-Pr CF3 CH2SO2CH3
H i-Pr CF3 CH2SCF3
H i-Pr CF3 CH2SO2CF3
H i-Pr CF3 CH2SPh
H i-Pr CF3 CH2S(Ph-3-Cl)
H i-Pr CF3 CH2S(Ph-4-Cl)
H i-Pr CF3 CH2SO2(Ph-3-Cl)
H i-Pr CF3 CH2SO2(Ph-4-Cl)
H i-Pr CF3 CH2CH2SCH3
H i-Pr CF3 CH2CH2SO2CH3
H i-Pr CF3 CH2CH(CH3)SCH3
H i-Pr CF3 CH2CH(CH3)SEt
H i-Pr CF3 CH2CH2SCF3
H i-Pr CF3 CH2N(CH3)2
H i-Pr CF3 CH2NHPh
H i-Pr CF3 CH2NH(Ph-3-Cl)
H i-Pr CF3 CH2NH(Ph-4-Cl)
H i-Pr CF3 CF2C(O)OEt
H i-Pr CF3 CH2CH2Ph
H i-Pr CF3 CH2CH2(Ph-3-Cl)
H i-Pr CF3 CH2CH2(Ph-4-Cl)
H i-Pr CF3 CH(CH3)CH2Ph
H i-Pr CF3 CH2(L-5a)
H i-Pr CF3 CH2(L-14a)
H i-Pr CF3 CH2(L-24a)
H i-Pr CF3 CH2(L-36a)
H i-Pr CF3 T-22
H i-Pr CF3 T-23
H i-Pr CF3 T-24
H i-Pr CF3 C(O)OCH3
H i-Pr CF3 C(O)OEt
H i-Pr CF3 C(O)OPr-n
H i-Pr CF3 C(O)OPr-i
H i-Pr CF3 C(O)OBu-n
H i-Pr CF3 C(O)OBu-t
H i-Pr CF3 C(O)OCH2CF3
H i-Pr CF3 C(O)SEt
H i-Pr CF3 C(O)N(CH3)2
H i-Pr CF3 CH=CHPh
H i-Pr CF3 CH=CH(Ph-3-F)
H i-Pr CF3 CH=CH(Ph-4-F)
H i-Pr CF3 CH=CH(Ph-2-Cl)
H i-Pr CF3 CH=CH(Ph-3-Cl)
H i-Pr CF3 CH=CH(Ph-4-Cl)
H i-Pr CF3 CH=CH(Ph-3-Br)
H i-Pr CF3 CH=CH(Ph-4-Br)
H i-Pr CF3 CH=CH(Ph-3-CF3)
H i-Pr CF3 CH=CH(Ph-4-CF3)
H i-Pr CF3 CH=CH(Ph-3-OCF3)
H i-Pr CF3 CH=CH(Ph-4-OCF3)
H i-Pr CF3 CH=CH(Ph-3-SCH3)
H i-Pr CF3 CH=CH(Ph-4-SCH3)
H i-Pr CF3 CH=CH(Ph-3-SO2CH3)
H i-Pr CF3 CH=CH(Ph-4-SO2CH3)
H i-Pr CF3 CH=CH(Ph-3,4-F2)
H i-Pr CF3 CH=CH(Ph-3-F-4-Cl)
H i-Pr CF3 CH=CH(Ph-3,4-Cl2)
H i-Pr CF3 CH=CH(Ph-3,4-Br2)
H i-Pr CF3 CH=CH(Ph-3-F-4-CF3)
H i-Pr CF3 CH=CH(Ph-3-Cl-4-OCF3)
H i-Pr CF3 CH=CH[Ph(-3-OCF2O-4-)]
H i-Pr CF3 Ph
H i-Pr CF3 Ph-3-F
H i-Pr CF3 Ph-4-F
H i-Pr CF3 Ph-2-Cl
H i-Pr CF3 Ph-3-Cl
H i-Pr CF3 Ph-4-Cl
H i-Pr CF3 Ph-3-Br
H i-Pr CF3 Ph-4-Br
H i-Pr CF3 Ph-3-I
H i-Pr CF3 Ph-4-I
H i-Pr CF3 Ph-4-CH3
H i-Pr CF3 Ph-4-Et
H i-Pr CF3 Ph-4-Pr-n
H i-Pr CF3 Ph-4-Pr-i
H i-Pr CF3 Ph-4-Bu-n
H i-Pr CF3 Ph-4-Bu-i
H i-Pr CF3 Ph-4-Bu-t
H i-Pr CF3 Ph-3-CF3
H i-Pr CF3 Ph-4-CF3
H i-Pr CF3 Ph-4-C(CF3)2OH
H i-Pr CF3 Ph-4-C(CF3)2OCH3
H i-Pr CF3 Ph-4-CH2OCH3
H i-Pr CF3 Ph-4-CH2OCH2CF3
H i-Pr CF3 Ph-4-CH2SCH3
H i-Pr CF3 Ph-4-CH2S(O)CH3
H i-Pr CF3 Ph-4-CH2SO2CH3
H i-Pr CF3 Ph-4-CH2SEt
H i-Pr CF3 Ph-4-CH2S(O)Et
H i-Pr CF3 Ph-4-CH2SO2Et
H i-Pr CF3 Ph-4-CH2SPr-n
H i-Pr CF3 Ph-4-CH2SO2Pr-n
H i-Pr CF3 Ph-4-CH2SPr-i
H i-Pr CF3 Ph-4-CH2SO2Pr-i
H i-Pr CF3 Ph-4-CH2SPr-c
H i-Pr CF3 Ph-4-CH2SO2Pr-c
H i-Pr CF3 Ph-4-CH2SBu-n
H i-Pr CF3 Ph-4-CH2SO2Bu-n
H i-Pr CF3 Ph-4-CH2SCF3
H i-Pr CF3 Ph-4-CH2S(O)CF3
H i-Pr CF3 Ph-4-CH2SO2CF3
H i-Pr CF3 Ph-4-CH2SCH2CF3
H i-Pr CF3 Ph-4-OH
H i-Pr CF3 Ph-4-OCH3
H i-Pr CF3 Ph-4-OEt
H i-Pr CF3 Ph-4-OPr-n
H i-Pr CF3 Ph-4-OPr-i
H i-Pr CF3 Ph-4-OBu-n
H i-Pr CF3 Ph-4-OBu-t
H i-Pr CF3 Ph-4-OCHF2
H i-Pr CF3 Ph-3-OCF3
H i-Pr CF3 Ph-4-OCF3
H i-Pr CF3 Ph-4-OCF2Br
H i-Pr CF3 Ph-4-OCH2CF3
H i-Pr CF3 Ph-4-OCF2CHF2
H i-Pr CF3 Ph-4-OCF2CHFCl
H i-Pr CF3 Ph-4-OCF2CHFBr
H i-Pr CF3 Ph-4-OCF2CF2Br
H i-Pr CF3 Ph-4-OCF2CFCl2
H i-Pr CF3 Ph-4-OCF2CCl3
H i-Pr CF3 Ph-4-OCH2CF2CHF2
H i-Pr CF3 Ph-3-OCF2CHFCF3
H i-Pr CF3 Ph-4-OCF2CHFCF3
H i-Pr CF3 Ph-4-OCH(CF3)2
H i-Pr CF3 Ph-4-OCF2CFBrCF3
H i-Pr CF3 Ph-3-OCF2CHFOCF3
H i-Pr CF3 Ph-4-OCF2CHFOCF3
H i-Pr CF3 Ph-4-OCF2CHFOCF2CF2CF3
H i-Pr CF3 Ph-4-OCH2CH=CH2
H i-Pr CF3 Ph-4-OCH2CH=CF2
H i-Pr CF3 Ph-4-OCH2CF=CF2
H i-Pr CF3 Ph-4-OCH2CH=CCl2
H i-Pr CF3 Ph-4-OCH2CCl=CCl2
H i-Pr CF3 Ph-4-OCH2Ph
H i-Pr CF3 Ph-4-OSO2CH3
H i-Pr CF3 Ph-4-OSO2Et
H i-Pr CF3 Ph-4-OSO2Pr-n
H i-Pr CF3 Ph-4-OSO2Pr-i
H i-Pr CF3 Ph-4-OSO2Bu-n
H i-Pr CF3 Ph-4-OSO2CHCl2
H i-Pr CF3 Ph-4-OSO2CF3
H i-Pr CF3 Ph-4-OSO2CH2CF3
H i-Pr CF3 Ph-3-O(Ph-4-Cl)
H i-Pr CF3 Ph-4-O(Ph-4-Cl)
H i-Pr CF3 Ph-4-O(Ph-4-Br)
H i-Pr CF3 Ph-4-O(Ph-4-CF3)
H i-Pr CF3 Ph-4-O(L-21b)Br
H i-Pr CF3 Ph-4-O(L-21b)CF3
H i-Pr CF3 Ph-3-O(L-45c)Br
H i-Pr CF3 Ph-4-O(L-45c)Br
H i-Pr CF3 Ph-3-O(L-45c)CF3
H i-Pr CF3 Ph-4-O(L-45c)CF3
H i-Pr CF3 Ph-3-O(L-45e)
H i-Pr CF3 Ph-4-O(L-45e)
H i-Pr CF3 Ph-3-O(L-48b)Br
H i-Pr CF3 Ph-4-O(L-48b)Br
H i-Pr CF3 Ph-4-SCH3
H i-Pr CF3 Ph-4-S(O)CH3
H i-Pr CF3 Ph-4-SO2CH3
H i-Pr CF3 Ph-4-SEt
H i-Pr CF3 Ph-4-S(O)Et
H i-Pr CF3 Ph-4-SO2Et
H i-Pr CF3 Ph-4-SPr-n
H i-Pr CF3 Ph-4-S(O)Pr-n
H i-Pr CF3 Ph-4-SO2Pr-n
H i-Pr CF3 Ph-4-SPr-i
H i-Pr CF3 Ph-4-S(O)Pr-i
H i-Pr CF3 Ph-4-SO2Pr-i
H i-Pr CF3 Ph-4-SBu-n
H i-Pr CF3 Ph-4-S(O)Bu-n
H i-Pr CF3 Ph-4-SO2Bu-n
H i-Pr CF3 Ph-4-SBu-t
H i-Pr CF3 Ph-4-S(O)Bu-t
H i-Pr CF3 Ph-4-SO2Bu-t
H i-Pr CF3 Ph-4-SCH2F
H i-Pr CF3 Ph-4-S(O)CH2F
H i-Pr CF3 Ph-4-SO2CH2F
H i-Pr CF3 Ph-4-SCHF2
H i-Pr CF3 Ph-4-S(O)CHF2
H i-Pr CF3 Ph-4-SO2CHF2
H i-Pr CF3 Ph-3-SCF3
H i-Pr CF3 Ph-4-SCF3
H i-Pr CF3 Ph-4-S(O)CF3
H i-Pr CF3 Ph-4-SO2CF3
H i-Pr CF3 Ph-4-SCF2Cl
H i-Pr CF3 Ph-4-S(O)CF2Cl
H i-Pr CF3 Ph-4-SO2CF2Cl
H i-Pr CF3 Ph-4-SCF2Br
H i-Pr CF3 Ph-4-S(O)CF2Br
H i-Pr CF3 Ph-4-SO2CF2Br
H i-Pr CF3 Ph-3-S(Ph-4-Cl)
H i-Pr CF3 Ph-4-S(Ph-4-Cl)
H i-Pr CF3 Ph-4-S(Ph-4-Br)
H i-Pr CF3 Ph-4-S(Ph-4-CF3)
H i-Pr CF3 Ph-4-S(L-45c)Br
H i-Pr CF3 Ph-4-S(L-45c)CF3
H i-Pr CF3 Ph-4-S(L-45e)
H i-Pr CF3 Ph-4-S(L-48b)Br
H i-Pr CF3 Ph-4-NO2
H i-Pr CF3 Ph-4-N(CH3)2
H i-Pr CF3 Ph-4-N(Et)2
H i-Pr CF3 Ph-4-(T-16)
H i-Pr CF3 Ph-4-CN
H i-Pr CF3 Ph-4-C(O)OCH3
H i-Pr CF3 Ph-4-C(O)NH2
H i-Pr CF3 Ph-4-C(O)NHCH3
H i-Pr CF3 Ph-4-C(O)NHEt
H i-Pr CF3 Ph-4-C(O)N(CH3)2
H i-Pr CF3 Ph-4-C(S)NH2
H i-Pr CF3 Ph-3-Ph
H i-Pr CF3 Ph-4-Ph
H i-Pr CF3 Ph-4-(L-5a)
H i-Pr CF3 Ph-4-(L-14a)
H i-Pr CF3 Ph-4-(L-24a)
H i-Pr CF3 Ph-4-(L-36a)
H i-Pr CF3 Ph-2,4-F2
H i-Pr CF3 Ph-3,4-F2
H i-Pr CF3 Ph-2-Cl-4-F
H i-Pr CF3 Ph-3-Cl-4-F
H i-Pr CF3 Ph-2-F-4-Cl
H i-Pr CF3 Ph-3-F-4-Cl
H i-Pr CF3 Ph-2,4-Cl2
H i-Pr CF3 Ph-3,4-Cl2
H i-Pr CF3 Ph-3,5-Cl2
H i-Pr CF3 Ph-3-Br-4-F
H i-Pr CF3 Ph-2-F-4-Br
H i-Pr CF3 Ph-3,4-Br2
H i-Pr CF3 Ph-3-CH3-4-F
H i-Pr CF3 Ph-3-F-4-CH3
H i-Pr CF3 Ph-3,4-(CH3)2
H i-Pr CF3 Ph-3-CF3-4-F
H i-Pr CF3 Ph-3-CF3-4-Cl
H i-Pr CF3 Ph-2-F-4-CF3
H i-Pr CF3 Ph-3-F-4-CF3
H i-Pr CF3 Ph-2-Cl-4-CF3
H i-Pr CF3 Ph-3-Br-4-OCH3
H i-Pr CF3 Ph-3-F-4-OCHF2
H i-Pr CF3 Ph-3-Cl-4-OCHF2
H i-Pr CF3 Ph-3-Br-4-OCHF2
H i-Pr CF3 Ph-3-F-4-OCF3
H i-Pr CF3 Ph-3-Cl-4-OCF3
H i-Pr CF3 Ph-3-Br-4-OCF3
H i-Pr CF3 Ph-3-F-4-OCF2Br
H i-Pr CF3 Ph-3-Cl-4-OCF2Br
H i-Pr CF3 Ph-3-Br-4-OCF2Br
H i-Pr CF3 Ph-3-F-4-OCF2CHF2
H i-Pr CF3 Ph-3-Cl-4-OCF2CHF2
H i-Pr CF3 Ph-3-Br-4-OCF2CHF2
H i-Pr CF3 Ph-3-F-4-OCF2CHFCl
H i-Pr CF3 Ph-3-Cl-4-OCF2CHFCl
H i-Pr CF3 Ph-3-Br-4-OCF2CHFCl
H i-Pr CF3 Ph-3-F-4-OCF2CHFCF3
H i-Pr CF3 Ph-3-Cl-4-OCF2CHFCF3
H i-Pr CF3 Ph-3-Br-4-OCF2CHFCF3
H i-Pr CF3 Ph-3-F-4-OCF2CHFOCF3
H i-Pr CF3 Ph-3-Cl-4-OCF2CHFOCF3
H i-Pr CF3 Ph-3-Br-4-OCF2CHFOCF3
H i-Pr CF3 Ph-3-CH3-4-OCF2CHFOCF3
H i-Pr CF3 Ph-3-F-4-OCF2CHFOCF2CF2CF3
H i-Pr CF3 Ph-3-Cl-4-OCF2CHFOCF2CF2CF3
H i-Pr CF3 Ph-3-Br-4-OCF2CHFOCF2CF2CF3
H i-Pr CF3 Ph(-3-OCF2O-4-)
H i-Pr CF3 Ph(-3-OCF2CF2O-4-)
H i-Pr CF3 Ph-3-OPh-4-F
H i-Pr CF3 Ph-3-NO2-4-F
H i-Pr CF3 Ph-3-NO2-4-Cl
H i-Pr CF3 Ph-3-CN-4-F
H i-Pr CF3 Ph-2,3,4-F3
H i-Pr CF3 Ph-2,4,5-F3
H i-Pr CF3 Ph-3,4,5-F3
H i-Pr CF3 Ph-2,3-F2-4-CH3
H i-Pr CF3 Ph-2,3-F2-4-CF3
H i-Pr CF3 Ph-3,4-F2-5-CF3
H i-Pr CF3 Ph-2-F-3-Cl-5-CF3
H i-Pr CF3 Ph-3,5-Cl2-4-OCH3
H i-Pr CF3 1-Naph
H i-Pr CF3 2-Naph
H i-Pr CF3 L-1a
H i-Pr CF3 (L-1b)Br
H i-Pr CF3 (L-1c)Cl
H i-Pr CF3 (L-1c)Br
H i-Pr CF3 (L-1c)I
H i-Pr CF3 (L-1c)CF3
H i-Pr CF3 (L-1c)SCH3
H i-Pr CF3 (L-1c)SO2CH3
H i-Pr CF3 (L-1c)NO2
H i-Pr CF3 L-2a
H i-Pr CF3 (L-2b)Br
H i-Pr CF3 L-3a
H i-Pr CF3 (L-3b)Cl
H i-Pr CF3 (L-3b)Br
H i-Pr CF3 (L-3b)SCH3
H i-Pr CF3 (L-3b)SO2CH3
H i-Pr CF3 (L-3c)F
H i-Pr CF3 (L-3c)Cl
H i-Pr CF3 (L-3c)Br
H i-Pr CF3 (L-3c)I
H i-Pr CF3 (L-3c)CF3
H i-Pr CF3 (L-3c)SCH3
H i-Pr CF3 (L-3c)SO2CH3
H i-Pr CF3 (L-3c)NO2
H i-Pr CF3 (L-3c)CN
H i-Pr CF3 L-3d
H i-Pr CF3 L-4a
H i-Pr CF3 (L-4b)Cl
H i-Pr CF3 (L-4b)Br
H i-Pr CF3 (L-4b)NO2
H i-Pr CF3 (L-4b)CN
H i-Pr CF3 (L-6a)Cl
H i-Pr CF3 (L-6a)Br
H i-Pr CF3 (L-6b)Cl
H i-Pr CF3 (L-6b)Br
H i-Pr CF3 (L-6b)NO2
H i-Pr CF3 L-8a
H i-Pr CF3 L-10a
H i-Pr CF3 (L-10b)Cl
H i-Pr CF3 (L-10b)Br
H i-Pr CF3 (L-10b)SCH3
H i-Pr CF3 L-11a
H i-Pr CF3 (L-15a)CHF2
H i-Pr CF3 (L-15b)CF3
H i-Pr CF3 (L-16a)CHF2
H i-Pr CF3 (L-16a)CF2Br
H i-Pr CF3 (L-17a)Cl
H i-Pr CF3 L-19a
H i-Pr CF3 L-20a
H i-Pr CF3 L-21a
H i-Pr CF3 (L-21b)Cl
H i-Pr CF3 (L-21b)Br
H i-Pr CF3 (L-21b)I
H i-Pr CF3 (L-21b)CF3
H i-Pr CF3 (L-21b)NO2
H i-Pr CF3 L-22a
H i-Pr CF3 (L-22b)Cl
H i-Pr CF3 (L-22b)CF3
H i-Pr CF3 (L-22b)SCH3
H i-Pr CF3 L-23a
H i-Pr CF3 (L-23b)Cl
H i-Pr CF3 (L-23b)Br
H i-Pr CF3 (L-23b)SCH3
H i-Pr CF3 (L-23b)NO2
H i-Pr CF3 (L-23c)Cl
H i-Pr CF3 (L-23c)Br
H i-Pr CF3 (L-23c)SCH3
H i-Pr CF3 (L-25a)Cl
H i-Pr CF3 (L-25a)Br
H i-Pr CF3 (L-25a)I
H i-Pr CF3 (L-25a)CF3
H i-Pr CF3 L-25b
H i-Pr CF3 (L-30a)SCH3
H i-Pr CF3 (L-31a)Cl
H i-Pr CF3 (L-31a)Br
H i-Pr CF3 (L-31a)SCH3
H i-Pr CF3 (L-34a)Ph
H i-Pr CF3 (L-35a)Ph
H i-Pr CF3 (L-38a)Cl
H i-Pr CF3 (L-38a)Br
H i-Pr CF3 (L-38a)NO2
H i-Pr CF3 L-45a
H i-Pr CF3 (L-45b)Cl
H i-Pr CF3 (L-45c)F
H i-Pr CF3 (L-45c)Cl
H i-Pr CF3 (L-45c)Br
H i-Pr CF3 (L-45c)I
H i-Pr CF3 (L-45c)CF3
H i-Pr CF3 (L-45c)NO2
H i-Pr CF3 (L-45d)F
H i-Pr CF3 (L-45d)Cl
H i-Pr CF3 (L-45d)Br
H i-Pr CF3 L-45e
H i-Pr CF3 L-45f
H i-Pr CF3 L-46a
H i-Pr CF3 (L-46b)Br
H i-Pr CF3 (L-46c)F
H i-Pr CF3 (L-46c)Cl
H i-Pr CF3 (L-46c)Br
H i-Pr CF3 (L-46c)I
H i-Pr CF3 (L-46c)CF3
H i-Pr CF3 (L-46c)CH2SCH3
H i-Pr CF3 (L-46c)CH2SO2CH3
H i-Pr CF3 (L-46c)OCH2CF3
H i-Pr CF3 (L-46c)OCH(CF3)2
H i-Pr CF3 (L-46c)OSO2CH3
H i-Pr CF3 (L-46c)SCH3
H i-Pr CF3 (L-46c)SO2CH3
H i-Pr CF3 (L-46c)SEt
H i-Pr CF3 (L-46c)SPr-i
H i-Pr CF3 (L-46c)CN
H i-Pr CF3 L-46d
H i-Pr CF3 L-47a
H i-Pr CF3 (L-47b)F
H i-Pr CF3 (L-47b)Cl
H i-Pr CF3 L-47c
H i-Pr CF3 L-47d
H i-Pr CF3 L-48a
H i-Pr CF3 (L-48b)Br
H i-Pr CF3 L-50a
H i-Pr CF3 (L-50b)Cl
H i-Pr CF3 (L-50b)Br
H i-Pr CF3 (L-50b)I
H i-Pr CF3 (L-50b)SCH3
H i-Pr CF3 (L-50b)SO2CH3
H i-Pr CF3 L-51a
H i-Pr CF3 (L-51b)Cl
H i-Pr CF3 (L-51b)SCH3
H i-Pr CF3 L-53a
H i-Pr CF3 L-55a
H i-Pr CF2Cl CF2O(Ph-4-Cl)
H i-Pr CF2Cl CH=CH(Ph-4-Cl)
H i-Pr CF2Cl CH=CH(Ph-4-OCF3)
H i-Pr CF2Cl CH=CH(Ph-3,4-Cl2)
H i-Pr CF2Cl Ph-4-F
H i-Pr CF2Cl Ph-4-Cl
H i-Pr CF2Cl Ph-4-Br
H i-Pr CF2Cl Ph-4-I
H i-Pr CF2Cl Ph-4-CF3
H i-Pr CF2Cl Ph-4-OCHF2
H i-Pr CF2Cl Ph-4-OCF3
H i-Pr CF2Cl Ph-4-OCF2Br
H i-Pr CF2Cl Ph-4-OCF2CHF2
H i-Pr CF2Cl Ph-4-OCF2CHFCl
H i-Pr CF2Cl Ph-4-OCF2CHFCF3
H i-Pr CF2Cl Ph-4-OCF2CHFOCF3
H i-Pr CF2Cl Ph-4-OCF2CHFOCF2CF2CF3
H i-Pr CF2Cl Ph-4-O(L-45g)
H i-Pr CF2Cl Ph-3,4-Cl2
H i-Pr CF2Cl Ph(-3-OCF2O-4-)
H i-Pr CF2Cl Ph(-3-OCF2CF2O-4-)
H i-Pr CF2Cl (L-45c)Cl
H i-Pr CF2Cl (L-45c)Br
H i-Pr CF2Cl (L-45c)CF3
H i-Pr CF2Cl L-45e
H i-Pr CF2Cl L-45f
H i-Pr CF2Cl (L-46c)Cl
H i-Pr CF2Cl (L-46c)Br
H i-Pr CF2Cl (L-46c)CF3
H i-Pr CF2Cl L-46d
H i-Pr CFCl2 Ph-4-CF3
H i-Pr CF2Br CF2O(Ph-4-Cl)
H i-Pr CF2Br CH=CH(Ph-4-Cl)
H i-Pr CF2Br CH=CH(Ph-4-OCF3)
H i-Pr CF2Br CH=CH(Ph-3,4-Cl2)
H i-Pr CF2Br Ph-4-F
H i-Pr CF2Br Ph-4-Cl
H i-Pr CF2Br Ph-4-Br
H i-Pr CF2Br Ph-4-I
H i-Pr CF2Br Ph-4-CF3
H i-Pr CF2Br Ph-4-OCHF2
H i-Pr CF2Br Ph-4-OCF3
H i-Pr CF2Br Ph-4-OCF2Br
H i-Pr CF2Br Ph-4-OCF2CHF2
H i-Pr CF2Br Ph-4-OCF2CHFCl
H i-Pr CF2Br Ph-4-OCF2CHFCF3
H i-Pr CF2Br Ph-4-OCF2CHFOCF3
H i-Pr CF2Br Ph-4-OCF2CHFOCF2CF2CF3
H i-Pr CF2Br Ph-4-O(L-45g)
H i-Pr CF2Br Ph-3,4-Cl2
H i-Pr CF2Br Ph(-3-OCF2O-4-)
H i-Pr CF2Br Ph(-3-OCF2CF2O-4-)
H i-Pr CF2Br (L-45c)Cl
H i-Pr CF2Br (L-45c)Br
H i-Pr CF2Br (L-45c)CF3
H i-Pr CF2Br L-45e
H i-Pr CF2Br L-45f
H i-Pr CF2Br (L-46c)Cl
H i-Pr CF2Br (L-46c)Br
H i-Pr CF2Br (L-46c)CF3
H i-Pr CF2Br L-46d
H i-Pr CFClBr Ph-4-OCF3
H i-Pr CFBr2 (L-45c)CF3
H i-Pr CF2CHF2 Ph-4-Br
H i-Pr CF2CF3 CF2O(Ph-4-Cl)
H i-Pr CF2CF3 CH=CH(Ph-4-Cl)
H i-Pr CF2CF3 CH=CH(Ph-4-OCF3)
H i-Pr CF2CF3 CH=CH(Ph-3,4-Cl2)
H i-Pr CF2CF3 Ph-4-F
H i-Pr CF2CF3 Ph-4-Cl
H i-Pr CF2CF3 Ph-4-Br
H i-Pr CF2CF3 Ph-4-I
H i-Pr CF2CF3 Ph-4-CF3
H i-Pr CF2CF3 Ph-4-OCHF2
H i-Pr CF2CF3 Ph-4-OCF3
H i-Pr CF2CF3 Ph-4-OCF2Br
H i-Pr CF2CF3 Ph-4-OCF2CHF2
H i-Pr CF2CF3 Ph-4-OCF2CHFCl
H i-Pr CF2CF3 Ph-4-OCF2CHFCF3
H i-Pr CF2CF3 Ph-4-OCF2CHFOCF3
H i-Pr CF2CF3 Ph-4-OCF2CHFOCF2CF2CF3
H i-Pr CF2CF3 Ph-4-O(L-45g)
H i-Pr CF2CF3 Ph-3,4-Cl2
H i-Pr CF2CF3 Ph(-3-OCF2O-4-)
H i-Pr CF2CF3 Ph(-3-OCF2CF2O-4-)
H i-Pr CF2CF3 (L-45c)Cl
H i-Pr CF2CF3 (L-45c)Br
H i-Pr CF2CF3 (L-45c)CF3
H i-Pr CF2CF3 L-45e
H i-Pr CF2CF3 L-45f
H i-Pr CF2CF3 (L-46c)Cl
H i-Pr CF2CF3 (L-46c)Br
H i-Pr CF2CF3 (L-46c)CF3
H i-Pr CF2CF3 L-46d
H i-Pr CF2CF2Cl Ph-4-CF3
H i-Pr CFClCF3 Ph-4-OCF3
H i-Pr CFClCF2Cl (L-45c)CF3
H i-Pr CF2CF2Br Ph-4-Br
H i-Pr CFBrCF3 Ph-4-CF3
H i-Pr CF2CHFCF3 Ph-4-OCF3
H i-Pr CF2CF2CF3 CF2O(Ph-4-Cl)
H i-Pr CF2CF2CF3 CH=CH(Ph-4-Cl)
H i-Pr CF2CF2CF3 CH=CH(Ph-4-OCF3)
H i-Pr CF2CF2CF3 CH=CH(Ph-3,4-Cl2)
H i-Pr CF2CF2CF3 Ph-4-F
H i-Pr CF2CF2CF3 Ph-4-Cl
H i-Pr CF2CF2CF3 Ph-4-Br
H i-Pr CF2CF2CF3 Ph-4-I
H i-Pr CF2CF2CF3 Ph-4-CF3
H i-Pr CF2CF2CF3 Ph-4-OCHF2
H i-Pr CF2CF2CF3 Ph-4-OCF3
H i-Pr CF2CF2CF3 Ph-4-OCF2Br
H i-Pr CF2CF2CF3 Ph-4-OCF2CHF2
H i-Pr CF2CF2CF3 Ph-4-OCF2CHFCl
H i-Pr CF2CF2CF3 Ph-4-OCF2CHFCF3
H i-Pr CF2CF2CF3 Ph-4-OCF2CHFOCF3
H i-Pr CF2CF2CF3 Ph-4-OCF2CHFOCF2CF2CF3
H i-Pr CF2CF2CF3 Ph-4-O(L-45g)
H i-Pr CF2CF2CF3 Ph-3,4-Cl2
H i-Pr CF2CF2CF3 Ph(-3-OCF2O-4-)
H i-Pr CF2CF2CF3 Ph(-3-OCF2CF2O-4-)
H i-Pr CF2CF2CF3 (L-45c)Cl
H i-Pr CF2CF2CF3 (L-45c)Br
H i-Pr CF2CF2CF3 (L-45c)CF3
H i-Pr CF2CF2CF3 L-45e
H i-Pr CF2CF2CF3 L-45f
H i-Pr CF2CF2CF3 (L-46c)Cl
H i-Pr CF2CF2CF3 (L-46c)Br
H i-Pr CF2CF2CF3 (L-46c)CF3
H i-Pr CF2CF2CF3 L-46d
H i-Pr CF(CF3)2 (L-45c)CF3
H i-Pr CF2CFClCF2Cl Ph-4-Br
H i-Pr CF2CFBrCF2Cl Ph-4-CF3
H i-Pr CF2CF2CF2CHF2 Ph-4-OCF3
H i-Pr CF2CF2CF2CF3 (L-45c)CF3
H i-Pr CF(CF3)CF2CF3 Ph-4-Br
H i-Pr CF2CF2CF2CF2Cl Ph-4-CF3
H i-Pr CF2CF2CF2CF2CF2CF3 Ph-4-OCF3
H i-Pr T-1 (L-45c)CF3
H i-Pr T-2 Ph-4-Br
H i-Pr CH2OCH3 Ph-4-CF3
H i-Pr CH2OEt Ph-4-OCF3
H i-Pr CH2OCH2CF3 (L-45c)CF3
H i-Pr CH2OCH(CF3)2 Ph-4-Br
H i-Pr CF2OCH3 CF2O(Ph-4-Cl)
H i-Pr CF2OCH3 CH=CH(Ph-4-Cl)
H i-Pr CF2OCH3 CH=CH(Ph-4-OCF3)
H i-Pr CF2OCH3 CH=CH(Ph-3,4-Cl2)
H i-Pr CF2OCH3 Ph-4-F
H i-Pr CF2OCH3 Ph-4-Cl
H i-Pr CF2OCH3 Ph-4-Br
H i-Pr CF2OCH3 Ph-4-I
H i-Pr CF2OCH3 Ph-4-CF3
H i-Pr CF2OCH3 Ph-4-OCHF2
H i-Pr CF2OCH3 Ph-4-OCF3
H i-Pr CF2OCH3 Ph-4-OCF2Br
H i-Pr CF2OCH3 Ph-4-OCF2CHF2
H i-Pr CF2OCH3 Ph-4-OCF2CHFCl
H i-Pr CF2OCH3 Ph-4-OCF2CHFCF3
H i-Pr CF2OCH3 Ph-4-OCF2CHFOCF3
H i-Pr CF2OCH3 Ph-4-OCF2CHFOCF2CF2CF3
H i-Pr CF2OCH3 Ph-4-O(L-45g)
H i-Pr CF2OCH3 Ph-3,4-Cl2
H i-Pr CF2OCH3 Ph(-3-OCF2O-4-)
H i-Pr CF2OCH3 Ph(-3-OCF2CF2O-4-)
H i-Pr CF2OCH3 (L-45c)Cl
H i-Pr CF2OCH3 (L-45c)Br
H i-Pr CF2OCH3 (L-45c)CF3
H i-Pr CF2OCH3 L-45e
H i-Pr CF2OCH3 L-45f
H i-Pr CF2OCH3 (L-46c)Cl
H i-Pr CF2OCH3 (L-46c)Br
H i-Pr CF2OCH3 (L-46c)CF3
H i-Pr CF2OCH3 L-46d
H i-Pr CF2OCF2CF2CF3 Ph-4-CF3
H i-Pr CF2OCF2CF2OCF3 Ph-4-OCF3
H i-Pr CF(CF3)OCH3 (L-45c)CF3
H i-Pr CF(CF3)OCF2CF2CF3 Ph-4-Br
H i-Pr CH2SCH3 Ph-4-CF3
H i-Pr CH2SO2CH3 Ph-4-OCF3
H i-Pr CH2SEt (L-45c)CF3
H i-Pr CH2SCF3 Ph-4-Br
H i-Pr CH2SPh Ph-4-CF3
H i-Pr CH2CH2SCH3 Ph-4-OCF3
H i-Pr CH2CH2SCF3 (L-45c)CF3
H i-Pr CF2SCH3 CF2O(Ph-4-Cl)
H i-Pr CF2SCH3 CH=CH(Ph-4-Cl)
H i-Pr CF2SCH3 CH=CH(Ph-4-OCF3)
H i-Pr CF2SCH3 CH=CH(Ph-3,4-Cl2)
H i-Pr CF2SCH3 Ph-4-F
H i-Pr CF2SCH3 Ph-4-Cl
H i-Pr CF2SCH3 Ph-4-Br
H i-Pr CF2SCH3 Ph-4-I
H i-Pr CF2SCH3 Ph-4-CF3
H i-Pr CF2SCH3 Ph-4-OCHF2
H i-Pr CF2SCH3 Ph-4-OCF3
H i-Pr CF2SCH3 Ph-4-OCF2Br
H i-Pr CF2SCH3 Ph-4-OCF2CHF2
H i-Pr CF2SCH3 Ph-4-OCF2CHFCl
H i-Pr CF2SCH3 Ph-4-OCF2CHFCF3
H i-Pr CF2SCH3 Ph-4-OCF2CHFOCF3
H i-Pr CF2SCH3 Ph-4-OCF2CHFOCF2CF2CF3
H i-Pr CF2SCH3 Ph-4-O(L-45g)
H i-Pr CF2SCH3 Ph-3,4-Cl2
H i-Pr CF2SCH3 Ph(-3-OCF2O-4-)
H i-Pr CF2SCH3 Ph(-3-OCF2CF2O-4-)
H i-Pr CF2SCH3 (L-45c)Cl
H i-Pr CF2SCH3 (L-45c)Br
H i-Pr CF2SCH3 (L-45c)CF3
H i-Pr CF2SCH3 L-45e
H i-Pr CF2SCH3 L-45f
H i-Pr CF2SCH3 (L-46c)Cl
H i-Pr CF2SCH3 (L-46c)Br
H i-Pr CF2SCH3 (L-46c)CF3
H i-Pr CF2SCH3 L-46d
H i-Pr CF2SEt Ph-4-Br
H i-Pr CF2SPr-n Ph-4-CF3
H i-Pr CF2SPr-i Ph-4-OCF3
H i-Pr CF2SCH2Ph (L-45c)CF3
H i-Pr CF2SPh Ph-4-Br
H i-Pr CF2C(O)OEt Ph-4-CF3
H i-Pr CF2SO2N(CH3)2 Ph-4-OCF3
H i-Pr CN (L-45c)CF3
H i-Pr C(O)OCH3 Ph-4-Br
H i-Pr C(O)OEt Ph-4-CF3
H i-Pr C(O)OPr-n Ph-4-OCF3
H i-Pr C(O)OPr-i (L-45c)CF3
H i-Pr C(O)OBu-n Ph-4-Br
H i-Pr C(O)OBu-t Ph-4-CF3
H i-Pr C(O)SEt Ph-4-OCF3
H i-Pr C(O)NH2 (L-45c)CF3
H i-Pr C(S)NH2 Ph-4-Br
H i-Pr C(CH3)=NOCH3 Ph-4-CF3
H i-Pr Ph Ph-4-OCF3
H i-Pr Ph-4-F (L-45c)CF3
H i-Pr Ph-4-Cl Ph-4-Br
H i-Pr Ph-4-CF3 Ph-4-CF3
H i-Pr Ph-4-OCF3 Ph-4-OCF3
CH3 i-Pr CF3 Ph-4-Br
CH3 i-Pr CF3 Ph-4-CF3
CH3 i-Pr CF3 Ph-4-OCF3
CH3 i-Pr CF3 (L-45c)CF3
Et i-Pr CF3 (L-45c)CF3
i-Pr i-Pr CF3 Ph-4-Br
CH2OCH3 i-Pr CF3 Ph-4-CF3
CH2OEt i-Pr CF3 Ph-4-OCF3
H c-Pr CF3 CF2O(Ph-4-Cl)
H c-Pr CF3 CH=CH(Ph-4-Cl)
H c-Pr CF3 CH=CH(Ph-4-OCF3)
H c-Pr CF3 CH=CH(Ph-3,4-Cl2)
H c-Pr CF3 Ph-4-F
H c-Pr CF3 Ph-4-Cl
H c-Pr CF3 Ph-4-Br
H c-Pr CF3 Ph-4-I
H c-Pr CF3 Ph-4-CF3
H c-Pr CF3 Ph-4-OCHF2
H c-Pr CF3 Ph-4-OCF3
H c-Pr CF3 Ph-4-OCF2Br
H c-Pr CF3 Ph-4-OCF2CHF2
H c-Pr CF3 Ph-4-OCF2CHFCl
H c-Pr CF3 Ph-4-OCF2CHFCF3
H c-Pr CF3 Ph-4-OCF2CHFOCF3
H c-Pr CF3 Ph-4-OCF2CHFOCF2CF2CF3
H c-Pr CF3 Ph-4-O(L-45g)
H c-Pr CF3 Ph-3,4-Cl2
H c-Pr CF3 Ph(-3-OCF2O-4-)
H c-Pr CF3 Ph(-3-OCF2CF2O-4-)
H c-Pr CF3 (L-45c)Cl
H c-Pr CF3 (L-45c)Br
H c-Pr CF3 (L-45c)CF3
H c-Pr CF3 L-45e
H c-Pr CF3 L-45f
H c-Pr CF3 (L-46c)Cl
H c-Pr CF3 (L-46c)Br
H c-Pr CF3 (L-46c)CF3
H c-Pr CF3 L-46d
H n-Bu CF3 CH=CH(Ph-4-Cl)
H n-Bu CF3 Ph-4-Cl
H n-Bu CF3 Ph-4-Br
H n-Bu CF3 Ph-4-CF3
H n-Bu CF3 Ph-4-OCF3
H n-Bu CF3 Ph-4-OCF2Br
H n-Bu CF3 Ph-4-OCF2CHFCF3
H n-Bu CF3 Ph-4-OCF2CHFOCF3
H n-Bu CF3 Ph-4-OCF2CHFOCF2CF2CF3
H n-Bu CF3 Ph-4-O(L-45g)
H n-Bu CF3 Ph-3,4-Cl2
H n-Bu CF3 Ph(-3-OCF2O-4-)
H n-Bu CF3 Ph(-3-OCF2CF2O-4-)
H n-Bu CF3 (L-45c)CF3
H n-Bu CF3 L-45f
H n-Bu CF3 (L-46c)CF3
H n-Bu CF3 L-46d
H i-Bu CF3 (L-45c)CF3
CH3 i-Bu CF3 Ph-4-Br
H CH2Pr-c CF3 Ph-4-CF3
H s-Bu CH3 Ph-4-Br
H s-Bu CH3 Ph-4-CF3
H s-Bu CH3 Ph-4-OCF3
H s-Bu CH3 (L-45c)Cl
H s-Bu CH3 (L-45c)Br
H s-Bu CH3 (L-45c)CF3
H s-Bu Et Ph-4-OCF3
H s-Bu n-Pr (L-45c)CF3
H s-Bu i-Pr Ph-4-Br
H s-Bu c-Pr Ph-4-CF3
H s-Bu CHF2 Ph-4-OCF3
H s-Bu CF3 CF2O(Ph-4-Cl)
H s-Bu CF3 CH=CH(Ph-4-Cl)
H s-Bu CF3 CH=CH(Ph-4-OCF3)
H s-Bu CF3 CH=CH(Ph-3,4-Cl2)
H s-Bu CF3 Ph-4-F
H s-Bu CF3 Ph-4-Cl
H s-Bu CF3 Ph-4-Br
H s-Bu CF3 Ph-4-I
H s-Bu CF3 Ph-4-CF3
H s-Bu CF3 Ph-4-OCHF2
H s-Bu CF3 Ph-4-OCF3
H s-Bu CF3 Ph-4-OCF2Br
H s-Bu CF3 Ph-4-OCF2CHF2
H s-Bu CF3 Ph-4-OCF2CHFCl
H s-Bu CF3 Ph-4-OCF2CHFCF3
H s-Bu CF3 Ph-4-OCF2CHFOCF3
H s-Bu CF3 Ph-4-OCF2CHFOCF2CF2CF3
H s-Bu CF3 Ph-4-O(L-45g)
H s-Bu CF3 Ph-3,4-Cl2
H s-Bu CF3 Ph(-3-OCF2O-4-)
H s-Bu CF3 Ph(-3-OCF2CF2O-4-)
H s-Bu CF3 (L-45c)Cl
H s-Bu CF3 (L-45c)Br
H s-Bu CF3 (L-45c)CF3
H s-Bu CF3 L-45e
H s-Bu CF3 L-45f
H s-Bu CF3 (L-46c)Cl
H s-Bu CF3 (L-46c)Br
H s-Bu CF3 (L-46c)CF3
H s-Bu CF3 L-46d
H s-Bu CF2Cl (L-45c)CF3
H s-Bu CF2Br Ph-4-Br
H s-Bu CF2CF3 Ph-4-CF3
H s-Bu CF2CF2CF3 Ph-4-OCF3
H s-Bu CF2OCH3 (L-45c)CF3
H s-Bu CF2SCH3 Ph-4-Br
H t-Bu CH3 Ph-4-Br
H t-Bu CH3 Ph-4-CF3
H t-Bu CH3 Ph-4-OCF3
H t-Bu CH3 (L-45c)Cl
H t-Bu CH3 (L-45c)Br
H t-Bu CH3 (L-45c)CF3
H t-Bu Et Ph-4-CF3
H t-Bu n-Pr Ph-4-OCF3
H t-Bu i-Pr (L-45c)CF3
H t-Bu c-Pr Ph-4-Br
H t-Bu CHF2 Ph-4-CF3
H t-Bu CF3 CF2O(Ph-4-Cl)
H t-Bu CF3 CH=CH(Ph-4-Cl)
H t-Bu CF3 CH=CH(Ph-4-OCF3)
H t-Bu CF3 CH=CH(Ph-3,4-Cl2)
H t-Bu CF3 Ph-4-F
H t-Bu CF3 Ph-4-Cl
H t-Bu CF3 Ph-4-Br
H t-Bu CF3 Ph-4-I
H t-Bu CF3 Ph-4-CF3
H t-Bu CF3 Ph-4-OCHF2
H t-Bu CF3 Ph-4-OCF3
H t-Bu CF3 Ph-4-OCF2Br
H t-Bu CF3 Ph-4-OCF2CHF2
H t-Bu CF3 Ph-4-OCF2CHFCl
H t-Bu CF3 Ph-4-OCF2CHFCF3
H t-Bu CF3 Ph-4-OCF2CHFOCF3
H t-Bu CF3 Ph-4-OCF2CHFOCF2CF2CF3
H t-Bu CF3 Ph-4-O(L-45g)
H t-Bu CF3 Ph-3,4-Cl2
H t-Bu CF3 Ph(-3-OCF2O-4-)
H t-Bu CF3 Ph(-3-OCF2CF2O-4-)
H t-Bu CF3 (L-45c)Cl
H t-Bu CF3 (L-45c)Br
H t-Bu CF3 (L-45c)CF3
H t-Bu CF3 L-45e
H t-Bu CF3 L-45f
H t-Bu CF3 (L-46c)Cl
H t-Bu CF3 (L-46c)Br
H t-Bu CF3 (L-46c)CF3
H t-Bu CF3 L-46d
H t-Bu CF2Cl Ph-4-OCF3
H t-Bu CF2Br (L-45c)CF3
H t-Bu CF2CF3 Ph-4-Br
H t-Bu CF2CF2CF3 Ph-4-CF3
H t-Bu CF2OCH3 Ph-4-OCF3
H t-Bu CF2SCH3 (L-45c)CF3
H c-Bu CF3 Ph-4-Br
H n-Pen CF3 Ph-4-CF3
H CH2CH2Pr-i CF3 Ph-4-OCF3
H CH2CH(CH3)Et CF3 (L-45c)CF3
H CH2Bu-t CF3 Ph-4-Br
H CH(CH3)Pr-n CF3 CF2O(Ph-4-Cl)
H CH(CH3)Pr-n CF3 CH=CH(Ph-4-Cl)
H CH(CH3)Pr-n CF3 CH=CH(Ph-4-OCF3)
H CH(CH3)Pr-n CF3 CH=CH(Ph-3,4-Cl2)
H CH(CH3)Pr-n CF3 Ph-4-F
H CH(CH3)Pr-n CF3 Ph-4-Cl
H CH(CH3)Pr-n CF3 Ph-4-Br
H CH(CH3)Pr-n CF3 Ph-4-I
H CH(CH3)Pr-n CF3 Ph-4-CF3
H CH(CH3)Pr-n CF3 Ph-4-OCHF2
H CH(CH3)Pr-n CF3 Ph-4-OCF3
H CH(CH3)Pr-n CF3 Ph-4-OCF2Br
H CH(CH3)Pr-n CF3 Ph-4-OCF2CHF2
H CH(CH3)Pr-n CF3 Ph-4-OCF2CHFCl
H CH(CH3)Pr-n CF3 Ph-4-OCF2CHFCF3
H CH(CH3)Pr-n CF3 Ph-4-OCF2CHFOCF3
H CH(CH3)Pr-n CF3 Ph-4-OCF2CHFOCF2CF2CF3
H CH(CH3)Pr-n CF3 Ph-4-O(L-45g)
H CH(CH3)Pr-n CF3 Ph-3,4-Cl2
H CH(CH3)Pr-n CF3 Ph(-3-OCF2O-4-)
H CH(CH3)Pr-n CF3 Ph(-3-OCF2CF2O-4-)
H CH(CH3)Pr-n CF3 (L-45c)Cl
H CH(CH3)Pr-n CF3 (L-45c)Br
H CH(CH3)Pr-n CF3 (L-45c)CF3
H CH(CH3)Pr-n CF3 L-45e
H CH(CH3)Pr-n CF3 L-45f
H CH(CH3)Pr-n CF3 (L-46c)Cl
H CH(CH3)Pr-n CF3 (L-46c)Br
H CH(CH3)Pr-n CF3 (L-46c)CF3
H CH(CH3)Pr-n CF3 L-46d
H CH(CH3)Pr-i CF3 Ph-4-CF3
H CH(Et)2 CF3 Ph-4-OCF3
H C(CH3)2Et CF3 Ph-4-Br
H C(CH3)2Et CF3 Ph-4-CF3
H C(CH3)2Et CF3 Ph-4-OCF3
H C(CH3)2Et CF3 (L-45c)CF3
H c-Pen CF3 (L-45c)CF3
H n-Hex CF3 Ph-4-Br
H CH(CH3)Bu-i CF3 Ph-4-CF3
H C(CH3)2Pr-n CF3 Ph-4-Br
H C(CH3)2Pr-n CF3 Ph-4-CF3
H C(CH3)2Pr-n CF3 Ph-4-OCF3
H C(CH3)2Pr-n CF3 (L-45c)CF3
H c-Hex CF3 Ph-4-OCF3
H CH2Hex-c CF3 (L-45c)CF3
H Oct CF3 Ph-4-Br
H C(CH3)2CH2Bu-t CF3 Ph-4-CF3
-CH2CH2CH2CH2- CF3 Ph-4-OCF3
-CH2CH2CH2CH2CH2- CF3 (L-45c)CF3
-CH2CH2CH(CH3)CH2CH2- CF3 Ph-4-Br
-CH2CH(CH3)CH2CH(CH3)CH2- CF3 Ph-4-CF3
-CH2CH2CH2CH2CH2CH2- CF3 Ph-4-OCF3
H CH2CH2F CF3 (L-45c)CF3
H CH2CH2Cl CF3 Ph-4-Br
H CH2CF3 CF3 Ph-4-CF3
H CH(CH3)CH2F CF3 Ph-4-Br
H CH(CH3)CH2F CF3 Ph-4-CF3
H CH(CH3)CH2F(S) CF3 Ph-4-CF3
H CH(CH3)CH2F CF3 Ph-4-OCF3
H CH(CH3)CH2F CF3 (L-45c)CF3
H CH(CH3)CH2Cl CF3 Ph-4-Br
H CH(CH3)CH2Cl CF3 Ph-4-CF3
H CH(CH3)CH2Cl CF3 Ph-4-OCF3
H CH(CH3)CH2Cl CF3 (L-45c)CF3
H CH(CH3)CH2Br CF3 Ph-4-OCF3
H CH(CH3)CH2Br(R) CF3 Ph-4-OCF3
H CH(CH3)CH2Br(S) CF3 Ph-4-OCF3
H C(CH3)2CH2Cl CF3 Ph-4-Br
H C(CH3)2CH2Cl CF3 Ph-4-CF3
H C(CH3)2CH2Cl CF3 Ph-4-OCF3
H C(CH3)2CH2Cl CF3 (L-45c)CF3
H C(CH3)2CH2Br CF3 (L-45c)CF3
H C(CH3)2CHBrCH2Br CF3 Ph-4-Br
H CH2OCH3 CF3 Ph-4-CF3
H CH2CH2OCH3 CF3 Ph-4-OCF3
H CH2CH2OEt CF3 (L-45c)CF3
CH2CH2OEt CH2CH2OEt CF3 Ph-4-Br
H CH2CH2OC(O)NHEt CF3 Ph-4-CF3
H CH2CH2OPh CF3 Ph-4-OCF3
H CH2CH2O(Ph-2-Cl) CF3 (L-45c)CF3
H CH2CH2O(Ph-3-Cl) CF3 Ph-4-Br
H CH2CH2O(Ph-4-Cl) CF3 Ph-4-CF3
H CH2CH(OH)CH3 CF3 Ph-4-OCF3
H CH2CH(OH)Et CF3 (L-45c)CF3
H CH2CH(OH)Ph CF3 Ph-4-Br
H CH2CH(OH)CH2Ph CF3 Ph-4-CF3
H CH2C(CH3)2OSi(CH3)3 CF3 CH=CH(Ph-4-Cl)
H CH2C(CH3)2OSi(CH3)3 CF3 Ph-4-Cl
H CH2C(CH3)2OSi(CH3)3 CF3 Ph-4-Br
H CH2C(CH3)2OSi(CH3)3 CF3 Ph-4-CF3
H CH2C(CH3)2OSi(CH3)3 CF3 Ph-4-OCF3
H CH2C(CH3)2OSi(CH3)3 CF3 Ph-4-OCF2Br
H CH2C(CH3)2OSi(CH3)3 CF3 Ph-4-OCF2CHFCF3
H CH2C(CH3)2OSi(CH3)3 CF3 Ph-4-OCF2CHFOCF3
H CH2C(CH3)2OSi(CH3)3 CF3 Ph-4-OCF2CHFOCF2CF2CF3
H CH2C(CH3)2OSi(CH3)3 CF3 Ph-4-O(L-45g)
H CH2C(CH3)2OSi(CH3)3 CF3 Ph-3,4-Cl2
H CH2C(CH3)2OSi(CH3)3 CF3 Ph(-3-OCF2O-4-)
H CH2C(CH3)2OSi(CH3)3 CF3 Ph(-3-OCF2CF2O-4-)
H CH2C(CH3)2OSi(CH3)3 CF3 (L-45c)CF3
H CH2C(CH3)2OSi(CH3)3 CF3 L-45f
H CH2C(CH3)2OSi(CH3)3 CF3 (L-46c)CF3
H CH2C(CH3)2OSi(CH3)3 CF3 L-46d
H CH2CH(OEt)2 CF3 Ph-4-OCF3
H CH(CH3)CH2OH CF3 (L-45c)CF3
H CH(CH3)CH2OH(R) CF3 (L-45c)CF3
H CH(CH3)CH2OH(S) CF3 (L-45c)CF3
H CH(CH3)CH2OCH3 CH3 Ph-4-Br
H CH(CH3)CH2OCH3 CH3 Ph-4-CF3
H CH(CH3)CH2OCH3 CH3 Ph-4-OCF3
H CH(CH3)CH2OCH3 CH3 (L-45c)Cl
H CH(CH3)CH2OCH3 CH3 (L-45c)Br
H CH(CH3)CH2OCH3 CH3 (L-45c)CF3
H CH(CH3)CH2OCH3 Et Ph-4-Br
H CH(CH3)CH2OCH3 n-Pr Ph-4-CF3
H CH(CH3)CH2OCH3 i-Pr Ph-4-OCF3
H CH(CH3)CH2OCH3 c-Pr (L-45c)CF3
H CH(CH3)CH2OCH3 CHF2 Ph-4-Br
H CH(CH3)CH2OCH3 CF3 CF2O(Ph-4-Cl)
H CH(CH3)CH2OCH3 CF3 CH=CH(Ph-4-Cl)
H CH(CH3)CH2OCH3 CF3 CH=CH(Ph-4-OCF3)
H CH(CH3)CH2OCH3 CF3 CH=CH(Ph-3,4-Cl2)
H CH(CH3)CH2OCH3 CF3 Ph-4-F
H CH(CH3)CH2OCH3 CF3 Ph-4-Cl
H CH(CH3)CH2OCH3 CF3 Ph-4-Br
H CH(CH3)CH2OCH3 CF3 Ph-4-I
H CH(CH3)CH2OCH3 CF3 Ph-4-CF3
H CH(CH3)CH2OCH3 CF3 Ph-4-OCHF2
H CH(CH3)CH2OCH3 CF3 Ph-4-OCF3
H CH(CH3)CH2OCH3 CF3 Ph-4-OCF2Br
H CH(CH3)CH2OCH3 CF3 Ph-4-OCF2CHF2
H CH(CH3)CH2OCH3 CF3 Ph-4-OCF2CHFCl
H CH(CH3)CH2OCH3 CF3 Ph-4-OCF2CHFCF3
H CH(CH3)CH2OCH3 CF3 Ph-4-OCF2CHFOCF3
H CH(CH3)CH2OCH3 CF3 Ph-4-OCF2CHFOCF2CF2CF3
H CH(CH3)CH2OCH3 CF3 Ph-4-O(L-45g)
H CH(CH3)CH2OCH3 CF3 Ph-3,4-Cl2
H CH(CH3)CH2OCH3 CF3 Ph(-3-OCF2O-4-)
H CH(CH3)CH2OCH3 CF3 Ph(-3-OCF2CF2O-4-)
H CH(CH3)CH2OCH3 CF3 (L-45c)Cl
H CH(CH3)CH2OCH3 CF3 (L-45c)Br
H CH(CH3)CH2OCH3 CF3 (L-45c)CF3
H CH(CH3)CH2OCH3 CF3 L-45e
H CH(CH3)CH2OCH3 CF3 L-45f
H CH(CH3)CH2OCH3 CF3 (L-46c)Cl
H CH(CH3)CH2OCH3 CF3 (L-46c)Br
H CH(CH3)CH2OCH3 CF3 (L-46c)CF3
H CH(CH3)CH2OCH3 CF3 L-46d
H CH(CH3)CH2OCH3 CF2Cl Ph-4-CF3
H CH(CH3)CH2OCH3 CF2Br Ph-4-OCF3
H CH(CH3)CH2OCH3 CF2CF3 (L-45c)CF3
H CH(CH3)CH2OCH3 CF2CF2CF3 Ph-4-Br
H CH(CH3)CH2OCH3 CF2OCH3 Ph-4-CF3
H CH(CH3)CH2OCH3 CF2SCH3 Ph-4-OCF3
H CH(CH3)CH2OEt CF3 (L-45c)CF3
H CH(CH3)CH2OPr-n CF3 Ph-4-Br
H CH(CH3)CH2OBu-i CF3 Ph-4-CF3
H CH(CH3)CH2OCH2CH2OCH3 CF3 Ph-4-OCF3
H CH(CH3)CH2OCH2CH2SCH3 CF3 (L-45c)CF3
H CH(CH3)CH2OCH2CH2SEt CF3 Ph-4-Br
H CH(CH3)CH2OCH2Ph CF3 Ph-4-CF3
H CH(CH3)CH2OC(O)CH3 CF3 CH=CH(Ph-4-Cl)
H CH(CH3)CH2OC(O)CH3 CF3 Ph-4-Cl
H CH(CH3)CH2OC(O)CH3 CF3 Ph-4-Br
H CH(CH3)CH2OC(O)CH3 CF3 Ph-4-CF3
H CH(CH3)CH2OC(O)CH3 CF3 Ph-4-OCF3
H CH(CH3)CH2OC(O)CH3 CF3 Ph-4-OCF2Br
H CH(CH3)CH2OC(O)CH3 CF3 Ph-4-OCF2CHFCF3
H CH(CH3)CH2OC(O)CH3 CF3 Ph-4-OCF2CHFOCF3
H CH(CH3)CH2OC(O)CH3 CF3 Ph-4-OCF2CHFOCF2CF2CF3
H CH(CH3)CH2OC(O)CH3 CF3 Ph-4-O(L-45g)
H CH(CH3)CH2OC(O)CH3 CF3 Ph-3,4-Cl2
H CH(CH3)CH2OC(O)CH3 CF3 Ph(-3-OCF2O-4-)
H CH(CH3)CH2OC(O)CH3 CF3 Ph(-3-OCF2CF2O-4-)
H CH(CH3)CH2OC(O)CH3 CF3 (L-45c)CF3
H CH(CH3)CH2OC(O)CH3 CF3 L-45f
H CH(CH3)CH2OC(O)CH3 CF3 (L-46c)CF3
H CH(CH3)CH2OC(O)CH3 CF3 L-46d
H CH(CH3)CH2OC(O)CF3 CF3 Ph-4-OCF3
H CH(CH3)CH2OC(O)NHCH3 CF3 CF2O(Ph-4-Cl)
H CH(CH3)CH2OC(O)NHCH3 CF3 CH=CH(Ph-4-Cl)
H CH(CH3)CH2OC(O)NHCH3 CF3 CH=CH(Ph-4-Br)
H CH(CH3)CH2OC(O)NHCH3 CF3 CH=CH(Ph-4-CF3)
H CH(CH3)CH2OC(O)NHCH3 CF3 CH=CH(Ph-4-OCF3)
H CH(CH3)CH2OC(O)NHCH3 CF3 CH=CH(Ph-3,4-Cl2)
H CH(CH3)CH2OC(O)NHCH3 CF3 Ph-4-F
H CH(CH3)CH2OC(O)NHCH3 CF3 Ph-4-Cl
H CH(CH3)CH2OC(O)NHCH3 CF3 Ph-4-Br
H CH(CH3)CH2OC(O)NHCH3 CF3 Ph-4-CF3
H CH(CH3)CH2OC(O)NHCH3 CF3 Ph-4-OCF3
H CH(CH3)CH2OC(O)NHCH3 CF3 Ph-4-OCF2Br
H CH(CH3)CH2OC(O)NHCH3 CF3 Ph-4-OCF2CHF2
H CH(CH3)CH2OC(O)NHCH3 CF3 Ph-4-OCF2CHFCF3
H CH(CH3)CH2OC(O)NHCH3 CF3 Ph-4-OCF2CHFOCF3
H CH(CH3)CH2OC(O)NHCH3 CF3 Ph-4-OCF2CHFOCF2CF2CF3
H CH(CH3)CH2OC(O)NHCH3 CF3 Ph-4-O(L-45g)
H CH(CH3)CH2OC(O)NHCH3 CF3 Ph-3,4-F2
H CH(CH3)CH2OC(O)NHCH3 CF3 Ph-3-F-4-Cl
H CH(CH3)CH2OC(O)NHCH3 CF3 Ph-3,4-Cl2
H CH(CH3)CH2OC(O)NHCH3 CF3 Ph(-3-OCF2O-4-)
H CH(CH3)CH2OC(O)NHCH3 CF3 Ph(-3-OCF2CF2O-4-)
H CH(CH3)CH2OC(O)NHCH3 CF3 (L-45c)CF3
H CH(CH3)CH2OC(O)NHCH3 CF3 L-45f
H CH(CH3)CH2OC(O)NHCH3 CF3 (L-46c)CF3
H CH(CH3)CH2OC(O)NHCH3 CF3 L-46d
H CH(CH3)CH2OC(O)NHEt CH3 Ph-4-Br
H CH(CH3)CH2OC(O)NHEt CH3 Ph-4-CF3
H CH(CH3)CH2OC(O)NHEt CH3 Ph-4-OCF3
H CH(CH3)CH2OC(O)NHEt CH3 (L-45c)Cl
H CH(CH3)CH2OC(O)NHEt CH3 (L-45c)Br
H CH(CH3)CH2OC(O)NHEt CH3 (L-45c)CF3
H CH(CH3)CH2OC(O)NHEt Et (L-45c)CF3
H CH(CH3)CH2OC(O)NHEt n-Pr Ph-4-Br
H CH(CH3)CH2OC(O)NHEt i-Pr Ph-4-CF3
H CH(CH3)CH2OC(O)NHEt c-Pr Ph-4-OCF3
H CH(CH3)CH2OC(O)NHEt CHF2 (L-45c)CF3
H CH(CH3)CH2OC(O)NHEt CF3 CF2O(Ph-4-Cl)
H CH(CH3)CH2OC(O)NHEt CF3 CH=CH(Ph-4-Cl)
H CH(CH3)CH2OC(O)NHEt CF3 CH=CH(Ph-4-Br)
H CH(CH3)CH2OC(O)NHEt CF3 CH=CH(Ph-4-CF3)
H CH(CH3)CH2OC(O)NHEt CF3 CH=CH(Ph-4-OCF3)
H CH(CH3)CH2OC(O)NHEt CF3 CH=CH(Ph-3,4-Cl2)
H CH(CH3)CH2OC(O)NHEt CF3 Ph-4-F
H CH(CH3)CH2OC(O)NHEt CF3 Ph-4-Cl
H CH(CH3)CH2OC(O)NHEt CF3 Ph-4-Br
H CH(CH3)CH2OC(O)NHEt CF3 Ph-4-I
H CH(CH3)CH2OC(O)NHEt CF3 Ph-4-CF3
H CH(CH3)CH2OC(O)NHEt CF3 Ph-4-OCHF2
H CH(CH3)CH2OC(O)NHEt CF3 Ph-4-OCF3
H CH(CH3)CH2OC(O)NHEt CF3 Ph-4-OCF2Br
H CH(CH3)CH2OC(O)NHEt CF3 Ph-4-OCF2CHF2
H CH(CH3)CH2OC(O)NHEt CF3 Ph-4-OCF2CHFCl
H CH(CH3)CH2OC(O)NHEt CF3 Ph-4-OCF2CHFCF3
H CH(CH3)CH2OC(O)NHEt CF3 Ph-4-OCF2CHFOCF3
H CH(CH3)CH2OC(O)NHEt CF3 Ph-4-OCF2CHFOCF2CF2CF3
H CH(CH3)CH2OC(O)NHEt CF3 Ph-4-O(L-45g)
H CH(CH3)CH2OC(O)NHEt CF3 Ph-3,4-F2
H CH(CH3)CH2OC(O)NHEt CF3 Ph-3-F-4-Cl
H CH(CH3)CH2OC(O)NHEt CF3 Ph-3,4-Cl2
H CH(CH3)CH2OC(O)NHEt CF3 Ph(-3-OCF2O-4-)
H CH(CH3)CH2OC(O)NHEt CF3 Ph(-3-OCF2CF2O-4-)
H CH(CH3)CH2OC(O)NHEt CF3 (L-45c)Cl
H CH(CH3)CH2OC(O)NHEt CF3 (L-45c)Br
H CH(CH3)CH2OC(O)NHEt CF3 (L-45c)CF3
H CH(CH3)CH2OC(O)NHEt CF3 L-45e
H CH(CH3)CH2OC(O)NHEt CF3 L-45f
H CH(CH3)CH2OC(O)NHEt CF3 (L-46c)Cl
H CH(CH3)CH2OC(O)NHEt CF3 (L-46c)Br
H CH(CH3)CH2OC(O)NHEt CF3 (L-46c)CF3
H CH(CH3)CH2OC(O)NHEt CF3 L-46d
H CH(CH3)CH2OC(O)NHEt CF2Cl Ph-4-Br
H CH(CH3)CH2OC(O)NHEt CF2Br Ph-4-CF3
H CH(CH3)CH2OC(O)NHEt CF2CF3 Ph-4-OCF3
H CH(CH3)CH2OC(O)NHEt CF2CF2CF3 (L-45c)CF3
H CH(CH3)CH2OC(O)NHEt CF2OCH3 Ph-4-Br
H CH(CH3)CH2OC(O)NHEt CF2SCH3 Ph-4-CF3
H CH(CH3)CH2OC(O)NHPr-n CF3 CH=CH(Ph-4-Cl)
H CH(CH3)CH2OC(O)NHPr-n CF3 Ph-4-Cl
H CH(CH3)CH2OC(O)NHPr-n CF3 Ph-4-Br
H CH(CH3)CH2OC(O)NHPr-n CF3 Ph-4-CF3
H CH(CH3)CH2OC(O)NHPr-n CF3 Ph-4-OCF3
H CH(CH3)CH2OC(O)NHPr-n CF3 Ph-4-OCF2Br
H CH(CH3)CH2OC(O)NHPr-n CF3 Ph-4-OCF2CHFCF3
H CH(CH3)CH2OC(O)NHPr-n CF3 Ph-4-OCF2CHFOCF3
H CH(CH3)CH2OC(O)NHPr-n CF3 Ph-4-OCF2CHFOCF2CF2CF3
H CH(CH3)CH2OC(O)NHPr-n CF3 Ph-4-O(L-45g)
H CH(CH3)CH2OC(O)NHPr-n CF3 Ph-3,4-Cl2
H CH(CH3)CH2OC(O)NHPr-n CF3 Ph(-3-OCF2O-4-)
H CH(CH3)CH2OC(O)NHPr-n CF3 Ph(-3-OCF2CF2O-4-)
H CH(CH3)CH2OC(O)NHPr-n CF3 (L-45c)CF3
H CH(CH3)CH2OC(O)NHPr-n CF3 L-45f
H CH(CH3)CH2OC(O)NHPr-n CF3 (L-46c)CF3
H CH(CH3)CH2OC(O)NHPr-n CF3 L-46d
H CH(CH3)CH2OC(O)NHPr-i CF3 CH=CH(Ph-4-Cl)
H CH(CH3)CH2OC(O)NHPr-i CF3 Ph-4-Cl
H CH(CH3)CH2OC(O)NHPr-i CF3 Ph-4-Br
H CH(CH3)CH2OC(O)NHPr-i CF3 Ph-4-CF3
H CH(CH3)CH2OC(O)NHPr-i CF3 Ph-4-OCF3
H CH(CH3)CH2OC(O)NHPr-i CF3 Ph-4-OCF2Br
H CH(CH3)CH2OC(O)NHPr-i CF3 Ph-4-OCF2CHFCF3
H CH(CH3)CH2OC(O)NHPr-i CF3 Ph-4-OCF2CHFOCF3
H CH(CH3)CH2OC(O)NHPr-i CF3 Ph-4-OCF2CHFOCF2CF2CF3
H CH(CH3)CH2OC(O)NHPr-i CF3 Ph-4-O(L-45g)
H CH(CH3)CH2OC(O)NHPr-i CF3 Ph-3,4-Cl2
H CH(CH3)CH2OC(O)NHPr-i CF3 Ph(-3-OCF2O-4-)
H CH(CH3)CH2OC(O)NHPr-i CF3 Ph(-3-OCF2CF2O-4-)
H CH(CH3)CH2OC(O)NHPr-i CF3 (L-45c)CF3
H CH(CH3)CH2OC(O)NHPr-i CF3 L-45f
H CH(CH3)CH2OC(O)NHPr-i CF3 (L-46c)CF3
H CH(CH3)CH2OC(O)NHPr-i CF3 L-46d
H CH(CH3)CH2OC(O)NHPr-c CF3 CH=CH(Ph-4-Cl)
H CH(CH3)CH2OC(O)NHPr-c CF3 Ph-4-Cl
H CH(CH3)CH2OC(O)NHPr-c CF3 Ph-4-Br
H CH(CH3)CH2OC(O)NHPr-c CF3 Ph-4-CF3
H CH(CH3)CH2OC(O)NHPr-c CF3 Ph-4-OCF3
H CH(CH3)CH2OC(O)NHPr-c CF3 Ph-4-OCF2Br
H CH(CH3)CH2OC(O)NHPr-c CF3 Ph-4-OCF2CHFCF3
H CH(CH3)CH2OC(O)NHPr-c CF3 Ph-4-OCF2CHFOCF3
H CH(CH3)CH2OC(O)NHPr-c CF3 Ph-4-OCF2CHFOCF2CF2CF3
H CH(CH3)CH2OC(O)NHPr-c CF3 Ph-4-O(L-45g)
H CH(CH3)CH2OC(O)NHPr-c CF3 Ph-3,4-Cl2
H CH(CH3)CH2OC(O)NHPr-c CF3 Ph(-3-OCF2O-4-)
H CH(CH3)CH2OC(O)NHPr-c CF3 Ph(-3-OCF2CF2O-4-)
H CH(CH3)CH2OC(O)NHPr-c CF3 (L-45c)CF3
H CH(CH3)CH2OC(O)NHPr-c CF3 L-45f
H CH(CH3)CH2OC(O)NHPr-c CF3 (L-46c)CF3
H CH(CH3)CH2OC(O)NHPr-c CF3 L-46d
H CH(CH3)CH2OC(O)NHBu-t CF3 Ph-4-OCF3
H CH(CH3)CH2OC(O)NHCH2CF3 CF3 (L-45c)CF3
H CH(CH3)CH2OC(O)NHCH2CH2OCH3 CF3 Ph-4-Br
H CH(CH3)CH2OC(O)NHCH2CH2SCH3 CF3 Ph-4-CF3
H CH(CH3)CH2OC(O)NHCH2CH2CH2SCH3 CF3 Ph-4-OCF3
H CH(CH3)CH2OC(O)NHCH2CH=CH2 CF3 (L-45c)CF3
H CH(CH3)CH2OC(O)NHCH2Ph CF3 CH=CH(Ph-4-Cl)
H CH(CH3)CH2OC(O)NHCH2Ph CF3 Ph-4-Cl
H CH(CH3)CH2OC(O)NHCH2Ph CF3 Ph-4-Br
H CH(CH3)CH2OC(O)NHCH2Ph CF3 Ph-4-CF3
H CH(CH3)CH2OC(O)NHCH2Ph CF3 Ph-4-OCF3
H CH(CH3)CH2OC(O)NHCH2Ph CF3 Ph-4-OCF2Br
H CH(CH3)CH2OC(O)NHCH2Ph CF3 Ph-4-OCF2CHFCF3
H CH(CH3)CH2OC(O)NHCH2Ph CF3 Ph-4-OCF2CHFOCF3
H CH(CH3)CH2OC(O)NHCH2Ph CF3 Ph-4-OCF2CHFOCF2CF2CF3
H CH(CH3)CH2OC(O)NHCH2Ph CF3 Ph-4-O(L-45g)
H CH(CH3)CH2OC(O)NHCH2Ph CF3 Ph-3,4-Cl2
H CH(CH3)CH2OC(O)NHCH2Ph CF3 Ph(-3-OCF2O-4-)
H CH(CH3)CH2OC(O)NHCH2Ph CF3 Ph(-3-OCF2CF2O-4-)
H CH(CH3)CH2OC(O)NHCH2Ph CF3 (L-45c)CF3
H CH(CH3)CH2OC(O)NHCH2Ph CF3 L-45f
H CH(CH3)CH2OC(O)NHCH2Ph CF3 (L-46c)CF3
H CH(CH3)CH2OC(O)NHCH2Ph CF3 L-46d
H CH(CH3)CH2OC(O)NHCH2(Ph-4-Cl) CF3 Ph-4-Br
H CH(CH3)CH2OC(O)NHCH2(Ph-4-OCH3) CF3 Ph-4-CF3
H CH(CH3)CH2OC(O)NHCH2(L-46a) CF3 Ph-4-OCF3
H CH(CH3)CH2OC(O)NHCH2(L-47a) CF3 (L-45c)CF3
H CH(CH3)CH2OC(O)NHPh CF3 CH=CH(Ph-4-Cl)
H CH(CH3)CH2OC(O)NHPh CF3 Ph-4-Cl
H CH(CH3)CH2OC(O)NHPh CF3 Ph-4-Br
H CH(CH3)CH2OC(O)NHPh CF3 Ph-4-CF3
H CH(CH3)CH2OC(O)NHPh CF3 Ph-4-OCF3
H CH(CH3)CH2OC(O)NHPh CF3 Ph-4-OCF2Br
H CH(CH3)CH2OC(O)NHPh CF3 Ph-4-OCF2CHFCF3
H CH(CH3)CH2OC(O)NHPh CF3 Ph-4-OCF2CHFOCF3
H CH(CH3)CH2OC(O)NHPh CF3 Ph-4-OCF2CHFOCF2CF2CF3
H CH(CH3)CH2OC(O)NHPh CF3 Ph-4-O(L-45g)
H CH(CH3)CH2OC(O)NHPh CF3 Ph-3,4-Cl2
H CH(CH3)CH2OC(O)NHPh CF3 Ph(-3-OCF2O-4-)
H CH(CH3)CH2OC(O)NHPh CF3 Ph(-3-OCF2CF2O-4-)
H CH(CH3)CH2OC(O)NHPh CF3 (L-45c)CF3
H CH(CH3)CH2OC(O)NHPh CF3 L-45f
H CH(CH3)CH2OC(O)NHPh CF3 (L-46c)CF3
H CH(CH3)CH2OC(O)NHPh CF3 L-46d
H CH(CH3)CH2OC(O)N(CH3)2 CF3 Ph-4-Br
H CH(CH3)CH2OC(O)N(Et)2 CF3 CH=CH(Ph-4-Cl)
H CH(CH3)CH2OC(O)N(Et)2 CF3 Ph-4-Cl
H CH(CH3)CH2OC(O)N(Et)2 CF3 Ph-4-Br
H CH(CH3)CH2OC(O)N(Et)2 CF3 Ph-4-CF3
H CH(CH3)CH2OC(O)N(Et)2 CF3 Ph-4-OCF3
H CH(CH3)CH2OC(O)N(Et)2 CF3 Ph-4-OCF2Br
H CH(CH3)CH2OC(O)N(Et)2 CF3 Ph-4-OCF2CHFCF3
H CH(CH3)CH2OC(O)N(Et)2 CF3 Ph-4-OCF2CHFOCF3
H CH(CH3)CH2OC(O)N(Et)2 CF3 Ph-4-OCF2CHFOCF2CF2CF3
H CH(CH3)CH2OC(O)N(Et)2 CF3 Ph-4-O(L-45g)
H CH(CH3)CH2OC(O)N(Et)2 CF3 Ph-3,4-Cl2
H CH(CH3)CH2OC(O)N(Et)2 CF3 Ph(-3-OCF2O-4-)
H CH(CH3)CH2OC(O)N(Et)2 CF3 Ph(-3-OCF2CF2O-4-)
H CH(CH3)CH2OC(O)N(Et)2 CF3 (L-45c)CF3
H CH(CH3)CH2OC(O)N(Et)2 CF3 L-45f
H CH(CH3)CH2OC(O)N(Et)2 CF3 (L-46c)CF3
H CH(CH3)CH2OC(O)N(Et)2 CF3 L-46d
H CH(CH3)CH2OC(O)N(Pr-i)2 CF3 Ph-4-CF3
H CH(CH3)CH2OC(O)N(CH3)Ph CF3 Ph-4-OCF3
H CH(CH3)CH2OC(O)(T-16) CF3 (L-45c)CF3
H CH(CH3)CH2OC(O)(T-19) CF3 Ph-4-Br
H CH(CH3)CH2OC(O)(T-20) CF3 Ph-4-CF3
H CH(CH3)CH2OC(O)(T-21) CF3 Ph-4-OCF3
H CH(CH3)CH2OP(O)(OEt)2 CF3 (L-45c)CF3
H CH(CH3)CH2OP(S)(OCH3)2 CF3 CH=CH(Ph-4-Cl)
H CH(CH3)CH2OP(S)(OCH3)2 CF3 Ph-4-Cl
H CH(CH3)CH2OP(S)(OCH3)2 CF3 Ph-4-Br
H CH(CH3)CH2OP(S)(OCH3)2 CF3 Ph-4-CF3
H CH(CH3)CH2OP(S)(OCH3)2 CF3 Ph-4-OCF3
H CH(CH3)CH2OP(S)(OCH3)2 CF3 Ph-4-OCF2Br
H CH(CH3)CH2OP(S)(OCH3)2 CF3 Ph-4-OCF2CHFCF3
H CH(CH3)CH2OP(S)(OCH3)2 CF3 Ph-4-OCF2CHFOCF3
H CH(CH3)CH2OP(S)(OCH3)2 CF3 Ph-4-OCF2CHFOCF2CF2CF3
H CH(CH3)CH2OP(S)(OCH3)2 CF3 Ph-4-O(L-45g)
H CH(CH3)CH2OP(S)(OCH3)2 CF3 Ph-3,4-Cl2
H CH(CH3)CH2OP(S)(OCH3)2 CF3 Ph(-3-OCF2O-4-)
H CH(CH3)CH2OP(S)(OCH3)2 CF3 Ph(-3-OCF2CF2O-4-)
H CH(CH3)CH2OP(S)(OCH3)2 CF3 (L-45c)CF3
H CH(CH3)CH2OP(S)(OCH3)2 CF3 L-45f
H CH(CH3)CH2OP(S)(OCH3)2 CF3 (L-46c)CF3
H CH(CH3)CH2OP(S)(OCH3)2 CF3 L-46d
H CH(CH3)CH2OP(S)(OEt)2 CF3 CH=CH(Ph-4-Cl)
H CH(CH3)CH2OP(S)(OEt)2 CF3 Ph-4-Cl
H CH(CH3)CH2OP(S)(OEt)2 CF3 Ph-4-Br
H CH(CH3)CH2OP(S)(OEt)2 CF3 Ph-4-CF3
H CH(CH3)CH2OP(S)(OEt)2 CF3 Ph-4-OCF3
H CH(CH3)CH2OP(S)(OEt)2 CF3 Ph-4-OCF2Br
H CH(CH3)CH2OP(S)(OEt)2 CF3 Ph-4-OCF2CHFCF3
H CH(CH3)CH2OP(S)(OEt)2 CF3 Ph-4-OCF2CHFOCF3
H CH(CH3)CH2OP(S)(OEt)2 CF3 Ph-4-OCF2CHFOCF2CF2CF3
H CH(CH3)CH2OP(S)(OEt)2 CF3 Ph-4-O(L-45g)
H CH(CH3)CH2OP(S)(OEt)2 CF3 Ph-3,4-Cl2
H CH(CH3)CH2OP(S)(OEt)2 CF3 Ph(-3-OCF2O-4-)
H CH(CH3)CH2OP(S)(OEt)2 CF3 Ph(-3-OCF2CF2O-4-)
H CH(CH3)CH2OP(S)(OEt)2 CF3 (L-45c)CF3
H CH(CH3)CH2OP(S)(OEt)2 CF3 L-45f
H CH(CH3)CH2OP(S)(OEt)2 CF3 (L-46c)CF3
H CH(CH3)CH2OP(S)(OEt)2 CF3 L-46d
H CH(CH3)CH2OPh CF3 Ph-4-Br
H CH(CH3)CH2O(Ph-4-Cl) CF3 CH=CH(Ph-4-Cl)
H CH(CH3)CH2O(Ph-4-Cl) CF3 Ph-4-Cl
H CH(CH3)CH2O(Ph-4-Cl) CF3 Ph-4-Br
H CH(CH3)CH2O(Ph-4-Cl) CF3 Ph-4-CF3
H CH(CH3)CH2O(Ph-4-Cl) CF3 Ph-4-OCF3
H CH(CH3)CH2O(Ph-4-Cl) CF3 Ph-4-OCF2Br
H CH(CH3)CH2O(Ph-4-Cl) CF3 Ph-4-OCF2CHFCF3
H CH(CH3)CH2O(Ph-4-Cl) CF3 Ph-4-OCF2CHFOCF3
H CH(CH3)CH2O(Ph-4-Cl) CF3 Ph-4-OCF2CHFOCF2CF2CF3
H CH(CH3)CH2O(Ph-4-Cl) CF3 Ph-4-O(L-45g)
H CH(CH3)CH2O(Ph-4-Cl) CF3 Ph-3,4-Cl2
H CH(CH3)CH2O(Ph-4-Cl) CF3 Ph(-3-OCF2O-4-)
H CH(CH3)CH2O(Ph-4-Cl) CF3 Ph(-3-OCF2CF2O-4-)
H CH(CH3)CH2O(Ph-4-Cl) CF3 (L-45c)CF3
H CH(CH3)CH2O(Ph-4-Cl) CF3 L-45f
H CH(CH3)CH2O(Ph-4-Cl) CF3 (L-46c)CF3
H CH(CH3)CH2O(Ph-4-Cl) CF3 L-46d
H CH(CH3)CH2O(Ph-3-CF3) CF3 Ph-4-CF3
H CH(Et)CH2OH CF3 Ph-4-OCF3
H CH(Et)CH2OCH3 CF3 (L-45c)CF3
H CH(Ph)CH2OH CF3 Ph-4-Br
H CH(Ph)CH2OH(R) CF3 Ph-4-Br
H CH(Ph-2-Cl)CH2OH CF3 Ph-4-CF3
H CH(Ph-4-Cl)CH2OH CF3 Ph-4-OCF3
H CH(Ph-4-Ph)CH2OH CF3 (L-45c)CF3
H C(CH3)2CH2OH CF3 Ph-4-Br
H CH(CH3)CH2OCH3 CH3 Ph-4-Br
H C(CH3)2CH2OCH3 CH3 Ph-4-CF3
H C(CH3)2CH2OCH3 CH3 Ph-4-OCF3
H C(CH3)2CH2OCH3 CH3 (L-45c)Cl
H C(CH3)2CH2OCH3 CH3 (L-45c)Br
H C(CH3)2CH2OCH3 CH3 (L-45c)CF3
H C(CH3)2CH2OCH3 Et Ph-4-CF3
H C(CH3)2CH2OCH3 n-Pr Ph-4-OCF3
H C(CH3)2CH2OCH3 i-Pr (L-45c)CF3
H C(CH3)2CH2OCH3 c-Pr Ph-4-Br
H C(CH3)2CH2OCH3 CHF2 Ph-4-CF3
H C(CH3)2CH2OCH3 CF3 CF2O(Ph-4-Cl)
H C(CH3)2CH2OCH3 CF3 CH=CH(Ph-4-Cl)
H C(CH3)2CH2OCH3 CF3 CH=CH(Ph-4-OCF3)
H C(CH3)2CH2OCH3 CF3 CH=CH(Ph-3,4-Cl2)
H C(CH3)2CH2OCH3 CF3 Ph-4-F
H C(CH3)2CH2OCH3 CF3 Ph-4-Cl
H C(CH3)2CH2OCH3 CF3 Ph-4-Br
H C(CH3)2CH2OCH3 CF3 Ph-4-I
H C(CH3)2CH2OCH3 CF3 Ph-4-CF3
H C(CH3)2CH2OCH3 CF3 Ph-4-OCHF2
H C(CH3)2CH2OCH3 CF3 Ph-4-OCF3
H C(CH3)2CH2OCH3 CF3 Ph-4-OCF2Br
H C(CH3)2CH2OCH3 CF3 Ph-4-OCF2CHF2
H C(CH3)2CH2OCH3 CF3 Ph-4-OCF2CHFCl
H C(CH3)2CH2OCH3 CF3 Ph-4-OCF2CHFCF3
H C(CH3)2CH2OCH3 CF3 Ph-4-OCF2CHFOCF3
H C(CH3)2CH2OCH3 CF3 Ph-4-OCF2CHFOCF2CF2CF3
H C(CH3)2CH2OCH3 CF3 Ph-4-O(L-45g)
H C(CH3)2CH2OCH3 CF3 Ph-3,4-Cl2
H C(CH3)2CH2OCH3 CF3 Ph(-3-OCF2O-4-)
H C(CH3)2CH2OCH3 CF3 Ph(-3-OCF2CF2O-4-)
H C(CH3)2CH2OCH3 CF3 (L-45c)Cl
H C(CH3)2CH2OCH3 CF3 (L-45c)Br
H C(CH3)2CH2OCH3 CF3 (L-45c)CF3
H C(CH3)2CH2OCH3 CF3 L-45e
H C(CH3)2CH2OCH3 CF3 L-45f
H C(CH3)2CH2OCH3 CF3 (L-46c)Cl
H C(CH3)2CH2OCH3 CF3 (L-46c)Br
H C(CH3)2CH2OCH3 CF3 (L-46c)CF3
H C(CH3)2CH2OCH3 CF3 L-46d
H C(CH3)2CH2OCH3 CF2Cl Ph-4-OCF3
H C(CH3)2CH2OCH3 CF2Br (L-45c)CF3
H C(CH3)2CH2OCH3 CF2CF3 Ph-4-Br
H C(CH3)2CH2OCH3 CF2CF2CF3 Ph-4-CF3
H C(CH3)2CH2OCH3 CF2OCH3 Ph-4-OCF3
H C(CH3)2CH2OCH3 CF2SCH3 (L-45c)CF3
H C(CH3)2CH2OC(O)CH3 CF3 Ph-4-Br
H C(CH3)2CH2OC(O)CF3 CF3 Ph-4-CF3
H C(CH3)2CH2OC(O)NHCH3 CH3 Ph-4-Br
H C(CH3)2CH2OC(O)NHCH3 CH3 Ph-4-CF3
H C(CH3)2CH2OC(O)NHCH3 CH3 Ph-4-OCF3
H C(CH3)2CH2OC(O)NHCH3 CH3 (L-45c)Cl
H C(CH3)2CH2OC(O)NHCH3 CH3 (L-45c)Br
H C(CH3)2CH2OC(O)NHCH3 CH3 (L-45c)CF3
H C(CH3)2CH2OC(O)NHCH3 Et Ph-4-OCF3
H C(CH3)2CH2OC(O)NHCH3 n-Pr (L-45c)CF3
H C(CH3)2CH2OC(O)NHCH3 i-Pr Ph-4-Br
H C(CH3)2CH2OC(O)NHCH3 c-Pr Ph-4-CF3
H C(CH3)2CH2OC(O)NHCH3 CHF2 Ph-4-OCF3
H C(CH3)2CH2OC(O)NHCH3 CF3 CF2O(Ph-4-Cl)
H C(CH3)2CH2OC(O)NHCH3 CF3 CH=CH(Ph-4-Cl)
H C(CH3)2CH2OC(O)NHCH3 CF3 CH=CH(Ph-4-Br)
H C(CH3)2CH2OC(O)NHCH3 CF3 CH=CH(Ph-4-CF3)
H C(CH3)2CH2OC(O)NHCH3 CF3 CH=CH(Ph-4-OCF3)
H C(CH3)2CH2OC(O)NHCH3 CF3 CH=CH(Ph-3,4-Cl2)
H C(CH3)2CH2OC(O)NHCH3 CF3 Ph-4-F
H C(CH3)2CH2OC(O)NHCH3 CF3 Ph-4-Cl
H C(CH3)2CH2OC(O)NHCH3 CF3 Ph-4-Br
H C(CH3)2CH2OC(O)NHCH3 CF3 Ph-4-I
H C(CH3)2CH2OC(O)NHCH3 CF3 Ph-4-CF3
H C(CH3)2CH2OC(O)NHCH3 CF3 Ph-4-OCHF2
H C(CH3)2CH2OC(O)NHCH3 CF3 Ph-4-OCF3
H C(CH3)2CH2OC(O)NHCH3 CF3 Ph-4-OCF2Br
H C(CH3)2CH2OC(O)NHCH3 CF3 Ph-4-OCF2CHF2
H C(CH3)2CH2OC(O)NHCH3 CF3 Ph-4-OCF2CHFCl
H C(CH3)2CH2OC(O)NHCH3 CF3 Ph-4-OCF2CHFCF3
H C(CH3)2CH2OC(O)NHCH3 CF3 Ph-4-OCF2CHFOCF3
H C(CH3)2CH2OC(O)NHCH3 CF3 Ph-4-OCF2CHFOCF2CF2CF3
H C(CH3)2CH2OC(O)NHCH3 CF3 Ph-4-O(L-45g)
H C(CH3)2CH2OC(O)NHCH3 CF3 Ph-3,4-F2
H C(CH3)2CH2OC(O)NHCH3 CF3 Ph-3-F-4-Cl
H C(CH3)2CH2OC(O)NHCH3 CF3 Ph-3,4-Cl2
H C(CH3)2CH2OC(O)NHCH3 CF3 Ph(-3-OCF2O-4-)
H C(CH3)2CH2OC(O)NHCH3 CF3 Ph(-3-OCF2CF2O-4-)
H C(CH3)2CH2OC(O)NHCH3 CF3 (L-45c)Cl
H C(CH3)2CH2OC(O)NHCH3 CF3 (L-45c)Br
H C(CH3)2CH2OC(O)NHCH3 CF3 (L-45c)CF3
H C(CH3)2CH2OC(O)NHCH3 CF3 L-45e
H C(CH3)2CH2OC(O)NHCH3 CF3 L-45f
H C(CH3)2CH2OC(O)NHCH3 CF3 (L-46c)Cl
H C(CH3)2CH2OC(O)NHCH3 CF3 (L-46c)Br
H C(CH3)2CH2OC(O)NHCH3 CF3 (L-46c)CF3
H C(CH3)2CH2OC(O)NHCH3 CF3 L-46d
H C(CH3)2CH2OC(O)NHCH3 CF2Cl (L-45c)CF3
H C(CH3)2CH2OC(O)NHCH3 CF2Br Ph-4-Br
H C(CH3)2CH2OC(O)NHCH3 CF2CF3 Ph-4-CF3
H C(CH3)2CH2OC(O)NHCH3 CF2CF2CF3 Ph-4-OCF3
H C(CH3)2CH2OC(O)NHCH3 CF2OCH3 (L-45c)CF3
H C(CH3)2CH2OC(O)NHCH3 CF2SCH3 Ph-4-Br
H C(CH3)2CH2OC(O)NHEt CF3 CF2O(Ph-4-Cl)
H C(CH3)2CH2OC(O)NHEt CF3 CH=CH(Ph-4-Cl)
H C(CH3)2CH2OC(O)NHEt CF3 CH=CH(Ph-4-Br)
H C(CH3)2CH2OC(O)NHEt CF3 CH=CH(Ph-4-CF3)
H C(CH3)2CH2OC(O)NHEt CF3 CH=CH(Ph-4-OCF3)
H C(CH3)2CH2OC(O)NHEt CF3 CH=CH(Ph-3,4-Cl2)
H C(CH3)2CH2OC(O)NHEt CF3 Ph-4-F
H C(CH3)2CH2OC(O)NHEt CF3 Ph-4-Cl
H C(CH3)2CH2OC(O)NHEt CF3 Ph-4-Br
H C(CH3)2CH2OC(O)NHEt CF3 Ph-4-CF3
H C(CH3)2CH2OC(O)NHEt CF3 Ph-4-OCF3
H C(CH3)2CH2OC(O)NHEt CF3 Ph-4-OCF2Br
H C(CH3)2CH2OC(O)NHEt CF3 Ph-4-OCF2CHF2
H C(CH3)2CH2OC(O)NHEt CF3 Ph-4-OCF2CHFCF3
H C(CH3)2CH2OC(O)NHEt CF3 Ph-4-OCF2CHFOCF3
H C(CH3)2CH2OC(O)NHEt CF3 Ph-4-OCF2CHFOCF2CF2CF3
H C(CH3)2CH2OC(O)NHEt CF3 Ph-4-O(L-45g)
H C(CH3)2CH2OC(O)NHEt CF3 Ph-3,4-F2
H C(CH3)2CH2OC(O)NHEt CF3 Ph-3-F-4-Cl
H C(CH3)2CH2OC(O)NHEt CF3 Ph-3,4-Cl2
H C(CH3)2CH2OC(O)NHEt CF3 Ph(-3-OCF2O-4-)
H C(CH3)2CH2OC(O)NHEt CF3 Ph(-3-OCF2CF2O-4-)
H C(CH3)2CH2OC(O)NHEt CF3 (L-45c)CF3
H C(CH3)2CH2OC(O)NHEt CF3 L-45f
H C(CH3)2CH2OC(O)NHEt CF3 (L-46c)CF3
H C(CH3)2CH2OC(O)NHEt CF3 L-46d
H C(CH3)2CH2OC(O)NHPr-n CF3 CH=CH(Ph-4-Cl)
H C(CH3)2CH2OC(O)NHPr-n CF3 Ph-4-Cl
H C(CH3)2CH2OC(O)NHPr-n CF3 Ph-4-Br
H C(CH3)2CH2OC(O)NHPr-n CF3 Ph-4-CF3
H C(CH3)2CH2OC(O)NHPr-n CF3 Ph-4-OCF3
H C(CH3)2CH2OC(O)NHPr-n CF3 Ph-4-OCF2Br
H C(CH3)2CH2OC(O)NHPr-n CF3 Ph-4-OCF2CHFCF3
H C(CH3)2CH2OC(O)NHPr-n CF3 Ph-4-OCF2CHFOCF3
H C(CH3)2CH2OC(O)NHPr-n CF3 Ph-4-OCF2CHFOCF2CF2CF3
H C(CH3)2CH2OC(O)NHPr-n CF3 Ph-4-O(L-45g)
H C(CH3)2CH2OC(O)NHPr-n CF3 Ph-3,4-Cl2
H C(CH3)2CH2OC(O)NHPr-n CF3 Ph(-3-OCF2O-4-)
H C(CH3)2CH2OC(O)NHPr-n CF3 Ph(-3-OCF2CF2O-4-)
H C(CH3)2CH2OC(O)NHPr-n CF3 (L-45c)CF3
H C(CH3)2CH2OC(O)NHPr-n CF3 L-45f
H C(CH3)2CH2OC(O)NHPr-n CF3 (L-46c)CF3
H C(CH3)2CH2OC(O)NHPr-n CF3 L-46d
H C(CH3)2CH2OC(O)NHPr-i CF3 Ph-4-CF3
H C(CH3)2CH2OC(O)NHPr-c CF3 Ph-4-OCF3
H C(CH3)2CH2OC(O)NHCH2CF3 CF3 (L-45c)CF3
H C(CH3)2CH2OC(O)NHCH2CH2OCH3 CF3 Ph-4-Br
H C(CH3)2CH2OC(O)NHCH2CH2SCH3 CF3 Ph-4-CF3
H C(CH3)2CH2OC(O)NHCH2CH2CH2SCH3 CF3 Ph-4-OCF3
H C(CH3)2CH2OC(O)NHCH2CH=CH2 CF3 Ph-4-CF3
H C(CH3)2CH2OC(O)NHCH2Ph CF3 CH=CH(Ph-4-Cl)
H C(CH3)2CH2OC(O)NHCH2Ph CF3 Ph-4-Cl
H C(CH3)2CH2OC(O)NHCH2Ph CF3 Ph-4-Br
H C(CH3)2CH2OC(O)NHCH2Ph CF3 Ph-4-CF3
H C(CH3)2CH2OC(O)NHCH2Ph CF3 Ph-4-OCF3
H C(CH3)2CH2OC(O)NHCH2Ph CF3 Ph-4-OCF2Br
H C(CH3)2CH2OC(O)NHCH2Ph CF3 Ph-4-OCF2CHFCF3
H C(CH3)2CH2OC(O)NHCH2Ph CF3 Ph-4-OCF2CHFOCF3
H C(CH3)2CH2OC(O)NHCH2Ph CF3 Ph-4-OCF2CHFOCF2CF2CF3
H C(CH3)2CH2OC(O)NHCH2Ph CF3 Ph-4-O(L-45g)
H C(CH3)2CH2OC(O)NHCH2Ph CF3 Ph-3,4-Cl2
H C(CH3)2CH2OC(O)NHCH2Ph CF3 Ph(-3-OCF2O-4-)
H C(CH3)2CH2OC(O)NHCH2Ph CF3 Ph(-3-OCF2CF2O-4-)
H C(CH3)2CH2OC(O)NHCH2Ph CF3 (L-45c)CF3
H C(CH3)2CH2OC(O)NHCH2Ph CF3 L-45f
H C(CH3)2CH2OC(O)NHCH2Ph CF3 (L-46c)CF3
H C(CH3)2CH2OC(O)NHCH2Ph CF3 L-46d
H C(CH3)2CH2OC(O)N(CH3)2 CF3 CH=CH(Ph-4-Cl)
H C(CH3)2CH2OC(O)N(CH3)2 CF3 Ph-4-Cl
H C(CH3)2CH2OC(O)N(CH3)2 CF3 Ph-4-Br
H C(CH3)2CH2OC(O)N(CH3)2 CF3 Ph-4-CF3
H C(CH3)2CH2OC(O)N(CH3)2 CF3 Ph-4-OCF3
H C(CH3)2CH2OC(O)N(CH3)2 CF3 Ph-4-OCF2Br
H C(CH3)2CH2OC(O)N(CH3)2 CF3 Ph-4-OCF2CHFCF3
H C(CH3)2CH2OC(O)N(CH3)2 CF3 Ph-4-OCF2CHFOCF3
H C(CH3)2CH2OC(O)N(CH3)2 CF3 Ph-4-OCF2CHFOCF2CF2CF3
H C(CH3)2CH2OC(O)N(CH3)2 CF3 Ph-4-O(L-45g)
H C(CH3)2CH2OC(O)N(CH3)2 CF3 Ph-3,4-Cl2
H C(CH3)2CH2OC(O)N(CH3)2 CF3 Ph(-3-OCF2O-4-)
H C(CH3)2CH2OC(O)N(CH3)2 CF3 Ph(-3-OCF2CF2O-4-)
H C(CH3)2CH2OC(O)N(CH3)2 CF3 (L-45c)CF3
H C(CH3)2CH2OC(O)N(CH3)2 CF3 L-45f
H C(CH3)2CH2OC(O)N(CH3)2 CF3 (L-46c)CF3
H C(CH3)2CH2OC(O)N(CH3)2 CF3 L-46d
H C(CH3)2CH2OP(S)(OCH3)2 CF3 Ph-4-OCF3
H CH2CH2CH2OH CF3 (L-45c)CF3
H CH2CH2CH2OCH3 CF3 Ph-4-Br
H CH(CH3)CH2CH2OCH3 CF3 Ph-4-CF3
H CH(CH3)CH2CH2OEt CF3 CH=CH(Ph-4-Cl)
H CH(CH3)CH2CH2OEt CF3 Ph-4-Cl
H CH(CH3)CH2CH2OEt CF3 Ph-4-Br
H CH(CH3)CH2CH2OEt CF3 Ph-4-CF3
H CH(CH3)CH2CH2OEt CF3 Ph-4-OCF3
H CH(CH3)CH2CH2OEt CF3 Ph-4-OCF2Br
H CH(CH3)CH2CH2OEt CF3 Ph-4-OCF2CHFCF3
H CH(CH3)CH2CH2OEt CF3 Ph-4-OCF2CHFOCF3
H CH(CH3)CH2CH2OEt CF3 Ph-4-OCF2CHFOCF2CF2CF3
H CH(CH3)CH2CH2OEt CF3 Ph-4-O(L-45g)
H CH(CH3)CH2CH2OEt CF3 Ph-3,4-Cl2
H CH(CH3)CH2CH2OEt CF3 Ph(-3-OCF2O-4-)
H CH(CH3)CH2CH2OEt CF3 Ph(-3-OCF2CF2O-4-)
H CH(CH3)CH2CH2OEt CF3 (L-45c)CF3
H CH(CH3)CH2CH2OEt CF3 L-45f
H CH(CH3)CH2CH2OEt CF3 (L-46c)CF3
H CH(CH3)CH2CH2OEt CF3 L-46d
H CH(CH3)CH2CH2OPr-n CF3 Ph-4-OCF3
H CH(CH3)CH2CH2OBu-i CF3 (L-45c)CF3
H CH(CH3)CH2CH2OCH2CF3 CF3 Ph-4-Br
H CH(CH3)CH2CH2OCH2CH2OCH3 CF3 Ph-4-CF3
H CH(CH3)CH2CH2OC(O)NHEt CF3 Ph-4-OCF3
H CH2CH2CH2CH2OC(O)NHEt CF3 (L-45c)CF3
H CH2CH2CH2CH2OC(O)NHPr-i CF3 Ph-4-Br
H CH2CH2CH2CH2CH2OC(O)NHEt CF3 Ph-4-CF3
H T-10 CF3 Ph-4-OCF3
H M-4a CF3 (L-45c)CF3
H M-5a CF3 Ph-4-Br
H CH2(M-7a) CF3 Ph-4-CF3
H CH2(M-16a) CF3 Ph-4-OCF3
-CH2CH2OCH2CH2- CF3 (L-45c)CF3
H CH2SCH3 CF3 Ph-4-Br
H CH2CH2SCH3 CF3 Ph-4-CF3
H CH2CH2SEt CF3 Ph-4-OCF3
H CH2CH2SPr-i CF3 (L-45c)CF3
H CH2CH(CH3)SCH3 CF3 Ph-4-Br
H CH2CH(CH3)SO2CH3 CF3 Ph-4-CF3
H CH2CH(CH3)SEt CF3 Ph-4-OCF3
H CH2CH(CH3)SO2Et CF3 (L-45c)CF3
H CH(CH3)CH2SH CF3 Ph-4-Br
H CH(CH3)CH2SCH3 CH3 CF2O(Ph-4-Cl)
H CH(CH3)CH2SCH3 CH3 CH=CH(Ph-4-Cl)
H CH(CH3)CH2SCH3 CH3 CH=CH(Ph-4-OCF3)
H CH(CH3)CH2SCH3 CH3 CH=CH(Ph-3,4-Cl2)
H CH(CH3)CH2SCH3 CH3 Ph-4-F
H CH(CH3)CH2SCH3 CH3 Ph-4-Cl
H CH(CH3)CH2SCH3 CH3 Ph-4-Br
H CH(CH3)CH2SCH3 CH3 Ph-4-I
H CH(CH3)CH2SCH3 CH3 Ph-4-CF3
H CH(CH3)CH2SCH3 CH3 Ph-4-OCHF2
H CH(CH3)CH2SCH3 CH3 Ph-4-OCF3
H CH(CH3)CH2SCH3 CH3 Ph-4-OCF2Br
H CH(CH3)CH2SCH3 CH3 Ph-4-OCF2CHF2
H CH(CH3)CH2SCH3 CH3 Ph-4-OCF2CHFCl
H CH(CH3)CH2SCH3 CH3 Ph-4-OCF2CHFCF3
H CH(CH3)CH2SCH3 CH3 Ph-4-OCF2CHFOCF3
H CH(CH3)CH2SCH3 CH3 Ph-4-OCF2CHFOCF2CF2CF3
H CH(CH3)CH2SCH3 CH3 Ph-4-O(L-45g)
H CH(CH3)CH2SCH3 CH3 Ph-3,4-Cl2
H CH(CH3)CH2SCH3 CH3 Ph(-3-OCF2O-4-)
H CH(CH3)CH2SCH3 CH3 Ph(-3-OCF2CF2O-4-)
H CH(CH3)CH2SCH3 CH3 (L-45c)Cl
H CH(CH3)CH2SCH3 CH3 (L-45c)Br
H CH(CH3)CH2SCH3 CH3 (L-45c)CF3
H CH(CH3)CH2SCH3 CH3 L-45e
H CH(CH3)CH2SCH3 CH3 L-45f
H CH(CH3)CH2SCH3 CH3 (L-46c)Cl
H CH(CH3)CH2SCH3 CH3 (L-46c)Br
H CH(CH3)CH2SCH3 CH3 (L-46c)CF3
H CH(CH3)CH2SCH3 CH3 L-46d
H CH(CH3)CH2SCH3 Et Ph-4-Cl
H CH(CH3)CH2SCH3 Et Ph-4-Br
H CH(CH3)CH2SCH3 Et Ph-4-CF3
H CH(CH3)CH2SCH3 Et Ph-4-OCF3
H CH(CH3)CH2SCH3 Et Ph-4-OCF2Br
H CH(CH3)CH2SCH3 Et Ph-4-OCF2CHFCF3
H CH(CH3)CH2SCH3 Et Ph-4-OCF2CHFOCF3
H CH(CH3)CH2SCH3 Et Ph-4-OCF2CHFOCF2CF2CF3
H CH(CH3)CH2SCH3 Et Ph-4-O(L-45g)
H CH(CH3)CH2SCH3 Et Ph-3,4-Cl2
H CH(CH3)CH2SCH3 Et Ph(-3-OCF2O-4-)
H CH(CH3)CH2SCH3 Et Ph(-3-OCF2CF2O-4-)
H CH(CH3)CH2SCH3 Et (L-45c)CF3
H CH(CH3)CH2SCH3 n-Pr Ph-4-Br
H CH(CH3)CH2SCH3 n-Pr Ph-4-CF3
H CH(CH3)CH2SCH3 n-Pr Ph-4-OCF3
H CH(CH3)CH2SCH3 n-Pr (L-45c)CF3
H CH(CH3)CH2SCH3 i-Pr Ph-4-Br
H CH(CH3)CH2SCH3 i-Pr Ph-4-CF3
H CH(CH3)CH2SCH3 i-Pr Ph-4-OCF3
H CH(CH3)CH2SCH3 i-Pr (L-45c)CF3
H CH(CH3)CH2SCH3 c-Pr Ph-4-Br
H CH(CH3)CH2SCH3 c-Pr Ph-4-CF3
H CH(CH3)CH2SCH3 c-Pr Ph-4-OCF3
H CH(CH3)CH2SCH3 c-Pr (L-45c)CF3
H CH(CH3)CH2SCH3 n-Bu Ph-4-CF3
H CH(CH3)CH2SCH3 CH2F Ph-4-OCF3
H CH(CH3)CH2SCH3 CH2Cl (L-45c)CF3
H CH(CH3)CH2SCH3 CH2Br Ph-4-Br
H CH(CH3)CH2SCH3 CHF2 Ph-4-Cl
H CH(CH3)CH2SCH3 CHF2 Ph-4-Br
H CH(CH3)CH2SCH3 CHF2 Ph-4-CF3
H CH(CH3)CH2SCH3 CHF2 Ph-4-OCF3
H CH(CH3)CH2SCH3 CHF2 Ph-4-OCF2Br
H CH(CH3)CH2SCH3 CHF2 Ph-4-OCF2CHFCF3
H CH(CH3)CH2SCH3 CHF2 Ph-4-OCF2CHFOCF3
H CH(CH3)CH2SCH3 CHF2 Ph-4-OCF2CHFOCF2CF2CF3
H CH(CH3)CH2SCH3 CHF2 Ph-4-O(L-45g)
H CH(CH3)CH2SCH3 CHF2 Ph-3,4-Cl2
H CH(CH3)CH2SCH3 CHF2 Ph(-3-OCF2O-4-)
H CH(CH3)CH2SCH3 CHF2 Ph(-3-OCF2CF2O-4-)
H CH(CH3)CH2SCH3 CHF2 (L-45c)CF3
H CH(CH3)CH2SCH3 CHF2 L-45f
H CH(CH3)CH2SCH3 CHF2 (L-46c)CF3
H CH(CH3)CH2SCH3 CHF2 L-46d
H CH(CH3)CH2SCH3 CHFCl Ph-4-CF3
H CH(CH3)CH2SCH3 CHFBr Ph-4-OCF3
H CH(CH3)CH2SCH3 CF3 c-Pr
H CH(CH3)CH2SCH3 CF3 c-Bu
H CH(CH3)CH2SCH3 CF3 c-Pen
H CH(CH3)CH2SCH3 CF3 c-Hex
H CH(CH3)CH2SCH3 CF3 T-1
H CH(CH3)CH2SCH3 CF3 T-2
H CH(CH3)CH2SCH3 CF3 T-3
H CH(CH3)CH2SCH3 CF3 T-4
H CH(CH3)CH2SCH3 CF3 T-5
H CH(CH3)CH2SCH3 CF3 CH2OCH3
H CH(CH3)CH2SCH3 CF3 CH2OEt
H CH(CH3)CH2SCH3 CF3 CH2OPr-n
H CH(CH3)CH2SCH3 CF3 CH2OPr-i
H CH(CH3)CH2SCH3 CF3 CH2OBu-n
H CH(CH3)CH2SCH3 CF3 CH2OC(O)(Ph-2-Cl)
H CH(CH3)CH2SCH3 CF3 CH2OC(O)(Ph-3-Cl)
H CH(CH3)CH2SCH3 CF3 CH2OC(O)(Ph-4-Cl)
H CH(CH3)CH2SCH3 CF3 CH2OPh
H CH(CH3)CH2SCH3 CF3 CH2O(Ph-2-F)
H CH(CH3)CH2SCH3 CF3 CH2O(Ph-3-F)
H CH(CH3)CH2SCH3 CF3 CH2O(Ph-4-F)
H CH(CH3)CH2SCH3 CF3 CH2O(Ph-2-Cl)
H CH(CH3)CH2SCH3 CF3 CH2O(Ph-3-Cl)
H CH(CH3)CH2SCH3 CF3 CH2O(Ph-4-Cl)
H CH(CH3)CH2SCH3 CF3 CH2O(Ph-2-Br)
H CH(CH3)CH2SCH3 CF3 CH2O(Ph-3-Br)
H CH(CH3)CH2SCH3 CF3 CH2O(Ph-4-Br)
H CH(CH3)CH2SCH3 CF3 CH2O(Ph-2-CF3)
H CH(CH3)CH2SCH3 CF3 CH2O(Ph-3-CF3)
H CH(CH3)CH2SCH3 CF3 CH2O(Ph-4-CF3)
H CH(CH3)CH2SCH3 CF3 CH2O(Ph-2-OCF3)
H CH(CH3)CH2SCH3 CF3 CH2O(Ph-3-OCF3)
H CH(CH3)CH2SCH3 CF3 CH2O(Ph-4-OCF3)
H CH(CH3)CH2SCH3 CF3 CF2OPh
H CH(CH3)CH2SCH3 CF3 CF2O(Ph-2-F)
H CH(CH3)CH2SCH3 CF3 CF2O(Ph-3-F)
H CH(CH3)CH2SCH3 CF3 CF2O(Ph-4-F)
H CH(CH3)CH2SCH3 CF3 CF2O(Ph-2-Cl)
H CH(CH3)CH2SCH3 CF3 CF2O(Ph-3-Cl)
H CH(CH3)CH2SCH3 CF3 CF2O(Ph-4-Cl)
H CH(CH3)CH2SCH3 CF3 CF2O(Ph-2-Br)
H CH(CH3)CH2SCH3 CF3 CF2O(Ph-3-Br)
H CH(CH3)CH2SCH3 CF3 CF2O(Ph-4-Br)
H CH(CH3)CH2SCH3 CF3 CF2O(Ph-2-CF3)
H CH(CH3)CH2SCH3 CF3 CF2O(Ph-3-CF3)
H CH(CH3)CH2SCH3 CF3 CF2O(Ph-4-CF3)
H CH(CH3)CH2SCH3 CF3 CF2O(Ph-2-OCF3)
H CH(CH3)CH2SCH3 CF3 CF2O(Ph-3-OCF3)
H CH(CH3)CH2SCH3 CF3 CF2O(Ph-4-OCF3)
H CH(CH3)CH2SCH3 CF3 CH2S(Ph-2-Cl)
H CH(CH3)CH2SCH3 CF3 CH2S(Ph-3-Cl)
H CH(CH3)CH2SCH3 CF3 CH2S(Ph-4-Cl)
H CH(CH3)CH2SCH3 CF3 CH2SO2(Ph-2-Cl)
H CH(CH3)CH2SCH3 CF3 CH2SO2(Ph-3-Cl)
H CH(CH3)CH2SCH3 CF3 CH2SO2(Ph-4-Cl)
H CH(CH3)CH2SCH3 CF3 CH2N(CH3)2
H CH(CH3)CH2SCH3 CF3 CH2NH(Ph-2-Cl)
H CH(CH3)CH2SCH3 CF3 CH2NH(Ph-3-Cl)
H CH(CH3)CH2SCH3 CF3 CH2NH(Ph-4-Cl)
H CH(CH3)CH2SCH3 CF3 CF2C(O)OEt
H CH(CH3)CH2SCH3 CF3 CH2(L-5a)
H CH(CH3)CH2SCH3 CF3 CH2(L-14a)
H CH(CH3)CH2SCH3 CF3 CH2(L-24a)
H CH(CH3)CH2SCH3 CF3 CH2(L-36a)
H CH(CH3)CH2SCH3 CF3 CH2CH2Ph
H CH(CH3)CH2SCH3 CF3 CH2CH2(Ph-2-Cl)
H CH(CH3)CH2SCH3 CF3 CH2CH2(Ph-3-Cl)
H CH(CH3)CH2SCH3 CF3 CH2CH2(Ph-4-Cl)
H CH(CH3)CH2SCH3 CF3 T-22
H CH(CH3)CH2SCH3 CF3 T-23
H CH(CH3)CH2SCH3 CF3 T-24
H CH(CH3)CH2SCH3 CF3 C(O)OEt
H CH(CH3)CH2SCH3 CF3 C(O)OBu-t
H CH(CH3)CH2SCH3 CF3 C(O)OCH2CF3
H CH(CH3)CH2SCH3 CF3 CH=CH(Ph-2-F)
H CH(CH3)CH2SCH3 CF3 CH=CH(Ph-3-F)
H CH(CH3)CH2SCH3 CF3 CH=CH(Ph-4-F)
H CH(CH3)CH2SCH3 CF3 CH=CH(Ph-2-Cl)
H CH(CH3)CH2SCH3 CF3 CH=CH(Ph-3-Cl)
H CH(CH3)CH2SCH3 CF3 CH=CH(Ph-4-Cl)
H CH(CH3)CH2SCH3 CF3 CH=CH(Ph-2-Br)
H CH(CH3)CH2SCH3 CF3 CH=CH(Ph-3-Br)
H CH(CH3)CH2SCH3 CF3 CH=CH(Ph-4-Br)
H CH(CH3)CH2SCH3 CF3 CH=CH(Ph-2-CF3)
H CH(CH3)CH2SCH3 CF3 CH=CH(Ph-3-CF3)
H CH(CH3)CH2SCH3 CF3 CH=CH(Ph-4-CF3)
H CH(CH3)CH2SCH3 CF3 CH=CH(Ph-2-OCF3)
H CH(CH3)CH2SCH3 CF3 CH=CH(Ph-3-OCF3)
H CH(CH3)CH2SCH3 CF3 CH=CH(Ph-4-OCF3)
H CH(CH3)CH2SCH3 CF3 CH=CH(Ph-2-SCH3)
H CH(CH3)CH2SCH3 CF3 CH=CH(Ph-3-SCH3)
H CH(CH3)CH2SCH3 CF3 CH=CH(Ph-4-SCH3)
H CH(CH3)CH2SCH3 CF3 CH=CH(Ph-2-SO2CH3)
H CH(CH3)CH2SCH3 CF3 CH=CH(Ph-3-SO2CH3)
H CH(CH3)CH2SCH3 CF3 CH=CH(Ph-4-SO2CH3)
H CH(CH3)CH2SCH3 CF3 CH=CH(Ph-3,4-F2)
H CH(CH3)CH2SCH3 CF3 CH=CH(Ph-3-F-4-Cl)
H CH(CH3)CH2SCH3 CF3 CH=CH(Ph-3,4-Cl2)
H CH(CH3)CH2SCH3 CF3 CH=CH(Ph-3,4-Br2)
H CH(CH3)CH2SCH3 CF3 CH=CH(Ph-3-F-4-CF3)
H CH(CH3)CH2SCH3 CF3 CH=CH(Ph-3-Cl-4-OCF3)
H CH(CH3)CH2SCH3 CF3 CH=CH[Ph(-3-OCF2O-4-)]
H CH(CH3)CH2SCH3 CF3 Ph
H CH(CH3)CH2SCH3 CF3 Ph-2-F
H CH(CH3)CH2SCH3 CF3 Ph-3-F
H CH(CH3)CH2SCH3 CF3 Ph-4-F
H CH(CH3)CH2SCH3 CF3 Ph-2-Cl
H CH(CH3)CH2SCH3 CF3 Ph-3-Cl
H CH(CH3)CH2SCH3 CF3 Ph-4-Cl
H CH(CH3)CH2SCH3 CF3 Ph-2-Br
H CH(CH3)CH2SCH3 CF3 Ph-3-Br
H CH(CH3)CH2SCH3 CF3 Ph-4-Br
H CH(CH3)CH2SCH3 CF3 Ph-4-I
H CH(CH3)CH2SCH3 CF3 Ph-4-Bu-t
H CH(CH3)CH2SCH3 CF3 Ph-2-CF3
H CH(CH3)CH2SCH3 CF3 Ph-3-CF3
H CH(CH3)CH2SCH3 CF3 Ph-4-CF3
H CH(CH3)CH2SCH3 CF3 Ph-4-OCH3
H CH(CH3)CH2SCH3 CF3 Ph-4-OCHF2
H CH(CH3)CH2SCH3 CF3 Ph-2-OCF3
H CH(CH3)CH2SCH3 CF3 Ph-3-OCF3
H CH(CH3)CH2SCH3 CF3 Ph-4-OCF3
H CH(CH3)CH2SCH3(R) CF3 Ph-4-OCF3
H CH(CH3)CH2SCH3(S) CF3 Ph-4-OCF3
H CH(CH3)CH2SCH3 CF3 Ph-4-OCF2Br
H CH(CH3)CH2SCH3 CF3 Ph-4-OCH2CF3
H CH(CH3)CH2SCH3 CF3 Ph-4-OCF2CHF2
H CH(CH3)CH2SCH3 CF3 Ph-4-OCF2CHFCl
H CH(CH3)CH2SCH3 CF3 Ph-4-OCF2CHFBr
H CH(CH3)CH2SCH3 CF3 Ph-4-OCF2CF2Br
H CH(CH3)CH2SCH3 CF3 Ph-4-OCF2CFCl2
H CH(CH3)CH2SCH3 CF3 Ph-4-OCF2CCl3
H CH(CH3)CH2SCH3 CF3 Ph-4-OCH2CF2CHF2
H CH(CH3)CH2SCH3 CF3 Ph-3-OCF2CHFCF3
H CH(CH3)CH2SCH3 CF3 Ph-4-OCF2CHFCF3
H CH(CH3)CH2SCH3 CF3 Ph-4-OCH(CF3)2
H CH(CH3)CH2SCH3 CF3 Ph-4-OCF2CFBrCF3
H CH(CH3)CH2SCH3 CF3 Ph-3-OCF2CHFOCF3
H CH(CH3)CH2SCH3 CF3 Ph-4-OCF2CHFOCF3
H CH(CH3)CH2SCH3 CF3 Ph-4-OCF2CHFOCF2CF2CF3
H CH(CH3)CH2SCH3 CF3 Ph-4-OSO2CH3
H CH(CH3)CH2SCH3 CF3 Ph-4-OSO2CF3
H CH(CH3)CH2SCH3 CF3 Ph-3-O(Ph-4-Cl)
H CH(CH3)CH2SCH3 CF3 Ph-4-O(Ph-4-Cl)
H CH(CH3)CH2SCH3 CF3 Ph-4-O(Ph-4-Br)
H CH(CH3)CH2SCH3 CF3 Ph-4-O(Ph-4-CF3)
H CH(CH3)CH2SCH3 CF3 Ph-4-O(L-45c)Br
H CH(CH3)CH2SCH3 CF3 Ph-4-O(L-45c)CF3
H CH(CH3)CH2SCH3 CF3 Ph-3-O(L-45e)
H CH(CH3)CH2SCH3 CF3 Ph-4-O(L-45e)
H CH(CH3)CH2SCH3 CF3 Ph-4-O(L-48b)Br
H CH(CH3)CH2SCH3 CF3 Ph-4-SCH3
H CH(CH3)CH2SCH3 CF3 Ph-4-SO2CH3
H CH(CH3)CH2SCH3 CF3 Ph-3-S(Ph-4-Cl)
H CH(CH3)CH2SCH3 CF3 Ph-4-S(Ph-4-Cl)
H CH(CH3)CH2SCH3 CF3 Ph-4-S(Ph-4-Br)
H CH(CH3)CH2SCH3 CF3 Ph-4-S(Ph-4-CF3)
H CH(CH3)CH2SCH3 CF3 Ph-4-S(L-45c)Br
H CH(CH3)CH2SCH3 CF3 Ph-4-S(L-45c)CF3
H CH(CH3)CH2SCH3 CF3 Ph-4-S(L-45e)
H CH(CH3)CH2SCH3 CF3 Ph-4-S(L-48b)Br
H CH(CH3)CH2SCH3 CF3 Ph-4-NO2
H CH(CH3)CH2SCH3 CF3 Ph-4-CN
H CH(CH3)CH2SCH3 CF3 Ph-2,3-F2
H CH(CH3)CH2SCH3 CF3 Ph-2,4-F2
H CH(CH3)CH2SCH3 CF3 Ph-3,4-F2
H CH(CH3)CH2SCH3 CF3 Ph-2,5-F2
H CH(CH3)CH2SCH3 CF3 Ph-3,5-F2
H CH(CH3)CH2SCH3 CF3 Ph-2-Cl-4-F
H CH(CH3)CH2SCH3 CF3 Ph-2-F-3-Cl
H CH(CH3)CH2SCH3 CF3 Ph-3-Cl-4-F
H CH(CH3)CH2SCH3 CF3 Ph-2-F-4-Cl
H CH(CH3)CH2SCH3 CF3 Ph-3-F-4-Cl
H CH(CH3)CH2SCH3 CF3 Ph-2,3-Cl2
H CH(CH3)CH2SCH3 CF3 Ph-2,4-Cl2
H CH(CH3)CH2SCH3 CF3 Ph-2,5-Cl2
H CH(CH3)CH2SCH3 CF3 Ph-3,4-Cl2
H CH(CH3)CH2SCH3 CF3 Ph-3,5-Cl2
H CH(CH3)CH2SCH3 CF3 Ph-3-Br-4-F
H CH(CH3)CH2SCH3 CF3 Ph-2-F-4-Br
H CH(CH3)CH2SCH3 CF3 Ph-2-F-5-Br
H CH(CH3)CH2SCH3 CF3 Ph-3,4-Br2
H CH(CH3)CH2SCH3 CF3 Ph-3,5-Br2
H CH(CH3)CH2SCH3 CF3 Ph-3-CH3-4-F
H CH(CH3)CH2SCH3 CF3 Ph-3-F-4-CH3
H CH(CH3)CH2SCH3 CF3 Ph-2-F-5-CH3
H CH(CH3)CH2SCH3 CF3 Ph-2,4-(CH3)2
H CH(CH3)CH2SCH3 CF3 Ph-3,4-(CH3)2
H CH(CH3)CH2SCH3 CF3 Ph-2-F-3-CF3
H CH(CH3)CH2SCH3 CF3 Ph-3-CF3-4-F
H CH(CH3)CH2SCH3 CF3 Ph-3-CF3-4-Cl
H CH(CH3)CH2SCH3 CF3 Ph-2-F-4-CF3
H CH(CH3)CH2SCH3 CF3 Ph-3-F-4-CF3
H CH(CH3)CH2SCH3 CF3 Ph-2-F-5-CF3
H CH(CH3)CH2SCH3 CF3 Ph-3-F-5-CF3
H CH(CH3)CH2SCH3 CF3 Ph-2-Cl-4-CF3
H CH(CH3)CH2SCH3 CF3 Ph-3,5-(CF3)2
H CH(CH3)CH2SCH3 CF3 Ph-3-Br-4-OCH3
H CH(CH3)CH2SCH3 CF3 Ph-3-F-4-OCHF2
H CH(CH3)CH2SCH3 CF3 Ph-3-Cl-4-OCHF2
H CH(CH3)CH2SCH3 CF3 Ph-3-Br-4-OCHF2
H CH(CH3)CH2SCH3 CF3 Ph-3-F-4-OCF3
H CH(CH3)CH2SCH3 CF3 Ph-3-Cl-4-OCF3
H CH(CH3)CH2SCH3 CF3 Ph-3-Br-4-OCF3
H CH(CH3)CH2SCH3 CF3 Ph-3-F-4-OCF2Br
H CH(CH3)CH2SCH3 CF3 Ph-3-Cl-4-OCF2Br
H CH(CH3)CH2SCH3 CF3 Ph-3-Br-4-OCF2Br
H CH(CH3)CH2SCH3 CF3 Ph-3-F-4-OCF2CHF2
H CH(CH3)CH2SCH3 CF3 Ph-3-Cl-4-OCF2CHF2
H CH(CH3)CH2SCH3 CF3 Ph-3-Br-4-OCF2CHF2
H CH(CH3)CH2SCH3 CF3 Ph-3-F-4-OCF2CHFCl
H CH(CH3)CH2SCH3 CF3 Ph-3-Cl-4-OCF2CHFCl
H CH(CH3)CH2SCH3 CF3 Ph-3-Br-4-OCF2CHFCl
H CH(CH3)CH2SCH3 CF3 Ph-3-F-4-OCF2CHFCF3
H CH(CH3)CH2SCH3 CF3 Ph-3-Cl-4-OCF2CHFCF3
H CH(CH3)CH2SCH3 CF3 Ph-3-Br-4-OCF2CHFCF3
H CH(CH3)CH2SCH3 CF3 Ph-3-F-4-OCF2CHFOCF3
H CH(CH3)CH2SCH3 CF3 Ph-3-Cl-4-OCF2CHFOCF3
H CH(CH3)CH2SCH3 CF3 Ph-3-Br-4-OCF2CHFOCF3
H CH(CH3)CH2SCH3 CF3 Ph-3-CH3-4-OCF2CHFOCF3
H CH(CH3)CH2SCH3 CF3 Ph-3-F-4-OCF2CHFOCF2CF2CF3
H CH(CH3)CH2SCH3 CF3 Ph-3-Cl-4-OCF2CHFOCF2CF2CF3
H CH(CH3)CH2SCH3 CF3 Ph-3-Br-4-OCF2CHFOCF2CF2CF3
H CH(CH3)CH2SCH3 CF3 Ph(-3-OCF2O-4-)
H CH(CH3)CH2SCH3 CF3 Ph(-3-OCF2CF2O-4-)
H CH(CH3)CH2SCH3 CF3 Ph-3-OPh-4-F
H CH(CH3)CH2SCH3 CF3 Ph-3-NO2-4-F
H CH(CH3)CH2SCH3 CF3 Ph-3-NO2-4-Cl
H CH(CH3)CH2SCH3 CF3 Ph-2-F-5-NO2
H CH(CH3)CH2SCH3 CF3 Ph-3-CN-4-F
H CH(CH3)CH2SCH3 CF3 Ph-2,3,4-F3
H CH(CH3)CH2SCH3 CF3 Ph-2,3,5-F3
H CH(CH3)CH2SCH3 CF3 Ph-2,4,5-F3
H CH(CH3)CH2SCH3 CF3 Ph-3,4,5-F3
H CH(CH3)CH2SCH3 CF3 Ph-2,3-F2-4-CH3
H CH(CH3)CH2SCH3 CF3 Ph-2,3-F2-4-CF3
H CH(CH3)CH2SCH3 CF3 Ph-3,4-F2-5-CF3
H CH(CH3)CH2SCH3 CF3 Ph-2-F-3-Cl-5-CF3
H CH(CH3)CH2SCH3 CF3 Ph-3,5-Cl2-4-OCH3
H CH(CH3)CH2SCH3 CF3 1-Naph
H CH(CH3)CH2SCH3 CF3 2-Naph
H CH(CH3)CH2SCH3 CF3 (L-1b)Br
H CH(CH3)CH2SCH3 CF3 (L-1c)Cl
H CH(CH3)CH2SCH3 CF3 (L-1c)Br
H CH(CH3)CH2SCH3 CF3 (L-1c)I
H CH(CH3)CH2SCH3 CF3 (L-1c)CF3
H CH(CH3)CH2SCH3 CF3 (L-2b)Br
H CH(CH3)CH2SCH3 CF3 (L-3b)Cl
H CH(CH3)CH2SCH3 CF3 (L-3b)Br
H CH(CH3)CH2SCH3 CF3 (L-3c)F
H CH(CH3)CH2SCH3 CF3 (L-3c)Cl
H CH(CH3)CH2SCH3 CF3 (L-3c)Br
H CH(CH3)CH2SCH3 CF3 (L-3c)I
H CH(CH3)CH2SCH3 CF3 (L-3c)CF3
H CH(CH3)CH2SCH3 CF3 (L-3c)CN
H CH(CH3)CH2SCH3 CF3 L-3d
H CH(CH3)CH2SCH3 CF3 (L-4b)Cl
H CH(CH3)CH2SCH3 CF3 (L-4b)Br
H CH(CH3)CH2SCH3 CF3 (L-4b)CN
H CH(CH3)CH2SCH3 CF3 (L-10b)Cl
H CH(CH3)CH2SCH3 CF3 (L-10b)Br
H CH(CH3)CH2SCH3 CF3 (L-15b)CF3
H CH(CH3)CH2SCH3 CF3 (L-16a)CHF2
H CH(CH3)CH2SCH3 CF3 (L-16a)CF2Br
H CH(CH3)CH2SCH3 CF3 (L-17a)Cl
H CH(CH3)CH2SCH3 CF3 (L-21b)Cl
H CH(CH3)CH2SCH3 CF3 (L-21b)Br
H CH(CH3)CH2SCH3 CF3 (L-21b)I
H CH(CH3)CH2SCH3 CF3 (L-21b)CF3
H CH(CH3)CH2SCH3 CF3 (L-22b)Cl
H CH(CH3)CH2SCH3 CF3 (L-22b)Br
H CH(CH3)CH2SCH3 CF3 (L-23b)Cl
H CH(CH3)CH2SCH3 CF3 (L-23b)Br
H CH(CH3)CH2SCH3 CF3 (L-23c)Cl
H CH(CH3)CH2SCH3 CF3 (L-23c)Br
H CH(CH3)CH2SCH3 CF3 (L-31a)Cl
H CH(CH3)CH2SCH3 CF3 (L-31a)Br
H CH(CH3)CH2SCH3 CF3 (L-45c)F
H CH(CH3)CH2SCH3 CF3 (L-45c)Cl
H CH(CH3)CH2SCH3 CF3 (L-45c)Br
H CH(CH3)CH2SCH3 CF3 (L-45c)I
H CH(CH3)CH2SCH3 CF3 (L-45c)CF3
H CH(CH3)CH2SCH3 CF3 L-45e
H CH(CH3)CH2SCH3 CF3 L-45f
H CH(CH3)CH2SCH3 CF3 (L-46c)F
H CH(CH3)CH2SCH3 CF3 (L-46c)Cl
H CH(CH3)CH2SCH3 CF3 (L-46c)Br
H CH(CH3)CH2SCH3 CF3 (L-46c)I
H CH(CH3)CH2SCH3 CF3 (L-46c)CF3
H CH(CH3)CH2SCH3 CF3 (L-46c)OCH2CF3
H CH(CH3)CH2SCH3 CF3 (L-46c)OCH(CF3)2
H CH(CH3)CH2SCH3 CF3 L-46d
H CH(CH3)CH2SCH3 CF3 L-47a
H CH(CH3)CH2SCH3 CF3 L-47d
H CH(CH3)CH2SCH3 CF3 (L-48b)Br
H CH(CH3)CH2SCH3 CF3 (L-50b)Cl
H CH(CH3)CH2SCH3 CF3 (L-50b)Br
H CH(CH3)CH2SCH3 CF3 (L-51b)Cl
H CH(CH3)CH2SCH3 CF2Cl Ph-4-Cl
H CH(CH3)CH2SCH3 CF2Cl Ph-4-Br
H CH(CH3)CH2SCH3 CF2Cl Ph-4-CF3
H CH(CH3)CH2SCH3 CF2Cl Ph-4-OCF3
H CH(CH3)CH2SCH3 CF2Cl Ph-4-OCF2Br
H CH(CH3)CH2SCH3 CF2Cl Ph-4-OCF2CHFCF3
H CH(CH3)CH2SCH3 CF2Cl Ph-4-OCF2CHFOCF3
H CH(CH3)CH2SCH3 CF2Cl Ph-4-OCF2CHFOCF2CF2CF3
H CH(CH3)CH2SCH3 CF2Cl Ph-4-O(L-45g)
H CH(CH3)CH2SCH3 CF2Cl Ph-3,4-Cl2
H CH(CH3)CH2SCH3 CF2Cl Ph(-3-OCF2O-4-)
H CH(CH3)CH2SCH3 CF2Cl Ph(-3-OCF2CF2O-4-)
H CH(CH3)CH2SCH3 CF2Cl (L-45c)CF3
H CH(CH3)CH2SCH3 CF2Cl L-45f
H CH(CH3)CH2SCH3 CF2Cl (L-46c)CF3
H CH(CH3)CH2SCH3 CF2Cl L-46d
H CH(CH3)CH2SCH3 CFCl2 (L-45c)CF3
H CH(CH3)CH2SCH3 CF2Br Ph-4-Cl
H CH(CH3)CH2SCH3 CF2Br Ph-4-Br
H CH(CH3)CH2SCH3 CF2Br Ph-4-CF3
H CH(CH3)CH2SCH3 CF2Br Ph-4-OCF3
H CH(CH3)CH2SCH3 CF2Br Ph-4-OCF2Br
H CH(CH3)CH2SCH3 CF2Br Ph-4-OCF2CHFCF3
H CH(CH3)CH2SCH3 CF2Br Ph-4-OCF2CHFOCF3
H CH(CH3)CH2SCH3 CF2Br Ph-4-OCF2CHFOCF2CF2CF3
H CH(CH3)CH2SCH3 CF2Br Ph-4-O(L-45g)
H CH(CH3)CH2SCH3 CF2Br Ph-3,4-Cl2
H CH(CH3)CH2SCH3 CF2Br Ph(-3-OCF2O-4-)
H CH(CH3)CH2SCH3 CF2Br Ph(-3-OCF2CF2O-4-)
H CH(CH3)CH2SCH3 CF2Br (L-45c)CF3
H CH(CH3)CH2SCH3 CF2Br L-45f
H CH(CH3)CH2SCH3 CF2Br (L-46c)CF3
H CH(CH3)CH2SCH3 CF2Br L-46d
H CH(CH3)CH2SCH3 CFClBr Ph-4-Br
H CH(CH3)CH2SCH3 CFBr2 Ph-4-CF3
H CH(CH3)CH2SCH3 CF2CHF2 Ph-4-OCF3
H CH(CH3)CH2SCH3 CF2CF3 Ph-4-Cl
H CH(CH3)CH2SCH3 CF2CF3 Ph-4-Br
H CH(CH3)CH2SCH3 CF2CF3 Ph-4-CF3
H CH(CH3)CH2SCH3 CF2CF3 Ph-4-OCF3
H CH(CH3)CH2SCH3 CF2CF3 Ph-4-OCF2Br
H CH(CH3)CH2SCH3 CF2CF3 Ph-4-OCF2CHFCF3
H CH(CH3)CH2SCH3 CF2CF3 Ph-4-OCF2CHFOCF3
H CH(CH3)CH2SCH3 CF2CF3 Ph-4-OCF2CHFOCF2CF2CF3
H CH(CH3)CH2SCH3 CF2CF3 Ph-4-O(L-45g)
H CH(CH3)CH2SCH3 CF2CF3 Ph-3,4-Cl2
H CH(CH3)CH2SCH3 CF2CF3 Ph(-3-OCF2O-4-)
H CH(CH3)CH2SCH3 CF2CF3 Ph(-3-OCF2CF2O-4-)
H CH(CH3)CH2SCH3 CF2CF3 (L-45c)CF3
H CH(CH3)CH2SCH3 CF2CF3 L-45f
H CH(CH3)CH2SCH3 CF2CF3 (L-46c)CF3
H CH(CH3)CH2SCH3 CF2CF3 L-46d
H CH(CH3)CH2SCH3 CF2CF2Cl (L-45c)CF3
H CH(CH3)CH2SCH3 CFClCF3 Ph-4-Br
H CH(CH3)CH2SCH3 CFClCF2Cl Ph-4-CF3
H CH(CH3)CH2SCH3 CF2CF2Br Ph-4-OCF3
H CH(CH3)CH2SCH3 CFBrCF3 (L-45c)CF3
H CH(CH3)CH2SCH3 CF2CHFCF3 Ph-4-Br
H CH(CH3)CH2SCH3 CF2CF2CF3 Ph-4-Cl
H CH(CH3)CH2SCH3 CF2CF2CF3 Ph-4-Br
H CH(CH3)CH2SCH3 CF2CF2CF3 Ph-4-CF3
H CH(CH3)CH2SCH3 CF2CF2CF3 Ph-4-OCF3
H CH(CH3)CH2SCH3 CF2CF2CF3 Ph-4-OCF2Br
H CH(CH3)CH2SCH3 CF2CF2CF3 Ph-4-OCF2CHFCF3
H CH(CH3)CH2SCH3 CF2CF2CF3 Ph-4-OCF2CHFOCF3
H CH(CH3)CH2SCH3 CF2CF2CF3 Ph-4-OCF2CHFOCF2CF2CF3
H CH(CH3)CH2SCH3 CF2CF2CF3 Ph-4-O(L-45g)
H CH(CH3)CH2SCH3 CF2CF2CF3 Ph-3,4-Cl2
H CH(CH3)CH2SCH3 CF2CF2CF3 Ph(-3-OCF2O-4-)
H CH(CH3)CH2SCH3 CF2CF2CF3 Ph(-3-OCF2CF2O-4-)
H CH(CH3)CH2SCH3 CF2CF2CF3 (L-45c)CF3
H CH(CH3)CH2SCH3 CF2CF2CF3 L-45f
H CH(CH3)CH2SCH3 CF2CF2CF3 (L-46c)CF3
H CH(CH3)CH2SCH3 CF2CF2CF3 L-46d
H CH(CH3)CH2SCH3 CF(CF3)2 Ph-4-CF3
H CH(CH3)CH2SCH3 CF2CF2CF2CF3 Ph-4-OCF3
H CH(CH3)CH2SCH3 T-1 (L-45c)CF3
H CH(CH3)CH2SCH3 T-2 Ph-4-Br
H CH(CH3)CH2SCH3 CH2OCH3 Ph-4-CF3
H CH(CH3)CH2SCH3 CH2OEt Ph-4-OCF3
H CH(CH3)CH2SCH3 CH2OCH2CF3 (L-45c)CF3
H CH(CH3)CH2SCH3 CH2OCH(CF3)2 Ph-4-Br
H CH(CH3)CH2SCH3 CF2OCH3 Ph-4-Cl
H CH(CH3)CH2SCH3 CF2OCH3 Ph-4-Br
H CH(CH3)CH2SCH3 CF2OCH3 Ph-4-CF3
H CH(CH3)CH2SCH3 CF2OCH3 Ph-4-OCF3
H CH(CH3)CH2SCH3 CF2OCH3 Ph-4-OCF2Br
H CH(CH3)CH2SCH3 CF2OCH3 Ph-4-OCF2CHFCF3
H CH(CH3)CH2SCH3 CF2OCH3 Ph-4-OCF2CHFOCF3
H CH(CH3)CH2SCH3 CF2OCH3 Ph-4-OCF2CHFOCF2CF2CF3
H CH(CH3)CH2SCH3 CF2OCH3 Ph-4-O(L-45g)
H CH(CH3)CH2SCH3 CF2OCH3 Ph-3,4-Cl2
H CH(CH3)CH2SCH3 CF2OCH3 Ph(-3-OCF2O-4-)
H CH(CH3)CH2SCH3 CF2OCH3 Ph(-3-OCF2CF2O-4-)
H CH(CH3)CH2SCH3 CF2OCH3 (L-45c)CF3
H CH(CH3)CH2SCH3 CF2OCH3 L-45f
H CH(CH3)CH2SCH3 CF2OCH3 (L-46c)CF3
H CH(CH3)CH2SCH3 CF2OCH3 L-46d
H CH(CH3)CH2SCH3 CH2SCH3 Ph-4-CF3
H CH(CH3)CH2SCH3 CH2SO2CH3 Ph-4-OCF3
H CH(CH3)CH2SCH3 CH2SCF3 (L-45c)CF3
H CH(CH3)CH2SCH3 CF2SCH3 Ph-4-Cl
H CH(CH3)CH2SCH3 CF2SCH3 Ph-4-Br
H CH(CH3)CH2SCH3 CF2SCH3 Ph-4-CF3
H CH(CH3)CH2SCH3 CF2SCH3 Ph-4-OCF3
H CH(CH3)CH2SCH3 CF2SCH3 Ph-4-OCF2Br
H CH(CH3)CH2SCH3 CF2SCH3 Ph-4-OCF2CHFCF3
H CH(CH3)CH2SCH3 CF2SCH3 Ph-4-OCF2CHFOCF3
H CH(CH3)CH2SCH3 CF2SCH3 Ph-4-OCF2CHFOCF2CF2CF3
H CH(CH3)CH2SCH3 CF2SCH3 Ph-4-O(L-45g)
H CH(CH3)CH2SCH3 CF2SCH3 Ph-3,4-Cl2
H CH(CH3)CH2SCH3 CF2SCH3 Ph(-3-OCF2O-4-)
H CH(CH3)CH2SCH3 CF2SCH3 Ph(-3-OCF2CF2O-4-)
H CH(CH3)CH2SCH3 CF2SCH3 (L-45c)CF3
H CH(CH3)CH2SCH3 CF2SCH3 L-45f
H CH(CH3)CH2SCH3 CF2SCH3 (L-46c)CF3
H CH(CH3)CH2SCH3 CF2SCH3 L-46d
H CH(CH3)CH2SCH3 CF2SEt Ph-4-Br
H CH(CH3)CH2SCH3 CF2SPr-n Ph-4-CF3
H CH(CH3)CH2SCH3 CF2SPr-i Ph-4-OCF3
H CH(CH3)CH2SCH3 CF2SCH2Ph (L-45c)CF3
H CH(CH3)CH2SCH3 CF2SPh Ph-4-Br
H CH(CH3)CH2SCH3 CF2C(O)OEt Ph-4-CF3
H CH(CH3)CH2SCH3 CF2SO2N(CH3)2 Ph-4-OCF3
H CH(CH3)CH2SCH3 C(O)OEt (L-45c)CF3
H CH(CH3)CH2SCH3 C(O)SEt Ph-4-Br
CH3 CH(CH3)CH2SCH3 CF3 Ph-4-CF3
Et CH(CH3)CH2SCH3 CF3 Ph-4-OCF3
H CH(CH3)CH2S(O)CH3 CH3 Ph-4-Br
H CH(CH3)CH2S(O)CH3 CH3 Ph-4-CF3
H CH(CH3)CH2S(O)CH3 CH3 Ph-4-OCF3
H CH(CH3)CH2S(O)CH3 CH3 (L-45c)CF3
H CH(CH3)CH2S(O)CH3 CF3 CH2O(Ph-4-Cl)
H CH(CH3)CH2S(O)CH3 CF3 CH2O(Ph-4-Br)
H CH(CH3)CH2S(O)CH3 CF3 CH2O(Ph-4-CF3)
H CH(CH3)CH2S(O)CH3 CF3 CH2O(Ph-4-OCF3)
H CH(CH3)CH2S(O)CH3 CF3 CF2O(Ph-4-Cl)
H CH(CH3)CH2S(O)CH3 CF3 CF2O(Ph-4-Br)
H CH(CH3)CH2S(O)CH3 CF3 CF2O(Ph-4-CF3)
H CH(CH3)CH2S(O)CH3 CF3 CF2O(Ph-4-OCF3)
H CH(CH3)CH2S(O)CH3 CF3 CH=CH(Ph-4-F)
H CH(CH3)CH2S(O)CH3 CF3 CH=CH(Ph-4-Cl)
H CH(CH3)CH2S(O)CH3 CF3 CH=CH(Ph-4-Br)
H CH(CH3)CH2S(O)CH3 CF3 CH=CH(Ph-4-CF3)
H CH(CH3)CH2S(O)CH3 CF3 CH=CH(Ph-4-OCF3)
H CH(CH3)CH2S(O)CH3 CF3 CH=CH(Ph-4-SCH3)
H CH(CH3)CH2S(O)CH3 CF3 CH=CH(Ph-4-SO2CH3)
H CH(CH3)CH2S(O)CH3 CF3 CH=CH(Ph-3,4-Cl2)
H CH(CH3)CH2S(O)CH3 CF3 Ph-4-F
H CH(CH3)CH2S(O)CH3 CF3 Ph-2-Cl
H CH(CH3)CH2S(O)CH3 CF3 Ph-3-Cl
H CH(CH3)CH2S(O)CH3 CF3 Ph-4-Cl
H CH(CH3)CH2S(O)CH3 CF3 Ph-4-Br
H CH(CH3)CH2S(O)CH3 CF3 Ph-4-I
H CH(CH3)CH2S(O)CH3 CF3 Ph-4-CF3
H CH(CH3)CH2S(O)CH3 CF3 Ph-4-OCHF2
H CH(CH3)CH2S(O)CH3 CF3 Ph-4-OCF3
H CH(CH3)CH2S(O)CH3 CF3 Ph-4-OCF2Br
H CH(CH3)CH2S(O)CH3 CF3 Ph-4-OCH2CF3
H CH(CH3)CH2S(O)CH3 CF3 Ph-4-OCF2CHF2
H CH(CH3)CH2S(O)CH3 CF3 Ph-4-OCF2CHFCl
H CH(CH3)CH2S(O)CH3 CF3 Ph-4-OCF2CHFCF3
H CH(CH3)CH2S(O)CH3 CF3 Ph-4-OCF2CHFOCF3
H CH(CH3)CH2S(O)CH3 CF3 Ph-4-OCF2CHFOCF2CF2CF3
H CH(CH3)CH2S(O)CH3 CF3 Ph-4-OSO2CH3
H CH(CH3)CH2S(O)CH3 CF3 Ph-4-OSO2CF3
H CH(CH3)CH2S(O)CH3 CF3 Ph-4-O(L-45e)
H CH(CH3)CH2S(O)CH3 CF3 Ph-2,4-F2
H CH(CH3)CH2S(O)CH3 CF3 Ph-3,4-F2
H CH(CH3)CH2S(O)CH3 CF3 Ph-3-Cl-4-F
H CH(CH3)CH2S(O)CH3 CF3 Ph-2-F-4-Cl
H CH(CH3)CH2S(O)CH3 CF3 Ph-3-F-4-Cl
H CH(CH3)CH2S(O)CH3 CF3 Ph-2,4-Cl2
H CH(CH3)CH2S(O)CH3 CF3 Ph-3,4-Cl2
H CH(CH3)CH2S(O)CH3 CF3 Ph-3,5-Cl2
H CH(CH3)CH2S(O)CH3 CF3 Ph-3-Br-4-F
H CH(CH3)CH2S(O)CH3 CF3 Ph-2-F-4-Br
H CH(CH3)CH2S(O)CH3 CF3 Ph-3,4-Br2
H CH(CH3)CH2S(O)CH3 CF3 Ph-3-CH3-4-F
H CH(CH3)CH2S(O)CH3 CF3 Ph-3-CF3-4-F
H CH(CH3)CH2S(O)CH3 CF3 Ph-3-CF3-4-Cl
H CH(CH3)CH2S(O)CH3 CF3 Ph-2-F-4-CF3
H CH(CH3)CH2S(O)CH3 CF3 Ph-3-F-4-CF3
H CH(CH3)CH2S(O)CH3 CF3 Ph-2-Cl-4-CF3
H CH(CH3)CH2S(O)CH3 CF3 Ph-3-F-4-OCHF2
H CH(CH3)CH2S(O)CH3 CF3 Ph-3-Cl-4-OCHF2
H CH(CH3)CH2S(O)CH3 CF3 Ph-3-Br-4-OCHF2
H CH(CH3)CH2S(O)CH3 CF3 Ph-3-F-4-OCF3
H CH(CH3)CH2S(O)CH3 CF3 Ph-3-Cl-4-OCF3
H CH(CH3)CH2S(O)CH3 CF3 Ph-3-Br-4-OCF3
H CH(CH3)CH2S(O)CH3 CF3 Ph-3-F-4-OCF2Br
H CH(CH3)CH2S(O)CH3 CF3 Ph-3-Cl-4-OCF2Br
H CH(CH3)CH2S(O)CH3 CF3 Ph-3-Br-4-OCF2Br
H CH(CH3)CH2S(O)CH3 CF3 Ph-3-F-4-OCF2CHF2
H CH(CH3)CH2S(O)CH3 CF3 Ph-3-Cl-4-OCF2CHF2
H CH(CH3)CH2S(O)CH3 CF3 Ph-3-Br-4-OCF2CHF2
H CH(CH3)CH2S(O)CH3 CF3 Ph-3-F-4-OCF2CHFCl
H CH(CH3)CH2S(O)CH3 CF3 Ph-3-Cl-4-OCF2CHFCl
H CH(CH3)CH2S(O)CH3 CF3 Ph-3-Br-4-OCF2CHFCl
H CH(CH3)CH2S(O)CH3 CF3 Ph-3-F-4-OCF2CHFCF3
H CH(CH3)CH2S(O)CH3 CF3 Ph-3-Cl-4-OCF2CHFCF3
H CH(CH3)CH2S(O)CH3 CF3 Ph-3-Br-4-OCF2CHFCF3
H CH(CH3)CH2S(O)CH3 CF3 Ph-3-F-4-OCF2CHFOCF3
H CH(CH3)CH2S(O)CH3 CF3 Ph-3-Cl-4-OCF2CHFOCF3
H CH(CH3)CH2S(O)CH3 CF3 Ph-3-Br-4-OCF2CHFOCF3
H CH(CH3)CH2S(O)CH3 CF3 Ph-3-CH3-4-OCF2CHFOCF3
H CH(CH3)CH2S(O)CH3 CF3 Ph-3-F-4-OCF2CHFOCF2CF2CF3
H CH(CH3)CH2S(O)CH3 CF3 Ph-3-Cl-4-OCF2CHFOCF2CF2CF3
H CH(CH3)CH2S(O)CH3 CF3 Ph-3-Br-4-OCF2CHFOCF2CF2CF3
H CH(CH3)CH2S(O)CH3 CF3 Ph(-3-OCF2O-4-)
H CH(CH3)CH2S(O)CH3 CF3 Ph(-3-OCF2CF2O-4-)
H CH(CH3)CH2S(O)CH3 CF3 Ph-3,4-F2-5-CF3
H CH(CH3)CH2S(O)CH3 CF3 2-Naph
H CH(CH3)CH2S(O)CH3 CF3 (L-1b)Br
H CH(CH3)CH2S(O)CH3 CF3 (L-1c)Cl
H CH(CH3)CH2S(O)CH3 CF3 (L-1c)Br
H CH(CH3)CH2S(O)CH3 CF3 (L-1c)CF3
H CH(CH3)CH2S(O)CH3 CF3 (L-2b)Br
H CH(CH3)CH2S(O)CH3 CF3 (L-3b)Cl
H CH(CH3)CH2S(O)CH3 CF3 (L-3b)Br
H CH(CH3)CH2S(O)CH3 CF3 (L-3c)Cl
H CH(CH3)CH2S(O)CH3 CF3 (L-3c)Br
H CH(CH3)CH2S(O)CH3 CF3 (L-3c)CF3
H CH(CH3)CH2S(O)CH3 CF3 L-3d
H CH(CH3)CH2S(O)CH3 CF3 (L-4b)Cl
H CH(CH3)CH2S(O)CH3 CF3 (L-4b)Br
H CH(CH3)CH2S(O)CH3 CF3 (L-10b)Cl
H CH(CH3)CH2S(O)CH3 CF3 (L-10b)Br
H CH(CH3)CH2S(O)CH3 CF3 (L-15b)CF3
H CH(CH3)CH2S(O)CH3 CF3 (L-16a)CHF2
H CH(CH3)CH2S(O)CH3 CF3 (L-16a)CF2Br
H CH(CH3)CH2S(O)CH3 CF3 (L-17a)Cl
H CH(CH3)CH2S(O)CH3 CF3 (L-21b)Cl
H CH(CH3)CH2S(O)CH3 CF3 (L-21b)Br
H CH(CH3)CH2S(O)CH3 CF3 (L-21b)CF3
H CH(CH3)CH2S(O)CH3 CF3 (L-22b)Cl
H CH(CH3)CH2S(O)CH3 CF3 (L-22b)Br
H CH(CH3)CH2S(O)CH3 CF3 (L-23b)Cl
H CH(CH3)CH2S(O)CH3 CF3 (L-23b)Br
H CH(CH3)CH2S(O)CH3 CF3 (L-23c)Cl
H CH(CH3)CH2S(O)CH3 CF3 (L-23c)Br
H CH(CH3)CH2S(O)CH3 CF3 (L-31a)Cl
H CH(CH3)CH2S(O)CH3 CF3 (L-31a)Br
H CH(CH3)CH2S(O)CH3 CF3 (L-45c)F
H CH(CH3)CH2S(O)CH3 CF3 (L-45c)Cl
H CH(CH3)CH2S(O)CH3 CF3 (L-45c)Br
H CH(CH3)CH2S(O)CH3 CF3 (L-45c)CF3
H CH(CH3)CH2S(O)CH3 CF3 L-45e
H CH(CH3)CH2S(O)CH3 CF3 L-45f
H CH(CH3)CH2S(O)CH3 CF3 (L-46c)F
H CH(CH3)CH2S(O)CH3 CF3 (L-46c)Cl
H CH(CH3)CH2S(O)CH3 CF3 (L-46c)Br
H CH(CH3)CH2S(O)CH3 CF3 (L-46c)CF3
H CH(CH3)CH2S(O)CH3 CF3 L-46d
H CH(CH3)CH2S(O)CH3 CF3 L-47a
H CH(CH3)CH2S(O)CH3 CF3 L-47d
H CH(CH3)CH2S(O)CH3 CF3 (L-48b)Br
H CH(CH3)CH2S(O)CH3 CF3 (L-50b)Cl
H CH(CH3)CH2S(O)CH3 CF3 (L-50b)Br
H CH(CH3)CH2S(O)CH3 CF3 (L-51b)Cl
H CH(CH3)CH2SO2CH3 CH3 CF2O(Ph-4-Cl)
H CH(CH3)CH2SO2CH3 CH3 CH=CH(Ph-4-Cl)
H CH(CH3)CH2SO2CH3 CH3 CH=CH(Ph-4-OCF3)
H CH(CH3)CH2SO2CH3 CH3 CH=CH(Ph-3,4-Cl2)
H CH(CH3)CH2SO2CH3 CH3 Ph-4-F
H CH(CH3)CH2SO2CH3 CH3 Ph-4-Cl
H CH(CH3)CH2SO2CH3 CH3 Ph-4-Br
H CH(CH3)CH2SO2CH3 CH3 Ph-4-I
H CH(CH3)CH2SO2CH3 CH3 Ph-4-CF3
H CH(CH3)CH2SO2CH3 CH3 Ph-4-OCHF2
H CH(CH3)CH2SO2CH3 CH3 Ph-4-OCF3
H CH(CH3)CH2SO2CH3 CH3 Ph-4-OCF2Br
H CH(CH3)CH2SO2CH3 CH3 Ph-4-OCF2CHF2
H CH(CH3)CH2SO2CH3 CH3 Ph-4-OCF2CHFCl
H CH(CH3)CH2SO2CH3 CH3 Ph-4-OCF2CHFCF3
H CH(CH3)CH2SO2CH3 CH3 Ph-4-OCF2CHFOCF3
H CH(CH3)CH2SO2CH3 CH3 Ph-4-OCF2CHFOCF2CF2CF3
H CH(CH3)CH2SO2CH3 CH3 Ph-4-O(L-45g)
H CH(CH3)CH2SO2CH3 CH3 Ph-3,4-Cl2
H CH(CH3)CH2SO2CH3 CH3 Ph(-3-OCF2O-4-)
H CH(CH3)CH2SO2CH3 CH3 Ph(-3-OCF2CF2O-4-)
H CH(CH3)CH2SO2CH3 CH3 (L-45c)Cl
H CH(CH3)CH2SO2CH3 CH3 (L-45c)Br
H CH(CH3)CH2SO2CH3 CH3 (L-45c)CF3
H CH(CH3)CH2SO2CH3 CH3 L-45e
H CH(CH3)CH2SO2CH3 CH3 L-45f
H CH(CH3)CH2SO2CH3 CH3 (L-46c)Cl
H CH(CH3)CH2SO2CH3 CH3 (L-46c)Br
H CH(CH3)CH2SO2CH3 CH3 (L-46c)CF3
H CH(CH3)CH2SO2CH3 CH3 L-46d
H CH(CH3)CH2SO2CH3 Et Ph-4-Cl
H CH(CH3)CH2SO2CH3 Et Ph-4-Br
H CH(CH3)CH2SO2CH3 Et Ph-4-CF3
H CH(CH3)CH2SO2CH3 Et Ph-4-OCF3
H CH(CH3)CH2SO2CH3 Et Ph-4-OCF2Br
H CH(CH3)CH2SO2CH3 Et Ph-4-OCF2CHFCF3
H CH(CH3)CH2SO2CH3 Et Ph-4-OCF2CHFOCF3
H CH(CH3)CH2SO2CH3 Et Ph-4-OCF2CHFOCF2CF2CF3
H CH(CH3)CH2SO2CH3 Et Ph-4-O(L-45g)
H CH(CH3)CH2SO2CH3 Et Ph-3,4-Cl2
H CH(CH3)CH2SO2CH3 Et Ph(-3-OCF2O-4-)
H CH(CH3)CH2SO2CH3 Et Ph(-3-OCF2CF2O-4-)
H CH(CH3)CH2SO2CH3 Et (L-45c)CF3
H CH(CH3)CH2SO2CH3 n-Pr Ph-4-Br
H CH(CH3)CH2SO2CH3 n-Pr Ph-4-CF3
H CH(CH3)CH2SO2CH3 n-Pr Ph-4-OCF3
H CH(CH3)CH2SO2CH3 n-Pr (L-45c)CF3
H CH(CH3)CH2SO2CH3 i-Pr Ph-4-Br
H CH(CH3)CH2SO2CH3 i-Pr Ph-4-CF3
H CH(CH3)CH2SO2CH3 i-Pr Ph-4-OCF3
H CH(CH3)CH2SO2CH3 i-Pr (L-45c)CF3
H CH(CH3)CH2SO2CH3 c-Pr Ph-4-Br
H CH(CH3)CH2SO2CH3 c-Pr Ph-4-CF3
H CH(CH3)CH2SO2CH3 c-Pr Ph-4-OCF3
H CH(CH3)CH2SO2CH3 c-Pr (L-45c)CF3
H CH(CH3)CH2SO2CH3 n-Bu (L-45c)CF3
H CH(CH3)CH2SO2CH3 CH2F Ph-4-Br
H CH(CH3)CH2SO2CH3 CH2Cl Ph-4-CF3
H CH(CH3)CH2SO2CH3 CH2Br Ph-4-OCF3
H CH(CH3)CH2SO2CH3 CHF2 Ph-4-Cl
H CH(CH3)CH2SO2CH3 CHF2 Ph-4-Br
H CH(CH3)CH2SO2CH3 CHF2 Ph-4-CF3
H CH(CH3)CH2SO2CH3 CHF2 Ph-4-OCF3
H CH(CH3)CH2SO2CH3 CHF2 Ph-4-OCF2Br
H CH(CH3)CH2SO2CH3 CHF2 Ph-4-OCF2CHFCF3
H CH(CH3)CH2SO2CH3 CHF2 Ph-4-OCF2CHFOCF3
H CH(CH3)CH2SO2CH3 CHF2 Ph-4-OCF2CHFOCF2CF2CF3
H CH(CH3)CH2SO2CH3 CHF2 Ph-4-O(L-45g)
H CH(CH3)CH2SO2CH3 CHF2 Ph-3,4-Cl2
H CH(CH3)CH2SO2CH3 CHF2 Ph(-3-OCF2O-4-)
H CH(CH3)CH2SO2CH3 CHF2 Ph(-3-OCF2CF2O-4-)
H CH(CH3)CH2SO2CH3 CHF2 (L-45c)CF3
H CH(CH3)CH2SO2CH3 CHF2 L-45f
H CH(CH3)CH2SO2CH3 CHF2 (L-46c)CF3
H CH(CH3)CH2SO2CH3 CHF2 L-46d
H CH(CH3)CH2SO2CH3 CHFCl (L-45c)CF3
H CH(CH3)CH2SO2CH3 CHFBr Ph-4-Br
H CH(CH3)CH2SO2CH3 CF3 c-Pr
H CH(CH3)CH2SO2CH3 CF3 c-Bu
H CH(CH3)CH2SO2CH3 CF3 c-Pen
H CH(CH3)CH2SO2CH3 CF3 c-Hex
H CH(CH3)CH2SO2CH3 CF3 T-1
H CH(CH3)CH2SO2CH3 CF3 T-2
H CH(CH3)CH2SO2CH3 CF3 T-3
H CH(CH3)CH2SO2CH3 CF3 T-4
H CH(CH3)CH2SO2CH3 CF3 T-5
H CH(CH3)CH2SO2CH3 CF3 CH2OCH3
H CH(CH3)CH2SO2CH3 CF3 CH2OEt
H CH(CH3)CH2SO2CH3 CF3 CH2OPr-n
H CH(CH3)CH2SO2CH3 CF3 CH2OPr-i
H CH(CH3)CH2SO2CH3 CF3 CH2OBu-n
H CH(CH3)CH2SO2CH3 CF3 CH2OC(O)(Ph-2-Cl)
H CH(CH3)CH2SO2CH3 CF3 CH2OC(O)(Ph-3-Cl)
H CH(CH3)CH2SO2CH3 CF3 CH2OC(O)(Ph-4-Cl)
H CH(CH3)CH2SO2CH3 CF3 CH2OPh
H CH(CH3)CH2SO2CH3 CF3 CH2O(Ph-2-F)
H CH(CH3)CH2SO2CH3 CF3 CH2O(Ph-3-F)
H CH(CH3)CH2SO2CH3 CF3 CH2O(Ph-4-F)
H CH(CH3)CH2SO2CH3 CF3 CH2O(Ph-2-Cl)
H CH(CH3)CH2SO2CH3 CF3 CH2O(Ph-3-Cl)
H CH(CH3)CH2SO2CH3 CF3 CH2O(Ph-4-Cl)
H CH(CH3)CH2SO2CH3 CF3 CH2O(Ph-2-Br)
H CH(CH3)CH2SO2CH3 CF3 CH2O(Ph-3-Br)
H CH(CH3)CH2SO2CH3 CF3 CH2O(Ph-4-Br)
H CH(CH3)CH2SO2CH3 CF3 CH2O(Ph-2-CF3)
H CH(CH3)CH2SO2CH3 CF3 CH2O(Ph-3-CF3)
H CH(CH3)CH2SO2CH3 CF3 CH2O(Ph-4-CF3)
H CH(CH3)CH2SO2CH3 CF3 CH2O(Ph-2-OCF3)
H CH(CH3)CH2SO2CH3 CF3 CH2O(Ph-3-OCF3)
H CH(CH3)CH2SO2CH3 CF3 CH2O(Ph-4-OCF3)
H CH(CH3)CH2SO2CH3 CF3 CF2OPh
H CH(CH3)CH2SO2CH3 CF3 CF2O(Ph-2-F)
H CH(CH3)CH2SO2CH3 CF3 CF2O(Ph-3-F)
H CH(CH3)CH2SO2CH3 CF3 CF2O(Ph-4-F)
H CH(CH3)CH2SO2CH3 CF3 CF2O(Ph-2-Cl)
H CH(CH3)CH2SO2CH3 CF3 CF2O(Ph-3-Cl)
H CH(CH3)CH2SO2CH3 CF3 CF2O(Ph-4-Cl)
H CH(CH3)CH2SO2CH3 CF3 CF2O(Ph-2-Br)
H CH(CH3)CH2SO2CH3 CF3 CF2O(Ph-3-Br)
H CH(CH3)CH2SO2CH3 CF3 CF2O(Ph-4-Br)
H CH(CH3)CH2SO2CH3 CF3 CF2O(Ph-2-CF3)
H CH(CH3)CH2SO2CH3 CF3 CF2O(Ph-3-CF3)
H CH(CH3)CH2SO2CH3 CF3 CF2O(Ph-4-CF3)
H CH(CH3)CH2SO2CH3 CF3 CF2O(Ph-2-OCF3)
H CH(CH3)CH2SO2CH3 CF3 CF2O(Ph-3-OCF3)
H CH(CH3)CH2SO2CH3 CF3 CF2O(Ph-4-OCF3)
H CH(CH3)CH2SO2CH3 CF3 CH2S(Ph-2-Cl)
H CH(CH3)CH2SO2CH3 CF3 CH2S(Ph-3-Cl)
H CH(CH3)CH2SO2CH3 CF3 CH2S(Ph-4-Cl)
H CH(CH3)CH2SO2CH3 CF3 CH2SO2(Ph-2-Cl)
H CH(CH3)CH2SO2CH3 CF3 CH2SO2(Ph-3-Cl)
H CH(CH3)CH2SO2CH3 CF3 CH2SO2(Ph-4-Cl)
H CH(CH3)CH2SO2CH3 CF3 CH2N(CH3)2
H CH(CH3)CH2SO2CH3 CF3 CH2NH(Ph-2-Cl)
H CH(CH3)CH2SO2CH3 CF3 CH2NH(Ph-3-Cl)
H CH(CH3)CH2SO2CH3 CF3 CH2NH(Ph-4-Cl)
H CH(CH3)CH2SO2CH3 CF3 CF2C(O)OEt
H CH(CH3)CH2SO2CH3 CF3 CH2(L-5a)
H CH(CH3)CH2SO2CH3 CF3 CH2(L-14a)
H CH(CH3)CH2SO2CH3 CF3 CH2(L-24a)
H CH(CH3)CH2SO2CH3 CF3 CH2(L-36a)
H CH(CH3)CH2SO2CH3 CF3 CH2CH2Ph
H CH(CH3)CH2SO2CH3 CF3 CH2CH2(Ph-2-Cl)
H CH(CH3)CH2SO2CH3 CF3 CH2CH2(Ph-3-Cl)
H CH(CH3)CH2SO2CH3 CF3 CH2CH2(Ph-4-Cl)
H CH(CH3)CH2SO2CH3 CF3 T-22
H CH(CH3)CH2SO2CH3 CF3 T-23
H CH(CH3)CH2SO2CH3 CF3 T-24
H CH(CH3)CH2SO2CH3 CF3 C(O)OEt
H CH(CH3)CH2SO2CH3 CF3 C(O)OBu-t
H CH(CH3)CH2SO2CH3 CF3 C(O)OCH2CF3
H CH(CH3)CH2SO2CH3 CF3 CH=CH(Ph-2-F)
H CH(CH3)CH2SO2CH3 CF3 CH=CH(Ph-3-F)
H CH(CH3)CH2SO2CH3 CF3 CH=CH(Ph-4-F)
H CH(CH3)CH2SO2CH3 CF3 CH=CH(Ph-2-Cl)
H CH(CH3)CH2SO2CH3 CF3 CH=CH(Ph-3-Cl)
H CH(CH3)CH2SO2CH3 CF3 CH=CH(Ph-4-Cl)
H CH(CH3)CH2SO2CH3 CF3 CH=CH(Ph-2-Br)
H CH(CH3)CH2SO2CH3 CF3 CH=CH(Ph-3-Br)
H CH(CH3)CH2SO2CH3 CF3 CH=CH(Ph-4-Br)
H CH(CH3)CH2SO2CH3 CF3 CH=CH(Ph-2-CF3)
H CH(CH3)CH2SO2CH3 CF3 CH=CH(Ph-3-CF3)
H CH(CH3)CH2SO2CH3 CF3 CH=CH(Ph-4-CF3)
H CH(CH3)CH2SO2CH3 CF3 CH=CH(Ph-2-OCF3)
H CH(CH3)CH2SO2CH3 CF3 CH=CH(Ph-3-OCF3)
H CH(CH3)CH2SO2CH3 CF3 CH=CH(Ph-4-OCF3)
H CH(CH3)CH2SO2CH3 CF3 CH=CH(Ph-2-SCH3)
H CH(CH3)CH2SO2CH3 CF3 CH=CH(Ph-3-SCH3)
H CH(CH3)CH2SO2CH3 CF3 CH=CH(Ph-4-SCH3)
H CH(CH3)CH2SO2CH3 CF3 CH=CH(Ph-2-SO2CH3)
H CH(CH3)CH2SO2CH3 CF3 CH=CH(Ph-3-SO2CH3)
H CH(CH3)CH2SO2CH3 CF3 CH=CH(Ph-4-SO2CH3)
H CH(CH3)CH2SO2CH3 CF3 CH=CH(Ph-3,4-F2)
H CH(CH3)CH2SO2CH3 CF3 CH=CH(Ph-3-F-4-Cl)
H CH(CH3)CH2SO2CH3 CF3 CH=CH(Ph-3,4-Cl2)
H CH(CH3)CH2SO2CH3 CF3 CH=CH(Ph-3,4-Br2)
H CH(CH3)CH2SO2CH3 CF3 CH=CH(Ph-3-F-4-CF3)
H CH(CH3)CH2SO2CH3 CF3 CH=CH(Ph-3-Cl-4-OCF3)
H CH(CH3)CH2SO2CH3 CF3 CH=CH[Ph(-3-OCF2O-4-)]
H CH(CH3)CH2SO2CH3 CF3 Ph
H CH(CH3)CH2SO2CH3 CF3 Ph-2-F
H CH(CH3)CH2SO2CH3 CF3 Ph-3-F
H CH(CH3)CH2SO2CH3 CF3 Ph-4-F
H CH(CH3)CH2SO2CH3 CF3 Ph-2-Cl
H CH(CH3)CH2SO2CH3 CF3 Ph-3-Cl
H CH(CH3)CH2SO2CH3 CF3 Ph-4-Cl
H CH(CH3)CH2SO2CH3 CF3 Ph-2-Br
H CH(CH3)CH2SO2CH3 CF3 Ph-3-Br
H CH(CH3)CH2SO2CH3 CF3 Ph-4-Br
H CH(CH3)CH2SO2CH3 CF3 Ph-4-I
H CH(CH3)CH2SO2CH3 CF3 Ph-4-Bu-t
H CH(CH3)CH2SO2CH3 CF3 Ph-2-CF3
H CH(CH3)CH2SO2CH3 CF3 Ph-3-CF3
H CH(CH3)CH2SO2CH3 CF3 Ph-4-CF3
H CH(CH3)CH2SO2CH3 CF3 Ph-4-OCH3
H CH(CH3)CH2SO2CH3 CF3 Ph-4-OCHF2
H CH(CH3)CH2SO2CH3 CF3 Ph-2-OCF3
H CH(CH3)CH2SO2CH3 CF3 Ph-3-OCF3
H CH(CH3)CH2SO2CH3 CF3 Ph-4-OCF3
H CH(CH3)CH2SO2CH3 CF3 Ph-4-OCF2Br
H CH(CH3)CH2SO2CH3 CF3 Ph-4-OCH2CF3
H CH(CH3)CH2SO2CH3 CF3 Ph-4-OCF2CHF2
H CH(CH3)CH2SO2CH3 CF3 Ph-4-OCF2CHFCl
H CH(CH3)CH2SO2CH3 CF3 Ph-4-OCF2CHFBr
H CH(CH3)CH2SO2CH3 CF3 Ph-4-OCF2CF2Br
H CH(CH3)CH2SO2CH3 CF3 Ph-4-OCF2CFCl2
H CH(CH3)CH2SO2CH3 CF3 Ph-4-OCF2CCl3
H CH(CH3)CH2SO2CH3 CF3 Ph-4-OCH2CF2CHF2
H CH(CH3)CH2SO2CH3 CF3 Ph-3-OCF2CHFCF3
H CH(CH3)CH2SO2CH3 CF3 Ph-4-OCF2CHFCF3
H CH(CH3)CH2SO2CH3 CF3 Ph-4-OCH(CF3)2
H CH(CH3)CH2SO2CH3 CF3 Ph-4-OCF2CFBrCF3
H CH(CH3)CH2SO2CH3 CF3 Ph-3-OCF2CHFOCF3
H CH(CH3)CH2SO2CH3 CF3 Ph-4-OCF2CHFOCF3
H CH(CH3)CH2SO2CH3 CF3 Ph-4-OCF2CHFOCF2CF2CF3
H CH(CH3)CH2SO2CH3 CF3 Ph-4-OSO2CH3
H CH(CH3)CH2SO2CH3 CF3 Ph-4-OSO2CF3
H CH(CH3)CH2SO2CH3 CF3 Ph-3-O(Ph-4-Cl)
H CH(CH3)CH2SO2CH3 CF3 Ph-4-O(Ph-4-Cl)
H CH(CH3)CH2SO2CH3 CF3 Ph-4-O(Ph-4-Br)
H CH(CH3)CH2SO2CH3 CF3 Ph-4-O(Ph-4-CF3)
H CH(CH3)CH2SO2CH3 CF3 Ph-4-O(L-45c)Br
H CH(CH3)CH2SO2CH3 CF3 Ph-4-O(L-45c)CF3
H CH(CH3)CH2SO2CH3 CF3 Ph-3-O(L-45e)
H CH(CH3)CH2SO2CH3 CF3 Ph-4-O(L-45e)
H CH(CH3)CH2SO2CH3 CF3 Ph-4-O(L-48b)Br
H CH(CH3)CH2SO2CH3 CF3 Ph-4-SCH3
H CH(CH3)CH2SO2CH3 CF3 Ph-4-SO2CH3
H CH(CH3)CH2SO2CH3 CF3 Ph-3-S(Ph-4-Cl)
H CH(CH3)CH2SO2CH3 CF3 Ph-4-S(Ph-4-Cl)
H CH(CH3)CH2SO2CH3 CF3 Ph-4-S(Ph-4-Br)
H CH(CH3)CH2SO2CH3 CF3 Ph-4-S(Ph-4-CF3)
H CH(CH3)CH2SO2CH3 CF3 Ph-4-S(L-45c)Br
H CH(CH3)CH2SO2CH3 CF3 Ph-4-S(L-45c)CF3
H CH(CH3)CH2SO2CH3 CF3 Ph-4-S(L-45e)
H CH(CH3)CH2SO2CH3 CF3 Ph-4-S(L-48b)Br
H CH(CH3)CH2SO2CH3 CF3 Ph-4-NO2
H CH(CH3)CH2SO2CH3 CF3 Ph-4-CN
H CH(CH3)CH2SO2CH3 CF3 Ph-2,3-F2
H CH(CH3)CH2SO2CH3 CF3 Ph-2,4-F2
H CH(CH3)CH2SO2CH3 CF3 Ph-3,4-F2
H CH(CH3)CH2SO2CH3 CF3 Ph-2,5-F2
H CH(CH3)CH2SO2CH3 CF3 Ph-3,5-F2
H CH(CH3)CH2SO2CH3 CF3 Ph-2-Cl-4-F
H CH(CH3)CH2SO2CH3 CF3 Ph-2-F-3-Cl
H CH(CH3)CH2SO2CH3 CF3 Ph-3-Cl-4-F
H CH(CH3)CH2SO2CH3 CF3 Ph-2-F-4-Cl
H CH(CH3)CH2SO2CH3 CF3 Ph-3-F-4-Cl
H CH(CH3)CH2SO2CH3 CF3 Ph-2,3-Cl2
H CH(CH3)CH2SO2CH3 CF3 Ph-2,4-Cl2
H CH(CH3)CH2SO2CH3 CF3 Ph-2,5-Cl2
H CH(CH3)CH2SO2CH3 CF3 Ph-3,4-Cl2
H CH(CH3)CH2SO2CH3 CF3 Ph-3,5-Cl2
H CH(CH3)CH2SO2CH3 CF3 Ph-3-Br-4-F
H CH(CH3)CH2SO2CH3 CF3 Ph-2-F-4-Br
H CH(CH3)CH2SO2CH3 CF3 Ph-2-F-5-Br
H CH(CH3)CH2SO2CH3 CF3 Ph-3,4-Br2
H CH(CH3)CH2SO2CH3 CF3 Ph-3,5-Br2
H CH(CH3)CH2SO2CH3 CF3 Ph-3-CH3-4-F
H CH(CH3)CH2SO2CH3 CF3 Ph-3-F-4-CH3
H CH(CH3)CH2SO2CH3 CF3 Ph-2-F-5-CH3
H CH(CH3)CH2SO2CH3 CF3 Ph-2,4-(CH3)2
H CH(CH3)CH2SO2CH3 CF3 Ph-3,4-(CH3)2
H CH(CH3)CH2SO2CH3 CF3 Ph-2-F-3-CF3
H CH(CH3)CH2SO2CH3 CF3 Ph-3-CF3-4-F
H CH(CH3)CH2SO2CH3 CF3 Ph-3-CF3-4-Cl
H CH(CH3)CH2SO2CH3 CF3 Ph-2-F-4-CF3
H CH(CH3)CH2SO2CH3 CF3 Ph-3-F-4-CF3
H CH(CH3)CH2SO2CH3 CF3 Ph-2-F-5-CF3
H CH(CH3)CH2SO2CH3 CF3 Ph-3-F-5-CF3
H CH(CH3)CH2SO2CH3 CF3 Ph-2-Cl-4-CF3
H CH(CH3)CH2SO2CH3 CF3 Ph-3,5-(CF3)2
H CH(CH3)CH2SO2CH3 CF3 Ph-3-Br-4-OCH3
H CH(CH3)CH2SO2CH3 CF3 Ph-3-F-4-OCHF2
H CH(CH3)CH2SO2CH3 CF3 Ph-3-Cl-4-OCHF2
H CH(CH3)CH2SO2CH3 CF3 Ph-3-Br-4-OCHF2
H CH(CH3)CH2SO2CH3 CF3 Ph-3-F-4-OCF3
H CH(CH3)CH2SO2CH3 CF3 Ph-3-Cl-4-OCF3
H CH(CH3)CH2SO2CH3 CF3 Ph-3-Br-4-OCF3
H CH(CH3)CH2SO2CH3 CF3 Ph-3-F-4-OCF2Br
H CH(CH3)CH2SO2CH3 CF3 Ph-3-Cl-4-OCF2Br
H CH(CH3)CH2SO2CH3 CF3 Ph-3-Br-4-OCF2Br
H CH(CH3)CH2SO2CH3 CF3 Ph-3-F-4-OCF2CHF2
H CH(CH3)CH2SO2CH3 CF3 Ph-3-Cl-4-OCF2CHF2
H CH(CH3)CH2SO2CH3 CF3 Ph-3-Br-4-OCF2CHF2
H CH(CH3)CH2SO2CH3 CF3 Ph-3-F-4-OCF2CHFCl
H CH(CH3)CH2SO2CH3 CF3 Ph-3-Cl-4-OCF2CHFCl
H CH(CH3)CH2SO2CH3 CF3 Ph-3-Br-4-OCF2CHFCl
H CH(CH3)CH2SO2CH3 CF3 Ph-3-F-4-OCF2CHFCF3
H CH(CH3)CH2SO2CH3 CF3 Ph-3-Cl-4-OCF2CHFCF3
H CH(CH3)CH2SO2CH3 CF3 Ph-3-Br-4-OCF2CHFCF3
H CH(CH3)CH2SO2CH3 CF3 Ph-3-F-4-OCF2CHFOCF3
H CH(CH3)CH2SO2CH3 CF3 Ph-3-Cl-4-OCF2CHFOCF3
H CH(CH3)CH2SO2CH3 CF3 Ph-3-Br-4-OCF2CHFOCF3
H CH(CH3)CH2SO2CH3 CF3 Ph-3-CH3-4-OCF2CHFOCF3
H CH(CH3)CH2SO2CH3 CF3 Ph-3-F-4-OCF2CHFOCF2CF2CF3
H CH(CH3)CH2SO2CH3 CF3 Ph-3-Cl-4-OCF2CHFOCF2CF2CF3
H CH(CH3)CH2SO2CH3 CF3 Ph-3-Br-4-OCF2CHFOCF2CF2CF3
H CH(CH3)CH2SO2CH3 CF3 Ph(-3-OCF2O-4-)
H CH(CH3)CH2SO2CH3 CF3 Ph(-3-OCF2CF2O-4-)
H CH(CH3)CH2SO2CH3 CF3 Ph-3-OPh-4-F
H CH(CH3)CH2SO2CH3 CF3 Ph-3-NO2-4-F
H CH(CH3)CH2SO2CH3 CF3 Ph-3-NO2-4-Cl
H CH(CH3)CH2SO2CH3 CF3 Ph-2-F-5-NO2
H CH(CH3)CH2SO2CH3 CF3 Ph-3-CN-4-F
H CH(CH3)CH2SO2CH3 CF3 Ph-2,3,4-F3
H CH(CH3)CH2SO2CH3 CF3 Ph-2,3,5-F3
H CH(CH3)CH2SO2CH3 CF3 Ph-2,4,5-F3
H CH(CH3)CH2SO2CH3 CF3 Ph-3,4,5-F3
H CH(CH3)CH2SO2CH3 CF3 Ph-2,3-F2-4-CH3
H CH(CH3)CH2SO2CH3 CF3 Ph-2,3-F2-4-CF3
H CH(CH3)CH2SO2CH3 CF3 Ph-3,4-F2-5-CF3
H CH(CH3)CH2SO2CH3 CF3 Ph-2-F-3-Cl-5-CF3
H CH(CH3)CH2SO2CH3 CF3 Ph-3,5-Cl2-4-OCH3
H CH(CH3)CH2SO2CH3 CF3 1-Naph
H CH(CH3)CH2SO2CH3 CF3 2-Naph
H CH(CH3)CH2SO2CH3 CF3 (L-1b)Br
H CH(CH3)CH2SO2CH3 CF3 (L-1c)Cl
H CH(CH3)CH2SO2CH3 CF3 (L-1c)Br
H CH(CH3)CH2SO2CH3 CF3 (L-1c)I
H CH(CH3)CH2SO2CH3 CF3 (L-1c)CF3
H CH(CH3)CH2SO2CH3 CF3 (L-2b)Br
H CH(CH3)CH2SO2CH3 CF3 (L-3b)Cl
H CH(CH3)CH2SO2CH3 CF3 (L-3b)Br
H CH(CH3)CH2SO2CH3 CF3 (L-3c)F
H CH(CH3)CH2SO2CH3 CF3 (L-3c)Cl
H CH(CH3)CH2SO2CH3 CF3 (L-3c)Br
H CH(CH3)CH2SO2CH3 CF3 (L-3c)I
H CH(CH3)CH2SO2CH3 CF3 (L-3c)CF3
H CH(CH3)CH2SO2CH3 CF3 (L-3c)CN
H CH(CH3)CH2SO2CH3 CF3 L-3d
H CH(CH3)CH2SO2CH3 CF3 (L-4b)Cl
H CH(CH3)CH2SO2CH3 CF3 (L-4b)Br
H CH(CH3)CH2SO2CH3 CF3 (L-4b)CN
H CH(CH3)CH2SO2CH3 CF3 (L-10b)Cl
H CH(CH3)CH2SO2CH3 CF3 (L-10b)Br
H CH(CH3)CH2SO2CH3 CF3 (L-15b)CF3
H CH(CH3)CH2SO2CH3 CF3 (L-16a)CHF2
H CH(CH3)CH2SO2CH3 CF3 (L-16a)CF2Br
H CH(CH3)CH2SO2CH3 CF3 (L-17a)Cl
H CH(CH3)CH2SO2CH3 CF3 (L-21b)Cl
H CH(CH3)CH2SO2CH3 CF3 (L-21b)Br
H CH(CH3)CH2SO2CH3 CF3 (L-21b)I
H CH(CH3)CH2SO2CH3 CF3 (L-21b)CF3
H CH(CH3)CH2SO2CH3 CF3 (L-22b)Cl
H CH(CH3)CH2SO2CH3 CF3 (L-22b)Br
H CH(CH3)CH2SO2CH3 CF3 (L-23b)Cl
H CH(CH3)CH2SO2CH3 CF3 (L-23b)Br
H CH(CH3)CH2SO2CH3 CF3 (L-23c)Cl
H CH(CH3)CH2SO2CH3 CF3 (L-23c)Br
H CH(CH3)CH2SO2CH3 CF3 (L-31a)Cl
H CH(CH3)CH2SO2CH3 CF3 (L-31a)Br
H CH(CH3)CH2SO2CH3 CF3 (L-45c)F
H CH(CH3)CH2SO2CH3 CF3 (L-45c)Cl
H CH(CH3)CH2SO2CH3 CF3 (L-45c)Br
H CH(CH3)CH2SO2CH3 CF3 (L-45c)I
H CH(CH3)CH2SO2CH3 CF3 (L-45c)CF3
H CH(CH3)CH2SO2CH3 CF3 L-45e
H CH(CH3)CH2SO2CH3 CF3 L-45f
H CH(CH3)CH2SO2CH3 CF3 (L-46c)F
H CH(CH3)CH2SO2CH3 CF3 (L-46c)Cl
H CH(CH3)CH2SO2CH3 CF3 (L-46c)Br
H CH(CH3)CH2SO2CH3 CF3 (L-46c)I
H CH(CH3)CH2SO2CH3 CF3 (L-46c)CF3
H CH(CH3)CH2SO2CH3 CF3 (L-46c)OCH2CF3
H CH(CH3)CH2SO2CH3 CF3 (L-46c)OCH(CF3)2
H CH(CH3)CH2SO2CH3 CF3 L-46d
H CH(CH3)CH2SO2CH3 CF3 L-47a
H CH(CH3)CH2SO2CH3 CF3 L-47d
H CH(CH3)CH2SO2CH3 CF3 (L-48b)Br
H CH(CH3)CH2SO2CH3 CF3 (L-50b)Cl
H CH(CH3)CH2SO2CH3 CF3 (L-50b)Br
H CH(CH3)CH2SO2CH3 CF3 (L-51b)Cl
H CH(CH3)CH2SO2CH3 CF2Cl Ph-4-Cl
H CH(CH3)CH2SO2CH3 CF2Cl Ph-4-Br
H CH(CH3)CH2SO2CH3 CF2Cl Ph-4-CF3
H CH(CH3)CH2SO2CH3 CF2Cl Ph-4-OCF3
H CH(CH3)CH2SO2CH3 CF2Cl Ph-4-OCF2Br
H CH(CH3)CH2SO2CH3 CF2Cl Ph-4-OCF2CHFCF3
H CH(CH3)CH2SO2CH3 CF2Cl Ph-4-OCF2CHFOCF3
H CH(CH3)CH2SO2CH3 CF2Cl Ph-4-OCF2CHFOCF2CF2CF3
H CH(CH3)CH2SO2CH3 CF2Cl Ph-4-O(L-45g)
H CH(CH3)CH2SO2CH3 CF2Cl Ph-3,4-Cl2
H CH(CH3)CH2SO2CH3 CF2Cl Ph(-3-OCF2O-4-)
H CH(CH3)CH2SO2CH3 CF2Cl Ph(-3-OCF2CF2O-4-)
H CH(CH3)CH2SO2CH3 CF2Cl (L-45c)CF3
H CH(CH3)CH2SO2CH3 CF2Cl L-45f
H CH(CH3)CH2SO2CH3 CF2Cl (L-46c)CF3
H CH(CH3)CH2SO2CH3 CF2Cl L-46d
H CH(CH3)CH2SO2CH3 CFCl2 Ph-4-CF3
H CH(CH3)CH2SO2CH3 CF2Br Ph-4-Cl
H CH(CH3)CH2SO2CH3 CF2Br Ph-4-Br
H CH(CH3)CH2SO2CH3 CF2Br Ph-4-CF3
H CH(CH3)CH2SO2CH3 CF2Br Ph-4-OCF3
H CH(CH3)CH2SO2CH3 CF2Br Ph-4-OCF2Br
H CH(CH3)CH2SO2CH3 CF2Br Ph-4-OCF2CHFCF3
H CH(CH3)CH2SO2CH3 CF2Br Ph-4-OCF2CHFOCF3
H CH(CH3)CH2SO2CH3 CF2Br Ph-4-OCF2CHFOCF2CF2CF3
H CH(CH3)CH2SO2CH3 CF2Br Ph-4-O(L-45g)
H CH(CH3)CH2SO2CH3 CF2Br Ph-3,4-Cl2
H CH(CH3)CH2SO2CH3 CF2Br Ph(-3-OCF2O-4-)
H CH(CH3)CH2SO2CH3 CF2Br Ph(-3-OCF2CF2O-4-)
H CH(CH3)CH2SO2CH3 CF2Br (L-45c)CF3
H CH(CH3)CH2SO2CH3 CF2Br L-45f
H CH(CH3)CH2SO2CH3 CF2Br (L-46c)CF3
H CH(CH3)CH2SO2CH3 CF2Br L-46d
H CH(CH3)CH2SO2CH3 CFClBr Ph-4-OCF3
H CH(CH3)CH2SO2CH3 CFBr2 (L-45c)CF3
H CH(CH3)CH2SO2CH3 CF2CHF2 Ph-4-Br
H CH(CH3)CH2SO2CH3 CF2CF3 Ph-4-Cl
H CH(CH3)CH2SO2CH3 CF2CF3 Ph-4-Br
H CH(CH3)CH2SO2CH3 CF2CF3 Ph-4-CF3
H CH(CH3)CH2SO2CH3 CF2CF3 Ph-4-OCF3
H CH(CH3)CH2SO2CH3 CF2CF3 Ph-4-OCF2Br
H CH(CH3)CH2SO2CH3 CF2CF3 Ph-4-OCF2CHFCF3
H CH(CH3)CH2SO2CH3 CF2CF3 Ph-4-OCF2CHFOCF3
H CH(CH3)CH2SO2CH3 CF2CF3 Ph-4-OCF2CHFOCF2CF2CF3
H CH(CH3)CH2SO2CH3 CF2CF3 Ph-4-O(L-45g)
H CH(CH3)CH2SO2CH3 CF2CF3 Ph-3,4-Cl2
H CH(CH3)CH2SO2CH3 CF2CF3 Ph(-3-OCF2O-4-)
H CH(CH3)CH2SO2CH3 CF2CF3 Ph(-3-OCF2CF2O-4-)
H CH(CH3)CH2SO2CH3 CF2CF3 (L-45c)CF3
H CH(CH3)CH2SO2CH3 CF2CF3 L-45f
H CH(CH3)CH2SO2CH3 CF2CF3 (L-46c)CF3
H CH(CH3)CH2SO2CH3 CF2CF3 L-46d
H CH(CH3)CH2SO2CH3 CF2CF2Cl Ph-4-CF3
H CH(CH3)CH2SO2CH3 CFClCF3 Ph-4-OCF3
H CH(CH3)CH2SO2CH3 CFClCF2Cl (L-45c)CF3
H CH(CH3)CH2SO2CH3 CF2CF2Br Ph-4-Br
H CH(CH3)CH2SO2CH3 CFBrCF3 Ph-4-CF3
H CH(CH3)CH2SO2CH3 CF2CHFCF3 Ph-4-OCF3
H CH(CH3)CH2SO2CH3 CF2CF2CF3 Ph-4-Cl
H CH(CH3)CH2SO2CH3 CF2CF2CF3 Ph-4-Br
H CH(CH3)CH2SO2CH3 CF2CF2CF3 Ph-4-CF3
H CH(CH3)CH2SO2CH3 CF2CF2CF3 Ph-4-OCF3
H CH(CH3)CH2SO2CH3 CF2CF2CF3 Ph-4-OCF2Br
H CH(CH3)CH2SO2CH3 CF2CF2CF3 Ph-4-OCF2CHFCF3
H CH(CH3)CH2SO2CH3 CF2CF2CF3 Ph-4-OCF2CHFOCF3
H CH(CH3)CH2SO2CH3 CF2CF2CF3 Ph-4-OCF2CHFOCF2CF2CF3
H CH(CH3)CH2SO2CH3 CF2CF2CF3 Ph-4-O(L-45g)
H CH(CH3)CH2SO2CH3 CF2CF2CF3 Ph-3,4-Cl2
H CH(CH3)CH2SO2CH3 CF2CF2CF3 Ph(-3-OCF2O-4-)
H CH(CH3)CH2SO2CH3 CF2CF2CF3 Ph(-3-OCF2CF2O-4-)
H CH(CH3)CH2SO2CH3 CF2CF2CF3 (L-45c)CF3
H CH(CH3)CH2SO2CH3 CF2CF2CF3 L-45f
H CH(CH3)CH2SO2CH3 CF2CF2CF3 (L-46c)CF3
H CH(CH3)CH2SO2CH3 CF2CF2CF3 L-46d
H CH(CH3)CH2SO2CH3 CF(CF3)2 (L-45c)CF3
H CH(CH3)CH2SO2CH3 CF2CF2CF2CF3 Ph-4-Br
H CH(CH3)CH2SO2CH3 T-1 Ph-4-CF3
H CH(CH3)CH2SO2CH3 T-2 Ph-4-OCF3
H CH(CH3)CH2SO2CH3 CH2OCH3 (L-45c)CF3
H CH(CH3)CH2SO2CH3 CH2OEt Ph-4-Br
H CH(CH3)CH2SO2CH3 CH2OCH2CF3 Ph-4-CF3
H CH(CH3)CH2SO2CH3 CH2OCH(CF3)2 Ph-4-OCF3
H CH(CH3)CH2SO2CH3 CF2OCH3 Ph-4-Cl
H CH(CH3)CH2SO2CH3 CF2OCH3 Ph-4-Br
H CH(CH3)CH2SO2CH3 CF2OCH3 Ph-4-CF3
H CH(CH3)CH2SO2CH3 CF2OCH3 Ph-4-OCF3
H CH(CH3)CH2SO2CH3 CF2OCH3 Ph-4-OCF2Br
H CH(CH3)CH2SO2CH3 CF2OCH3 Ph-4-OCF2CHFCF3
H CH(CH3)CH2SO2CH3 CF2OCH3 Ph-4-OCF2CHFOCF3
H CH(CH3)CH2SO2CH3 CF2OCH3 Ph-4-OCF2CHFOCF2CF2CF3
H CH(CH3)CH2SO2CH3 CF2OCH3 Ph-4-O(L-45g)
H CH(CH3)CH2SO2CH3 CF2OCH3 Ph-3,4-Cl2
H CH(CH3)CH2SO2CH3 CF2OCH3 Ph(-3-OCF2O-4-)
H CH(CH3)CH2SO2CH3 CF2OCH3 Ph(-3-OCF2CF2O-4-)
H CH(CH3)CH2SO2CH3 CF2OCH3 (L-45c)CF3
H CH(CH3)CH2SO2CH3 CF2OCH3 L-45f
H CH(CH3)CH2SO2CH3 CF2OCH3 (L-46c)CF3
H CH(CH3)CH2SO2CH3 CF2OCH3 L-46d
H CH(CH3)CH2SO2CH3 CH2SCH3 (L-45c)CF3
H CH(CH3)CH2SO2CH3 CH2SO2CH3 Ph-4-Br
H CH(CH3)CH2SO2CH3 CH2SCF3 Ph-4-CF3
H CH(CH3)CH2SO2CH3 CF2SCH3 Ph-4-Cl
H CH(CH3)CH2SO2CH3 CF2SCH3 Ph-4-Br
H CH(CH3)CH2SO2CH3 CF2SCH3 Ph-4-CF3
H CH(CH3)CH2SO2CH3 CF2SCH3 Ph-4-OCF3
H CH(CH3)CH2SO2CH3 CF2SCH3 Ph-4-OCF2Br
H CH(CH3)CH2SO2CH3 CF2SCH3 Ph-4-OCF2CHFCF3
H CH(CH3)CH2SO2CH3 CF2SCH3 Ph-4-OCF2CHFOCF3
H CH(CH3)CH2SO2CH3 CF2SCH3 Ph-4-OCF2CHFOCF2CF2CF3
H CH(CH3)CH2SO2CH3 CF2SCH3 Ph-4-O(L-45g)
H CH(CH3)CH2SO2CH3 CF2SCH3 Ph-3,4-Cl2
H CH(CH3)CH2SO2CH3 CF2SCH3 Ph(-3-OCF2O-4-)
H CH(CH3)CH2SO2CH3 CF2SCH3 Ph(-3-OCF2CF2O-4-)
H CH(CH3)CH2SO2CH3 CF2SCH3 (L-45c)CF3
H CH(CH3)CH2SO2CH3 CF2SCH3 L-45f
H CH(CH3)CH2SO2CH3 CF2SCH3 (L-46c)CF3
H CH(CH3)CH2SO2CH3 CF2SCH3 L-46d
H CH(CH3)CH2SO2CH3 CF2SEt Ph-4-OCF3
H CH(CH3)CH2SO2CH3 CF2SPr-n (L-45c)CF3
H CH(CH3)CH2SO2CH3 CF2SPr-i Ph-4-Br
H CH(CH3)CH2SO2CH3 CF2SCH2Ph Ph-4-CF3
H CH(CH3)CH2SO2CH3 CF2SPh Ph-4-OCF3
H CH(CH3)CH2SO2CH3 CF2C(O)OEt (L-45c)CF3
H CH(CH3)CH2SO2CH3 CF2SO2N(CH3)2 Ph-4-Br
H CH(CH3)CH2SO2CH3 C(O)OEt Ph-4-CF3
H CH(CH3)CH2SO2CH3 C(O)SEt Ph-4-OCF3
H CH(CH3)CH2SEt CF3 CH=CH(Ph-4-Cl)
H CH(CH3)CH2SEt CF3 Ph-4-Cl
H CH(CH3)CH2SEt CF3 Ph-4-Br
H CH(CH3)CH2SEt CF3 Ph-4-CF3
H CH(CH3)CH2SEt CF3 Ph-4-OCF3
H CH(CH3)CH2SEt(R) CF3 Ph-4-OCF3
H CH(CH3)CH2SEt(S) CF3 Ph-4-OCF3
H CH(CH3)CH2SEt CF3 Ph-4-OCF2Br
H CH(CH3)CH2SEt CF3 Ph-4-OCF2CHFCF3
H CH(CH3)CH2SEt CF3 Ph-4-OCF2CHFOCF3
H CH(CH3)CH2SEt CF3 Ph-4-OCF2CHFOCF2CF2CF3
H CH(CH3)CH2SEt CF3 Ph-4-O(L-45g)
H CH(CH3)CH2SEt CF3 Ph-3,4-Cl2
H CH(CH3)CH2SEt CF3 Ph(-3-OCF2O-4-)
H CH(CH3)CH2SEt CF3 Ph(-3-OCF2CF2O-4-)
H CH(CH3)CH2SEt CF3 (L-45c)CF3
H CH(CH3)CH2SEt CF3 L-45f
H CH(CH3)CH2SEt CF3 (L-46c)CF3
H CH(CH3)CH2SEt CF3 L-46d
H CH(CH3)CH2S(O)Et CF3 CH=CH(Ph-4-Cl)
H CH(CH3)CH2S(O)Et CF3 Ph-4-Cl
H CH(CH3)CH2S(O)Et CF3 Ph-4-Br
H CH(CH3)CH2S(O)Et CF3 Ph-4-CF3
H CH(CH3)CH2S(O)Et CF3 Ph-4-OCF3
H CH(CH3)CH2S(O)Et CF3 Ph-4-OCF2Br
H CH(CH3)CH2S(O)Et CF3 Ph-4-OCF2CHFCF3
H CH(CH3)CH2S(O)Et CF3 Ph-4-OCF2CHFOCF3
H CH(CH3)CH2S(O)Et CF3 Ph-4-OCF2CHFOCF2CF2CF3
H CH(CH3)CH2S(O)Et CF3 Ph-4-O(L-45g)
H CH(CH3)CH2S(O)Et CF3 Ph-3,4-Cl2
H CH(CH3)CH2S(O)Et CF3 Ph(-3-OCF2O-4-)
H CH(CH3)CH2S(O)Et CF3 Ph(-3-OCF2CF2O-4-)
H CH(CH3)CH2S(O)Et CF3 (L-45c)CF3
H CH(CH3)CH2S(O)Et CF3 L-45f
H CH(CH3)CH2S(O)Et CF3 (L-46c)CF3
H CH(CH3)CH2S(O)Et CF3 L-46d
H CH(CH3)CH2SO2Et CF3 CH=CH(Ph-4-Cl)
H CH(CH3)CH2SO2Et CF3 Ph-4-Cl
H CH(CH3)CH2SO2Et CF3 Ph-4-Br
H CH(CH3)CH2SO2Et CF3 Ph-4-CF3
H CH(CH3)CH2SO2Et CF3 Ph-4-OCF3
H CH(CH3)CH2SO2Et CF3 Ph-4-OCF2Br
H CH(CH3)CH2SO2Et CF3 Ph-4-OCF2CHFCF3
H CH(CH3)CH2SO2Et CF3 Ph-4-OCF2CHFOCF3
H CH(CH3)CH2SO2Et CF3 Ph-4-OCF2CHFOCF2CF2CF3
H CH(CH3)CH2SO2Et CF3 Ph-4-O(L-45g)
H CH(CH3)CH2SO2Et CF3 Ph-3,4-Cl2
H CH(CH3)CH2SO2Et CF3 Ph(-3-OCF2O-4-)
H CH(CH3)CH2SO2Et CF3 Ph(-3-OCF2CF2O-4-)
H CH(CH3)CH2SO2Et CF3 (L-45c)CF3
H CH(CH3)CH2SO2Et CF3 L-45f
H CH(CH3)CH2SO2Et CF3 (L-46c)CF3
H CH(CH3)CH2SO2Et CF3 L-46d
H CH(CH3)CH2SPr-n CF3 Ph-4-Br
H CH(CH3)CH2SPr-n CF3 Ph-4-CF3
H CH(CH3)CH2SPr-n CF3 Ph-4-OCF3
H CH(CH3)CH2SPr-n CF3 (L-45c)CF3
H CH(CH3)CH2SPr-i CF3 (L-45c)CF3
H CH(CH3)CH2SO2Pr-i CF3 Ph-4-Br
H CH(CH3)CH2SBu-n CF3 Ph-4-CF3
H CH(CH3)CH2SBu-i CF3 Ph-4-Br
H CH(CH3)CH2SBu-i CF3 Ph-4-CF3
H CH(CH3)CH2SBu-i CF3 Ph-4-OCF3
H CH(CH3)CH2SBu-i CF3 (L-45c)CF3
H CH(CH3)CH2SBu-t CF3 Ph-4-Br
H CH(CH3)CH2SBu-t CF3 Ph-4-CF3
H CH(CH3)CH2SBu-t CF3 Ph-4-OCF3
H CH(CH3)CH2SBu-t CF3 (L-45c)CF3
H CH(CH3)CH2SO2Bu-t CF3 Ph-4-OCF3
H CH(CH3)CH2SHex-n CF3 (L-45c)CF3
H CH(CH3)CH2SHex-c CF3 Ph-4-Br
H CH(CH3)CH2SCH2CF3 CF3 Ph-4-CF3
H CH(CH3)CH2S(O)CH2CF3 CF3 Ph-4-OCF3
H CH(CH3)CH2SO2CH2CF3 CF3 (L-45c)CF3
H CH(CH3)CH2SCH2CH2OH CF3 Ph-4-Br
H CH(CH3)CH2SCH2CH2OCH3 CF3 Ph-4-CF3
H CH(CH3)CH2S(O)CH2CH2OCH3 CF3 Ph-4-OCF3
H CH(CH3)CH2SO2CH2CH2OCH3 CF3 (L-45c)CF3
H CH(CH3)CH2SCH2CH2OEt CF3 Ph-4-Br
H CH(CH3)CH2S(O)CH2CH2OEt CF3 Ph-4-CF3
H CH(CH3)CH2SO2CH2CH2OEt CF3 Ph-4-OCF3
H CH(CH3)CH2SCH2CH2OC(O)CF3 CF3 (L-45c)CF3
H CH(CH3)CH2SCH2CH2SCH3 CF3 Ph-4-Br
H CH(CH3)CH2SCH2Si(CH3)3 CF3 Ph-4-Br
H CH(CH3)CH2SCH2Si(CH3)3 CF3 Ph-4-CF3
H CH(CH3)CH2SCH2Si(CH3)3 CF3 Ph-4-OCF3
H CH(CH3)CH2SCH2Si(CH3)3 CF3 (L-45c)CF3
H CH(CH3)CH2SCH2C(O)CH3 CF3 Ph-4-CF3
H CH(CH3)CH2SCH2CH2C(O)OCH3 CF3 Ph-4-OCF3
H CH(CH3)CH2S(O)CH2CH2C(O)OCH3 CF3 (L-45c)CF3
H CH(CH3)CH2SO2CH2CH2C(O)OCH3 CF3 Ph-4-Br
H CH(CH3)CH2SCH2C(O)N(Et)2 CF3 Ph-4-CF3
H CH(CH3)CH2S(O)CH2C(O)N(Et)2 CF3 Ph-4-OCF3
H CH(CH3)CH2SO2CH2C(O)N(Et)2 CF3 (L-45c)CF3
H CH(CH3)CH2SCH2(Ph-2,4-Cl2) CF3 Ph-4-Br
H CH(CH3)CH2SCH2CH=CH2 CF3 Ph-4-CF3
H CH(CH3)CH2SCH2C≡CH CF3 Ph-4-OCF3
H CH(CH3)CH2SC(O)CH3 CF3 (L-45c)CF3
H CH(CH3)CH2SSCH3 CF3 CH=CH(Ph-4-Cl)
H CH(CH3)CH2SSCH3 CF3 Ph-4-Cl
H CH(CH3)CH2SSCH3 CF3 Ph-4-Br
H CH(CH3)CH2SSCH3 CF3 Ph-4-CF3
H CH(CH3)CH2SSCH3 CF3 Ph-4-OCF3
H CH(CH3)CH2SSCH3 CF3 Ph-4-OCF2Br
H CH(CH3)CH2SSCH3 CF3 Ph-4-OCF2CHFCF3
H CH(CH3)CH2SSCH3 CF3 Ph-4-OCF2CHFOCF3
H CH(CH3)CH2SSCH3 CF3 Ph-4-OCF2CHFOCF2CF2CF3
H CH(CH3)CH2SSCH3 CF3 Ph-4-O(L-45g)
H CH(CH3)CH2SSCH3 CF3 Ph-3,4-Cl2
H CH(CH3)CH2SSCH3 CF3 Ph(-3-OCF2O-4-)
H CH(CH3)CH2SSCH3 CF3 Ph(-3-OCF2CF2O-4-)
H CH(CH3)CH2SSCH3 CF3 (L-45c)CF3
H CH(CH3)CH2SSCH3 CF3 L-45f
H CH(CH3)CH2SSCH3 CF3 (L-46c)CF3
H CH(CH3)CH2SSCH3 CF3 L-46d
H CH(CH3)CH2SS(Ph-2-NO2) CF3 Ph-4-Br
H CH(CH3)CH2SO2NH2 CF3 Ph-4-CF3
H CH(CH3)CH2SO2NHCH3 CF3 Ph-4-Br
H CH(CH3)CH2SO2NHCH3 CF3 Ph-4-CF3
H CH(CH3)CH2SO2NHCH3 CF3 Ph-4-OCF3
H CH(CH3)CH2SO2NHCH3 CF3 (L-45c)CF3
H CH(CH3)CH2SO2NHEt CF3 CF2O(Ph-4-Cl)
H CH(CH3)CH2SO2NHEt CF3 CH=CH(Ph-4-Cl)
H CH(CH3)CH2SO2NHEt CF3 CH=CH(Ph-4-Br)
H CH(CH3)CH2SO2NHEt CF3 CH=CH(Ph-4-CF3)
H CH(CH3)CH2SO2NHEt CF3 CH=CH(Ph-4-OCF3)
H CH(CH3)CH2SO2NHEt CF3 CH=CH(Ph-3,4-Cl2)
H CH(CH3)CH2SO2NHEt CF3 Ph-4-F
H CH(CH3)CH2SO2NHEt CF3 Ph-4-Cl
H CH(CH3)CH2SO2NHEt CF3 Ph-4-Br
H CH(CH3)CH2SO2NHEt CF3 Ph-4-CF3
H CH(CH3)CH2SO2NHEt CF3 Ph-4-OCF3
H CH(CH3)CH2SO2NHEt(S) CF3 Ph-4-OCF3
H CH(CH3)CH2SO2NHEt CF3 Ph-4-OCF2Br
H CH(CH3)CH2SO2NHEt CF3 Ph-4-OCF2CHF2
H CH(CH3)CH2SO2NHEt CF3 Ph-4-OCF2CHFCF3
H CH(CH3)CH2SO2NHEt CF3 Ph-4-OCF2CHFOCF3
H CH(CH3)CH2SO2NHEt CF3 Ph-4-OCF2CHFOCF2CF2CF3
H CH(CH3)CH2SO2NHEt CF3 Ph-4-O(L-45g)
H CH(CH3)CH2SO2NHEt CF3 Ph-3,4-F2
H CH(CH3)CH2SO2NHEt CF3 Ph-3-F-4-Cl
H CH(CH3)CH2SO2NHEt CF3 Ph-3,4-Cl2
H CH(CH3)CH2SO2NHEt CF3 Ph(-3-OCF2O-4-)
H CH(CH3)CH2SO2NHEt CF3 Ph(-3-OCF2CF2O-4-)
H CH(CH3)CH2SO2NHEt CF3 (L-45c)CF3
H CH(CH3)CH2SO2NHEt CF3 L-45f
H CH(CH3)CH2SO2NHEt CF3 (L-46c)CF3
H CH(CH3)CH2SO2NHEt CF3 L-46d
H CH(CH3)CH2SO2NHPr-n CF3 Ph-4-OCF3
H CH(CH3)CH2SO2NHPr-i CF3 (L-45c)CF3
H CH(CH3)CH2SO2NHBu-n CF3 Ph-4-Br
H CH(CH3)CH2SO2NHBu-t CF3 Ph-4-CF3
H CH(CH3)CH2SO2NHCH2CH2Cl CF3 Ph-4-OCF3
H CH(CH3)CH2SO2NHCH2CH2OH CF3 (L-45c)CF3
H CH(CH3)CH2SO2NHCH2CH2OCH3 CF3 Ph-4-Br
H CH(CH3)CH2SO2NHCH2CH2SCH3 CF3 Ph-4-CF3
H CH(CH3)CH2SO2NHCH2CH2S(O)CH3 CF3 Ph-4-OCF3
H CH(CH3)CH2SO2NHCH2CH2SO2CH3 CF3 (L-45c)CF3
H CH(CH3)CH2SO2NHCH(CH3)CH2SCH3 CF3 Ph-4-Br
H CH(CH3)CH2SO2NHCH(CH3)CH2SCH3(S,S) CF3 Ph-4-CF3
H CH(CH3)CH2SO2NHCH(CH3)CH2S(O)CH3 CF3 Ph-4-OCF3
H CH(CH3)CH2SO2NHCH(CH3)CH2S(O)CH3(S,S) CF3 (L-45c)CF3
H CH(CH3)CH2SO2NHCH(CH3)CH2SO2CH3 CF3 Ph-4-Br
H CH(CH3)CH2SO2NHCH(CH3)CH2SO2CH3(S,S) CF3 Ph-4-CF3
H CH(CH3)CH2SO2NHC(CH3)2CH2SCH3 CF3 Ph-4-OCF3
H CH(CH3)CH2SO2NHCH(CH3)C(O)NH2 CF3 (L-45c)CF3
H CH(CH3)CH2SO2NHCH(CH3)C(O)NHCH3 CF3 Ph-4-Br
H CH(CH3)CH2SO2NHCH(CH3)C(O)NHEt CF3 Ph-4-CF3
H CH(CH3)CH2SO2NHCH2CH=CH2 CF3 Ph-4-OCF3
H CH(CH3)CH2SO2NHCH2C≡CH CF3 (L-45c)CF3
H CH(CH3)CH2SO2NHCH2Ph CF3 Ph-4-Br
H CH(CH3)CH2SO2NHCH2Ph(S) CF3 Ph-4-CF3
H CH(CH3)CH2SO2NHCH2(Ph-2-F) CF3 Ph-4-OCF3
H CH(CH3)CH2SO2NHCH2(Ph-2-Cl) CF3 (L-45c)CF3
H CH(CH3)CH2SO2NHCH2(Ph-2-Br) CF3 Ph-4-Br
H CH(CH3)CH2SO2NHCH2(Ph-2-OCH3) CF3 Ph-4-CF3
H CH(CH3)CH2SO2NHCH2(Ph-3-OCH3) CF3 Ph-4-OCF3
H CH(CH3)CH2SO2NHCH2(Ph-4-OCH3) CF3 (L-45c)CF3
H CH(CH3)CH2SO2NHCH2(Ph-4-SCF3) CF3 Ph-4-Br
H CH(CH3)CH2SO2NHCH2(Ph-2-NO2) CF3 Ph-4-CF3
H CH(CH3)CH2SO2NHCH2(Ph-3-NO2) CF3 Ph-4-OCF3
H CH(CH3)CH2SO2NHCH2(Ph-4-NO2) CF3 (L-45c)CF3
H CH(CH3)CH2SO2NHCH2(Ph-3-CN) CF3 Ph-4-Br
H CH(CH3)CH2SO2NHCH2(Ph-4-CN) CF3 Ph-4-CF3
H CH(CH3)CH2SO2NHCH2(L-45a) CF3 Ph-4-OCF3
H CH(CH3)CH2SO2NHCH2(L-46a) CF3 (L-45c)CF3
H CH(CH3)CH2SO2NHCH2(L-47a) CF3 Ph-4-Br
H CH(CH3)CH2SO2NHCH(CH3)Ph CF3 Ph-4-CF3
H CH(CH3)CH2SO2NHCH(CH3)Ph(R) CF3 Ph-4-OCF3
H CH(CH3)CH2SO2NHCH(CH3)Ph(S) CF3 (L-45c)CF3
H CH(CH3)CH2SO2NHCH2CH2Ph CF3 Ph-4-Br
H CH(CH3)CH2SO2NH(Ph-2-OCH3) CF3 Ph-4-CF3
H CH(CH3)CH2SO2N(CH3)2 CF3 Ph-4-Br
H CH(CH3)CH2SO2N(CH3)2 CF3 Ph-4-CF3
H CH(CH3)CH2SO2N(CH3)2 CF3 Ph-4-OCF3
H CH(CH3)CH2SO2N(CH3)2 CF3 (L-45c)CF3
H CH(CH3)CH2SO2N(CH3)Et CF3 Ph-4-OCF3
H CH(CH3)CH2SO2N(Et)2 CF3 CF2O(Ph-4-Cl)
H CH(CH3)CH2SO2N(Et)2 CF3 CH=CH(Ph-4-Cl)
H CH(CH3)CH2SO2N(Et)2 CF3 CH=CH(Ph-4-Br)
H CH(CH3)CH2SO2N(Et)2 CF3 CH=CH(Ph-4-CF3)
H CH(CH3)CH2SO2N(Et)2 CF3 CH=CH(Ph-4-OCF3)
H CH(CH3)CH2SO2N(Et)2 CF3 CH=CH(Ph-3,4-Cl2)
H CH(CH3)CH2SO2N(Et)2 CF3 Ph-4-F
H CH(CH3)CH2SO2N(Et)2 CF3 Ph-4-Cl
H CH(CH3)CH2SO2N(Et)2 CF3 Ph-4-Br
H CH(CH3)CH2SO2N(Et)2 CF3 Ph-4-CF3
H CH(CH3)CH2SO2N(Et)2 CF3 Ph-4-OCF3
H CH(CH3)CH2SO2N(Et)2(S) CF3 Ph-4-OCF3
H CH(CH3)CH2SO2N(Et)2 CF3 Ph-4-OCF2Br
H CH(CH3)CH2SO2N(Et)2 CF3 Ph-4-OCF2CHF2
H CH(CH3)CH2SO2N(Et)2 CF3 Ph-4-OCF2CHFCF3
H CH(CH3)CH2SO2N(Et)2 CF3 Ph-4-OCF2CHFOCF3
H CH(CH3)CH2SO2N(Et)2 CF3 Ph-4-OCF2CHFOCF2CF2CF3
H CH(CH3)CH2SO2N(Et)2 CF3 Ph-4-O(L-45g)
H CH(CH3)CH2SO2N(Et)2 CF3 Ph-3,4-F2
H CH(CH3)CH2SO2N(Et)2 CF3 Ph-3-F-4-Cl
H CH(CH3)CH2SO2N(Et)2 CF3 Ph-3,4-Cl2
H CH(CH3)CH2SO2N(Et)2 CF3 Ph(-3-OCF2O-4-)
H CH(CH3)CH2SO2N(Et)2 CF3 Ph(-3-OCF2CF2O-4-)
H CH(CH3)CH2SO2N(Et)2 CF3 (L-45c)CF3
H CH(CH3)CH2SO2N(Et)2 CF3 L-45f
H CH(CH3)CH2SO2N(Et)2 CF3 (L-46c)CF3
H CH(CH3)CH2SO2N(Et)2 CF3 L-46d
H CH(CH3)CH2SO2(T-19) CF3 (L-45c)CF3
H CH(CH3)CH2SO2(T-20) CF3 Ph-4-Br
H CH(CH3)CH2SO2(T-21) CF3 Ph-4-CF3
H CH(CH3)CH2SO2N(CH3)CH2Ph CF3 Ph-4-OCF3
H CH(CH3)CH2SO2N(Et)CH2Ph CF3 (L-45c)CF3
H CH(CH3)CH2SC(O)NHEt CF3 Ph-4-Br
H CH(CH3)CH2SC(O)N(CH3)2 CF3 Ph-4-CF3
H CH(CH3)CH2SC(O)N(Et)2 CF3 Ph-4-OCF3
H CH(CH3)CH2SC(S)NHCH3 CF3 (L-45c)CF3
H CH(CH3)CH2SC(S)NHEt CF3 Ph-4-Br
H CH(CH3)CH2SC(S)N(CH3)2 CF3 Ph-4-CF3
H CH(CH3)CH2SPh CF3 Ph-4-Br
H CH(CH3)CH2SPh CF3 Ph-4-CF3
H CH(CH3)CH2SPh CF3 Ph-4-OCF3
H CH(CH3)CH2SPh CF3 (L-45c)CF3
H CH(CH3)CH2S(L-21a) CF3 Ph-4-OCF3
H CH(CH3)CH2SO2(L-21a) CF3 (L-45c)CF3
H CH(CH3)CH2S(L-45a) CF3 Ph-4-Br
H CH(CH3)CH2S(L-45a) CF3 Ph-4-CF3
H CH(CH3)CH2S(L-45a) CF3 Ph-4-OCF3
H CH(CH3)CH2S(L-45a) CF3 (L-45c)CF3
H CH(CH3)CH2S(O)(L-45a) CF3 Ph-4-Br
H CH(CH3)CH2S(O)(L-45a) CF3 Ph-4-CF3
H CH(CH3)CH2S(O)(L-45a) CF3 Ph-4-OCF3
H CH(CH3)CH2S(O)(L-45a) CF3 (L-45c)CF3
H CH(CH3)CH2SO2(L-45a) CF3 Ph-4-Br
H CH(CH3)CH2SO2(L-45a) CF3 Ph-4-CF3
H CH(CH3)CH2SO2(L-45a) CF3 Ph-4-OCF3
H CH(CH3)CH2SO2(L-45a) CF3 (L-45c)CF3
H CH(CH3)CH2S(L-48a) CF3 Ph-4-Br
H CH(CH3)CH2S(O)(L-48a) CF3 Ph-4-CF3
H CH(CH3)CH2SO2(L-48a) CF3 Ph-4-OCF3
H CH(CH3)CH2S(L-48b) CF3 (L-45c)CF3
H CH(CH3)CH2S(O)(L-48b) CF3 Ph-4-Br
H CH(CH3)CH2SO2(L-48b) CF3 Ph-4-CF3
H CH(Et)CH2SCH3 CF3 (L-45c)CF3
H CH(CH2SCH3)2 CF3 Ph-4-Br
H CH(Ph)CH2SCH3 CF3 Ph-4-CF3
H CH(Ph)CH2S(O)CH3 CF3 Ph-4-OCF3
H CH(Ph)CH2SO2CH3 CF3 (L-45c)CF3
H CH(CH3)CH(CH3)SCH3 CF3 Ph-4-Br
H CH(CH3)CH(CH3)SO2CH3 CF3 Ph-4-CF3
H CH(CH3)CH(CH3)SEt CF3 Ph-4-OCF3
H CH(CH3)CH(CH3)SO2Et CF3 (L-45c)CF3
H C(CH3)2CH2SCH3 CH3 CF2O(Ph-4-Cl)
H C(CH3)2CH2SCH3 CH3 CH=CH(Ph-4-Cl)
H C(CH3)2CH2SCH3 CH3 CH=CH(Ph-4-OCF3)
H C(CH3)2CH2SCH3 CH3 CH=CH(Ph-3,4-Cl2)
H C(CH3)2CH2SCH3 CH3 Ph-4-F
H C(CH3)2CH2SCH3 CH3 Ph-4-Cl
H C(CH3)2CH2SCH3 CH3 Ph-4-Br
H C(CH3)2CH2SCH3 CH3 Ph-4-I
H C(CH3)2CH2SCH3 CH3 Ph-4-CF3
H C(CH3)2CH2SCH3 CH3 Ph-4-OCHF2
H C(CH3)2CH2SCH3 CH3 Ph-4-OCF3
H C(CH3)2CH2SCH3 CH3 Ph-4-OCF2Br
H C(CH3)2CH2SCH3 CH3 Ph-4-OCF2CHF2
H C(CH3)2CH2SCH3 CH3 Ph-4-OCF2CHFCl
H C(CH3)2CH2SCH3 CH3 Ph-4-OCF2CHFCF3
H C(CH3)2CH2SCH3 CH3 Ph-4-OCF2CHFOCF3
H C(CH3)2CH2SCH3 CH3 Ph-4-OCF2CHFOCF2CF2CF3
H C(CH3)2CH2SCH3 CH3 Ph-4-O(L-45g)
H C(CH3)2CH2SCH3 CH3 Ph-3,4-Cl2
H C(CH3)2CH2SCH3 CH3 Ph(-3-OCF2O-4-)
H C(CH3)2CH2SCH3 CH3 Ph(-3-OCF2CF2O-4-)
H C(CH3)2CH2SCH3 CH3 (L-45c)Cl
H C(CH3)2CH2SCH3 CH3 (L-45c)Br
H C(CH3)2CH2SCH3 CH3 (L-45c)CF3
H C(CH3)2CH2SCH3 CH3 L-45e
H C(CH3)2CH2SCH3 CH3 L-45f
H C(CH3)2CH2SCH3 CH3 (L-46c)Cl
H C(CH3)2CH2SCH3 CH3 (L-46c)Br
H C(CH3)2CH2SCH3 CH3 (L-46c)CF3
H C(CH3)2CH2SCH3 CH3 L-46d
H C(CH3)2CH2SCH3 Et Ph-4-Cl
H C(CH3)2CH2SCH3 Et Ph-4-Br
H C(CH3)2CH2SCH3 Et Ph-4-CF3
H C(CH3)2CH2SCH3 Et Ph-4-OCF3
H C(CH3)2CH2SCH3 Et Ph-4-OCF2Br
H C(CH3)2CH2SCH3 Et Ph-4-OCF2CHFCF3
H C(CH3)2CH2SCH3 Et Ph-4-OCF2CHFOCF3
H C(CH3)2CH2SCH3 Et Ph-4-OCF2CHFOCF2CF2CF3
H C(CH3)2CH2SCH3 Et Ph-4-O(L-45g)
H C(CH3)2CH2SCH3 Et Ph-3,4-Cl2
H C(CH3)2CH2SCH3 Et Ph(-3-OCF2O-4-)
H C(CH3)2CH2SCH3 Et Ph(-3-OCF2CF2O-4-)
H C(CH3)2CH2SCH3 Et (L-45c)CF3
H C(CH3)2CH2SCH3 n-Pr Ph-4-Br
H C(CH3)2CH2SCH3 n-Pr Ph-4-CF3
H C(CH3)2CH2SCH3 n-Pr Ph-4-OCF3
H C(CH3)2CH2SCH3 n-Pr (L-45c)CF3
H C(CH3)2CH2SCH3 i-Pr Ph-4-Br
H C(CH3)2CH2SCH3 i-Pr Ph-4-CF3
H C(CH3)2CH2SCH3 i-Pr Ph-4-OCF3
H C(CH3)2CH2SCH3 i-Pr (L-45c)CF3
H C(CH3)2CH2SCH3 c-Pr Ph-4-Br
H C(CH3)2CH2SCH3 c-Pr Ph-4-CF3
H C(CH3)2CH2SCH3 c-Pr Ph-4-OCF3
H C(CH3)2CH2SCH3 c-Pr (L-45c)CF3
H C(CH3)2CH2SCH3 n-Bu Ph-4-Br
H C(CH3)2CH2SCH3 CH2F Ph-4-CF3
H C(CH3)2CH2SCH3 CH2Cl Ph-4-OCF3
H C(CH3)2CH2SCH3 CH2Br (L-45c)CF3
H C(CH3)2CH2SCH3 CHF2 Ph-4-Cl
H C(CH3)2CH2SCH3 CHF2 Ph-4-Br
H C(CH3)2CH2SCH3 CHF2 Ph-4-CF3
H C(CH3)2CH2SCH3 CHF2 Ph-4-OCF3
H C(CH3)2CH2SCH3 CHF2 Ph-4-OCF2Br
H C(CH3)2CH2SCH3 CHF2 Ph-4-OCF2CHFCF3
H C(CH3)2CH2SCH3 CHF2 Ph-4-OCF2CHFOCF3
H C(CH3)2CH2SCH3 CHF2 Ph-4-OCF2CHFOCF2CF2CF3
H C(CH3)2CH2SCH3 CHF2 Ph-4-O(L-45g)
H C(CH3)2CH2SCH3 CHF2 Ph-3,4-Cl2
H C(CH3)2CH2SCH3 CHF2 Ph(-3-OCF2O-4-)
H C(CH3)2CH2SCH3 CHF2 Ph(-3-OCF2CF2O-4-)
H C(CH3)2CH2SCH3 CHF2 (L-45c)CF3
H C(CH3)2CH2SCH3 CHF2 L-45f
H C(CH3)2CH2SCH3 CHF2 (L-46c)CF3
H C(CH3)2CH2SCH3 CHF2 L-46d
H C(CH3)2CH2SCH3 CHFCl Ph-4-Br
H C(CH3)2CH2SCH3 CHFBr Ph-4-CF3
H C(CH3)2CH2SCH3 CF3 c-Pr
H C(CH3)2CH2SCH3 CF3 c-Bu
H C(CH3)2CH2SCH3 CF3 c-Pen
H C(CH3)2CH2SCH3 CF3 c-Hex
H C(CH3)2CH2SCH3 CF3 T-1
H C(CH3)2CH2SCH3 CF3 T-2
H C(CH3)2CH2SCH3 CF3 T-3
H C(CH3)2CH2SCH3 CF3 T-4
H C(CH3)2CH2SCH3 CF3 T-5
H C(CH3)2CH2SCH3 CF3 CH2OCH3
H C(CH3)2CH2SCH3 CF3 CH2OEt
H C(CH3)2CH2SCH3 CF3 CH2OPr-n
H C(CH3)2CH2SCH3 CF3 CH2OPr-i
H C(CH3)2CH2SCH3 CF3 CH2OBu-n
H C(CH3)2CH2SCH3 CF3 CH2OC(O)(Ph-2-Cl)
H C(CH3)2CH2SCH3 CF3 CH2OC(O)(Ph-3-Cl)
H C(CH3)2CH2SCH3 CF3 CH2OC(O)(Ph-4-Cl)
H C(CH3)2CH2SCH3 CF3 CH2OPh
H C(CH3)2CH2SCH3 CF3 CH2O(Ph-2-F)
H C(CH3)2CH2SCH3 CF3 CH2O(Ph-3-F)
H C(CH3)2CH2SCH3 CF3 CH2O(Ph-4-F)
H C(CH3)2CH2SCH3 CF3 CH2O(Ph-2-Cl)
H C(CH3)2CH2SCH3 CF3 CH2O(Ph-3-Cl)
H C(CH3)2CH2SCH3 CF3 CH2O(Ph-4-Cl)
H C(CH3)2CH2SCH3 CF3 CH2O(Ph-2-Br)
H C(CH3)2CH2SCH3 CF3 CH2O(Ph-3-Br)
H C(CH3)2CH2SCH3 CF3 CH2O(Ph-4-Br)
H C(CH3)2CH2SCH3 CF3 CH2O(Ph-2-CF3)
H C(CH3)2CH2SCH3 CF3 CH2O(Ph-3-CF3)
H C(CH3)2CH2SCH3 CF3 CH2O(Ph-4-CF3)
H C(CH3)2CH2SCH3 CF3 CH2O(Ph-2-OCF3)
H C(CH3)2CH2SCH3 CF3 CH2O(Ph-3-OCF3)
H C(CH3)2CH2SCH3 CF3 CH2O(Ph-4-OCF3)
H C(CH3)2CH2SCH3 CF3 CF2OPh
H C(CH3)2CH2SCH3 CF3 CF2O(Ph-2-F)
H C(CH3)2CH2SCH3 CF3 CF2O(Ph-3-F)
H C(CH3)2CH2SCH3 CF3 CF2O(Ph-4-F)
H C(CH3)2CH2SCH3 CF3 CF2O(Ph-2-Cl)
H C(CH3)2CH2SCH3 CF3 CF2O(Ph-3-Cl)
H C(CH3)2CH2SCH3 CF3 CF2O(Ph-4-Cl)
H C(CH3)2CH2SCH3 CF3 CF2O(Ph-2-Br)
H C(CH3)2CH2SCH3 CF3 CF2O(Ph-3-Br)
H C(CH3)2CH2SCH3 CF3 CF2O(Ph-4-Br)
H C(CH3)2CH2SCH3 CF3 CF2O(Ph-2-CF3)
H C(CH3)2CH2SCH3 CF3 CF2O(Ph-3-CF3)
H C(CH3)2CH2SCH3 CF3 CF2O(Ph-4-CF3)
H C(CH3)2CH2SCH3 CF3 CF2O(Ph-2-OCF3)
H C(CH3)2CH2SCH3 CF3 CF2O(Ph-3-OCF3)
H C(CH3)2CH2SCH3 CF3 CF2O(Ph-4-OCF3)
H C(CH3)2CH2SCH3 CF3 CH2S(Ph-2-Cl)
H C(CH3)2CH2SCH3 CF3 CH2S(Ph-3-Cl)
H C(CH3)2CH2SCH3 CF3 CH2S(Ph-4-Cl)
H C(CH3)2CH2SCH3 CF3 CH2SO2(Ph-2-Cl)
H C(CH3)2CH2SCH3 CF3 CH2SO2(Ph-3-Cl)
H C(CH3)2CH2SCH3 CF3 CH2SO2(Ph-4-Cl)
H C(CH3)2CH2SCH3 CF3 CH2N(CH3)2
H C(CH3)2CH2SCH3 CF3 CH2NH(Ph-2-Cl)
H C(CH3)2CH2SCH3 CF3 CH2NH(Ph-3-Cl)
H C(CH3)2CH2SCH3 CF3 CH2NH(Ph-4-Cl)
H C(CH3)2CH2SCH3 CF3 CF2C(O)OEt
H C(CH3)2CH2SCH3 CF3 CH2(L-5a)
H C(CH3)2CH2SCH3 CF3 CH2(L-14a)
H C(CH3)2CH2SCH3 CF3 CH2(L-24a)
H C(CH3)2CH2SCH3 CF3 CH2(L-36a)
H C(CH3)2CH2SCH3 CF3 CH2CH2Ph
H C(CH3)2CH2SCH3 CF3 CH2CH2(Ph-2-Cl)
H C(CH3)2CH2SCH3 CF3 CH2CH2(Ph-3-Cl)
H C(CH3)2CH2SCH3 CF3 CH2CH2(Ph-4-Cl)
H C(CH3)2CH2SCH3 CF3 T-22
H C(CH3)2CH2SCH3 CF3 T-23
H C(CH3)2CH2SCH3 CF3 T-24
H C(CH3)2CH2SCH3 CF3 C(O)OEt
H C(CH3)2CH2SCH3 CF3 C(O)OBu-t
H C(CH3)2CH2SCH3 CF3 C(O)OCH2CF3
H C(CH3)2CH2SCH3 CF3 CH=CH(Ph-2-F)
H C(CH3)2CH2SCH3 CF3 CH=CH(Ph-3-F)
H C(CH3)2CH2SCH3 CF3 CH=CH(Ph-4-F)
H C(CH3)2CH2SCH3 CF3 CH=CH(Ph-2-Cl)
H C(CH3)2CH2SCH3 CF3 CH=CH(Ph-3-Cl)
H C(CH3)2CH2SCH3 CF3 CH=CH(Ph-4-Cl)
H C(CH3)2CH2SCH3 CF3 CH=CH(Ph-2-Br)
H C(CH3)2CH2SCH3 CF3 CH=CH(Ph-3-Br)
H C(CH3)2CH2SCH3 CF3 CH=CH(Ph-4-Br)
H C(CH3)2CH2SCH3 CF3 CH=CH(Ph-2-CF3)
H C(CH3)2CH2SCH3 CF3 CH=CH(Ph-3-CF3)
H C(CH3)2CH2SCH3 CF3 CH=CH(Ph-4-CF3)
H C(CH3)2CH2SCH3 CF3 CH=CH(Ph-2-OCF3)
H C(CH3)2CH2SCH3 CF3 CH=CH(Ph-3-OCF3)
H C(CH3)2CH2SCH3 CF3 CH=CH(Ph-4-OCF3)
H C(CH3)2CH2SCH3 CF3 CH=CH(Ph-2-SCH3)
H C(CH3)2CH2SCH3 CF3 CH=CH(Ph-3-SCH3)
H C(CH3)2CH2SCH3 CF3 CH=CH(Ph-4-SCH3)
H C(CH3)2CH2SCH3 CF3 CH=CH(Ph-2-SO2CH3)
H C(CH3)2CH2SCH3 CF3 CH=CH(Ph-3-SO2CH3)
H C(CH3)2CH2SCH3 CF3 CH=CH(Ph-4-SO2CH3)
H C(CH3)2CH2SCH3 CF3 CH=CH(Ph-3,4-F2)
H C(CH3)2CH2SCH3 CF3 CH=CH(Ph-3-F-4-Cl)
H C(CH3)2CH2SCH3 CF3 CH=CH(Ph-3,4-Cl2)
H C(CH3)2CH2SCH3 CF3 CH=CH(Ph-3,4-Br2)
H C(CH3)2CH2SCH3 CF3 CH=CH(Ph-3-F-4-CF3)
H C(CH3)2CH2SCH3 CF3 CH=CH(Ph-3-Cl-4-OCF3)
H C(CH3)2CH2SCH3 CF3 CH=CH[Ph(-3-OCF2O-4-)]
H C(CH3)2CH2SCH3 CF3 Ph
H C(CH3)2CH2SCH3 CF3 Ph-2-F
H C(CH3)2CH2SCH3 CF3 Ph-3-F
H C(CH3)2CH2SCH3 CF3 Ph-4-F
H C(CH3)2CH2SCH3 CF3 Ph-2-Cl
H C(CH3)2CH2SCH3 CF3 Ph-3-Cl
H C(CH3)2CH2SCH3 CF3 Ph-4-Cl
H C(CH3)2CH2SCH3 CF3 Ph-2-Br
H C(CH3)2CH2SCH3 CF3 Ph-3-Br
H C(CH3)2CH2SCH3 CF3 Ph-4-Br
H C(CH3)2CH2SCH3 CF3 Ph-4-I
H C(CH3)2CH2SCH3 CF3 Ph-4-Bu-t
H C(CH3)2CH2SCH3 CF3 Ph-2-CF3
H C(CH3)2CH2SCH3 CF3 Ph-3-CF3
H C(CH3)2CH2SCH3 CF3 Ph-4-CF3
H C(CH3)2CH2SCH3 CF3 Ph-4-OCH3
H C(CH3)2CH2SCH3 CF3 Ph-4-OCHF2
H C(CH3)2CH2SCH3 CF3 Ph-2-OCF3
H C(CH3)2CH2SCH3 CF3 Ph-3-OCF3
H C(CH3)2CH2SCH3 CF3 Ph-4-OCF3
H C(CH3)2CH2SCH3 CF3 Ph-4-OCF2Br
H C(CH3)2CH2SCH3 CF3 Ph-4-OCH2CF3
H C(CH3)2CH2SCH3 CF3 Ph-4-OCF2CHF2
H C(CH3)2CH2SCH3 CF3 Ph-4-OCF2CHFCl
H C(CH3)2CH2SCH3 CF3 Ph-4-OCF2CHFBr
H C(CH3)2CH2SCH3 CF3 Ph-4-OCF2CF2Br
H C(CH3)2CH2SCH3 CF3 Ph-4-OCF2CFCl2
H C(CH3)2CH2SCH3 CF3 Ph-4-OCF2CCl3
H C(CH3)2CH2SCH3 CF3 Ph-4-OCH2CF2CHF2
H C(CH3)2CH2SCH3 CF3 Ph-3-OCF2CHFCF3
H C(CH3)2CH2SCH3 CF3 Ph-4-OCF2CHFCF3
H C(CH3)2CH2SCH3 CF3 Ph-4-OCH(CF3)2
H C(CH3)2CH2SCH3 CF3 Ph-4-OCF2CFBrCF3
H C(CH3)2CH2SCH3 CF3 Ph-3-OCF2CHFOCF3
H C(CH3)2CH2SCH3 CF3 Ph-4-OCF2CHFOCF3
H C(CH3)2CH2SCH3 CF3 Ph-4-OCF2CHFOCF2CF2CF3
H C(CH3)2CH2SCH3 CF3 Ph-4-OSO2CH3
H C(CH3)2CH2SCH3 CF3 Ph-4-OSO2CF3
H C(CH3)2CH2SCH3 CF3 Ph-3-O(Ph-4-Cl)
H C(CH3)2CH2SCH3 CF3 Ph-4-O(Ph-4-Cl)
H C(CH3)2CH2SCH3 CF3 Ph-4-O(Ph-4-Br)
H C(CH3)2CH2SCH3 CF3 Ph-4-O(Ph-4-CF3)
H C(CH3)2CH2SCH3 CF3 Ph-4-O(L-45c)Br
H C(CH3)2CH2SCH3 CF3 Ph-4-O(L-45c)CF3
H C(CH3)2CH2SCH3 CF3 Ph-3-O(L-45e)
H C(CH3)2CH2SCH3 CF3 Ph-4-O(L-45e)
H C(CH3)2CH2SCH3 CF3 Ph-4-O(L-48b)Br
H C(CH3)2CH2SCH3 CF3 Ph-4-SCH3
H C(CH3)2CH2SCH3 CF3 Ph-4-SO2CH3
H C(CH3)2CH2SCH3 CF3 Ph-3-S(Ph-4-Cl)
H C(CH3)2CH2SCH3 CF3 Ph-4-S(Ph-4-Cl)
H C(CH3)2CH2SCH3 CF3 Ph-4-S(Ph-4-Br)
H C(CH3)2CH2SCH3 CF3 Ph-4-S(Ph-4-CF3)
H C(CH3)2CH2SCH3 CF3 Ph-4-S(L-45c)Br
H C(CH3)2CH2SCH3 CF3 Ph-4-S(L-45c)CF3
H C(CH3)2CH2SCH3 CF3 Ph-4-S(L-45e)
H C(CH3)2CH2SCH3 CF3 Ph-4-S(L-48b)Br
H C(CH3)2CH2SCH3 CF3 Ph-4-NO2
H C(CH3)2CH2SCH3 CF3 Ph-4-CN
H C(CH3)2CH2SCH3 CF3 Ph-2,3-F2
H C(CH3)2CH2SCH3 CF3 Ph-2,4-F2
H C(CH3)2CH2SCH3 CF3 Ph-3,4-F2
H C(CH3)2CH2SCH3 CF3 Ph-2,5-F2
H C(CH3)2CH2SCH3 CF3 Ph-3,5-F2
H C(CH3)2CH2SCH3 CF3 Ph-2-Cl-4-F
H C(CH3)2CH2SCH3 CF3 Ph-2-F-3-Cl
H C(CH3)2CH2SCH3 CF3 Ph-3-Cl-4-F
H C(CH3)2CH2SCH3 CF3 Ph-2-F-4-Cl
H C(CH3)2CH2SCH3 CF3 Ph-3-F-4-Cl
H C(CH3)2CH2SCH3 CF3 Ph-2,3-Cl2
H C(CH3)2CH2SCH3 CF3 Ph-2,4-Cl2
H C(CH3)2CH2SCH3 CF3 Ph-2,5-Cl2
H C(CH3)2CH2SCH3 CF3 Ph-3,4-Cl2
H C(CH3)2CH2SCH3 CF3 Ph-3,5-Cl2
H C(CH3)2CH2SCH3 CF3 Ph-3-Br-4-F
H C(CH3)2CH2SCH3 CF3 Ph-2-F-4-Br
H C(CH3)2CH2SCH3 CF3 Ph-2-F-5-Br
H C(CH3)2CH2SCH3 CF3 Ph-3,4-Br2
H C(CH3)2CH2SCH3 CF3 Ph-3,5-Br2
H C(CH3)2CH2SCH3 CF3 Ph-3-CH3-4-F
H C(CH3)2CH2SCH3 CF3 Ph-3-F-4-CH3
H C(CH3)2CH2SCH3 CF3 Ph-2-F-5-CH3
H C(CH3)2CH2SCH3 CF3 Ph-2,4-(CH3)2
H C(CH3)2CH2SCH3 CF3 Ph-3,4-(CH3)2
H C(CH3)2CH2SCH3 CF3 Ph-2-F-3-CF3
H C(CH3)2CH2SCH3 CF3 Ph-3-CF3-4-F
H C(CH3)2CH2SCH3 CF3 Ph-3-CF3-4-Cl
H C(CH3)2CH2SCH3 CF3 Ph-2-F-4-CF3
H C(CH3)2CH2SCH3 CF3 Ph-3-F-4-CF3
H C(CH3)2CH2SCH3 CF3 Ph-2-F-5-CF3
H C(CH3)2CH2SCH3 CF3 Ph-3-F-5-CF3
H C(CH3)2CH2SCH3 CF3 Ph-2-Cl-4-CF3
H C(CH3)2CH2SCH3 CF3 Ph-3,5-(CF3)2
H C(CH3)2CH2SCH3 CF3 Ph-3-Br-4-OCH3
H C(CH3)2CH2SCH3 CF3 Ph-3-F-4-OCHF2
H C(CH3)2CH2SCH3 CF3 Ph-3-Cl-4-OCHF2
H C(CH3)2CH2SCH3 CF3 Ph-3-Br-4-OCHF2
H C(CH3)2CH2SCH3 CF3 Ph-3-F-4-OCF3
H C(CH3)2CH2SCH3 CF3 Ph-3-Cl-4-OCF3
H C(CH3)2CH2SCH3 CF3 Ph-3-Br-4-OCF3
H C(CH3)2CH2SCH3 CF3 Ph-3-F-4-OCF2Br
H C(CH3)2CH2SCH3 CF3 Ph-3-Cl-4-OCF2Br
H C(CH3)2CH2SCH3 CF3 Ph-3-Br-4-OCF2Br
H C(CH3)2CH2SCH3 CF3 Ph-3-F-4-OCF2CHF2
H C(CH3)2CH2SCH3 CF3 Ph-3-Cl-4-OCF2CHF2
H C(CH3)2CH2SCH3 CF3 Ph-3-Br-4-OCF2CHF2
H C(CH3)2CH2SCH3 CF3 Ph-3-F-4-OCF2CHFCl
H C(CH3)2CH2SCH3 CF3 Ph-3-Cl-4-OCF2CHFCl
H C(CH3)2CH2SCH3 CF3 Ph-3-Br-4-OCF2CHFCl
H C(CH3)2CH2SCH3 CF3 Ph-3-F-4-OCF2CHFCF3
H C(CH3)2CH2SCH3 CF3 Ph-3-Cl-4-OCF2CHFCF3
H C(CH3)2CH2SCH3 CF3 Ph-3-Br-4-OCF2CHFCF3
H C(CH3)2CH2SCH3 CF3 Ph-3-F-4-OCF2CHFOCF3
H C(CH3)2CH2SCH3 CF3 Ph-3-Cl-4-OCF2CHFOCF3
H C(CH3)2CH2SCH3 CF3 Ph-3-Br-4-OCF2CHFOCF3
H C(CH3)2CH2SCH3 CF3 Ph-3-CH3-4-OCF2CHFOCF3
H C(CH3)2CH2SCH3 CF3 Ph-3-F-4-OCF2CHFOCF2CF2CF3
H C(CH3)2CH2SCH3 CF3 Ph-3-Cl-4-OCF2CHFOCF2CF2CF3
H C(CH3)2CH2SCH3 CF3 Ph-3-Br-4-OCF2CHFOCF2CF2CF3
H C(CH3)2CH2SCH3 CF3 Ph(-3-OCF2O-4-)
H C(CH3)2CH2SCH3 CF3 Ph(-3-OCF2CF2O-4-)
H C(CH3)2CH2SCH3 CF3 Ph-3-OPh-4-F
H C(CH3)2CH2SCH3 CF3 Ph-3-NO2-4-F
H C(CH3)2CH2SCH3 CF3 Ph-3-NO2-4-Cl
H C(CH3)2CH2SCH3 CF3 Ph-2-F-5-NO2
H C(CH3)2CH2SCH3 CF3 Ph-3-CN-4-F
H C(CH3)2CH2SCH3 CF3 Ph-2,3,4-F3
H C(CH3)2CH2SCH3 CF3 Ph-2,3,5-F3
H C(CH3)2CH2SCH3 CF3 Ph-2,4,5-F3
H C(CH3)2CH2SCH3 CF3 Ph-3,4,5-F3
H C(CH3)2CH2SCH3 CF3 Ph-2,3-F2-4-CH3
H C(CH3)2CH2SCH3 CF3 Ph-2,3-F2-4-CF3
H C(CH3)2CH2SCH3 CF3 Ph-3,4-F2-5-CF3
H C(CH3)2CH2SCH3 CF3 Ph-2-F-3-Cl-5-CF3
H C(CH3)2CH2SCH3 CF3 Ph-3,5-Cl2-4-OCH3
H C(CH3)2CH2SCH3 CF3 1-Naph
H C(CH3)2CH2SCH3 CF3 2-Naph
H C(CH3)2CH2SCH3 CF3 (L-1b)Br
H C(CH3)2CH2SCH3 CF3 (L-1c)Cl
H C(CH3)2CH2SCH3 CF3 (L-1c)Br
H C(CH3)2CH2SCH3 CF3 (L-1c)I
H C(CH3)2CH2SCH3 CF3 (L-1c)CF3
H C(CH3)2CH2SCH3 CF3 (L-2b)Br
H C(CH3)2CH2SCH3 CF3 (L-3b)Cl
H C(CH3)2CH2SCH3 CF3 (L-3b)Br
H C(CH3)2CH2SCH3 CF3 (L-3c)F
H C(CH3)2CH2SCH3 CF3 (L-3c)Cl
H C(CH3)2CH2SCH3 CF3 (L-3c)Br
H C(CH3)2CH2SCH3 CF3 (L-3c)I
H C(CH3)2CH2SCH3 CF3 (L-3c)CF3
H C(CH3)2CH2SCH3 CF3 (L-3c)CN
H C(CH3)2CH2SCH3 CF3 L-3d
H C(CH3)2CH2SCH3 CF3 (L-4b)Cl
H C(CH3)2CH2SCH3 CF3 (L-4b)Br
H C(CH3)2CH2SCH3 CF3 (L-4b)CN
H C(CH3)2CH2SCH3 CF3 (L-10b)Cl
H C(CH3)2CH2SCH3 CF3 (L-10b)Br
H C(CH3)2CH2SCH3 CF3 (L-15b)CF3
H C(CH3)2CH2SCH3 CF3 (L-16a)CHF2
H C(CH3)2CH2SCH3 CF3 (L-16a)CF2Br
H C(CH3)2CH2SCH3 CF3 (L-17a)Cl
H C(CH3)2CH2SCH3 CF3 (L-21b)Cl
H C(CH3)2CH2SCH3 CF3 (L-21b)Br
H C(CH3)2CH2SCH3 CF3 (L-21b)I
H C(CH3)2CH2SCH3 CF3 (L-21b)CF3
H C(CH3)2CH2SCH3 CF3 (L-22b)Cl
H C(CH3)2CH2SCH3 CF3 (L-22b)Br
H C(CH3)2CH2SCH3 CF3 (L-23b)Cl
H C(CH3)2CH2SCH3 CF3 (L-23b)Br
H C(CH3)2CH2SCH3 CF3 (L-23c)Cl
H C(CH3)2CH2SCH3 CF3 (L-23c)Br
H C(CH3)2CH2SCH3 CF3 (L-31a)Cl
H C(CH3)2CH2SCH3 CF3 (L-31a)Br
H C(CH3)2CH2SCH3 CF3 (L-45c)F
H C(CH3)2CH2SCH3 CF3 (L-45c)Cl
H C(CH3)2CH2SCH3 CF3 (L-45c)Br
H C(CH3)2CH2SCH3 CF3 (L-45c)I
H C(CH3)2CH2SCH3 CF3 (L-45c)CF3
H C(CH3)2CH2SCH3 CF3 L-45e
H C(CH3)2CH2SCH3 CF3 L-45f
H C(CH3)2CH2SCH3 CF3 (L-46c)F
H C(CH3)2CH2SCH3 CF3 (L-46c)Cl
H C(CH3)2CH2SCH3 CF3 (L-46c)Br
H C(CH3)2CH2SCH3 CF3 (L-46c)I
H C(CH3)2CH2SCH3 CF3 (L-46c)CF3
H C(CH3)2CH2SCH3 CF3 (L-46c)OCH2CF3
H C(CH3)2CH2SCH3 CF3 (L-46c)OCH(CF3)2
H C(CH3)2CH2SCH3 CF3 L-46d
H C(CH3)2CH2SCH3 CF3 L-47a
H C(CH3)2CH2SCH3 CF3 L-47d
H C(CH3)2CH2SCH3 CF3 (L-48b)Br
H C(CH3)2CH2SCH3 CF3 (L-50b)Cl
H C(CH3)2CH2SCH3 CF3 (L-50b)Br
H C(CH3)2CH2SCH3 CF3 (L-51b)Cl
H C(CH3)2CH2SCH3 CF2Cl Ph-4-Cl
H C(CH3)2CH2SCH3 CF2Cl Ph-4-Br
H C(CH3)2CH2SCH3 CF2Cl Ph-4-CF3
H C(CH3)2CH2SCH3 CF2Cl Ph-4-OCF3
H C(CH3)2CH2SCH3 CF2Cl Ph-4-OCF2Br
H C(CH3)2CH2SCH3 CF2Cl Ph-4-OCF2CHFCF3
H C(CH3)2CH2SCH3 CF2Cl Ph-4-OCF2CHFOCF3
H C(CH3)2CH2SCH3 CF2Cl Ph-4-OCF2CHFOCF2CF2CF3
H C(CH3)2CH2SCH3 CF2Cl Ph-4-O(L-45g)
H C(CH3)2CH2SCH3 CF2Cl Ph-3,4-Cl2
H C(CH3)2CH2SCH3 CF2Cl Ph(-3-OCF2O-4-)
H C(CH3)2CH2SCH3 CF2Cl Ph(-3-OCF2CF2O-4-)
H C(CH3)2CH2SCH3 CF2Cl (L-45c)CF3
H C(CH3)2CH2SCH3 CF2Cl L-45f
H C(CH3)2CH2SCH3 CF2Cl (L-46c)CF3
H C(CH3)2CH2SCH3 CF2Cl L-46d
H C(CH3)2CH2SCH3 CFCl2 Ph-4-OCF3
H C(CH3)2CH2SCH3 CF2Br Ph-4-Cl
H C(CH3)2CH2SCH3 CF2Br Ph-4-Br
H C(CH3)2CH2SCH3 CF2Br Ph-4-CF3
H C(CH3)2CH2SCH3 CF2Br Ph-4-OCF3
H C(CH3)2CH2SCH3 CF2Br Ph-4-OCF2Br
H C(CH3)2CH2SCH3 CF2Br Ph-4-OCF2CHFCF3
H C(CH3)2CH2SCH3 CF2Br Ph-4-OCF2CHFOCF3
H C(CH3)2CH2SCH3 CF2Br Ph-4-OCF2CHFOCF2CF2CF3
H C(CH3)2CH2SCH3 CF2Br Ph-4-O(L-45g)
H C(CH3)2CH2SCH3 CF2Br Ph-3,4-Cl2
H C(CH3)2CH2SCH3 CF2Br Ph(-3-OCF2O-4-)
H C(CH3)2CH2SCH3 CF2Br Ph(-3-OCF2CF2O-4-)
H C(CH3)2CH2SCH3 CF2Br (L-45c)CF3
H C(CH3)2CH2SCH3 CF2Br L-45f
H C(CH3)2CH2SCH3 CF2Br (L-46c)CF3
H C(CH3)2CH2SCH3 CF2Br L-46d
H C(CH3)2CH2SCH3 CFClBr (L-45c)CF3
H C(CH3)2CH2SCH3 CFBr2 Ph-4-Br
H C(CH3)2CH2SCH3 CF2CHF2 Ph-4-CF3
H C(CH3)2CH2SCH3 CF2CF3 Ph-4-Cl
H C(CH3)2CH2SCH3 CF2CF3 Ph-4-Br
H C(CH3)2CH2SCH3 CF2CF3 Ph-4-CF3
H C(CH3)2CH2SCH3 CF2CF3 Ph-4-OCF3
H C(CH3)2CH2SCH3 CF2CF3 Ph-4-OCF2Br
H C(CH3)2CH2SCH3 CF2CF3 Ph-4-OCF2CHFCF3
H C(CH3)2CH2SCH3 CF2CF3 Ph-4-OCF2CHFOCF3
H C(CH3)2CH2SCH3 CF2CF3 Ph-4-OCF2CHFOCF2CF2CF3
H C(CH3)2CH2SCH3 CF2CF3 Ph-4-O(L-45g)
H C(CH3)2CH2SCH3 CF2CF3 Ph-3,4-Cl2
H C(CH3)2CH2SCH3 CF2CF3 Ph(-3-OCF2O-4-)
H C(CH3)2CH2SCH3 CF2CF3 Ph(-3-OCF2CF2O-4-)
H C(CH3)2CH2SCH3 CF2CF3 (L-45c)CF3
H C(CH3)2CH2SCH3 CF2CF3 L-45f
H C(CH3)2CH2SCH3 CF2CF3 (L-46c)CF3
H C(CH3)2CH2SCH3 CF2CF3 L-46d
H C(CH3)2CH2SCH3 CF2CF2Cl Ph-4-OCF3
H C(CH3)2CH2SCH3 CFClCF3 (L-45c)CF3
H C(CH3)2CH2SCH3 CFClCF2Cl Ph-4-Br
H C(CH3)2CH2SCH3 CF2CF2Br Ph-4-CF3
H C(CH3)2CH2SCH3 CFBrCF3 Ph-4-OCF3
H C(CH3)2CH2SCH3 CF2CHFCF3 (L-45c)CF3
H C(CH3)2CH2SCH3 CF2CF2CF3 Ph-4-Cl
H C(CH3)2CH2SCH3 CF2CF2CF3 Ph-4-Br
H C(CH3)2CH2SCH3 CF2CF2CF3 Ph-4-CF3
H C(CH3)2CH2SCH3 CF2CF2CF3 Ph-4-OCF3
H C(CH3)2CH2SCH3 CF2CF2CF3 Ph-4-OCF2Br
H C(CH3)2CH2SCH3 CF2CF2CF3 Ph-4-OCF2CHFCF3
H C(CH3)2CH2SCH3 CF2CF2CF3 Ph-4-OCF2CHFOCF3
H C(CH3)2CH2SCH3 CF2CF2CF3 Ph-4-OCF2CHFOCF2CF2CF3
H C(CH3)2CH2SCH3 CF2CF2CF3 Ph-4-O(L-45g)
H C(CH3)2CH2SCH3 CF2CF2CF3 Ph-3,4-Cl2
H C(CH3)2CH2SCH3 CF2CF2CF3 Ph(-3-OCF2O-4-)
H C(CH3)2CH2SCH3 CF2CF2CF3 Ph(-3-OCF2CF2O-4-)
H C(CH3)2CH2SCH3 CF2CF2CF3 (L-45c)CF3
H C(CH3)2CH2SCH3 CF2CF2CF3 L-45f
H C(CH3)2CH2SCH3 CF2CF2CF3 (L-46c)CF3
H C(CH3)2CH2SCH3 CF2CF2CF3 L-46d
H C(CH3)2CH2SCH3 CF(CF3)2 Ph-4-Br
H C(CH3)2CH2SCH3 CF2CF2CF2CF3 Ph-4-CF3
H C(CH3)2CH2SCH3 T-1 Ph-4-OCF3
H C(CH3)2CH2SCH3 T-2 (L-45c)CF3
H C(CH3)2CH2SCH3 CH2OCH3 Ph-4-Br
H C(CH3)2CH2SCH3 CH2OEt Ph-4-CF3
H C(CH3)2CH2SCH3 CH2OCH2CF3 Ph-4-OCF3
H C(CH3)2CH2SCH3 CH2OCH(CF3)2 (L-45c)CF3
H C(CH3)2CH2SCH3 CF2OCH3 Ph-4-Cl
H C(CH3)2CH2SCH3 CF2OCH3 Ph-4-Br
H C(CH3)2CH2SCH3 CF2OCH3 Ph-4-CF3
H C(CH3)2CH2SCH3 CF2OCH3 Ph-4-OCF3
H C(CH3)2CH2SCH3 CF2OCH3 Ph-4-OCF2Br
H C(CH3)2CH2SCH3 CF2OCH3 Ph-4-OCF2CHFCF3
H C(CH3)2CH2SCH3 CF2OCH3 Ph-4-OCF2CHFOCF3
H C(CH3)2CH2SCH3 CF2OCH3 Ph-4-OCF2CHFOCF2CF2CF3
H C(CH3)2CH2SCH3 CF2OCH3 Ph-4-O(L-45g)
H C(CH3)2CH2SCH3 CF2OCH3 Ph-3,4-Cl2
H C(CH3)2CH2SCH3 CF2OCH3 Ph(-3-OCF2O-4-)
H C(CH3)2CH2SCH3 CF2OCH3 Ph(-3-OCF2CF2O-4-)
H C(CH3)2CH2SCH3 CF2OCH3 (L-45c)CF3
H C(CH3)2CH2SCH3 CF2OCH3 L-45f
H C(CH3)2CH2SCH3 CF2OCH3 (L-46c)CF3
H C(CH3)2CH2SCH3 CF2OCH3 L-46d
H C(CH3)2CH2SCH3 CH2SCH3 Ph-4-Br
H C(CH3)2CH2SCH3 CH2SO2CH3 Ph-4-CF3
H C(CH3)2CH2SCH3 CH2SCF3 Ph-4-OCF3
H C(CH3)2CH2SCH3 CF2SCH3 Ph-4-Cl
H C(CH3)2CH2SCH3 CF2SCH3 Ph-4-Br
H C(CH3)2CH2SCH3 CF2SCH3 Ph-4-CF3
H C(CH3)2CH2SCH3 CF2SCH3 Ph-4-OCF3
H C(CH3)2CH2SCH3 CF2SCH3 Ph-4-OCF2Br
H C(CH3)2CH2SCH3 CF2SCH3 Ph-4-OCF2CHFCF3
H C(CH3)2CH2SCH3 CF2SCH3 Ph-4-OCF2CHFOCF3
H C(CH3)2CH2SCH3 CF2SCH3 Ph-4-OCF2CHFOCF2CF2CF3
H C(CH3)2CH2SCH3 CF2SCH3 Ph-4-O(L-45g)
H C(CH3)2CH2SCH3 CF2SCH3 Ph-3,4-Cl2
H C(CH3)2CH2SCH3 CF2SCH3 Ph(-3-OCF2O-4-)
H C(CH3)2CH2SCH3 CF2SCH3 Ph(-3-OCF2CF2O-4-)
H C(CH3)2CH2SCH3 CF2SCH3 (L-45c)CF3
H C(CH3)2CH2SCH3 CF2SCH3 L-45f
H C(CH3)2CH2SCH3 CF2SCH3 (L-46c)CF3
H C(CH3)2CH2SCH3 CF2SCH3 L-46d
H C(CH3)2CH2SCH3 CF2SEt (L-45c)CF3
H C(CH3)2CH2SCH3 CF2SPr-n Ph-4-Br
H C(CH3)2CH2SCH3 CF2SPr-i Ph-4-CF3
H C(CH3)2CH2SCH3 CF2SCH2Ph Ph-4-OCF3
H C(CH3)2CH2SCH3 CF2SPh (L-45c)CF3
H C(CH3)2CH2SCH3 CF2C(O)OEt Ph-4-Br
H C(CH3)2CH2SCH3 CF2SO2N(CH3)2 Ph-4-CF3
H C(CH3)2CH2SCH3 C(O)OEt Ph-4-OCF3
H C(CH3)2CH2SCH3 C(O)SEt (L-45c)CF3
H C(CH3)2CH2S(O)CH3 CH3 Ph-4-Br
H C(CH3)2CH2S(O)CH3 CH3 Ph-4-CF3
H C(CH3)2CH2S(O)CH3 CH3 Ph-4-OCF3
H C(CH3)2CH2S(O)CH3 CH3 (L-45c)CF3
H C(CH3)2CH2S(O)CH3 CF3 CH2O(Ph-4-Cl)
H C(CH3)2CH2S(O)CH3 CF3 CH2O(Ph-4-Br)
H C(CH3)2CH2S(O)CH3 CF3 CH2O(Ph-4-CF3)
H C(CH3)2CH2S(O)CH3 CF3 CH2O(Ph-4-OCF3)
H C(CH3)2CH2S(O)CH3 CF3 CF2O(Ph-4-Cl)
H C(CH3)2CH2S(O)CH3 CF3 CF2O(Ph-4-Br)
H C(CH3)2CH2S(O)CH3 CF3 CF2O(Ph-4-CF3)
H C(CH3)2CH2S(O)CH3 CF3 CF2O(Ph-4-OCF3)
H C(CH3)2CH2S(O)CH3 CF3 CH=CH(Ph-4-F)
H C(CH3)2CH2S(O)CH3 CF3 CH=CH(Ph-4-Cl)
H C(CH3)2CH2S(O)CH3 CF3 CH=CH(Ph-4-Br)
H C(CH3)2CH2S(O)CH3 CF3 CH=CH(Ph-4-CF3)
H C(CH3)2CH2S(O)CH3 CF3 CH=CH(Ph-4-OCF3)
H C(CH3)2CH2S(O)CH3 CF3 CH=CH(Ph-4-SCH3)
H C(CH3)2CH2S(O)CH3 CF3 CH=CH(Ph-4-SO2CH3)
H C(CH3)2CH2S(O)CH3 CF3 CH=CH(Ph-3,4-Cl2)
H C(CH3)2CH2S(O)CH3 CF3 Ph-4-F
H C(CH3)2CH2S(O)CH3 CF3 Ph-2-Cl
H C(CH3)2CH2S(O)CH3 CF3 Ph-3-Cl
H C(CH3)2CH2S(O)CH3 CF3 Ph-4-Cl
H C(CH3)2CH2S(O)CH3 CF3 Ph-4-Br
H C(CH3)2CH2S(O)CH3 CF3 Ph-4-I
H C(CH3)2CH2S(O)CH3 CF3 Ph-4-CF3
H C(CH3)2CH2S(O)CH3 CF3 Ph-4-OCHF2
H C(CH3)2CH2S(O)CH3 CF3 Ph-4-OCF3
H C(CH3)2CH2S(O)CH3(-) CF3 Ph-4-OCF3
H C(CH3)2CH2S(O)CH3(+) CF3 Ph-4-OCF3
H C(CH3)2CH2S(O)CH3 CF3 Ph-4-OCF2Br
H C(CH3)2CH2S(O)CH3 CF3 Ph-4-OCH2CF3
H C(CH3)2CH2S(O)CH3 CF3 Ph-4-OCF2CHF2
H C(CH3)2CH2S(O)CH3 CF3 Ph-4-OCF2CHFCl
H C(CH3)2CH2S(O)CH3 CF3 Ph-4-OCF2CHFCF3
H C(CH3)2CH2S(O)CH3 CF3 Ph-4-OCF2CHFOCF3
H C(CH3)2CH2S(O)CH3 CF3 Ph-4-OCF2CHFOCF2CF2CF3
H C(CH3)2CH2S(O)CH3 CF3 Ph-4-OSO2CH3
H C(CH3)2CH2S(O)CH3 CF3 Ph-4-OSO2CF3
H C(CH3)2CH2S(O)CH3 CF3 Ph-4-O(L-45e)
H C(CH3)2CH2S(O)CH3 CF3 Ph-2,4-F2
H C(CH3)2CH2S(O)CH3 CF3 Ph-3,4-F2
H C(CH3)2CH2S(O)CH3 CF3 Ph-3-Cl-4-F
H C(CH3)2CH2S(O)CH3 CF3 Ph-2-F-4-Cl
H C(CH3)2CH2S(O)CH3 CF3 Ph-3-F-4-Cl
H C(CH3)2CH2S(O)CH3 CF3 Ph-2,4-Cl2
H C(CH3)2CH2S(O)CH3 CF3 Ph-3,4-Cl2
H C(CH3)2CH2S(O)CH3 CF3 Ph-3,5-Cl2
H C(CH3)2CH2S(O)CH3 CF3 Ph-3-Br-4-F
H C(CH3)2CH2S(O)CH3 CF3 Ph-2-F-4-Br
H C(CH3)2CH2S(O)CH3 CF3 Ph-3,4-Br2
H C(CH3)2CH2S(O)CH3 CF3 Ph-3-CH3-4-F
H C(CH3)2CH2S(O)CH3 CF3 Ph-3-CF3-4-F
H C(CH3)2CH2S(O)CH3 CF3 Ph-3-CF3-4-Cl
H C(CH3)2CH2S(O)CH3 CF3 Ph-2-F-4-CF3
H C(CH3)2CH2S(O)CH3 CF3 Ph-3-F-4-CF3
H C(CH3)2CH2S(O)CH3 CF3 Ph-2-Cl-4-CF3
H C(CH3)2CH2S(O)CH3 CF3 Ph-3-F-4-OCHF2
H C(CH3)2CH2S(O)CH3 CF3 Ph-3-Cl-4-OCHF2
H C(CH3)2CH2S(O)CH3 CF3 Ph-3-Br-4-OCHF2
H C(CH3)2CH2S(O)CH3 CF3 Ph-3-F-4-OCF3
H C(CH3)2CH2S(O)CH3 CF3 Ph-3-Cl-4-OCF3
H C(CH3)2CH2S(O)CH3 CF3 Ph-3-Br-4-OCF3
H C(CH3)2CH2S(O)CH3 CF3 Ph-3-F-4-OCF2Br
H C(CH3)2CH2S(O)CH3 CF3 Ph-3-Cl-4-OCF2Br
H C(CH3)2CH2S(O)CH3 CF3 Ph-3-Br-4-OCF2Br
H C(CH3)2CH2S(O)CH3 CF3 Ph-3-F-4-OCF2CHF2
H C(CH3)2CH2S(O)CH3 CF3 Ph-3-Cl-4-OCF2CHF2
H C(CH3)2CH2S(O)CH3 CF3 Ph-3-Br-4-OCF2CHF2
H C(CH3)2CH2S(O)CH3 CF3 Ph-3-F-4-OCF2CHFCl
H C(CH3)2CH2S(O)CH3 CF3 Ph-3-Cl-4-OCF2CHFCl
H C(CH3)2CH2S(O)CH3 CF3 Ph-3-Br-4-OCF2CHFCl
H C(CH3)2CH2S(O)CH3 CF3 Ph-3-F-4-OCF2CHFCF3
H C(CH3)2CH2S(O)CH3 CF3 Ph-3-Cl-4-OCF2CHFCF3
H C(CH3)2CH2S(O)CH3 CF3 Ph-3-Br-4-OCF2CHFCF3
H C(CH3)2CH2S(O)CH3 CF3 Ph-3-F-4-OCF2CHFOCF3
H C(CH3)2CH2S(O)CH3 CF3 Ph-3-Cl-4-OCF2CHFOCF3
H C(CH3)2CH2S(O)CH3 CF3 Ph-3-Br-4-OCF2CHFOCF3
H C(CH3)2CH2S(O)CH3 CF3 Ph-3-CH3-4-OCF2CHFOCF3
H C(CH3)2CH2S(O)CH3 CF3 Ph-3-F-4-OCF2CHFOCF2CF2CF3
H C(CH3)2CH2S(O)CH3 CF3 Ph-3-Cl-4-OCF2CHFOCF2CF2CF3
H C(CH3)2CH2S(O)CH3 CF3 Ph-3-Br-4-OCF2CHFOCF2CF2CF3
H C(CH3)2CH2S(O)CH3 CF3 Ph(-3-OCF2O-4-)
H C(CH3)2CH2S(O)CH3 CF3 Ph(-3-OCF2CF2O-4-)
H C(CH3)2CH2S(O)CH3 CF3 Ph-3,4-F2-5-CF3
H C(CH3)2CH2S(O)CH3 CF3 2-Naph
H C(CH3)2CH2S(O)CH3 CF3 (L-1b)Br
H C(CH3)2CH2S(O)CH3 CF3 (L-1c)Cl
H C(CH3)2CH2S(O)CH3 CF3 (L-1c)Br
H C(CH3)2CH2S(O)CH3 CF3 (L-1c)CF3
H C(CH3)2CH2S(O)CH3 CF3 (L-2b)Br
H C(CH3)2CH2S(O)CH3 CF3 (L-3b)Cl
H C(CH3)2CH2S(O)CH3 CF3 (L-3b)Br
H C(CH3)2CH2S(O)CH3 CF3 (L-3c)Cl
H C(CH3)2CH2S(O)CH3 CF3 (L-3c)Br
H C(CH3)2CH2S(O)CH3 CF3 (L-3c)CF3
H C(CH3)2CH2S(O)CH3 CF3 L-3d
H C(CH3)2CH2S(O)CH3 CF3 (L-4b)Cl
H C(CH3)2CH2S(O)CH3 CF3 (L-4b)Br
H C(CH3)2CH2S(O)CH3 CF3 (L-10b)Cl
H C(CH3)2CH2S(O)CH3 CF3 (L-10b)Br
H C(CH3)2CH2S(O)CH3 CF3 (L-15b)CF3
H C(CH3)2CH2S(O)CH3 CF3 (L-16a)CHF2
H C(CH3)2CH2S(O)CH3 CF3 (L-16a)CF2Br
H C(CH3)2CH2S(O)CH3 CF3 (L-17a)Cl
H C(CH3)2CH2S(O)CH3 CF3 (L-21b)Cl
H C(CH3)2CH2S(O)CH3 CF3 (L-21b)Br
H C(CH3)2CH2S(O)CH3 CF3 (L-21b)CF3
H C(CH3)2CH2S(O)CH3 CF3 (L-22b)Cl
H C(CH3)2CH2S(O)CH3 CF3 (L-22b)Br
H C(CH3)2CH2S(O)CH3 CF3 (L-23b)Cl
H C(CH3)2CH2S(O)CH3 CF3 (L-23b)Br
H C(CH3)2CH2S(O)CH3 CF3 (L-23c)Cl
H C(CH3)2CH2S(O)CH3 CF3 (L-23c)Br
H C(CH3)2CH2S(O)CH3 CF3 (L-31a)Cl
H C(CH3)2CH2S(O)CH3 CF3 (L-31a)Br
H C(CH3)2CH2S(O)CH3 CF3 (L-45c)F
H C(CH3)2CH2S(O)CH3 CF3 (L-45c)Cl
H C(CH3)2CH2S(O)CH3 CF3 (L-45c)Br
H C(CH3)2CH2S(O)CH3 CF3 (L-45c)CF3
H C(CH3)2CH2S(O)CH3 CF3 L-45e
H C(CH3)2CH2S(O)CH3 CF3 L-45f
H C(CH3)2CH2S(O)CH3 CF3 (L-46c)F
H C(CH3)2CH2S(O)CH3 CF3 (L-46c)Cl
H C(CH3)2CH2S(O)CH3 CF3 (L-46c)Br
H C(CH3)2CH2S(O)CH3 CF3 (L-46c)CF3
H C(CH3)2CH2S(O)CH3 CF3 L-46d
H C(CH3)2CH2S(O)CH3 CF3 L-47a
H C(CH3)2CH2S(O)CH3 CF3 L-47d
H C(CH3)2CH2S(O)CH3 CF3 (L-48b)Br
H C(CH3)2CH2S(O)CH3 CF3 (L-50b)Cl
H C(CH3)2CH2S(O)CH3 CF3 (L-50b)Br
H C(CH3)2CH2S(O)CH3 CF3 (L-51b)Cl
H C(CH3)2CH2SO2CH3 CH3 CF2O(Ph-4-Cl)
H C(CH3)2CH2SO2CH3 CH3 CH=CH(Ph-4-Cl)
H C(CH3)2CH2SO2CH3 CH3 CH=CH(Ph-4-OCF3)
H C(CH3)2CH2SO2CH3 CH3 CH=CH(Ph-3,4-Cl2)
H C(CH3)2CH2SO2CH3 CH3 Ph-4-F
H C(CH3)2CH2SO2CH3 CH3 Ph-4-Cl
H C(CH3)2CH2SO2CH3 CH3 Ph-4-Br
H C(CH3)2CH2SO2CH3 CH3 Ph-4-I
H C(CH3)2CH2SO2CH3 CH3 Ph-4-CF3
H C(CH3)2CH2SO2CH3 CH3 Ph-4-OCHF2
H C(CH3)2CH2SO2CH3 CH3 Ph-4-OCF3
H C(CH3)2CH2SO2CH3 CH3 Ph-4-OCF2Br
H C(CH3)2CH2SO2CH3 CH3 Ph-4-OCF2CHF2
H C(CH3)2CH2SO2CH3 CH3 Ph-4-OCF2CHFCl
H C(CH3)2CH2SO2CH3 CH3 Ph-4-OCF2CHFCF3
H C(CH3)2CH2SO2CH3 CH3 Ph-4-OCF2CHFOCF3
H C(CH3)2CH2SO2CH3 CH3 Ph-4-OCF2CHFOCF2CF2CF3
H C(CH3)2CH2SO2CH3 CH3 Ph-4-O(L-45g)
H C(CH3)2CH2SO2CH3 CH3 Ph-3,4-Cl2
H C(CH3)2CH2SO2CH3 CH3 Ph(-3-OCF2O-4-)
H C(CH3)2CH2SO2CH3 CH3 Ph(-3-OCF2CF2O-4-)
H C(CH3)2CH2SO2CH3 CH3 (L-45c)Cl
H C(CH3)2CH2SO2CH3 CH3 (L-45c)Br
H C(CH3)2CH2SO2CH3 CH3 (L-45c)CF3
H C(CH3)2CH2SO2CH3 CH3 L-45e
H C(CH3)2CH2SO2CH3 CH3 L-45f
H C(CH3)2CH2SO2CH3 CH3 (L-46c)Cl
H C(CH3)2CH2SO2CH3 CH3 (L-46c)Br
H C(CH3)2CH2SO2CH3 CH3 (L-46c)CF3
H C(CH3)2CH2SO2CH3 CH3 L-46d
H C(CH3)2CH2SO2CH3 Et Ph-4-Cl
H C(CH3)2CH2SO2CH3 Et Ph-4-Br
H C(CH3)2CH2SO2CH3 Et Ph-4-CF3
H C(CH3)2CH2SO2CH3 Et Ph-4-OCF3
H C(CH3)2CH2SO2CH3 Et Ph-4-OCF2Br
H C(CH3)2CH2SO2CH3 Et Ph-4-OCF2CHFCF3
H C(CH3)2CH2SO2CH3 Et Ph-4-OCF2CHFOCF3
H C(CH3)2CH2SO2CH3 Et Ph-4-OCF2CHFOCF2CF2CF3
H C(CH3)2CH2SO2CH3 Et Ph-4-O(L-45g)
H C(CH3)2CH2SO2CH3 Et Ph-3,4-Cl2
H C(CH3)2CH2SO2CH3 Et Ph(-3-OCF2O-4-)
H C(CH3)2CH2SO2CH3 Et Ph(-3-OCF2CF2O-4-)
H C(CH3)2CH2SO2CH3 Et (L-45c)CF3
H C(CH3)2CH2SO2CH3 n-Pr Ph-4-Br
H C(CH3)2CH2SO2CH3 n-Pr Ph-4-CF3
H C(CH3)2CH2SO2CH3 n-Pr Ph-4-OCF3
H C(CH3)2CH2SO2CH3 n-Pr (L-45c)CF3
H C(CH3)2CH2SO2CH3 i-Pr Ph-4-Br
H C(CH3)2CH2SO2CH3 i-Pr Ph-4-CF3
H C(CH3)2CH2SO2CH3 i-Pr Ph-4-OCF3
H C(CH3)2CH2SO2CH3 i-Pr (L-45c)CF3
H C(CH3)2CH2SO2CH3 c-Pr Ph-4-Br
H C(CH3)2CH2SO2CH3 c-Pr Ph-4-CF3
H C(CH3)2CH2SO2CH3 c-Pr Ph-4-OCF3
H C(CH3)2CH2SO2CH3 c-Pr (L-45c)CF3
H C(CH3)2CH2SO2CH3 n-Bu Ph-4-OCF3
H C(CH3)2CH2SO2CH3 CH2F (L-45c)CF3
H C(CH3)2CH2SO2CH3 CH2Cl Ph-4-Br
H C(CH3)2CH2SO2CH3 CH2Br Ph-4-CF3
H C(CH3)2CH2SO2CH3 CHF2 Ph-4-Cl
H C(CH3)2CH2SO2CH3 CHF2 Ph-4-Br
H C(CH3)2CH2SO2CH3 CHF2 Ph-4-CF3
H C(CH3)2CH2SO2CH3 CHF2 Ph-4-OCF3
H C(CH3)2CH2SO2CH3 CHF2 Ph-4-OCF2Br
H C(CH3)2CH2SO2CH3 CHF2 Ph-4-OCF2CHFCF3
H C(CH3)2CH2SO2CH3 CHF2 Ph-4-OCF2CHFOCF3
H C(CH3)2CH2SO2CH3 CHF2 Ph-4-OCF2CHFOCF2CF2CF3
H C(CH3)2CH2SO2CH3 CHF2 Ph-4-O(L-45g)
H C(CH3)2CH2SO2CH3 CHF2 Ph-3,4-Cl2
H C(CH3)2CH2SO2CH3 CHF2 Ph(-3-OCF2O-4-)
H C(CH3)2CH2SO2CH3 CHF2 Ph(-3-OCF2CF2O-4-)
H C(CH3)2CH2SO2CH3 CHF2 (L-45c)CF3
H C(CH3)2CH2SO2CH3 CHF2 L-45f
H C(CH3)2CH2SO2CH3 CHF2 (L-46c)CF3
H C(CH3)2CH2SO2CH3 CHF2 L-46d
H C(CH3)2CH2SO2CH3 CHFCl Ph-4-OCF3
H C(CH3)2CH2SO2CH3 CHFBr (L-45c)CF3
H C(CH3)2CH2SO2CH3 CF3 c-Pr
H C(CH3)2CH2SO2CH3 CF3 c-Bu
H C(CH3)2CH2SO2CH3 CF3 c-Pen
H C(CH3)2CH2SO2CH3 CF3 c-Hex
H C(CH3)2CH2SO2CH3 CF3 T-1
H C(CH3)2CH2SO2CH3 CF3 T-2
H C(CH3)2CH2SO2CH3 CF3 T-3
H C(CH3)2CH2SO2CH3 CF3 T-4
H C(CH3)2CH2SO2CH3 CF3 T-5
H C(CH3)2CH2SO2CH3 CF3 CH2OCH3
H C(CH3)2CH2SO2CH3 CF3 CH2OEt
H C(CH3)2CH2SO2CH3 CF3 CH2OPr-n
H C(CH3)2CH2SO2CH3 CF3 CH2OPr-i
H C(CH3)2CH2SO2CH3 CF3 CH2OBu-n
H C(CH3)2CH2SO2CH3 CF3 CH2OC(O)(Ph-2-Cl)
H C(CH3)2CH2SO2CH3 CF3 CH2OC(O)(Ph-3-Cl)
H C(CH3)2CH2SO2CH3 CF3 CH2OC(O)(Ph-4-Cl)
H C(CH3)2CH2SO2CH3 CF3 CH2OPh
H C(CH3)2CH2SO2CH3 CF3 CH2O(Ph-2-F)
H C(CH3)2CH2SO2CH3 CF3 CH2O(Ph-3-F)
H C(CH3)2CH2SO2CH3 CF3 CH2O(Ph-4-F)
H C(CH3)2CH2SO2CH3 CF3 CH2O(Ph-2-Cl)
H C(CH3)2CH2SO2CH3 CF3 CH2O(Ph-3-Cl)
H C(CH3)2CH2SO2CH3 CF3 CH2O(Ph-4-Cl)
H C(CH3)2CH2SO2CH3 CF3 CH2O(Ph-2-Br)
H C(CH3)2CH2SO2CH3 CF3 CH2O(Ph-3-Br)
H C(CH3)2CH2SO2CH3 CF3 CH2O(Ph-4-Br)
H C(CH3)2CH2SO2CH3 CF3 CH2O(Ph-2-CF3)
H C(CH3)2CH2SO2CH3 CF3 CH2O(Ph-3-CF3)
H C(CH3)2CH2SO2CH3 CF3 CH2O(Ph-4-CF3)
H C(CH3)2CH2SO2CH3 CF3 CH2O(Ph-2-OCF3)
H C(CH3)2CH2SO2CH3 CF3 CH2O(Ph-3-OCF3)
H C(CH3)2CH2SO2CH3 CF3 CH2O(Ph-4-OCF3)
H C(CH3)2CH2SO2CH3 CF3 CF2OPh
H C(CH3)2CH2SO2CH3 CF3 CF2O(Ph-2-F)
H C(CH3)2CH2SO2CH3 CF3 CF2O(Ph-3-F)
H C(CH3)2CH2SO2CH3 CF3 CF2O(Ph-4-F)
H C(CH3)2CH2SO2CH3 CF3 CF2O(Ph-2-Cl)
H C(CH3)2CH2SO2CH3 CF3 CF2O(Ph-3-Cl)
H C(CH3)2CH2SO2CH3 CF3 CF2O(Ph-4-Cl)
H C(CH3)2CH2SO2CH3 CF3 CF2O(Ph-2-Br)
H C(CH3)2CH2SO2CH3 CF3 CF2O(Ph-3-Br)
H C(CH3)2CH2SO2CH3 CF3 CF2O(Ph-4-Br)
H C(CH3)2CH2SO2CH3 CF3 CF2O(Ph-2-CF3)
H C(CH3)2CH2SO2CH3 CF3 CF2O(Ph-3-CF3)
H C(CH3)2CH2SO2CH3 CF3 CF2O(Ph-4-CF3)
H C(CH3)2CH2SO2CH3 CF3 CF2O(Ph-2-OCF3)
H C(CH3)2CH2SO2CH3 CF3 CF2O(Ph-3-OCF3)
H C(CH3)2CH2SO2CH3 CF3 CF2O(Ph-4-OCF3)
H C(CH3)2CH2SO2CH3 CF3 CH2S(Ph-2-Cl)
H C(CH3)2CH2SO2CH3 CF3 CH2S(Ph-3-Cl)
H C(CH3)2CH2SO2CH3 CF3 CH2S(Ph-4-Cl)
H C(CH3)2CH2SO2CH3 CF3 CH2SO2(Ph-2-Cl)
H C(CH3)2CH2SO2CH3 CF3 CH2SO2(Ph-3-Cl)
H C(CH3)2CH2SO2CH3 CF3 CH2SO2(Ph-4-Cl)
H C(CH3)2CH2SO2CH3 CF3 CH2N(CH3)2
H C(CH3)2CH2SO2CH3 CF3 CH2NH(Ph-2-Cl)
H C(CH3)2CH2SO2CH3 CF3 CH2NH(Ph-3-Cl)
H C(CH3)2CH2SO2CH3 CF3 CH2NH(Ph-4-Cl)
H C(CH3)2CH2SO2CH3 CF3 CF2C(O)OEt
H C(CH3)2CH2SO2CH3 CF3 CH2(L-5a)
H C(CH3)2CH2SO2CH3 CF3 CH2(L-14a)
H C(CH3)2CH2SO2CH3 CF3 CH2(L-24a)
H C(CH3)2CH2SO2CH3 CF3 CH2(L-36a)
H C(CH3)2CH2SO2CH3 CF3 CH2CH2Ph
H C(CH3)2CH2SO2CH3 CF3 CH2CH2(Ph-2-Cl)
H C(CH3)2CH2SO2CH3 CF3 CH2CH2(Ph-3-Cl)
H C(CH3)2CH2SO2CH3 CF3 CH2CH2(Ph-4-Cl)
H C(CH3)2CH2SO2CH3 CF3 T-22
H C(CH3)2CH2SO2CH3 CF3 T-23
H C(CH3)2CH2SO2CH3 CF3 T-24
H C(CH3)2CH2SO2CH3 CF3 C(O)OEt
H C(CH3)2CH2SO2CH3 CF3 C(O)OBu-t
H C(CH3)2CH2SO2CH3 CF3 C(O)OCH2CF3
H C(CH3)2CH2SO2CH3 CF3 CH=CH(Ph-2-F)
H C(CH3)2CH2SO2CH3 CF3 CH=CH(Ph-3-F)
H C(CH3)2CH2SO2CH3 CF3 CH=CH(Ph-4-F)
H C(CH3)2CH2SO2CH3 CF3 CH=CH(Ph-2-Cl)
H C(CH3)2CH2SO2CH3 CF3 CH=CH(Ph-3-Cl)
H C(CH3)2CH2SO2CH3 CF3 CH=CH(Ph-4-Cl)
H C(CH3)2CH2SO2CH3 CF3 CH=CH(Ph-2-Br)
H C(CH3)2CH2SO2CH3 CF3 CH=CH(Ph-3-Br)
H C(CH3)2CH2SO2CH3 CF3 CH=CH(Ph-4-Br)
H C(CH3)2CH2SO2CH3 CF3 CH=CH(Ph-2-CF3)
H C(CH3)2CH2SO2CH3 CF3 CH=CH(Ph-3-CF3)
H C(CH3)2CH2SO2CH3 CF3 CH=CH(Ph-4-CF3)
H C(CH3)2CH2SO2CH3 CF3 CH=CH(Ph-2-OCF3)
H C(CH3)2CH2SO2CH3 CF3 CH=CH(Ph-3-OCF3)
H C(CH3)2CH2SO2CH3 CF3 CH=CH(Ph-4-OCF3)
H C(CH3)2CH2SO2CH3 CF3 CH=CH(Ph-2-SCH3)
H C(CH3)2CH2SO2CH3 CF3 CH=CH(Ph-3-SCH3)
H C(CH3)2CH2SO2CH3 CF3 CH=CH(Ph-4-SCH3)
H C(CH3)2CH2SO2CH3 CF3 CH=CH(Ph-2-SO2CH3)
H C(CH3)2CH2SO2CH3 CF3 CH=CH(Ph-3-SO2CH3)
H C(CH3)2CH2SO2CH3 CF3 CH=CH(Ph-4-SO2CH3)
H C(CH3)2CH2SO2CH3 CF3 CH=CH(Ph-3,4-F2)
H C(CH3)2CH2SO2CH3 CF3 CH=CH(Ph-3-F-4-Cl)
H C(CH3)2CH2SO2CH3 CF3 CH=CH(Ph-3,4-Cl2)
H C(CH3)2CH2SO2CH3 CF3 CH=CH(Ph-3,4-Br2)
H C(CH3)2CH2SO2CH3 CF3 CH=CH(Ph-3-F-4-CF3)
H C(CH3)2CH2SO2CH3 CF3 CH=CH(Ph-3-Cl-4-OCF3)
H C(CH3)2CH2SO2CH3 CF3 CH=CH[Ph(-3-OCF2O-4-)]
H C(CH3)2CH2SO2CH3 CF3 Ph
H C(CH3)2CH2SO2CH3 CF3 Ph-2-F
H C(CH3)2CH2SO2CH3 CF3 Ph-3-F
H C(CH3)2CH2SO2CH3 CF3 Ph-4-F
H C(CH3)2CH2SO2CH3 CF3 Ph-2-Cl
H C(CH3)2CH2SO2CH3 CF3 Ph-3-Cl
H C(CH3)2CH2SO2CH3 CF3 Ph-4-Cl
H C(CH3)2CH2SO2CH3 CF3 Ph-2-Br
H C(CH3)2CH2SO2CH3 CF3 Ph-3-Br
H C(CH3)2CH2SO2CH3 CF3 Ph-4-Br
H C(CH3)2CH2SO2CH3 CF3 Ph-4-I
H C(CH3)2CH2SO2CH3 CF3 Ph-4-Bu-t
H C(CH3)2CH2SO2CH3 CF3 Ph-2-CF3
H C(CH3)2CH2SO2CH3 CF3 Ph-3-CF3
H C(CH3)2CH2SO2CH3 CF3 Ph-4-CF3
H C(CH3)2CH2SO2CH3 CF3 Ph-4-OCH3
H C(CH3)2CH2SO2CH3 CF3 Ph-4-OCHF2
H C(CH3)2CH2SO2CH3 CF3 Ph-2-OCF3
H C(CH3)2CH2SO2CH3 CF3 Ph-3-OCF3
H C(CH3)2CH2SO2CH3 CF3 Ph-4-OCF3
H C(CH3)2CH2SO2CH3 CF3 Ph-4-OCF2Br
H C(CH3)2CH2SO2CH3 CF3 Ph-4-OCH2CF3
H C(CH3)2CH2SO2CH3 CF3 Ph-4-OCF2CHF2
H C(CH3)2CH2SO2CH3 CF3 Ph-4-OCF2CHFCl
H C(CH3)2CH2SO2CH3 CF3 Ph-4-OCF2CHFBr
H C(CH3)2CH2SO2CH3 CF3 Ph-4-OCF2CF2Br
H C(CH3)2CH2SO2CH3 CF3 Ph-4-OCF2CFCl2
H C(CH3)2CH2SO2CH3 CF3 Ph-4-OCF2CCl3
H C(CH3)2CH2SO2CH3 CF3 Ph-4-OCH2CF2CHF2
H C(CH3)2CH2SO2CH3 CF3 Ph-3-OCF2CHFCF3
H C(CH3)2CH2SO2CH3 CF3 Ph-4-OCF2CHFCF3
H C(CH3)2CH2SO2CH3 CF3 Ph-4-OCH(CF3)2
H C(CH3)2CH2SO2CH3 CF3 Ph-4-OCF2CFBrCF3
H C(CH3)2CH2SO2CH3 CF3 Ph-3-OCF2CHFOCF3
H C(CH3)2CH2SO2CH3 CF3 Ph-4-OCF2CHFOCF3
H C(CH3)2CH2SO2CH3 CF3 Ph-4-OCF2CHFOCF2CF2CF3
H C(CH3)2CH2SO2CH3 CF3 Ph-4-OSO2CH3
H C(CH3)2CH2SO2CH3 CF3 Ph-4-OSO2CF3
H C(CH3)2CH2SO2CH3 CF3 Ph-3-O(Ph-4-Cl)
H C(CH3)2CH2SO2CH3 CF3 Ph-4-O(Ph-4-Cl)
H C(CH3)2CH2SO2CH3 CF3 Ph-4-O(Ph-4-Br)
H C(CH3)2CH2SO2CH3 CF3 Ph-4-O(Ph-4-CF3)
H C(CH3)2CH2SO2CH3 CF3 Ph-4-O(L-45c)Br
H C(CH3)2CH2SO2CH3 CF3 Ph-4-O(L-45c)CF3
H C(CH3)2CH2SO2CH3 CF3 Ph-3-O(L-45e)
H C(CH3)2CH2SO2CH3 CF3 Ph-4-O(L-45e)
H C(CH3)2CH2SO2CH3 CF3 Ph-4-O(L-48b)Br
H C(CH3)2CH2SO2CH3 CF3 Ph-4-SCH3
H C(CH3)2CH2SO2CH3 CF3 Ph-4-SO2CH3
H C(CH3)2CH2SO2CH3 CF3 Ph-3-S(Ph-4-Cl)
H C(CH3)2CH2SO2CH3 CF3 Ph-4-S(Ph-4-Cl)
H C(CH3)2CH2SO2CH3 CF3 Ph-4-S(Ph-4-Br)
H C(CH3)2CH2SO2CH3 CF3 Ph-4-S(Ph-4-CF3)
H C(CH3)2CH2SO2CH3 CF3 Ph-4-S(L-45c)Br
H C(CH3)2CH2SO2CH3 CF3 Ph-4-S(L-45c)CF3
H C(CH3)2CH2SO2CH3 CF3 Ph-4-S(L-45e)
H C(CH3)2CH2SO2CH3 CF3 Ph-4-S(L-48b)Br
H C(CH3)2CH2SO2CH3 CF3 Ph-4-NO2
H C(CH3)2CH2SO2CH3 CF3 Ph-4-CN
H C(CH3)2CH2SO2CH3 CF3 Ph-2,3-F2
H C(CH3)2CH2SO2CH3 CF3 Ph-2,4-F2
H C(CH3)2CH2SO2CH3 CF3 Ph-3,4-F2
H C(CH3)2CH2SO2CH3 CF3 Ph-2,5-F2
H C(CH3)2CH2SO2CH3 CF3 Ph-3,5-F2
H C(CH3)2CH2SO2CH3 CF3 Ph-2-Cl-4-F
H C(CH3)2CH2SO2CH3 CF3 Ph-2-F-3-Cl
H C(CH3)2CH2SO2CH3 CF3 Ph-3-Cl-4-F
H C(CH3)2CH2SO2CH3 CF3 Ph-2-F-4-Cl
H C(CH3)2CH2SO2CH3 CF3 Ph-3-F-4-Cl
H C(CH3)2CH2SO2CH3 CF3 Ph-2,3-Cl2
H C(CH3)2CH2SO2CH3 CF3 Ph-2,4-Cl2
H C(CH3)2CH2SO2CH3 CF3 Ph-2,5-Cl2
H C(CH3)2CH2SO2CH3 CF3 Ph-3,4-Cl2
H C(CH3)2CH2SO2CH3 CF3 Ph-3,5-Cl2
H C(CH3)2CH2SO2CH3 CF3 Ph-3-Br-4-F
H C(CH3)2CH2SO2CH3 CF3 Ph-2-F-4-Br
H C(CH3)2CH2SO2CH3 CF3 Ph-2-F-5-Br
H C(CH3)2CH2SO2CH3 CF3 Ph-3,4-Br2
H C(CH3)2CH2SO2CH3 CF3 Ph-3,5-Br2
H C(CH3)2CH2SO2CH3 CF3 Ph-3-CH3-4-F
H C(CH3)2CH2SO2CH3 CF3 Ph-3-F-4-CH3
H C(CH3)2CH2SO2CH3 CF3 Ph-2-F-5-CH3
H C(CH3)2CH2SO2CH3 CF3 Ph-2,4-(CH3)2
H C(CH3)2CH2SO2CH3 CF3 Ph-3,4-(CH3)2
H C(CH3)2CH2SO2CH3 CF3 Ph-2-F-3-CF3
H C(CH3)2CH2SO2CH3 CF3 Ph-3-CF3-4-F
H C(CH3)2CH2SO2CH3 CF3 Ph-3-CF3-4-Cl
H C(CH3)2CH2SO2CH3 CF3 Ph-2-F-4-CF3
H C(CH3)2CH2SO2CH3 CF3 Ph-3-F-4-CF3
H C(CH3)2CH2SO2CH3 CF3 Ph-2-F-5-CF3
H C(CH3)2CH2SO2CH3 CF3 Ph-3-F-5-CF3
H C(CH3)2CH2SO2CH3 CF3 Ph-2-Cl-4-CF3
H C(CH3)2CH2SO2CH3 CF3 Ph-3,5-(CF3)2
H C(CH3)2CH2SO2CH3 CF3 Ph-3-Br-4-OCH3
H C(CH3)2CH2SO2CH3 CF3 Ph-3-F-4-OCHF2
H C(CH3)2CH2SO2CH3 CF3 Ph-3-Cl-4-OCHF2
H C(CH3)2CH2SO2CH3 CF3 Ph-3-Br-4-OCHF2
H C(CH3)2CH2SO2CH3 CF3 Ph-3-F-4-OCF3
H C(CH3)2CH2SO2CH3 CF3 Ph-3-Cl-4-OCF3
H C(CH3)2CH2SO2CH3 CF3 Ph-3-Br-4-OCF3
H C(CH3)2CH2SO2CH3 CF3 Ph-3-F-4-OCF2Br
H C(CH3)2CH2SO2CH3 CF3 Ph-3-Cl-4-OCF2Br
H C(CH3)2CH2SO2CH3 CF3 Ph-3-Br-4-OCF2Br
H C(CH3)2CH2SO2CH3 CF3 Ph-3-F-4-OCF2CHF2
H C(CH3)2CH2SO2CH3 CF3 Ph-3-Cl-4-OCF2CHF2
H C(CH3)2CH2SO2CH3 CF3 Ph-3-Br-4-OCF2CHF2
H C(CH3)2CH2SO2CH3 CF3 Ph-3-F-4-OCF2CHFCl
H C(CH3)2CH2SO2CH3 CF3 Ph-3-Cl-4-OCF2CHFCl
H C(CH3)2CH2SO2CH3 CF3 Ph-3-Br-4-OCF2CHFCl
H C(CH3)2CH2SO2CH3 CF3 Ph-3-F-4-OCF2CHFCF3
H C(CH3)2CH2SO2CH3 CF3 Ph-3-Cl-4-OCF2CHFCF3
H C(CH3)2CH2SO2CH3 CF3 Ph-3-Br-4-OCF2CHFCF3
H C(CH3)2CH2SO2CH3 CF3 Ph-3-F-4-OCF2CHFOCF3
H C(CH3)2CH2SO2CH3 CF3 Ph-3-Cl-4-OCF2CHFOCF3
H C(CH3)2CH2SO2CH3 CF3 Ph-3-Br-4-OCF2CHFOCF3
H C(CH3)2CH2SO2CH3 CF3 Ph-3-CH3-4-OCF2CHFOCF3
H C(CH3)2CH2SO2CH3 CF3 Ph-3-F-4-OCF2CHFOCF2CF2CF3
H C(CH3)2CH2SO2CH3 CF3 Ph-3-Cl-4-OCF2CHFOCF2CF2CF3
H C(CH3)2CH2SO2CH3 CF3 Ph-3-Br-4-OCF2CHFOCF2CF2CF3
H C(CH3)2CH2SO2CH3 CF3 Ph(-3-OCF2O-4-)
H C(CH3)2CH2SO2CH3 CF3 Ph(-3-OCF2CF2O-4-)
H C(CH3)2CH2SO2CH3 CF3 Ph-3-OPh-4-F
H C(CH3)2CH2SO2CH3 CF3 Ph-3-NO2-4-F
H C(CH3)2CH2SO2CH3 CF3 Ph-3-NO2-4-Cl
H C(CH3)2CH2SO2CH3 CF3 Ph-2-F-5-NO2
H C(CH3)2CH2SO2CH3 CF3 Ph-3-CN-4-F
H C(CH3)2CH2SO2CH3 CF3 Ph-2,3,4-F3
H C(CH3)2CH2SO2CH3 CF3 Ph-2,3,5-F3
H C(CH3)2CH2SO2CH3 CF3 Ph-2,4,5-F3
H C(CH3)2CH2SO2CH3 CF3 Ph-3,4,5-F3
H C(CH3)2CH2SO2CH3 CF3 Ph-2,3-F2-4-CH3
H C(CH3)2CH2SO2CH3 CF3 Ph-2,3-F2-4-CF3
H C(CH3)2CH2SO2CH3 CF3 Ph-3,4-F2-5-CF3
H C(CH3)2CH2SO2CH3 CF3 Ph-2-F-3-Cl-5-CF3
H C(CH3)2CH2SO2CH3 CF3 Ph-3,5-Cl2-4-OCH3
H C(CH3)2CH2SO2CH3 CF3 1-Naph
H C(CH3)2CH2SO2CH3 CF3 2-Naph
H C(CH3)2CH2SO2CH3 CF3 (L-1b)Br
H C(CH3)2CH2SO2CH3 CF3 (L-1c)Cl
H C(CH3)2CH2SO2CH3 CF3 (L-1c)Br
H C(CH3)2CH2SO2CH3 CF3 (L-1c)I
H C(CH3)2CH2SO2CH3 CF3 (L-1c)CF3
H C(CH3)2CH2SO2CH3 CF3 (L-2b)Br
H C(CH3)2CH2SO2CH3 CF3 (L-3b)Cl
H C(CH3)2CH2SO2CH3 CF3 (L-3b)Br
H C(CH3)2CH2SO2CH3 CF3 (L-3c)F
H C(CH3)2CH2SO2CH3 CF3 (L-3c)Cl
H C(CH3)2CH2SO2CH3 CF3 (L-3c)Br
H C(CH3)2CH2SO2CH3 CF3 (L-3c)I
H C(CH3)2CH2SO2CH3 CF3 (L-3c)CF3
H C(CH3)2CH2SO2CH3 CF3 (L-3c)CN
H C(CH3)2CH2SO2CH3 CF3 L-3d
H C(CH3)2CH2SO2CH3 CF3 (L-4b)Cl
H C(CH3)2CH2SO2CH3 CF3 (L-4b)Br
H C(CH3)2CH2SO2CH3 CF3 (L-4b)CN
H C(CH3)2CH2SO2CH3 CF3 (L-10b)Cl
H C(CH3)2CH2SO2CH3 CF3 (L-10b)Br
H C(CH3)2CH2SO2CH3 CF3 (L-15b)CF3
H C(CH3)2CH2SO2CH3 CF3 (L-16a)CHF2
H C(CH3)2CH2SO2CH3 CF3 (L-16a)CF2Br
H C(CH3)2CH2SO2CH3 CF3 (L-17a)Cl
H C(CH3)2CH2SO2CH3 CF3 (L-21b)Cl
H C(CH3)2CH2SO2CH3 CF3 (L-21b)Br
H C(CH3)2CH2SO2CH3 CF3 (L-21b)I
H C(CH3)2CH2SO2CH3 CF3 (L-21b)CF3
H C(CH3)2CH2SO2CH3 CF3 (L-22b)Cl
H C(CH3)2CH2SO2CH3 CF3 (L-22b)Br
H C(CH3)2CH2SO2CH3 CF3 (L-23b)Cl
H C(CH3)2CH2SO2CH3 CF3 (L-23b)Br
H C(CH3)2CH2SO2CH3 CF3 (L-23c)Cl
H C(CH3)2CH2SO2CH3 CF3 (L-23c)Br
H C(CH3)2CH2SO2CH3 CF3 (L-31a)Cl
H C(CH3)2CH2SO2CH3 CF3 (L-31a)Br
H C(CH3)2CH2SO2CH3 CF3 (L-45c)F
H C(CH3)2CH2SO2CH3 CF3 (L-45c)Cl
H C(CH3)2CH2SO2CH3 CF3 (L-45c)Br
H C(CH3)2CH2SO2CH3 CF3 (L-45c)I
H C(CH3)2CH2SO2CH3 CF3 (L-45c)CF3
H C(CH3)2CH2SO2CH3 CF3 L-45e
H C(CH3)2CH2SO2CH3 CF3 L-45f
H C(CH3)2CH2SO2CH3 CF3 (L-46c)F
H C(CH3)2CH2SO2CH3 CF3 (L-46c)Cl
H C(CH3)2CH2SO2CH3 CF3 (L-46c)Br
H C(CH3)2CH2SO2CH3 CF3 (L-46c)I
H C(CH3)2CH2SO2CH3 CF3 (L-46c)CF3
H C(CH3)2CH2SO2CH3 CF3 (L-46c)OCH2CF3
H C(CH3)2CH2SO2CH3 CF3 (L-46c)OCH(CF3)2
H C(CH3)2CH2SO2CH3 CF3 L-46d
H C(CH3)2CH2SO2CH3 CF3 L-47a
H C(CH3)2CH2SO2CH3 CF3 L-47d
H C(CH3)2CH2SO2CH3 CF3 (L-48b)Br
H C(CH3)2CH2SO2CH3 CF3 (L-50b)Cl
H C(CH3)2CH2SO2CH3 CF3 (L-50b)Br
H C(CH3)2CH2SO2CH3 CF3 (L-51b)Cl
H C(CH3)2CH2SO2CH3 CF2Cl Ph-4-Cl
H C(CH3)2CH2SO2CH3 CF2Cl Ph-4-Br
H C(CH3)2CH2SO2CH3 CF2Cl Ph-4-CF3
H C(CH3)2CH2SO2CH3 CF2Cl Ph-4-OCF3
H C(CH3)2CH2SO2CH3 CF2Cl Ph-4-OCF2Br
H C(CH3)2CH2SO2CH3 CF2Cl Ph-4-OCF2CHFCF3
H C(CH3)2CH2SO2CH3 CF2Cl Ph-4-OCF2CHFOCF3
H C(CH3)2CH2SO2CH3 CF2Cl Ph-4-OCF2CHFOCF2CF2CF3
H C(CH3)2CH2SO2CH3 CF2Cl Ph-4-O(L-45g)
H C(CH3)2CH2SO2CH3 CF2Cl Ph-3,4-Cl2
H C(CH3)2CH2SO2CH3 CF2Cl Ph(-3-OCF2O-4-)
H C(CH3)2CH2SO2CH3 CF2Cl Ph(-3-OCF2CF2O-4-)
H C(CH3)2CH2SO2CH3 CF2Cl (L-45c)CF3
H C(CH3)2CH2SO2CH3 CF2Cl L-45f
H C(CH3)2CH2SO2CH3 CF2Cl (L-46c)CF3
H C(CH3)2CH2SO2CH3 CF2Cl L-46d
H C(CH3)2CH2SO2CH3 CFCl2 Ph-4-Br
H C(CH3)2CH2SO2CH3 CF2Br Ph-4-Cl
H C(CH3)2CH2SO2CH3 CF2Br Ph-4-Br
H C(CH3)2CH2SO2CH3 CF2Br Ph-4-CF3
H C(CH3)2CH2SO2CH3 CF2Br Ph-4-OCF3
H C(CH3)2CH2SO2CH3 CF2Br Ph-4-OCF2Br
H C(CH3)2CH2SO2CH3 CF2Br Ph-4-OCF2CHFCF3
H C(CH3)2CH2SO2CH3 CF2Br Ph-4-OCF2CHFOCF3
H C(CH3)2CH2SO2CH3 CF2Br Ph-4-OCF2CHFOCF2CF2CF3
H C(CH3)2CH2SO2CH3 CF2Br Ph-4-O(L-45g)
H C(CH3)2CH2SO2CH3 CF2Br Ph-3,4-Cl2
H C(CH3)2CH2SO2CH3 CF2Br Ph(-3-OCF2O-4-)
H C(CH3)2CH2SO2CH3 CF2Br Ph(-3-OCF2CF2O-4-)
H C(CH3)2CH2SO2CH3 CF2Br (L-45c)CF3
H C(CH3)2CH2SO2CH3 CF2Br L-45f
H C(CH3)2CH2SO2CH3 CF2Br (L-46c)CF3
H C(CH3)2CH2SO2CH3 CF2Br L-46d
H C(CH3)2CH2SO2CH3 CFClBr Ph-4-CF3
H C(CH3)2CH2SO2CH3 CFBr2 Ph-4-OCF3
H C(CH3)2CH2SO2CH3 CF2CHF2 (L-45c)CF3
H C(CH3)2CH2SO2CH3 CF2CF3 Ph-4-Cl
H C(CH3)2CH2SO2CH3 CF2CF3 Ph-4-Br
H C(CH3)2CH2SO2CH3 CF2CF3 Ph-4-CF3
H C(CH3)2CH2SO2CH3 CF2CF3 Ph-4-OCF3
H C(CH3)2CH2SO2CH3 CF2CF3 Ph-4-OCF2Br
H C(CH3)2CH2SO2CH3 CF2CF3 Ph-4-OCF2CHFCF3
H C(CH3)2CH2SO2CH3 CF2CF3 Ph-4-OCF2CHFOCF3
H C(CH3)2CH2SO2CH3 CF2CF3 Ph-4-OCF2CHFOCF2CF2CF3
H C(CH3)2CH2SO2CH3 CF2CF3 Ph-4-O(L-45g)
H C(CH3)2CH2SO2CH3 CF2CF3 Ph-3,4-Cl2
H C(CH3)2CH2SO2CH3 CF2CF3 Ph(-3-OCF2O-4-)
H C(CH3)2CH2SO2CH3 CF2CF3 Ph(-3-OCF2CF2O-4-)
H C(CH3)2CH2SO2CH3 CF2CF3 (L-45c)CF3
H C(CH3)2CH2SO2CH3 CF2CF3 L-45f
H C(CH3)2CH2SO2CH3 CF2CF3 (L-46c)CF3
H C(CH3)2CH2SO2CH3 CF2CF3 L-46d
H C(CH3)2CH2SO2CH3 CF2CF2Cl Ph-4-Br
H C(CH3)2CH2SO2CH3 CFClCF3 Ph-4-CF3
H C(CH3)2CH2SO2CH3 CFClCF2Cl Ph-4-OCF3
H C(CH3)2CH2SO2CH3 CF2CF2Br (L-45c)CF3
H C(CH3)2CH2SO2CH3 CFBrCF3 Ph-4-Br
H C(CH3)2CH2SO2CH3 CF2CHFCF3 Ph-4-CF3
H C(CH3)2CH2SO2CH3 CF2CF2CF3 Ph-4-Cl
H C(CH3)2CH2SO2CH3 CF2CF2CF3 Ph-4-Br
H C(CH3)2CH2SO2CH3 CF2CF2CF3 Ph-4-CF3
H C(CH3)2CH2SO2CH3 CF2CF2CF3 Ph-4-OCF3
H C(CH3)2CH2SO2CH3 CF2CF2CF3 Ph-4-OCF2Br
H C(CH3)2CH2SO2CH3 CF2CF2CF3 Ph-4-OCF2CHFCF3
H C(CH3)2CH2SO2CH3 CF2CF2CF3 Ph-4-OCF2CHFOCF3
H C(CH3)2CH2SO2CH3 CF2CF2CF3 Ph-4-OCF2CHFOCF2CF2CF3
H C(CH3)2CH2SO2CH3 CF2CF2CF3 Ph-4-O(L-45g)
H C(CH3)2CH2SO2CH3 CF2CF2CF3 Ph-3,4-Cl2
H C(CH3)2CH2SO2CH3 CF2CF2CF3 Ph(-3-OCF2O-4-)
H C(CH3)2CH2SO2CH3 CF2CF2CF3 Ph(-3-OCF2CF2O-4-)
H C(CH3)2CH2SO2CH3 CF2CF2CF3 (L-45c)CF3
H C(CH3)2CH2SO2CH3 CF2CF2CF3 L-45f
H C(CH3)2CH2SO2CH3 CF2CF2CF3 (L-46c)CF3
H C(CH3)2CH2SO2CH3 CF2CF2CF3 L-46d
H C(CH3)2CH2SO2CH3 CF(CF3)2 Ph-4-OCF3
H C(CH3)2CH2SO2CH3 CF2CF2CF2CF3 (L-45c)CF3
H C(CH3)2CH2SO2CH3 T-1 Ph-4-Br
H C(CH3)2CH2SO2CH3 T-2 Ph-4-CF3
H C(CH3)2CH2SO2CH3 CH2OCH3 Ph-4-OCF3
H C(CH3)2CH2SO2CH3 CH2OEt (L-45c)CF3
H C(CH3)2CH2SO2CH3 CH2OCH2CF3 Ph-4-Br
H C(CH3)2CH2SO2CH3 CH2OCH(CF3)2 Ph-4-CF3
H C(CH3)2CH2SO2CH3 CF2OCH3 Ph-4-Cl
H C(CH3)2CH2SO2CH3 CF2OCH3 Ph-4-Br
H C(CH3)2CH2SO2CH3 CF2OCH3 Ph-4-CF3
H C(CH3)2CH2SO2CH3 CF2OCH3 Ph-4-OCF3
H C(CH3)2CH2SO2CH3 CF2OCH3 Ph-4-OCF2Br
H C(CH3)2CH2SO2CH3 CF2OCH3 Ph-4-OCF2CHFCF3
H C(CH3)2CH2SO2CH3 CF2OCH3 Ph-4-OCF2CHFOCF3
H C(CH3)2CH2SO2CH3 CF2OCH3 Ph-4-OCF2CHFOCF2CF2CF3
H C(CH3)2CH2SO2CH3 CF2OCH3 Ph-4-O(L-45g)
H C(CH3)2CH2SO2CH3 CF2OCH3 Ph-3,4-Cl2
H C(CH3)2CH2SO2CH3 CF2OCH3 Ph(-3-OCF2O-4-)
H C(CH3)2CH2SO2CH3 CF2OCH3 Ph(-3-OCF2CF2O-4-)
H C(CH3)2CH2SO2CH3 CF2OCH3 (L-45c)CF3
H C(CH3)2CH2SO2CH3 CF2OCH3 L-45f
H C(CH3)2CH2SO2CH3 CF2OCH3 (L-46c)CF3
H C(CH3)2CH2SO2CH3 CF2OCH3 L-46d
H C(CH3)2CH2SO2CH3 CH2SCH3 Ph-4-OCF3
H C(CH3)2CH2SO2CH3 CH2SO2CH3 (L-45c)CF3
H C(CH3)2CH2SO2CH3 CH2SCF3 Ph-4-Br
H C(CH3)2CH2SO2CH3 CF2SCH3 Ph-4-Cl
H C(CH3)2CH2SO2CH3 CF2SCH3 Ph-4-Br
H C(CH3)2CH2SO2CH3 CF2SCH3 Ph-4-CF3
H C(CH3)2CH2SO2CH3 CF2SCH3 Ph-4-OCF3
H C(CH3)2CH2SO2CH3 CF2SCH3 Ph-4-OCF2Br
H C(CH3)2CH2SO2CH3 CF2SCH3 Ph-4-OCF2CHFCF3
H C(CH3)2CH2SO2CH3 CF2SCH3 Ph-4-OCF2CHFOCF3
H C(CH3)2CH2SO2CH3 CF2SCH3 Ph-4-OCF2CHFOCF2CF2CF3
H C(CH3)2CH2SO2CH3 CF2SCH3 Ph-4-O(L-45g)
H C(CH3)2CH2SO2CH3 CF2SCH3 Ph-3,4-Cl2
H C(CH3)2CH2SO2CH3 CF2SCH3 Ph(-3-OCF2O-4-)
H C(CH3)2CH2SO2CH3 CF2SCH3 Ph(-3-OCF2CF2O-4-)
H C(CH3)2CH2SO2CH3 CF2SCH3 (L-45c)CF3
H C(CH3)2CH2SO2CH3 CF2SCH3 L-45f
H C(CH3)2CH2SO2CH3 CF2SCH3 (L-46c)CF3
H C(CH3)2CH2SO2CH3 CF2SCH3 L-46d
H C(CH3)2CH2SO2CH3 CF2SEt Ph-4-CF3
H C(CH3)2CH2SO2CH3 CF2SPr-n Ph-4-OCF3
H C(CH3)2CH2SO2CH3 CF2SPr-i (L-45c)CF3
H C(CH3)2CH2SO2CH3 CF2SCH2Ph Ph-4-Br
H C(CH3)2CH2SO2CH3 CF2SPh Ph-4-CF3
H C(CH3)2CH2SO2CH3 CF2C(O)OEt Ph-4-OCF3
H C(CH3)2CH2SO2CH3 CF2SO2N(CH3)2 (L-45c)CF3
H C(CH3)2CH2SO2CH3 C(O)OEt Ph-4-Br
H C(CH3)2CH2SO2CH3 C(O)SEt Ph-4-CF3
H C(CH3)2CH2SEt CF3 CH=CH(Ph-4-Cl)
H C(CH3)2CH2SEt CF3 Ph-4-Cl
H C(CH3)2CH2SEt CF3 Ph-4-Br
H C(CH3)2CH2SEt CF3 Ph-4-CF3
H C(CH3)2CH2SEt CF3 Ph-4-OCF3
H C(CH3)2CH2SEt CF3 Ph-4-OCF2Br
H C(CH3)2CH2SEt CF3 Ph-4-OCF2CHFCF3
H C(CH3)2CH2SEt CF3 Ph-4-OCF2CHFOCF3
H C(CH3)2CH2SEt CF3 Ph-4-OCF2CHFOCF2CF2CF3
H C(CH3)2CH2SEt CF3 Ph-4-O(L-45g)
H C(CH3)2CH2SEt CF3 Ph-3,4-Cl2
H C(CH3)2CH2SEt CF3 Ph(-3-OCF2O-4-)
H C(CH3)2CH2SEt CF3 Ph(-3-OCF2CF2O-4-)
H C(CH3)2CH2SEt CF3 (L-45c)CF3
H C(CH3)2CH2SEt CF3 L-45f
H C(CH3)2CH2SEt CF3 (L-46c)CF3
H C(CH3)2CH2SEt CF3 L-46d
H C(CH3)2CH2S(O)Et CF3 CH=CH(Ph-4-Cl)
H C(CH3)2CH2S(O)Et CF3 Ph-4-Cl
H C(CH3)2CH2S(O)Et CF3 Ph-4-Br
H C(CH3)2CH2S(O)Et CF3 Ph-4-CF3
H C(CH3)2CH2S(O)Et CF3 Ph-4-OCF3
H C(CH3)2CH2S(O)Et CF3 Ph-4-OCF2Br
H C(CH3)2CH2S(O)Et CF3 Ph-4-OCF2CHFCF3
H C(CH3)2CH2S(O)Et CF3 Ph-4-OCF2CHFOCF3
H C(CH3)2CH2S(O)Et CF3 Ph-4-OCF2CHFOCF2CF2CF3
H C(CH3)2CH2S(O)Et CF3 Ph-4-O(L-45g)
H C(CH3)2CH2S(O)Et CF3 Ph-3,4-Cl2
H C(CH3)2CH2S(O)Et CF3 Ph(-3-OCF2O-4-)
H C(CH3)2CH2S(O)Et CF3 Ph(-3-OCF2CF2O-4-)
H C(CH3)2CH2S(O)Et CF3 (L-45c)CF3
H C(CH3)2CH2S(O)Et CF3 L-45f
H C(CH3)2CH2S(O)Et CF3 (L-46c)CF3
H C(CH3)2CH2S(O)Et CF3 L-46d
H C(CH3)2CH2SO2Et CF3 CH=CH(Ph-4-Cl)
H C(CH3)2CH2SO2Et CF3 Ph-4-Cl
H C(CH3)2CH2SO2Et CF3 Ph-4-Br
H C(CH3)2CH2SO2Et CF3 Ph-4-CF3
H C(CH3)2CH2SO2Et CF3 Ph-4-OCF3
H C(CH3)2CH2SO2Et CF3 Ph-4-OCF2Br
H C(CH3)2CH2SO2Et CF3 Ph-4-OCF2CHFCF3
H C(CH3)2CH2SO2Et CF3 Ph-4-OCF2CHFOCF3
H C(CH3)2CH2SO2Et CF3 Ph-4-OCF2CHFOCF2CF2CF3
H C(CH3)2CH2SO2Et CF3 Ph-4-O(L-45g)
H C(CH3)2CH2SO2Et CF3 Ph-3,4-Cl2
H C(CH3)2CH2SO2Et CF3 Ph(-3-OCF2O-4-)
H C(CH3)2CH2SO2Et CF3 Ph(-3-OCF2CF2O-4-)
H C(CH3)2CH2SO2Et CF3 (L-45c)CF3
H C(CH3)2CH2SO2Et CF3 L-45f
H C(CH3)2CH2SO2Et CF3 (L-46c)CF3
H C(CH3)2CH2SO2Et CF3 L-46d
H C(CH3)2CH2SPr-n CF3 Ph-4-Br
H C(CH3)2CH2SPr-n CF3 Ph-4-CF3
H C(CH3)2CH2SPr-n CF3 Ph-4-OCF3
H C(CH3)2CH2SPr-n CF3 (L-45c)CF3
H C(CH3)2CH2S(O)Pr-n CF3 Ph-4-OCF3
H C(CH3)2CH2SO2Pr-n CF3 Ph-4-Br
H C(CH3)2CH2SO2Pr-n CF3 Ph-4-CF3
H C(CH3)2CH2SO2Pr-n CF3 Ph-4-OCF3
H C(CH3)2CH2SO2Pr-n CF3 (L-45c)CF3
H C(CH3)2CH2SPr-i CF3 Ph-4-Br
H C(CH3)2CH2SPr-i CF3 Ph-4-CF3
H C(CH3)2CH2SPr-i CF3 Ph-4-OCF3
H C(CH3)2CH2SPr-i CF3 (L-45c)CF3
H C(CH3)2CH2S(O)Pr-i CF3 (L-45c)CF3
H C(CH3)2CH2SO2Pr-i CF3 Ph-4-Br
H C(CH3)2CH2SBu-t CF3 Ph-4-CF3
H C(CH3)2CH2S(O)Bu-t CF3 Ph-4-OCF3
H C(CH3)2CH2SCH2(Ph-4-Cl) CF3 (L-45c)CF3
H C(CH3)2CH2SO2NH2 CF3 Ph-4-Br
H C(CH3)2CH2SO2NHCH3 CF3 Ph-4-CF3
H C(CH3)2CH2SO2NHEt CF3 Ph-4-Br
H C(CH3)2CH2SO2NHEt CF3 Ph-4-CF3
H C(CH3)2CH2SO2NHEt CF3 Ph-4-OCF3
H C(CH3)2CH2SO2NHEt CF3 (L-45c)CF3
H C(CH3)2CH2SO2NHCH2CH2OCH3 CF3 Ph-4-OCF3
H C(CH3)2CH2SO2NHCH2CH2OC(O)CH3 CF3 (L-45c)CF3
H C(CH3)2CH2SO2NHCH2CH2SCH3 CF3 Ph-4-Br
H C(CH3)2CH2SO2NHCH2CH2S(O)CH3 CF3 Ph-4-CF3
H C(CH3)2CH2SO2NHCH2CH2SO2CH3 CF3 Ph-4-OCF3
H C(CH3)2CH2SO2NHCH2CH2SEt CF3 (L-45c)CF3
H C(CH3)2CH2SO2NHCH2CH2S(O)Et CF3 Ph-4-Br
H C(CH3)2CH2SO2NHCH2CH2SO2Et CF3 Ph-4-CF3
H C(CH3)2CH2SO2NHCH2CH2SPh CF3 Ph-4-OCF3
H C(CH3)2CH2SO2NHCH2CH2S(O)Ph CF3 (L-45c)CF3
H C(CH3)2CH2SO2NHCH2CH2SO2Ph CF3 Ph-4-Br
H C(CH3)2CH2SO2NHCH2Ph CF3 Ph-4-CF3
H C(CH3)2CH2SO2N(CH3)2 CF3 Ph-4-Br
H C(CH3)2CH2SO2N(CH3)2 CF3 Ph-4-CF3
H C(CH3)2CH2SO2N(CH3)2 CF3 Ph-4-OCF3
H C(CH3)2CH2SO2N(CH3)2 CF3 (L-45c)CF3
H C(CH3)2CH2SO2N(Et)2 CF3 CF2O(Ph-4-Cl)
H C(CH3)2CH2SO2N(Et)2 CF3 CH=CH(Ph-4-Cl)
H C(CH3)2CH2SO2N(Et)2 CF3 CH=CH(Ph-4-Br)
H C(CH3)2CH2SO2N(Et)2 CF3 CH=CH(Ph-4-CF3)
H C(CH3)2CH2SO2N(Et)2 CF3 CH=CH(Ph-4-OCF3)
H C(CH3)2CH2SO2N(Et)2 CF3 CH=CH(Ph-3,4-Cl2)
H C(CH3)2CH2SO2N(Et)2 CF3 Ph-4-F
H C(CH3)2CH2SO2N(Et)2 CF3 Ph-4-Cl
H C(CH3)2CH2SO2N(Et)2 CF3 Ph-4-Br
H C(CH3)2CH2SO2N(Et)2 CF3 Ph-4-CF3
H C(CH3)2CH2SO2N(Et)2 CF3 Ph-4-OCF3
H C(CH3)2CH2SO2N(Et)2 CF3 Ph-4-OCF2Br
H C(CH3)2CH2SO2N(Et)2 CF3 Ph-4-OCF2CHF2
H C(CH3)2CH2SO2N(Et)2 CF3 Ph-4-OCF2CHFCF3
H C(CH3)2CH2SO2N(Et)2 CF3 Ph-4-OCF2CHFOCF3
H C(CH3)2CH2SO2N(Et)2 CF3 Ph-4-OCF2CHFOCF2CF2CF3
H C(CH3)2CH2SO2N(Et)2 CF3 Ph-4-O(L-45g)
H C(CH3)2CH2SO2N(Et)2 CF3 Ph-3,4-F2
H C(CH3)2CH2SO2N(Et)2 CF3 Ph-3-F-4-Cl
H C(CH3)2CH2SO2N(Et)2 CF3 Ph-3,4-Cl2
H C(CH3)2CH2SO2N(Et)2 CF3 Ph(-3-OCF2O-4-)
H C(CH3)2CH2SO2N(Et)2 CF3 Ph(-3-OCF2CF2O-4-)
H C(CH3)2CH2SO2N(Et)2 CF3 (L-45c)CF3
H C(CH3)2CH2SO2N(Et)2 CF3 L-45f
H C(CH3)2CH2SO2N(Et)2 CF3 (L-46c)CF3
H C(CH3)2CH2SO2N(Et)2 CF3 L-46d
H C(CH3)2CH2SO2(T-19) CF3 Ph-4-OCF3
H C(CH3)2CH2SO2(T-21) CF3 (L-46c)CF3
H C(CH3)2CH2SPh CF3 Ph-4-Br
H C(CH3)2CH2S(O)Ph CF3 Ph-4-CF3
H C(CH3)2CH2SO2Ph CF3 Ph-4-OCF3
H C(CH3)2CH2S(L-45a) CF3 (L-45c)CF3
H C(CH3)2CH2S(O)(L-45a) CF3 Ph-4-Br
H C(CH3)2CH2SO2(L-45a) CF3 Ph-4-CF3
H CH2CH2CH2SCH3 CF3 Ph-4-OCF3
H CH(CH3)CH2CH2SCH3 CF3 Ph-4-Br
H CH(CH3)CH2CH2SCH3 CF3 Ph-4-CF3
H CH(CH3)CH2CH2SCH3 CF3 Ph-4-OCF3
H CH(CH3)CH2CH2SCH3 CF3 (L-45c)CF3
H CH(CH3)CH2CH2S(O)CH3 CF3 Ph-4-Br
H CH(CH3)CH2CH2S(O)CH3 CF3 Ph-4-CF3
H CH(CH3)CH2CH2S(O)CH3 CF3 Ph-4-OCF3
H CH(CH3)CH2CH2S(O)CH3 CF3 (L-45c)CF3
H CH(CH3)CH2CH2SO2CH3 CF3 Ph-4-Br
H CH(CH3)CH2CH2SO2CH3 CF3 Ph-4-CF3
H CH(CH3)CH2CH2SO2CH3 CF3 Ph-4-OCF3
H CH(CH3)CH2CH2SO2CH3 CF3 (L-45c)CF3
H CH(CH3)CH2CH2SEt CF3 Ph-4-Br
H CH(CH3)CH2CH2SEt CF3 Ph-4-CF3
H CH(CH3)CH2CH2SEt CF3 Ph-4-OCF3
H CH(CH3)CH2CH2SEt CF3 (L-45c)CF3
H CH(CH3)CH2CH2S(O)Et CF3 Ph-4-Br
H CH(CH3)CH2CH2S(O)Et CF3 Ph-4-CF3
H CH(CH3)CH2CH2S(O)Et CF3 Ph-4-OCF3
H CH(CH3)CH2CH2S(O)Et CF3 (L-45c)CF3
H CH(CH3)CH2CH2SO2Et CF3 Ph-4-Br
H CH(CH3)CH2CH2SO2Et CF3 Ph-4-CF3
H CH(CH3)CH2CH2SO2Et CF3 Ph-4-OCF3
H CH(CH3)CH2CH2SO2Et CF3 (L-45c)CF3
H CH(Et)CH2CH2SCH3 CF3 (L-45c)CF3
H CH(CH2OH)CH2CH2SCH3 CF3 Ph-4-Br
H C(CH3)2CH2CH2SCH3 CF3 Ph-4-CF3
H C(CH3)2CH2CH2SEt CF3 Ph-4-OCF3
H CH(CH3)(CH2)3SCH3 CF3 Ph-4-Br
H CH(CH3)(CH2)3SCH3 CF3 Ph-4-CF3
H CH(CH3)(CH2)3SCH3 CF3 Ph-4-OCF3
H CH(CH3)(CH2)3SCH3 CF3 (L-45c)CF3
H CH(CH3)(CH2)3S(O)CH3 CF3 (L-45c)CF3
H CH(CH3)(CH2)3SO2CH3 CF3 Ph-4-Br
H CH(CH3)(CH2)3SO2CH3 CF3 Ph-4-CF3
H CH(CH3)(CH2)3SO2CH3 CF3 Ph-4-OCF3
H CH(CH3)(CH2)3SO2CH3 CF3 (L-45c)CF3
H CH(CH3)(CH2)3SEt CF3 Ph-4-Br
H CH(CH3)(CH2)3SEt CF3 Ph-4-CF3
H CH(CH3)(CH2)3SEt CF3 Ph-4-OCF3
H CH(CH3)(CH2)3SEt CF3 (L-45c)CF3
H CH(CH3)(CH2)3S(O)Et CF3 Ph-4-Br
H CH(CH3)(CH2)3SO2Et CF3 Ph-4-Br
H CH(CH3)(CH2)3SO2Et CF3 Ph-4-CF3
H CH(CH3)(CH2)3SO2Et CF3 Ph-4-OCF3
H CH(CH3)(CH2)3SO2Et CF3 (L-45c)CF3
H C(CH3)2(CH2)3SCH3 CF3 Ph-4-CF3
H C(CH3)2(CH2)3S(O)CH3 CF3 Ph-4-OCF3
H CH(CH3)CH2SO2CH3 CF3 (L-45c)CF3
H C(CH3)2(CH2)3SEt CF3 Ph-4-Br
H C(CH3)2(CH2)3S(O)Et CF3 Ph-4-CF3
H C(CH3)2(CH2)3SO2Et CF3 Ph-4-OCF3
H C(CH3)2(CH2)3SO2NHCH3 CF3 (L-45c)CF3
H C(CH3)2(CH2)3SO2NHEt CF3 Ph-4-Br
H C(CH3)2(CH2)3SO2N(CH3)2 CF3 Ph-4-CF3
H C(CH3)2(CH2)3SO2N(Et)2 CF3 Ph-4-OCF3
H C(CH3)2CH2CH2CH(CH3)SCH3 CF3 (L-45c)CF3
H CH(CH3)(CH2)4SCH3 CF3 Ph-4-Br
H CH(CH3)(CH2)4SO2CH3 CF3 Ph-4-CF3
H CH(CH3)(CH2)4SEt CF3 Ph-4-OCF3
H CH(CH3)(CH2)4S(O)Et CF3 (L-45c)CF3
H CH(CH3)(CH2)4SO2Et CF3 Ph-4-Br
H T-6 CF3 Ph-4-CF3
H T-7 CF3 Ph-4-OCF3
H T-8 CF3 (L-45c)CF3
H T-9 CF3 Ph-4-Br
H T-11 CF3 Ph-4-CF3
H T-12 CF3 Ph-4-OCF3
H T-13 CF3 (L-45c)CF3
H T-14 CF3 Ph-4-Br
H T-15 CF3 Ph-4-CF3
H M-8a CF3 Ph-4-OCF3
H M-9a CF3 (L-45c)CF3
H M-9b CF3 Ph-4-Br
H M-9c CF3 Ph-4-CF3
H M-19a CF3 Ph-4-OCF3
H CH2NHC(O)OCH3 CF3 (L-45c)CF3
H CH2NHC(O)OEt CF3 Ph-4-Br
H CH2NHC(O)OPr-i CF3 Ph-4-Br
H CH2NHC(O)OPr-i CF3 Ph-4-CF3
H CH2NHC(O)OPr-i CF3 Ph-4-OCF3
H CH2NHC(O)OPr-i CF3 (L-45c)CF3
H CH2CH2NHC(O)CH3 CF3 Ph-4-CF3
H CH2CH2NHC(O)N(CH3)2 CF3 Ph-4-OCF3
H CH2CH2NHC(O)Ph CF3 (L-45c)CF3
H CH2CH2N(CH3)OCH3 CF3 Ph-4-Br
H CH(CH3)CH2NHC(O)CH3 CF3 Ph-4-Br
H CH(CH3)CH2NHC(O)CH3 CF3 Ph-4-CF3
H CH(CH3)CH2NHC(O)CH3 CF3 Ph-4-OCF3
H CH(CH3)CH2NHC(O)CH3 CF3 (L-45c)CF3
H CH(CH3)CH2NHC(O)Et CF3 Ph-4-CF3
H CH(CH3)CH2NHC(O)OCH3 CF3 Ph-4-OCF3
H CH(CH3)CH2NHC(O)N(CH3)2 CF3 (L-45c)CF3
H CH(CH3)CH2NHC(S)NHEt CF3 Ph-4-Br
H CH(CH3)CH2NHSO2CH3 CF3 Ph-4-CF3
H CH(CH3)CH2NHSO2Et CF3 Ph-4-OCF3
H CH(CH3)CH2NHSO2Ph CF3 (L-45c)CF3
H CH(CH3)CH2NHSO2N(CH3)2 CF3 Ph-4-Br
H CH(CH3)CH2NHP(S)(OCH3)2 CF3 Ph-4-CF3
H CH(CH3)CH2NHP(S)(OEt)2 CF3 Ph-4-OCF3
H CH(CH3)CH2N(CH3)2 CF3 (L-45c)CF3
H CH(CH3)CH2N(CH3)SO2CH3 CH3 Ph-4-Br
H CH(CH3)CH2N(CH3)SO2CH3 CH3 Ph-4-CF3
H CH(CH3)CH2N(CH3)SO2CH3 CH3 Ph-4-OCF3
H CH(CH3)CH2N(CH3)SO2CH3 CH3 (L-45c)Cl
H CH(CH3)CH2N(CH3)SO2CH3 CH3 (L-45c)Br
H CH(CH3)CH2N(CH3)SO2CH3 CH3 (L-45c)CF3
H CH(CH3)CH2N(CH3)SO2CH3 Et Ph-4-Br
H CH(CH3)CH2N(CH3)SO2CH3 n-Pr Ph-4-CF3
H CH(CH3)CH2N(CH3)SO2CH3 i-Pr Ph-4-OCF3
H CH(CH3)CH2N(CH3)SO2CH3 c-Pr (L-45c)CF3
H CH(CH3)CH2N(CH3)SO2CH3 CHF2 Ph-4-Br
H CH(CH3)CH2N(CH3)SO2CH3 CF3 CF2O(Ph-4-Cl)
H CH(CH3)CH2N(CH3)SO2CH3 CF3 CH=CH(Ph-4-Cl)
H CH(CH3)CH2N(CH3)SO2CH3 CF3 CH=CH(Ph-4-Br)
H CH(CH3)CH2N(CH3)SO2CH3 CF3 CH=CH(Ph-4-CF3)
H CH(CH3)CH2N(CH3)SO2CH3 CF3 CH=CH(Ph-4-OCF3)
H CH(CH3)CH2N(CH3)SO2CH3 CF3 CH=CH(Ph-3,4-Cl2)
H CH(CH3)CH2N(CH3)SO2CH3 CF3 Ph-4-F
H CH(CH3)CH2N(CH3)SO2CH3 CF3 Ph-4-Cl
H CH(CH3)CH2N(CH3)SO2CH3 CF3 Ph-4-Br
H CH(CH3)CH2N(CH3)SO2CH3 CF3 Ph-4-I
H CH(CH3)CH2N(CH3)SO2CH3 CF3 Ph-4-CF3
H CH(CH3)CH2N(CH3)SO2CH3 CF3 Ph-4-OCHF2
H CH(CH3)CH2N(CH3)SO2CH3 CF3 Ph-4-OCF3
H CH(CH3)CH2N(CH3)SO2CH3 CF3 Ph-4-OCF2Br
H CH(CH3)CH2N(CH3)SO2CH3 CF3 Ph-4-OCF2CHF2
H CH(CH3)CH2N(CH3)SO2CH3 CF3 Ph-4-OCF2CHFCl
H CH(CH3)CH2N(CH3)SO2CH3 CF3 Ph-4-OCF2CHFCF3
H CH(CH3)CH2N(CH3)SO2CH3 CF3 Ph-4-OCF2CHFOCF3
H CH(CH3)CH2N(CH3)SO2CH3 CF3 Ph-4-OCF2CHFOCF2CF2CF3
H CH(CH3)CH2N(CH3)SO2CH3 CF3 Ph-4-O(L-45g)
H CH(CH3)CH2N(CH3)SO2CH3 CF3 Ph-3,4-F2
H CH(CH3)CH2N(CH3)SO2CH3 CF3 Ph-3-F-4-Cl
H CH(CH3)CH2N(CH3)SO2CH3 CF3 Ph-3,4-Cl2
H CH(CH3)CH2N(CH3)SO2CH3 CF3 Ph(-3-OCF2O-4-)
H CH(CH3)CH2N(CH3)SO2CH3 CF3 Ph(-3-OCF2CF2O-4-)
H CH(CH3)CH2N(CH3)SO2CH3 CF3 (L-45c)Cl
H CH(CH3)CH2N(CH3)SO2CH3 CF3 (L-45c)Br
H CH(CH3)CH2N(CH3)SO2CH3 CF3 (L-45c)CF3
H CH(CH3)CH2N(CH3)SO2CH3 CF3 L-45e
H CH(CH3)CH2N(CH3)SO2CH3 CF3 L-45f
H CH(CH3)CH2N(CH3)SO2CH3 CF3 (L-46c)Cl
H CH(CH3)CH2N(CH3)SO2CH3 CF3 (L-46c)Br
H CH(CH3)CH2N(CH3)SO2CH3 CF3 (L-46c)CF3
H CH(CH3)CH2N(CH3)SO2CH3 CF3 L-46d
H CH(CH3)CH2N(CH3)SO2CH3 CF2Cl Ph-4-CF3
H CH(CH3)CH2N(CH3)SO2CH3 CF2Br Ph-4-OCF3
H CH(CH3)CH2N(CH3)SO2CH3 CF2CF3 (L-45c)CF3
H CH(CH3)CH2N(CH3)SO2CH3 CF2CF2CF3 Ph-4-Br
H CH(CH3)CH2N(CH3)SO2CH3 CF2OCH3 Ph-4-CF3
H CH(CH3)CH2N(CH3)SO2CH3 CF2SCH3 Ph-4-OCF3
H C(CH3)2CH2NHC(O)CH3 CF3 (L-45c)CF3
H C(CH3)2CH2NHC(O)Et CF3 Ph-4-Br
H C(CH3)2CH2NHC(O)Pr-c CF3 Ph-4-CF3
H C(CH3)2CH2NHC(O)Bu-t CF3 Ph-4-OCF3
H C(CH3)2CH2NHC(O)CF3 CF3 (L-45c)CF3
H C(CH3)2CH2NHC(O)Ph CF3 Ph-4-Br
H C(CH3)2CH2NHC(O)OCH3 CF3 CF2O(Ph-4-Cl)
H C(CH3)2CH2NHC(O)OCH3 CF3 CH=CH(Ph-4-Cl)
H C(CH3)2CH2NHC(O)OCH3 CF3 CH=CH(Ph-4-Br)
H C(CH3)2CH2NHC(O)OCH3 CF3 CH=CH(Ph-4-CF3)
H C(CH3)2CH2NHC(O)OCH3 CF3 CH=CH(Ph-4-OCF3)
H C(CH3)2CH2NHC(O)OCH3 CF3 CH=CH(Ph-3,4-Cl2)
H C(CH3)2CH2NHC(O)OCH3 CF3 Ph-4-F
H C(CH3)2CH2NHC(O)OCH3 CF3 Ph-4-Cl
H C(CH3)2CH2NHC(O)OCH3 CF3 Ph-4-Br
H C(CH3)2CH2NHC(O)OCH3 CF3 Ph-4-CF3
H C(CH3)2CH2NHC(O)OCH3 CF3 Ph-4-OCF3
H C(CH3)2CH2NHC(O)OCH3 CF3 Ph-4-OCF2Br
H C(CH3)2CH2NHC(O)OCH3 CF3 Ph-4-OCF2CHF2
H C(CH3)2CH2NHC(O)OCH3 CF3 Ph-4-OCF2CHFCF3
H C(CH3)2CH2NHC(O)OCH3 CF3 Ph-4-OCF2CHFOCF3
H C(CH3)2CH2NHC(O)OCH3 CF3 Ph-4-OCF2CHFOCF2CF2CF3
H C(CH3)2CH2NHC(O)OCH3 CF3 Ph-4-O(L-45g)
H C(CH3)2CH2NHC(O)OCH3 CF3 Ph-3,4-F2
H C(CH3)2CH2NHC(O)OCH3 CF3 Ph-3-F-4-Cl
H C(CH3)2CH2NHC(O)OCH3 CF3 Ph-3,4-Cl2
H C(CH3)2CH2NHC(O)OCH3 CF3 Ph(-3-OCF2O-4-)
H C(CH3)2CH2NHC(O)OCH3 CF3 Ph(-3-OCF2CF2O-4-)
H C(CH3)2CH2NHC(O)OCH3 CF3 (L-45c)CF3
H C(CH3)2CH2NHC(O)OCH3 CF3 L-45f
H C(CH3)2CH2NHC(O)OCH3 CF3 (L-46c)CF3
H C(CH3)2CH2NHC(O)OCH3 CF3 L-46d
H C(CH3)2CH2NHC(O)OEt CF3 Ph-4-CF3
H C(CH3)2CH2NHC(O)OPr-n CF3 Ph-4-OCF3
H CH2CH2CH2NHC(O)OCH3 CF3 (L-45c)CF3
H CH2CH2CH2NHC(O)OBu-t CF3 Ph-4-Br
H CH2CH2CH2N(CH3)2 CF3 Ph-4-CF3
H CH2CH2CH2N(CH3)OCH3 CF3 Ph-4-OCF3
H (M-22a)CHO CF3 (L-45c)CF3
H (M-22a)C(O)CH3 CF3 Ph-4-Br
H (M-22a)C(O)OCH3 CF3 Ph-4-CF3
H (M-22a)C(O)OEt CF3 Ph-4-OCF3
H (M-22a)C(O)SCH3 CF3 (L-45c)CF3
H CH2Si(CH3)3 CF3 Ph-4-Br
H C(CH3)2CHO CF3 Ph-4-CF3
H CH(CH3)C(O)CH3 CF3 Ph-4-OCF3
H CH(CHO)CH2SO2CH3 CF3 (L-45c)CF3
H C(CH3)(CHO)CH2SO2CH3 CF3 Ph-4-Br
H C(CH3)(CHO)CH2SO2Et CF3 Ph-4-CF3
H CH2CH=NOCH3 CF3 Ph-4-OCF3
H CH2C(Ph)=NOCH3 CF3 (L-45c)CF3
H CH(CH3)CH=NOCH3 CH3 Ph-4-Br
H CH(CH3)CH=NOCH3 CH3 Ph-4-CF3
H CH(CH3)CH=NOCH3 CH3 Ph-4-OCF3
H CH(CH3)CH=NOCH3 CH3 (L-45c)Cl
H CH(CH3)CH=NOCH3 CH3 (L-45c)Br
H CH(CH3)CH=NOCH3 CH3 (L-45c)CF3
H CH(CH3)CH=NOCH3 Et Ph-4-Br
H CH(CH3)CH=NOCH3 n-Pr Ph-4-CF3
H CH(CH3)CH=NOCH3 i-Pr Ph-4-OCF3
H CH(CH3)CH=NOCH3 c-Pr (L-45c)CF3
H CH(CH3)CH=NOCH3 CHF2 Ph-4-Br
H CH(CH3)CH=NOCH3 CF3 CF2O(Ph-4-Cl)
H CH(CH3)CH=NOCH3 CF3 CH=CH(Ph-4-Cl)
H CH(CH3)CH=NOCH3 CF3 CH=CH(Ph-4-Br)
H CH(CH3)CH=NOCH3 CF3 CH=CH(Ph-4-CF3)
H CH(CH3)CH=NOCH3 CF3 CH=CH(Ph-4-OCF3)
H CH(CH3)CH=NOCH3 CF3 CH=CH(Ph-3,4-Cl2)
H CH(CH3)CH=NOCH3 CF3 Ph-4-F
H CH(CH3)CH=NOCH3 CF3 Ph-4-Cl
H CH(CH3)CH=NOCH3 CF3 Ph-4-Br
H CH(CH3)CH=NOCH3 CF3 Ph-4-I
H CH(CH3)CH=NOCH3 CF3 Ph-4-CF3
H CH(CH3)CH=NOCH3 CF3 Ph-4-OCHF2
H CH(CH3)CH=NOCH3 CF3 Ph-4-OCF3
H CH(CH3)CH=NOCH3 CF3 Ph-4-OCF2Br
H CH(CH3)CH=NOCH3 CF3 Ph-4-OCF2CHF2
H CH(CH3)CH=NOCH3 CF3 Ph-4-OCF2CHFCl
H CH(CH3)CH=NOCH3 CF3 Ph-4-OCF2CHFCF3
H CH(CH3)CH=NOCH3 CF3 Ph-4-OCF2CHFOCF3
H CH(CH3)CH=NOCH3 CF3 Ph-4-OCF2CHFOCF2CF2CF3
H CH(CH3)CH=NOCH3 CF3 Ph-4-O(L-45g)
H CH(CH3)CH=NOCH3 CF3 Ph-3,4-F2
H CH(CH3)CH=NOCH3 CF3 Ph-3-F-4-Cl
H CH(CH3)CH=NOCH3 CF3 Ph-3,4-Cl2
H CH(CH3)CH=NOCH3 CF3 Ph(-3-OCF2O-4-)
H CH(CH3)CH=NOCH3 CF3 Ph(-3-OCF2CF2O-4-)
H CH(CH3)CH=NOCH3 CF3 (L-45c)Cl
H CH(CH3)CH=NOCH3 CF3 (L-45c)Br
H CH(CH3)CH=NOCH3 CF3 (L-45c)CF3
H CH(CH3)CH=NOCH3 CF3 L-45e
H CH(CH3)CH=NOCH3 CF3 L-45f
H CH(CH3)CH=NOCH3 CF3 (L-46c)Cl
H CH(CH3)CH=NOCH3 CF3 (L-46c)Br
H CH(CH3)CH=NOCH3 CF3 (L-46c)CF3
H CH(CH3)CH=NOCH3 CF3 L-46d
H CH(CH3)CH=NOCH3 CF2Cl Ph-4-CF3
H CH(CH3)CH=NOCH3 CF2Br Ph-4-OCF3
H CH(CH3)CH=NOCH3 CF2CF3 (L-45c)CF3
H CH(CH3)CH=NOCH3 CF2CF2CF3 Ph-4-Br
H CH(CH3)CH=NOCH3 CF2OCH3 Ph-4-CF3
H CH(CH3)CH=NOCH3 CF2SCH3 Ph-4-OCF3
H CH(CH3)CH=NOPr-n CF3 Ph-4-Br
H CH(CH3)CH=NOPr-n CF3 Ph-4-CF3
H CH(CH3)CH=NOPr-n CF3 Ph-4-OCF3
H CH(CH3)CH=NOPr-n CF3 (L-45c)CF3
H CH(CH3)CH=NOCH2Pr-c CF3 (L-45c)CF3
H CH(CH3)CH=NOCH2CH2OEt CF3 Ph-4-Br
H CH(CH3)CH=NOCH2CH2SEt CF3 Ph-4-CF3
H CH(CH3)CH=NOCH2CH=CH2 CF3 Ph-4-OCF3
H CH(CH3)CH=NOCH2Ph CF3 (L-45c)CF3
H CH(CH3)C(CH3)=NOCH3 CF3 Ph-4-Br
H C(CH3)2CH=NOH CF3 Ph-4-Br
H C(CH3)2CH=NOH CF3 Ph-4-CF3
H C(CH3)2CH=NOH CF3 Ph-4-OCF3
H C(CH3)2CH=NOH CF3 (L-45c)CF3
H C(CH3)2CH=NOCH3 CF3 CF2O(Ph-4-Cl)
H C(CH3)2CH=NOCH3 CF3 CH=CH(Ph-4-Cl)
H C(CH3)2CH=NOCH3 CF3 CH=CH(Ph-4-Br)
H C(CH3)2CH=NOCH3 CF3 CH=CH(Ph-4-CF3)
H C(CH3)2CH=NOCH3 CF3 CH=CH(Ph-4-OCF3)
H C(CH3)2CH=NOCH3 CF3 CH=CH(Ph-3,4-Cl2)
H C(CH3)2CH=NOCH3 CF3 Ph-4-F
H C(CH3)2CH=NOCH3 CF3 Ph-4-Cl
H C(CH3)2CH=NOCH3 CF3 Ph-4-Br
H C(CH3)2CH=NOCH3 CF3 Ph-4-CF3
H C(CH3)2CH=NOCH3 CF3 Ph-4-OCF3
H C(CH3)2CH=NOCH3 CF3 Ph-4-OCF2Br
H C(CH3)2CH=NOCH3 CF3 Ph-4-OCF2CHF2
H C(CH3)2CH=NOCH3 CF3 Ph-4-OCF2CHFCF3
H C(CH3)2CH=NOCH3 CF3 Ph-4-OCF2CHFOCF3
H C(CH3)2CH=NOCH3 CF3 Ph-4-OCF2CHFOCF2CF2CF3
H C(CH3)2CH=NOCH3 CF3 Ph-4-O(L-45g)
H C(CH3)2CH=NOCH3 CF3 Ph-3,4-F2
H C(CH3)2CH=NOCH3 CF3 Ph-3-F-4-Cl
H C(CH3)2CH=NOCH3 CF3 Ph-3,4-Cl2
H C(CH3)2CH=NOCH3 CF3 Ph(-3-OCF2O-4-)
H C(CH3)2CH=NOCH3 CF3 Ph(-3-OCF2CF2O-4-)
H C(CH3)2CH=NOCH3 CF3 (L-45c)CF3
H C(CH3)2CH=NOCH3 CF3 L-45f
H C(CH3)2CH=NOCH3 CF3 (L-46c)CF3
H C(CH3)2CH=NOCH3 CF3 L-46d
H C(CH3)2CH=NOEt CF3 Ph-4-CF3
H C(CH3)2CH=NOCH2C(O)OBu-t CF3 Ph-4-OCF3
H C(CH3)2CH=NOCH2C(O)N(Et)2 CF3 (L-45c)CF3
H C(CH3)(CH2SO2CH3)CH=NOH CF3 Ph-4-Br
H C(CH3)(CH2SO2Et)CH=NOH CF3 Ph-4-CF3
H CH2CH2CH=NOCH3 CF3 Ph-4-OCF3
H CH(CH3)CH2CH=NOCH3 CF3 (L-45c)CF3
H CH2CH2CH2CH=NOEt CF3 Ph-4-Br
H CH2C(O)OEt CF3 Ph-4-CF3
H CH(CH3)C(O)OCH3 CF3 Ph-4-OCF3
H CH(CH3)C(O)OEt CF3 (L-45c)CF3
H CH2CH2C(O)OEt CF3 Ph-4-Br
H CH(CH3)CH2C(O)OEt CF3 Ph-4-CF3
H CH(CH3)C(O)NHEt CF3 Ph-4-OCF3
H CH(CH3)C(O)NHPr-n CF3 (L-45c)CF3
H CH(CH3)C(O)NHBu-n CF3 Ph-4-Br
H CH(CH3)C(O)NHCH2Ph CF3 Ph-4-CF3
H CH(CH3)C(O)N(CH3)2 CF3 Ph-4-OCF3
H CH(CH3)C(O)N(Et)2 CF3 (L-45c)CF3
H CH(CH3)C(O)N(Pr-n)2 CF3 Ph-4-Br
H CH(CH3)C(O)(T-16) CF3 Ph-4-CF3
H CH(CH3)C(O)(T-17) CF3 Ph-4-OCF3
H CH(CH3)C(O)(T-18) CF3 (L-45c)CF3
H CH(CH3)C(O)(T-19) CF3 Ph-4-Br
H CH(CH3)C(O)(T-20) CF3 Ph-4-CF3
H CH(CH3)C(O)(T-21) CF3 Ph-4-OCF3
H CH(CH3)CH2C(O)NHCH3 CF3 (L-45c)CF3
H CH(CH3)CH2C(O)NHEt CF3 Ph-4-Br
H CH(CH3)CH2C(O)N(CH3)2 CF3 Ph-4-CF3
H CH(CH3)CH2C(O)N(Et)2 CF3 Ph-4-OCF3
H CH(CH3)CH2C(O)N(CH3)Ph CF3 (L-45c)CF3
H CH(CH3)CN CF3 Ph-4-Br
H C(CH3)2CN CF3 Ph-4-CF3
H CH2CH=CH2 CF3 Ph-4-OCF3
CH2CH=CH2 CH2CH=CH2 CF3 (L-45c)CF3
H C(CH3)2CH=CH2 CF3 CH=CH(Ph-4-Cl)
H C(CH3)2CH=CH2 CF3 Ph-4-Cl
H C(CH3)2CH=CH2 CF3 Ph-4-Br
H C(CH3)2CH=CH2 CF3 Ph-4-CF3
H C(CH3)2CH=CH2 CF3 Ph-4-OCF3
H C(CH3)2CH=CH2 CF3 Ph-4-OCF2Br
H C(CH3)2CH=CH2 CF3 Ph-4-OCF2CHFCF3
H C(CH3)2CH=CH2 CF3 Ph-4-OCF2CHFOCF3
H C(CH3)2CH=CH2 CF3 Ph-4-OCF2CHFOCF2CF2CF3
H C(CH3)2CH=CH2 CF3 Ph-4-O(L-45g)
H C(CH3)2CH=CH2 CF3 Ph-3,4-Cl2
H C(CH3)2CH=CH2 CF3 Ph(-3-OCF2O-4-)
H C(CH3)2CH=CH2 CF3 Ph(-3-OCF2CF2O-4-)
H C(CH3)2CH=CH2 CF3 (L-45c)CF3
H C(CH3)2CH=CH2 CF3 L-45f
H C(CH3)2CH=CH2 CF3 (L-46c)CF3
H C(CH3)2CH=CH2 CF3 L-46d
H C(CH3)2CH=CHC(O)NHEt CF3 Ph-4-Br
H C(CH3)2CH=CHPh(E) CF3 Ph-4-CF3
H CH2C≡CH CF3 Ph-4-OCF3
CH3 CH2C≡CH CF3 Ph-4-Br
CH3 CH2C≡CH CF3 Ph-4-CF3
CH3 CH2C≡CH CF3 Ph-4-OCF3
CH3 CH2C≡CH CF3 (L-45c)CF3
H C(CH3)2C≡CH CF3 CH=CH(Ph-4-Cl)
H C(CH3)2C≡CH CF3 Ph-4-Cl
H C(CH3)2C≡CH CF3 Ph-4-Br
H C(CH3)2C≡CH CF3 Ph-4-CF3
H C(CH3)2C≡CH CF3 Ph-4-OCF3
H C(CH3)2C≡CH CF3 Ph-4-OCF2Br
H C(CH3)2C≡CH CF3 Ph-4-OCF2CHFCF3
H C(CH3)2C≡CH CF3 Ph-4-OCF2CHFOCF3
H C(CH3)2C≡CH CF3 Ph-4-OCF2CHFOCF2CF2CF3
H C(CH3)2C≡CH CF3 Ph-4-O(L-45g)
H C(CH3)2C≡CH CF3 Ph-3,4-Cl2
H C(CH3)2C≡CH CF3 Ph(-3-OCF2O-4-)
H C(CH3)2C≡CH CF3 Ph(-3-OCF2CF2O-4-)
H C(CH3)2C≡CH CF3 (L-45c)CF3
H C(CH3)2C≡CH CF3 L-45f
H C(CH3)2C≡CH CF3 (L-46c)CF3
H C(CH3)2C≡CH CF3 L-46d
H C(CH3)2C≡CPh CF3 (L-45c)CF3
H C(CH3)2C≡C(Ph-4-CH3) CF3 Ph-4-Br
H C(CH3)2C≡C(Ph-4-CF3) CF3 Ph-4-CF3
H C(CH3)2C≡C(Ph-4-OCH3) CF3 Ph-4-OCF3
H C(CH3)2C≡C(Ph-4-OCF3) CF3 (L-45c)CF3
H C(CH3)2C≡C(Ph-2,4-F2) CF3 Ph-4-Br
H C(CH3)2C≡C(Ph-2,4-Cl2) CF3 Ph-4-CF3
H C(CH3)2C≡C(Ph-2,6-Cl2) CF3 Ph-4-OCF3
H C(CH3)2C≡C(1-Naph) CF3 (L-45c)CF3
H C(CH3)2C≡C(L-3a) CF3 Ph-4-Br
H C(CH3)2C≡C(L-4a) CF3 Ph-4-CF3
H C(CH3)2C≡C(L-45a) CF3 Ph-4-OCF3
H C(CH3)2C≡C(L-45g) CF3 (L-45c)CF3
H C(CH3)2C≡C(L-46a) CF3 Ph-4-Br
H CH2Ph CF3 Ph-4-CF3
CH3 CH2Ph CF3 Ph-4-OCF3
Et CH2Ph CF3 (L-45c)CF3
H CH2(Ph-2-F) CF3 Ph-4-Br
CH3 CH2(Ph-2-F) CF3 Ph-4-CF3
H CH2(Ph-2-Cl) CF3 Ph-4-OCF3
H CH2(Ph-3-Cl) CF3 (L-45c)CF3
CH3 CH2(Ph-3-Cl) CF3 Ph-4-Br
H CH2(Ph-4-Cl) CF3 Ph-4-CF3
H CH2(Ph-2-CH3) CF3 Ph-4-OCF3
H CH2(Ph-3-CH3) CF3 (L-45c)CF3
H CH2(Ph-4-CH3) CF3 Ph-4-Br
H CH2(Ph-2-CF3) CF3 Ph-4-CF3
H CH2(Ph-2-OCH3) CF3 Ph-4-OCF3
H CH2(Ph-3-OCH3) CF3 (L-45c)CF3
H CH2(Ph-4-OCH3) CF3 Ph-4-Br
H CH2(Ph-4-OCF3) CF3 Ph-4-CF3
H CH2(Ph-2,3-Cl2) CF3 Ph-4-OCF3
H CH2(Ph-2,4-Cl2) CF3 (L-45c)CF3
H CH2(Ph-3,4-Cl2) CF3 Ph-4-Br
H CH2(L-45a) CF3 Ph-4-CF3
H CH2(L-46a) CF3 Ph-4-OCF3
H CH2(L-47a) CF3 (L-45c)CF3
H CH(CH3)Ph CF3 Ph-4-Br
H CH(CH3)Ph(R) CF3 Ph-4-CF3
H CH(CH3)Ph(S) CF3 Ph-4-OCF3
H CH(CH3)(Ph-2-Cl) CF3 (L-45c)CF3
H CH(CH3)(Ph-3-Cl) CF3 Ph-4-Br
H CH(CH3)(Ph-4-Cl) CF3 Ph-4-CF3
H CH(CH3)(L-1a) CF3 Ph-4-OCF3
H CH(CH3)(L-3a) CF3 (L-45c)CF3
H CH(CH3)(L-45a) CF3 Ph-4-Br
H C(CH3)2Ph CF3 Ph-4-CF3
H C(CH3)2(Ph-3-Cl) CF3 Ph-4-OCF3
H C(CH3)2(Ph-4-Cl) CF3 (L-45c)CF3
H CH2CH2Ph CF3 Ph-4-Br
H CH2CH2(Ph-2-Cl) CF3 Ph-4-CF3
H CH2CH2(Ph-3-Cl) CF3 Ph-4-OCF3
H CH2CH2(Ph-4-Cl) CF3 (L-45c)CF3
H CH2CH2(L-46a) CF3 Ph-4-Br
H C(CH3)2CH2Ph CF3 Ph-4-CF3
H CH2CH2CH2Ph CF3 Ph-4-OCF3
H OCH3 CF3 (L-45c)CF3
H OPr-n CF3 Ph-4-Br
H OCH2CH=CHCl CF3 Ph-4-CF3
H OCH2Ph CF3 Ph-4-OCF3
H NHCHO CF3 (L-45c)CF3
H NHC(O)CH3 CF3 Ph-4-Br
H NHC(O)Ph CF3 Ph-4-CF3
H NHC(O)OCH3 CF3 Ph-4-OCF3
H NHC(O)OPh CF3 (L-45c)CF3
H NHC(O)OCH2Ph CF3 Ph-4-Br
H N(CH3)2 CF3 Ph-4-CF3
H N(CH3)CHO CF3 Ph-4-OCF3
H N(CH3)C(O)CH3 CF3 (L-45c)CF3
H N(CH3)C(O)OCH3 CF3 Ph-4-Br
―――――――――――――――――――――――――――――――――――――――
第３表
表中、置換基(X)m及び(Y)nの置換位置を表す番号は、それぞれ下記の構造式に於いて記された番号の位置に対応するものであり、−の表記は、無置換を表す。 ―――――――――――――――――――――――――――――――――――――――
R2        R1                           RFour               RFive
―――――――――――――――――――――――――――――――――――――――
H CHThree                          CFThree              CF2O (Ph-4-Cl)
H CHThree                          CFThree              CH = CH (Ph-4-Cl)
H CHThree                          CFThree              CH = CH (Ph-4-OCFThree)
H CHThree                          CFThree              CH = CH (Ph-3,4-Cl2)
H CHThree                          CFThree              Ph-4-F
H CHThree                          CFThree              Ph-4-Cl
H CHThree                          CFThree              Ph-4-Br
H CHThree                          CFThree              Ph-4-I
H CHThree                          CFThree              Ph-4-CFThree
H CHThree                          CFThree              Ph-4-OCHF2
H CHThree                          CFThree              Ph-4-OCFThree
H CHThree                          CFThree              Ph-4-OCF2Br
H CHThree                          CFThree              Ph-4-OCF2CHF2
H CHThree                          CFThree              Ph-4-OCF2CHFCl
H CHThree                          CFThree              Ph-4-OCF2CHFCFThree
H CHThree                          CFThree              Ph-4-OCF2CHFOCFThree
H CHThree                          CFThree              Ph-4-OCF2CHFOCF2CF2CFThree
H CHThree                          CFThree              Ph-4-O (L-45e)
H CHThree                          CFThree              Ph-3,4-Cl2
H CHThree                          CFThree              Ph (-3-OCF2O-4-)
H CHThree                          CFThree              Ph (-3-OCF2CF2O-4-)
H CHThree                          CFThree             (L-45c) Cl
H CHThree                          CFThree             (L-45c) Br
H CHThree                          CFThree             (L-45c) CFThree
H CHThree                          CFThree              L-45e
H CHThree                          CFThree              L-45f
H CHThree                          CFThree             (L-46c) Cl
H CHThree                          CFThree             (L-46c) Br
H CHThree                          CFThree             (L-46c) CFThree
H CHThree                          CFThree              L-46d
CHThree       CHThree                          CFThree              Ph-4-Br
CHThree       CHThree                          CFThree              Ph-4-CFThree
CHThree       CHThree                          CFThree              Ph-4-OCFThree
CHThree       CHThree                          CFThree             (L-45c) CFThree
H Et CHThree              Ph-4-Cl
H Et CHThree              Ph-4-CFThree
H Et CHThree              Ph-4-OCFThree
H Et CHThree             (L-45c) Cl
H Et CHThree             (L-45c) Br
H Et CHThree             (L-45c) CFThree
H Et Et Ph-4-Br
H Et n-Pr Ph-4-CFThree
H Et i-Pr Ph-4-OCFThree
H Et c-Pr (L-45c) CFThree
H Et CHF2             Ph-4-Br
H Et CFThree              CF2O (Ph-4-Cl)
H Et CFThree              CH = CH (Ph-4-Cl)
H Et CFThree              CH = CH (Ph-4-OCFThree)
H Et CFThree              CH = CH (Ph-3,4-Cl2)
H Et CFThree              Ph-4-F
H Et CFThree              Ph-4-Cl
H Et CFThree              Ph-4-Br
H Et CFThree              Ph-4-I
H Et CFThree              Ph-4-CFThree
H Et CFThree              Ph-4-OCHF2
H Et CFThree              Ph-4-OCFThree
H Et CFThree              Ph-4-OCF2Br
H Et CFThree              Ph-4-OCF2CHF2
H Et CFThree              Ph-4-OCF2CHFCl
H Et CFThree              Ph-4-OCF2CHFCFThree
H Et CFThree              Ph-4-OCF2CHFOCFThree
H Et CFThree              Ph-4-OCF2CHFOCF2CF2CFThree
H Et CFThree              Ph-4-O (L-45g)
H Et CFThree              Ph-3,4-Cl2
H Et CFThree              Ph (-3-OCF2O-4-)
H Et CFThree              Ph (-3-OCF2CF2O-4-)
H Et CFThree             (L-45c) Cl
H Et CFThree             (L-45c) Br
H Et CFThree             (L-45c) CFThree
H Et CFThree              L-45e
H Et CFThree              L-45f
H Et CFThree             (L-46c) Cl
H Et CFThree             (L-46c) Br
H Et CFThree             (L-46c) CFThree
H Et CFThree              L-46d
H Et CF2Cl Ph-4-CFThree
H Et CF2Br Ph-4-OCFThree
H Et CF2CFThree          (L-45c) CFThree
H Et CF2CF2CFThree        Ph-4-Br
H Et CF2OCHThree          Ph-4-CFThree
H Et CF2SCHThree          Ph-4-OCFThree
Et Et CHThree              Ph-4-Br
Et Et CHThree              Ph-4-CFThree
Et Et CHThree              Ph-4-OCFThree
Et Et CHThree             (L-45c) Cl
Et Et CHThree             (L-45c) Br
Et Et CHThree             (L-45c) CFThree
Et Et CFThree              CF2O (Ph-4-Cl)
Et Et CFThree              CH = CH (Ph-4-Cl)
Et Et CFThree              CH = CH (Ph-4-OCFThree)
Et Et CFThree              CH = CH (Ph-3,4-Cl2)
Et Et CFThree              Ph-4-F
Et Et CFThree              Ph-4-Cl
Et Et CFThree              Ph-4-Br
Et Et CFThree              Ph-4-I
Et Et CFThree              Ph-4-CFThree
Et Et CFThree              Ph-4-OCHF2
Et Et CFThree              Ph-4-OCFThree
Et Et CFThree              Ph-4-OCF2Br
Et Et CFThree              Ph-4-OCF2CHF2
Et Et CFThree              Ph-4-OCF2CHFCl
Et Et CFThree              Ph-4-OCF2CHFCFThree
Et Et CFThree              Ph-4-OCF2CHFOCFThree
Et Et CFThree              Ph-4-OCF2CHFOCF2CF2CFThree
Et Et CFThree              Ph-4-O (L-45g)
Et Et CFThree              Ph-3,4-Cl2
Et Et CFThree              Ph (-3-OCF2O-4-)
Et Et CFThree              Ph (-3-OCF2CF2O-4-)
Et Et CFThree             (L-45c) Cl
Et Et CFThree             (L-45c) Br
Et Et CFThree             (L-45c) CFThree
Et Et CFThree              L-45e
Et Et CFThree              L-45f
Et Et CFThree             (L-46c) Cl
Et Et CFThree             (L-46c) Br
Et Et CFThree             (L-46c) CFThree
Et Et CFThree              L-46d
H n-Pr CHThree              Ph-4-Br
H n-Pr CHThree              Ph-4-CFThree
H n-Pr CHThree              Ph-4-OCFThree
H n-Pr CHThree             (L-45c) Cl
H n-Pr CHThree             (L-45c) Br
H n-Pr CHThree             (L-45c) CFThree
H n-Pr Et (L-45c) CFThree
H n-Pr n-Pr Ph-4-Br
H n-Pr i-Pr Ph-4-CFThree
H n-Pr c-Pr Ph-4-OCFThree
H n-Pr CHF2            (L-45c) CFThree
H n-Pr CFThree              CF2O (Ph-4-Cl)
H n-Pr CFThree              CH = CH (Ph-4-Cl)
H n-Pr CFThree              CH = CH (Ph-4-OCFThree)
H n-Pr CFThree              CH = CH (Ph-3,4-Cl2)
H n-Pr CFThree              Ph-4-F
H n-Pr CFThree              Ph-4-Cl
H n-Pr CFThree              Ph-4-Br
H n-Pr CFThree              Ph-4-I
H n-Pr CFThree              Ph-4-CFThree
H n-Pr CFThree              Ph-4-OCHF2
H n-Pr CFThree              Ph-4-OCFThree
H n-Pr CFThree              Ph-4-OCF2Br
H n-Pr CFThree              Ph-4-OCF2CHF2
H n-Pr CFThree              Ph-4-OCF2CHFCl
H n-Pr CFThree              Ph-4-OCF2CHFCFThree
H n-Pr CFThree              Ph-4-OCF2CHFOCFThree
H n-Pr CFThree              Ph-4-OCF2CHFOCF2CF2CFThree
H n-Pr CFThree              Ph-4-O (L-45g)
H n-Pr CFThree              Ph-3,4-Cl2
H n-Pr CFThree              Ph (-3-OCF2O-4-)
H n-Pr CFThree              Ph (-3-OCF2CF2O-4-)
H n-Pr CFThree             (L-45c) Cl
H n-Pr CFThree             (L-45c) Br
H n-Pr CFThree             (L-45c) CFThree
H n-Pr CFThree              L-45e
H n-Pr CFThree              L-45f
H n-Pr CFThree             (L-46c) Cl
H n-Pr CFThree             (L-46c) Br
H n-Pr CFThree             (L-46c) CFThree
H n-Pr CFThree              L-46d
H n-Pr CF2Cl Ph-4-Br
H n-Pr CF2Br Ph-4-CFThree
H n-Pr CF2CFThree           Ph-4-OCFThree
H n-Pr CF2CF2CFThree       (L-45c) CFThree
H n-Pr CF2OCHThree          Ph-4-Br
H n-Pr CF2SCHThree          Ph-4-CFThree
CHThree       n-Pr CFThree              Ph-4-Br
CHThree       n-Pr CFThree              Ph-4-CFThree
CHThree       n-Pr CFThree              Ph-4-OCFThree
CHThree       n-Pr CFThree             (L-45c) CFThree
Et n-Pr CFThree              Ph-4-OCFThree
n-Pr n-Pr CFThree             (L-45c) CFThree
H i-Pr CHThree              CF2O (Ph-4-Cl)
H i-Pr CHThree              CH = CH (Ph-4-Cl)
H i-Pr CHThree              CH = CH (Ph-4-OCFThree)
H i-Pr CHThree              CH = CH (Ph-3,4-Cl2)
H i-Pr CHThree              Ph-4-F
H i-Pr CHThree              Ph-4-Cl
H i-Pr CHThree              Ph-4-Br
H i-Pr CHThree              Ph-4-I
H i-Pr CHThree              Ph-4-CFThree
H i-Pr CHThree              Ph-4-OCHF2
H i-Pr CHThree              Ph-4-OCFThree
H i-Pr CHThree              Ph-4-OCF2Br
H i-Pr CHThree              Ph-4-OCF2CHF2
H i-Pr CHThree              Ph-4-OCF2CHFCl
H i-Pr CHThree              Ph-4-OCF2CHFCFThree
H i-Pr CHThree              Ph-4-OCF2CHFOCFThree
H i-Pr CHThree              Ph-4-OCF2CHFOCF2CF2CFThree
H i-Pr CHThree              Ph-4-O (L-45g)
H i-Pr CHThree              Ph-3,4-Cl2
H i-Pr CHThree              Ph (-3-OCF2O-4-)
H i-Pr CHThree              Ph (-3-OCF2CF2O-4-)
H i-Pr CHThree             (L-45c) Cl
H i-Pr CHThree             (L-45c) Br
H i-Pr CHThree             (L-45c) CFThree
H i-Pr CHThree              L-45e
H i-Pr CHThree              L-45f
H i-Pr CHThree             (L-46c) Cl
H i-Pr CHThree             (L-46c) Br
H i-Pr CHThree             (L-46c) CFThree
H i-Pr CHThree              L-46d
H i-Pr Et CF2O (Ph-4-Cl)
H i-Pr Et CH = CH (Ph-4-Cl)
H i-Pr Et CH = CH (Ph-4-OCFThree)
H i-Pr Et CH = CH (Ph-3,4-Cl2)
H i-Pr Et Ph-4-Cl
H i-Pr Et Ph-4-Br
H i-Pr Et Ph-4-CFThree
H i-Pr Et Ph-4-OCFThree
H i-Pr Et Ph-4-OCF2Br
H i-Pr Et Ph-4-OCF2CHFCFThree
H i-Pr Et Ph-4-OCF2CHFOCFThree
H i-Pr Et Ph-4-OCF2CHFOCF2CF2CFThree
H i-Pr Et Ph-4-O (L-45g)
H i-Pr Et Ph-3,4-Cl2
H i-Pr Et Ph (-3-OCF2O-4-)
H i-Pr Et Ph (-3-OCF2CF2O-4-)
H i-Pr Et (L-45c) Br
H i-Pr Et (L-45c) CFThree
H i-Pr Et L-45e
H i-Pr Et L-45f
H i-Pr Et (L-46c) Br
H i-Pr Et (L-46c) CFThree
H i-Pr Et L-46d
H i-Pr n-Pr CF2O (Ph-4-Cl)
H i-Pr n-Pr CH = CH (Ph-4-Cl)
H i-Pr n-Pr CH = CH (Ph-4-OCFThree)
H i-Pr n-Pr CH = CH (Ph-3,4-Cl2)
H i-Pr n-Pr Ph-4-Cl
H i-Pr n-Pr Ph-4-Br
H i-Pr n-Pr Ph-4-CFThree
H i-Pr n-Pr Ph-4-OCFThree
H i-Pr n-Pr Ph-4-OCF2Br
H i-Pr n-Pr Ph-4-OCF2CHFCFThree
H i-Pr n-Pr Ph-4-OCF2CHFOCFThree
H i-Pr n-Pr Ph-4-OCF2CHFOCF2CF2CFThree
H i-Pr n-Pr Ph-4-O (L-45g)
H i-Pr n-Pr Ph-3,4-Cl2
H i-Pr n-Pr Ph (-3-OCF2O-4-)
H i-Pr n-Pr Ph (-3-OCF2CF2O-4-)
H i-Pr n-Pr (L-45c) Br
H i-Pr n-Pr (L-45c) CFThree
H i-Pr n-Pr L-45e
H i-Pr n-Pr L-45f
H i-Pr n-Pr (L-46c) Br
H i-Pr n-Pr (L-46c) CFThree
H i-Pr n-Pr L-46d
H i-Pr i-Pr CF2O (Ph-4-Cl)
H i-Pr i-Pr CH = CH (Ph-4-Cl)
H i-Pr i-Pr CH = CH (Ph-4-OCFThree)
H i-Pr i-Pr CH = CH (Ph-3,4-Cl2)
H i-Pr i-Pr Ph-4-Cl
H i-Pr i-Pr Ph-4-Br
H i-Pr i-Pr Ph-4-CFThree
H i-Pr i-Pr Ph-4-OCFThree
H i-Pr i-Pr Ph-4-OCF2Br
H i-Pr i-Pr Ph-4-OCF2CHFCFThree
H i-Pr i-Pr Ph-4-OCF2CHFOCFThree
H i-Pr i-Pr Ph-4-OCF2CHFOCF2CF2CFThree
H i-Pr i-Pr Ph-4-O (L-45g)
H i-Pr i-Pr Ph-3,4-Cl2
H i-Pr i-Pr Ph (-3-OCF2O-4-)
H i-Pr i-Pr Ph (-3-OCF2CF2O-4-)
H i-Pr i-Pr (L-45c) Br
H i-Pr i-Pr (L-45c) CFThree
H i-Pr i-Pr L-45e
H i-Pr i-Pr L-45f
H i-Pr i-Pr (L-46c) Br
H i-Pr i-Pr (L-46c) CFThree
H i-Pr i-Pr L-46d
H i-Pr c-Pr CF2O (Ph-4-Cl)
H i-Pr c-Pr CH = CH (Ph-4-Cl)
H i-Pr c-Pr CH = CH (Ph-4-OCFThree)
H i-Pr c-Pr CH = CH (Ph-3,4-Cl2)
H i-Pr c-Pr Ph-4-Cl
H i-Pr c-Pr Ph-4-Br
H i-Pr c-Pr Ph-4-CFThree
H i-Pr c-Pr Ph-4-OCFThree
H i-Pr c-Pr Ph-4-OCF2Br
H i-Pr c-Pr Ph-4-OCF2CHFCFThree
H i-Pr c-Pr Ph-4-OCF2CHFOCFThree
H i-Pr c-Pr Ph-4-OCF2CHFOCF2CF2CFThree
H i-Pr c-Pr Ph-4-O (L-45g)
H i-Pr c-Pr Ph-3,4-Cl2
H i-Pr c-Pr Ph (-3-OCF2O-4-)
H i-Pr c-Pr Ph (-3-OCF2CF2O-4-)
H i-Pr c-Pr (L-45c) Br
H i-Pr c-Pr (L-45c) CFThree
H i-Pr c-Pr L-45e
H i-Pr c-Pr L-45f
H i-Pr c-Pr (L-46c) Br
H i-Pr c-Pr (L-46c) CFThree
H i-Pr c-Pr L-46d
H i-Pr n-Bu Ph-4-Br
H i-Pr s-Bu Ph-4-CFThree
H i-Pr i-Bu Ph-4-OCFThree
H i-Pr c-Bu (L-45c) CFThree
H i-Pr n-Pen Ph-4-Br
H i-Pr c-Pen Ph-4-CFThree
H i-Pr n-Hex Ph-4-OCFThree
H i-Pr c-Hex (L-45c) CFThree
H i-Pr CH2F Ph-4-Br
H i-Pr CH2Cl Ph-4-CFThree
H i-Pr CH2Br Ph-4-OCFThree
H i-Pr CHF2             CF2O (Ph-4-Cl)
H i-Pr CHF2             CH = CH (Ph-4-Cl)
H i-Pr CHF2             CH = CH (Ph-4-OCFThree)
H i-Pr CHF2             CH = CH (Ph-3,4-Cl2)
H i-Pr CHF2             Ph-4-F
H i-Pr CHF2             Ph-4-Cl
H i-Pr CHF2             Ph-4-Br
H i-Pr CHF2             Ph-4-I
H i-Pr CHF2             Ph-4-CFThree
H i-Pr CHF2             Ph-4-OCHF2
H i-Pr CHF2             Ph-4-OCFThree
H i-Pr CHF2             Ph-4-OCF2Br
H i-Pr CHF2             Ph-4-OCF2CHF2
H i-Pr CHF2             Ph-4-OCF2CHFCl
H i-Pr CHF2             Ph-4-OCF2CHFCFThree
H i-Pr CHF2             Ph-4-OCF2CHFOCFThree
H i-Pr CHF2             Ph-4-OCF2CHFOCF2CF2CFThree
H i-Pr CHF2             Ph-4-O (L-45g)
H i-Pr CHF2             Ph-3,4-Cl2
H i-Pr CHF2             Ph (-3-OCF2O-4-)
H i-Pr CHF2             Ph (-3-OCF2CF2O-4-)
H i-Pr CHF2            (L-45c) Cl
H i-Pr CHF2            (L-45c) Br
H i-Pr CHF2            (L-45c) CFThree
H i-Pr CHF2             L-45e
H i-Pr CHF2             L-45f
H i-Pr CHF2            (L-46c) Cl
H i-Pr CHF2            (L-46c) Br
H i-Pr CHF2            (L-46c) CFThree
H i-Pr CHF2             L-46d
H i-Pr CHFCl (L-45c) CFThree
H i-Pr CHFBr Ph-4-Br
H i-Pr CFThree              T-1
H i-Pr CFThree              T-2
H i-Pr CFThree              T-3
H i-Pr CFThree              T-4
H i-Pr CFThree              T-5
H i-Pr CFThree              CH2OCHThree
H i-Pr CFThree              CH2OEt
H i-Pr CFThree              CH2OPr-n
H i-Pr CFThree              CH2OPr-i
H i-Pr CFThree              CH2OBu-n
H i-Pr CFThree              CH2OCH2CFThree
H i-Pr CFThree              CH2OCH2CF2CFThree
H i-Pr CFThree              CH2OCH (CFThree)2
H i-Pr CFThree              CH2OC (O) (Ph-2-Cl)
H i-Pr CFThree              CH2OC (O) (Ph-3-Cl)
H i-Pr CFThree              CH2OC (O) (Ph-4-Cl)
H i-Pr CFThree              CH2OPh
H i-Pr CFThree              CH2O (Ph-4-F)
H i-Pr CFThree              CH2O (Ph-2-Cl)
H i-Pr CFThree              CH2O (Ph-3-Cl)
H i-Pr CFThree              CH2O (Ph-4-Cl)
H i-Pr CFThree              CH2O (Ph-4-Br)
H i-Pr CFThree              CH2O (Ph-4-CFThree)
H i-Pr CFThree              CH2O (Ph-4-OCFThree)
H i-Pr CFThree              CH2CH2OCHThree
H i-Pr CFThree              CF2OPh
H i-Pr CFThree              CF2O (Ph-3-F)
H i-Pr CFThree              CF2O (Ph-4-F)
H i-Pr CFThree              CF2O (Ph-2-Cl)
H i-Pr CFThree              CF2O (Ph-3-Cl)
H i-Pr CFThree              CF2O (Ph-4-Cl)
H i-Pr CFThree              CF2O (Ph-3-Br)
H i-Pr CFThree              CF2O (Ph-4-Br)
H i-Pr CFThree              CF2O (Ph-3-CFThree)
H i-Pr CFThree              CF2O (Ph-4-CFThree)
H i-Pr CFThree              CF2O (Ph-3-OCFThree)
H i-Pr CFThree              CF2O (Ph-4-OCFThree)
H i-Pr CFThree              M-4a
H i-Pr CFThree              M-5a
H i-Pr CFThree              CH2SCHThree
H i-Pr CFThree              CH2SO2CHThree
H i-Pr CFThree              CH2SCFThree
H i-Pr CFThree              CH2SO2CFThree
H i-Pr CFThree              CH2SPh
H i-Pr CFThree              CH2S (Ph-3-Cl)
H i-Pr CFThree              CH2S (Ph-4-Cl)
H i-Pr CFThree              CH2SO2(Ph-3-Cl)
H i-Pr CFThree              CH2SO2(Ph-4-Cl)
H i-Pr CFThree              CH2CH2SCHThree
H i-Pr CFThree              CH2CH2SO2CHThree
H i-Pr CFThree              CH2CH (CHThree) SCHThree
H i-Pr CFThree              CH2CH (CHThree) SEt
H i-Pr CFThree              CH2CH2SCFThree
H i-Pr CFThree              CH2N (CHThree)2
H i-Pr CFThree              CH2NHPh
H i-Pr CFThree              CH2NH (Ph-3-Cl)
H i-Pr CFThree              CH2NH (Ph-4-Cl)
H i-Pr CFThree              CF2C (O) OEt
H i-Pr CFThree              CH2CH2Ph
H i-Pr CFThree              CH2CH2(Ph-3-Cl)
H i-Pr CFThree              CH2CH2(Ph-4-Cl)
H i-Pr CFThree              CH (CHThree) CH2Ph
H i-Pr CFThree              CH2(L-5a)
H i-Pr CFThree              CH2(L-14a)
H i-Pr CFThree              CH2(L-24a)
H i-Pr CFThree              CH2(L-36a)
H i-Pr CFThree              T-22
H i-Pr CFThree              T-23
H i-Pr CFThree              T-24
H i-Pr CFThree              C (O) OCHThree
H i-Pr CFThree              C (O) OEt
H i-Pr CFThree              C (O) OPr-n
H i-Pr CFThree              C (O) OPr-i
H i-Pr CFThree              C (O) OBu-n
H i-Pr CFThree              C (O) OBu-t
H i-Pr CFThree              C (O) OCH2CFThree
H i-Pr CFThree              C (O) SEt
H i-Pr CFThree              C (O) N (CHThree)2
H i-Pr CFThree              CH = CHPh
H i-Pr CFThree              CH = CH (Ph-3-F)
H i-Pr CFThree              CH = CH (Ph-4-F)
H i-Pr CFThree              CH = CH (Ph-2-Cl)
H i-Pr CFThree              CH = CH (Ph-3-Cl)
H i-Pr CFThree              CH = CH (Ph-4-Cl)
H i-Pr CFThree              CH = CH (Ph-3-Br)
H i-Pr CFThree              CH = CH (Ph-4-Br)
H i-Pr CFThree              CH = CH (Ph-3-CFThree)
H i-Pr CFThree              CH = CH (Ph-4-CFThree)
H i-Pr CFThree              CH = CH (Ph-3-OCFThree)
H i-Pr CFThree              CH = CH (Ph-4-OCFThree)
H i-Pr CFThree              CH = CH (Ph-3-SCHThree)
H i-Pr CFThree              CH = CH (Ph-4-SCHThree)
H i-Pr CFThree              CH = CH (Ph-3-SO2CHThree)
H i-Pr CFThree              CH = CH (Ph-4-SO2CHThree)
H i-Pr CFThree              CH = CH (Ph-3,4-F2)
H i-Pr CFThree              CH = CH (Ph-3-F-4-Cl)
H i-Pr CFThree              CH = CH (Ph-3,4-Cl2)
H i-Pr CFThree              CH = CH (Ph-3,4-Br2)
H i-Pr CFThree              CH = CH (Ph-3-F-4-CFThree)
H i-Pr CFThree              CH = CH (Ph-3-Cl-4-OCFThree)
H i-Pr CFThree              CH = CH [Ph (-3-OCF2O-4-)]
H i-Pr CFThree              Ph
H i-Pr CFThree              Ph-3-F
H i-Pr CFThree              Ph-4-F
H i-Pr CFThree              Ph-2-Cl
H i-Pr CFThree              Ph-3-Cl
H i-Pr CFThree              Ph-4-Cl
H i-Pr CFThree              Ph-3-Br
H i-Pr CFThree              Ph-4-Br
H i-Pr CFThree              Ph-3-I
H i-Pr CFThree              Ph-4-I
H i-Pr CFThree              Ph-4-CHThree
H i-Pr CFThree              Ph-4-Et
H i-Pr CFThree              Ph-4-Pr-n
H i-Pr CFThree              Ph-4-Pr-i
H i-Pr CFThree              Ph-4-Bu-n
H i-Pr CFThree              Ph-4-Bu-i
H i-Pr CFThree              Ph-4-Bu-t
H i-Pr CFThree              Ph-3-CFThree
H i-Pr CFThree              Ph-4-CFThree
H i-Pr CFThree              Ph-4-C (CFThree)2OH
H i-Pr CFThree              Ph-4-C (CFThree)2OCHThree
H i-Pr CFThree              Ph-4-CH2OCHThree
H i-Pr CFThree              Ph-4-CH2OCH2CFThree
H i-Pr CFThree              Ph-4-CH2SCHThree
H i-Pr CFThree              Ph-4-CH2S (O) CHThree
H i-Pr CFThree              Ph-4-CH2SO2CHThree
H i-Pr CFThree              Ph-4-CH2SEt
H i-Pr CFThree              Ph-4-CH2S (O) Et
H i-Pr CFThree              Ph-4-CH2SO2Et
H i-Pr CFThree              Ph-4-CH2SPr-n
H i-Pr CFThree              Ph-4-CH2SO2Pr-n
H i-Pr CFThree              Ph-4-CH2SPr-i
H i-Pr CFThree              Ph-4-CH2SO2Pr-i
H i-Pr CFThree              Ph-4-CH2SPr-c
H i-Pr CFThree              Ph-4-CH2SO2Pr-c
H i-Pr CFThree              Ph-4-CH2SBu-n
H i-Pr CFThree              Ph-4-CH2SO2Bu-n
H i-Pr CFThree              Ph-4-CH2SCFThree
H i-Pr CFThree              Ph-4-CH2S (O) CFThree
H i-Pr CFThree              Ph-4-CH2SO2CFThree
H i-Pr CFThree              Ph-4-CH2SCH2CFThree
H i-Pr CFThree              Ph-4-OH
H i-Pr CFThree              Ph-4-OCHThree
H i-Pr CFThree              Ph-4-OEt
H i-Pr CFThree              Ph-4-OPr-n
H i-Pr CFThree              Ph-4-OPr-i
H i-Pr CFThree              Ph-4-OBu-n
H i-Pr CFThree              Ph-4-OBu-t
H i-Pr CFThree              Ph-4-OCHF2
H i-Pr CFThree              Ph-3-OCFThree
H i-Pr CFThree              Ph-4-OCFThree
H i-Pr CFThree              Ph-4-OCF2Br
H i-Pr CFThree              Ph-4-OCH2CFThree
H i-Pr CFThree              Ph-4-OCF2CHF2
H i-Pr CFThree              Ph-4-OCF2CHFCl
H i-Pr CFThree              Ph-4-OCF2CHFBr
H i-Pr CFThree              Ph-4-OCF2CF2Br
H i-Pr CFThree              Ph-4-OCF2CFCl2
H i-Pr CFThree              Ph-4-OCF2CClThree
H i-Pr CFThree              Ph-4-OCH2CF2CHF2
H i-Pr CFThree              Ph-3-OCF2CHFCFThree
H i-Pr CFThree              Ph-4-OCF2CHFCFThree
H i-Pr CFThree              Ph-4-OCH (CFThree)2
H i-Pr CFThree              Ph-4-OCF2CFBrCFThree
H i-Pr CFThree              Ph-3-OCF2CHFOCFThree
H i-Pr CFThree              Ph-4-OCF2CHFOCFThree
H i-Pr CFThree              Ph-4-OCF2CHFOCF2CF2CFThree
H i-Pr CFThree              Ph-4-OCH2CH = CH2
H i-Pr CFThree              Ph-4-OCH2CH = CF2
H i-Pr CFThree              Ph-4-OCH2CF = CF2
H i-Pr CFThree              Ph-4-OCH2CH = CCl2
H i-Pr CFThree              Ph-4-OCH2CCl = CCl2
H i-Pr CFThree              Ph-4-OCH2Ph
H i-Pr CFThree              Ph-4-OSO2CHThree
H i-Pr CFThree              Ph-4-OSO2Et
H i-Pr CFThree              Ph-4-OSO2Pr-n
H i-Pr CFThree              Ph-4-OSO2Pr-i
H i-Pr CFThree              Ph-4-OSO2Bu-n
H i-Pr CFThree              Ph-4-OSO2CHCl2
H i-Pr CFThree              Ph-4-OSO2CFThree
H i-Pr CFThree              Ph-4-OSO2CH2CFThree
H i-Pr CFThree              Ph-3-O (Ph-4-Cl)
H i-Pr CFThree              Ph-4-O (Ph-4-Cl)
H i-Pr CFThree              Ph-4-O (Ph-4-Br)
H i-Pr CFThree              Ph-4-O (Ph-4-CFThree)
H i-Pr CFThree              Ph-4-O (L-21b) Br
H i-Pr CFThree              Ph-4-O (L-21b) CFThree
H i-Pr CFThree              Ph-3-O (L-45c) Br
H i-Pr CFThree              Ph-4-O (L-45c) Br
H i-Pr CFThree              Ph-3-O (L-45c) CFThree
H i-Pr CFThree              Ph-4-O (L-45c) CFThree
H i-Pr CFThree              Ph-3-O (L-45e)
H i-Pr CFThree              Ph-4-O (L-45e)
H i-Pr CFThree              Ph-3-O (L-48b) Br
H i-Pr CFThree              Ph-4-O (L-48b) Br
H i-Pr CFThree              Ph-4-SCHThree
H i-Pr CFThree              Ph-4-S (O) CHThree
H i-Pr CFThree              Ph-4-SO2CHThree
H i-Pr CFThree              Ph-4-SEt
H i-Pr CFThree              Ph-4-S (O) Et
H i-Pr CFThree              Ph-4-SO2Et
H i-Pr CFThree              Ph-4-SPr-n
H i-Pr CFThree              Ph-4-S (O) Pr-n
H i-Pr CFThree              Ph-4-SO2Pr-n
H i-Pr CFThree              Ph-4-SPr-i
H i-Pr CFThree              Ph-4-S (O) Pr-i
H i-Pr CFThree              Ph-4-SO2Pr-i
H i-Pr CFThree              Ph-4-SBu-n
H i-Pr CFThree              Ph-4-S (O) Bu-n
H i-Pr CFThree              Ph-4-SO2Bu-n
H i-Pr CFThree              Ph-4-SBu-t
H i-Pr CFThree              Ph-4-S (O) Bu-t
H i-Pr CFThree              Ph-4-SO2Bu-t
H i-Pr CFThree              Ph-4-SCH2F
H i-Pr CFThree              Ph-4-S (O) CH2F
H i-Pr CFThree              Ph-4-SO2CH2F
H i-Pr CFThree              Ph-4-SCHF2
H i-Pr CFThree              Ph-4-S (O) CHF2
H i-Pr CFThree              Ph-4-SO2CHF2
H i-Pr CFThree              Ph-3-SCFThree
H i-Pr CFThree              Ph-4-SCFThree
H i-Pr CFThree              Ph-4-S (O) CFThree
H i-Pr CFThree              Ph-4-SO2CFThree
H i-Pr CFThree              Ph-4-SCF2Cl
H i-Pr CFThree              Ph-4-S (O) CF2Cl
H i-Pr CFThree              Ph-4-SO2CF2Cl
H i-Pr CFThree              Ph-4-SCF2Br
H i-Pr CFThree              Ph-4-S (O) CF2Br
H i-Pr CFThree              Ph-4-SO2CF2Br
H i-Pr CFThree              Ph-3-S (Ph-4-Cl)
H i-Pr CFThree              Ph-4-S (Ph-4-Cl)
H i-Pr CFThree              Ph-4-S (Ph-4-Br)
H i-Pr CFThree              Ph-4-S (Ph-4-CFThree)
H i-Pr CFThree              Ph-4-S (L-45c) Br
H i-Pr CFThree              Ph-4-S (L-45c) CFThree
H i-Pr CFThree              Ph-4-S (L-45e)
H i-Pr CFThree              Ph-4-S (L-48b) Br
H i-Pr CFThree              Ph-4-NO2
H i-Pr CFThree              Ph-4-N (CHThree)2
H i-Pr CFThree              Ph-4-N (Et)2
H i-Pr CFThree              Ph-4- (T-16)
H i-Pr CFThree              Ph-4-CN
H i-Pr CFThree              Ph-4-C (O) OCHThree
H i-Pr CFThree              Ph-4-C (O) NH2
H i-Pr CFThree              Ph-4-C (O) NHCHThree
H i-Pr CFThree              Ph-4-C (O) NHEt
H i-Pr CFThree              Ph-4-C (O) N (CHThree)2
H i-Pr CFThree              Ph-4-C (S) NH2
H i-Pr CFThree              Ph-3-Ph
H i-Pr CFThree              Ph-4-Ph
H i-Pr CFThree              Ph-4- (L-5a)
H i-Pr CFThree              Ph-4- (L-14a)
H i-Pr CFThree              Ph-4- (L-24a)
H i-Pr CFThree              Ph-4- (L-36a)
H i-Pr CFThree              Ph-2,4-F2
H i-Pr CFThree              Ph-3,4-F2
H i-Pr CFThree              Ph-2-Cl-4-F
H i-Pr CFThree              Ph-3-Cl-4-F
H i-Pr CFThree              Ph-2-F-4-Cl
H i-Pr CFThree              Ph-3-F-4-Cl
H i-Pr CFThree              Ph-2,4-Cl2
H i-Pr CFThree              Ph-3,4-Cl2
H i-Pr CFThree              Ph-3,5-Cl2
H i-Pr CFThree              Ph-3-Br-4-F
H i-Pr CFThree              Ph-2-F-4-Br
H i-Pr CFThree              Ph-3,4-Br2
H i-Pr CFThree              Ph-3-CHThree-4-F
H i-Pr CFThree              Ph-3-F-4-CHThree
H i-Pr CFThree              Ph-3,4- (CHThree)2
H i-Pr CFThree              Ph-3-CFThree-4-F
H i-Pr CFThree              Ph-3-CFThree-4-Cl
H i-Pr CFThree              Ph-2-F-4-CFThree
H i-Pr CFThree              Ph-3-F-4-CFThree
H i-Pr CFThree              Ph-2-Cl-4-CFThree
H i-Pr CFThree              Ph-3-Br-4-OCHThree
H i-Pr CFThree              Ph-3-F-4-OCHF2
H i-Pr CFThree              Ph-3-Cl-4-OCHF2
H i-Pr CFThree              Ph-3-Br-4-OCHF2
H i-Pr CFThree              Ph-3-F-4-OCFThree
H i-Pr CFThree              Ph-3-Cl-4-OCFThree
H i-Pr CFThree              Ph-3-Br-4-OCFThree
H i-Pr CFThree              Ph-3-F-4-OCF2Br
H i-Pr CFThree              Ph-3-Cl-4-OCF2Br
H i-Pr CFThree              Ph-3-Br-4-OCF2Br
H i-Pr CFThree              Ph-3-F-4-OCF2CHF2
H i-Pr CFThree              Ph-3-Cl-4-OCF2CHF2
H i-Pr CFThree              Ph-3-Br-4-OCF2CHF2
H i-Pr CFThree              Ph-3-F-4-OCF2CHFCl
H i-Pr CFThree              Ph-3-Cl-4-OCF2CHFCl
H i-Pr CFThree              Ph-3-Br-4-OCF2CHFCl
H i-Pr CFThree              Ph-3-F-4-OCF2CHFCFThree
H i-Pr CFThree              Ph-3-Cl-4-OCF2CHFCFThree
H i-Pr CFThree              Ph-3-Br-4-OCF2CHFCFThree
H i-Pr CFThree              Ph-3-F-4-OCF2CHFOCFThree
H i-Pr CFThree              Ph-3-Cl-4-OCF2CHFOCFThree
H i-Pr CFThree              Ph-3-Br-4-OCF2CHFOCFThree
H i-Pr CFThree              Ph-3-CHThree-4-OCF2CHFOCFThree
H i-Pr CFThree         Ph-3-F-4-OCF2CHFOCF2CF2CFThree
H i-Pr CFThree         Ph-3-Cl-4-OCF2CHFOCF2CF2CFThree
H i-Pr CFThree         Ph-3-Br-4-OCF2CHFOCF2CF2CFThree
H i-Pr CFThree              Ph (-3-OCF2O-4-)
H i-Pr CFThree              Ph (-3-OCF2CF2O-4-)
H i-Pr CFThree              Ph-3-OPh-4-F
H i-Pr CFThree              Ph-3-NO2-4-F
H i-Pr CFThree              Ph-3-NO2-4-Cl
H i-Pr CFThree              Ph-3-CN-4-F
H i-Pr CFThree              Ph-2,3,4-FThree
H i-Pr CFThree              Ph-2,4,5-FThree
H i-Pr CFThree              Ph-3,4,5-FThree
H i-Pr CFThree              Ph-2,3-F2-4-CHThree
H i-Pr CFThree              Ph-2,3-F2-4-CFThree
H i-Pr CFThree              Ph-3,4-F2-5-CFThree
H i-Pr CFThree              Ph-2-F-3-Cl-5-CFThree
H i-Pr CFThree              Ph-3,5-Cl2-4-OCHThree
H i-Pr CFThree              1-Naph
H i-Pr CFThree              2-Naph
H i-Pr CFThree              L-1a
H i-Pr CFThree             (L-1b) Br
H i-Pr CFThree             (L-1c) Cl
H i-Pr CFThree             (L-1c) Br
H i-Pr CFThree             (L-1c) I
H i-Pr CFThree             (L-1c) CFThree
H i-Pr CFThree             (L-1c) SCHThree
H i-Pr CFThree             (L-1c) SO2CHThree
H i-Pr CFThree             (L-1c) NO2
H i-Pr CFThree              L-2a
H i-Pr CFThree             (L-2b) Br
H i-Pr CFThree              L-3a
H i-Pr CFThree             (L-3b) Cl
H i-Pr CFThree             (L-3b) Br
H i-Pr CFThree             (L-3b) SCHThree
H i-Pr CFThree             (L-3b) SO2CHThree
H i-Pr CFThree             (L-3c) F
H i-Pr CFThree             (L-3c) Cl
H i-Pr CFThree             (L-3c) Br
H i-Pr CFThree             (L-3c) I
H i-Pr CFThree             (L-3c) CFThree
H i-Pr CFThree             (L-3c) SCHThree
H i-Pr CFThree             (L-3c) SO2CHThree
H i-Pr CFThree             (L-3c) NO2
H i-Pr CFThree             (L-3c) CN
H i-Pr CFThree              L-3d
H i-Pr CFThree              L-4a
H i-Pr CFThree             (L-4b) Cl
H i-Pr CFThree             (L-4b) Br
H i-Pr CFThree             (L-4b) NO2
H i-Pr CFThree             (L-4b) CN
H i-Pr CFThree             (L-6a) Cl
H i-Pr CFThree             (L-6a) Br
H i-Pr CFThree             (L-6b) Cl
H i-Pr CFThree             (L-6b) Br
H i-Pr CFThree             (L-6b) NO2
H i-Pr CFThree              L-8a
H i-Pr CFThree              L-10a
H i-Pr CFThree             (L-10b) Cl
H i-Pr CFThree             (L-10b) Br
H i-Pr CFThree             (L-10b) SCHThree
H i-Pr CFThree              L-11a
H i-Pr CFThree             (L-15a) CHF2
H i-Pr CFThree             (L-15b) CFThree
H i-Pr CFThree             (L-16a) CHF2
H i-Pr CFThree             (L-16a) CF2Br
H i-Pr CFThree             (L-17a) Cl
H i-Pr CFThree              L-19a
H i-Pr CFThree              L-20a
H i-Pr CFThree              L-21a
H i-Pr CFThree             (L-21b) Cl
H i-Pr CFThree             (L-21b) Br
H i-Pr CFThree             (L-21b) I
H i-Pr CFThree             (L-21b) CFThree
H i-Pr CFThree             (L-21b) NO2
H i-Pr CFThree              L-22a
H i-Pr CFThree             (L-22b) Cl
H i-Pr CFThree             (L-22b) CFThree
H i-Pr CFThree             (L-22b) SCHThree
H i-Pr CFThree              L-23a
H i-Pr CFThree             (L-23b) Cl
H i-Pr CFThree             (L-23b) Br
H i-Pr CFThree             (L-23b) SCHThree
H i-Pr CFThree             (L-23b) NO2
H i-Pr CFThree             (L-23c) Cl
H i-Pr CFThree             (L-23c) Br
H i-Pr CFThree             (L-23c) SCHThree
H i-Pr CFThree             (L-25a) Cl
H i-Pr CFThree             (L-25a) Br
H i-Pr CFThree             (L-25a) I
H i-Pr CFThree             (L-25a) CFThree
H i-Pr CFThree              L-25b
H i-Pr CFThree             (L-30a) SCHThree
H i-Pr CFThree             (L-31a) Cl
H i-Pr CFThree             (L-31a) Br
H i-Pr CFThree             (L-31a) SCHThree
H i-Pr CFThree             (L-34a) Ph
H i-Pr CFThree             (L-35a) Ph
H i-Pr CFThree             (L-38a) Cl
H i-Pr CFThree             (L-38a) Br
H i-Pr CFThree             (L-38a) NO2
H i-Pr CFThree              L-45a
H i-Pr CFThree             (L-45b) Cl
H i-Pr CFThree             (L-45c) F
H i-Pr CFThree             (L-45c) Cl
H i-Pr CFThree             (L-45c) Br
H i-Pr CFThree             (L-45c) I
H i-Pr CFThree             (L-45c) CFThree
H i-Pr CFThree             (L-45c) NO2
H i-Pr CFThree             (L-45d) F
H i-Pr CFThree             (L-45d) Cl
H i-Pr CFThree             (L-45d) Br
H i-Pr CFThree              L-45e
H i-Pr CFThree              L-45f
H i-Pr CFThree              L-46a
H i-Pr CFThree             (L-46b) Br
H i-Pr CFThree             (L-46c) F
H i-Pr CFThree             (L-46c) Cl
H i-Pr CFThree             (L-46c) Br
H i-Pr CFThree             (L-46c) I
H i-Pr CFThree             (L-46c) CFThree
H i-Pr CFThree             (L-46c) CH2SCHThree
H i-Pr CFThree             (L-46c) CH2SO2CHThree
H i-Pr CFThree             (L-46c) OCH2CFThree
H i-Pr CFThree             (L-46c) OCH (CFThree)2
H i-Pr CFThree             (L-46c) OSO2CHThree
H i-Pr CFThree             (L-46c) SCHThree
H i-Pr CFThree             (L-46c) SO2CHThree
H i-Pr CFThree             (L-46c) SEt
H i-Pr CFThree             (L-46c) SPr-i
H i-Pr CFThree             (L-46c) CN
H i-Pr CFThree              L-46d
H i-Pr CFThree              L-47a
H i-Pr CFThree             (L-47b) F
H i-Pr CFThree             (L-47b) Cl
H i-Pr CFThree              L-47c
H i-Pr CFThree              L-47d
H i-Pr CFThree              L-48a
H i-Pr CFThree             (L-48b) Br
H i-Pr CFThree              L-50a
H i-Pr CFThree             (L-50b) Cl
H i-Pr CFThree             (L-50b) Br
H i-Pr CFThree             (L-50b) I
H i-Pr CFThree             (L-50b) SCHThree
H i-Pr CFThree             (L-50b) SO2CHThree
H i-Pr CFThree              L-51a
H i-Pr CFThree             (L-51b) Cl
H i-Pr CFThree             (L-51b) SCHThree
H i-Pr CFThree              L-53a
H i-Pr CFThree              L-55a
H i-Pr CF2Cl CF2O (Ph-4-Cl)
H i-Pr CF2Cl CH = CH (Ph-4-Cl)
H i-Pr CF2Cl CH = CH (Ph-4-OCFThree)
H i-Pr CF2Cl CH = CH (Ph-3,4-Cl2)
H i-Pr CF2Cl Ph-4-F
H i-Pr CF2Cl Ph-4-Cl
H i-Pr CF2Cl Ph-4-Br
H i-Pr CF2Cl Ph-4-I
H i-Pr CF2Cl Ph-4-CFThree
H i-Pr CF2Cl Ph-4-OCHF2
H i-Pr CF2Cl Ph-4-OCFThree
H i-Pr CF2Cl Ph-4-OCF2Br
H i-Pr CF2Cl Ph-4-OCF2CHF2
H i-Pr CF2Cl Ph-4-OCF2CHFCl
H i-Pr CF2Cl Ph-4-OCF2CHFCFThree
H i-Pr CF2Cl Ph-4-OCF2CHFOCFThree
H i-Pr CF2Cl Ph-4-OCF2CHFOCF2CF2CFThree
H i-Pr CF2Cl Ph-4-O (L-45g)
H i-Pr CF2Cl Ph-3,4-Cl2
H i-Pr CF2Cl Ph (-3-OCF2O-4-)
H i-Pr CF2Cl Ph (-3-OCF2CF2O-4-)
H i-Pr CF2Cl (L-45c) Cl
H i-Pr CF2Cl (L-45c) Br
H i-Pr CF2Cl (L-45c) CFThree
H i-Pr CF2Cl L-45e
H i-Pr CF2Cl L-45f
H i-Pr CF2Cl (L-46c) Cl
H i-Pr CF2Cl (L-46c) Br
H i-Pr CF2Cl (L-46c) CFThree
H i-Pr CF2Cl L-46d
H i-Pr CFCl2            Ph-4-CFThree
H i-Pr CF2Br CF2O (Ph-4-Cl)
H i-Pr CF2Br CH = CH (Ph-4-Cl)
H i-Pr CF2Br CH = CH (Ph-4-OCFThree)
H i-Pr CF2Br CH = CH (Ph-3,4-Cl2)
H i-Pr CF2Br Ph-4-F
H i-Pr CF2Br Ph-4-Cl
H i-Pr CF2Br Ph-4-Br
H i-Pr CF2Br Ph-4-I
H i-Pr CF2Br Ph-4-CFThree
H i-Pr CF2Br Ph-4-OCHF2
H i-Pr CF2Br Ph-4-OCFThree
H i-Pr CF2Br Ph-4-OCF2Br
H i-Pr CF2Br Ph-4-OCF2CHF2
H i-Pr CF2Br Ph-4-OCF2CHFCl
H i-Pr CF2Br Ph-4-OCF2CHFCFThree
H i-Pr CF2Br Ph-4-OCF2CHFOCFThree
H i-Pr CF2Br Ph-4-OCF2CHFOCF2CF2CFThree
H i-Pr CF2Br Ph-4-O (L-45g)
H i-Pr CF2Br Ph-3,4-Cl2
H i-Pr CF2Br Ph (-3-OCF2O-4-)
H i-Pr CF2Br Ph (-3-OCF2CF2O-4-)
H i-Pr CF2Br (L-45c) Cl
H i-Pr CF2Br (L-45c) Br
H i-Pr CF2Br (L-45c) CFThree
H i-Pr CF2Br L-45e
H i-Pr CF2Br L-45f
H i-Pr CF2Br (L-46c) Cl
H i-Pr CF2Br (L-46c) Br
H i-Pr CF2Br (L-46c) CFThree
H i-Pr CF2Br L-46d
H i-Pr CFClBr Ph-4-OCFThree
H i-Pr CFBr2           (L-45c) CFThree
H i-Pr CF2CHF2          Ph-4-Br
H i-Pr CF2CFThree           CF2O (Ph-4-Cl)
H i-Pr CF2CFThree           CH = CH (Ph-4-Cl)
H i-Pr CF2CFThree           CH = CH (Ph-4-OCFThree)
H i-Pr CF2CFThree           CH = CH (Ph-3,4-Cl2)
H i-Pr CF2CFThree           Ph-4-F
H i-Pr CF2CFThree           Ph-4-Cl
H i-Pr CF2CFThree           Ph-4-Br
H i-Pr CF2CFThree           Ph-4-I
H i-Pr CF2CFThree           Ph-4-CFThree
H i-Pr CF2CFThree           Ph-4-OCHF2
H i-Pr CF2CFThree           Ph-4-OCFThree
H i-Pr CF2CFThree           Ph-4-OCF2Br
H i-Pr CF2CFThree           Ph-4-OCF2CHF2
H i-Pr CF2CFThree           Ph-4-OCF2CHFCl
H i-Pr CF2CFThree           Ph-4-OCF2CHFCFThree
H i-Pr CF2CFThree           Ph-4-OCF2CHFOCFThree
H i-Pr CF2CFThree           Ph-4-OCF2CHFOCF2CF2CFThree
H i-Pr CF2CFThree           Ph-4-O (L-45g)
H i-Pr CF2CFThree           Ph-3,4-Cl2
H i-Pr CF2CFThree           Ph (-3-OCF2O-4-)
H i-Pr CF2CFThree           Ph (-3-OCF2CF2O-4-)
H i-Pr CF2CFThree          (L-45c) Cl
H i-Pr CF2CFThree          (L-45c) Br
H i-Pr CF2CFThree          (L-45c) CFThree
H i-Pr CF2CFThree           L-45e
H i-Pr CF2CFThree           L-45f
H i-Pr CF2CFThree          (L-46c) Cl
H i-Pr CF2CFThree          (L-46c) Br
H i-Pr CF2CFThree          (L-46c) CFThree
H i-Pr CF2CFThree           L-46d
H i-Pr CF2CF2Cl Ph-4-CFThree
H i-Pr CFClCFThree          Ph-4-OCFThree
H i-Pr CFClCF2Cl (L-45c) CFThree
H i-Pr CF2CF2Br Ph-4-Br
H i-Pr CFBrCFThree          Ph-4-CFThree
H i-Pr CF2CHFCFThree        Ph-4-OCFThree
H i-Pr CF2CF2CFThree        CF2O (Ph-4-Cl)
H i-Pr CF2CF2CFThree        CH = CH (Ph-4-Cl)
H i-Pr CF2CF2CFThree        CH = CH (Ph-4-OCFThree)
H i-Pr CF2CF2CFThree        CH = CH (Ph-3,4-Cl2)
H i-Pr CF2CF2CFThree        Ph-4-F
H i-Pr CF2CF2CFThree        Ph-4-Cl
H i-Pr CF2CF2CFThree        Ph-4-Br
H i-Pr CF2CF2CFThree        Ph-4-I
H i-Pr CF2CF2CFThree        Ph-4-CFThree
H i-Pr CF2CF2CFThree        Ph-4-OCHF2
H i-Pr CF2CF2CFThree        Ph-4-OCFThree
H i-Pr CF2CF2CFThree        Ph-4-OCF2Br
H i-Pr CF2CF2CFThree        Ph-4-OCF2CHF2
H i-Pr CF2CF2CFThree        Ph-4-OCF2CHFCl
H i-Pr CF2CF2CFThree        Ph-4-OCF2CHFCFThree
H i-Pr CF2CF2CFThree        Ph-4-OCF2CHFOCFThree
H i-Pr CF2CF2CFThree        Ph-4-OCF2CHFOCF2CF2CFThree
H i-Pr CF2CF2CFThree        Ph-4-O (L-45g)
H i-Pr CF2CF2CFThree        Ph-3,4-Cl2
H i-Pr CF2CF2CFThree        Ph (-3-OCF2O-4-)
H i-Pr CF2CF2CFThree        Ph (-3-OCF2CF2O-4-)
H i-Pr CF2CF2CFThree       (L-45c) Cl
H i-Pr CF2CF2CFThree       (L-45c) Br
H i-Pr CF2CF2CFThree       (L-45c) CFThree
H i-Pr CF2CF2CFThree        L-45e
H i-Pr CF2CF2CFThree        L-45f
H i-Pr CF2CF2CFThree       (L-46c) Cl
H i-Pr CF2CF2CFThree       (L-46c) Br
H i-Pr CF2CF2CFThree       (L-46c) CFThree
H i-Pr CF2CF2CFThree        L-46d
H i-Pr CF (CFThree)2        (L-45c) CFThree
H i-Pr CF2CFClCF2Cl Ph-4-Br
H i-Pr CF2CFBrCF2Cl Ph-4-CFThree
H i-Pr CF2CF2CF2CHF2    Ph-4-OCFThree
H i-Pr CF2CF2CF2CFThree    (L-45c) CFThree
H i-Pr CF (CFThreeCF2CFThree    Ph-4-Br
H i-Pr CF2CF2CF2CF2Cl Ph-4-CFThree
H i-Pr CF2CF2CF2CF2CF2CFThree      Ph-4-OCFThree
H i-Pr T-1 (L-45c) CFThree
H i-Pr T-2 Ph-4-Br
H i-Pr CH2OCHThree          Ph-4-CFThree
H i-Pr CH2OEt Ph-4-OCFThree
H i-Pr CH2OCH2CFThree      (L-45c) CFThree
H i-Pr CH2OCH (CFThree)2     Ph-4-Br
H i-Pr CF2OCHThree          CF2O (Ph-4-Cl)
H i-Pr CF2OCHThree          CH = CH (Ph-4-Cl)
H i-Pr CF2OCHThree          CH = CH (Ph-4-OCFThree)
H i-Pr CF2OCHThree          CH = CH (Ph-3,4-Cl2)
H i-Pr CF2OCHThree          Ph-4-F
H i-Pr CF2OCHThree          Ph-4-Cl
H i-Pr CF2OCHThree          Ph-4-Br
H i-Pr CF2OCHThree          Ph-4-I
H i-Pr CF2OCHThree          Ph-4-CFThree
H i-Pr CF2OCHThree          Ph-4-OCHF2
H i-Pr CF2OCHThree          Ph-4-OCFThree
H i-Pr CF2OCHThree          Ph-4-OCF2Br
H i-Pr CF2OCHThree          Ph-4-OCF2CHF2
H i-Pr CF2OCHThree          Ph-4-OCF2CHFCl
H i-Pr CF2OCHThree          Ph-4-OCF2CHFCFThree
H i-Pr CF2OCHThree          Ph-4-OCF2CHFOCFThree
H i-Pr CF2OCHThree          Ph-4-OCF2CHFOCF2CF2CFThree
H i-Pr CF2OCHThree          Ph-4-O (L-45g)
H i-Pr CF2OCHThree          Ph-3,4-Cl2
H i-Pr CF2OCHThree          Ph (-3-OCF2O-4-)
H i-Pr CF2OCHThree          Ph (-3-OCF2CF2O-4-)
H i-Pr CF2OCHThree         (L-45c) Cl
H i-Pr CF2OCHThree         (L-45c) Br
H i-Pr CF2OCHThree         (L-45c) CFThree
H i-Pr CF2OCHThree          L-45e
H i-Pr CF2OCHThree          L-45f
H i-Pr CF2OCHThree         (L-46c) Cl
H i-Pr CF2OCHThree         (L-46c) Br
H i-Pr CF2OCHThree         (L-46c) CFThree
H i-Pr CF2OCHThree          L-46d
H i-Pr CF2OCF2CF2CFThree         Ph-4-CFThree
H i-Pr CF2OCF2CF2OCFThree        Ph-4-OCFThree
H i-Pr CF (CFThree) OCHThree          (L-45c) CFThree
H i-Pr CF (CFThreeOCF2CF2CFThree     Ph-4-Br
H i-Pr CH2SCHThree          Ph-4-CFThree
H i-Pr CH2SO2CHThree        Ph-4-OCFThree
H i-Pr CH2SEt (L-45c) CFThree
H i-Pr CH2SCFThree          Ph-4-Br
H i-Pr CH2SPh Ph-4-CFThree
H i-Pr CH2CH2SCHThree       Ph-4-OCFThree
H i-Pr CH2CH2SCFThree      (L-45c) CFThree
H i-Pr CF2SCHThree          CF2O (Ph-4-Cl)
H i-Pr CF2SCHThree          CH = CH (Ph-4-Cl)
H i-Pr CF2SCHThree          CH = CH (Ph-4-OCFThree)
H i-Pr CF2SCHThree          CH = CH (Ph-3,4-Cl2)
H i-Pr CF2SCHThree          Ph-4-F
H i-Pr CF2SCHThree          Ph-4-Cl
H i-Pr CF2SCHThree          Ph-4-Br
H i-Pr CF2SCHThree          Ph-4-I
H i-Pr CF2SCHThree          Ph-4-CFThree
H i-Pr CF2SCHThree          Ph-4-OCHF2
H i-Pr CF2SCHThree          Ph-4-OCFThree
H i-Pr CF2SCHThree          Ph-4-OCF2Br
H i-Pr CF2SCHThree          Ph-4-OCF2CHF2
H i-Pr CF2SCHThree          Ph-4-OCF2CHFCl
H i-Pr CF2SCHThree          Ph-4-OCF2CHFCFThree
H i-Pr CF2SCHThree          Ph-4-OCF2CHFOCFThree
H i-Pr CF2SCHThree          Ph-4-OCF2CHFOCF2CF2CFThree
H i-Pr CF2SCHThree          Ph-4-O (L-45g)
H i-Pr CF2SCHThree          Ph-3,4-Cl2
H i-Pr CF2SCHThree          Ph (-3-OCF2O-4-)
H i-Pr CF2SCHThree          Ph (-3-OCF2CF2O-4-)
H i-Pr CF2SCHThree         (L-45c) Cl
H i-Pr CF2SCHThree         (L-45c) Br
H i-Pr CF2SCHThree         (L-45c) CFThree
H i-Pr CF2SCHThree          L-45e
H i-Pr CF2SCHThree          L-45f
H i-Pr CF2SCHThree         (L-46c) Cl
H i-Pr CF2SCHThree         (L-46c) Br
H i-Pr CF2SCHThree         (L-46c) CFThree
H i-Pr CF2SCHThree          L-46d
H i-Pr CF2SEt Ph-4-Br
H i-Pr CF2SPr-n Ph-4-CFThree
H i-Pr CF2SPr-i Ph-4-OCFThree
H i-Pr CF2SCH2Ph (L-45c) CFThree
H i-Pr CF2SPh Ph-4-Br
H i-Pr CF2C (O) OEt Ph-4-CFThree
H i-Pr CF2SO2N (CHThree)2    Ph-4-OCFThree
H i-Pr CN (L-45c) CFThree
H i-Pr C (O) OCHThree         Ph-4-Br
H i-Pr C (O) OEt Ph-4-CFThree
H i-Pr C (O) OPr-n Ph-4-OCFThree
H i-Pr C (O) OPr-i (L-45c) CFThree
H i-Pr C (O) OBu-n Ph-4-Br
H i-Pr C (O) OBu-t Ph-4-CFThree
H i-Pr C (O) SEt Ph-4-OCFThree
H i-Pr C (O) NH2         (L-45c) CFThree
H i-Pr C (S) NH2          Ph-4-Br
H i-Pr C (CHThree) = NOCHThree     Ph-4-CFThree
H i-Pr Ph Ph-4-OCFThree
H i-Pr Ph-4-F (L-45c) CFThree
H i-Pr Ph-4-Cl Ph-4-Br
H i-Pr Ph-4-CFThree         Ph-4-CFThree
H i-Pr Ph-4-OCFThree        Ph-4-OCFThree
CHThree       i-Pr CFThree              Ph-4-Br
CHThree       i-Pr CFThree              Ph-4-CFThree
CHThree       i-Pr CFThree              Ph-4-OCFThree
CHThree       i-Pr CFThree             (L-45c) CFThree
Et i-Pr CFThree             (L-45c) CFThree
i-Pr i-Pr CFThree              Ph-4-Br
CH2OCHThree   i-Pr CFThree              Ph-4-CFThree
CH2OEt i-Pr CFThree              Ph-4-OCFThree
H c-Pr CFThree              CF2O (Ph-4-Cl)
H c-Pr CFThree              CH = CH (Ph-4-Cl)
H c-Pr CFThree              CH = CH (Ph-4-OCFThree)
H c-Pr CFThree              CH = CH (Ph-3,4-Cl2)
H c-Pr CFThree              Ph-4-F
H c-Pr CFThree              Ph-4-Cl
H c-Pr CFThree              Ph-4-Br
H c-Pr CFThree              Ph-4-I
H c-Pr CFThree              Ph-4-CFThree
H c-Pr CFThree              Ph-4-OCHF2
H c-Pr CFThree              Ph-4-OCFThree
H c-Pr CFThree              Ph-4-OCF2Br
H c-Pr CFThree              Ph-4-OCF2CHF2
H c-Pr CFThree              Ph-4-OCF2CHFCl
H c-Pr CFThree              Ph-4-OCF2CHFCFThree
H c-Pr CFThree              Ph-4-OCF2CHFOCFThree
H c-Pr CFThree              Ph-4-OCF2CHFOCF2CF2CFThree
H c-Pr CFThree              Ph-4-O (L-45g)
H c-Pr CFThree              Ph-3,4-Cl2
H c-Pr CFThree              Ph (-3-OCF2O-4-)
H c-Pr CFThree              Ph (-3-OCF2CF2O-4-)
H c-Pr CFThree             (L-45c) Cl
H c-Pr CFThree             (L-45c) Br
H c-Pr CFThree             (L-45c) CFThree
H c-Pr CFThree              L-45e
H c-Pr CFThree              L-45f
H c-Pr CFThree             (L-46c) Cl
H c-Pr CFThree             (L-46c) Br
H c-Pr CFThree             (L-46c) CFThree
H c-Pr CFThree              L-46d
H n-Bu CFThree              CH = CH (Ph-4-Cl)
H n-Bu CFThree              Ph-4-Cl
H n-Bu CFThree              Ph-4-Br
H n-Bu CFThree              Ph-4-CFThree
H n-Bu CFThree              Ph-4-OCFThree
H n-Bu CFThree              Ph-4-OCF2Br
H n-Bu CFThree              Ph-4-OCF2CHFCFThree
H n-Bu CFThree              Ph-4-OCF2CHFOCFThree
H n-Bu CFThree              Ph-4-OCF2CHFOCF2CF2CFThree
H n-Bu CFThree              Ph-4-O (L-45g)
H n-Bu CFThree              Ph-3,4-Cl2
H n-Bu CFThree              Ph (-3-OCF2O-4-)
H n-Bu CFThree              Ph (-3-OCF2CF2O-4-)
H n-Bu CFThree             (L-45c) CFThree
H n-Bu CFThree              L-45f
H n-Bu CFThree             (L-46c) CFThree
H n-Bu CFThree              L-46d
H i-Bu CFThree             (L-45c) CFThree
CHThree       i-Bu CFThree              Ph-4-Br
H CH2Pr-c CFThree              Ph-4-CFThree
H s-Bu CHThree              Ph-4-Br
H s-Bu CHThree              Ph-4-CFThree
H s-Bu CHThree              Ph-4-OCFThree
H s-Bu CHThree             (L-45c) Cl
H s-Bu CHThree             (L-45c) Br
H s-Bu CHThree             (L-45c) CFThree
H s-Bu Et Ph-4-OCFThree
H s-Bu n-Pr (L-45c) CFThree
H s-Bu i-Pr Ph-4-Br
H s-Bu c-Pr Ph-4-CFThree
H s-Bu CHF2             Ph-4-OCFThree
H s-Bu CFThree              CF2O (Ph-4-Cl)
H s-Bu CFThree              CH = CH (Ph-4-Cl)
H s-Bu CFThree              CH = CH (Ph-4-OCFThree)
H s-Bu CFThree              CH = CH (Ph-3,4-Cl2)
H s-Bu CFThree              Ph-4-F
H s-Bu CFThree              Ph-4-Cl
H s-Bu CFThree              Ph-4-Br
H s-Bu CFThree              Ph-4-I
H s-Bu CFThree              Ph-4-CFThree
H s-Bu CFThree              Ph-4-OCHF2
H s-Bu CFThree              Ph-4-OCFThree
H s-Bu CFThree              Ph-4-OCF2Br
H s-Bu CFThree              Ph-4-OCF2CHF2
H s-Bu CFThree              Ph-4-OCF2CHFCl
H s-Bu CFThree              Ph-4-OCF2CHFCFThree
H s-Bu CFThree              Ph-4-OCF2CHFOCFThree
H s-Bu CFThree              Ph-4-OCF2CHFOCF2CF2CFThree
H s-Bu CFThree              Ph-4-O (L-45g)
H s-Bu CFThree              Ph-3,4-Cl2
H s-Bu CFThree              Ph (-3-OCF2O-4-)
H s-Bu CFThree              Ph (-3-OCF2CF2O-4-)
H s-Bu CFThree             (L-45c) Cl
H s-Bu CFThree             (L-45c) Br
H s-Bu CFThree             (L-45c) CFThree
H s-Bu CFThree              L-45e
H s-Bu CFThree              L-45f
H s-Bu CFThree             (L-46c) Cl
H s-Bu CFThree             (L-46c) Br
H s-Bu CFThree             (L-46c) CFThree
H s-Bu CFThree              L-46d
H s-Bu CF2Cl (L-45c) CFThree
H s-Bu CF2Br Ph-4-Br
H s-Bu CF2CFThree           Ph-4-CFThree
H s-Bu CF2CF2CFThree        Ph-4-OCFThree
H s-Bu CF2OCHThree         (L-45c) CFThree
H s-Bu CF2SCHThree          Ph-4-Br
H t-Bu CHThree              Ph-4-Br
H t-Bu CHThree              Ph-4-CFThree
H t-Bu CHThree              Ph-4-OCFThree
H t-Bu CHThree             (L-45c) Cl
H t-Bu CHThree             (L-45c) Br
H t-Bu CHThree             (L-45c) CFThree
H t-Bu Et Ph-4-CFThree
H t-Bu n-Pr Ph-4-OCFThree
H t-Bu i-Pr (L-45c) CFThree
H t-Bu c-Pr Ph-4-Br
H t-Bu CHF2             Ph-4-CFThree
H t-Bu CFThree              CF2O (Ph-4-Cl)
H t-Bu CFThree              CH = CH (Ph-4-Cl)
H t-Bu CFThree              CH = CH (Ph-4-OCFThree)
H t-Bu CFThree              CH = CH (Ph-3,4-Cl2)
H t-Bu CFThree              Ph-4-F
H t-Bu CFThree              Ph-4-Cl
H t-Bu CFThree              Ph-4-Br
H t-Bu CFThree              Ph-4-I
H t-Bu CFThree              Ph-4-CFThree
H t-Bu CFThree              Ph-4-OCHF2
H t-Bu CFThree              Ph-4-OCFThree
H t-Bu CFThree              Ph-4-OCF2Br
H t-Bu CFThree              Ph-4-OCF2CHF2
H t-Bu CFThree              Ph-4-OCF2CHFCl
H t-Bu CFThree              Ph-4-OCF2CHFCFThree
H t-Bu CFThree              Ph-4-OCF2CHFOCFThree
H t-Bu CFThree              Ph-4-OCF2CHFOCF2CF2CFThree
H t-Bu CFThree              Ph-4-O (L-45g)
H t-Bu CFThree              Ph-3,4-Cl2
H t-Bu CFThree              Ph (-3-OCF2O-4-)
H t-Bu CFThree              Ph (-3-OCF2CF2O-4-)
H t-Bu CFThree             (L-45c) Cl
H t-Bu CFThree             (L-45c) Br
H t-Bu CFThree             (L-45c) CFThree
H t-Bu CFThree              L-45e
H t-Bu CFThree              L-45f
H t-Bu CFThree             (L-46c) Cl
H t-Bu CFThree             (L-46c) Br
H t-Bu CFThree             (L-46c) CFThree
H t-Bu CFThree              L-46d
H t-Bu CF2Cl Ph-4-OCFThree
H t-Bu CF2Br (L-45c) CFThree
H t-Bu CF2CFThree           Ph-4-Br
H t-Bu CF2CF2CFThree        Ph-4-CFThree
H t-Bu CF2OCHThree          Ph-4-OCFThree
H t-Bu CF2SCHThree         (L-45c) CFThree
H c-Bu CFThree              Ph-4-Br
H n-Pen CFThree              Ph-4-CFThree
H CH2CH2Pr-i CFThree              Ph-4-OCFThree
H CH2CH (CHThree) Et CFThree             (L-45c) CFThree
H CH2Bu-t CFThree              Ph-4-Br
H CH (CHThree) Pr-n CFThree              CF2O (Ph-4-Cl)
H CH (CHThree) Pr-n CFThree              CH = CH (Ph-4-Cl)
H CH (CHThree) Pr-n CFThree              CH = CH (Ph-4-OCFThree)
H CH (CHThree) Pr-n CFThree              CH = CH (Ph-3,4-Cl2)
H CH (CHThree) Pr-n CFThree              Ph-4-F
H CH (CHThree) Pr-n CFThree              Ph-4-Cl
H CH (CHThree) Pr-n CFThree              Ph-4-Br
H CH (CHThree) Pr-n CFThree              Ph-4-I
H CH (CHThree) Pr-n CFThree              Ph-4-CFThree
H CH (CHThree) Pr-n CFThree              Ph-4-OCHF2
H CH (CHThree) Pr-n CFThree              Ph-4-OCFThree
H CH (CHThree) Pr-n CFThree              Ph-4-OCF2Br
H CH (CHThree) Pr-n CFThree              Ph-4-OCF2CHF2
H CH (CHThree) Pr-n CFThree              Ph-4-OCF2CHFCl
H CH (CHThree) Pr-n CFThree              Ph-4-OCF2CHFCFThree
H CH (CHThree) Pr-n CFThree              Ph-4-OCF2CHFOCFThree
H CH (CHThree) Pr-n CFThree              Ph-4-OCF2CHFOCF2CF2CFThree
H CH (CHThree) Pr-n CFThree              Ph-4-O (L-45g)
H CH (CHThree) Pr-n CFThree              Ph-3,4-Cl2
H CH (CHThree) Pr-n CFThree              Ph (-3-OCF2O-4-)
H CH (CHThree) Pr-n CFThree              Ph (-3-OCF2CF2O-4-)
H CH (CHThree) Pr-n CFThree             (L-45c) Cl
H CH (CHThree) Pr-n CFThree             (L-45c) Br
H CH (CHThree) Pr-n CFThree             (L-45c) CFThree
H CH (CHThree) Pr-n CFThree              L-45e
H CH (CHThree) Pr-n CFThree              L-45f
H CH (CHThree) Pr-n CFThree             (L-46c) Cl
H CH (CHThree) Pr-n CFThree             (L-46c) Br
H CH (CHThree) Pr-n CFThree             (L-46c) CFThree
H CH (CHThree) Pr-n CFThree              L-46d
H CH (CHThree) Pr-i CFThree              Ph-4-CFThree
H CH (Et)2                      CFThree              Ph-4-OCFThree
H C (CHThree)2Et CFThree              Ph-4-Br
H C (CHThree)2Et CFThree              Ph-4-CFThree
H C (CHThree)2Et CFThree              Ph-4-OCFThree
H C (CHThree)2Et CFThree             (L-45c) CFThree
H c-Pen CFThree             (L-45c) CFThree
H n-Hex CFThree              Ph-4-Br
H CH (CHThree) Bu-i CFThree              Ph-4-CFThree
H C (CHThree)2Pr-n CFThree              Ph-4-Br
H C (CHThree)2Pr-n CFThree              Ph-4-CFThree
H C (CHThree)2Pr-n CFThree              Ph-4-OCFThree
H C (CHThree)2Pr-n CFThree             (L-45c) CFThree
H c-Hex CFThree              Ph-4-OCFThree
H CH2Hex-c CFThree             (L-45c) CFThree
H Oct CFThree              Ph-4-Br
H C (CHThree)2CH2Bu-t CFThree              Ph-4-CFThree
 -CH2CH2CH2CH2-CFThree              Ph-4-OCFThree
 -CH2CH2CH2CH2CH2-CFThree             (L-45c) CFThree
 -CH2CH2CH (CHThree) CH2CH2-CFThree              Ph-4-Br
 -CH2CH (CHThree) CH2CH (CHThree) CH2-CFThree              Ph-4-CFThree
 -CH2CH2CH2CH2CH2CH2-CFThree              Ph-4-OCFThree
H CH2CH2F CFThree             (L-45c) CFThree
H CH2CH2Cl CFThree              Ph-4-Br
H CH2CFThree                       CFThree              Ph-4-CFThree
H CH (CHThree) CH2F CFThree              Ph-4-Br
H CH (CHThree) CH2F CFThree              Ph-4-CFThree
H CH (CHThree) CH2F (S) CFThree              Ph-4-CFThree
H CH (CHThree) CH2F CFThree              Ph-4-OCFThree
H CH (CHThree) CH2F CFThree             (L-45c) CFThree
H CH (CHThree) CH2Cl CFThree              Ph-4-Br
H CH (CHThree) CH2Cl CFThree              Ph-4-CFThree
H CH (CHThree) CH2Cl CFThree              Ph-4-OCFThree
H CH (CHThree) CH2Cl CFThree             (L-45c) CFThree
H CH (CHThree) CH2Br CFThree              Ph-4-OCFThree
H CH (CHThree) CH2Br (R) CFThree              Ph-4-OCFThree
H CH (CHThree) CH2Br (S) CFThree              Ph-4-OCFThree
H C (CHThree)2CH2Cl CFThree              Ph-4-Br
H C (CHThree)2CH2Cl CFThree              Ph-4-CFThree
H C (CHThree)2CH2Cl CFThree              Ph-4-OCFThree
H C (CHThree)2CH2Cl CFThree             (L-45c) CFThree
H C (CHThree)2CH2Br CFThree             (L-45c) CFThree
H C (CHThree)2CHBrCH2Br CFThree              Ph-4-Br
H CH2OCHThree                      CFThree              Ph-4-CFThree
H CH2CH2OCHThree                   CFThree              Ph-4-OCFThree
H CH2CH2OEt CFThree             (L-45c) CFThree
CH2CH2OEt CH2CH2OEt CFThree              Ph-4-Br
H CH2CH2OC (O) NHEt CFThree              Ph-4-CFThree
H CH2CH2OPh CFThree              Ph-4-OCFThree
H CH2CH2O (Ph-2-Cl) CFThree             (L-45c) CFThree
H CH2CH2O (Ph-3-Cl) CFThree              Ph-4-Br
H CH2CH2O (Ph-4-Cl) CFThree              Ph-4-CFThree
H CH2CH (OH) CHThree                 CFThree              Ph-4-OCFThree
H CH2CH (OH) Et CFThree             (L-45c) CFThree
H CH2CH (OH) Ph CFThree              Ph-4-Br
H CH2CH (OH) CH2Ph CFThree              Ph-4-CFThree
H CH2C (CHThree)2OSi (CHThree)Three          CFThree              CH = CH (Ph-4-Cl)
H CH2C (CHThree)2OSi (CHThree)Three          CFThree              Ph-4-Cl
H CH2C (CHThree)2OSi (CHThree)Three          CFThree              Ph-4-Br
H CH2C (CHThree)2OSi (CHThree)Three          CFThree              Ph-4-CFThree
H CH2C (CHThree)2OSi (CHThree)Three          CFThree              Ph-4-OCFThree
H CH2C (CHThree)2OSi (CHThree)Three          CFThree              Ph-4-OCF2Br
H CH2C (CHThree)2OSi (CHThree)Three          CFThree              Ph-4-OCF2CHFCFThree
H CH2C (CHThree)2OSi (CHThree)Three          CFThree              Ph-4-OCF2CHFOCFThree
H CH2C (CHThree)2OSi (CHThree)Three          CFThree              Ph-4-OCF2CHFOCF2CF2CFThree
H CH2C (CHThree)2OSi (CHThree)Three          CFThree              Ph-4-O (L-45g)
H CH2C (CHThree)2OSi (CHThree)Three          CFThree              Ph-3,4-Cl2
H CH2C (CHThree)2OSi (CHThree)Three          CFThree              Ph (-3-OCF2O-4-)
H CH2C (CHThree)2OSi (CHThree)Three          CFThree              Ph (-3-OCF2CF2O-4-)
H CH2C (CHThree)2OSi (CHThree)Three          CFThree             (L-45c) CFThree
H CH2C (CHThree)2OSi (CHThree)Three          CFThree              L-45f
H CH2C (CHThree)2OSi (CHThree)Three          CFThree             (L-46c) CFThree
H CH2C (CHThree)2OSi (CHThree)Three          CFThree              L-46d
H CH2CH (OEt)2                  CFThree              Ph-4-OCFThree
H CH (CHThree) CH2OH CFThree             (L-45c) CFThree
H CH (CHThree) CH2OH (R) CFThree             (L-45c) CFThree
H CH (CHThree) CH2OH (S) CFThree             (L-45c) CFThree
H CH (CHThree) CH2OCHThree               CHThree              Ph-4-Br
H CH (CHThree) CH2OCHThree               CHThree              Ph-4-CFThree
H CH (CHThree) CH2OCHThree               CHThree              Ph-4-OCFThree
H CH (CHThree) CH2OCHThree               CHThree             (L-45c) Cl
H CH (CHThree) CH2OCHThree               CHThree             (L-45c) Br
H CH (CHThree) CH2OCHThree               CHThree             (L-45c) CFThree
H CH (CHThree) CH2OCHThree               Et Ph-4-Br
H CH (CHThree) CH2OCHThree               n-Pr Ph-4-CFThree
H CH (CHThree) CH2OCHThree               i-Pr Ph-4-OCFThree
H CH (CHThree) CH2OCHThree               c-Pr (L-45c) CFThree
H CH (CHThree) CH2OCHThree               CHF2             Ph-4-Br
H CH (CHThree) CH2OCHThree               CFThree              CF2O (Ph-4-Cl)
H CH (CHThree) CH2OCHThree               CFThree              CH = CH (Ph-4-Cl)
H CH (CHThree) CH2OCHThree               CFThree              CH = CH (Ph-4-OCFThree)
H CH (CHThree) CH2OCHThree               CFThree              CH = CH (Ph-3,4-Cl2)
H CH (CHThree) CH2OCHThree               CFThree              Ph-4-F
H CH (CHThree) CH2OCHThree               CFThree              Ph-4-Cl
H CH (CHThree) CH2OCHThree               CFThree              Ph-4-Br
H CH (CHThree) CH2OCHThree               CFThree              Ph-4-I
H CH (CHThree) CH2OCHThree               CFThree              Ph-4-CFThree
H CH (CHThree) CH2OCHThree               CFThree              Ph-4-OCHF2
H CH (CHThree) CH2OCHThree               CFThree              Ph-4-OCFThree
H CH (CHThree) CH2OCHThree               CFThree              Ph-4-OCF2Br
H CH (CHThree) CH2OCHThree               CFThree              Ph-4-OCF2CHF2
H CH (CHThree) CH2OCHThree               CFThree              Ph-4-OCF2CHFCl
H CH (CHThree) CH2OCHThree               CFThree              Ph-4-OCF2CHFCFThree
H CH (CHThree) CH2OCHThree               CFThree              Ph-4-OCF2CHFOCFThree
H CH (CHThree) CH2OCHThree               CFThree              Ph-4-OCF2CHFOCF2CF2CFThree
H CH (CHThree) CH2OCHThree               CFThree              Ph-4-O (L-45g)
H CH (CHThree) CH2OCHThree               CFThree              Ph-3,4-Cl2
H CH (CHThree) CH2OCHThree               CFThree              Ph (-3-OCF2O-4-)
H CH (CHThree) CH2OCHThree               CFThree              Ph (-3-OCF2CF2O-4-)
H CH (CHThree) CH2OCHThree               CFThree             (L-45c) Cl
H CH (CHThree) CH2OCHThree               CFThree             (L-45c) Br
H CH (CHThree) CH2OCHThree               CFThree             (L-45c) CFThree
H CH (CHThree) CH2OCHThree               CFThree              L-45e
H CH (CHThree) CH2OCHThree               CFThree              L-45f
H CH (CHThree) CH2OCHThree               CFThree             (L-46c) Cl
H CH (CHThree) CH2OCHThree               CFThree             (L-46c) Br
H CH (CHThree) CH2OCHThree               CFThree             (L-46c) CFThree
H CH (CHThree) CH2OCHThree               CFThree              L-46d
H CH (CHThree) CH2OCHThree               CF2Cl Ph-4-CFThree
H CH (CHThree) CH2OCHThree               CF2Br Ph-4-OCFThree
H CH (CHThree) CH2OCHThree               CF2CFThree          (L-45c) CFThree
H CH (CHThree) CH2OCHThree               CF2CF2CFThree        Ph-4-Br
H CH (CHThree) CH2OCHThree               CF2OCHThree          Ph-4-CFThree
H CH (CHThree) CH2OCHThree               CF2SCHThree          Ph-4-OCFThree
H CH (CHThree) CH2OEt CFThree             (L-45c) CFThree
H CH (CHThree) CH2OPr-n CFThree              Ph-4-Br
H CH (CHThree) CH2OBu-i CFThree              Ph-4-CFThree
H CH (CHThree) CH2OCH2CH2OCHThree        CFThree              Ph-4-OCFThree
H CH (CHThree) CH2OCH2CH2SCHThree        CFThree             (L-45c) CFThree
H CH (CHThree) CH2OCH2CH2SEt CFThree              Ph-4-Br
H CH (CHThree) CH2OCH2Ph CFThree              Ph-4-CFThree
H CH (CHThree) CH2OC (O) CHThree           CFThree              CH = CH (Ph-4-Cl)
H CH (CHThree) CH2OC (O) CHThree           CFThree              Ph-4-Cl
H CH (CHThree) CH2OC (O) CHThree           CFThree              Ph-4-Br
H CH (CHThree) CH2OC (O) CHThree           CFThree              Ph-4-CFThree
H CH (CHThree) CH2OC (O) CHThree           CFThree              Ph-4-OCFThree
H CH (CHThree) CH2OC (O) CHThree           CFThree              Ph-4-OCF2Br
H CH (CHThree) CH2OC (O) CHThree           CFThree              Ph-4-OCF2CHFCFThree
H CH (CHThree) CH2OC (O) CHThree           CFThree              Ph-4-OCF2CHFOCFThree
H CH (CHThree) CH2OC (O) CHThree           CFThree              Ph-4-OCF2CHFOCF2CF2CFThree
H CH (CHThree) CH2OC (O) CHThree           CFThree              Ph-4-O (L-45g)
H CH (CHThree) CH2OC (O) CHThree           CFThree              Ph-3,4-Cl2
H CH (CHThree) CH2OC (O) CHThree           CFThree              Ph (-3-OCF2O-4-)
H CH (CHThree) CH2OC (O) CHThree           CFThree              Ph (-3-OCF2CF2O-4-)
H CH (CHThree) CH2OC (O) CHThree           CFThree             (L-45c) CFThree
H CH (CHThree) CH2OC (O) CHThree           CFThree              L-45f
H CH (CHThree) CH2OC (O) CHThree           CFThree             (L-46c) CFThree
H CH (CHThree) CH2OC (O) CHThree           CFThree              L-46d
H CH (CHThree) CH2OC (O) CFThree           CFThree              Ph-4-OCFThree
H CH (CHThree) CH2OC (O) NHCHThree         CFThree              CF2O (Ph-4-Cl)
H CH (CHThree) CH2OC (O) NHCHThree         CFThree              CH = CH (Ph-4-Cl)
H CH (CHThree) CH2OC (O) NHCHThree         CFThree              CH = CH (Ph-4-Br)
H CH (CHThree) CH2OC (O) NHCHThree         CFThree              CH = CH (Ph-4-CFThree)
H CH (CHThree) CH2OC (O) NHCHThree         CFThree              CH = CH (Ph-4-OCFThree)
H CH (CHThree) CH2OC (O) NHCHThree         CFThree              CH = CH (Ph-3,4-Cl2)
H CH (CHThree) CH2OC (O) NHCHThree         CFThree              Ph-4-F
H CH (CHThree) CH2OC (O) NHCHThree         CFThree              Ph-4-Cl
H CH (CHThree) CH2OC (O) NHCHThree         CFThree              Ph-4-Br
H CH (CHThree) CH2OC (O) NHCHThree         CFThree              Ph-4-CFThree
H CH (CHThree) CH2OC (O) NHCHThree         CFThree              Ph-4-OCFThree
H CH (CHThree) CH2OC (O) NHCHThree         CFThree              Ph-4-OCF2Br
H CH (CHThree) CH2OC (O) NHCHThree         CFThree              Ph-4-OCF2CHF2
H CH (CHThree) CH2OC (O) NHCHThree         CFThree              Ph-4-OCF2CHFCFThree
H CH (CHThree) CH2OC (O) NHCHThree         CFThree              Ph-4-OCF2CHFOCFThree
H CH (CHThree) CH2OC (O) NHCHThree         CFThree              Ph-4-OCF2CHFOCF2CF2CFThree
H CH (CHThree) CH2OC (O) NHCHThree         CFThree              Ph-4-O (L-45g)
H CH (CHThree) CH2OC (O) NHCHThree         CFThree              Ph-3,4-F2
H CH (CHThree) CH2OC (O) NHCHThree         CFThree              Ph-3-F-4-Cl
H CH (CHThree) CH2OC (O) NHCHThree         CFThree              Ph-3,4-Cl2
H CH (CHThree) CH2OC (O) NHCHThree         CFThree              Ph (-3-OCF2O-4-)
H CH (CHThree) CH2OC (O) NHCHThree         CFThree              Ph (-3-OCF2CF2O-4-)
H CH (CHThree) CH2OC (O) NHCHThree         CFThree             (L-45c) CFThree
H CH (CHThree) CH2OC (O) NHCHThree         CFThree              L-45f
H CH (CHThree) CH2OC (O) NHCHThree         CFThree             (L-46c) CFThree
H CH (CHThree) CH2OC (O) NHCHThree         CFThree              L-46d
H CH (CHThree) CH2OC (O) NHEt CHThree              Ph-4-Br
H CH (CHThree) CH2OC (O) NHEt CHThree              Ph-4-CFThree
H CH (CHThree) CH2OC (O) NHEt CHThree              Ph-4-OCFThree
H CH (CHThree) CH2OC (O) NHEt CHThree             (L-45c) Cl
H CH (CHThree) CH2OC (O) NHEt CHThree             (L-45c) Br
H CH (CHThree) CH2OC (O) NHEt CHThree             (L-45c) CFThree
H CH (CHThree) CH2OC (O) NHEt Et (L-45c) CFThree
H CH (CHThree) CH2OC (O) NHEt n-Pr Ph-4-Br
H CH (CHThree) CH2OC (O) NHEt i-Pr Ph-4-CFThree
H CH (CHThree) CH2OC (O) NHEt c-Pr Ph-4-OCFThree
H CH (CHThree) CH2OC (O) NHEt CHF2            (L-45c) CFThree
H CH (CHThree) CH2OC (O) NHEt CFThree              CF2O (Ph-4-Cl)
H CH (CHThree) CH2OC (O) NHEt CFThree              CH = CH (Ph-4-Cl)
H CH (CHThree) CH2OC (O) NHEt CFThree              CH = CH (Ph-4-Br)
H CH (CHThree) CH2OC (O) NHEt CFThree              CH = CH (Ph-4-CFThree)
H CH (CHThree) CH2OC (O) NHEt CFThree              CH = CH (Ph-4-OCFThree)
H CH (CHThree) CH2OC (O) NHEt CFThree              CH = CH (Ph-3,4-Cl2)
H CH (CHThree) CH2OC (O) NHEt CFThree              Ph-4-F
H CH (CHThree) CH2OC (O) NHEt CFThree              Ph-4-Cl
H CH (CHThree) CH2OC (O) NHEt CFThree              Ph-4-Br
H CH (CHThree) CH2OC (O) NHEt CFThree              Ph-4-I
H CH (CHThree) CH2OC (O) NHEt CFThree              Ph-4-CFThree
H CH (CHThree) CH2OC (O) NHEt CFThree              Ph-4-OCHF2
H CH (CHThree) CH2OC (O) NHEt CFThree              Ph-4-OCFThree
H CH (CHThree) CH2OC (O) NHEt CFThree              Ph-4-OCF2Br
H CH (CHThree) CH2OC (O) NHEt CFThree              Ph-4-OCF2CHF2
H CH (CHThree) CH2OC (O) NHEt CFThree              Ph-4-OCF2CHFCl
H CH (CHThree) CH2OC (O) NHEt CFThree              Ph-4-OCF2CHFCFThree
H CH (CHThree) CH2OC (O) NHEt CFThree              Ph-4-OCF2CHFOCFThree
H CH (CHThree) CH2OC (O) NHEt CFThree              Ph-4-OCF2CHFOCF2CF2CFThree
H CH (CHThree) CH2OC (O) NHEt CFThree              Ph-4-O (L-45g)
H CH (CHThree) CH2OC (O) NHEt CFThree              Ph-3,4-F2
H CH (CHThree) CH2OC (O) NHEt CFThree              Ph-3-F-4-Cl
H CH (CHThree) CH2OC (O) NHEt CFThree              Ph-3,4-Cl2
H CH (CHThree) CH2OC (O) NHEt CFThree              Ph (-3-OCF2O-4-)
H CH (CHThree) CH2OC (O) NHEt CFThree              Ph (-3-OCF2CF2O-4-)
H CH (CHThree) CH2OC (O) NHEt CFThree             (L-45c) Cl
H CH (CHThree) CH2OC (O) NHEt CFThree             (L-45c) Br
H CH (CHThree) CH2OC (O) NHEt CFThree             (L-45c) CFThree
H CH (CHThree) CH2OC (O) NHEt CFThree              L-45e
H CH (CHThree) CH2OC (O) NHEt CFThree              L-45f
H CH (CHThree) CH2OC (O) NHEt CFThree             (L-46c) Cl
H CH (CHThree) CH2OC (O) NHEt CFThree             (L-46c) Br
H CH (CHThree) CH2OC (O) NHEt CFThree             (L-46c) CFThree
H CH (CHThree) CH2OC (O) NHEt CFThree              L-46d
H CH (CHThree) CH2OC (O) NHEt CF2Cl Ph-4-Br
H CH (CHThree) CH2OC (O) NHEt CF2Br Ph-4-CFThree
H CH (CHThree) CH2OC (O) NHEt CF2CFThree           Ph-4-OCFThree
H CH (CHThree) CH2OC (O) NHEt CF2CF2CFThree       (L-45c) CFThree
H CH (CHThree) CH2OC (O) NHEt CF2OCHThree          Ph-4-Br
H CH (CHThree) CH2OC (O) NHEt CF2SCHThree          Ph-4-CFThree
H CH (CHThree) CH2OC (O) NHPr-n CFThree              CH = CH (Ph-4-Cl)
H CH (CHThree) CH2OC (O) NHPr-n CFThree              Ph-4-Cl
H CH (CHThree) CH2OC (O) NHPr-n CFThree              Ph-4-Br
H CH (CHThree) CH2OC (O) NHPr-n CFThree              Ph-4-CFThree
H CH (CHThree) CH2OC (O) NHPr-n CFThree              Ph-4-OCFThree
H CH (CHThree) CH2OC (O) NHPr-n CFThree              Ph-4-OCF2Br
H CH (CHThree) CH2OC (O) NHPr-n CFThree              Ph-4-OCF2CHFCFThree
H CH (CHThree) CH2OC (O) NHPr-n CFThree              Ph-4-OCF2CHFOCFThree
H CH (CHThree) CH2OC (O) NHPr-n CFThree              Ph-4-OCF2CHFOCF2CF2CFThree
H CH (CHThree) CH2OC (O) NHPr-n CFThree              Ph-4-O (L-45g)
H CH (CHThree) CH2OC (O) NHPr-n CFThree              Ph-3,4-Cl2
H CH (CHThree) CH2OC (O) NHPr-n CFThree              Ph (-3-OCF2O-4-)
H CH (CHThree) CH2OC (O) NHPr-n CFThree              Ph (-3-OCF2CF2O-4-)
H CH (CHThree) CH2OC (O) NHPr-n CFThree             (L-45c) CFThree
H CH (CHThree) CH2OC (O) NHPr-n CFThree              L-45f
H CH (CHThree) CH2OC (O) NHPr-n CFThree             (L-46c) CFThree
H CH (CHThree) CH2OC (O) NHPr-n CFThree              L-46d
H CH (CHThree) CH2OC (O) NHPr-i CFThree              CH = CH (Ph-4-Cl)
H CH (CHThree) CH2OC (O) NHPr-i CFThree              Ph-4-Cl
H CH (CHThree) CH2OC (O) NHPr-i CFThree              Ph-4-Br
H CH (CHThree) CH2OC (O) NHPr-i CFThree              Ph-4-CFThree
H CH (CHThree) CH2OC (O) NHPr-i CFThree              Ph-4-OCFThree
H CH (CHThree) CH2OC (O) NHPr-i CFThree              Ph-4-OCF2Br
H CH (CHThree) CH2OC (O) NHPr-i CFThree              Ph-4-OCF2CHFCFThree
H CH (CHThree) CH2OC (O) NHPr-i CFThree              Ph-4-OCF2CHFOCFThree
H CH (CHThree) CH2OC (O) NHPr-i CFThree              Ph-4-OCF2CHFOCF2CF2CFThree
H CH (CHThree) CH2OC (O) NHPr-i CFThree              Ph-4-O (L-45g)
H CH (CHThree) CH2OC (O) NHPr-i CFThree              Ph-3,4-Cl2
H CH (CHThree) CH2OC (O) NHPr-i CFThree              Ph (-3-OCF2O-4-)
H CH (CHThree) CH2OC (O) NHPr-i CFThree              Ph (-3-OCF2CF2O-4-)
H CH (CHThree) CH2OC (O) NHPr-i CFThree             (L-45c) CFThree
H CH (CHThree) CH2OC (O) NHPr-i CFThree              L-45f
H CH (CHThree) CH2OC (O) NHPr-i CFThree             (L-46c) CFThree
H CH (CHThree) CH2OC (O) NHPr-i CFThree              L-46d
H CH (CHThree) CH2OC (O) NHPr-c CFThree              CH = CH (Ph-4-Cl)
H CH (CHThree) CH2OC (O) NHPr-c CFThree              Ph-4-Cl
H CH (CHThree) CH2OC (O) NHPr-c CFThree              Ph-4-Br
H CH (CHThree) CH2OC (O) NHPr-c CFThree              Ph-4-CFThree
H CH (CHThree) CH2OC (O) NHPr-c CFThree              Ph-4-OCFThree
H CH (CHThree) CH2OC (O) NHPr-c CFThree              Ph-4-OCF2Br
H CH (CHThree) CH2OC (O) NHPr-c CFThree              Ph-4-OCF2CHFCFThree
H CH (CHThree) CH2OC (O) NHPr-c CFThree              Ph-4-OCF2CHFOCFThree
H CH (CHThree) CH2OC (O) NHPr-c CFThree              Ph-4-OCF2CHFOCF2CF2CFThree
H CH (CHThree) CH2OC (O) NHPr-c CFThree              Ph-4-O (L-45g)
H CH (CHThree) CH2OC (O) NHPr-c CFThree              Ph-3,4-Cl2
H CH (CHThree) CH2OC (O) NHPr-c CFThree              Ph (-3-OCF2O-4-)
H CH (CHThree) CH2OC (O) NHPr-c CFThree              Ph (-3-OCF2CF2O-4-)
H CH (CHThree) CH2OC (O) NHPr-c CFThree             (L-45c) CFThree
H CH (CHThree) CH2OC (O) NHPr-c CFThree              L-45f
H CH (CHThree) CH2OC (O) NHPr-c CFThree             (L-46c) CFThree
H CH (CHThree) CH2OC (O) NHPr-c CFThree              L-46d
H CH (CHThree) CH2OC (O) NHBu-t CFThree              Ph-4-OCFThree
H CH (CHThree) CH2OC (O) NHCH2CFThree      CFThree             (L-45c) CFThree
H CH (CHThree) CH2OC (O) NHCH2CH2OCHThree  CFThree              Ph-4-Br
H CH (CHThree) CH2OC (O) NHCH2CH2SCHThree  CFThree              Ph-4-CFThree 
H CH (CHThree) CH2OC (O) NHCH2CH2CH2SCHThree      CFThree       Ph-4-OCFThree
H CH (CHThree) CH2OC (O) NHCH2CH = CH2   CFThree             (L-45c) CFThree
H CH (CHThree) CH2OC (O) NHCH2Ph CFThree              CH = CH (Ph-4-Cl)
H CH (CHThree) CH2OC (O) NHCH2Ph CFThree              Ph-4-Cl
H CH (CHThree) CH2OC (O) NHCH2Ph CFThree              Ph-4-Br
H CH (CHThree) CH2OC (O) NHCH2Ph CFThree              Ph-4-CFThree
H CH (CHThree) CH2OC (O) NHCH2Ph CFThree              Ph-4-OCFThree
H CH (CHThree) CH2OC (O) NHCH2Ph CFThree              Ph-4-OCF2Br
H CH (CHThree) CH2OC (O) NHCH2Ph CFThree              Ph-4-OCF2CHFCFThree
H CH (CHThree) CH2OC (O) NHCH2Ph CFThree              Ph-4-OCF2CHFOCFThree
H CH (CHThree) CH2OC (O) NHCH2Ph CFThree              Ph-4-OCF2CHFOCF2CF2CFThree
H CH (CHThree) CH2OC (O) NHCH2Ph CFThree              Ph-4-O (L-45g)
H CH (CHThree) CH2OC (O) NHCH2Ph CFThree              Ph-3,4-Cl2
H CH (CHThree) CH2OC (O) NHCH2Ph CFThree              Ph (-3-OCF2O-4-)
H CH (CHThree) CH2OC (O) NHCH2Ph CFThree              Ph (-3-OCF2CF2O-4-)
H CH (CHThree) CH2OC (O) NHCH2Ph CFThree             (L-45c) CFThree
H CH (CHThree) CH2OC (O) NHCH2Ph CFThree              L-45f
H CH (CHThree) CH2OC (O) NHCH2Ph CFThree             (L-46c) CFThree
H CH (CHThree) CH2OC (O) NHCH2Ph CFThree              L-46d
H CH (CHThree) CH2OC (O) NHCH2(Ph-4-Cl) CFThree       Ph-4-Br
H CH (CHThree) CH2OC (O) NHCH2(Ph-4-OCHThree) CFThree       Ph-4-CFThree 
H CH (CHThree) CH2OC (O) NHCH2(L-46a) CFThree       Ph-4-OCFThree
H CH (CHThree) CH2OC (O) NHCH2(L-47a) CFThree      (L-45c) CFThree
H CH (CHThree) CH2OC (O) NHPh CFThree              CH = CH (Ph-4-Cl)
H CH (CHThree) CH2OC (O) NHPh CFThree              Ph-4-Cl
H CH (CHThree) CH2OC (O) NHPh CFThree              Ph-4-Br
H CH (CHThree) CH2OC (O) NHPh CFThree              Ph-4-CFThree
H CH (CHThree) CH2OC (O) NHPh CFThree              Ph-4-OCFThree
H CH (CHThree) CH2OC (O) NHPh CFThree              Ph-4-OCF2Br
H CH (CHThree) CH2OC (O) NHPh CFThree              Ph-4-OCF2CHFCFThree
H CH (CHThree) CH2OC (O) NHPh CFThree              Ph-4-OCF2CHFOCFThree
H CH (CHThree) CH2OC (O) NHPh CFThree              Ph-4-OCF2CHFOCF2CF2CFThree
H CH (CHThree) CH2OC (O) NHPh CFThree              Ph-4-O (L-45g)
H CH (CHThree) CH2OC (O) NHPh CFThree              Ph-3,4-Cl2
H CH (CHThree) CH2OC (O) NHPh CFThree              Ph (-3-OCF2O-4-)
H CH (CHThree) CH2OC (O) NHPh CFThree              Ph (-3-OCF2CF2O-4-)
H CH (CHThree) CH2OC (O) NHPh CFThree             (L-45c) CFThree
H CH (CHThree) CH2OC (O) NHPh CFThree              L-45f
H CH (CHThree) CH2OC (O) NHPh CFThree             (L-46c) CFThree
H CH (CHThree) CH2OC (O) NHPh CFThree              L-46d
H CH (CHThree) CH2OC (O) N (CHThree)2       CFThree              Ph-4-Br
H CH (CHThree) CH2OC (O) N (Et)2        CFThree              CH = CH (Ph-4-Cl)
H CH (CHThree) CH2OC (O) N (Et)2        CFThree              Ph-4-Cl
H CH (CHThree) CH2OC (O) N (Et)2        CFThree              Ph-4-Br
H CH (CHThree) CH2OC (O) N (Et)2        CFThree              Ph-4-CFThree
H CH (CHThree) CH2OC (O) N (Et)2        CFThree              Ph-4-OCFThree
H CH (CHThree) CH2OC (O) N (Et)2        CFThree              Ph-4-OCF2Br
H CH (CHThree) CH2OC (O) N (Et)2        CFThree              Ph-4-OCF2CHFCFThree
H CH (CHThree) CH2OC (O) N (Et)2        CFThree              Ph-4-OCF2CHFOCFThree
H CH (CHThree) CH2OC (O) N (Et)2        CFThree              Ph-4-OCF2CHFOCF2CF2CFThree
H CH (CHThree) CH2OC (O) N (Et)2        CFThree              Ph-4-O (L-45g)
H CH (CHThree) CH2OC (O) N (Et)2        CFThree              Ph-3,4-Cl2
H CH (CHThree) CH2OC (O) N (Et)2        CFThree              Ph (-3-OCF2O-4-)
H CH (CHThree) CH2OC (O) N (Et)2        CFThree              Ph (-3-OCF2CF2O-4-)
H CH (CHThree) CH2OC (O) N (Et)2        CFThree             (L-45c) CFThree
H CH (CHThree) CH2OC (O) N (Et)2        CFThree              L-45f
H CH (CHThree) CH2OC (O) N (Et)2        CFThree             (L-46c) CFThree
H CH (CHThree) CH2OC (O) N (Et)2        CFThree              L-46d
H CH (CHThree) CH2OC (O) N (Pr-i)2      CFThree              Ph-4-CFThree
H CH (CHThree) CH2OC (O) N (CHThree) Ph CFThree              Ph-4-OCFThree
H CH (CHThree) CH2OC (O) (T-16) CFThree             (L-45c) CFThree
H CH (CHThree) CH2OC (O) (T-19) CFThree              Ph-4-Br
H CH (CHThree) CH2OC (O) (T-20) CFThree              Ph-4-CFThree
H CH (CHThree) CH2OC (O) (T-21) CFThree              Ph-4-OCFThree
H CH (CHThree) CH2OP (O) (OEt)2        CFThree             (L-45c) CFThree
H CH (CHThree) CH2OP (S) (OCHThree)2       CFThree              CH = CH (Ph-4-Cl)
H CH (CHThree) CH2OP (S) (OCHThree)2       CFThree              Ph-4-Cl
H CH (CHThree) CH2OP (S) (OCHThree)2       CFThree              Ph-4-Br
H CH (CHThree) CH2OP (S) (OCHThree)2       CFThree              Ph-4-CFThree
H CH (CHThree) CH2OP (S) (OCHThree)2       CFThree              Ph-4-OCFThree
H CH (CHThree) CH2OP (S) (OCHThree)2       CFThree              Ph-4-OCF2Br
H CH (CHThree) CH2OP (S) (OCHThree)2       CFThree              Ph-4-OCF2CHFCFThree
H CH (CHThree) CH2OP (S) (OCHThree)2       CFThree              Ph-4-OCF2CHFOCFThree
H CH (CHThree) CH2OP (S) (OCHThree)2       CFThree              Ph-4-OCF2CHFOCF2CF2CFThree
H CH (CHThree) CH2OP (S) (OCHThree)2       CFThree              Ph-4-O (L-45g)
H CH (CHThree) CH2OP (S) (OCHThree)2       CFThree              Ph-3,4-Cl2
H CH (CHThree) CH2OP (S) (OCHThree)2       CFThree              Ph (-3-OCF2O-4-)
H CH (CHThree) CH2OP (S) (OCHThree)2       CFThree              Ph (-3-OCF2CF2O-4-)
H CH (CHThree) CH2OP (S) (OCHThree)2       CFThree             (L-45c) CFThree
H CH (CHThree) CH2OP (S) (OCHThree)2       CFThree              L-45f
H CH (CHThree) CH2OP (S) (OCHThree)2       CFThree             (L-46c) CFThree
H CH (CHThree) CH2OP (S) (OCHThree)2       CFThree              L-46d
H CH (CHThree) CH2OP (S) (OEt)2        CFThree              CH = CH (Ph-4-Cl)
H CH (CHThree) CH2OP (S) (OEt)2        CFThree              Ph-4-Cl
H CH (CHThree) CH2OP (S) (OEt)2        CFThree              Ph-4-Br
H CH (CHThree) CH2OP (S) (OEt)2        CFThree              Ph-4-CFThree
H CH (CHThree) CH2OP (S) (OEt)2        CFThree              Ph-4-OCFThree
H CH (CHThree) CH2OP (S) (OEt)2        CFThree              Ph-4-OCF2Br
H CH (CHThree) CH2OP (S) (OEt)2        CFThree              Ph-4-OCF2CHFCFThree
H CH (CHThree) CH2OP (S) (OEt)2        CFThree              Ph-4-OCF2CHFOCFThree
H CH (CHThree) CH2OP (S) (OEt)2        CFThree              Ph-4-OCF2CHFOCF2CF2CFThree
H CH (CHThree) CH2OP (S) (OEt)2        CFThree              Ph-4-O (L-45g)
H CH (CHThree) CH2OP (S) (OEt)2        CFThree              Ph-3,4-Cl2
H CH (CHThree) CH2OP (S) (OEt)2        CFThree              Ph (-3-OCF2O-4-)
H CH (CHThree) CH2OP (S) (OEt)2        CFThree              Ph (-3-OCF2CF2O-4-)
H CH (CHThree) CH2OP (S) (OEt)2        CFThree             (L-45c) CFThree
H CH (CHThree) CH2OP (S) (OEt)2        CFThree              L-45f
H CH (CHThree) CH2OP (S) (OEt)2        CFThree             (L-46c) CFThree
H CH (CHThree) CH2OP (S) (OEt)2        CFThree              L-46d
H CH (CHThree) CH2OPh CFThree              Ph-4-Br
H CH (CHThree) CH2O (Ph-4-Cl) CFThree              CH = CH (Ph-4-Cl)
H CH (CHThree) CH2O (Ph-4-Cl) CFThree              Ph-4-Cl
H CH (CHThree) CH2O (Ph-4-Cl) CFThree              Ph-4-Br
H CH (CHThree) CH2O (Ph-4-Cl) CFThree              Ph-4-CFThree
H CH (CHThree) CH2O (Ph-4-Cl) CFThree              Ph-4-OCFThree
H CH (CHThree) CH2O (Ph-4-Cl) CFThree              Ph-4-OCF2Br
H CH (CHThree) CH2O (Ph-4-Cl) CFThree              Ph-4-OCF2CHFCFThree
H CH (CHThree) CH2O (Ph-4-Cl) CFThree              Ph-4-OCF2CHFOCFThree
H CH (CHThree) CH2O (Ph-4-Cl) CFThree              Ph-4-OCF2CHFOCF2CF2CFThree
H CH (CHThree) CH2O (Ph-4-Cl) CFThree              Ph-4-O (L-45g)
H CH (CHThree) CH2O (Ph-4-Cl) CFThree              Ph-3,4-Cl2
H CH (CHThree) CH2O (Ph-4-Cl) CFThree              Ph (-3-OCF2O-4-)
H CH (CHThree) CH2O (Ph-4-Cl) CFThree              Ph (-3-OCF2CF2O-4-)
H CH (CHThree) CH2O (Ph-4-Cl) CFThree             (L-45c) CFThree
H CH (CHThree) CH2O (Ph-4-Cl) CFThree              L-45f
H CH (CHThree) CH2O (Ph-4-Cl) CFThree             (L-46c) CFThree
H CH (CHThree) CH2O (Ph-4-Cl) CFThree              L-46d
H CH (CHThree) CH2O (Ph-3-CFThree) CFThree              Ph-4-CFThree
H CH (Et) CH2OH CFThree              Ph-4-OCFThree
H CH (Et) CH2OCHThree                CFThree             (L-45c) CFThree
H CH (Ph) CH2OH CFThree              Ph-4-Br
H CH (Ph) CH2OH (R) CFThree              Ph-4-Br
H CH (Ph-2-Cl) CH2OH CFThree              Ph-4-CFThree
H CH (Ph-4-Cl) CH2OH CFThree              Ph-4-OCFThree
H CH (Ph-4-Ph) CH2OH CFThree             (L-45c) CFThree
H C (CHThree)2CH2OH CFThree              Ph-4-Br
H CH (CHThree) CH2OCHThree               CHThree              Ph-4-Br
H C (CHThree)2CH2OCHThree               CHThree              Ph-4-CFThree
H C (CHThree)2CH2OCHThree               CHThree              Ph-4-OCFThree
H C (CHThree)2CH2OCHThree               CHThree             (L-45c) Cl
H C (CHThree)2CH2OCHThree               CHThree             (L-45c) Br
H C (CHThree)2CH2OCHThree               CHThree             (L-45c) CFThree
H C (CHThree)2CH2OCHThree               Et Ph-4-CFThree
H C (CHThree)2CH2OCHThree               n-Pr Ph-4-OCFThree
H C (CHThree)2CH2OCHThree               i-Pr (L-45c) CFThree
H C (CHThree)2CH2OCHThree               c-Pr Ph-4-Br
H C (CHThree)2CH2OCHThree               CHF2             Ph-4-CFThree
H C (CHThree)2CH2OCHThree               CFThree              CF2O (Ph-4-Cl)
H C (CHThree)2CH2OCHThree               CFThree              CH = CH (Ph-4-Cl)
H C (CHThree)2CH2OCHThree               CFThree              CH = CH (Ph-4-OCFThree)
H C (CHThree)2CH2OCHThree               CFThree              CH = CH (Ph-3,4-Cl2)
H C (CHThree)2CH2OCHThree               CFThree              Ph-4-F
H C (CHThree)2CH2OCHThree               CFThree              Ph-4-Cl
H C (CHThree)2CH2OCHThree               CFThree              Ph-4-Br
H C (CHThree)2CH2OCHThree               CFThree              Ph-4-I
H C (CHThree)2CH2OCHThree               CFThree              Ph-4-CFThree
H C (CHThree)2CH2OCHThree               CFThree              Ph-4-OCHF2
H C (CHThree)2CH2OCHThree               CFThree              Ph-4-OCFThree
H C (CHThree)2CH2OCHThree               CFThree              Ph-4-OCF2Br
H C (CHThree)2CH2OCHThree               CFThree              Ph-4-OCF2CHF2
H C (CHThree)2CH2OCHThree               CFThree              Ph-4-OCF2CHFCl
H C (CHThree)2CH2OCHThree               CFThree              Ph-4-OCF2CHFCFThree
H C (CHThree)2CH2OCHThree               CFThree              Ph-4-OCF2CHFOCFThree
H C (CHThree)2CH2OCHThree               CFThree              Ph-4-OCF2CHFOCF2CF2CFThree
H C (CHThree)2CH2OCHThree               CFThree              Ph-4-O (L-45g)
H C (CHThree)2CH2OCHThree               CFThree              Ph-3,4-Cl2
H C (CHThree)2CH2OCHThree               CFThree              Ph (-3-OCF2O-4-)
H C (CHThree)2CH2OCHThree               CFThree              Ph (-3-OCF2CF2O-4-)
H C (CHThree)2CH2OCHThree               CFThree             (L-45c) Cl
H C (CHThree)2CH2OCHThree               CFThree             (L-45c) Br
H C (CHThree)2CH2OCHThree               CFThree             (L-45c) CFThree
H C (CHThree)2CH2OCHThree               CFThree              L-45e
H C (CHThree)2CH2OCHThree               CFThree              L-45f
H C (CHThree)2CH2OCHThree               CFThree             (L-46c) Cl
H C (CHThree)2CH2OCHThree               CFThree             (L-46c) Br
H C (CHThree)2CH2OCHThree               CFThree             (L-46c) CFThree
H C (CHThree)2CH2OCHThree               CFThree              L-46d
H C (CHThree)2CH2OCHThree               CF2Cl Ph-4-OCFThree
H C (CHThree)2CH2OCHThree               CF2Br (L-45c) CFThree
H C (CHThree)2CH2OCHThree               CF2CFThree           Ph-4-Br
H C (CHThree)2CH2OCHThree               CF2CF2CFThree        Ph-4-CFThree
H C (CHThree)2CH2OCHThree               CF2OCHThree          Ph-4-OCFThree
H C (CHThree)2CH2OCHThree               CF2SCHThree         (L-45c) CFThree
H C (CHThree)2CH2OC (O) CHThree           CFThree              Ph-4-Br
H C (CHThree)2CH2OC (O) CFThree           CFThree              Ph-4-CFThree
H C (CHThree)2CH2OC (O) NHCHThree         CHThree              Ph-4-Br
H C (CHThree)2CH2OC (O) NHCHThree         CHThree              Ph-4-CFThree
H C (CHThree)2CH2OC (O) NHCHThree         CHThree              Ph-4-OCFThree
H C (CHThree)2CH2OC (O) NHCHThree         CHThree             (L-45c) Cl
H C (CHThree)2CH2OC (O) NHCHThree         CHThree             (L-45c) Br
H C (CHThree)2CH2OC (O) NHCHThree         CHThree             (L-45c) CFThree
H C (CHThree)2CH2OC (O) NHCHThree         Et Ph-4-OCFThree
H C (CHThree)2CH2OC (O) NHCHThree         n-Pr (L-45c) CFThree
H C (CHThree)2CH2OC (O) NHCHThree         i-Pr Ph-4-Br
H C (CHThree)2CH2OC (O) NHCHThree         c-Pr Ph-4-CFThree
H C (CHThree)2CH2OC (O) NHCHThree         CHF2             Ph-4-OCFThree
H C (CHThree)2CH2OC (O) NHCHThree         CFThree              CF2O (Ph-4-Cl)
H C (CHThree)2CH2OC (O) NHCHThree         CFThree              CH = CH (Ph-4-Cl)
H C (CHThree)2CH2OC (O) NHCHThree         CFThree              CH = CH (Ph-4-Br)
H C (CHThree)2CH2OC (O) NHCHThree         CFThree              CH = CH (Ph-4-CFThree)
H C (CHThree)2CH2OC (O) NHCHThree         CFThree              CH = CH (Ph-4-OCFThree)
H C (CHThree)2CH2OC (O) NHCHThree         CFThree              CH = CH (Ph-3,4-Cl2)
H C (CHThree)2CH2OC (O) NHCHThree         CFThree              Ph-4-F
H C (CHThree)2CH2OC (O) NHCHThree         CFThree              Ph-4-Cl
H C (CHThree)2CH2OC (O) NHCHThree         CFThree              Ph-4-Br
H C (CHThree)2CH2OC (O) NHCHThree         CFThree              Ph-4-I
H C (CHThree)2CH2OC (O) NHCHThree         CFThree              Ph-4-CFThree
H C (CHThree)2CH2OC (O) NHCHThree         CFThree              Ph-4-OCHF2
H C (CHThree)2CH2OC (O) NHCHThree         CFThree              Ph-4-OCFThree
H C (CHThree)2CH2OC (O) NHCHThree         CFThree              Ph-4-OCF2Br
H C (CHThree)2CH2OC (O) NHCHThree         CFThree              Ph-4-OCF2CHF2
H C (CHThree)2CH2OC (O) NHCHThree         CFThree              Ph-4-OCF2CHFCl
H C (CHThree)2CH2OC (O) NHCHThree         CFThree              Ph-4-OCF2CHFCFThree
H C (CHThree)2CH2OC (O) NHCHThree         CFThree              Ph-4-OCF2CHFOCFThree
H C (CHThree)2CH2OC (O) NHCHThree         CFThree              Ph-4-OCF2CHFOCF2CF2CFThree
H C (CHThree)2CH2OC (O) NHCHThree         CFThree              Ph-4-O (L-45g)
H C (CHThree)2CH2OC (O) NHCHThree         CFThree              Ph-3,4-F2
H C (CHThree)2CH2OC (O) NHCHThree         CFThree              Ph-3-F-4-Cl
H C (CHThree)2CH2OC (O) NHCHThree         CFThree              Ph-3,4-Cl2
H C (CHThree)2CH2OC (O) NHCHThree         CFThree              Ph (-3-OCF2O-4-)
H C (CHThree)2CH2OC (O) NHCHThree         CFThree              Ph (-3-OCF2CF2O-4-)
H C (CHThree)2CH2OC (O) NHCHThree         CFThree             (L-45c) Cl
H C (CHThree)2CH2OC (O) NHCHThree         CFThree             (L-45c) Br
H C (CHThree)2CH2OC (O) NHCHThree         CFThree             (L-45c) CFThree
H C (CHThree)2CH2OC (O) NHCHThree         CFThree              L-45e
H C (CHThree)2CH2OC (O) NHCHThree         CFThree              L-45f
H C (CHThree)2CH2OC (O) NHCHThree         CFThree             (L-46c) Cl
H C (CHThree)2CH2OC (O) NHCHThree         CFThree             (L-46c) Br
H C (CHThree)2CH2OC (O) NHCHThree         CFThree             (L-46c) CFThree
H C (CHThree)2CH2OC (O) NHCHThree         CFThree              L-46d
H C (CHThree)2CH2OC (O) NHCHThree         CF2Cl (L-45c) CFThree
H C (CHThree)2CH2OC (O) NHCHThree         CF2Br Ph-4-Br
H C (CHThree)2CH2OC (O) NHCHThree         CF2CFThree           Ph-4-CFThree
H C (CHThree)2CH2OC (O) NHCHThree         CF2CF2CFThree        Ph-4-OCFThree
H C (CHThree)2CH2OC (O) NHCHThree         CF2OCHThree         (L-45c) CFThree
H C (CHThree)2CH2OC (O) NHCHThree         CF2SCHThree          Ph-4-Br
H C (CHThree)2CH2OC (O) NHEt CFThree              CF2O (Ph-4-Cl)
H C (CHThree)2CH2OC (O) NHEt CFThree              CH = CH (Ph-4-Cl)
H C (CHThree)2CH2OC (O) NHEt CFThree              CH = CH (Ph-4-Br)
H C (CHThree)2CH2OC (O) NHEt CFThree              CH = CH (Ph-4-CFThree)
H C (CHThree)2CH2OC (O) NHEt CFThree              CH = CH (Ph-4-OCFThree)
H C (CHThree)2CH2OC (O) NHEt CFThree              CH = CH (Ph-3,4-Cl2)
H C (CHThree)2CH2OC (O) NHEt CFThree              Ph-4-F
H C (CHThree)2CH2OC (O) NHEt CFThree              Ph-4-Cl
H C (CHThree)2CH2OC (O) NHEt CFThree              Ph-4-Br
H C (CHThree)2CH2OC (O) NHEt CFThree              Ph-4-CFThree
H C (CHThree)2CH2OC (O) NHEt CFThree              Ph-4-OCFThree
H C (CHThree)2CH2OC (O) NHEt CFThree              Ph-4-OCF2Br
H C (CHThree)2CH2OC (O) NHEt CFThree              Ph-4-OCF2CHF2
H C (CHThree)2CH2OC (O) NHEt CFThree              Ph-4-OCF2CHFCFThree
H C (CHThree)2CH2OC (O) NHEt CFThree              Ph-4-OCF2CHFOCFThree
H C (CHThree)2CH2OC (O) NHEt CFThree              Ph-4-OCF2CHFOCF2CF2CFThree
H C (CHThree)2CH2OC (O) NHEt CFThree              Ph-4-O (L-45g)
H C (CHThree)2CH2OC (O) NHEt CFThree              Ph-3,4-F2
H C (CHThree)2CH2OC (O) NHEt CFThree              Ph-3-F-4-Cl
H C (CHThree)2CH2OC (O) NHEt CFThree              Ph-3,4-Cl2
H C (CHThree)2CH2OC (O) NHEt CFThree              Ph (-3-OCF2O-4-)
H C (CHThree)2CH2OC (O) NHEt CFThree              Ph (-3-OCF2CF2O-4-)
H C (CHThree)2CH2OC (O) NHEt CFThree             (L-45c) CFThree
H C (CHThree)2CH2OC (O) NHEt CFThree              L-45f
H C (CHThree)2CH2OC (O) NHEt CFThree             (L-46c) CFThree
H C (CHThree)2CH2OC (O) NHEt CFThree              L-46d
H C (CHThree)2CH2OC (O) NHPr-n CFThree              CH = CH (Ph-4-Cl)
H C (CHThree)2CH2OC (O) NHPr-n CFThree              Ph-4-Cl
H C (CHThree)2CH2OC (O) NHPr-n CFThree              Ph-4-Br
H C (CHThree)2CH2OC (O) NHPr-n CFThree              Ph-4-CFThree
H C (CHThree)2CH2OC (O) NHPr-n CFThree              Ph-4-OCFThree
H C (CHThree)2CH2OC (O) NHPr-n CFThree              Ph-4-OCF2Br
H C (CHThree)2CH2OC (O) NHPr-n CFThree              Ph-4-OCF2CHFCFThree
H C (CHThree)2CH2OC (O) NHPr-n CFThree              Ph-4-OCF2CHFOCFThree
H C (CHThree)2CH2OC (O) NHPr-n CFThree              Ph-4-OCF2CHFOCF2CF2CFThree
H C (CHThree)2CH2OC (O) NHPr-n CFThree              Ph-4-O (L-45g)
H C (CHThree)2CH2OC (O) NHPr-n CFThree              Ph-3,4-Cl2
H C (CHThree)2CH2OC (O) NHPr-n CFThree              Ph (-3-OCF2O-4-)
H C (CHThree)2CH2OC (O) NHPr-n CFThree              Ph (-3-OCF2CF2O-4-)
H C (CHThree)2CH2OC (O) NHPr-n CFThree             (L-45c) CFThree
H C (CHThree)2CH2OC (O) NHPr-n CFThree              L-45f
H C (CHThree)2CH2OC (O) NHPr-n CFThree             (L-46c) CFThree
H C (CHThree)2CH2OC (O) NHPr-n CFThree              L-46d
H C (CHThree)2CH2OC (O) NHPr-i CFThree              Ph-4-CFThree
H C (CHThree)2CH2OC (O) NHPr-c CFThree              Ph-4-OCFThree
H C (CHThree)2CH2OC (O) NHCH2CFThree      CFThree             (L-45c) CFThree
H C (CHThree)2CH2OC (O) NHCH2CH2OCHThree  CFThree              Ph-4-Br
H C (CHThree)2CH2OC (O) NHCH2CH2SCHThree  CFThree              Ph-4-CFThree
H C (CHThree)2CH2OC (O) NHCH2CH2CH2SCHThree      CFThree       Ph-4-OCFThree
H C (CHThree)2CH2OC (O) NHCH2CH = CH2   CFThree              Ph-4-CFThree
H C (CHThree)2CH2OC (O) NHCH2Ph CFThree              CH = CH (Ph-4-Cl)
H C (CHThree)2CH2OC (O) NHCH2Ph CFThree              Ph-4-Cl
H C (CHThree)2CH2OC (O) NHCH2Ph CFThree              Ph-4-Br
H C (CHThree)2CH2OC (O) NHCH2Ph CFThree              Ph-4-CFThree
H C (CHThree)2CH2OC (O) NHCH2Ph CFThree              Ph-4-OCFThree
H C (CHThree)2CH2OC (O) NHCH2Ph CFThree              Ph-4-OCF2Br
H C (CHThree)2CH2OC (O) NHCH2Ph CFThree              Ph-4-OCF2CHFCFThree
H C (CHThree)2CH2OC (O) NHCH2Ph CFThree              Ph-4-OCF2CHFOCFThree
H C (CHThree)2CH2OC (O) NHCH2Ph CFThree              Ph-4-OCF2CHFOCF2CF2CFThree
H C (CHThree)2CH2OC (O) NHCH2Ph CFThree              Ph-4-O (L-45g)
H C (CHThree)2CH2OC (O) NHCH2Ph CFThree              Ph-3,4-Cl2
H C (CHThree)2CH2OC (O) NHCH2Ph CFThree              Ph (-3-OCF2O-4-)
H C (CHThree)2CH2OC (O) NHCH2Ph CFThree              Ph (-3-OCF2CF2O-4-)
H C (CHThree)2CH2OC (O) NHCH2Ph CFThree             (L-45c) CFThree
H C (CHThree)2CH2OC (O) NHCH2Ph CFThree              L-45f
H C (CHThree)2CH2OC (O) NHCH2Ph CFThree             (L-46c) CFThree
H C (CHThree)2CH2OC (O) NHCH2Ph CFThree              L-46d
H C (CHThree)2CH2OC (O) N (CHThree)2       CFThree              CH = CH (Ph-4-Cl)
H C (CHThree)2CH2OC (O) N (CHThree)2       CFThree              Ph-4-Cl
H C (CHThree)2CH2OC (O) N (CHThree)2       CFThree              Ph-4-Br
H C (CHThree)2CH2OC (O) N (CHThree)2       CFThree              Ph-4-CFThree
H C (CHThree)2CH2OC (O) N (CHThree)2       CFThree              Ph-4-OCFThree
H C (CHThree)2CH2OC (O) N (CHThree)2       CFThree              Ph-4-OCF2Br
H C (CHThree)2CH2OC (O) N (CHThree)2       CFThree              Ph-4-OCF2CHFCFThree
H C (CHThree)2CH2OC (O) N (CHThree)2       CFThree              Ph-4-OCF2CHFOCFThree
H C (CHThree)2CH2OC (O) N (CHThree)2       CFThree              Ph-4-OCF2CHFOCF2CF2CFThree
H C (CHThree)2CH2OC (O) N (CHThree)2       CFThree              Ph-4-O (L-45g)
H C (CHThree)2CH2OC (O) N (CHThree)2       CFThree              Ph-3,4-Cl2
H C (CHThree)2CH2OC (O) N (CHThree)2       CFThree              Ph (-3-OCF2O-4-)
H C (CHThree)2CH2OC (O) N (CHThree)2       CFThree              Ph (-3-OCF2CF2O-4-)
H C (CHThree)2CH2OC (O) N (CHThree)2       CFThree             (L-45c) CFThree
H C (CHThree)2CH2OC (O) N (CHThree)2       CFThree              L-45f
H C (CHThree)2CH2OC (O) N (CHThree)2       CFThree             (L-46c) CFThree
H C (CHThree)2CH2OC (O) N (CHThree)2       CFThree              L-46d
H C (CHThree)2CH2OP (S) (OCHThree)2       CFThree              Ph-4-OCFThree
H CH2CH2CH2OH CFThree             (L-45c) CFThree
H CH2CH2CH2OCHThree                CFThree              Ph-4-Br
H CH (CHThree) CH2CH2OCHThree            CFThree              Ph-4-CFThree
H CH (CHThree) CH2CH2OEt CFThree              CH = CH (Ph-4-Cl)
H CH (CHThree) CH2CH2OEt CFThree              Ph-4-Cl
H CH (CHThree) CH2CH2OEt CFThree              Ph-4-Br
H CH (CHThree) CH2CH2OEt CFThree              Ph-4-CFThree
H CH (CHThree) CH2CH2OEt CFThree              Ph-4-OCFThree
H CH (CHThree) CH2CH2OEt CFThree              Ph-4-OCF2Br
H CH (CHThree) CH2CH2OEt CFThree              Ph-4-OCF2CHFCFThree
H CH (CHThree) CH2CH2OEt CFThree              Ph-4-OCF2CHFOCFThree
H CH (CHThree) CH2CH2OEt CFThree              Ph-4-OCF2CHFOCF2CF2CFThree
H CH (CHThree) CH2CH2OEt CFThree              Ph-4-O (L-45g)
H CH (CHThree) CH2CH2OEt CFThree              Ph-3,4-Cl2
H CH (CHThree) CH2CH2OEt CFThree              Ph (-3-OCF2O-4-)
H CH (CHThree) CH2CH2OEt CFThree              Ph (-3-OCF2CF2O-4-)
H CH (CHThree) CH2CH2OEt CFThree             (L-45c) CFThree
H CH (CHThree) CH2CH2OEt CFThree              L-45f
H CH (CHThree) CH2CH2OEt CFThree             (L-46c) CFThree
H CH (CHThree) CH2CH2OEt CFThree              L-46d
H CH (CHThree) CH2CH2OPr-n CFThree              Ph-4-OCFThree
H CH (CHThree) CH2CH2OBu-i CFThree             (L-45c) CFThree
H CH (CHThree) CH2CH2OCH2CFThree         CFThree              Ph-4-Br
H CH (CHThree) CH2CH2OCH2CH2OCHThree     CFThree              Ph-4-CFThree
H CH (CHThree) CH2CH2OC (O) NHEt CFThree              Ph-4-OCFThree
H CH2CH2CH2CH2OC (O) NHEt CFThree             (L-45c) CFThree
H CH2CH2CH2CH2OC (O) NHPr-i CFThree              Ph-4-Br
H CH2CH2CH2CH2CH2OC (O) NHEt CFThree              Ph-4-CFThree
H T-10 CFThree              Ph-4-OCFThree
H M-4a CFThree             (L-45c) CFThree
H M-5a CFThree              Ph-4-Br
H CH2(M-7a) CFThree              Ph-4-CFThree
H CH2(M-16a) CFThree              Ph-4-OCFThree
 -CH2CH2OCH2CH2-CFThree             (L-45c) CFThree
H CH2SCHThree                      CFThree              Ph-4-Br
H CH2CH2SCHThree                   CFThree              Ph-4-CFThree
H CH2CH2SEt CFThree              Ph-4-OCFThree
H CH2CH2SPr-i CFThree             (L-45c) CFThree
H CH2CH (CHThree) SCHThree               CFThree              Ph-4-Br
H CH2CH (CHThree) SO2CHThree             CFThree              Ph-4-CFThree
H CH2CH (CHThree) SEt CFThree              Ph-4-OCFThree
H CH2CH (CHThree) SO2Et CFThree             (L-45c) CFThree
H CH (CHThree) CH2SH CFThree              Ph-4-Br
H CH (CHThree) CH2SCHThree               CHThree              CF2O (Ph-4-Cl)
H CH (CHThree) CH2SCHThree               CHThree              CH = CH (Ph-4-Cl)
H CH (CHThree) CH2SCHThree               CHThree              CH = CH (Ph-4-OCFThree)
H CH (CHThree) CH2SCHThree               CHThree              CH = CH (Ph-3,4-Cl2)
H CH (CHThree) CH2SCHThree               CHThree              Ph-4-F
H CH (CHThree) CH2SCHThree               CHThree              Ph-4-Cl
H CH (CHThree) CH2SCHThree               CHThree              Ph-4-Br
H CH (CHThree) CH2SCHThree               CHThree              Ph-4-I
H CH (CHThree) CH2SCHThree               CHThree              Ph-4-CFThree
H CH (CHThree) CH2SCHThree               CHThree              Ph-4-OCHF2
H CH (CHThree) CH2SCHThree               CHThree              Ph-4-OCFThree
H CH (CHThree) CH2SCHThree               CHThree              Ph-4-OCF2Br
H CH (CHThree) CH2SCHThree               CHThree              Ph-4-OCF2CHF2
H CH (CHThree) CH2SCHThree               CHThree              Ph-4-OCF2CHFCl
H CH (CHThree) CH2SCHThree               CHThree              Ph-4-OCF2CHFCFThree
H CH (CHThree) CH2SCHThree               CHThree              Ph-4-OCF2CHFOCFThree
H CH (CHThree) CH2SCHThree               CHThree              Ph-4-OCF2CHFOCF2CF2CFThree
H CH (CHThree) CH2SCHThree               CHThree              Ph-4-O (L-45g)
H CH (CHThree) CH2SCHThree               CHThree              Ph-3,4-Cl2
H CH (CHThree) CH2SCHThree               CHThree              Ph (-3-OCF2O-4-)
H CH (CHThree) CH2SCHThree               CHThree              Ph (-3-OCF2CF2O-4-)
H CH (CHThree) CH2SCHThree               CHThree             (L-45c) Cl
H CH (CHThree) CH2SCHThree               CHThree             (L-45c) Br
H CH (CHThree) CH2SCHThree               CHThree             (L-45c) CFThree
H CH (CHThree) CH2SCHThree               CHThree              L-45e
H CH (CHThree) CH2SCHThree               CHThree              L-45f
H CH (CHThree) CH2SCHThree               CHThree             (L-46c) Cl
H CH (CHThree) CH2SCHThree               CHThree             (L-46c) Br
H CH (CHThree) CH2SCHThree               CHThree             (L-46c) CFThree
H CH (CHThree) CH2SCHThree               CHThree              L-46d
H CH (CHThree) CH2SCHThree               Et Ph-4-Cl
H CH (CHThree) CH2SCHThree               Et Ph-4-Br
H CH (CHThree) CH2SCHThree               Et Ph-4-CFThree
H CH (CHThree) CH2SCHThree               Et Ph-4-OCFThree
H CH (CHThree) CH2SCHThree               Et Ph-4-OCF2Br
H CH (CHThree) CH2SCHThree               Et Ph-4-OCF2CHFCFThree
H CH (CHThree) CH2SCHThree               Et Ph-4-OCF2CHFOCFThree
H CH (CHThree) CH2SCHThree               Et Ph-4-OCF2CHFOCF2CF2CFThree
H CH (CHThree) CH2SCHThree               Et Ph-4-O (L-45g)
H CH (CHThree) CH2SCHThree               Et Ph-3,4-Cl2
H CH (CHThree) CH2SCHThree               Et Ph (-3-OCF2O-4-)
H CH (CHThree) CH2SCHThree               Et Ph (-3-OCF2CF2O-4-)
H CH (CHThree) CH2SCHThree               Et (L-45c) CFThree
H CH (CHThree) CH2SCHThree               n-Pr Ph-4-Br
H CH (CHThree) CH2SCHThree               n-Pr Ph-4-CFThree
H CH (CHThree) CH2SCHThree               n-Pr Ph-4-OCFThree
H CH (CHThree) CH2SCHThree               n-Pr (L-45c) CFThree
H CH (CHThree) CH2SCHThree               i-Pr Ph-4-Br
H CH (CHThree) CH2SCHThree               i-Pr Ph-4-CFThree
H CH (CHThree) CH2SCHThree               i-Pr Ph-4-OCFThree
H CH (CHThree) CH2SCHThree               i-Pr (L-45c) CFThree
H CH (CHThree) CH2SCHThree               c-Pr Ph-4-Br
H CH (CHThree) CH2SCHThree               c-Pr Ph-4-CFThree
H CH (CHThree) CH2SCHThree               c-Pr Ph-4-OCFThree
H CH (CHThree) CH2SCHThree               c-Pr (L-45c) CFThree
H CH (CHThree) CH2SCHThree               n-Bu Ph-4-CFThree
H CH (CHThree) CH2SCHThree               CH2F Ph-4-OCFThree
H CH (CHThree) CH2SCHThree               CH2Cl (L-45c) CFThree
H CH (CHThree) CH2SCHThree               CH2Br Ph-4-Br
H CH (CHThree) CH2SCHThree               CHF2             Ph-4-Cl
H CH (CHThree) CH2SCHThree               CHF2             Ph-4-Br
H CH (CHThree) CH2SCHThree               CHF2             Ph-4-CFThree
H CH (CHThree) CH2SCHThree               CHF2             Ph-4-OCFThree
H CH (CHThree) CH2SCHThree               CHF2             Ph-4-OCF2Br
H CH (CHThree) CH2SCHThree               CHF2             Ph-4-OCF2CHFCFThree
H CH (CHThree) CH2SCHThree               CHF2             Ph-4-OCF2CHFOCFThree
H CH (CHThree) CH2SCHThree               CHF2             Ph-4-OCF2CHFOCF2CF2CFThree
H CH (CHThree) CH2SCHThree               CHF2             Ph-4-O (L-45g)
H CH (CHThree) CH2SCHThree               CHF2             Ph-3,4-Cl2
H CH (CHThree) CH2SCHThree               CHF2             Ph (-3-OCF2O-4-)
H CH (CHThree) CH2SCHThree               CHF2             Ph (-3-OCF2CF2O-4-)
H CH (CHThree) CH2SCHThree               CHF2            (L-45c) CFThree
H CH (CHThree) CH2SCHThree               CHF2             L-45f
H CH (CHThree) CH2SCHThree               CHF2            (L-46c) CFThree
H CH (CHThree) CH2SCHThree               CHF2             L-46d
H CH (CHThree) CH2SCHThree               CHFCl Ph-4-CFThree
H CH (CHThree) CH2SCHThree               CHFBr Ph-4-OCFThree
H CH (CHThree) CH2SCHThree               CFThree              c-Pr
H CH (CHThree) CH2SCHThree               CFThree              c-Bu
H CH (CHThree) CH2SCHThree               CFThree              c-Pen
H CH (CHThree) CH2SCHThree               CFThree              c-Hex
H CH (CHThree) CH2SCHThree               CFThree              T-1
H CH (CHThree) CH2SCHThree               CFThree              T-2
H CH (CHThree) CH2SCHThree               CFThree              T-3
H CH (CHThree) CH2SCHThree               CFThree              T-4
H CH (CHThree) CH2SCHThree               CFThree              T-5
H CH (CHThree) CH2SCHThree               CFThree              CH2OCHThree
H CH (CHThree) CH2SCHThree               CFThree              CH2OEt
H CH (CHThree) CH2SCHThree               CFThree              CH2OPr-n
H CH (CHThree) CH2SCHThree               CFThree              CH2OPr-i
H CH (CHThree) CH2SCHThree               CFThree              CH2OBu-n
H CH (CHThree) CH2SCHThree               CFThree              CH2OC (O) (Ph-2-Cl)
H CH (CHThree) CH2SCHThree               CFThree              CH2OC (O) (Ph-3-Cl)
H CH (CHThree) CH2SCHThree               CFThree              CH2OC (O) (Ph-4-Cl)
H CH (CHThree) CH2SCHThree               CFThree              CH2OPh
H CH (CHThree) CH2SCHThree               CFThree              CH2O (Ph-2-F)
H CH (CHThree) CH2SCHThree               CFThree              CH2O (Ph-3-F)
H CH (CHThree) CH2SCHThree               CFThree              CH2O (Ph-4-F)
H CH (CHThree) CH2SCHThree               CFThree              CH2O (Ph-2-Cl)
H CH (CHThree) CH2SCHThree               CFThree              CH2O (Ph-3-Cl)
H CH (CHThree) CH2SCHThree               CFThree              CH2O (Ph-4-Cl)
H CH (CHThree) CH2SCHThree               CFThree              CH2O (Ph-2-Br)
H CH (CHThree) CH2SCHThree               CFThree              CH2O (Ph-3-Br)
H CH (CHThree) CH2SCHThree               CFThree              CH2O (Ph-4-Br)
H CH (CHThree) CH2SCHThree               CFThree              CH2O (Ph-2-CFThree)
H CH (CHThree) CH2SCHThree               CFThree              CH2O (Ph-3-CFThree)
H CH (CHThree) CH2SCHThree               CFThree              CH2O (Ph-4-CFThree)
H CH (CHThree) CH2SCHThree               CFThree              CH2O (Ph-2-OCFThree)
H CH (CHThree) CH2SCHThree               CFThree              CH2O (Ph-3-OCFThree)
H CH (CHThree) CH2SCHThree               CFThree              CH2O (Ph-4-OCFThree)
H CH (CHThree) CH2SCHThree               CFThree              CF2OPh
H CH (CHThree) CH2SCHThree               CFThree              CF2O (Ph-2-F)
H CH (CHThree) CH2SCHThree               CFThree              CF2O (Ph-3-F)
H CH (CHThree) CH2SCHThree               CFThree              CF2O (Ph-4-F)
H CH (CHThree) CH2SCHThree               CFThree              CF2O (Ph-2-Cl)
H CH (CHThree) CH2SCHThree               CFThree              CF2O (Ph-3-Cl)
H CH (CHThree) CH2SCHThree               CFThree              CF2O (Ph-4-Cl)
H CH (CHThree) CH2SCHThree               CFThree              CF2O (Ph-2-Br)
H CH (CHThree) CH2SCHThree               CFThree              CF2O (Ph-3-Br)
H CH (CHThree) CH2SCHThree               CFThree              CF2O (Ph-4-Br)
H CH (CHThree) CH2SCHThree               CFThree              CF2O (Ph-2-CFThree)
H CH (CHThree) CH2SCHThree               CFThree              CF2O (Ph-3-CFThree)
H CH (CHThree) CH2SCHThree               CFThree              CF2O (Ph-4-CFThree)
H CH (CHThree) CH2SCHThree               CFThree              CF2O (Ph-2-OCFThree)
H CH (CHThree) CH2SCHThree               CFThree              CF2O (Ph-3-OCFThree)
H CH (CHThree) CH2SCHThree               CFThree              CF2O (Ph-4-OCFThree)
H CH (CHThree) CH2SCHThree               CFThree              CH2S (Ph-2-Cl)
H CH (CHThree) CH2SCHThree               CFThree              CH2S (Ph-3-Cl)
H CH (CHThree) CH2SCHThree               CFThree              CH2S (Ph-4-Cl)
H CH (CHThree) CH2SCHThree               CFThree              CH2SO2(Ph-2-Cl)
H CH (CHThree) CH2SCHThree               CFThree              CH2SO2(Ph-3-Cl)
H CH (CHThree) CH2SCHThree               CFThree              CH2SO2(Ph-4-Cl)
H CH (CHThree) CH2SCHThree               CFThree              CH2N (CHThree)2
H CH (CHThree) CH2SCHThree               CFThree              CH2NH (Ph-2-Cl)
H CH (CHThree) CH2SCHThree               CFThree              CH2NH (Ph-3-Cl)
H CH (CHThree) CH2SCHThree               CFThree              CH2NH (Ph-4-Cl)
H CH (CHThree) CH2SCHThree               CFThree              CF2C (O) OEt
H CH (CHThree) CH2SCHThree               CFThree              CH2(L-5a)
H CH (CHThree) CH2SCHThree               CFThree              CH2(L-14a)
H CH (CHThree) CH2SCHThree               CFThree              CH2(L-24a)
H CH (CHThree) CH2SCHThree               CFThree              CH2(L-36a)
H CH (CHThree) CH2SCHThree               CFThree              CH2CH2Ph
H CH (CHThree) CH2SCHThree               CFThree              CH2CH2(Ph-2-Cl)
H CH (CHThree) CH2SCHThree               CFThree              CH2CH2(Ph-3-Cl)
H CH (CHThree) CH2SCHThree               CFThree              CH2CH2(Ph-4-Cl)
H CH (CHThree) CH2SCHThree               CFThree              T-22
H CH (CHThree) CH2SCHThree               CFThree              T-23
H CH (CHThree) CH2SCHThree               CFThree              T-24
H CH (CHThree) CH2SCHThree               CFThree              C (O) OEt
H CH (CHThree) CH2SCHThree               CFThree              C (O) OBu-t
H CH (CHThree) CH2SCHThree               CFThree              C (O) OCH2CFThree
H CH (CHThree) CH2SCHThree               CFThree              CH = CH (Ph-2-F)
H CH (CHThree) CH2SCHThree               CFThree              CH = CH (Ph-3-F)
H CH (CHThree) CH2SCHThree               CFThree              CH = CH (Ph-4-F)
H CH (CHThree) CH2SCHThree               CFThree              CH = CH (Ph-2-Cl)
H CH (CHThree) CH2SCHThree               CFThree              CH = CH (Ph-3-Cl)
H CH (CHThree) CH2SCHThree               CFThree              CH = CH (Ph-4-Cl)
H CH (CHThree) CH2SCHThree               CFThree              CH = CH (Ph-2-Br)
H CH (CHThree) CH2SCHThree               CFThree              CH = CH (Ph-3-Br)
H CH (CHThree) CH2SCHThree               CFThree              CH = CH (Ph-4-Br)
H CH (CHThree) CH2SCHThree               CFThree              CH = CH (Ph-2-CFThree)
H CH (CHThree) CH2SCHThree               CFThree              CH = CH (Ph-3-CFThree)
H CH (CHThree) CH2SCHThree               CFThree              CH = CH (Ph-4-CFThree)
H CH (CHThree) CH2SCHThree               CFThree              CH = CH (Ph-2-OCFThree)
H CH (CHThree) CH2SCHThree               CFThree              CH = CH (Ph-3-OCFThree)
H CH (CHThree) CH2SCHThree               CFThree              CH = CH (Ph-4-OCFThree)
H CH (CHThree) CH2SCHThree               CFThree              CH = CH (Ph-2-SCHThree)
H CH (CHThree) CH2SCHThree               CFThree              CH = CH (Ph-3-SCHThree)
H CH (CHThree) CH2SCHThree               CFThree              CH = CH (Ph-4-SCHThree)
H CH (CHThree) CH2SCHThree               CFThree              CH = CH (Ph-2-SO2CHThree)
H CH (CHThree) CH2SCHThree               CFThree              CH = CH (Ph-3-SO2CHThree)
H CH (CHThree) CH2SCHThree               CFThree              CH = CH (Ph-4-SO2CHThree)
H CH (CHThree) CH2SCHThree               CFThree              CH = CH (Ph-3,4-F2)
H CH (CHThree) CH2SCHThree               CFThree              CH = CH (Ph-3-F-4-Cl)
H CH (CHThree) CH2SCHThree               CFThree              CH = CH (Ph-3,4-Cl2)
H CH (CHThree) CH2SCHThree               CFThree              CH = CH (Ph-3,4-Br2)
H CH (CHThree) CH2SCHThree               CFThree              CH = CH (Ph-3-F-4-CFThree)
H CH (CHThree) CH2SCHThree               CFThree              CH = CH (Ph-3-Cl-4-OCFThree)
H CH (CHThree) CH2SCHThree               CFThree              CH = CH [Ph (-3-OCF2O-4-)]
H CH (CHThree) CH2SCHThree               CFThree              Ph
H CH (CHThree) CH2SCHThree               CFThree              Ph-2-F
H CH (CHThree) CH2SCHThree               CFThree              Ph-3-F
H CH (CHThree) CH2SCHThree               CFThree              Ph-4-F
H CH (CHThree) CH2SCHThree               CFThree              Ph-2-Cl
H CH (CHThree) CH2SCHThree               CFThree              Ph-3-Cl
H CH (CHThree) CH2SCHThree               CFThree              Ph-4-Cl
H CH (CHThree) CH2SCHThree               CFThree              Ph-2-Br
H CH (CHThree) CH2SCHThree               CFThree              Ph-3-Br
H CH (CHThree) CH2SCHThree               CFThree              Ph-4-Br
H CH (CHThree) CH2SCHThree               CFThree              Ph-4-I
H CH (CHThree) CH2SCHThree               CFThree              Ph-4-Bu-t
H CH (CHThree) CH2SCHThree               CFThree              Ph-2-CFThree
H CH (CHThree) CH2SCHThree               CFThree              Ph-3-CFThree
H CH (CHThree) CH2SCHThree               CFThree              Ph-4-CFThree
H CH (CHThree) CH2SCHThree               CFThree              Ph-4-OCHThree
H CH (CHThree) CH2SCHThree               CFThree              Ph-4-OCHF2
H CH (CHThree) CH2SCHThree               CFThree              Ph-2-OCFThree
H CH (CHThree) CH2SCHThree               CFThree              Ph-3-OCFThree
H CH (CHThree) CH2SCHThree               CFThree              Ph-4-OCFThree
H CH (CHThree) CH2SCHThree(R) CFThree              Ph-4-OCFThree
H CH (CHThree) CH2SCHThree(S) CFThree              Ph-4-OCFThree
H CH (CHThree) CH2SCHThree               CFThree              Ph-4-OCF2Br
H CH (CHThree) CH2SCHThree               CFThree              Ph-4-OCH2CFThree
H CH (CHThree) CH2SCHThree               CFThree              Ph-4-OCF2CHF2
H CH (CHThree) CH2SCHThree               CFThree              Ph-4-OCF2CHFCl
H CH (CHThree) CH2SCHThree               CFThree              Ph-4-OCF2CHFBr
H CH (CHThree) CH2SCHThree               CFThree              Ph-4-OCF2CF2Br
H CH (CHThree) CH2SCHThree               CFThree              Ph-4-OCF2CFCl2
H CH (CHThree) CH2SCHThree               CFThree              Ph-4-OCF2CClThree
H CH (CHThree) CH2SCHThree               CFThree              Ph-4-OCH2CF2CHF2
H CH (CHThree) CH2SCHThree               CFThree              Ph-3-OCF2CHFCFThree
H CH (CHThree) CH2SCHThree               CFThree              Ph-4-OCF2CHFCFThree
H CH (CHThree) CH2SCHThree               CFThree              Ph-4-OCH (CFThree)2
H CH (CHThree) CH2SCHThree               CFThree              Ph-4-OCF2CFBrCFThree
H CH (CHThree) CH2SCHThree               CFThree              Ph-3-OCF2CHFOCFThree
H CH (CHThree) CH2SCHThree               CFThree              Ph-4-OCF2CHFOCFThree
H CH (CHThree) CH2SCHThree               CFThree              Ph-4-OCF2CHFOCF2CF2CFThree
H CH (CHThree) CH2SCHThree               CFThree              Ph-4-OSO2CHThree
H CH (CHThree) CH2SCHThree               CFThree              Ph-4-OSO2CFThree
H CH (CHThree) CH2SCHThree               CFThree              Ph-3-O (Ph-4-Cl)
H CH (CHThree) CH2SCHThree               CFThree              Ph-4-O (Ph-4-Cl)
H CH (CHThree) CH2SCHThree               CFThree              Ph-4-O (Ph-4-Br)
H CH (CHThree) CH2SCHThree               CFThree              Ph-4-O (Ph-4-CFThree)
H CH (CHThree) CH2SCHThree               CFThree              Ph-4-O (L-45c) Br
H CH (CHThree) CH2SCHThree               CFThree              Ph-4-O (L-45c) CFThree
H CH (CHThree) CH2SCHThree               CFThree              Ph-3-O (L-45e)
H CH (CHThree) CH2SCHThree               CFThree              Ph-4-O (L-45e)
H CH (CHThree) CH2SCHThree               CFThree              Ph-4-O (L-48b) Br
H CH (CHThree) CH2SCHThree               CFThree              Ph-4-SCHThree
H CH (CHThree) CH2SCHThree               CFThree              Ph-4-SO2CHThree
H CH (CHThree) CH2SCHThree               CFThree              Ph-3-S (Ph-4-Cl)
H CH (CHThree) CH2SCHThree               CFThree              Ph-4-S (Ph-4-Cl)
H CH (CHThree) CH2SCHThree               CFThree              Ph-4-S (Ph-4-Br)
H CH (CHThree) CH2SCHThree               CFThree              Ph-4-S (Ph-4-CFThree)
H CH (CHThree) CH2SCHThree               CFThree              Ph-4-S (L-45c) Br
H CH (CHThree) CH2SCHThree               CFThree              Ph-4-S (L-45c) CFThree
H CH (CHThree) CH2SCHThree               CFThree              Ph-4-S (L-45e)
H CH (CHThree) CH2SCHThree               CFThree              Ph-4-S (L-48b) Br
H CH (CHThree) CH2SCHThree               CFThree              Ph-4-NO2
H CH (CHThree) CH2SCHThree               CFThree              Ph-4-CN
H CH (CHThree) CH2SCHThree               CFThree              Ph-2,3-F2
H CH (CHThree) CH2SCHThree               CFThree              Ph-2,4-F2
H CH (CHThree) CH2SCHThree               CFThree              Ph-3,4-F2
H CH (CHThree) CH2SCHThree               CFThree              Ph-2,5-F2
H CH (CHThree) CH2SCHThree               CFThree              Ph-3,5-F2
H CH (CHThree) CH2SCHThree               CFThree              Ph-2-Cl-4-F
H CH (CHThree) CH2SCHThree               CFThree              Ph-2-F-3-Cl
H CH (CHThree) CH2SCHThree               CFThree              Ph-3-Cl-4-F
H CH (CHThree) CH2SCHThree               CFThree              Ph-2-F-4-Cl
H CH (CHThree) CH2SCHThree               CFThree              Ph-3-F-4-Cl
H CH (CHThree) CH2SCHThree               CFThree              Ph-2,3-Cl2
H CH (CHThree) CH2SCHThree               CFThree              Ph-2,4-Cl2
H CH (CHThree) CH2SCHThree               CFThree              Ph-2,5-Cl2
H CH (CHThree) CH2SCHThree               CFThree              Ph-3,4-Cl2
H CH (CHThree) CH2SCHThree               CFThree              Ph-3,5-Cl2
H CH (CHThree) CH2SCHThree               CFThree              Ph-3-Br-4-F
H CH (CHThree) CH2SCHThree               CFThree              Ph-2-F-4-Br
H CH (CHThree) CH2SCHThree               CFThree              Ph-2-F-5-Br
H CH (CHThree) CH2SCHThree               CFThree              Ph-3,4-Br2
H CH (CHThree) CH2SCHThree               CFThree              Ph-3,5-Br2
H CH (CHThree) CH2SCHThree               CFThree              Ph-3-CHThree-4-F
H CH (CHThree) CH2SCHThree               CFThree              Ph-3-F-4-CHThree
H CH (CHThree) CH2SCHThree               CFThree              Ph-2-F-5-CHThree
H CH (CHThree) CH2SCHThree               CFThree              Ph-2,4- (CHThree)2
H CH (CHThree) CH2SCHThree               CFThree              Ph-3,4- (CHThree)2
H CH (CHThree) CH2SCHThree               CFThree              Ph-2-F-3-CFThree
H CH (CHThree) CH2SCHThree               CFThree              Ph-3-CFThree-4-F
H CH (CHThree) CH2SCHThree               CFThree              Ph-3-CFThree-4-Cl
H CH (CHThree) CH2SCHThree               CFThree              Ph-2-F-4-CFThree
H CH (CHThree) CH2SCHThree               CFThree              Ph-3-F-4-CFThree
H CH (CHThree) CH2SCHThree               CFThree              Ph-2-F-5-CFThree
H CH (CHThree) CH2SCHThree               CFThree              Ph-3-F-5-CFThree
H CH (CHThree) CH2SCHThree               CFThree              Ph-2-Cl-4-CFThree
H CH (CHThree) CH2SCHThree               CFThree              Ph-3,5- (CFThree)2
H CH (CHThree) CH2SCHThree               CFThree              Ph-3-Br-4-OCHThree
H CH (CHThree) CH2SCHThree               CFThree              Ph-3-F-4-OCHF2
H CH (CHThree) CH2SCHThree               CFThree              Ph-3-Cl-4-OCHF2
H CH (CHThree) CH2SCHThree               CFThree              Ph-3-Br-4-OCHF2
H CH (CHThree) CH2SCHThree               CFThree              Ph-3-F-4-OCFThree
H CH (CHThree) CH2SCHThree               CFThree              Ph-3-Cl-4-OCFThree
H CH (CHThree) CH2SCHThree               CFThree              Ph-3-Br-4-OCFThree
H CH (CHThree) CH2SCHThree               CFThree              Ph-3-F-4-OCF2Br
H CH (CHThree) CH2SCHThree               CFThree              Ph-3-Cl-4-OCF2Br
H CH (CHThree) CH2SCHThree               CFThree              Ph-3-Br-4-OCF2Br
H CH (CHThree) CH2SCHThree               CFThree              Ph-3-F-4-OCF2CHF2
H CH (CHThree) CH2SCHThree               CFThree              Ph-3-Cl-4-OCF2CHF2
H CH (CHThree) CH2SCHThree               CFThree              Ph-3-Br-4-OCF2CHF2
H CH (CHThree) CH2SCHThree               CFThree              Ph-3-F-4-OCF2CHFCl
H CH (CHThree) CH2SCHThree               CFThree              Ph-3-Cl-4-OCF2CHFCl
H CH (CHThree) CH2SCHThree               CFThree              Ph-3-Br-4-OCF2CHFCl
H CH (CHThree) CH2SCHThree               CFThree              Ph-3-F-4-OCF2CHFCFThree
H CH (CHThree) CH2SCHThree               CFThree              Ph-3-Cl-4-OCF2CHFCFThree
H CH (CHThree) CH2SCHThree               CFThree              Ph-3-Br-4-OCF2CHFCFThree
H CH (CHThree) CH2SCHThree               CFThree              Ph-3-F-4-OCF2CHFOCFThree
H CH (CHThree) CH2SCHThree               CFThree              Ph-3-Cl-4-OCF2CHFOCFThree
H CH (CHThree) CH2SCHThree               CFThree              Ph-3-Br-4-OCF2CHFOCFThree
H CH (CHThree) CH2SCHThree               CFThree              Ph-3-CHThree-4-OCF2CHFOCFThree
H CH (CHThree) CH2SCHThree               CFThree         Ph-3-F-4-OCF2CHFOCF2CF2CFThree
H CH (CHThree) CH2SCHThree               CFThree         Ph-3-Cl-4-OCF2CHFOCF2CF2CFThree
H CH (CHThree) CH2SCHThree               CFThree         Ph-3-Br-4-OCF2CHFOCF2CF2CFThree
H CH (CHThree) CH2SCHThree               CFThree              Ph (-3-OCF2O-4-)
H CH (CHThree) CH2SCHThree               CFThree              Ph (-3-OCF2CF2O-4-)
H CH (CHThree) CH2SCHThree               CFThree              Ph-3-OPh-4-F
H CH (CHThree) CH2SCHThree               CFThree              Ph-3-NO2-4-F
H CH (CHThree) CH2SCHThree               CFThree              Ph-3-NO2-4-Cl
H CH (CHThree) CH2SCHThree               CFThree              Ph-2-F-5-NO2
H CH (CHThree) CH2SCHThree               CFThree              Ph-3-CN-4-F
H CH (CHThree) CH2SCHThree               CFThree              Ph-2,3,4-FThree
H CH (CHThree) CH2SCHThree               CFThree              Ph-2,3,5-FThree
H CH (CHThree) CH2SCHThree               CFThree              Ph-2,4,5-FThree
H CH (CHThree) CH2SCHThree               CFThree              Ph-3,4,5-FThree
H CH (CHThree) CH2SCHThree               CFThree              Ph-2,3-F2-4-CHThree
H CH (CHThree) CH2SCHThree               CFThree              Ph-2,3-F2-4-CFThree
H CH (CHThree) CH2SCHThree               CFThree              Ph-3,4-F2-5-CFThree
H CH (CHThree) CH2SCHThree               CFThree              Ph-2-F-3-Cl-5-CFThree
H CH (CHThree) CH2SCHThree               CFThree              Ph-3,5-Cl2-4-OCHThree
H CH (CHThree) CH2SCHThree               CFThree              1-Naph
H CH (CHThree) CH2SCHThree               CFThree              2-Naph
H CH (CHThree) CH2SCHThree               CFThree             (L-1b) Br
H CH (CHThree) CH2SCHThree               CFThree             (L-1c) Cl
H CH (CHThree) CH2SCHThree               CFThree             (L-1c) Br
H CH (CHThree) CH2SCHThree               CFThree             (L-1c) I
H CH (CHThree) CH2SCHThree               CFThree             (L-1c) CFThree
H CH (CHThree) CH2SCHThree               CFThree             (L-2b) Br
H CH (CHThree) CH2SCHThree               CFThree             (L-3b) Cl
H CH (CHThree) CH2SCHThree               CFThree             (L-3b) Br
H CH (CHThree) CH2SCHThree               CFThree             (L-3c) F
H CH (CHThree) CH2SCHThree               CFThree             (L-3c) Cl
H CH (CHThree) CH2SCHThree               CFThree             (L-3c) Br
H CH (CHThree) CH2SCHThree               CFThree             (L-3c) I
H CH (CHThree) CH2SCHThree               CFThree             (L-3c) CFThree
H CH (CHThree) CH2SCHThree               CFThree             (L-3c) CN
H CH (CHThree) CH2SCHThree               CFThree              L-3d
H CH (CHThree) CH2SCHThree               CFThree             (L-4b) Cl
H CH (CHThree) CH2SCHThree               CFThree             (L-4b) Br
H CH (CHThree) CH2SCHThree               CFThree             (L-4b) CN
H CH (CHThree) CH2SCHThree               CFThree             (L-10b) Cl
H CH (CHThree) CH2SCHThree               CFThree             (L-10b) Br
H CH (CHThree) CH2SCHThree               CFThree             (L-15b) CFThree
H CH (CHThree) CH2SCHThree               CFThree             (L-16a) CHF2
H CH (CHThree) CH2SCHThree               CFThree             (L-16a) CF2Br
H CH (CHThree) CH2SCHThree               CFThree             (L-17a) Cl
H CH (CHThree) CH2SCHThree               CFThree             (L-21b) Cl
H CH (CHThree) CH2SCHThree               CFThree             (L-21b) Br
H CH (CHThree) CH2SCHThree               CFThree             (L-21b) I
H CH (CHThree) CH2SCHThree               CFThree             (L-21b) CFThree
H CH (CHThree) CH2SCHThree               CFThree             (L-22b) Cl
H CH (CHThree) CH2SCHThree               CFThree             (L-22b) Br
H CH (CHThree) CH2SCHThree               CFThree             (L-23b) Cl
H CH (CHThree) CH2SCHThree               CFThree             (L-23b) Br
H CH (CHThree) CH2SCHThree               CFThree             (L-23c) Cl
H CH (CHThree) CH2SCHThree               CFThree             (L-23c) Br
H CH (CHThree) CH2SCHThree               CFThree             (L-31a) Cl
H CH (CHThree) CH2SCHThree               CFThree             (L-31a) Br
H CH (CHThree) CH2SCHThree               CFThree             (L-45c) F
H CH (CHThree) CH2SCHThree               CFThree             (L-45c) Cl
H CH (CHThree) CH2SCHThree               CFThree             (L-45c) Br
H CH (CHThree) CH2SCHThree               CFThree             (L-45c) I
H CH (CHThree) CH2SCHThree               CFThree             (L-45c) CFThree
H CH (CHThree) CH2SCHThree               CFThree              L-45e
H CH (CHThree) CH2SCHThree               CFThree              L-45f
H CH (CHThree) CH2SCHThree               CFThree             (L-46c) F
H CH (CHThree) CH2SCHThree               CFThree             (L-46c) Cl
H CH (CHThree) CH2SCHThree               CFThree             (L-46c) Br
H CH (CHThree) CH2SCHThree               CFThree             (L-46c) I
H CH (CHThree) CH2SCHThree               CFThree             (L-46c) CFThree
H CH (CHThree) CH2SCHThree               CFThree             (L-46c) OCH2CFThree
H CH (CHThree) CH2SCHThree               CFThree             (L-46c) OCH (CFThree)2
H CH (CHThree) CH2SCHThree               CFThree              L-46d
H CH (CHThree) CH2SCHThree               CFThree              L-47a
H CH (CHThree) CH2SCHThree               CFThree              L-47d
H CH (CHThree) CH2SCHThree               CFThree             (L-48b) Br
H CH (CHThree) CH2SCHThree               CFThree             (L-50b) Cl
H CH (CHThree) CH2SCHThree               CFThree             (L-50b) Br
H CH (CHThree) CH2SCHThree               CFThree             (L-51b) Cl
H CH (CHThree) CH2SCHThree               CF2Cl Ph-4-Cl
H CH (CHThree) CH2SCHThree               CF2Cl Ph-4-Br
H CH (CHThree) CH2SCHThree               CF2Cl Ph-4-CFThree
H CH (CHThree) CH2SCHThree               CF2Cl Ph-4-OCFThree
H CH (CHThree) CH2SCHThree               CF2Cl Ph-4-OCF2Br
H CH (CHThree) CH2SCHThree               CF2Cl Ph-4-OCF2CHFCFThree
H CH (CHThree) CH2SCHThree               CF2Cl Ph-4-OCF2CHFOCFThree
H CH (CHThree) CH2SCHThree               CF2Cl Ph-4-OCF2CHFOCF2CF2CFThree
H CH (CHThree) CH2SCHThree               CF2Cl Ph-4-O (L-45g)
H CH (CHThree) CH2SCHThree               CF2Cl Ph-3,4-Cl2
H CH (CHThree) CH2SCHThree               CF2Cl Ph (-3-OCF2O-4-)
H CH (CHThree) CH2SCHThree               CF2Cl Ph (-3-OCF2CF2O-4-)
H CH (CHThree) CH2SCHThree               CF2Cl (L-45c) CFThree
H CH (CHThree) CH2SCHThree               CF2Cl L-45f
H CH (CHThree) CH2SCHThree               CF2Cl (L-46c) CFThree
H CH (CHThree) CH2SCHThree               CF2Cl L-46d
H CH (CHThree) CH2SCHThree               CFCl2           (L-45c) CFThree
H CH (CHThree) CH2SCHThree               CF2Br Ph-4-Cl
H CH (CHThree) CH2SCHThree               CF2Br Ph-4-Br
H CH (CHThree) CH2SCHThree               CF2Br Ph-4-CFThree
H CH (CHThree) CH2SCHThree               CF2Br Ph-4-OCFThree
H CH (CHThree) CH2SCHThree               CF2Br Ph-4-OCF2Br
H CH (CHThree) CH2SCHThree               CF2Br Ph-4-OCF2CHFCFThree
H CH (CHThree) CH2SCHThree               CF2Br Ph-4-OCF2CHFOCFThree
H CH (CHThree) CH2SCHThree               CF2Br Ph-4-OCF2CHFOCF2CF2CFThree
H CH (CHThree) CH2SCHThree               CF2Br Ph-4-O (L-45g)
H CH (CHThree) CH2SCHThree               CF2Br Ph-3,4-Cl2
H CH (CHThree) CH2SCHThree               CF2Br Ph (-3-OCF2O-4-)
H CH (CHThree) CH2SCHThree               CF2Br Ph (-3-OCF2CF2O-4-)
H CH (CHThree) CH2SCHThree               CF2Br (L-45c) CFThree
H CH (CHThree) CH2SCHThree               CF2Br L-45f
H CH (CHThree) CH2SCHThree               CF2Br (L-46c) CFThree
H CH (CHThree) CH2SCHThree               CF2Br L-46d
H CH (CHThree) CH2SCHThree               CFClBr Ph-4-Br
H CH (CHThree) CH2SCHThree               CFBr2            Ph-4-CFThree
H CH (CHThree) CH2SCHThree               CF2CHF2          Ph-4-OCFThree
H CH (CHThree) CH2SCHThree               CF2CFThree           Ph-4-Cl
H CH (CHThree) CH2SCHThree               CF2CFThree           Ph-4-Br
H CH (CHThree) CH2SCHThree               CF2CFThree           Ph-4-CFThree
H CH (CHThree) CH2SCHThree               CF2CFThree           Ph-4-OCFThree
H CH (CHThree) CH2SCHThree               CF2CFThree           Ph-4-OCF2Br
H CH (CHThree) CH2SCHThree               CF2CFThree           Ph-4-OCF2CHFCFThree
H CH (CHThree) CH2SCHThree               CF2CFThree           Ph-4-OCF2CHFOCFThree
H CH (CHThree) CH2SCHThree               CF2CFThree           Ph-4-OCF2CHFOCF2CF2CFThree
H CH (CHThree) CH2SCHThree               CF2CFThree           Ph-4-O (L-45g)
H CH (CHThree) CH2SCHThree               CF2CFThree           Ph-3,4-Cl2
H CH (CHThree) CH2SCHThree               CF2CFThree           Ph (-3-OCF2O-4-)
H CH (CHThree) CH2SCHThree               CF2CFThree           Ph (-3-OCF2CF2O-4-)
H CH (CHThree) CH2SCHThree               CF2CFThree          (L-45c) CFThree
H CH (CHThree) CH2SCHThree               CF2CFThree           L-45f
H CH (CHThree) CH2SCHThree               CF2CFThree          (L-46c) CFThree
H CH (CHThree) CH2SCHThree               CF2CFThree           L-46d
H CH (CHThree) CH2SCHThree               CF2CF2Cl (L-45c) CFThree
H CH (CHThree) CH2SCHThree               CFClCFThree          Ph-4-Br
H CH (CHThree) CH2SCHThree               CFClCF2Cl Ph-4-CFThree
H CH (CHThree) CH2SCHThree               CF2CF2Br Ph-4-OCFThree
H CH (CHThree) CH2SCHThree               CFBrCFThree         (L-45c) CFThree
H CH (CHThree) CH2SCHThree               CF2CHFCFThree        Ph-4-Br
H CH (CHThree) CH2SCHThree               CF2CF2CFThree        Ph-4-Cl
H CH (CHThree) CH2SCHThree               CF2CF2CFThree        Ph-4-Br
H CH (CHThree) CH2SCHThree               CF2CF2CFThree        Ph-4-CFThree
H CH (CHThree) CH2SCHThree               CF2CF2CFThree        Ph-4-OCFThree
H CH (CHThree) CH2SCHThree               CF2CF2CFThree        Ph-4-OCF2Br
H CH (CHThree) CH2SCHThree               CF2CF2CFThree        Ph-4-OCF2CHFCFThree
H CH (CHThree) CH2SCHThree               CF2CF2CFThree        Ph-4-OCF2CHFOCFThree
H CH (CHThree) CH2SCHThree               CF2CF2CFThree        Ph-4-OCF2CHFOCF2CF2CFThree
H CH (CHThree) CH2SCHThree               CF2CF2CFThree        Ph-4-O (L-45g)
H CH (CHThree) CH2SCHThree               CF2CF2CFThree        Ph-3,4-Cl2
H CH (CHThree) CH2SCHThree               CF2CF2CFThree        Ph (-3-OCF2O-4-)
H CH (CHThree) CH2SCHThree               CF2CF2CFThree        Ph (-3-OCF2CF2O-4-)
H CH (CHThree) CH2SCHThree               CF2CF2CFThree       (L-45c) CFThree
H CH (CHThree) CH2SCHThree               CF2CF2CFThree        L-45f
H CH (CHThree) CH2SCHThree               CF2CF2CFThree       (L-46c) CFThree
H CH (CHThree) CH2SCHThree               CF2CF2CFThree        L-46d
H CH (CHThree) CH2SCHThree               CF (CFThree)2         Ph-4-CFThree
H CH (CHThree) CH2SCHThree               CF2CF2CF2CFThree     Ph-4-OCFThree
H CH (CHThree) CH2SCHThree               T-1 (L-45c) CFThree
H CH (CHThree) CH2SCHThree               T-2 Ph-4-Br
H CH (CHThree) CH2SCHThree               CH2OCHThree          Ph-4-CFThree
H CH (CHThree) CH2SCHThree               CH2OEt Ph-4-OCFThree
H CH (CHThree) CH2SCHThree               CH2OCH2CFThree      (L-45c) CFThree
H CH (CHThree) CH2SCHThree               CH2OCH (CFThree)2     Ph-4-Br
H CH (CHThree) CH2SCHThree               CF2OCHThree          Ph-4-Cl
H CH (CHThree) CH2SCHThree               CF2OCHThree          Ph-4-Br
H CH (CHThree) CH2SCHThree               CF2OCHThree          Ph-4-CFThree
H CH (CHThree) CH2SCHThree               CF2OCHThree          Ph-4-OCFThree
H CH (CHThree) CH2SCHThree               CF2OCHThree          Ph-4-OCF2Br
H CH (CHThree) CH2SCHThree               CF2OCHThree          Ph-4-OCF2CHFCFThree
H CH (CHThree) CH2SCHThree               CF2OCHThree          Ph-4-OCF2CHFOCFThree
H CH (CHThree) CH2SCHThree               CF2OCHThree          Ph-4-OCF2CHFOCF2CF2CFThree
H CH (CHThree) CH2SCHThree               CF2OCHThree          Ph-4-O (L-45g)
H CH (CHThree) CH2SCHThree               CF2OCHThree          Ph-3,4-Cl2
H CH (CHThree) CH2SCHThree               CF2OCHThree          Ph (-3-OCF2O-4-)
H CH (CHThree) CH2SCHThree               CF2OCHThree          Ph (-3-OCF2CF2O-4-)
H CH (CHThree) CH2SCHThree               CF2OCHThree         (L-45c) CFThree
H CH (CHThree) CH2SCHThree               CF2OCHThree          L-45f
H CH (CHThree) CH2SCHThree               CF2OCHThree         (L-46c) CFThree
H CH (CHThree) CH2SCHThree               CF2OCHThree          L-46d
H CH (CHThree) CH2SCHThree               CH2SCHThree          Ph-4-CFThree
H CH (CHThree) CH2SCHThree               CH2SO2CHThree        Ph-4-OCFThree
H CH (CHThree) CH2SCHThree               CH2SCFThree         (L-45c) CFThree
H CH (CHThree) CH2SCHThree               CF2SCHThree          Ph-4-Cl
H CH (CHThree) CH2SCHThree               CF2SCHThree          Ph-4-Br
H CH (CHThree) CH2SCHThree               CF2SCHThree          Ph-4-CFThree
H CH (CHThree) CH2SCHThree               CF2SCHThree          Ph-4-OCFThree
H CH (CHThree) CH2SCHThree               CF2SCHThree          Ph-4-OCF2Br
H CH (CHThree) CH2SCHThree               CF2SCHThree          Ph-4-OCF2CHFCFThree
H CH (CHThree) CH2SCHThree               CF2SCHThree          Ph-4-OCF2CHFOCFThree
H CH (CHThree) CH2SCHThree               CF2SCHThree          Ph-4-OCF2CHFOCF2CF2CFThree
H CH (CHThree) CH2SCHThree               CF2SCHThree          Ph-4-O (L-45g)
H CH (CHThree) CH2SCHThree               CF2SCHThree          Ph-3,4-Cl2
H CH (CHThree) CH2SCHThree               CF2SCHThree          Ph (-3-OCF2O-4-)
H CH (CHThree) CH2SCHThree               CF2SCHThree          Ph (-3-OCF2CF2O-4-)
H CH (CHThree) CH2SCHThree               CF2SCHThree         (L-45c) CFThree
H CH (CHThree) CH2SCHThree               CF2SCHThree          L-45f
H CH (CHThree) CH2SCHThree               CF2SCHThree         (L-46c) CFThree
H CH (CHThree) CH2SCHThree               CF2SCHThree          L-46d
H CH (CHThree) CH2SCHThree               CF2SEt Ph-4-Br
H CH (CHThree) CH2SCHThree               CF2SPr-n Ph-4-CFThree
H CH (CHThree) CH2SCHThree               CF2SPr-i Ph-4-OCFThree
H CH (CHThree) CH2SCHThree               CF2SCH2Ph (L-45c) CFThree
H CH (CHThree) CH2SCHThree               CF2SPh Ph-4-Br
H CH (CHThree) CH2SCHThree               CF2C (O) OEt Ph-4-CFThree 
H CH (CHThree) CH2SCHThree               CF2SO2N (CHThree)2    Ph-4-OCFThree
H CH (CHThree) CH2SCHThree               C (O) OEt (L-45c) CFThree
H CH (CHThree) CH2SCHThree               C (O) SEt Ph-4-Br
CHThree       CH (CHThree) CH2SCHThree               CFThree              Ph-4-CFThree
Et CH (CHThree) CH2SCHThree               CFThree              Ph-4-OCFThree
H CH (CHThree) CH2S (O) CHThree            CHThree              Ph-4-Br
H CH (CHThree) CH2S (O) CHThree            CHThree              Ph-4-CFThree
H CH (CHThree) CH2S (O) CHThree            CHThree              Ph-4-OCFThree
H CH (CHThree) CH2S (O) CHThree            CHThree             (L-45c) CFThree
H CH (CHThree) CH2S (O) CHThree            CFThree              CH2O (Ph-4-Cl)
H CH (CHThree) CH2S (O) CHThree            CFThree              CH2O (Ph-4-Br)
H CH (CHThree) CH2S (O) CHThree            CFThree              CH2O (Ph-4-CFThree)
H CH (CHThree) CH2S (O) CHThree            CFThree              CH2O (Ph-4-OCFThree)
H CH (CHThree) CH2S (O) CHThree            CFThree              CF2O (Ph-4-Cl)
H CH (CHThree) CH2S (O) CHThree            CFThree              CF2O (Ph-4-Br)
H CH (CHThree) CH2S (O) CHThree            CFThree              CF2O (Ph-4-CFThree)
H CH (CHThree) CH2S (O) CHThree            CFThree              CF2O (Ph-4-OCFThree)
H CH (CHThree) CH2S (O) CHThree            CFThree              CH = CH (Ph-4-F)
H CH (CHThree) CH2S (O) CHThree            CFThree              CH = CH (Ph-4-Cl)
H CH (CHThree) CH2S (O) CHThree            CFThree              CH = CH (Ph-4-Br)
H CH (CHThree) CH2S (O) CHThree            CFThree              CH = CH (Ph-4-CFThree)
H CH (CHThree) CH2S (O) CHThree            CFThree              CH = CH (Ph-4-OCFThree)
H CH (CHThree) CH2S (O) CHThree            CFThree              CH = CH (Ph-4-SCHThree)
H CH (CHThree) CH2S (O) CHThree            CFThree              CH = CH (Ph-4-SO2CHThree)
H CH (CHThree) CH2S (O) CHThree            CFThree              CH = CH (Ph-3,4-Cl2)
H CH (CHThree) CH2S (O) CHThree            CFThree              Ph-4-F
H CH (CHThree) CH2S (O) CHThree            CFThree              Ph-2-Cl
H CH (CHThree) CH2S (O) CHThree            CFThree              Ph-3-Cl
H CH (CHThree) CH2S (O) CHThree            CFThree              Ph-4-Cl
H CH (CHThree) CH2S (O) CHThree            CFThree              Ph-4-Br
H CH (CHThree) CH2S (O) CHThree            CFThree              Ph-4-I
H CH (CHThree) CH2S (O) CHThree            CFThree              Ph-4-CFThree
H CH (CHThree) CH2S (O) CHThree            CFThree              Ph-4-OCHF2
H CH (CHThree) CH2S (O) CHThree            CFThree              Ph-4-OCFThree
H CH (CHThree) CH2S (O) CHThree            CFThree              Ph-4-OCF2Br
H CH (CHThree) CH2S (O) CHThree            CFThree              Ph-4-OCH2CFThree
H CH (CHThree) CH2S (O) CHThree            CFThree              Ph-4-OCF2CHF2
H CH (CHThree) CH2S (O) CHThree            CFThree              Ph-4-OCF2CHFCl
H CH (CHThree) CH2S (O) CHThree            CFThree              Ph-4-OCF2CHFCFThree
H CH (CHThree) CH2S (O) CHThree            CFThree              Ph-4-OCF2CHFOCFThree
H CH (CHThree) CH2S (O) CHThree            CFThree              Ph-4-OCF2CHFOCF2CF2CFThree
H CH (CHThree) CH2S (O) CHThree            CFThree              Ph-4-OSO2CHThree
H CH (CHThree) CH2S (O) CHThree            CFThree              Ph-4-OSO2CFThree
H CH (CHThree) CH2S (O) CHThree            CFThree              Ph-4-O (L-45e)
H CH (CHThree) CH2S (O) CHThree            CFThree              Ph-2,4-F2
H CH (CHThree) CH2S (O) CHThree            CFThree              Ph-3,4-F2
H CH (CHThree) CH2S (O) CHThree            CFThree              Ph-3-Cl-4-F
H CH (CHThree) CH2S (O) CHThree            CFThree              Ph-2-F-4-Cl
H CH (CHThree) CH2S (O) CHThree            CFThree              Ph-3-F-4-Cl
H CH (CHThree) CH2S (O) CHThree            CFThree              Ph-2,4-Cl2
H CH (CHThree) CH2S (O) CHThree            CFThree              Ph-3,4-Cl2
H CH (CHThree) CH2S (O) CHThree            CFThree              Ph-3,5-Cl2
H CH (CHThree) CH2S (O) CHThree            CFThree              Ph-3-Br-4-F
H CH (CHThree) CH2S (O) CHThree            CFThree              Ph-2-F-4-Br
H CH (CHThree) CH2S (O) CHThree            CFThree              Ph-3,4-Br2
H CH (CHThree) CH2S (O) CHThree            CFThree              Ph-3-CHThree-4-F
H CH (CHThree) CH2S (O) CHThree            CFThree              Ph-3-CFThree-4-F
H CH (CHThree) CH2S (O) CHThree            CFThree              Ph-3-CFThree-4-Cl
H CH (CHThree) CH2S (O) CHThree            CFThree              Ph-2-F-4-CFThree
H CH (CHThree) CH2S (O) CHThree            CFThree              Ph-3-F-4-CFThree
H CH (CHThree) CH2S (O) CHThree            CFThree              Ph-2-Cl-4-CFThree
H CH (CHThree) CH2S (O) CHThree            CFThree              Ph-3-F-4-OCHF2
H CH (CHThree) CH2S (O) CHThree            CFThree              Ph-3-Cl-4-OCHF2
H CH (CHThree) CH2S (O) CHThree            CFThree              Ph-3-Br-4-OCHF2
H CH (CHThree) CH2S (O) CHThree            CFThree              Ph-3-F-4-OCFThree
H CH (CHThree) CH2S (O) CHThree            CFThree              Ph-3-Cl-4-OCFThree
H CH (CHThree) CH2S (O) CHThree            CFThree              Ph-3-Br-4-OCFThree
H CH (CHThree) CH2S (O) CHThree            CFThree              Ph-3-F-4-OCF2Br
H CH (CHThree) CH2S (O) CHThree            CFThree              Ph-3-Cl-4-OCF2Br
H CH (CHThree) CH2S (O) CHThree            CFThree              Ph-3-Br-4-OCF2Br
H CH (CHThree) CH2S (O) CHThree            CFThree              Ph-3-F-4-OCF2CHF2
H CH (CHThree) CH2S (O) CHThree            CFThree              Ph-3-Cl-4-OCF2CHF2
H CH (CHThree) CH2S (O) CHThree            CFThree              Ph-3-Br-4-OCF2CHF2
H CH (CHThree) CH2S (O) CHThree            CFThree              Ph-3-F-4-OCF2CHFCl
H CH (CHThree) CH2S (O) CHThree            CFThree              Ph-3-Cl-4-OCF2CHFCl
H CH (CHThree) CH2S (O) CHThree            CFThree              Ph-3-Br-4-OCF2CHFCl
H CH (CHThree) CH2S (O) CHThree            CFThree              Ph-3-F-4-OCF2CHFCFThree
H CH (CHThree) CH2S (O) CHThree            CFThree              Ph-3-Cl-4-OCF2CHFCFThree
H CH (CHThree) CH2S (O) CHThree            CFThree              Ph-3-Br-4-OCF2CHFCFThree
H CH (CHThree) CH2S (O) CHThree            CFThree              Ph-3-F-4-OCF2CHFOCFThree
H CH (CHThree) CH2S (O) CHThree            CFThree              Ph-3-Cl-4-OCF2CHFOCFThree
H CH (CHThree) CH2S (O) CHThree            CFThree              Ph-3-Br-4-OCF2CHFOCFThree
H CH (CHThree) CH2S (O) CHThree            CFThree              Ph-3-CHThree-4-OCF2CHFOCFThree
H CH (CHThree) CH2S (O) CHThree            CFThree         Ph-3-F-4-OCF2CHFOCF2CF2CFThree
H CH (CHThree) CH2S (O) CHThree            CFThree         Ph-3-Cl-4-OCF2CHFOCF2CF2CFThree
H CH (CHThree) CH2S (O) CHThree            CFThree         Ph-3-Br-4-OCF2CHFOCF2CF2CFThree
H CH (CHThree) CH2S (O) CHThree            CFThree              Ph (-3-OCF2O-4-)
H CH (CHThree) CH2S (O) CHThree            CFThree              Ph (-3-OCF2CF2O-4-)
H CH (CHThree) CH2S (O) CHThree            CFThree              Ph-3,4-F2-5-CFThree
H CH (CHThree) CH2S (O) CHThree            CFThree              2-Naph
H CH (CHThree) CH2S (O) CHThree            CFThree             (L-1b) Br
H CH (CHThree) CH2S (O) CHThree            CFThree             (L-1c) Cl
H CH (CHThree) CH2S (O) CHThree            CFThree             (L-1c) Br
H CH (CHThree) CH2S (O) CHThree            CFThree             (L-1c) CFThree
H CH (CHThree) CH2S (O) CHThree            CFThree             (L-2b) Br
H CH (CHThree) CH2S (O) CHThree            CFThree             (L-3b) Cl
H CH (CHThree) CH2S (O) CHThree            CFThree             (L-3b) Br
H CH (CHThree) CH2S (O) CHThree            CFThree             (L-3c) Cl
H CH (CHThree) CH2S (O) CHThree            CFThree             (L-3c) Br
H CH (CHThree) CH2S (O) CHThree            CFThree             (L-3c) CFThree
H CH (CHThree) CH2S (O) CHThree            CFThree              L-3d
H CH (CHThree) CH2S (O) CHThree            CFThree             (L-4b) Cl
H CH (CHThree) CH2S (O) CHThree            CFThree             (L-4b) Br
H CH (CHThree) CH2S (O) CHThree            CFThree             (L-10b) Cl
H CH (CHThree) CH2S (O) CHThree            CFThree             (L-10b) Br
H CH (CHThree) CH2S (O) CHThree            CFThree             (L-15b) CFThree
H CH (CHThree) CH2S (O) CHThree            CFThree             (L-16a) CHF2
H CH (CHThree) CH2S (O) CHThree            CFThree             (L-16a) CF2Br
H CH (CHThree) CH2S (O) CHThree            CFThree             (L-17a) Cl
H CH (CHThree) CH2S (O) CHThree            CFThree             (L-21b) Cl
H CH (CHThree) CH2S (O) CHThree            CFThree             (L-21b) Br
H CH (CHThree) CH2S (O) CHThree            CFThree             (L-21b) CFThree
H CH (CHThree) CH2S (O) CHThree            CFThree             (L-22b) Cl
H CH (CHThree) CH2S (O) CHThree            CFThree             (L-22b) Br
H CH (CHThree) CH2S (O) CHThree            CFThree             (L-23b) Cl
H CH (CHThree) CH2S (O) CHThree            CFThree             (L-23b) Br
H CH (CHThree) CH2S (O) CHThree            CFThree             (L-23c) Cl
H CH (CHThree) CH2S (O) CHThree            CFThree             (L-23c) Br
H CH (CHThree) CH2S (O) CHThree            CFThree             (L-31a) Cl
H CH (CHThree) CH2S (O) CHThree            CFThree             (L-31a) Br
H CH (CHThree) CH2S (O) CHThree            CFThree             (L-45c) F
H CH (CHThree) CH2S (O) CHThree            CFThree             (L-45c) Cl
H CH (CHThree) CH2S (O) CHThree            CFThree             (L-45c) Br
H CH (CHThree) CH2S (O) CHThree            CFThree             (L-45c) CFThree
H CH (CHThree) CH2S (O) CHThree            CFThree              L-45e
H CH (CHThree) CH2S (O) CHThree            CFThree              L-45f
H CH (CHThree) CH2S (O) CHThree            CFThree             (L-46c) F
H CH (CHThree) CH2S (O) CHThree            CFThree             (L-46c) Cl
H CH (CHThree) CH2S (O) CHThree            CFThree             (L-46c) Br
H CH (CHThree) CH2S (O) CHThree            CFThree             (L-46c) CFThree
H CH (CHThree) CH2S (O) CHThree            CFThree              L-46d
H CH (CHThree) CH2S (O) CHThree            CFThree              L-47a
H CH (CHThree) CH2S (O) CHThree            CFThree              L-47d
H CH (CHThree) CH2S (O) CHThree            CFThree             (L-48b) Br
H CH (CHThree) CH2S (O) CHThree            CFThree             (L-50b) Cl
H CH (CHThree) CH2S (O) CHThree            CFThree             (L-50b) Br
H CH (CHThree) CH2S (O) CHThree            CFThree             (L-51b) Cl
H CH (CHThree) CH2SO2CHThree             CHThree              CF2O (Ph-4-Cl)
H CH (CHThree) CH2SO2CHThree             CHThree              CH = CH (Ph-4-Cl)
H CH (CHThree) CH2SO2CHThree             CHThree              CH = CH (Ph-4-OCFThree)
H CH (CHThree) CH2SO2CHThree             CHThree              CH = CH (Ph-3,4-Cl2)
H CH (CHThree) CH2SO2CHThree             CHThree              Ph-4-F
H CH (CHThree) CH2SO2CHThree             CHThree              Ph-4-Cl
H CH (CHThree) CH2SO2CHThree             CHThree              Ph-4-Br
H CH (CHThree) CH2SO2CHThree             CHThree              Ph-4-I
H CH (CHThree) CH2SO2CHThree             CHThree              Ph-4-CFThree
H CH (CHThree) CH2SO2CHThree             CHThree              Ph-4-OCHF2
H CH (CHThree) CH2SO2CHThree             CHThree              Ph-4-OCFThree
H CH (CHThree) CH2SO2CHThree             CHThree              Ph-4-OCF2Br
H CH (CHThree) CH2SO2CHThree             CHThree              Ph-4-OCF2CHF2
H CH (CHThree) CH2SO2CHThree             CHThree              Ph-4-OCF2CHFCl
H CH (CHThree) CH2SO2CHThree             CHThree              Ph-4-OCF2CHFCFThree
H CH (CHThree) CH2SO2CHThree             CHThree              Ph-4-OCF2CHFOCFThree
H CH (CHThree) CH2SO2CHThree             CHThree              Ph-4-OCF2CHFOCF2CF2CFThree
H CH (CHThree) CH2SO2CHThree             CHThree              Ph-4-O (L-45g)
H CH (CHThree) CH2SO2CHThree             CHThree              Ph-3,4-Cl2
H CH (CHThree) CH2SO2CHThree             CHThree              Ph (-3-OCF2O-4-)
H CH (CHThree) CH2SO2CHThree             CHThree              Ph (-3-OCF2CF2O-4-)
H CH (CHThree) CH2SO2CHThree             CHThree             (L-45c) Cl
H CH (CHThree) CH2SO2CHThree             CHThree             (L-45c) Br
H CH (CHThree) CH2SO2CHThree             CHThree             (L-45c) CFThree
H CH (CHThree) CH2SO2CHThree             CHThree              L-45e
H CH (CHThree) CH2SO2CHThree             CHThree              L-45f
H CH (CHThree) CH2SO2CHThree             CHThree             (L-46c) Cl
H CH (CHThree) CH2SO2CHThree             CHThree             (L-46c) Br
H CH (CHThree) CH2SO2CHThree             CHThree             (L-46c) CFThree
H CH (CHThree) CH2SO2CHThree             CHThree              L-46d
H CH (CHThree) CH2SO2CHThree             Et Ph-4-Cl
H CH (CHThree) CH2SO2CHThree             Et Ph-4-Br
H CH (CHThree) CH2SO2CHThree             Et Ph-4-CFThree
H CH (CHThree) CH2SO2CHThree             Et Ph-4-OCFThree
H CH (CHThree) CH2SO2CHThree             Et Ph-4-OCF2Br
H CH (CHThree) CH2SO2CHThree             Et Ph-4-OCF2CHFCFThree
H CH (CHThree) CH2SO2CHThree             Et Ph-4-OCF2CHFOCFThree
H CH (CHThree) CH2SO2CHThree             Et Ph-4-OCF2CHFOCF2CF2CFThree
H CH (CHThree) CH2SO2CHThree             Et Ph-4-O (L-45g)
H CH (CHThree) CH2SO2CHThree             Et Ph-3,4-Cl2
H CH (CHThree) CH2SO2CHThree             Et Ph (-3-OCF2O-4-)
H CH (CHThree) CH2SO2CHThree             Et Ph (-3-OCF2CF2O-4-)
H CH (CHThree) CH2SO2CHThree             Et (L-45c) CFThree
H CH (CHThree) CH2SO2CHThree             n-Pr Ph-4-Br
H CH (CHThree) CH2SO2CHThree             n-Pr Ph-4-CFThree
H CH (CHThree) CH2SO2CHThree             n-Pr Ph-4-OCFThree
H CH (CHThree) CH2SO2CHThree             n-Pr (L-45c) CFThree
H CH (CHThree) CH2SO2CHThree             i-Pr Ph-4-Br
H CH (CHThree) CH2SO2CHThree             i-Pr Ph-4-CFThree
H CH (CHThree) CH2SO2CHThree             i-Pr Ph-4-OCFThree
H CH (CHThree) CH2SO2CHThree             i-Pr (L-45c) CFThree
H CH (CHThree) CH2SO2CHThree             c-Pr Ph-4-Br
H CH (CHThree) CH2SO2CHThree             c-Pr Ph-4-CFThree
H CH (CHThree) CH2SO2CHThree             c-Pr Ph-4-OCFThree
H CH (CHThree) CH2SO2CHThree             c-Pr (L-45c) CFThree
H CH (CHThree) CH2SO2CHThree             n-Bu (L-45c) CFThree
H CH (CHThree) CH2SO2CHThree             CH2F Ph-4-Br
H CH (CHThree) CH2SO2CHThree             CH2Cl Ph-4-CFThree
H CH (CHThree) CH2SO2CHThree             CH2Br Ph-4-OCFThree
H CH (CHThree) CH2SO2CHThree             CHF2             Ph-4-Cl
H CH (CHThree) CH2SO2CHThree             CHF2             Ph-4-Br
H CH (CHThree) CH2SO2CHThree             CHF2             Ph-4-CFThree
H CH (CHThree) CH2SO2CHThree             CHF2             Ph-4-OCFThree
H CH (CHThree) CH2SO2CHThree             CHF2             Ph-4-OCF2Br
H CH (CHThree) CH2SO2CHThree             CHF2             Ph-4-OCF2CHFCFThree
H CH (CHThree) CH2SO2CHThree             CHF2             Ph-4-OCF2CHFOCFThree
H CH (CHThree) CH2SO2CHThree             CHF2             Ph-4-OCF2CHFOCF2CF2CFThree
H CH (CHThree) CH2SO2CHThree             CHF2             Ph-4-O (L-45g)
H CH (CHThree) CH2SO2CHThree             CHF2             Ph-3,4-Cl2
H CH (CHThree) CH2SO2CHThree             CHF2             Ph (-3-OCF2O-4-)
H CH (CHThree) CH2SO2CHThree             CHF2             Ph (-3-OCF2CF2O-4-)
H CH (CHThree) CH2SO2CHThree             CHF2            (L-45c) CFThree
H CH (CHThree) CH2SO2CHThree             CHF2             L-45f
H CH (CHThree) CH2SO2CHThree             CHF2            (L-46c) CFThree
H CH (CHThree) CH2SO2CHThree             CHF2             L-46d
H CH (CHThree) CH2SO2CHThree             CHFCl (L-45c) CFThree
H CH (CHThree) CH2SO2CHThree             CHFBr Ph-4-Br
H CH (CHThree) CH2SO2CHThree             CFThree              c-Pr
H CH (CHThree) CH2SO2CHThree             CFThree              c-Bu
H CH (CHThree) CH2SO2CHThree             CFThree              c-Pen
H CH (CHThree) CH2SO2CHThree             CFThree              c-Hex
H CH (CHThree) CH2SO2CHThree             CFThree              T-1
H CH (CHThree) CH2SO2CHThree             CFThree              T-2
H CH (CHThree) CH2SO2CHThree             CFThree              T-3
H CH (CHThree) CH2SO2CHThree             CFThree              T-4
H CH (CHThree) CH2SO2CHThree             CFThree              T-5
H CH (CHThree) CH2SO2CHThree             CFThree              CH2OCHThree
H CH (CHThree) CH2SO2CHThree             CFThree              CH2OEt
H CH (CHThree) CH2SO2CHThree             CFThree              CH2OPr-n
H CH (CHThree) CH2SO2CHThree             CFThree              CH2OPr-i
H CH (CHThree) CH2SO2CHThree             CFThree              CH2OBu-n
H CH (CHThree) CH2SO2CHThree             CFThree              CH2OC (O) (Ph-2-Cl)
H CH (CHThree) CH2SO2CHThree             CFThree              CH2OC (O) (Ph-3-Cl)
H CH (CHThree) CH2SO2CHThree             CFThree              CH2OC (O) (Ph-4-Cl)
H CH (CHThree) CH2SO2CHThree             CFThree              CH2OPh
H CH (CHThree) CH2SO2CHThree             CFThree              CH2O (Ph-2-F)
H CH (CHThree) CH2SO2CHThree             CFThree              CH2O (Ph-3-F)
H CH (CHThree) CH2SO2CHThree             CFThree              CH2O (Ph-4-F)
H CH (CHThree) CH2SO2CHThree             CFThree              CH2O (Ph-2-Cl)
H CH (CHThree) CH2SO2CHThree             CFThree              CH2O (Ph-3-Cl)
H CH (CHThree) CH2SO2CHThree             CFThree              CH2O (Ph-4-Cl)
H CH (CHThree) CH2SO2CHThree             CFThree              CH2O (Ph-2-Br)
H CH (CHThree) CH2SO2CHThree             CFThree              CH2O (Ph-3-Br)
H CH (CHThree) CH2SO2CHThree             CFThree              CH2O (Ph-4-Br)
H CH (CHThree) CH2SO2CHThree             CFThree              CH2O (Ph-2-CFThree)
H CH (CHThree) CH2SO2CHThree             CFThree              CH2O (Ph-3-CFThree)
H CH (CHThree) CH2SO2CHThree             CFThree              CH2O (Ph-4-CFThree)
H CH (CHThree) CH2SO2CHThree             CFThree              CH2O (Ph-2-OCFThree)
H CH (CHThree) CH2SO2CHThree             CFThree              CH2O (Ph-3-OCFThree)
H CH (CHThree) CH2SO2CHThree             CFThree              CH2O (Ph-4-OCFThree)
H CH (CHThree) CH2SO2CHThree             CFThree              CF2OPh
H CH (CHThree) CH2SO2CHThree             CFThree              CF2O (Ph-2-F)
H CH (CHThree) CH2SO2CHThree             CFThree              CF2O (Ph-3-F)
H CH (CHThree) CH2SO2CHThree             CFThree              CF2O (Ph-4-F)
H CH (CHThree) CH2SO2CHThree             CFThree              CF2O (Ph-2-Cl)
H CH (CHThree) CH2SO2CHThree             CFThree              CF2O (Ph-3-Cl)
H CH (CHThree) CH2SO2CHThree             CFThree              CF2O (Ph-4-Cl)
H CH (CHThree) CH2SO2CHThree             CFThree              CF2O (Ph-2-Br)
H CH (CHThree) CH2SO2CHThree             CFThree              CF2O (Ph-3-Br)
H CH (CHThree) CH2SO2CHThree             CFThree              CF2O (Ph-4-Br)
H CH (CHThree) CH2SO2CHThree             CFThree              CF2O (Ph-2-CFThree)
H CH (CHThree) CH2SO2CHThree             CFThree              CF2O (Ph-3-CFThree)
H CH (CHThree) CH2SO2CHThree             CFThree              CF2O (Ph-4-CFThree)
H CH (CHThree) CH2SO2CHThree             CFThree              CF2O (Ph-2-OCFThree)
H CH (CHThree) CH2SO2CHThree             CFThree              CF2O (Ph-3-OCFThree)
H CH (CHThree) CH2SO2CHThree             CFThree              CF2O (Ph-4-OCFThree)
H CH (CHThree) CH2SO2CHThree             CFThree              CH2S (Ph-2-Cl)
H CH (CHThree) CH2SO2CHThree             CFThree              CH2S (Ph-3-Cl)
H CH (CHThree) CH2SO2CHThree             CFThree              CH2S (Ph-4-Cl)
H CH (CHThree) CH2SO2CHThree             CFThree              CH2SO2(Ph-2-Cl)
H CH (CHThree) CH2SO2CHThree             CFThree              CH2SO2(Ph-3-Cl)
H CH (CHThree) CH2SO2CHThree             CFThree              CH2SO2(Ph-4-Cl)
H CH (CHThree) CH2SO2CHThree             CFThree              CH2N (CHThree)2
H CH (CHThree) CH2SO2CHThree             CFThree              CH2NH (Ph-2-Cl)
H CH (CHThree) CH2SO2CHThree             CFThree              CH2NH (Ph-3-Cl)
H CH (CHThree) CH2SO2CHThree             CFThree              CH2NH (Ph-4-Cl)
H CH (CHThree) CH2SO2CHThree             CFThree              CF2C (O) OEt
H CH (CHThree) CH2SO2CHThree             CFThree              CH2(L-5a)
H CH (CHThree) CH2SO2CHThree             CFThree              CH2(L-14a)
H CH (CHThree) CH2SO2CHThree             CFThree              CH2(L-24a)
H CH (CHThree) CH2SO2CHThree             CFThree              CH2(L-36a)
H CH (CHThree) CH2SO2CHThree             CFThree              CH2CH2Ph
H CH (CHThree) CH2SO2CHThree             CFThree              CH2CH2(Ph-2-Cl)
H CH (CHThree) CH2SO2CHThree             CFThree              CH2CH2(Ph-3-Cl)
H CH (CHThree) CH2SO2CHThree             CFThree              CH2CH2(Ph-4-Cl)
H CH (CHThree) CH2SO2CHThree             CFThree              T-22
H CH (CHThree) CH2SO2CHThree             CFThree              T-23
H CH (CHThree) CH2SO2CHThree             CFThree              T-24
H CH (CHThree) CH2SO2CHThree             CFThree              C (O) OEt
H CH (CHThree) CH2SO2CHThree             CFThree              C (O) OBu-t
H CH (CHThree) CH2SO2CHThree             CFThree              C (O) OCH2CFThree
H CH (CHThree) CH2SO2CHThree             CFThree              CH = CH (Ph-2-F)
H CH (CHThree) CH2SO2CHThree             CFThree              CH = CH (Ph-3-F)
H CH (CHThree) CH2SO2CHThree             CFThree              CH = CH (Ph-4-F)
H CH (CHThree) CH2SO2CHThree             CFThree              CH = CH (Ph-2-Cl)
H CH (CHThree) CH2SO2CHThree             CFThree              CH = CH (Ph-3-Cl)
H CH (CHThree) CH2SO2CHThree             CFThree              CH = CH (Ph-4-Cl)
H CH (CHThree) CH2SO2CHThree             CFThree              CH = CH (Ph-2-Br)
H CH (CHThree) CH2SO2CHThree             CFThree              CH = CH (Ph-3-Br)
H CH (CHThree) CH2SO2CHThree             CFThree              CH = CH (Ph-4-Br)
H CH (CHThree) CH2SO2CHThree             CFThree              CH = CH (Ph-2-CFThree)
H CH (CHThree) CH2SO2CHThree             CFThree              CH = CH (Ph-3-CFThree)
H CH (CHThree) CH2SO2CHThree             CFThree              CH = CH (Ph-4-CFThree)
H CH (CHThree) CH2SO2CHThree             CFThree              CH = CH (Ph-2-OCFThree)
H CH (CHThree) CH2SO2CHThree             CFThree              CH = CH (Ph-3-OCFThree)
H CH (CHThree) CH2SO2CHThree             CFThree              CH = CH (Ph-4-OCFThree)
H CH (CHThree) CH2SO2CHThree             CFThree              CH = CH (Ph-2-SCHThree)
H CH (CHThree) CH2SO2CHThree             CFThree              CH = CH (Ph-3-SCHThree)
H CH (CHThree) CH2SO2CHThree             CFThree              CH = CH (Ph-4-SCHThree)
H CH (CHThree) CH2SO2CHThree             CFThree              CH = CH (Ph-2-SO2CHThree)
H CH (CHThree) CH2SO2CHThree             CFThree              CH = CH (Ph-3-SO2CHThree)
H CH (CHThree) CH2SO2CHThree             CFThree              CH = CH (Ph-4-SO2CHThree)
H CH (CHThree) CH2SO2CHThree             CFThree              CH = CH (Ph-3,4-F2)
H CH (CHThree) CH2SO2CHThree             CFThree              CH = CH (Ph-3-F-4-Cl)
H CH (CHThree) CH2SO2CHThree             CFThree              CH = CH (Ph-3,4-Cl2)
H CH (CHThree) CH2SO2CHThree             CFThree              CH = CH (Ph-3,4-Br2)
H CH (CHThree) CH2SO2CHThree             CFThree              CH = CH (Ph-3-F-4-CFThree)
H CH (CHThree) CH2SO2CHThree             CFThree              CH = CH (Ph-3-Cl-4-OCFThree)
H CH (CHThree) CH2SO2CHThree             CFThree              CH = CH [Ph (-3-OCF2O-4-)]
H CH (CHThree) CH2SO2CHThree             CFThree              Ph
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-2-F
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-3-F
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-4-F
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-2-Cl
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-3-Cl
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-4-Cl
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-2-Br
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-3-Br
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-4-Br
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-4-I
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-4-Bu-t
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-2-CFThree
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-3-CFThree
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-4-CFThree
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-4-OCHThree
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-4-OCHF2
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-2-OCFThree
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-3-OCFThree
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-4-OCFThree
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-4-OCF2Br
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-4-OCH2CFThree
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-4-OCF2CHF2
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-4-OCF2CHFCl
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-4-OCF2CHFBr
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-4-OCF2CF2Br
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-4-OCF2CFCl2
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-4-OCF2CClThree
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-4-OCH2CF2CHF2
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-3-OCF2CHFCFThree
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-4-OCF2CHFCFThree
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-4-OCH (CFThree)2
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-4-OCF2CFBrCFThree
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-3-OCF2CHFOCFThree
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-4-OCF2CHFOCFThree
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-4-OCF2CHFOCF2CF2CFThree
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-4-OSO2CHThree
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-4-OSO2CFThree
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-3-O (Ph-4-Cl)
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-4-O (Ph-4-Cl)
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-4-O (Ph-4-Br)
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-4-O (Ph-4-CFThree)
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-4-O (L-45c) Br
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-4-O (L-45c) CFThree
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-3-O (L-45e)
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-4-O (L-45e)
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-4-O (L-48b) Br
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-4-SCHThree
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-4-SO2CHThree
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-3-S (Ph-4-Cl)
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-4-S (Ph-4-Cl)
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-4-S (Ph-4-Br)
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-4-S (Ph-4-CFThree)
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-4-S (L-45c) Br
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-4-S (L-45c) CFThree
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-4-S (L-45e)
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-4-S (L-48b) Br
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-4-NO2
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-4-CN
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-2,3-F2
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-2,4-F2
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-3,4-F2
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-2,5-F2
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-3,5-F2
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-2-Cl-4-F
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-2-F-3-Cl
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-3-Cl-4-F
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-2-F-4-Cl
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-3-F-4-Cl
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-2,3-Cl2
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-2,4-Cl2
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-2,5-Cl2
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-3,4-Cl2
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-3,5-Cl2
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-3-Br-4-F
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-2-F-4-Br
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-2-F-5-Br
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-3,4-Br2
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-3,5-Br2
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-3-CHThree-4-F
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-3-F-4-CHThree
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-2-F-5-CHThree
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-2,4- (CHThree)2
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-3,4- (CHThree)2
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-2-F-3-CFThree
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-3-CFThree-4-F
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-3-CFThree-4-Cl
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-2-F-4-CFThree
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-3-F-4-CFThree
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-2-F-5-CFThree
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-3-F-5-CFThree
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-2-Cl-4-CFThree
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-3,5- (CFThree)2
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-3-Br-4-OCHThree
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-3-F-4-OCHF2
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-3-Cl-4-OCHF2
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-3-Br-4-OCHF2
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-3-F-4-OCFThree
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-3-Cl-4-OCFThree
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-3-Br-4-OCFThree
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-3-F-4-OCF2Br
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-3-Cl-4-OCF2Br
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-3-Br-4-OCF2Br
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-3-F-4-OCF2CHF2
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-3-Cl-4-OCF2CHF2
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-3-Br-4-OCF2CHF2
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-3-F-4-OCF2CHFCl
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-3-Cl-4-OCF2CHFCl
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-3-Br-4-OCF2CHFCl
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-3-F-4-OCF2CHFCFThree
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-3-Cl-4-OCF2CHFCFThree
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-3-Br-4-OCF2CHFCFThree
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-3-F-4-OCF2CHFOCFThree
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-3-Cl-4-OCF2CHFOCFThree
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-3-Br-4-OCF2CHFOCFThree
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-3-CHThree-4-OCF2CHFOCFThree
H CH (CHThree) CH2SO2CHThree             CFThree         Ph-3-F-4-OCF2CHFOCF2CF2CFThree
H CH (CHThree) CH2SO2CHThree             CFThree         Ph-3-Cl-4-OCF2CHFOCF2CF2CFThree
H CH (CHThree) CH2SO2CHThree             CFThree         Ph-3-Br-4-OCF2CHFOCF2CF2CFThree
H CH (CHThree) CH2SO2CHThree             CFThree              Ph (-3-OCF2O-4-)
H CH (CHThree) CH2SO2CHThree             CFThree              Ph (-3-OCF2CF2O-4-)
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-3-OPh-4-F
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-3-NO2-4-F
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-3-NO2-4-Cl
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-2-F-5-NO2
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-3-CN-4-F
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-2,3,4-FThree
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-2,3,5-FThree
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-2,4,5-FThree
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-3,4,5-FThree
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-2,3-F2-4-CHThree
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-2,3-F2-4-CFThree
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-3,4-F2-5-CFThree
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-2-F-3-Cl-5-CFThree
H CH (CHThree) CH2SO2CHThree             CFThree              Ph-3,5-Cl2-4-OCHThree
H CH (CHThree) CH2SO2CHThree             CFThree              1-Naph
H CH (CHThree) CH2SO2CHThree             CFThree              2-Naph
H CH (CHThree) CH2SO2CHThree             CFThree             (L-1b) Br
H CH (CHThree) CH2SO2CHThree             CFThree             (L-1c) Cl
H CH (CHThree) CH2SO2CHThree             CFThree             (L-1c) Br
H CH (CHThree) CH2SO2CHThree             CFThree             (L-1c) I
H CH (CHThree) CH2SO2CHThree             CFThree             (L-1c) CFThree
H CH (CHThree) CH2SO2CHThree             CFThree             (L-2b) Br
H CH (CHThree) CH2SO2CHThree             CFThree             (L-3b) Cl
H CH (CHThree) CH2SO2CHThree             CFThree             (L-3b) Br
H CH (CHThree) CH2SO2CHThree             CFThree             (L-3c) F
H CH (CHThree) CH2SO2CHThree             CFThree             (L-3c) Cl
H CH (CHThree) CH2SO2CHThree             CFThree             (L-3c) Br
H CH (CHThree) CH2SO2CHThree             CFThree             (L-3c) I
H CH (CHThree) CH2SO2CHThree             CFThree             (L-3c) CFThree
H CH (CHThree) CH2SO2CHThree             CFThree             (L-3c) CN
H CH (CHThree) CH2SO2CHThree             CFThree              L-3d
H CH (CHThree) CH2SO2CHThree             CFThree             (L-4b) Cl
H CH (CHThree) CH2SO2CHThree             CFThree             (L-4b) Br
H CH (CHThree) CH2SO2CHThree             CFThree             (L-4b) CN
H CH (CHThree) CH2SO2CHThree             CFThree             (L-10b) Cl
H CH (CHThree) CH2SO2CHThree             CFThree             (L-10b) Br
H CH (CHThree) CH2SO2CHThree             CFThree             (L-15b) CFThree
H CH (CHThree) CH2SO2CHThree             CFThree             (L-16a) CHF2
H CH (CHThree) CH2SO2CHThree             CFThree             (L-16a) CF2Br
H CH (CHThree) CH2SO2CHThree             CFThree             (L-17a) Cl
H CH (CHThree) CH2SO2CHThree             CFThree             (L-21b) Cl
H CH (CHThree) CH2SO2CHThree             CFThree             (L-21b) Br
H CH (CHThree) CH2SO2CHThree             CFThree             (L-21b) I
H CH (CHThree) CH2SO2CHThree             CFThree             (L-21b) CFThree
H CH (CHThree) CH2SO2CHThree             CFThree             (L-22b) Cl
H CH (CHThree) CH2SO2CHThree             CFThree             (L-22b) Br
H CH (CHThree) CH2SO2CHThree             CFThree             (L-23b) Cl
H CH (CHThree) CH2SO2CHThree             CFThree             (L-23b) Br
H CH (CHThree) CH2SO2CHThree             CFThree             (L-23c) Cl
H CH (CHThree) CH2SO2CHThree             CFThree             (L-23c) Br
H CH (CHThree) CH2SO2CHThree             CFThree             (L-31a) Cl
H CH (CHThree) CH2SO2CHThree             CFThree             (L-31a) Br
H CH (CHThree) CH2SO2CHThree             CFThree             (L-45c) F
H CH (CHThree) CH2SO2CHThree             CFThree             (L-45c) Cl
H CH (CHThree) CH2SO2CHThree             CFThree             (L-45c) Br
H CH (CHThree) CH2SO2CHThree             CFThree             (L-45c) I
H CH (CHThree) CH2SO2CHThree             CFThree             (L-45c) CFThree
H CH (CHThree) CH2SO2CHThree             CFThree              L-45e
H CH (CHThree) CH2SO2CHThree             CFThree              L-45f
H CH (CHThree) CH2SO2CHThree             CFThree             (L-46c) F
H CH (CHThree) CH2SO2CHThree             CFThree             (L-46c) Cl
H CH (CHThree) CH2SO2CHThree             CFThree             (L-46c) Br
H CH (CHThree) CH2SO2CHThree             CFThree             (L-46c) I
H CH (CHThree) CH2SO2CHThree             CFThree             (L-46c) CFThree
H CH (CHThree) CH2SO2CHThree             CFThree             (L-46c) OCH2CFThree
H CH (CHThree) CH2SO2CHThree             CFThree             (L-46c) OCH (CFThree)2
H CH (CHThree) CH2SO2CHThree             CFThree              L-46d
H CH (CHThree) CH2SO2CHThree             CFThree              L-47a
H CH (CHThree) CH2SO2CHThree             CFThree              L-47d
H CH (CHThree) CH2SO2CHThree             CFThree             (L-48b) Br
H CH (CHThree) CH2SO2CHThree             CFThree             (L-50b) Cl
H CH (CHThree) CH2SO2CHThree             CFThree             (L-50b) Br
H CH (CHThree) CH2SO2CHThree             CFThree             (L-51b) Cl
H CH (CHThree) CH2SO2CHThree             CF2Cl Ph-4-Cl
H CH (CHThree) CH2SO2CHThree             CF2Cl Ph-4-Br
H CH (CHThree) CH2SO2CHThree             CF2Cl Ph-4-CFThree
H CH (CHThree) CH2SO2CHThree             CF2Cl Ph-4-OCFThree
H CH (CHThree) CH2SO2CHThree             CF2Cl Ph-4-OCF2Br
H CH (CHThree) CH2SO2CHThree             CF2Cl Ph-4-OCF2CHFCFThree
H CH (CHThree) CH2SO2CHThree             CF2Cl Ph-4-OCF2CHFOCFThree
H CH (CHThree) CH2SO2CHThree             CF2Cl Ph-4-OCF2CHFOCF2CF2CFThree
H CH (CHThree) CH2SO2CHThree             CF2Cl Ph-4-O (L-45g)
H CH (CHThree) CH2SO2CHThree             CF2Cl Ph-3,4-Cl2
H CH (CHThree) CH2SO2CHThree             CF2Cl Ph (-3-OCF2O-4-)
H CH (CHThree) CH2SO2CHThree             CF2Cl Ph (-3-OCF2CF2O-4-)
H CH (CHThree) CH2SO2CHThree             CF2Cl (L-45c) CFThree
H CH (CHThree) CH2SO2CHThree             CF2Cl L-45f
H CH (CHThree) CH2SO2CHThree             CF2Cl (L-46c) CFThree
H CH (CHThree) CH2SO2CHThree             CF2Cl L-46d
H CH (CHThree) CH2SO2CHThree             CFCl2            Ph-4-CFThree
H CH (CHThree) CH2SO2CHThree             CF2Br Ph-4-Cl
H CH (CHThree) CH2SO2CHThree             CF2Br Ph-4-Br
H CH (CHThree) CH2SO2CHThree             CF2Br Ph-4-CFThree
H CH (CHThree) CH2SO2CHThree             CF2Br Ph-4-OCFThree
H CH (CHThree) CH2SO2CHThree             CF2Br Ph-4-OCF2Br
H CH (CHThree) CH2SO2CHThree             CF2Br Ph-4-OCF2CHFCFThree
H CH (CHThree) CH2SO2CHThree             CF2Br Ph-4-OCF2CHFOCFThree
H CH (CHThree) CH2SO2CHThree             CF2Br Ph-4-OCF2CHFOCF2CF2CFThree
H CH (CHThree) CH2SO2CHThree             CF2Br Ph-4-O (L-45g)
H CH (CHThree) CH2SO2CHThree             CF2Br Ph-3,4-Cl2
H CH (CHThree) CH2SO2CHThree             CF2Br Ph (-3-OCF2O-4-)
H CH (CHThree) CH2SO2CHThree             CF2Br Ph (-3-OCF2CF2O-4-)
H CH (CHThree) CH2SO2CHThree             CF2Br (L-45c) CFThree
H CH (CHThree) CH2SO2CHThree             CF2Br L-45f
H CH (CHThree) CH2SO2CHThree             CF2Br (L-46c) CFThree
H CH (CHThree) CH2SO2CHThree             CF2Br L-46d
H CH (CHThree) CH2SO2CHThree             CFClBr Ph-4-OCFThree
H CH (CHThree) CH2SO2CHThree             CFBr2           (L-45c) CFThree
H CH (CHThree) CH2SO2CHThree             CF2CHF2          Ph-4-Br
H CH (CHThree) CH2SO2CHThree             CF2CFThree           Ph-4-Cl
H CH (CHThree) CH2SO2CHThree             CF2CFThree           Ph-4-Br
H CH (CHThree) CH2SO2CHThree             CF2CFThree           Ph-4-CFThree
H CH (CHThree) CH2SO2CHThree             CF2CFThree           Ph-4-OCFThree
H CH (CHThree) CH2SO2CHThree             CF2CFThree           Ph-4-OCF2Br
H CH (CHThree) CH2SO2CHThree             CF2CFThree           Ph-4-OCF2CHFCFThree
H CH (CHThree) CH2SO2CHThree             CF2CFThree           Ph-4-OCF2CHFOCFThree
H CH (CHThree) CH2SO2CHThree             CF2CFThree           Ph-4-OCF2CHFOCF2CF2CFThree
H CH (CHThree) CH2SO2CHThree             CF2CFThree           Ph-4-O (L-45g)
H CH (CHThree) CH2SO2CHThree             CF2CFThree           Ph-3,4-Cl2
H CH (CHThree) CH2SO2CHThree             CF2CFThree           Ph (-3-OCF2O-4-)
H CH (CHThree) CH2SO2CHThree             CF2CFThree           Ph (-3-OCF2CF2O-4-)
H CH (CHThree) CH2SO2CHThree             CF2CFThree          (L-45c) CFThree
H CH (CHThree) CH2SO2CHThree             CF2CFThree           L-45f
H CH (CHThree) CH2SO2CHThree             CF2CFThree          (L-46c) CFThree
H CH (CHThree) CH2SO2CHThree             CF2CFThree           L-46d
H CH (CHThree) CH2SO2CHThree             CF2CF2Cl Ph-4-CFThree
H CH (CHThree) CH2SO2CHThree             CFClCFThree          Ph-4-OCFThree
H CH (CHThree) CH2SO2CHThree             CFClCF2Cl (L-45c) CFThree
H CH (CHThree) CH2SO2CHThree             CF2CF2Br Ph-4-Br
H CH (CHThree) CH2SO2CHThree             CFBrCFThree          Ph-4-CFThree
H CH (CHThree) CH2SO2CHThree             CF2CHFCFThree        Ph-4-OCFThree
H CH (CHThree) CH2SO2CHThree             CF2CF2CFThree        Ph-4-Cl
H CH (CHThree) CH2SO2CHThree             CF2CF2CFThree        Ph-4-Br
H CH (CHThree) CH2SO2CHThree             CF2CF2CFThree        Ph-4-CFThree
H CH (CHThree) CH2SO2CHThree             CF2CF2CFThree        Ph-4-OCFThree
H CH (CHThree) CH2SO2CHThree             CF2CF2CFThree        Ph-4-OCF2Br
H CH (CHThree) CH2SO2CHThree             CF2CF2CFThree        Ph-4-OCF2CHFCFThree
H CH (CHThree) CH2SO2CHThree             CF2CF2CFThree        Ph-4-OCF2CHFOCFThree
H CH (CHThree) CH2SO2CHThree             CF2CF2CFThree        Ph-4-OCF2CHFOCF2CF2CFThree
H CH (CHThree) CH2SO2CHThree             CF2CF2CFThree        Ph-4-O (L-45g)
H CH (CHThree) CH2SO2CHThree             CF2CF2CFThree        Ph-3,4-Cl2
H CH (CHThree) CH2SO2CHThree             CF2CF2CFThree        Ph (-3-OCF2O-4-)
H CH (CHThree) CH2SO2CHThree             CF2CF2CFThree        Ph (-3-OCF2CF2O-4-)
H CH (CHThree) CH2SO2CHThree             CF2CF2CFThree       (L-45c) CFThree
H CH (CHThree) CH2SO2CHThree             CF2CF2CFThree        L-45f
H CH (CHThree) CH2SO2CHThree             CF2CF2CFThree       (L-46c) CFThree
H CH (CHThree) CH2SO2CHThree             CF2CF2CFThree        L-46d
H CH (CHThree) CH2SO2CHThree             CF (CFThree)2        (L-45c) CFThree
H CH (CHThree) CH2SO2CHThree             CF2CF2CF2CFThree     Ph-4-Br
H CH (CHThree) CH2SO2CHThree             T-1 Ph-4-CFThree
H CH (CHThree) CH2SO2CHThree             T-2 Ph-4-OCFThree
H CH (CHThree) CH2SO2CHThree             CH2OCHThree         (L-45c) CFThree
H CH (CHThree) CH2SO2CHThree             CH2OEt Ph-4-Br
H CH (CHThree) CH2SO2CHThree             CH2OCH2CFThree       Ph-4-CFThree 
H CH (CHThree) CH2SO2CHThree             CH2OCH (CFThree)2     Ph-4-OCFThree
H CH (CHThree) CH2SO2CHThree             CF2OCHThree          Ph-4-Cl
H CH (CHThree) CH2SO2CHThree             CF2OCHThree          Ph-4-Br
H CH (CHThree) CH2SO2CHThree             CF2OCHThree          Ph-4-CFThree
H CH (CHThree) CH2SO2CHThree             CF2OCHThree          Ph-4-OCFThree
H CH (CHThree) CH2SO2CHThree             CF2OCHThree          Ph-4-OCF2Br
H CH (CHThree) CH2SO2CHThree             CF2OCHThree          Ph-4-OCF2CHFCFThree
H CH (CHThree) CH2SO2CHThree             CF2OCHThree          Ph-4-OCF2CHFOCFThree
H CH (CHThree) CH2SO2CHThree             CF2OCHThree          Ph-4-OCF2CHFOCF2CF2CFThree
H CH (CHThree) CH2SO2CHThree             CF2OCHThree          Ph-4-O (L-45g)
H CH (CHThree) CH2SO2CHThree             CF2OCHThree          Ph-3,4-Cl2
H CH (CHThree) CH2SO2CHThree             CF2OCHThree          Ph (-3-OCF2O-4-)
H CH (CHThree) CH2SO2CHThree             CF2OCHThree          Ph (-3-OCF2CF2O-4-)
H CH (CHThree) CH2SO2CHThree             CF2OCHThree         (L-45c) CFThree
H CH (CHThree) CH2SO2CHThree             CF2OCHThree          L-45f
H CH (CHThree) CH2SO2CHThree             CF2OCHThree         (L-46c) CFThree
H CH (CHThree) CH2SO2CHThree             CF2OCHThree          L-46d
H CH (CHThree) CH2SO2CHThree             CH2SCHThree         (L-45c) CFThree
H CH (CHThree) CH2SO2CHThree             CH2SO2CHThree        Ph-4-Br
H CH (CHThree) CH2SO2CHThree             CH2SCFThree          Ph-4-CFThree
H CH (CHThree) CH2SO2CHThree             CF2SCHThree          Ph-4-Cl
H CH (CHThree) CH2SO2CHThree             CF2SCHThree          Ph-4-Br
H CH (CHThree) CH2SO2CHThree             CF2SCHThree          Ph-4-CFThree
H CH (CHThree) CH2SO2CHThree             CF2SCHThree          Ph-4-OCFThree
H CH (CHThree) CH2SO2CHThree             CF2SCHThree          Ph-4-OCF2Br
H CH (CHThree) CH2SO2CHThree             CF2SCHThree          Ph-4-OCF2CHFCFThree
H CH (CHThree) CH2SO2CHThree             CF2SCHThree          Ph-4-OCF2CHFOCFThree
H CH (CHThree) CH2SO2CHThree             CF2SCHThree          Ph-4-OCF2CHFOCF2CF2CFThree
H CH (CHThree) CH2SO2CHThree             CF2SCHThree          Ph-4-O (L-45g)
H CH (CHThree) CH2SO2CHThree             CF2SCHThree          Ph-3,4-Cl2
H CH (CHThree) CH2SO2CHThree             CF2SCHThree          Ph (-3-OCF2O-4-)
H CH (CHThree) CH2SO2CHThree             CF2SCHThree          Ph (-3-OCF2CF2O-4-)
H CH (CHThree) CH2SO2CHThree             CF2SCHThree         (L-45c) CFThree
H CH (CHThree) CH2SO2CHThree             CF2SCHThree          L-45f
H CH (CHThree) CH2SO2CHThree             CF2SCHThree         (L-46c) CFThree
H CH (CHThree) CH2SO2CHThree             CF2SCHThree          L-46d
H CH (CHThree) CH2SO2CHThree             CF2SEt Ph-4-OCFThree
H CH (CHThree) CH2SO2CHThree             CF2SPr-n (L-45c) CFThree
H CH (CHThree) CH2SO2CHThree             CF2SPr-i Ph-4-Br
H CH (CHThree) CH2SO2CHThree             CF2SCH2Ph Ph-4-CFThree
H CH (CHThree) CH2SO2CHThree             CF2SPh Ph-4-OCFThree
H CH (CHThree) CH2SO2CHThree             CF2C (O) OEt (L-45c) CFThree
H CH (CHThree) CH2SO2CHThree             CF2SO2N (CHThree)2    Ph-4-Br
H CH (CHThree) CH2SO2CHThree             C (O) OEt Ph-4-CFThree
H CH (CHThree) CH2SO2CHThree             C (O) SEt Ph-4-OCFThree
H CH (CHThree) CH2SEt CFThree              CH = CH (Ph-4-Cl)
H CH (CHThree) CH2SEt CFThree              Ph-4-Cl
H CH (CHThree) CH2SEt CFThree              Ph-4-Br
H CH (CHThree) CH2SEt CFThree              Ph-4-CFThree
H CH (CHThree) CH2SEt CFThree              Ph-4-OCFThree
H CH (CHThree) CH2SEt (R) CFThree              Ph-4-OCFThree
H CH (CHThree) CH2SEt (S) CFThree              Ph-4-OCFThree
H CH (CHThree) CH2SEt CFThree              Ph-4-OCF2Br
H CH (CHThree) CH2SEt CFThree              Ph-4-OCF2CHFCFThree
H CH (CHThree) CH2SEt CFThree              Ph-4-OCF2CHFOCFThree
H CH (CHThree) CH2SEt CFThree              Ph-4-OCF2CHFOCF2CF2CFThree
H CH (CHThree) CH2SEt CFThree              Ph-4-O (L-45g)
H CH (CHThree) CH2SEt CFThree              Ph-3,4-Cl2
H CH (CHThree) CH2SEt CFThree              Ph (-3-OCF2O-4-)
H CH (CHThree) CH2SEt CFThree              Ph (-3-OCF2CF2O-4-)
H CH (CHThree) CH2SEt CFThree             (L-45c) CFThree
H CH (CHThree) CH2SEt CFThree              L-45f
H CH (CHThree) CH2SEt CFThree             (L-46c) CFThree
H CH (CHThree) CH2SEt CFThree              L-46d
H CH (CHThree) CH2S (O) Et CFThree              CH = CH (Ph-4-Cl)
H CH (CHThree) CH2S (O) Et CFThree              Ph-4-Cl
H CH (CHThree) CH2S (O) Et CFThree              Ph-4-Br
H CH (CHThree) CH2S (O) Et CFThree              Ph-4-CFThree
H CH (CHThree) CH2S (O) Et CFThree              Ph-4-OCFThree
H CH (CHThree) CH2S (O) Et CFThree              Ph-4-OCF2Br
H CH (CHThree) CH2S (O) Et CFThree              Ph-4-OCF2CHFCFThree
H CH (CHThree) CH2S (O) Et CFThree              Ph-4-OCF2CHFOCFThree
H CH (CHThree) CH2S (O) Et CFThree              Ph-4-OCF2CHFOCF2CF2CFThree
H CH (CHThree) CH2S (O) Et CFThree              Ph-4-O (L-45g)
H CH (CHThree) CH2S (O) Et CFThree              Ph-3,4-Cl2
H CH (CHThree) CH2S (O) Et CFThree              Ph (-3-OCF2O-4-)
H CH (CHThree) CH2S (O) Et CFThree              Ph (-3-OCF2CF2O-4-)
H CH (CHThree) CH2S (O) Et CFThree             (L-45c) CFThree
H CH (CHThree) CH2S (O) Et CFThree              L-45f
H CH (CHThree) CH2S (O) Et CFThree             (L-46c) CFThree
H CH (CHThree) CH2S (O) Et CFThree              L-46d
H CH (CHThree) CH2SO2Et CFThree              CH = CH (Ph-4-Cl)
H CH (CHThree) CH2SO2Et CFThree              Ph-4-Cl
H CH (CHThree) CH2SO2Et CFThree              Ph-4-Br
H CH (CHThree) CH2SO2Et CFThree              Ph-4-CFThree
H CH (CHThree) CH2SO2Et CFThree              Ph-4-OCFThree
H CH (CHThree) CH2SO2Et CFThree              Ph-4-OCF2Br
H CH (CHThree) CH2SO2Et CFThree              Ph-4-OCF2CHFCFThree
H CH (CHThree) CH2SO2Et CFThree              Ph-4-OCF2CHFOCFThree
H CH (CHThree) CH2SO2Et CFThree              Ph-4-OCF2CHFOCF2CF2CFThree
H CH (CHThree) CH2SO2Et CFThree              Ph-4-O (L-45g)
H CH (CHThree) CH2SO2Et CFThree              Ph-3,4-Cl2
H CH (CHThree) CH2SO2Et CFThree              Ph (-3-OCF2O-4-)
H CH (CHThree) CH2SO2Et CFThree              Ph (-3-OCF2CF2O-4-)
H CH (CHThree) CH2SO2Et CFThree             (L-45c) CFThree
H CH (CHThree) CH2SO2Et CFThree              L-45f
H CH (CHThree) CH2SO2Et CFThree             (L-46c) CFThree
H CH (CHThree) CH2SO2Et CFThree              L-46d
H CH (CHThree) CH2SPr-n CFThree              Ph-4-Br
H CH (CHThree) CH2SPr-n CFThree              Ph-4-CFThree
H CH (CHThree) CH2SPr-n CFThree              Ph-4-OCFThree
H CH (CHThree) CH2SPr-n CFThree             (L-45c) CFThree
H CH (CHThree) CH2SPr-i CFThree             (L-45c) CFThree
H CH (CHThree) CH2SO2Pr-i CFThree              Ph-4-Br
H CH (CHThree) CH2SBu-n CFThree              Ph-4-CFThree
H CH (CHThree) CH2SBu-i CFThree              Ph-4-Br
H CH (CHThree) CH2SBu-i CFThree              Ph-4-CFThree
H CH (CHThree) CH2SBu-i CFThree              Ph-4-OCFThree
H CH (CHThree) CH2SBu-i CFThree             (L-45c) CFThree
H CH (CHThree) CH2SBu-t CFThree              Ph-4-Br
H CH (CHThree) CH2SBu-t CFThree              Ph-4-CFThree
H CH (CHThree) CH2SBu-t CFThree              Ph-4-OCFThree
H CH (CHThree) CH2SBu-t CFThree             (L-45c) CFThree
H CH (CHThree) CH2SO2Bu-t CFThree              Ph-4-OCFThree
H CH (CHThree) CH2SHex-n CFThree             (L-45c) CFThree
H CH (CHThree) CH2SHex-c CFThree              Ph-4-Br
H CH (CHThree) CH2SCH2CFThree            CFThree              Ph-4-CFThree
H CH (CHThree) CH2S (O) CH2CFThree         CFThree              Ph-4-OCFThree
H CH (CHThree) CH2SO2CH2CFThree          CFThree             (L-45c) CFThree
H CH (CHThree) CH2SCH2CH2OH CFThree              Ph-4-Br
H CH (CHThree) CH2SCH2CH2OCHThree        CFThree              Ph-4-CFThree
H CH (CHThree) CH2S (O) CH2CH2OCHThree     CFThree              Ph-4-OCFThree
H CH (CHThree) CH2SO2CH2CH2OCHThree      CFThree             (L-45c) CFThree
H CH (CHThree) CH2SCH2CH2OEt CFThree              Ph-4-Br
H CH (CHThree) CH2S (O) CH2CH2OEt CFThree              Ph-4-CFThree
H CH (CHThree) CH2SO2CH2CH2OEt CFThree              Ph-4-OCFThree
H CH (CHThree) CH2SCH2CH2OC (O) CFThree    CFThree             (L-45c) CFThree
H CH (CHThree) CH2SCH2CH2SCHThree        CFThree              Ph-4-Br
H CH (CHThree) CH2SCH2Si (CHThree)Three       CFThree              Ph-4-Br
H CH (CHThree) CH2SCH2Si (CHThree)Three       CFThree              Ph-4-CFThree
H CH (CHThree) CH2SCH2Si (CHThree)Three       CFThree              Ph-4-OCFThree
H CH (CHThree) CH2SCH2Si (CHThree)Three       CFThree             (L-45c) CFThree
H CH (CHThree) CH2SCH2C (O) CHThree        CFThree              Ph-4-CFThree
H CH (CHThree) CH2SCH2CH2C (O) OCHThree    CFThree              Ph-4-OCFThree
H CH (CHThree) CH2S (O) CH2CH2C (O) OCHThree CFThree             (L-45c) CFThree
H CH (CHThree) CH2SO2CH2CH2C (O) OCHThree  CFThree              Ph-4-Br
H CH (CHThree) CH2SCH2C (O) N (Et)2     CFThree              Ph-4-CFThree
H CH (CHThree) CH2S (O) CH2C (O) N (Et)2  CFThree              Ph-4-OCFThree
H CH (CHThree) CH2SO2CH2C (O) N (Et)2   CFThree             (L-45c) CFThree
H CH (CHThree) CH2SCH2(Ph-2,4-Cl2) CFThree              Ph-4-Br
H CH (CHThree) CH2SCH2CH = CH2         CFThree              Ph-4-CFThree
H CH (CHThree) CH2SCH2C≡CH CFThree              Ph-4-OCFThree
H CH (CHThree) CH2SC (O) CHThree           CFThree             (L-45c) CFThree
H CH (CHThree) CH2SSCHThree              CFThree              CH = CH (Ph-4-Cl)
H CH (CHThree) CH2SSCHThree              CFThree              Ph-4-Cl
H CH (CHThree) CH2SSCHThree              CFThree              Ph-4-Br
H CH (CHThree) CH2SSCHThree              CFThree              Ph-4-CFThree
H CH (CHThree) CH2SSCHThree              CFThree              Ph-4-OCFThree
H CH (CHThree) CH2SSCHThree              CFThree              Ph-4-OCF2Br
H CH (CHThree) CH2SSCHThree              CFThree              Ph-4-OCF2CHFCFThree
H CH (CHThree) CH2SSCHThree              CFThree              Ph-4-OCF2CHFOCFThree
H CH (CHThree) CH2SSCHThree              CFThree              Ph-4-OCF2CHFOCF2CF2CFThree
H CH (CHThree) CH2SSCHThree              CFThree              Ph-4-O (L-45g)
H CH (CHThree) CH2SSCHThree              CFThree              Ph-3,4-Cl2
H CH (CHThree) CH2SSCHThree              CFThree              Ph (-3-OCF2O-4-)
H CH (CHThree) CH2SSCHThree              CFThree              Ph (-3-OCF2CF2O-4-)
H CH (CHThree) CH2SSCHThree              CFThree             (L-45c) CFThree
H CH (CHThree) CH2SSCHThree              CFThree              L-45f
H CH (CHThree) CH2SSCHThree              CFThree             (L-46c) CFThree
H CH (CHThree) CH2SSCHThree              CFThree              L-46d
H CH (CHThree) CH2SS (Ph-2-NO2) CFThree              Ph-4-Br
H CH (CHThree) CH2SO2NH2             CFThree              Ph-4-CFThree
H CH (CHThree) CH2SO2NHCHThree           CFThree              Ph-4-Br
H CH (CHThree) CH2SO2NHCHThree           CFThree              Ph-4-CFThree
H CH (CHThree) CH2SO2NHCHThree           CFThree              Ph-4-OCFThree
H CH (CHThree) CH2SO2NHCHThree           CFThree             (L-45c) CFThree
H CH (CHThree) CH2SO2NHEt CFThree              CF2O (Ph-4-Cl)
H CH (CHThree) CH2SO2NHEt CFThree              CH = CH (Ph-4-Cl)
H CH (CHThree) CH2SO2NHEt CFThree              CH = CH (Ph-4-Br)
H CH (CHThree) CH2SO2NHEt CFThree              CH = CH (Ph-4-CFThree)
H CH (CHThree) CH2SO2NHEt CFThree              CH = CH (Ph-4-OCFThree)
H CH (CHThree) CH2SO2NHEt CFThree              CH = CH (Ph-3,4-Cl2)
H CH (CHThree) CH2SO2NHEt CFThree              Ph-4-F
H CH (CHThree) CH2SO2NHEt CFThree              Ph-4-Cl
H CH (CHThree) CH2SO2NHEt CFThree              Ph-4-Br
H CH (CHThree) CH2SO2NHEt CFThree              Ph-4-CFThree
H CH (CHThree) CH2SO2NHEt CFThree              Ph-4-OCFThree
H CH (CHThree) CH2SO2NHEt (S) CFThree              Ph-4-OCFThree
H CH (CHThree) CH2SO2NHEt CFThree              Ph-4-OCF2Br
H CH (CHThree) CH2SO2NHEt CFThree              Ph-4-OCF2CHF2
H CH (CHThree) CH2SO2NHEt CFThree              Ph-4-OCF2CHFCFThree
H CH (CHThree) CH2SO2NHEt CFThree              Ph-4-OCF2CHFOCFThree
H CH (CHThree) CH2SO2NHEt CFThree              Ph-4-OCF2CHFOCF2CF2CFThree
H CH (CHThree) CH2SO2NHEt CFThree              Ph-4-O (L-45g)
H CH (CHThree) CH2SO2NHEt CFThree              Ph-3,4-F2
H CH (CHThree) CH2SO2NHEt CFThree              Ph-3-F-4-Cl
H CH (CHThree) CH2SO2NHEt CFThree              Ph-3,4-Cl2
H CH (CHThree) CH2SO2NHEt CFThree              Ph (-3-OCF2O-4-)
H CH (CHThree) CH2SO2NHEt CFThree              Ph (-3-OCF2CF2O-4-)
H CH (CHThree) CH2SO2NHEt CFThree             (L-45c) CFThree
H CH (CHThree) CH2SO2NHEt CFThree              L-45f
H CH (CHThree) CH2SO2NHEt CFThree             (L-46c) CFThree
H CH (CHThree) CH2SO2NHEt CFThree              L-46d
H CH (CHThree) CH2SO2NHPr-n CFThree              Ph-4-OCFThree
H CH (CHThree) CH2SO2NHPr-i CFThree             (L-45c) CFThree
H CH (CHThree) CH2SO2NHBu-n CFThree              Ph-4-Br
H CH (CHThree) CH2SO2NHBu-t CFThree              Ph-4-CFThree
H CH (CHThree) CH2SO2NHCH2CH2Cl CFThree              Ph-4-OCFThree
H CH (CHThree) CH2SO2NHCH2CH2OH CFThree             (L-45c) CFThree
H CH (CHThree) CH2SO2NHCH2CH2OCHThree    CFThree              Ph-4-Br
H CH (CHThree) CH2SO2NHCH2CH2SCHThree    CFThree              Ph-4-CFThree
H CH (CHThree) CH2SO2NHCH2CH2S (O) CHThree      CFThree         Ph-4-OCFThree
H CH (CHThree) CH2SO2NHCH2CH2SO2CHThree       CFThree        (L-45c) CFThree
H CH (CHThree) CH2SO2NHCH (CHThree) CH2SCHThree     CFThree         Ph-4-Br
H CH (CHThree) CH2SO2NHCH (CHThree) CH2SCHThree(S, S) CFThree     Ph-4-CFThree
H CH (CHThree) CH2SO2NHCH (CHThree) CH2S (O) CHThree      CFThree     Ph-4-OCFThree
H CH (CHThree) CH2SO2NHCH (CHThree) CH2S (O) CHThree(S, S) CFThree    (L-45c) CFThree
H CH (CHThree) CH2SO2NHCH (CHThree) CH2SO2CHThree       CFThree     Ph-4-Br
H CH (CHThree) CH2SO2NHCH (CHThree) CH2SO2CHThree(S, S) CFThree     Ph-4-CFThree
H CH (CHThree) CH2SO2NHC (CHThree)2CH2SCHThree     CFThree         Ph-4-OCFThree
H CH (CHThree) CH2SO2NHCH (CHThree) C (O) NH2     CFThree        (L-45c) CFThree
H CH (CHThree) CH2SO2NHCH (CHThree) C (O) NHCHThree   CFThree         Ph-4-Br
H CH (CHThree) CH2SO2NHCH (CHThree) C (O) NHEt CFThree         Ph-4-CFThree
H CH (CHThree) CH2SO2NHCH2CH = CH2     CFThree              Ph-4-OCFThree
H CH (CHThree) CH2SO2NHCH2C≡CH CFThree             (L-45c) CFThree
H CH (CHThree) CH2SO2NHCH2Ph CFThree              Ph-4-Br
H CH (CHThree) CH2SO2NHCH2Ph (S) CFThree              Ph-4-CFThree
H CH (CHThree) CH2SO2NHCH2(Ph-2-F) CFThree         Ph-4-OCFThree
H CH (CHThree) CH2SO2NHCH2(Ph-2-Cl) CFThree        (L-45c) CFThree
H CH (CHThree) CH2SO2NHCH2(Ph-2-Br) CFThree         Ph-4-Br
H CH (CHThree) CH2SO2NHCH2(Ph-2-OCHThree) CFThree         Ph-4-CFThree
H CH (CHThree) CH2SO2NHCH2(Ph-3-OCHThree) CFThree         Ph-4-OCFThree
H CH (CHThree) CH2SO2NHCH2(Ph-4-OCHThree) CFThree        (L-45c) CFThree
H CH (CHThree) CH2SO2NHCH2(Ph-4-SCFThree) CFThree         Ph-4-Br
H CH (CHThree) CH2SO2NHCH2(Ph-2-NO2) CFThree         Ph-4-CFThree
H CH (CHThree) CH2SO2NHCH2(Ph-3-NO2) CFThree         Ph-4-OCFThree
H CH (CHThree) CH2SO2NHCH2(Ph-4-NO2) CFThree        (L-45c) CFThree
H CH (CHThree) CH2SO2NHCH2(Ph-3-CN) CFThree         Ph-4-Br
H CH (CHThree) CH2SO2NHCH2(Ph-4-CN) CFThree         Ph-4-CFThree
H CH (CHThree) CH2SO2NHCH2(L-45a) CFThree         Ph-4-OCFThree
H CH (CHThree) CH2SO2NHCH2(L-46a) CFThree        (L-45c) CFThree
H CH (CHThree) CH2SO2NHCH2(L-47a) CFThree         Ph-4-Br
H CH (CHThree) CH2SO2NHCH (CHThree) Ph CFThree         Ph-4-CFThree
H CH (CHThree) CH2SO2NHCH (CHThree) Ph (R) CFThree         Ph-4-OCFThree
H CH (CHThree) CH2SO2NHCH (CHThree) Ph (S) CFThree        (L-45c) CFThree
H CH (CHThree) CH2SO2NHCH2CH2Ph CFThree         Ph-4-Br
H CH (CHThree) CH2SO2NH (Ph-2-OCHThree) CFThree         Ph-4-CFThree
H CH (CHThree) CH2SO2N (CHThree)2         CFThree              Ph-4-Br
H CH (CHThree) CH2SO2N (CHThree)2         CFThree              Ph-4-CFThree
H CH (CHThree) CH2SO2N (CHThree)2         CFThree              Ph-4-OCFThree
H CH (CHThree) CH2SO2N (CHThree)2         CFThree             (L-45c) CFThree
H CH (CHThree) CH2SO2N (CHThree) Et CFThree              Ph-4-OCFThree
H CH (CHThree) CH2SO2N (Et)2          CFThree              CF2O (Ph-4-Cl)
H CH (CHThree) CH2SO2N (Et)2          CFThree              CH = CH (Ph-4-Cl)
H CH (CHThree) CH2SO2N (Et)2          CFThree              CH = CH (Ph-4-Br)
H CH (CHThree) CH2SO2N (Et)2          CFThree              CH = CH (Ph-4-CFThree)
H CH (CHThree) CH2SO2N (Et)2          CFThree              CH = CH (Ph-4-OCFThree)
H CH (CHThree) CH2SO2N (Et)2          CFThree              CH = CH (Ph-3,4-Cl2)
H CH (CHThree) CH2SO2N (Et)2          CFThree              Ph-4-F
H CH (CHThree) CH2SO2N (Et)2          CFThree              Ph-4-Cl
H CH (CHThree) CH2SO2N (Et)2          CFThree              Ph-4-Br
H CH (CHThree) CH2SO2N (Et)2          CFThree              Ph-4-CFThree
H CH (CHThree) CH2SO2N (Et)2          CFThree              Ph-4-OCFThree
H CH (CHThree) CH2SO2N (Et)2(S) CFThree              Ph-4-OCFThree
H CH (CHThree) CH2SO2N (Et)2          CFThree              Ph-4-OCF2Br
H CH (CHThree) CH2SO2N (Et)2          CFThree              Ph-4-OCF2CHF2
H CH (CHThree) CH2SO2N (Et)2          CFThree              Ph-4-OCF2CHFCFThree
H CH (CHThree) CH2SO2N (Et)2          CFThree              Ph-4-OCF2CHFOCFThree
H CH (CHThree) CH2SO2N (Et)2          CFThree              Ph-4-OCF2CHFOCF2CF2CFThree
H CH (CHThree) CH2SO2N (Et)2          CFThree              Ph-4-O (L-45g)
H CH (CHThree) CH2SO2N (Et)2          CFThree              Ph-3,4-F2
H CH (CHThree) CH2SO2N (Et)2          CFThree              Ph-3-F-4-Cl
H CH (CHThree) CH2SO2N (Et)2          CFThree              Ph-3,4-Cl2
H CH (CHThree) CH2SO2N (Et)2          CFThree              Ph (-3-OCF2O-4-)
H CH (CHThree) CH2SO2N (Et)2          CFThree              Ph (-3-OCF2CF2O-4-)
H CH (CHThree) CH2SO2N (Et)2          CFThree             (L-45c) CFThree
H CH (CHThree) CH2SO2N (Et)2          CFThree              L-45f
H CH (CHThree) CH2SO2N (Et)2          CFThree             (L-46c) CFThree
H CH (CHThree) CH2SO2N (Et)2          CFThree              L-46d
H CH (CHThree) CH2SO2(T-19) CFThree             (L-45c) CFThree
H CH (CHThree) CH2SO2(T-20) CFThree              Ph-4-Br
H CH (CHThree) CH2SO2(T-21) CFThree              Ph-4-CFThree
H CH (CHThree) CH2SO2N (CHThree) CH2Ph CFThree              Ph-4-OCFThree
H CH (CHThree) CH2SO2N (Et) CH2Ph CFThree             (L-45c) CFThree
H CH (CHThree) CH2SC (O) NHEt CFThree              Ph-4-Br
H CH (CHThree) CH2SC (O) N (CHThree)2       CFThree              Ph-4-CFThree
H CH (CHThree) CH2SC (O) N (Et)2        CFThree              Ph-4-OCFThree
H CH (CHThree) CH2SC (S) NHCHThree         CFThree             (L-45c) CFThree
H CH (CHThree) CH2SC (S) NHEt CFThree              Ph-4-Br
H CH (CHThree) CH2SC (S) N (CHThree)2       CFThree              Ph-4-CFThree
H CH (CHThree) CH2SPh CFThree              Ph-4-Br
H CH (CHThree) CH2SPh CFThree              Ph-4-CFThree
H CH (CHThree) CH2SPh CFThree              Ph-4-OCFThree
H CH (CHThree) CH2SPh CFThree             (L-45c) CFThree
H CH (CHThree) CH2S (L-21a) CFThree              Ph-4-OCFThree
H CH (CHThree) CH2SO2(L-21a) CFThree             (L-45c) CFThree
H CH (CHThree) CH2S (L-45a) CFThree              Ph-4-Br
H CH (CHThree) CH2S (L-45a) CFThree              Ph-4-CFThree
H CH (CHThree) CH2S (L-45a) CFThree              Ph-4-OCFThree
H CH (CHThree) CH2S (L-45a) CFThree             (L-45c) CFThree
H CH (CHThree) CH2S (O) (L-45a) CFThree              Ph-4-Br
H CH (CHThree) CH2S (O) (L-45a) CFThree              Ph-4-CFThree
H CH (CHThree) CH2S (O) (L-45a) CFThree              Ph-4-OCFThree
H CH (CHThree) CH2S (O) (L-45a) CFThree             (L-45c) CFThree
H CH (CHThree) CH2SO2(L-45a) CFThree              Ph-4-Br
H CH (CHThree) CH2SO2(L-45a) CFThree              Ph-4-CFThree
H CH (CHThree) CH2SO2(L-45a) CFThree              Ph-4-OCFThree
H CH (CHThree) CH2SO2(L-45a) CFThree             (L-45c) CFThree
H CH (CHThree) CH2S (L-48a) CFThree              Ph-4-Br
H CH (CHThree) CH2S (O) (L-48a) CFThree              Ph-4-CFThree
H CH (CHThree) CH2SO2(L-48a) CFThree              Ph-4-OCFThree
H CH (CHThree) CH2S (L-48b) CFThree             (L-45c) CFThree
H CH (CHThree) CH2S (O) (L-48b) CFThree              Ph-4-Br
H CH (CHThree) CH2SO2(L-48b) CFThree              Ph-4-CFThree
H CH (Et) CH2SCHThree                CFThree             (L-45c) CFThree
H CH (CH2SCHThree)2                 CFThree              Ph-4-Br
H CH (Ph) CH2SCHThree                CFThree              Ph-4-CFThree
H CH (Ph) CH2S (O) CHThree             CFThree              Ph-4-OCFThree
H CH (Ph) CH2SO2CHThree              CFThree             (L-45c) CFThree
H CH (CHThree) CH (CHThree) SCHThree           CFThree              Ph-4-Br
H CH (CHThree) CH (CHThree) SO2CHThree         CFThree              Ph-4-CFThree
H CH (CHThree) CH (CHThree) SEt CFThree              Ph-4-OCFThree
H CH (CHThree) CH (CHThree) SO2Et CFThree             (L-45c) CFThree
H C (CHThree)2CH2SCHThree               CHThree              CF2O (Ph-4-Cl)
H C (CHThree)2CH2SCHThree               CHThree              CH = CH (Ph-4-Cl)
H C (CHThree)2CH2SCHThree               CHThree              CH = CH (Ph-4-OCFThree)
H C (CHThree)2CH2SCHThree               CHThree              CH = CH (Ph-3,4-Cl2)
H C (CHThree)2CH2SCHThree               CHThree              Ph-4-F
H C (CHThree)2CH2SCHThree               CHThree              Ph-4-Cl
H C (CHThree)2CH2SCHThree               CHThree              Ph-4-Br
H C (CHThree)2CH2SCHThree               CHThree              Ph-4-I
H C (CHThree)2CH2SCHThree               CHThree              Ph-4-CFThree
H C (CHThree)2CH2SCHThree               CHThree              Ph-4-OCHF2
H C (CHThree)2CH2SCHThree               CHThree              Ph-4-OCFThree
H C (CHThree)2CH2SCHThree               CHThree              Ph-4-OCF2Br
H C (CHThree)2CH2SCHThree               CHThree              Ph-4-OCF2CHF2
H C (CHThree)2CH2SCHThree               CHThree              Ph-4-OCF2CHFCl
H C (CHThree)2CH2SCHThree               CHThree              Ph-4-OCF2CHFCFThree
H C (CHThree)2CH2SCHThree               CHThree              Ph-4-OCF2CHFOCFThree
H C (CHThree)2CH2SCHThree               CHThree              Ph-4-OCF2CHFOCF2CF2CFThree
H C (CHThree)2CH2SCHThree               CHThree              Ph-4-O (L-45g)
H C (CHThree)2CH2SCHThree               CHThree              Ph-3,4-Cl2
H C (CHThree)2CH2SCHThree               CHThree              Ph (-3-OCF2O-4-)
H C (CHThree)2CH2SCHThree               CHThree              Ph (-3-OCF2CF2O-4-)
H C (CHThree)2CH2SCHThree               CHThree             (L-45c) Cl
H C (CHThree)2CH2SCHThree               CHThree             (L-45c) Br
H C (CHThree)2CH2SCHThree               CHThree             (L-45c) CFThree
H C (CHThree)2CH2SCHThree               CHThree              L-45e
H C (CHThree)2CH2SCHThree               CHThree              L-45f
H C (CHThree)2CH2SCHThree               CHThree             (L-46c) Cl
H C (CHThree)2CH2SCHThree               CHThree             (L-46c) Br
H C (CHThree)2CH2SCHThree               CHThree             (L-46c) CFThree
H C (CHThree)2CH2SCHThree               CHThree              L-46d
H C (CHThree)2CH2SCHThree               Et Ph-4-Cl
H C (CHThree)2CH2SCHThree               Et Ph-4-Br
H C (CHThree)2CH2SCHThree               Et Ph-4-CFThree
H C (CHThree)2CH2SCHThree               Et Ph-4-OCFThree
H C (CHThree)2CH2SCHThree               Et Ph-4-OCF2Br
H C (CHThree)2CH2SCHThree               Et Ph-4-OCF2CHFCFThree
H C (CHThree)2CH2SCHThree               Et Ph-4-OCF2CHFOCFThree
H C (CHThree)2CH2SCHThree               Et Ph-4-OCF2CHFOCF2CF2CFThree
H C (CHThree)2CH2SCHThree               Et Ph-4-O (L-45g)
H C (CHThree)2CH2SCHThree               Et Ph-3,4-Cl2
H C (CHThree)2CH2SCHThree               Et Ph (-3-OCF2O-4-)
H C (CHThree)2CH2SCHThree               Et Ph (-3-OCF2CF2O-4-)
H C (CHThree)2CH2SCHThree               Et (L-45c) CFThree
H C (CHThree)2CH2SCHThree               n-Pr Ph-4-Br
H C (CHThree)2CH2SCHThree               n-Pr Ph-4-CFThree
H C (CHThree)2CH2SCHThree               n-Pr Ph-4-OCFThree
H C (CHThree)2CH2SCHThree               n-Pr (L-45c) CFThree
H C (CHThree)2CH2SCHThree               i-Pr Ph-4-Br
H C (CHThree)2CH2SCHThree               i-Pr Ph-4-CFThree
H C (CHThree)2CH2SCHThree               i-Pr Ph-4-OCFThree
H C (CHThree)2CH2SCHThree               i-Pr (L-45c) CFThree
H C (CHThree)2CH2SCHThree               c-Pr Ph-4-Br
H C (CHThree)2CH2SCHThree               c-Pr Ph-4-CFThree
H C (CHThree)2CH2SCHThree               c-Pr Ph-4-OCFThree
H C (CHThree)2CH2SCHThree               c-Pr (L-45c) CFThree
H C (CHThree)2CH2SCHThree               n-Bu Ph-4-Br
H C (CHThree)2CH2SCHThree               CH2F Ph-4-CFThree
H C (CHThree)2CH2SCHThree               CH2Cl Ph-4-OCFThree
H C (CHThree)2CH2SCHThree               CH2Br (L-45c) CFThree
H C (CHThree)2CH2SCHThree               CHF2             Ph-4-Cl
H C (CHThree)2CH2SCHThree               CHF2             Ph-4-Br
H C (CHThree)2CH2SCHThree               CHF2             Ph-4-CFThree
H C (CHThree)2CH2SCHThree               CHF2             Ph-4-OCFThree
H C (CHThree)2CH2SCHThree               CHF2             Ph-4-OCF2Br
H C (CHThree)2CH2SCHThree               CHF2             Ph-4-OCF2CHFCFThree
H C (CHThree)2CH2SCHThree               CHF2             Ph-4-OCF2CHFOCFThree
H C (CHThree)2CH2SCHThree               CHF2             Ph-4-OCF2CHFOCF2CF2CFThree
H C (CHThree)2CH2SCHThree               CHF2             Ph-4-O (L-45g)
H C (CHThree)2CH2SCHThree               CHF2             Ph-3,4-Cl2
H C (CHThree)2CH2SCHThree               CHF2             Ph (-3-OCF2O-4-)
H C (CHThree)2CH2SCHThree               CHF2             Ph (-3-OCF2CF2O-4-)
H C (CHThree)2CH2SCHThree               CHF2            (L-45c) CFThree
H C (CHThree)2CH2SCHThree               CHF2             L-45f
H C (CHThree)2CH2SCHThree               CHF2            (L-46c) CFThree
H C (CHThree)2CH2SCHThree               CHF2             L-46d
H C (CHThree)2CH2SCHThree               CHFCl Ph-4-Br
H C (CHThree)2CH2SCHThree               CHFBr Ph-4-CFThree
H C (CHThree)2CH2SCHThree               CFThree              c-Pr
H C (CHThree)2CH2SCHThree               CFThree              c-Bu
H C (CHThree)2CH2SCHThree               CFThree              c-Pen
H C (CHThree)2CH2SCHThree               CFThree              c-Hex
H C (CHThree)2CH2SCHThree               CFThree              T-1
H C (CHThree)2CH2SCHThree               CFThree              T-2
H C (CHThree)2CH2SCHThree               CFThree              T-3
H C (CHThree)2CH2SCHThree               CFThree              T-4
H C (CHThree)2CH2SCHThree               CFThree              T-5
H C (CHThree)2CH2SCHThree               CFThree              CH2OCHThree
H C (CHThree)2CH2SCHThree               CFThree              CH2OEt
H C (CHThree)2CH2SCHThree               CFThree              CH2OPr-n
H C (CHThree)2CH2SCHThree               CFThree              CH2OPr-i
H C (CHThree)2CH2SCHThree               CFThree              CH2OBu-n
H C (CHThree)2CH2SCHThree               CFThree              CH2OC (O) (Ph-2-Cl)
H C (CHThree)2CH2SCHThree               CFThree              CH2OC (O) (Ph-3-Cl)
H C (CHThree)2CH2SCHThree               CFThree              CH2OC (O) (Ph-4-Cl)
H C (CHThree)2CH2SCHThree               CFThree              CH2OPh
H C (CHThree)2CH2SCHThree               CFThree              CH2O (Ph-2-F)
H C (CHThree)2CH2SCHThree               CFThree              CH2O (Ph-3-F)
H C (CHThree)2CH2SCHThree               CFThree              CH2O (Ph-4-F)
H C (CHThree)2CH2SCHThree               CFThree              CH2O (Ph-2-Cl)
H C (CHThree)2CH2SCHThree               CFThree              CH2O (Ph-3-Cl)
H C (CHThree)2CH2SCHThree               CFThree              CH2O (Ph-4-Cl)
H C (CHThree)2CH2SCHThree               CFThree              CH2O (Ph-2-Br)
H C (CHThree)2CH2SCHThree               CFThree              CH2O (Ph-3-Br)
H C (CHThree)2CH2SCHThree               CFThree              CH2O (Ph-4-Br)
H C (CHThree)2CH2SCHThree               CFThree              CH2O (Ph-2-CFThree)
H C (CHThree)2CH2SCHThree               CFThree              CH2O (Ph-3-CFThree)
H C (CHThree)2CH2SCHThree               CFThree              CH2O (Ph-4-CFThree)
H C (CHThree)2CH2SCHThree               CFThree              CH2O (Ph-2-OCFThree)
H C (CHThree)2CH2SCHThree               CFThree              CH2O (Ph-3-OCFThree)
H C (CHThree)2CH2SCHThree               CFThree              CH2O (Ph-4-OCFThree)
H C (CHThree)2CH2SCHThree               CFThree              CF2OPh
H C (CHThree)2CH2SCHThree               CFThree              CF2O (Ph-2-F)
H C (CHThree)2CH2SCHThree               CFThree              CF2O (Ph-3-F)
H C (CHThree)2CH2SCHThree               CFThree              CF2O (Ph-4-F)
H C (CHThree)2CH2SCHThree               CFThree              CF2O (Ph-2-Cl)
H C (CHThree)2CH2SCHThree               CFThree              CF2O (Ph-3-Cl)
H C (CHThree)2CH2SCHThree               CFThree              CF2O (Ph-4-Cl)
H C (CHThree)2CH2SCHThree               CFThree              CF2O (Ph-2-Br)
H C (CHThree)2CH2SCHThree               CFThree              CF2O (Ph-3-Br)
H C (CHThree)2CH2SCHThree               CFThree              CF2O (Ph-4-Br)
H C (CHThree)2CH2SCHThree               CFThree              CF2O (Ph-2-CFThree)
H C (CHThree)2CH2SCHThree               CFThree              CF2O (Ph-3-CFThree)
H C (CHThree)2CH2SCHThree               CFThree              CF2O (Ph-4-CFThree)
H C (CHThree)2CH2SCHThree               CFThree              CF2O (Ph-2-OCFThree)
H C (CHThree)2CH2SCHThree               CFThree              CF2O (Ph-3-OCFThree)
H C (CHThree)2CH2SCHThree               CFThree              CF2O (Ph-4-OCFThree)
H C (CHThree)2CH2SCHThree               CFThree              CH2S (Ph-2-Cl)
H C (CHThree)2CH2SCHThree               CFThree              CH2S (Ph-3-Cl)
H C (CHThree)2CH2SCHThree               CFThree              CH2S (Ph-4-Cl)
H C (CHThree)2CH2SCHThree               CFThree              CH2SO2(Ph-2-Cl)
H C (CHThree)2CH2SCHThree               CFThree              CH2SO2(Ph-3-Cl)
H C (CHThree)2CH2SCHThree               CFThree              CH2SO2(Ph-4-Cl)
H C (CHThree)2CH2SCHThree               CFThree              CH2N (CHThree)2
H C (CHThree)2CH2SCHThree               CFThree              CH2NH (Ph-2-Cl)
H C (CHThree)2CH2SCHThree               CFThree              CH2NH (Ph-3-Cl)
H C (CHThree)2CH2SCHThree               CFThree              CH2NH (Ph-4-Cl)
H C (CHThree)2CH2SCHThree               CFThree              CF2C (O) OEt
H C (CHThree)2CH2SCHThree               CFThree              CH2(L-5a)
H C (CHThree)2CH2SCHThree               CFThree              CH2(L-14a)
H C (CHThree)2CH2SCHThree               CFThree              CH2(L-24a)
H C (CHThree)2CH2SCHThree               CFThree              CH2(L-36a)
H C (CHThree)2CH2SCHThree               CFThree              CH2CH2Ph
H C (CHThree)2CH2SCHThree               CFThree              CH2CH2(Ph-2-Cl)
H C (CHThree)2CH2SCHThree               CFThree              CH2CH2(Ph-3-Cl)
H C (CHThree)2CH2SCHThree               CFThree              CH2CH2(Ph-4-Cl)
H C (CHThree)2CH2SCHThree               CFThree              T-22
H C (CHThree)2CH2SCHThree               CFThree              T-23
H C (CHThree)2CH2SCHThree               CFThree              T-24
H C (CHThree)2CH2SCHThree               CFThree              C (O) OEt
H C (CHThree)2CH2SCHThree               CFThree              C (O) OBu-t
H C (CHThree)2CH2SCHThree               CFThree              C (O) OCH2CFThree
H C (CHThree)2CH2SCHThree               CFThree              CH = CH (Ph-2-F)
H C (CHThree)2CH2SCHThree               CFThree              CH = CH (Ph-3-F)
H C (CHThree)2CH2SCHThree               CFThree              CH = CH (Ph-4-F)
H C (CHThree)2CH2SCHThree               CFThree              CH = CH (Ph-2-Cl)
H C (CHThree)2CH2SCHThree               CFThree              CH = CH (Ph-3-Cl)
H C (CHThree)2CH2SCHThree               CFThree              CH = CH (Ph-4-Cl)
H C (CHThree)2CH2SCHThree               CFThree              CH = CH (Ph-2-Br)
H C (CHThree)2CH2SCHThree               CFThree              CH = CH (Ph-3-Br)
H C (CHThree)2CH2SCHThree               CFThree              CH = CH (Ph-4-Br)
H C (CHThree)2CH2SCHThree               CFThree              CH = CH (Ph-2-CFThree)
H C (CHThree)2CH2SCHThree               CFThree              CH = CH (Ph-3-CFThree)
H C (CHThree)2CH2SCHThree               CFThree              CH = CH (Ph-4-CFThree)
H C (CHThree)2CH2SCHThree               CFThree              CH = CH (Ph-2-OCFThree)
H C (CHThree)2CH2SCHThree               CFThree              CH = CH (Ph-3-OCFThree)
H C (CHThree)2CH2SCHThree               CFThree              CH = CH (Ph-4-OCFThree)
H C (CHThree)2CH2SCHThree               CFThree              CH = CH (Ph-2-SCHThree)
H C (CHThree)2CH2SCHThree               CFThree              CH = CH (Ph-3-SCHThree)
H C (CHThree)2CH2SCHThree               CFThree              CH = CH (Ph-4-SCHThree)
H C (CHThree)2CH2SCHThree               CFThree              CH = CH (Ph-2-SO2CHThree)
H C (CHThree)2CH2SCHThree               CFThree              CH = CH (Ph-3-SO2CHThree)
H C (CHThree)2CH2SCHThree               CFThree              CH = CH (Ph-4-SO2CHThree)
H C (CHThree)2CH2SCHThree               CFThree              CH = CH (Ph-3,4-F2)
H C (CHThree)2CH2SCHThree               CFThree              CH = CH (Ph-3-F-4-Cl)
H C (CHThree)2CH2SCHThree               CFThree              CH = CH (Ph-3,4-Cl2)
H C (CHThree)2CH2SCHThree               CFThree              CH = CH (Ph-3,4-Br2)
H C (CHThree)2CH2SCHThree               CFThree              CH = CH (Ph-3-F-4-CFThree)
H C (CHThree)2CH2SCHThree               CFThree              CH = CH (Ph-3-Cl-4-OCFThree)
H C (CHThree)2CH2SCHThree               CFThree              CH = CH [Ph (-3-OCF2O-4-)]
H C (CHThree)2CH2SCHThree               CFThree              Ph
H C (CHThree)2CH2SCHThree               CFThree              Ph-2-F
H C (CHThree)2CH2SCHThree               CFThree              Ph-3-F
H C (CHThree)2CH2SCHThree               CFThree              Ph-4-F
H C (CHThree)2CH2SCHThree               CFThree              Ph-2-Cl
H C (CHThree)2CH2SCHThree               CFThree              Ph-3-Cl
H C (CHThree)2CH2SCHThree               CFThree              Ph-4-Cl
H C (CHThree)2CH2SCHThree               CFThree              Ph-2-Br
H C (CHThree)2CH2SCHThree               CFThree              Ph-3-Br
H C (CHThree)2CH2SCHThree               CFThree              Ph-4-Br
H C (CHThree)2CH2SCHThree               CFThree              Ph-4-I
H C (CHThree)2CH2SCHThree               CFThree              Ph-4-Bu-t
H C (CHThree)2CH2SCHThree               CFThree              Ph-2-CFThree
H C (CHThree)2CH2SCHThree               CFThree              Ph-3-CFThree
H C (CHThree)2CH2SCHThree               CFThree              Ph-4-CFThree
H C (CHThree)2CH2SCHThree               CFThree              Ph-4-OCHThree
H C (CHThree)2CH2SCHThree               CFThree              Ph-4-OCHF2
H C (CHThree)2CH2SCHThree               CFThree              Ph-2-OCFThree
H C (CHThree)2CH2SCHThree               CFThree              Ph-3-OCFThree
H C (CHThree)2CH2SCHThree               CFThree              Ph-4-OCFThree
H C (CHThree)2CH2SCHThree               CFThree              Ph-4-OCF2Br
H C (CHThree)2CH2SCHThree               CFThree              Ph-4-OCH2CFThree
H C (CHThree)2CH2SCHThree               CFThree              Ph-4-OCF2CHF2
H C (CHThree)2CH2SCHThree               CFThree              Ph-4-OCF2CHFCl
H C (CHThree)2CH2SCHThree               CFThree              Ph-4-OCF2CHFBr
H C (CHThree)2CH2SCHThree               CFThree              Ph-4-OCF2CF2Br
H C (CHThree)2CH2SCHThree               CFThree              Ph-4-OCF2CFCl2
H C (CHThree)2CH2SCHThree               CFThree              Ph-4-OCF2CClThree
H C (CHThree)2CH2SCHThree               CFThree              Ph-4-OCH2CF2CHF2
H C (CHThree)2CH2SCHThree               CFThree              Ph-3-OCF2CHFCFThree
H C (CHThree)2CH2SCHThree               CFThree              Ph-4-OCF2CHFCFThree
H C (CHThree)2CH2SCHThree               CFThree              Ph-4-OCH (CFThree)2
H C (CHThree)2CH2SCHThree               CFThree              Ph-4-OCF2CFBrCFThree
H C (CHThree)2CH2SCHThree               CFThree              Ph-3-OCF2CHFOCFThree
H C (CHThree)2CH2SCHThree               CFThree              Ph-4-OCF2CHFOCFThree
H C (CHThree)2CH2SCHThree               CFThree              Ph-4-OCF2CHFOCF2CF2CFThree
H C (CHThree)2CH2SCHThree               CFThree              Ph-4-OSO2CHThree
H C (CHThree)2CH2SCHThree               CFThree              Ph-4-OSO2CFThree
H C (CHThree)2CH2SCHThree               CFThree              Ph-3-O (Ph-4-Cl)
H C (CHThree)2CH2SCHThree               CFThree              Ph-4-O (Ph-4-Cl)
H C (CHThree)2CH2SCHThree               CFThree              Ph-4-O (Ph-4-Br)
H C (CHThree)2CH2SCHThree               CFThree              Ph-4-O (Ph-4-CFThree)
H C (CHThree)2CH2SCHThree               CFThree              Ph-4-O (L-45c) Br
H C (CHThree)2CH2SCHThree               CFThree              Ph-4-O (L-45c) CFThree
H C (CHThree)2CH2SCHThree               CFThree              Ph-3-O (L-45e)
H C (CHThree)2CH2SCHThree               CFThree              Ph-4-O (L-45e)
H C (CHThree)2CH2SCHThree               CFThree              Ph-4-O (L-48b) Br
H C (CHThree)2CH2SCHThree               CFThree              Ph-4-SCHThree
H C (CHThree)2CH2SCHThree               CFThree              Ph-4-SO2CHThree
H C (CHThree)2CH2SCHThree               CFThree              Ph-3-S (Ph-4-Cl)
H C (CHThree)2CH2SCHThree               CFThree              Ph-4-S (Ph-4-Cl)
H C (CHThree)2CH2SCHThree               CFThree              Ph-4-S (Ph-4-Br)
H C (CHThree)2CH2SCHThree               CFThree              Ph-4-S (Ph-4-CFThree)
H C (CHThree)2CH2SCHThree               CFThree              Ph-4-S (L-45c) Br
H C (CHThree)2CH2SCHThree               CFThree              Ph-4-S (L-45c) CFThree
H C (CHThree)2CH2SCHThree               CFThree              Ph-4-S (L-45e)
H C (CHThree)2CH2SCHThree               CFThree              Ph-4-S (L-48b) Br
H C (CHThree)2CH2SCHThree               CFThree              Ph-4-NO2
H C (CHThree)2CH2SCHThree               CFThree              Ph-4-CN
H C (CHThree)2CH2SCHThree               CFThree              Ph-2,3-F2
H C (CHThree)2CH2SCHThree               CFThree              Ph-2,4-F2
H C (CHThree)2CH2SCHThree               CFThree              Ph-3,4-F2
H C (CHThree)2CH2SCHThree               CFThree              Ph-2,5-F2
H C (CHThree)2CH2SCHThree               CFThree              Ph-3,5-F2
H C (CHThree)2CH2SCHThree               CFThree              Ph-2-Cl-4-F
H C (CHThree)2CH2SCHThree               CFThree              Ph-2-F-3-Cl
H C (CHThree)2CH2SCHThree               CFThree              Ph-3-Cl-4-F
H C (CHThree)2CH2SCHThree               CFThree              Ph-2-F-4-Cl
H C (CHThree)2CH2SCHThree               CFThree              Ph-3-F-4-Cl
H C (CHThree)2CH2SCHThree               CFThree              Ph-2,3-Cl2
H C (CHThree)2CH2SCHThree               CFThree              Ph-2,4-Cl2
H C (CHThree)2CH2SCHThree               CFThree              Ph-2,5-Cl2
H C (CHThree)2CH2SCHThree               CFThree              Ph-3,4-Cl2
H C (CHThree)2CH2SCHThree               CFThree              Ph-3,5-Cl2
H C (CHThree)2CH2SCHThree               CFThree              Ph-3-Br-4-F
H C (CHThree)2CH2SCHThree               CFThree              Ph-2-F-4-Br
H C (CHThree)2CH2SCHThree               CFThree              Ph-2-F-5-Br
H C (CHThree)2CH2SCHThree               CFThree              Ph-3,4-Br2
H C (CHThree)2CH2SCHThree               CFThree              Ph-3,5-Br2
H C (CHThree)2CH2SCHThree               CFThree              Ph-3-CHThree-4-F
H C (CHThree)2CH2SCHThree               CFThree              Ph-3-F-4-CHThree
H C (CHThree)2CH2SCHThree               CFThree              Ph-2-F-5-CHThree
H C (CHThree)2CH2SCHThree               CFThree              Ph-2,4- (CHThree)2
H C (CHThree)2CH2SCHThree               CFThree              Ph-3,4- (CHThree)2
H C (CHThree)2CH2SCHThree               CFThree              Ph-2-F-3-CFThree
H C (CHThree)2CH2SCHThree               CFThree              Ph-3-CFThree-4-F
H C (CHThree)2CH2SCHThree               CFThree              Ph-3-CFThree-4-Cl
H C (CHThree)2CH2SCHThree               CFThree              Ph-2-F-4-CFThree
H C (CHThree)2CH2SCHThree               CFThree              Ph-3-F-4-CFThree
H C (CHThree)2CH2SCHThree               CFThree              Ph-2-F-5-CFThree
H C (CHThree)2CH2SCHThree               CFThree              Ph-3-F-5-CFThree
H C (CHThree)2CH2SCHThree               CFThree              Ph-2-Cl-4-CFThree
H C (CHThree)2CH2SCHThree               CFThree              Ph-3,5- (CFThree)2
H C (CHThree)2CH2SCHThree               CFThree              Ph-3-Br-4-OCHThree
H C (CHThree)2CH2SCHThree               CFThree              Ph-3-F-4-OCHF2
H C (CHThree)2CH2SCHThree               CFThree              Ph-3-Cl-4-OCHF2
H C (CHThree)2CH2SCHThree               CFThree              Ph-3-Br-4-OCHF2
H C (CHThree)2CH2SCHThree               CFThree              Ph-3-F-4-OCFThree
H C (CHThree)2CH2SCHThree               CFThree              Ph-3-Cl-4-OCFThree
H C (CHThree)2CH2SCHThree               CFThree              Ph-3-Br-4-OCFThree
H C (CHThree)2CH2SCHThree               CFThree              Ph-3-F-4-OCF2Br
H C (CHThree)2CH2SCHThree               CFThree              Ph-3-Cl-4-OCF2Br
H C (CHThree)2CH2SCHThree               CFThree              Ph-3-Br-4-OCF2Br
H C (CHThree)2CH2SCHThree               CFThree              Ph-3-F-4-OCF2CHF2
H C (CHThree)2CH2SCHThree               CFThree              Ph-3-Cl-4-OCF2CHF2
H C (CHThree)2CH2SCHThree               CFThree              Ph-3-Br-4-OCF2CHF2
H C (CHThree)2CH2SCHThree               CFThree              Ph-3-F-4-OCF2CHFCl
H C (CHThree)2CH2SCHThree               CFThree              Ph-3-Cl-4-OCF2CHFCl
H C (CHThree)2CH2SCHThree               CFThree              Ph-3-Br-4-OCF2CHFCl
H C (CHThree)2CH2SCHThree               CFThree              Ph-3-F-4-OCF2CHFCFThree
H C (CHThree)2CH2SCHThree               CFThree              Ph-3-Cl-4-OCF2CHFCFThree
H C (CHThree)2CH2SCHThree               CFThree              Ph-3-Br-4-OCF2CHFCFThree
H C (CHThree)2CH2SCHThree               CFThree              Ph-3-F-4-OCF2CHFOCFThree
H C (CHThree)2CH2SCHThree               CFThree              Ph-3-Cl-4-OCF2CHFOCFThree
H C (CHThree)2CH2SCHThree               CFThree              Ph-3-Br-4-OCF2CHFOCFThree
H C (CHThree)2CH2SCHThree               CFThree              Ph-3-CHThree-4-OCF2CHFOCFThree
H C (CHThree)2CH2SCHThree               CFThree         Ph-3-F-4-OCF2CHFOCF2CF2CFThree
H C (CHThree)2CH2SCHThree               CFThree         Ph-3-Cl-4-OCF2CHFOCF2CF2CFThree
H C (CHThree)2CH2SCHThree               CFThree         Ph-3-Br-4-OCF2CHFOCF2CF2CFThree
H C (CHThree)2CH2SCHThree               CFThree              Ph (-3-OCF2O-4-)
H C (CHThree)2CH2SCHThree               CFThree              Ph (-3-OCF2CF2O-4-)
H C (CHThree)2CH2SCHThree               CFThree              Ph-3-OPh-4-F
H C (CHThree)2CH2SCHThree               CFThree              Ph-3-NO2-4-F
H C (CHThree)2CH2SCHThree               CFThree              Ph-3-NO2-4-Cl
H C (CHThree)2CH2SCHThree               CFThree              Ph-2-F-5-NO2
H C (CHThree)2CH2SCHThree               CFThree              Ph-3-CN-4-F
H C (CHThree)2CH2SCHThree               CFThree              Ph-2,3,4-FThree
H C (CHThree)2CH2SCHThree               CFThree              Ph-2,3,5-FThree
H C (CHThree)2CH2SCHThree               CFThree              Ph-2,4,5-FThree
H C (CHThree)2CH2SCHThree               CFThree              Ph-3,4,5-FThree
H C (CHThree)2CH2SCHThree               CFThree              Ph-2,3-F2-4-CHThree
H C (CHThree)2CH2SCHThree               CFThree              Ph-2,3-F2-4-CFThree
H C (CHThree)2CH2SCHThree               CFThree              Ph-3,4-F2-5-CFThree
H C (CHThree)2CH2SCHThree               CFThree              Ph-2-F-3-Cl-5-CFThree
H C (CHThree)2CH2SCHThree               CFThree              Ph-3,5-Cl2-4-OCHThree
H C (CHThree)2CH2SCHThree               CFThree              1-Naph
H C (CHThree)2CH2SCHThree               CFThree              2-Naph
H C (CHThree)2CH2SCHThree               CFThree             (L-1b) Br
H C (CHThree)2CH2SCHThree               CFThree             (L-1c) Cl
H C (CHThree)2CH2SCHThree               CFThree             (L-1c) Br
H C (CHThree)2CH2SCHThree               CFThree             (L-1c) I
H C (CHThree)2CH2SCHThree               CFThree             (L-1c) CFThree
H C (CHThree)2CH2SCHThree               CFThree             (L-2b) Br
H C (CHThree)2CH2SCHThree               CFThree             (L-3b) Cl
H C (CHThree)2CH2SCHThree               CFThree             (L-3b) Br
H C (CHThree)2CH2SCHThree               CFThree             (L-3c) F
H C (CHThree)2CH2SCHThree               CFThree             (L-3c) Cl
H C (CHThree)2CH2SCHThree               CFThree             (L-3c) Br
H C (CHThree)2CH2SCHThree               CFThree             (L-3c) I
H C (CHThree)2CH2SCHThree               CFThree             (L-3c) CFThree
H C (CHThree)2CH2SCHThree               CFThree             (L-3c) CN
H C (CHThree)2CH2SCHThree               CFThree              L-3d
H C (CHThree)2CH2SCHThree               CFThree             (L-4b) Cl
H C (CHThree)2CH2SCHThree               CFThree             (L-4b) Br
H C (CHThree)2CH2SCHThree               CFThree             (L-4b) CN
H C (CHThree)2CH2SCHThree               CFThree             (L-10b) Cl
H C (CHThree)2CH2SCHThree               CFThree             (L-10b) Br
H C (CHThree)2CH2SCHThree               CFThree             (L-15b) CFThree
H C (CHThree)2CH2SCHThree               CFThree             (L-16a) CHF2
H C (CHThree)2CH2SCHThree               CFThree             (L-16a) CF2Br
H C (CHThree)2CH2SCHThree               CFThree             (L-17a) Cl
H C (CHThree)2CH2SCHThree               CFThree             (L-21b) Cl
H C (CHThree)2CH2SCHThree               CFThree             (L-21b) Br
H C (CHThree)2CH2SCHThree               CFThree             (L-21b) I
H C (CHThree)2CH2SCHThree               CFThree             (L-21b) CFThree
H C (CHThree)2CH2SCHThree               CFThree             (L-22b) Cl
H C (CHThree)2CH2SCHThree               CFThree             (L-22b) Br
H C (CHThree)2CH2SCHThree               CFThree             (L-23b) Cl
H C (CHThree)2CH2SCHThree               CFThree             (L-23b) Br
H C (CHThree)2CH2SCHThree               CFThree             (L-23c) Cl
H C (CHThree)2CH2SCHThree               CFThree             (L-23c) Br
H C (CHThree)2CH2SCHThree               CFThree             (L-31a) Cl
H C (CHThree)2CH2SCHThree               CFThree             (L-31a) Br
H C (CHThree)2CH2SCHThree               CFThree             (L-45c) F
H C (CHThree)2CH2SCHThree               CFThree             (L-45c) Cl
H C (CHThree)2CH2SCHThree               CFThree             (L-45c) Br
H C (CHThree)2CH2SCHThree               CFThree             (L-45c) I
H C (CHThree)2CH2SCHThree               CFThree             (L-45c) CFThree
H C (CHThree)2CH2SCHThree               CFThree              L-45e
H C (CHThree)2CH2SCHThree               CFThree              L-45f
H C (CHThree)2CH2SCHThree               CFThree             (L-46c) F
H C (CHThree)2CH2SCHThree               CFThree             (L-46c) Cl
H C (CHThree)2CH2SCHThree               CFThree             (L-46c) Br
H C (CHThree)2CH2SCHThree               CFThree             (L-46c) I
H C (CHThree)2CH2SCHThree               CFThree             (L-46c) CFThree
H C (CHThree)2CH2SCHThree               CFThree             (L-46c) OCH2CFThree
H C (CHThree)2CH2SCHThree               CFThree             (L-46c) OCH (CFThree)2
H C (CHThree)2CH2SCHThree               CFThree              L-46d
H C (CHThree)2CH2SCHThree               CFThree              L-47a
H C (CHThree)2CH2SCHThree               CFThree              L-47d
H C (CHThree)2CH2SCHThree               CFThree             (L-48b) Br
H C (CHThree)2CH2SCHThree               CFThree             (L-50b) Cl
H C (CHThree)2CH2SCHThree               CFThree             (L-50b) Br
H C (CHThree)2CH2SCHThree               CFThree             (L-51b) Cl
H C (CHThree)2CH2SCHThree               CF2Cl Ph-4-Cl
H C (CHThree)2CH2SCHThree               CF2Cl Ph-4-Br
H C (CHThree)2CH2SCHThree               CF2Cl Ph-4-CFThree
H C (CHThree)2CH2SCHThree               CF2Cl Ph-4-OCFThree
H C (CHThree)2CH2SCHThree               CF2Cl Ph-4-OCF2Br
H C (CHThree)2CH2SCHThree               CF2Cl Ph-4-OCF2CHFCFThree
H C (CHThree)2CH2SCHThree               CF2Cl Ph-4-OCF2CHFOCFThree
H C (CHThree)2CH2SCHThree               CF2Cl Ph-4-OCF2CHFOCF2CF2CFThree
H C (CHThree)2CH2SCHThree               CF2Cl Ph-4-O (L-45g)
H C (CHThree)2CH2SCHThree               CF2Cl Ph-3,4-Cl2
H C (CHThree)2CH2SCHThree               CF2Cl Ph (-3-OCF2O-4-)
H C (CHThree)2CH2SCHThree               CF2Cl Ph (-3-OCF2CF2O-4-)
H C (CHThree)2CH2SCHThree               CF2Cl (L-45c) CFThree
H C (CHThree)2CH2SCHThree               CF2Cl L-45f
H C (CHThree)2CH2SCHThree               CF2Cl (L-46c) CFThree
H C (CHThree)2CH2SCHThree               CF2Cl L-46d
H C (CHThree)2CH2SCHThree               CFCl2            Ph-4-OCFThree
H C (CHThree)2CH2SCHThree               CF2Br Ph-4-Cl
H C (CHThree)2CH2SCHThree               CF2Br Ph-4-Br
H C (CHThree)2CH2SCHThree               CF2Br Ph-4-CFThree
H C (CHThree)2CH2SCHThree               CF2Br Ph-4-OCFThree
H C (CHThree)2CH2SCHThree               CF2Br Ph-4-OCF2Br
H C (CHThree)2CH2SCHThree               CF2Br Ph-4-OCF2CHFCFThree
H C (CHThree)2CH2SCHThree               CF2Br Ph-4-OCF2CHFOCFThree
H C (CHThree)2CH2SCHThree               CF2Br Ph-4-OCF2CHFOCF2CF2CFThree
H C (CHThree)2CH2SCHThree               CF2Br Ph-4-O (L-45g)
H C (CHThree)2CH2SCHThree               CF2Br Ph-3,4-Cl2
H C (CHThree)2CH2SCHThree               CF2Br Ph (-3-OCF2O-4-)
H C (CHThree)2CH2SCHThree               CF2Br Ph (-3-OCF2CF2O-4-)
H C (CHThree)2CH2SCHThree               CF2Br (L-45c) CFThree
H C (CHThree)2CH2SCHThree               CF2Br L-45f
H C (CHThree)2CH2SCHThree               CF2Br (L-46c) CFThree
H C (CHThree)2CH2SCHThree               CF2Br L-46d
H C (CHThree)2CH2SCHThree               CFClBr (L-45c) CFThree
H C (CHThree)2CH2SCHThree               CFBr2            Ph-4-Br
H C (CHThree)2CH2SCHThree               CF2CHF2          Ph-4-CFThree
H C (CHThree)2CH2SCHThree               CF2CFThree           Ph-4-Cl
H C (CHThree)2CH2SCHThree               CF2CFThree           Ph-4-Br
H C (CHThree)2CH2SCHThree               CF2CFThree           Ph-4-CFThree
H C (CHThree)2CH2SCHThree               CF2CFThree           Ph-4-OCFThree
H C (CHThree)2CH2SCHThree               CF2CFThree           Ph-4-OCF2Br
H C (CHThree)2CH2SCHThree               CF2CFThree           Ph-4-OCF2CHFCFThree
H C (CHThree)2CH2SCHThree               CF2CFThree           Ph-4-OCF2CHFOCFThree
H C (CHThree)2CH2SCHThree               CF2CFThree           Ph-4-OCF2CHFOCF2CF2CFThree
H C (CHThree)2CH2SCHThree               CF2CFThree           Ph-4-O (L-45g)
H C (CHThree)2CH2SCHThree               CF2CFThree           Ph-3,4-Cl2
H C (CHThree)2CH2SCHThree               CF2CFThree           Ph (-3-OCF2O-4-)
H C (CHThree)2CH2SCHThree               CF2CFThree           Ph (-3-OCF2CF2O-4-)
H C (CHThree)2CH2SCHThree               CF2CFThree          (L-45c) CFThree
H C (CHThree)2CH2SCHThree               CF2CFThree           L-45f
H C (CHThree)2CH2SCHThree               CF2CFThree          (L-46c) CFThree
H C (CHThree)2CH2SCHThree               CF2CFThree           L-46d
H C (CHThree)2CH2SCHThree               CF2CF2Cl Ph-4-OCFThree
H C (CHThree)2CH2SCHThree               CFClCFThree         (L-45c) CFThree
H C (CHThree)2CH2SCHThree               CFClCF2Cl Ph-4-Br
H C (CHThree)2CH2SCHThree               CF2CF2Br Ph-4-CFThree
H C (CHThree)2CH2SCHThree               CFBrCFThree          Ph-4-OCFThree
H C (CHThree)2CH2SCHThree               CF2CHFCFThree       (L-45c) CFThree
H C (CHThree)2CH2SCHThree               CF2CF2CFThree        Ph-4-Cl
H C (CHThree)2CH2SCHThree               CF2CF2CFThree        Ph-4-Br
H C (CHThree)2CH2SCHThree               CF2CF2CFThree        Ph-4-CFThree
H C (CHThree)2CH2SCHThree               CF2CF2CFThree        Ph-4-OCFThree
H C (CHThree)2CH2SCHThree               CF2CF2CFThree        Ph-4-OCF2Br
H C (CHThree)2CH2SCHThree               CF2CF2CFThree        Ph-4-OCF2CHFCFThree
H C (CHThree)2CH2SCHThree               CF2CF2CFThree        Ph-4-OCF2CHFOCFThree
H C (CHThree)2CH2SCHThree               CF2CF2CFThree        Ph-4-OCF2CHFOCF2CF2CFThree
H C (CHThree)2CH2SCHThree               CF2CF2CFThree        Ph-4-O (L-45g)
H C (CHThree)2CH2SCHThree               CF2CF2CFThree        Ph-3,4-Cl2
H C (CHThree)2CH2SCHThree               CF2CF2CFThree        Ph (-3-OCF2O-4-)
H C (CHThree)2CH2SCHThree               CF2CF2CFThree        Ph (-3-OCF2CF2O-4-)
H C (CHThree)2CH2SCHThree               CF2CF2CFThree       (L-45c) CFThree
H C (CHThree)2CH2SCHThree               CF2CF2CFThree        L-45f
H C (CHThree)2CH2SCHThree               CF2CF2CFThree       (L-46c) CFThree
H C (CHThree)2CH2SCHThree               CF2CF2CFThree        L-46d
H C (CHThree)2CH2SCHThree               CF (CFThree)2         Ph-4-Br
H C (CHThree)2CH2SCHThree               CF2CF2CF2CFThree     Ph-4-CFThree
H C (CHThree)2CH2SCHThree               T-1 Ph-4-OCFThree
H C (CHThree)2CH2SCHThree               T-2 (L-45c) CFThree
H C (CHThree)2CH2SCHThree               CH2OCHThree          Ph-4-Br
H C (CHThree)2CH2SCHThree               CH2OEt Ph-4-CFThree
H C (CHThree)2CH2SCHThree               CH2OCH2CFThree       Ph-4-OCFThree
H C (CHThree)2CH2SCHThree               CH2OCH (CFThree)2    (L-45c) CFThree
H C (CHThree)2CH2SCHThree               CF2OCHThree          Ph-4-Cl
H C (CHThree)2CH2SCHThree               CF2OCHThree          Ph-4-Br
H C (CHThree)2CH2SCHThree               CF2OCHThree          Ph-4-CFThree
H C (CHThree)2CH2SCHThree               CF2OCHThree          Ph-4-OCFThree
H C (CHThree)2CH2SCHThree               CF2OCHThree          Ph-4-OCF2Br
H C (CHThree)2CH2SCHThree               CF2OCHThree          Ph-4-OCF2CHFCFThree
H C (CHThree)2CH2SCHThree               CF2OCHThree          Ph-4-OCF2CHFOCFThree
H C (CHThree)2CH2SCHThree               CF2OCHThree          Ph-4-OCF2CHFOCF2CF2CFThree
H C (CHThree)2CH2SCHThree               CF2OCHThree          Ph-4-O (L-45g)
H C (CHThree)2CH2SCHThree               CF2OCHThree          Ph-3,4-Cl2
H C (CHThree)2CH2SCHThree               CF2OCHThree          Ph (-3-OCF2O-4-)
H C (CHThree)2CH2SCHThree               CF2OCHThree          Ph (-3-OCF2CF2O-4-)
H C (CHThree)2CH2SCHThree               CF2OCHThree         (L-45c) CFThree
H C (CHThree)2CH2SCHThree               CF2OCHThree          L-45f
H C (CHThree)2CH2SCHThree               CF2OCHThree         (L-46c) CFThree
H C (CHThree)2CH2SCHThree               CF2OCHThree          L-46d
H C (CHThree)2CH2SCHThree               CH2SCHThree          Ph-4-Br
H C (CHThree)2CH2SCHThree               CH2SO2CHThree        Ph-4-CFThree
H C (CHThree)2CH2SCHThree               CH2SCFThree          Ph-4-OCFThree
H C (CHThree)2CH2SCHThree               CF2SCHThree          Ph-4-Cl
H C (CHThree)2CH2SCHThree               CF2SCHThree          Ph-4-Br
H C (CHThree)2CH2SCHThree               CF2SCHThree          Ph-4-CFThree
H C (CHThree)2CH2SCHThree               CF2SCHThree          Ph-4-OCFThree
H C (CHThree)2CH2SCHThree               CF2SCHThree          Ph-4-OCF2Br
H C (CHThree)2CH2SCHThree               CF2SCHThree          Ph-4-OCF2CHFCFThree
H C (CHThree)2CH2SCHThree               CF2SCHThree          Ph-4-OCF2CHFOCFThree
H C (CHThree)2CH2SCHThree               CF2SCHThree          Ph-4-OCF2CHFOCF2CF2CFThree
H C (CHThree)2CH2SCHThree               CF2SCHThree          Ph-4-O (L-45g)
H C (CHThree)2CH2SCHThree               CF2SCHThree          Ph-3,4-Cl2
H C (CHThree)2CH2SCHThree               CF2SCHThree          Ph (-3-OCF2O-4-)
H C (CHThree)2CH2SCHThree               CF2SCHThree          Ph (-3-OCF2CF2O-4-)
H C (CHThree)2CH2SCHThree               CF2SCHThree         (L-45c) CFThree
H C (CHThree)2CH2SCHThree               CF2SCHThree          L-45f
H C (CHThree)2CH2SCHThree               CF2SCHThree         (L-46c) CFThree
H C (CHThree)2CH2SCHThree               CF2SCHThree          L-46d
H C (CHThree)2CH2SCHThree               CF2SEt (L-45c) CFThree
H C (CHThree)2CH2SCHThree               CF2SPr-n Ph-4-Br
H C (CHThree)2CH2SCHThree               CF2SPr-i Ph-4-CFThree 
H C (CHThree)2CH2SCHThree               CF2SCH2Ph Ph-4-OCFThree
H C (CHThree)2CH2SCHThree               CF2SPh (L-45c) CFThree
H C (CHThree)2CH2SCHThree               CF2C (O) OEt Ph-4-Br
H C (CHThree)2CH2SCHThree               CF2SO2N (CHThree)2    Ph-4-CFThree 
H C (CHThree)2CH2SCHThree               C (O) OEt Ph-4-OCFThree
H C (CHThree)2CH2SCHThree               C (O) SEt (L-45c) CFThree
H C (CHThree)2CH2S (O) CHThree            CHThree              Ph-4-Br
H C (CHThree)2CH2S (O) CHThree            CHThree              Ph-4-CFThree
H C (CHThree)2CH2S (O) CHThree            CHThree              Ph-4-OCFThree
H C (CHThree)2CH2S (O) CHThree            CHThree             (L-45c) CFThree
H C (CHThree)2CH2S (O) CHThree            CFThree              CH2O (Ph-4-Cl)
H C (CHThree)2CH2S (O) CHThree            CFThree              CH2O (Ph-4-Br)
H C (CHThree)2CH2S (O) CHThree            CFThree              CH2O (Ph-4-CFThree)
H C (CHThree)2CH2S (O) CHThree            CFThree              CH2O (Ph-4-OCFThree)
H C (CHThree)2CH2S (O) CHThree            CFThree              CF2O (Ph-4-Cl)
H C (CHThree)2CH2S (O) CHThree            CFThree              CF2O (Ph-4-Br)
H C (CHThree)2CH2S (O) CHThree            CFThree              CF2O (Ph-4-CFThree)
H C (CHThree)2CH2S (O) CHThree            CFThree              CF2O (Ph-4-OCFThree)
H C (CHThree)2CH2S (O) CHThree            CFThree              CH = CH (Ph-4-F)
H C (CHThree)2CH2S (O) CHThree            CFThree              CH = CH (Ph-4-Cl)
H C (CHThree)2CH2S (O) CHThree            CFThree              CH = CH (Ph-4-Br)
H C (CHThree)2CH2S (O) CHThree            CFThree              CH = CH (Ph-4-CFThree)
H C (CHThree)2CH2S (O) CHThree            CFThree              CH = CH (Ph-4-OCFThree)
H C (CHThree)2CH2S (O) CHThree            CFThree              CH = CH (Ph-4-SCHThree)
H C (CHThree)2CH2S (O) CHThree            CFThree              CH = CH (Ph-4-SO2CHThree)
H C (CHThree)2CH2S (O) CHThree            CFThree              CH = CH (Ph-3,4-Cl2)
H C (CHThree)2CH2S (O) CHThree            CFThree              Ph-4-F
H C (CHThree)2CH2S (O) CHThree            CFThree              Ph-2-Cl
H C (CHThree)2CH2S (O) CHThree            CFThree              Ph-3-Cl
H C (CHThree)2CH2S (O) CHThree            CFThree              Ph-4-Cl
H C (CHThree)2CH2S (O) CHThree            CFThree              Ph-4-Br
H C (CHThree)2CH2S (O) CHThree            CFThree              Ph-4-I
H C (CHThree)2CH2S (O) CHThree            CFThree              Ph-4-CFThree
H C (CHThree)2CH2S (O) CHThree            CFThree              Ph-4-OCHF2
H C (CHThree)2CH2S (O) CHThree            CFThree              Ph-4-OCFThree
H C (CHThree)2CH2S (O) CHThree(-) CFThree              Ph-4-OCFThree
H C (CHThree)2CH2S (O) CHThree(+) CFThree              Ph-4-OCFThree
H C (CHThree)2CH2S (O) CHThree            CFThree              Ph-4-OCF2Br
H C (CHThree)2CH2S (O) CHThree            CFThree              Ph-4-OCH2CFThree
H C (CHThree)2CH2S (O) CHThree            CFThree              Ph-4-OCF2CHF2
H C (CHThree)2CH2S (O) CHThree            CFThree              Ph-4-OCF2CHFCl
H C (CHThree)2CH2S (O) CHThree            CFThree              Ph-4-OCF2CHFCFThree
H C (CHThree)2CH2S (O) CHThree            CFThree              Ph-4-OCF2CHFOCFThree
H C (CHThree)2CH2S (O) CHThree            CFThree              Ph-4-OCF2CHFOCF2CF2CFThree
H C (CHThree)2CH2S (O) CHThree            CFThree              Ph-4-OSO2CHThree
H C (CHThree)2CH2S (O) CHThree            CFThree              Ph-4-OSO2CFThree
H C (CHThree)2CH2S (O) CHThree            CFThree              Ph-4-O (L-45e)
H C (CHThree)2CH2S (O) CHThree            CFThree              Ph-2,4-F2
H C (CHThree)2CH2S (O) CHThree            CFThree              Ph-3,4-F2
H C (CHThree)2CH2S (O) CHThree            CFThree              Ph-3-Cl-4-F
H C (CHThree)2CH2S (O) CHThree            CFThree              Ph-2-F-4-Cl
H C (CHThree)2CH2S (O) CHThree            CFThree              Ph-3-F-4-Cl
H C (CHThree)2CH2S (O) CHThree            CFThree              Ph-2,4-Cl2
H C (CHThree)2CH2S (O) CHThree            CFThree              Ph-3,4-Cl2
H C (CHThree)2CH2S (O) CHThree            CFThree              Ph-3,5-Cl2
H C (CHThree)2CH2S (O) CHThree            CFThree              Ph-3-Br-4-F
H C (CHThree)2CH2S (O) CHThree            CFThree              Ph-2-F-4-Br
H C (CHThree)2CH2S (O) CHThree            CFThree              Ph-3,4-Br2
H C (CHThree)2CH2S (O) CHThree            CFThree              Ph-3-CHThree-4-F
H C (CHThree)2CH2S (O) CHThree            CFThree              Ph-3-CFThree-4-F
H C (CHThree)2CH2S (O) CHThree            CFThree              Ph-3-CFThree-4-Cl
H C (CHThree)2CH2S (O) CHThree            CFThree              Ph-2-F-4-CFThree
H C (CHThree)2CH2S (O) CHThree            CFThree              Ph-3-F-4-CFThree
H C (CHThree)2CH2S (O) CHThree            CFThree              Ph-2-Cl-4-CFThree
H C (CHThree)2CH2S (O) CHThree            CFThree              Ph-3-F-4-OCHF2
H C (CHThree)2CH2S (O) CHThree            CFThree              Ph-3-Cl-4-OCHF2
H C (CHThree)2CH2S (O) CHThree            CFThree              Ph-3-Br-4-OCHF2
H C (CHThree)2CH2S (O) CHThree            CFThree              Ph-3-F-4-OCFThree
H C (CHThree)2CH2S (O) CHThree            CFThree              Ph-3-Cl-4-OCFThree
H C (CHThree)2CH2S (O) CHThree            CFThree              Ph-3-Br-4-OCFThree
H C (CHThree)2CH2S (O) CHThree            CFThree              Ph-3-F-4-OCF2Br
H C (CHThree)2CH2S (O) CHThree            CFThree              Ph-3-Cl-4-OCF2Br
H C (CHThree)2CH2S (O) CHThree            CFThree              Ph-3-Br-4-OCF2Br
H C (CHThree)2CH2S (O) CHThree            CFThree              Ph-3-F-4-OCF2CHF2
H C (CHThree)2CH2S (O) CHThree            CFThree              Ph-3-Cl-4-OCF2CHF2
H C (CHThree)2CH2S (O) CHThree            CFThree              Ph-3-Br-4-OCF2CHF2
H C (CHThree)2CH2S (O) CHThree            CFThree              Ph-3-F-4-OCF2CHFCl
H C (CHThree)2CH2S (O) CHThree            CFThree              Ph-3-Cl-4-OCF2CHFCl
H C (CHThree)2CH2S (O) CHThree            CFThree              Ph-3-Br-4-OCF2CHFCl
H C (CHThree)2CH2S (O) CHThree            CFThree              Ph-3-F-4-OCF2CHFCFThree
H C (CHThree)2CH2S (O) CHThree            CFThree              Ph-3-Cl-4-OCF2CHFCFThree
H C (CHThree)2CH2S (O) CHThree            CFThree              Ph-3-Br-4-OCF2CHFCFThree
H C (CHThree)2CH2S (O) CHThree            CFThree              Ph-3-F-4-OCF2CHFOCFThree
H C (CHThree)2CH2S (O) CHThree            CFThree              Ph-3-Cl-4-OCF2CHFOCFThree
H C (CHThree)2CH2S (O) CHThree            CFThree              Ph-3-Br-4-OCF2CHFOCFThree
H C (CHThree)2CH2S (O) CHThree            CFThree              Ph-3-CHThree-4-OCF2CHFOCFThree
H C (CHThree)2CH2S (O) CHThree            CFThree         Ph-3-F-4-OCF2CHFOCF2CF2CFThree
H C (CHThree)2CH2S (O) CHThree            CFThree         Ph-3-Cl-4-OCF2CHFOCF2CF2CFThree
H C (CHThree)2CH2S (O) CHThree            CFThree         Ph-3-Br-4-OCF2CHFOCF2CF2CFThree
H C (CHThree)2CH2S (O) CHThree            CFThree              Ph (-3-OCF2O-4-)
H C (CHThree)2CH2S (O) CHThree            CFThree              Ph (-3-OCF2CF2O-4-)
H C (CHThree)2CH2S (O) CHThree            CFThree              Ph-3,4-F2-5-CFThree
H C (CHThree)2CH2S (O) CHThree            CFThree              2-Naph
H C (CHThree)2CH2S (O) CHThree            CFThree             (L-1b) Br
H C (CHThree)2CH2S (O) CHThree            CFThree             (L-1c) Cl
H C (CHThree)2CH2S (O) CHThree            CFThree             (L-1c) Br
H C (CHThree)2CH2S (O) CHThree            CFThree             (L-1c) CFThree
H C (CHThree)2CH2S (O) CHThree            CFThree             (L-2b) Br
H C (CHThree)2CH2S (O) CHThree            CFThree             (L-3b) Cl
H C (CHThree)2CH2S (O) CHThree            CFThree             (L-3b) Br
H C (CHThree)2CH2S (O) CHThree            CFThree             (L-3c) Cl
H C (CHThree)2CH2S (O) CHThree            CFThree             (L-3c) Br
H C (CHThree)2CH2S (O) CHThree            CFThree             (L-3c) CFThree
H C (CHThree)2CH2S (O) CHThree            CFThree              L-3d
H C (CHThree)2CH2S (O) CHThree            CFThree             (L-4b) Cl
H C (CHThree)2CH2S (O) CHThree            CFThree             (L-4b) Br
H C (CHThree)2CH2S (O) CHThree            CFThree             (L-10b) Cl
H C (CHThree)2CH2S (O) CHThree            CFThree             (L-10b) Br
H C (CHThree)2CH2S (O) CHThree            CFThree             (L-15b) CFThree
H C (CHThree)2CH2S (O) CHThree            CFThree             (L-16a) CHF2
H C (CHThree)2CH2S (O) CHThree            CFThree             (L-16a) CF2Br
H C (CHThree)2CH2S (O) CHThree            CFThree             (L-17a) Cl
H C (CHThree)2CH2S (O) CHThree            CFThree             (L-21b) Cl
H C (CHThree)2CH2S (O) CHThree            CFThree             (L-21b) Br
H C (CHThree)2CH2S (O) CHThree            CFThree             (L-21b) CFThree
H C (CHThree)2CH2S (O) CHThree            CFThree             (L-22b) Cl
H C (CHThree)2CH2S (O) CHThree            CFThree             (L-22b) Br
H C (CHThree)2CH2S (O) CHThree            CFThree             (L-23b) Cl
H C (CHThree)2CH2S (O) CHThree            CFThree             (L-23b) Br
H C (CHThree)2CH2S (O) CHThree            CFThree             (L-23c) Cl
H C (CHThree)2CH2S (O) CHThree            CFThree             (L-23c) Br
H C (CHThree)2CH2S (O) CHThree            CFThree             (L-31a) Cl
H C (CHThree)2CH2S (O) CHThree            CFThree             (L-31a) Br
H C (CHThree)2CH2S (O) CHThree            CFThree             (L-45c) F
H C (CHThree)2CH2S (O) CHThree            CFThree             (L-45c) Cl
H C (CHThree)2CH2S (O) CHThree            CFThree             (L-45c) Br
H C (CHThree)2CH2S (O) CHThree            CFThree             (L-45c) CFThree
H C (CHThree)2CH2S (O) CHThree            CFThree              L-45e
H C (CHThree)2CH2S (O) CHThree            CFThree              L-45f
H C (CHThree)2CH2S (O) CHThree            CFThree             (L-46c) F
H C (CHThree)2CH2S (O) CHThree            CFThree             (L-46c) Cl
H C (CHThree)2CH2S (O) CHThree            CFThree             (L-46c) Br
H C (CHThree)2CH2S (O) CHThree            CFThree             (L-46c) CFThree
H C (CHThree)2CH2S (O) CHThree            CFThree              L-46d
H C (CHThree)2CH2S (O) CHThree            CFThree              L-47a
H C (CHThree)2CH2S (O) CHThree            CFThree              L-47d
H C (CHThree)2CH2S (O) CHThree            CFThree             (L-48b) Br
H C (CHThree)2CH2S (O) CHThree            CFThree             (L-50b) Cl
H C (CHThree)2CH2S (O) CHThree            CFThree             (L-50b) Br
H C (CHThree)2CH2S (O) CHThree            CFThree             (L-51b) Cl
H C (CHThree)2CH2SO2CHThree             CHThree              CF2O (Ph-4-Cl)
H C (CHThree)2CH2SO2CHThree             CHThree              CH = CH (Ph-4-Cl)
H C (CHThree)2CH2SO2CHThree             CHThree              CH = CH (Ph-4-OCFThree)
H C (CHThree)2CH2SO2CHThree             CHThree              CH = CH (Ph-3,4-Cl2)
H C (CHThree)2CH2SO2CHThree             CHThree              Ph-4-F
H C (CHThree)2CH2SO2CHThree             CHThree              Ph-4-Cl
H C (CHThree)2CH2SO2CHThree             CHThree              Ph-4-Br
H C (CHThree)2CH2SO2CHThree             CHThree              Ph-4-I
H C (CHThree)2CH2SO2CHThree             CHThree              Ph-4-CFThree
H C (CHThree)2CH2SO2CHThree             CHThree              Ph-4-OCHF2
H C (CHThree)2CH2SO2CHThree             CHThree              Ph-4-OCFThree
H C (CHThree)2CH2SO2CHThree             CHThree              Ph-4-OCF2Br
H C (CHThree)2CH2SO2CHThree             CHThree              Ph-4-OCF2CHF2
H C (CHThree)2CH2SO2CHThree             CHThree              Ph-4-OCF2CHFCl
H C (CHThree)2CH2SO2CHThree             CHThree              Ph-4-OCF2CHFCFThree
H C (CHThree)2CH2SO2CHThree             CHThree              Ph-4-OCF2CHFOCFThree
H C (CHThree)2CH2SO2CHThree             CHThree              Ph-4-OCF2CHFOCF2CF2CFThree
H C (CHThree)2CH2SO2CHThree             CHThree              Ph-4-O (L-45g)
H C (CHThree)2CH2SO2CHThree             CHThree              Ph-3,4-Cl2
H C (CHThree)2CH2SO2CHThree             CHThree              Ph (-3-OCF2O-4-)
H C (CHThree)2CH2SO2CHThree             CHThree              Ph (-3-OCF2CF2O-4-)
H C (CHThree)2CH2SO2CHThree             CHThree             (L-45c) Cl
H C (CHThree)2CH2SO2CHThree             CHThree             (L-45c) Br
H C (CHThree)2CH2SO2CHThree             CHThree             (L-45c) CFThree
H C (CHThree)2CH2SO2CHThree             CHThree              L-45e
H C (CHThree)2CH2SO2CHThree             CHThree              L-45f
H C (CHThree)2CH2SO2CHThree             CHThree             (L-46c) Cl
H C (CHThree)2CH2SO2CHThree             CHThree             (L-46c) Br
H C (CHThree)2CH2SO2CHThree             CHThree             (L-46c) CFThree
H C (CHThree)2CH2SO2CHThree             CHThree              L-46d
H C (CHThree)2CH2SO2CHThree             Et Ph-4-Cl
H C (CHThree)2CH2SO2CHThree             Et Ph-4-Br
H C (CHThree)2CH2SO2CHThree             Et Ph-4-CFThree
H C (CHThree)2CH2SO2CHThree             Et Ph-4-OCFThree
H C (CHThree)2CH2SO2CHThree             Et Ph-4-OCF2Br
H C (CHThree)2CH2SO2CHThree             Et Ph-4-OCF2CHFCFThree
H C (CHThree)2CH2SO2CHThree             Et Ph-4-OCF2CHFOCFThree
H C (CHThree)2CH2SO2CHThree             Et Ph-4-OCF2CHFOCF2CF2CFThree
H C (CHThree)2CH2SO2CHThree             Et Ph-4-O (L-45g)
H C (CHThree)2CH2SO2CHThree             Et Ph-3,4-Cl2
H C (CHThree)2CH2SO2CHThree             Et Ph (-3-OCF2O-4-)
H C (CHThree)2CH2SO2CHThree             Et Ph (-3-OCF2CF2O-4-)
H C (CHThree)2CH2SO2CHThree             Et (L-45c) CFThree
H C (CHThree)2CH2SO2CHThree             n-Pr Ph-4-Br
H C (CHThree)2CH2SO2CHThree             n-Pr Ph-4-CFThree
H C (CHThree)2CH2SO2CHThree             n-Pr Ph-4-OCFThree
H C (CHThree)2CH2SO2CHThree             n-Pr (L-45c) CFThree
H C (CHThree)2CH2SO2CHThree             i-Pr Ph-4-Br
H C (CHThree)2CH2SO2CHThree             i-Pr Ph-4-CFThree
H C (CHThree)2CH2SO2CHThree             i-Pr Ph-4-OCFThree
H C (CHThree)2CH2SO2CHThree             i-Pr (L-45c) CFThree
H C (CHThree)2CH2SO2CHThree             c-Pr Ph-4-Br
H C (CHThree)2CH2SO2CHThree             c-Pr Ph-4-CFThree
H C (CHThree)2CH2SO2CHThree             c-Pr Ph-4-OCFThree
H C (CHThree)2CH2SO2CHThree             c-Pr (L-45c) CFThree
H C (CHThree)2CH2SO2CHThree             n-Bu Ph-4-OCFThree
H C (CHThree)2CH2SO2CHThree             CH2F (L-45c) CFThree
H C (CHThree)2CH2SO2CHThree             CH2Cl Ph-4-Br
H C (CHThree)2CH2SO2CHThree             CH2Br Ph-4-CFThree
H C (CHThree)2CH2SO2CHThree             CHF2             Ph-4-Cl
H C (CHThree)2CH2SO2CHThree             CHF2             Ph-4-Br
H C (CHThree)2CH2SO2CHThree             CHF2             Ph-4-CFThree
H C (CHThree)2CH2SO2CHThree             CHF2             Ph-4-OCFThree
H C (CHThree)2CH2SO2CHThree             CHF2             Ph-4-OCF2Br
H C (CHThree)2CH2SO2CHThree             CHF2             Ph-4-OCF2CHFCFThree
H C (CHThree)2CH2SO2CHThree             CHF2             Ph-4-OCF2CHFOCFThree
H C (CHThree)2CH2SO2CHThree             CHF2             Ph-4-OCF2CHFOCF2CF2CFThree
H C (CHThree)2CH2SO2CHThree             CHF2             Ph-4-O (L-45g)
H C (CHThree)2CH2SO2CHThree             CHF2             Ph-3,4-Cl2
H C (CHThree)2CH2SO2CHThree             CHF2             Ph (-3-OCF2O-4-)
H C (CHThree)2CH2SO2CHThree             CHF2             Ph (-3-OCF2CF2O-4-)
H C (CHThree)2CH2SO2CHThree             CHF2            (L-45c) CFThree
H C (CHThree)2CH2SO2CHThree             CHF2             L-45f
H C (CHThree)2CH2SO2CHThree             CHF2            (L-46c) CFThree
H C (CHThree)2CH2SO2CHThree             CHF2             L-46d
H C (CHThree)2CH2SO2CHThree             CHFCl Ph-4-OCFThree
H C (CHThree)2CH2SO2CHThree             CHFBr (L-45c) CFThree
H C (CHThree)2CH2SO2CHThree             CFThree              c-Pr
H C (CHThree)2CH2SO2CHThree             CFThree              c-Bu
H C (CHThree)2CH2SO2CHThree             CFThree              c-Pen
H C (CHThree)2CH2SO2CHThree             CFThree              c-Hex
H C (CHThree)2CH2SO2CHThree             CFThree              T-1
H C (CHThree)2CH2SO2CHThree             CFThree              T-2
H C (CHThree)2CH2SO2CHThree             CFThree              T-3
H C (CHThree)2CH2SO2CHThree             CFThree              T-4
H C (CHThree)2CH2SO2CHThree             CFThree              T-5
H C (CHThree)2CH2SO2CHThree             CFThree              CH2OCHThree
H C (CHThree)2CH2SO2CHThree             CFThree              CH2OEt
H C (CHThree)2CH2SO2CHThree             CFThree              CH2OPr-n
H C (CHThree)2CH2SO2CHThree             CFThree              CH2OPr-i
H C (CHThree)2CH2SO2CHThree             CFThree              CH2OBu-n
H C (CHThree)2CH2SO2CHThree             CFThree              CH2OC (O) (Ph-2-Cl)
H C (CHThree)2CH2SO2CHThree             CFThree              CH2OC (O) (Ph-3-Cl)
H C (CHThree)2CH2SO2CHThree             CFThree              CH2OC (O) (Ph-4-Cl)
H C (CHThree)2CH2SO2CHThree             CFThree              CH2OPh
H C (CHThree)2CH2SO2CHThree             CFThree              CH2O (Ph-2-F)
H C (CHThree)2CH2SO2CHThree             CFThree              CH2O (Ph-3-F)
H C (CHThree)2CH2SO2CHThree             CFThree              CH2O (Ph-4-F)
H C (CHThree)2CH2SO2CHThree             CFThree              CH2O (Ph-2-Cl)
H C (CHThree)2CH2SO2CHThree             CFThree              CH2O (Ph-3-Cl)
H C (CHThree)2CH2SO2CHThree             CFThree              CH2O (Ph-4-Cl)
H C (CHThree)2CH2SO2CHThree             CFThree              CH2O (Ph-2-Br)
H C (CHThree)2CH2SO2CHThree             CFThree              CH2O (Ph-3-Br)
H C (CHThree)2CH2SO2CHThree             CFThree              CH2O (Ph-4-Br)
H C (CHThree)2CH2SO2CHThree             CFThree              CH2O (Ph-2-CFThree)
H C (CHThree)2CH2SO2CHThree             CFThree              CH2O (Ph-3-CFThree)
H C (CHThree)2CH2SO2CHThree             CFThree              CH2O (Ph-4-CFThree)
H C (CHThree)2CH2SO2CHThree             CFThree              CH2O (Ph-2-OCFThree)
H C (CHThree)2CH2SO2CHThree             CFThree              CH2O (Ph-3-OCFThree)
H C (CHThree)2CH2SO2CHThree             CFThree              CH2O (Ph-4-OCFThree)
H C (CHThree)2CH2SO2CHThree             CFThree              CF2OPh
H C (CHThree)2CH2SO2CHThree             CFThree              CF2O (Ph-2-F)
H C (CHThree)2CH2SO2CHThree             CFThree              CF2O (Ph-3-F)
H C (CHThree)2CH2SO2CHThree             CFThree              CF2O (Ph-4-F)
H C (CHThree)2CH2SO2CHThree             CFThree              CF2O (Ph-2-Cl)
H C (CHThree)2CH2SO2CHThree             CFThree              CF2O (Ph-3-Cl)
H C (CHThree)2CH2SO2CHThree             CFThree              CF2O (Ph-4-Cl)
H C (CHThree)2CH2SO2CHThree             CFThree              CF2O (Ph-2-Br)
H C (CHThree)2CH2SO2CHThree             CFThree              CF2O (Ph-3-Br)
H C (CHThree)2CH2SO2CHThree             CFThree              CF2O (Ph-4-Br)
H C (CHThree)2CH2SO2CHThree             CFThree              CF2O (Ph-2-CFThree)
H C (CHThree)2CH2SO2CHThree             CFThree              CF2O (Ph-3-CFThree)
H C (CHThree)2CH2SO2CHThree             CFThree              CF2O (Ph-4-CFThree)
H C (CHThree)2CH2SO2CHThree             CFThree              CF2O (Ph-2-OCFThree)
H C (CHThree)2CH2SO2CHThree             CFThree              CF2O (Ph-3-OCFThree)
H C (CHThree)2CH2SO2CHThree             CFThree              CF2O (Ph-4-OCFThree)
H C (CHThree)2CH2SO2CHThree             CFThree              CH2S (Ph-2-Cl)
H C (CHThree)2CH2SO2CHThree             CFThree              CH2S (Ph-3-Cl)
H C (CHThree)2CH2SO2CHThree             CFThree              CH2S (Ph-4-Cl)
H C (CHThree)2CH2SO2CHThree             CFThree              CH2SO2(Ph-2-Cl)
H C (CHThree)2CH2SO2CHThree             CFThree              CH2SO2(Ph-3-Cl)
H C (CHThree)2CH2SO2CHThree             CFThree              CH2SO2(Ph-4-Cl)
H C (CHThree)2CH2SO2CHThree             CFThree              CH2N (CHThree)2
H C (CHThree)2CH2SO2CHThree             CFThree              CH2NH (Ph-2-Cl)
H C (CHThree)2CH2SO2CHThree             CFThree              CH2NH (Ph-3-Cl)
H C (CHThree)2CH2SO2CHThree             CFThree              CH2NH (Ph-4-Cl)
H C (CHThree)2CH2SO2CHThree             CFThree              CF2C (O) OEt
H C (CHThree)2CH2SO2CHThree             CFThree              CH2(L-5a)
H C (CHThree)2CH2SO2CHThree             CFThree              CH2(L-14a)
H C (CHThree)2CH2SO2CHThree             CFThree              CH2(L-24a)
H C (CHThree)2CH2SO2CHThree             CFThree              CH2(L-36a)
H C (CHThree)2CH2SO2CHThree             CFThree              CH2CH2Ph
H C (CHThree)2CH2SO2CHThree             CFThree              CH2CH2(Ph-2-Cl)
H C (CHThree)2CH2SO2CHThree             CFThree              CH2CH2(Ph-3-Cl)
H C (CHThree)2CH2SO2CHThree             CFThree              CH2CH2(Ph-4-Cl)
H C (CHThree)2CH2SO2CHThree             CFThree              T-22
H C (CHThree)2CH2SO2CHThree             CFThree              T-23
H C (CHThree)2CH2SO2CHThree             CFThree              T-24
H C (CHThree)2CH2SO2CHThree             CFThree              C (O) OEt
H C (CHThree)2CH2SO2CHThree             CFThree              C (O) OBu-t
H C (CHThree)2CH2SO2CHThree             CFThree              C (O) OCH2CFThree
H C (CHThree)2CH2SO2CHThree             CFThree              CH = CH (Ph-2-F)
H C (CHThree)2CH2SO2CHThree             CFThree              CH = CH (Ph-3-F)
H C (CHThree)2CH2SO2CHThree             CFThree              CH = CH (Ph-4-F)
H C (CHThree)2CH2SO2CHThree             CFThree              CH = CH (Ph-2-Cl)
H C (CHThree)2CH2SO2CHThree             CFThree              CH = CH (Ph-3-Cl)
H C (CHThree)2CH2SO2CHThree             CFThree              CH = CH (Ph-4-Cl)
H C (CHThree)2CH2SO2CHThree             CFThree              CH = CH (Ph-2-Br)
H C (CHThree)2CH2SO2CHThree             CFThree              CH = CH (Ph-3-Br)
H C (CHThree)2CH2SO2CHThree             CFThree              CH = CH (Ph-4-Br)
H C (CHThree)2CH2SO2CHThree             CFThree              CH = CH (Ph-2-CFThree)
H C (CHThree)2CH2SO2CHThree             CFThree              CH = CH (Ph-3-CFThree)
H C (CHThree)2CH2SO2CHThree             CFThree              CH = CH (Ph-4-CFThree)
H C (CHThree)2CH2SO2CHThree             CFThree              CH = CH (Ph-2-OCFThree)
H C (CHThree)2CH2SO2CHThree             CFThree              CH = CH (Ph-3-OCFThree)
H C (CHThree)2CH2SO2CHThree             CFThree              CH = CH (Ph-4-OCFThree)
H C (CHThree)2CH2SO2CHThree             CFThree              CH = CH (Ph-2-SCHThree)
H C (CHThree)2CH2SO2CHThree             CFThree              CH = CH (Ph-3-SCHThree)
H C (CHThree)2CH2SO2CHThree             CFThree              CH = CH (Ph-4-SCHThree)
H C (CHThree)2CH2SO2CHThree             CFThree              CH = CH (Ph-2-SO2CHThree)
H C (CHThree)2CH2SO2CHThree             CFThree              CH = CH (Ph-3-SO2CHThree)
H C (CHThree)2CH2SO2CHThree             CFThree              CH = CH (Ph-4-SO2CHThree)
H C (CHThree)2CH2SO2CHThree             CFThree              CH = CH (Ph-3,4-F2)
H C (CHThree)2CH2SO2CHThree             CFThree              CH = CH (Ph-3-F-4-Cl)
H C (CHThree)2CH2SO2CHThree             CFThree              CH = CH (Ph-3,4-Cl2)
H C (CHThree)2CH2SO2CHThree             CFThree              CH = CH (Ph-3,4-Br2)
H C (CHThree)2CH2SO2CHThree             CFThree              CH = CH (Ph-3-F-4-CFThree)
H C (CHThree)2CH2SO2CHThree             CFThree              CH = CH (Ph-3-Cl-4-OCFThree)
H C (CHThree)2CH2SO2CHThree             CFThree              CH = CH [Ph (-3-OCF2O-4-)]
H C (CHThree)2CH2SO2CHThree             CFThree              Ph
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-2-F
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-3-F
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-4-F
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-2-Cl
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-3-Cl
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-4-Cl
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-2-Br
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-3-Br
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-4-Br
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-4-I
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-4-Bu-t
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-2-CFThree
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-3-CFThree
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-4-CFThree
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-4-OCHThree
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-4-OCHF2
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-2-OCFThree
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-3-OCFThree
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-4-OCFThree
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-4-OCF2Br
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-4-OCH2CFThree
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-4-OCF2CHF2
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-4-OCF2CHFCl
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-4-OCF2CHFBr
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-4-OCF2CF2Br
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-4-OCF2CFCl2
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-4-OCF2CClThree
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-4-OCH2CF2CHF2
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-3-OCF2CHFCFThree
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-4-OCF2CHFCFThree
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-4-OCH (CFThree)2
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-4-OCF2CFBrCFThree
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-3-OCF2CHFOCFThree
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-4-OCF2CHFOCFThree
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-4-OCF2CHFOCF2CF2CFThree
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-4-OSO2CHThree
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-4-OSO2CFThree
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-3-O (Ph-4-Cl)
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-4-O (Ph-4-Cl)
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-4-O (Ph-4-Br)
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-4-O (Ph-4-CFThree)
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-4-O (L-45c) Br
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-4-O (L-45c) CFThree
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-3-O (L-45e)
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-4-O (L-45e)
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-4-O (L-48b) Br
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-4-SCHThree
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-4-SO2CHThree
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-3-S (Ph-4-Cl)
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-4-S (Ph-4-Cl)
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-4-S (Ph-4-Br)
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-4-S (Ph-4-CFThree)
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-4-S (L-45c) Br
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-4-S (L-45c) CFThree
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-4-S (L-45e)
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-4-S (L-48b) Br
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-4-NO2
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-4-CN
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-2,3-F2
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-2,4-F2
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-3,4-F2
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-2,5-F2
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-3,5-F2
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-2-Cl-4-F
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-2-F-3-Cl
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-3-Cl-4-F
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-2-F-4-Cl
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-3-F-4-Cl
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-2,3-Cl2
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-2,4-Cl2
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-2,5-Cl2
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-3,4-Cl2
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-3,5-Cl2
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-3-Br-4-F
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-2-F-4-Br
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-2-F-5-Br
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-3,4-Br2
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-3,5-Br2
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-3-CHThree-4-F
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-3-F-4-CHThree
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-2-F-5-CHThree
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-2,4- (CHThree)2
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-3,4- (CHThree)2
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-2-F-3-CFThree
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-3-CFThree-4-F
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-3-CFThree-4-Cl
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-2-F-4-CFThree
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-3-F-4-CFThree
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-2-F-5-CFThree
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-3-F-5-CFThree
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-2-Cl-4-CFThree
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-3,5- (CFThree)2
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-3-Br-4-OCHThree
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-3-F-4-OCHF2
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-3-Cl-4-OCHF2
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-3-Br-4-OCHF2
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-3-F-4-OCFThree
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-3-Cl-4-OCFThree
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-3-Br-4-OCFThree
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-3-F-4-OCF2Br
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-3-Cl-4-OCF2Br
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-3-Br-4-OCF2Br
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-3-F-4-OCF2CHF2
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-3-Cl-4-OCF2CHF2
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-3-Br-4-OCF2CHF2
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-3-F-4-OCF2CHFCl
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-3-Cl-4-OCF2CHFCl
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-3-Br-4-OCF2CHFCl
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-3-F-4-OCF2CHFCFThree
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-3-Cl-4-OCF2CHFCFThree
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-3-Br-4-OCF2CHFCFThree
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-3-F-4-OCF2CHFOCFThree
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-3-Cl-4-OCF2CHFOCFThree
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-3-Br-4-OCF2CHFOCFThree
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-3-CHThree-4-OCF2CHFOCFThree
H C (CHThree)2CH2SO2CHThree             CFThree         Ph-3-F-4-OCF2CHFOCF2CF2CFThree
H C (CHThree)2CH2SO2CHThree             CFThree         Ph-3-Cl-4-OCF2CHFOCF2CF2CFThree
H C (CHThree)2CH2SO2CHThree             CFThree         Ph-3-Br-4-OCF2CHFOCF2CF2CFThree
H C (CHThree)2CH2SO2CHThree             CFThree              Ph (-3-OCF2O-4-)
H C (CHThree)2CH2SO2CHThree             CFThree              Ph (-3-OCF2CF2O-4-)
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-3-OPh-4-F
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-3-NO2-4-F
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-3-NO2-4-Cl
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-2-F-5-NO2
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-3-CN-4-F
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-2,3,4-FThree
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-2,3,5-FThree
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-2,4,5-FThree
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-3,4,5-FThree
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-2,3-F2-4-CHThree
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-2,3-F2-4-CFThree
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-3,4-F2-5-CFThree
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-2-F-3-Cl-5-CFThree
H C (CHThree)2CH2SO2CHThree             CFThree              Ph-3,5-Cl2-4-OCHThree
H C (CHThree)2CH2SO2CHThree             CFThree              1-Naph
H C (CHThree)2CH2SO2CHThree             CFThree              2-Naph
H C (CHThree)2CH2SO2CHThree             CFThree             (L-1b) Br
H C (CHThree)2CH2SO2CHThree             CFThree             (L-1c) Cl
H C (CHThree)2CH2SO2CHThree             CFThree             (L-1c) Br
H C (CHThree)2CH2SO2CHThree             CFThree             (L-1c) I
H C (CHThree)2CH2SO2CHThree             CFThree             (L-1c) CFThree
H C (CHThree)2CH2SO2CHThree             CFThree             (L-2b) Br
H C (CHThree)2CH2SO2CHThree             CFThree             (L-3b) Cl
H C (CHThree)2CH2SO2CHThree             CFThree             (L-3b) Br
H C (CHThree)2CH2SO2CHThree             CFThree             (L-3c) F
H C (CHThree)2CH2SO2CHThree             CFThree             (L-3c) Cl
H C (CHThree)2CH2SO2CHThree             CFThree             (L-3c) Br
H C (CHThree)2CH2SO2CHThree             CFThree             (L-3c) I
H C (CHThree)2CH2SO2CHThree             CFThree             (L-3c) CFThree
H C (CHThree)2CH2SO2CHThree             CFThree             (L-3c) CN
H C (CHThree)2CH2SO2CHThree             CFThree              L-3d
H C (CHThree)2CH2SO2CHThree             CFThree             (L-4b) Cl
H C (CHThree)2CH2SO2CHThree             CFThree             (L-4b) Br
H C (CHThree)2CH2SO2CHThree             CFThree             (L-4b) CN
H C (CHThree)2CH2SO2CHThree             CFThree             (L-10b) Cl
H C (CHThree)2CH2SO2CHThree             CFThree             (L-10b) Br
H C (CHThree)2CH2SO2CHThree             CFThree             (L-15b) CFThree
H C (CHThree)2CH2SO2CHThree             CFThree             (L-16a) CHF2
H C (CHThree)2CH2SO2CHThree             CFThree             (L-16a) CF2Br
H C (CHThree)2CH2SO2CHThree             CFThree             (L-17a) Cl
H C (CHThree)2CH2SO2CHThree             CFThree             (L-21b) Cl
H C (CHThree)2CH2SO2CHThree             CFThree             (L-21b) Br
H C (CHThree)2CH2SO2CHThree             CFThree             (L-21b) I
H C (CHThree)2CH2SO2CHThree             CFThree             (L-21b) CFThree
H C (CHThree)2CH2SO2CHThree             CFThree             (L-22b) Cl
H C (CHThree)2CH2SO2CHThree             CFThree             (L-22b) Br
H C (CHThree)2CH2SO2CHThree             CFThree             (L-23b) Cl
H C (CHThree)2CH2SO2CHThree             CFThree             (L-23b) Br
H C (CHThree)2CH2SO2CHThree             CFThree             (L-23c) Cl
H C (CHThree)2CH2SO2CHThree             CFThree             (L-23c) Br
H C (CHThree)2CH2SO2CHThree             CFThree             (L-31a) Cl
H C (CHThree)2CH2SO2CHThree             CFThree             (L-31a) Br
H C (CHThree)2CH2SO2CHThree             CFThree             (L-45c) F
H C (CHThree)2CH2SO2CHThree             CFThree             (L-45c) Cl
H C (CHThree)2CH2SO2CHThree             CFThree             (L-45c) Br
H C (CHThree)2CH2SO2CHThree             CFThree             (L-45c) I
H C (CHThree)2CH2SO2CHThree             CFThree             (L-45c) CFThree
H C (CHThree)2CH2SO2CHThree             CFThree              L-45e
H C (CHThree)2CH2SO2CHThree             CFThree              L-45f
H C (CHThree)2CH2SO2CHThree             CFThree             (L-46c) F
H C (CHThree)2CH2SO2CHThree             CFThree             (L-46c) Cl
H C (CHThree)2CH2SO2CHThree             CFThree             (L-46c) Br
H C (CHThree)2CH2SO2CHThree             CFThree             (L-46c) I
H C (CHThree)2CH2SO2CHThree             CFThree             (L-46c) CFThree
H C (CHThree)2CH2SO2CHThree             CFThree             (L-46c) OCH2CFThree
H C (CHThree)2CH2SO2CHThree             CFThree             (L-46c) OCH (CFThree)2
H C (CHThree)2CH2SO2CHThree             CFThree              L-46d
H C (CHThree)2CH2SO2CHThree             CFThree              L-47a
H C (CHThree)2CH2SO2CHThree             CFThree              L-47d
H C (CHThree)2CH2SO2CHThree             CFThree             (L-48b) Br
H C (CHThree)2CH2SO2CHThree             CFThree             (L-50b) Cl
H C (CHThree)2CH2SO2CHThree             CFThree             (L-50b) Br
H C (CHThree)2CH2SO2CHThree             CFThree             (L-51b) Cl
H C (CHThree)2CH2SO2CHThree             CF2Cl Ph-4-Cl
H C (CHThree)2CH2SO2CHThree             CF2Cl Ph-4-Br
H C (CHThree)2CH2SO2CHThree             CF2Cl Ph-4-CFThree
H C (CHThree)2CH2SO2CHThree             CF2Cl Ph-4-OCFThree
H C (CHThree)2CH2SO2CHThree             CF2Cl Ph-4-OCF2Br
H C (CHThree)2CH2SO2CHThree             CF2Cl Ph-4-OCF2CHFCFThree
H C (CHThree)2CH2SO2CHThree             CF2Cl Ph-4-OCF2CHFOCFThree
H C (CHThree)2CH2SO2CHThree             CF2Cl Ph-4-OCF2CHFOCF2CF2CFThree
H C (CHThree)2CH2SO2CHThree             CF2Cl Ph-4-O (L-45g)
H C (CHThree)2CH2SO2CHThree             CF2Cl Ph-3,4-Cl2
H C (CHThree)2CH2SO2CHThree             CF2Cl Ph (-3-OCF2O-4-)
H C (CHThree)2CH2SO2CHThree             CF2Cl Ph (-3-OCF2CF2O-4-)
H C (CHThree)2CH2SO2CHThree             CF2Cl (L-45c) CFThree
H C (CHThree)2CH2SO2CHThree             CF2Cl L-45f
H C (CHThree)2CH2SO2CHThree             CF2Cl (L-46c) CFThree
H C (CHThree)2CH2SO2CHThree             CF2Cl L-46d
H C (CHThree)2CH2SO2CHThree             CFCl2            Ph-4-Br
H C (CHThree)2CH2SO2CHThree             CF2Br Ph-4-Cl
H C (CHThree)2CH2SO2CHThree             CF2Br Ph-4-Br
H C (CHThree)2CH2SO2CHThree             CF2Br Ph-4-CFThree
H C (CHThree)2CH2SO2CHThree             CF2Br Ph-4-OCFThree
H C (CHThree)2CH2SO2CHThree             CF2Br Ph-4-OCF2Br
H C (CHThree)2CH2SO2CHThree             CF2Br Ph-4-OCF2CHFCFThree
H C (CHThree)2CH2SO2CHThree             CF2Br Ph-4-OCF2CHFOCFThree
H C (CHThree)2CH2SO2CHThree             CF2Br Ph-4-OCF2CHFOCF2CF2CFThree
H C (CHThree)2CH2SO2CHThree             CF2Br Ph-4-O (L-45g)
H C (CHThree)2CH2SO2CHThree             CF2Br Ph-3,4-Cl2
H C (CHThree)2CH2SO2CHThree             CF2Br Ph (-3-OCF2O-4-)
H C (CHThree)2CH2SO2CHThree             CF2Br Ph (-3-OCF2CF2O-4-)
H C (CHThree)2CH2SO2CHThree             CF2Br (L-45c) CFThree
H C (CHThree)2CH2SO2CHThree             CF2Br L-45f
H C (CHThree)2CH2SO2CHThree             CF2Br (L-46c) CFThree
H C (CHThree)2CH2SO2CHThree             CF2Br L-46d
H C (CHThree)2CH2SO2CHThree             CFClBr Ph-4-CFThree
H C (CHThree)2CH2SO2CHThree             CFBr2            Ph-4-OCFThree
H C (CHThree)2CH2SO2CHThree             CF2CHF2         (L-45c) CFThree
H C (CHThree)2CH2SO2CHThree             CF2CFThree           Ph-4-Cl
H C (CHThree)2CH2SO2CHThree             CF2CFThree           Ph-4-Br
H C (CHThree)2CH2SO2CHThree             CF2CFThree           Ph-4-CFThree
H C (CHThree)2CH2SO2CHThree             CF2CFThree           Ph-4-OCFThree
H C (CHThree)2CH2SO2CHThree             CF2CFThree           Ph-4-OCF2Br
H C (CHThree)2CH2SO2CHThree             CF2CFThree           Ph-4-OCF2CHFCFThree
H C (CHThree)2CH2SO2CHThree             CF2CFThree           Ph-4-OCF2CHFOCFThree
H C (CHThree)2CH2SO2CHThree             CF2CFThree           Ph-4-OCF2CHFOCF2CF2CFThree
H C (CHThree)2CH2SO2CHThree             CF2CFThree           Ph-4-O (L-45g)
H C (CHThree)2CH2SO2CHThree             CF2CFThree           Ph-3,4-Cl2
H C (CHThree)2CH2SO2CHThree             CF2CFThree           Ph (-3-OCF2O-4-)
H C (CHThree)2CH2SO2CHThree             CF2CFThree           Ph (-3-OCF2CF2O-4-)
H C (CHThree)2CH2SO2CHThree             CF2CFThree          (L-45c) CFThree
H C (CHThree)2CH2SO2CHThree             CF2CFThree           L-45f
H C (CHThree)2CH2SO2CHThree             CF2CFThree          (L-46c) CFThree
H C (CHThree)2CH2SO2CHThree             CF2CFThree           L-46d
H C (CHThree)2CH2SO2CHThree             CF2CF2Cl Ph-4-Br
H C (CHThree)2CH2SO2CHThree             CFClCFThree          Ph-4-CFThree
H C (CHThree)2CH2SO2CHThree             CFClCF2Cl Ph-4-OCFThree
H C (CHThree)2CH2SO2CHThree             CF2CF2Br (L-45c) CFThree
H C (CHThree)2CH2SO2CHThree             CFBrCFThree          Ph-4-Br
H C (CHThree)2CH2SO2CHThree             CF2CHFCFThree        Ph-4-CFThree
H C (CHThree)2CH2SO2CHThree             CF2CF2CFThree        Ph-4-Cl
H C (CHThree)2CH2SO2CHThree             CF2CF2CFThree        Ph-4-Br
H C (CHThree)2CH2SO2CHThree             CF2CF2CFThree        Ph-4-CFThree
H C (CHThree)2CH2SO2CHThree             CF2CF2CFThree        Ph-4-OCFThree
H C (CHThree)2CH2SO2CHThree             CF2CF2CFThree        Ph-4-OCF2Br
H C (CHThree)2CH2SO2CHThree             CF2CF2CFThree        Ph-4-OCF2CHFCFThree
H C (CHThree)2CH2SO2CHThree             CF2CF2CFThree        Ph-4-OCF2CHFOCFThree
H C (CHThree)2CH2SO2CHThree             CF2CF2CFThree        Ph-4-OCF2CHFOCF2CF2CFThree
H C (CHThree)2CH2SO2CHThree             CF2CF2CFThree        Ph-4-O (L-45g)
H C (CHThree)2CH2SO2CHThree             CF2CF2CFThree        Ph-3,4-Cl2
H C (CHThree)2CH2SO2CHThree             CF2CF2CFThree        Ph (-3-OCF2O-4-)
H C (CHThree)2CH2SO2CHThree             CF2CF2CFThree        Ph (-3-OCF2CF2O-4-)
H C (CHThree)2CH2SO2CHThree             CF2CF2CFThree       (L-45c) CFThree
H C (CHThree)2CH2SO2CHThree             CF2CF2CFThree        L-45f
H C (CHThree)2CH2SO2CHThree             CF2CF2CFThree       (L-46c) CFThree
H C (CHThree)2CH2SO2CHThree             CF2CF2CFThree        L-46d
H C (CHThree)2CH2SO2CHThree             CF (CFThree)2         Ph-4-OCFThree
H C (CHThree)2CH2SO2CHThree             CF2CF2CF2CFThree    (L-45c) CFThree
H C (CHThree)2CH2SO2CHThree             T-1 Ph-4-Br
H C (CHThree)2CH2SO2CHThree             T-2 Ph-4-CFThree
H C (CHThree)2CH2SO2CHThree             CH2OCHThree          Ph-4-OCFThree
H C (CHThree)2CH2SO2CHThree             CH2OEt (L-45c) CFThree
H C (CHThree)2CH2SO2CHThree             CH2OCH2CFThree       Ph-4-Br
H C (CHThree)2CH2SO2CHThree             CH2OCH (CFThree)2     Ph-4-CFThree
H C (CHThree)2CH2SO2CHThree             CF2OCHThree          Ph-4-Cl
H C (CHThree)2CH2SO2CHThree             CF2OCHThree          Ph-4-Br
H C (CHThree)2CH2SO2CHThree             CF2OCHThree          Ph-4-CFThree
H C (CHThree)2CH2SO2CHThree             CF2OCHThree          Ph-4-OCFThree
H C (CHThree)2CH2SO2CHThree             CF2OCHThree          Ph-4-OCF2Br
H C (CHThree)2CH2SO2CHThree             CF2OCHThree          Ph-4-OCF2CHFCFThree
H C (CHThree)2CH2SO2CHThree             CF2OCHThree          Ph-4-OCF2CHFOCFThree
H C (CHThree)2CH2SO2CHThree             CF2OCHThree          Ph-4-OCF2CHFOCF2CF2CFThree
H C (CHThree)2CH2SO2CHThree             CF2OCHThree          Ph-4-O (L-45g)
H C (CHThree)2CH2SO2CHThree             CF2OCHThree          Ph-3,4-Cl2
H C (CHThree)2CH2SO2CHThree             CF2OCHThree          Ph (-3-OCF2O-4-)
H C (CHThree)2CH2SO2CHThree             CF2OCHThree          Ph (-3-OCF2CF2O-4-)
H C (CHThree)2CH2SO2CHThree             CF2OCHThree         (L-45c) CFThree
H C (CHThree)2CH2SO2CHThree             CF2OCHThree          L-45f
H C (CHThree)2CH2SO2CHThree             CF2OCHThree         (L-46c) CFThree
H C (CHThree)2CH2SO2CHThree             CF2OCHThree          L-46d
H C (CHThree)2CH2SO2CHThree             CH2SCHThree          Ph-4-OCFThree
H C (CHThree)2CH2SO2CHThree             CH2SO2CHThree       (L-45c) CFThree
H C (CHThree)2CH2SO2CHThree             CH2SCFThree          Ph-4-Br
H C (CHThree)2CH2SO2CHThree             CF2SCHThree          Ph-4-Cl
H C (CHThree)2CH2SO2CHThree             CF2SCHThree          Ph-4-Br
H C (CHThree)2CH2SO2CHThree             CF2SCHThree          Ph-4-CFThree
H C (CHThree)2CH2SO2CHThree             CF2SCHThree          Ph-4-OCFThree
H C (CHThree)2CH2SO2CHThree             CF2SCHThree          Ph-4-OCF2Br
H C (CHThree)2CH2SO2CHThree             CF2SCHThree          Ph-4-OCF2CHFCFThree
H C (CHThree)2CH2SO2CHThree             CF2SCHThree          Ph-4-OCF2CHFOCFThree
H C (CHThree)2CH2SO2CHThree             CF2SCHThree          Ph-4-OCF2CHFOCF2CF2CFThree
H C (CHThree)2CH2SO2CHThree             CF2SCHThree          Ph-4-O (L-45g)
H C (CHThree)2CH2SO2CHThree             CF2SCHThree          Ph-3,4-Cl2
H C (CHThree)2CH2SO2CHThree             CF2SCHThree          Ph (-3-OCF2O-4-)
H C (CHThree)2CH2SO2CHThree             CF2SCHThree          Ph (-3-OCF2CF2O-4-)
H C (CHThree)2CH2SO2CHThree             CF2SCHThree         (L-45c) CFThree
H C (CHThree)2CH2SO2CHThree             CF2SCHThree          L-45f
H C (CHThree)2CH2SO2CHThree             CF2SCHThree         (L-46c) CFThree
H C (CHThree)2CH2SO2CHThree             CF2SCHThree          L-46d
H C (CHThree)2CH2SO2CHThree             CF2SEt Ph-4-CFThree
H C (CHThree)2CH2SO2CHThree             CF2SPr-n Ph-4-OCFThree
H C (CHThree)2CH2SO2CHThree             CF2SPr-i (L-45c) CFThree
H C (CHThree)2CH2SO2CHThree             CF2SCH2Ph Ph-4-Br
H C (CHThree)2CH2SO2CHThree             CF2SPh Ph-4-CFThree
H C (CHThree)2CH2SO2CHThree             CF2C (O) OEt Ph-4-OCFThree
H C (CHThree)2CH2SO2CHThree             CF2SO2N (CHThree)2   (L-45c) CFThree
H C (CHThree)2CH2SO2CHThree             C (O) OEt Ph-4-Br
H C (CHThree)2CH2SO2CHThree             C (O) SEt Ph-4-CFThree
H C (CHThree)2CH2SEt CFThree              CH = CH (Ph-4-Cl)
H C (CHThree)2CH2SEt CFThree              Ph-4-Cl
H C (CHThree)2CH2SEt CFThree              Ph-4-Br
H C (CHThree)2CH2SEt CFThree              Ph-4-CFThree
H C (CHThree)2CH2SEt CFThree              Ph-4-OCFThree
H C (CHThree)2CH2SEt CFThree              Ph-4-OCF2Br
H C (CHThree)2CH2SEt CFThree              Ph-4-OCF2CHFCFThree
H C (CHThree)2CH2SEt CFThree              Ph-4-OCF2CHFOCFThree
H C (CHThree)2CH2SEt CFThree              Ph-4-OCF2CHFOCF2CF2CFThree
H C (CHThree)2CH2SEt CFThree              Ph-4-O (L-45g)
H C (CHThree)2CH2SEt CFThree              Ph-3,4-Cl2
H C (CHThree)2CH2SEt CFThree              Ph (-3-OCF2O-4-)
H C (CHThree)2CH2SEt CFThree              Ph (-3-OCF2CF2O-4-)
H C (CHThree)2CH2SEt CFThree             (L-45c) CFThree
H C (CHThree)2CH2SEt CFThree              L-45f
H C (CHThree)2CH2SEt CFThree             (L-46c) CFThree
H C (CHThree)2CH2SEt CFThree              L-46d
H C (CHThree)2CH2S (O) Et CFThree              CH = CH (Ph-4-Cl)
H C (CHThree)2CH2S (O) Et CFThree              Ph-4-Cl
H C (CHThree)2CH2S (O) Et CFThree              Ph-4-Br
H C (CHThree)2CH2S (O) Et CFThree              Ph-4-CFThree
H C (CHThree)2CH2S (O) Et CFThree              Ph-4-OCFThree
H C (CHThree)2CH2S (O) Et CFThree              Ph-4-OCF2Br
H C (CHThree)2CH2S (O) Et CFThree              Ph-4-OCF2CHFCFThree
H C (CHThree)2CH2S (O) Et CFThree              Ph-4-OCF2CHFOCFThree
H C (CHThree)2CH2S (O) Et CFThree              Ph-4-OCF2CHFOCF2CF2CFThree
H C (CHThree)2CH2S (O) Et CFThree              Ph-4-O (L-45g)
H C (CHThree)2CH2S (O) Et CFThree              Ph-3,4-Cl2
H C (CHThree)2CH2S (O) Et CFThree              Ph (-3-OCF2O-4-)
H C (CHThree)2CH2S (O) Et CFThree              Ph (-3-OCF2CF2O-4-)
H C (CHThree)2CH2S (O) Et CFThree             (L-45c) CFThree
H C (CHThree)2CH2S (O) Et CFThree              L-45f
H C (CHThree)2CH2S (O) Et CFThree             (L-46c) CFThree
H C (CHThree)2CH2S (O) Et CFThree              L-46d
H C (CHThree)2CH2SO2Et CFThree              CH = CH (Ph-4-Cl)
H C (CHThree)2CH2SO2Et CFThree              Ph-4-Cl
H C (CHThree)2CH2SO2Et CFThree              Ph-4-Br
H C (CHThree)2CH2SO2Et CFThree              Ph-4-CFThree
H C (CHThree)2CH2SO2Et CFThree              Ph-4-OCFThree
H C (CHThree)2CH2SO2Et CFThree              Ph-4-OCF2Br
H C (CHThree)2CH2SO2Et CFThree              Ph-4-OCF2CHFCFThree
H C (CHThree)2CH2SO2Et CFThree              Ph-4-OCF2CHFOCFThree
H C (CHThree)2CH2SO2Et CFThree              Ph-4-OCF2CHFOCF2CF2CFThree
H C (CHThree)2CH2SO2Et CFThree              Ph-4-O (L-45g)
H C (CHThree)2CH2SO2Et CFThree              Ph-3,4-Cl2
H C (CHThree)2CH2SO2Et CFThree              Ph (-3-OCF2O-4-)
H C (CHThree)2CH2SO2Et CFThree              Ph (-3-OCF2CF2O-4-)
H C (CHThree)2CH2SO2Et CFThree             (L-45c) CFThree
H C (CHThree)2CH2SO2Et CFThree              L-45f
H C (CHThree)2CH2SO2Et CFThree             (L-46c) CFThree
H C (CHThree)2CH2SO2Et CFThree              L-46d
H C (CHThree)2CH2SPr-n CFThree              Ph-4-Br
H C (CHThree)2CH2SPr-n CFThree              Ph-4-CFThree
H C (CHThree)2CH2SPr-n CFThree              Ph-4-OCFThree
H C (CHThree)2CH2SPr-n CFThree             (L-45c) CFThree
H C (CHThree)2CH2S (O) Pr-n CFThree              Ph-4-OCFThree
H C (CHThree)2CH2SO2Pr-n CFThree              Ph-4-Br
H C (CHThree)2CH2SO2Pr-n CFThree              Ph-4-CFThree
H C (CHThree)2CH2SO2Pr-n CFThree              Ph-4-OCFThree
H C (CHThree)2CH2SO2Pr-n CFThree             (L-45c) CFThree
H C (CHThree)2CH2SPr-i CFThree              Ph-4-Br
H C (CHThree)2CH2SPr-i CFThree              Ph-4-CFThree
H C (CHThree)2CH2SPr-i CFThree              Ph-4-OCFThree
H C (CHThree)2CH2SPr-i CFThree             (L-45c) CFThree
H C (CHThree)2CH2S (O) Pr-i CFThree             (L-45c) CFThree
H C (CHThree)2CH2SO2Pr-i CFThree              Ph-4-Br
H C (CHThree)2CH2SBu-t CFThree              Ph-4-CFThree
H C (CHThree)2CH2S (O) Bu-t CFThree              Ph-4-OCFThree
H C (CHThree)2CH2SCH2(Ph-4-Cl) CFThree             (L-45c) CFThree
H C (CHThree)2CH2SO2NH2             CFThree              Ph-4-Br
H C (CHThree)2CH2SO2NHCHThree           CFThree              Ph-4-CFThree
H C (CHThree)2CH2SO2NHEt CFThree              Ph-4-Br
H C (CHThree)2CH2SO2NHEt CFThree              Ph-4-CFThree
H C (CHThree)2CH2SO2NHEt CFThree              Ph-4-OCFThree
H C (CHThree)2CH2SO2NHEt CFThree             (L-45c) CFThree
H C (CHThree)2CH2SO2NHCH2CH2OCHThree    CFThree              Ph-4-OCFThree
H C (CHThree)2CH2SO2NHCH2CH2OC (O) CHThree      CFThree       (L-45c) CFThree
H C (CHThree)2CH2SO2NHCH2CH2SCHThree    CFThree              Ph-4-Br
H C (CHThree)2CH2SO2NHCH2CH2S (O) CHThree       CFThree        Ph-4-CFThree
H C (CHThree)2CH2SO2NHCH2CH2SO2CHThree  CFThree              Ph-4-OCFThree
H C (CHThree)2CH2SO2NHCH2CH2SEt CFThree             (L-45c) CFThree
H C (CHThree)2CH2SO2NHCH2CH2S (O) Et CFThree              Ph-4-Br
H C (CHThree)2CH2SO2NHCH2CH2SO2Et CFThree              Ph-4-CFThree
H C (CHThree)2CH2SO2NHCH2CH2SPh CFThree              Ph-4-OCFThree
H C (CHThree)2CH2SO2NHCH2CH2S (O) Ph CFThree             (L-45c) CFThree
H C (CHThree)2CH2SO2NHCH2CH2SO2Ph CFThree              Ph-4-Br
H C (CHThree)2CH2SO2NHCH2Ph CFThree              Ph-4-CFThree
H C (CHThree)2CH2SO2N (CHThree)2         CFThree              Ph-4-Br
H C (CHThree)2CH2SO2N (CHThree)2         CFThree              Ph-4-CFThree
H C (CHThree)2CH2SO2N (CHThree)2         CFThree              Ph-4-OCFThree
H C (CHThree)2CH2SO2N (CHThree)2         CFThree             (L-45c) CFThree
H C (CHThree)2CH2SO2N (Et)2          CFThree              CF2O (Ph-4-Cl)
H C (CHThree)2CH2SO2N (Et)2          CFThree              CH = CH (Ph-4-Cl)
H C (CHThree)2CH2SO2N (Et)2          CFThree              CH = CH (Ph-4-Br)
H C (CHThree)2CH2SO2N (Et)2          CFThree              CH = CH (Ph-4-CFThree)
H C (CHThree)2CH2SO2N (Et)2          CFThree              CH = CH (Ph-4-OCFThree)
H C (CHThree)2CH2SO2N (Et)2          CFThree              CH = CH (Ph-3,4-Cl2)
H C (CHThree)2CH2SO2N (Et)2          CFThree              Ph-4-F
H C (CHThree)2CH2SO2N (Et)2          CFThree              Ph-4-Cl
H C (CHThree)2CH2SO2N (Et)2          CFThree              Ph-4-Br
H C (CHThree)2CH2SO2N (Et)2          CFThree              Ph-4-CFThree
H C (CHThree)2CH2SO2N (Et)2          CFThree              Ph-4-OCFThree
H C (CHThree)2CH2SO2N (Et)2          CFThree              Ph-4-OCF2Br
H C (CHThree)2CH2SO2N (Et)2          CFThree              Ph-4-OCF2CHF2
H C (CHThree)2CH2SO2N (Et)2          CFThree              Ph-4-OCF2CHFCFThree
H C (CHThree)2CH2SO2N (Et)2          CFThree              Ph-4-OCF2CHFOCFThree
H C (CHThree)2CH2SO2N (Et)2          CFThree              Ph-4-OCF2CHFOCF2CF2CFThree
H C (CHThree)2CH2SO2N (Et)2          CFThree              Ph-4-O (L-45g)
H C (CHThree)2CH2SO2N (Et)2          CFThree              Ph-3,4-F2
H C (CHThree)2CH2SO2N (Et)2          CFThree              Ph-3-F-4-Cl
H C (CHThree)2CH2SO2N (Et)2          CFThree              Ph-3,4-Cl2
H C (CHThree)2CH2SO2N (Et)2          CFThree              Ph (-3-OCF2O-4-)
H C (CHThree)2CH2SO2N (Et)2          CFThree              Ph (-3-OCF2CF2O-4-)
H C (CHThree)2CH2SO2N (Et)2          CFThree             (L-45c) CFThree
H C (CHThree)2CH2SO2N (Et)2          CFThree              L-45f
H C (CHThree)2CH2SO2N (Et)2          CFThree             (L-46c) CFThree
H C (CHThree)2CH2SO2N (Et)2          CFThree              L-46d
H C (CHThree)2CH2SO2(T-19) CFThree              Ph-4-OCFThree
H C (CHThree)2CH2SO2(T-21) CFThree             (L-46c) CFThree
H C (CHThree)2CH2SPh CFThree              Ph-4-Br
H C (CHThree)2CH2S (O) Ph CFThree              Ph-4-CFThree
H C (CHThree)2CH2SO2Ph CFThree              Ph-4-OCFThree
H C (CHThree)2CH2S (L-45a) CFThree             (L-45c) CFThree
H C (CHThree)2CH2S (O) (L-45a) CFThree              Ph-4-Br
H C (CHThree)2CH2SO2(L-45a) CFThree              Ph-4-CFThree
H CH2CH2CH2SCHThree                CFThree              Ph-4-OCFThree
H CH (CHThree) CH2CH2SCHThree            CFThree              Ph-4-Br
H CH (CHThree) CH2CH2SCHThree            CFThree              Ph-4-CFThree
H CH (CHThree) CH2CH2SCHThree            CFThree              Ph-4-OCFThree
H CH (CHThree) CH2CH2SCHThree            CFThree             (L-45c) CFThree
H CH (CHThree) CH2CH2S (O) CHThree         CFThree              Ph-4-Br
H CH (CHThree) CH2CH2S (O) CHThree         CFThree              Ph-4-CFThree
H CH (CHThree) CH2CH2S (O) CHThree         CFThree              Ph-4-OCFThree
H CH (CHThree) CH2CH2S (O) CHThree         CFThree             (L-45c) CFThree
H CH (CHThree) CH2CH2SO2CHThree          CFThree              Ph-4-Br
H CH (CHThree) CH2CH2SO2CHThree          CFThree              Ph-4-CFThree
H CH (CHThree) CH2CH2SO2CHThree          CFThree              Ph-4-OCFThree
H CH (CHThree) CH2CH2SO2CHThree          CFThree             (L-45c) CFThree
H CH (CHThree) CH2CH2SEt CFThree              Ph-4-Br
H CH (CHThree) CH2CH2SEt CFThree              Ph-4-CFThree
H CH (CHThree) CH2CH2SEt CFThree              Ph-4-OCFThree
H CH (CHThree) CH2CH2SEt CFThree             (L-45c) CFThree
H CH (CHThree) CH2CH2S (O) Et CFThree              Ph-4-Br
H CH (CHThree) CH2CH2S (O) Et CFThree              Ph-4-CFThree
H CH (CHThree) CH2CH2S (O) Et CFThree              Ph-4-OCFThree
H CH (CHThree) CH2CH2S (O) Et CFThree             (L-45c) CFThree
H CH (CHThree) CH2CH2SO2Et CFThree              Ph-4-Br
H CH (CHThree) CH2CH2SO2Et CFThree              Ph-4-CFThree
H CH (CHThree) CH2CH2SO2Et CFThree              Ph-4-OCFThree
H CH (CHThree) CH2CH2SO2Et CFThree             (L-45c) CFThree
H CH (Et) CH2CH2SCHThree             CFThree             (L-45c) CFThree
H CH (CH2OH) CH2CH2SCHThree          CFThree              Ph-4-Br
H C (CHThree)2CH2CH2SCHThree            CFThree              Ph-4-CFThree
H C (CHThree)2CH2CH2SEt CFThree              Ph-4-OCFThree
H CH (CHThree) (CH2)ThreeSCHThree            CFThree              Ph-4-Br
H CH (CHThree) (CH2)ThreeSCHThree            CFThree              Ph-4-CFThree
H CH (CHThree) (CH2)ThreeSCHThree            CFThree              Ph-4-OCFThree
H CH (CHThree) (CH2)ThreeSCHThree            CFThree             (L-45c) CFThree
H CH (CHThree) (CH2)ThreeS (O) CHThree         CFThree             (L-45c) CFThree
H CH (CHThree) (CH2)ThreeSO2CHThree          CFThree              Ph-4-Br
H CH (CHThree) (CH2)ThreeSO2CHThree          CFThree              Ph-4-CFThree
H CH (CHThree) (CH2)ThreeSO2CHThree          CFThree              Ph-4-OCFThree
H CH (CHThree) (CH2)ThreeSO2CHThree          CFThree             (L-45c) CFThree
H CH (CHThree) (CH2)ThreeSEt CFThree              Ph-4-Br
H CH (CHThree) (CH2)ThreeSEt CFThree              Ph-4-CFThree
H CH (CHThree) (CH2)ThreeSEt CFThree              Ph-4-OCFThree
H CH (CHThree) (CH2)ThreeSEt CFThree             (L-45c) CFThree
H CH (CHThree) (CH2)ThreeS (O) Et CFThree              Ph-4-Br
H CH (CHThree) (CH2)ThreeSO2Et CFThree              Ph-4-Br
H CH (CHThree) (CH2)ThreeSO2Et CFThree              Ph-4-CFThree
H CH (CHThree) (CH2)ThreeSO2Et CFThree              Ph-4-OCFThree
H CH (CHThree) (CH2)ThreeSO2Et CFThree             (L-45c) CFThree
H C (CHThree)2(CH2)ThreeSCHThree            CFThree              Ph-4-CFThree
H C (CHThree)2(CH2)ThreeS (O) CHThree         CFThree              Ph-4-OCFThree
H CH (CHThree) CH2SO2CHThree             CFThree             (L-45c) CFThree
H C (CHThree)2(CH2)ThreeSEt CFThree              Ph-4-Br
H C (CHThree)2(CH2)ThreeS (O) Et CFThree              Ph-4-CFThree
H C (CHThree)2(CH2)ThreeSO2Et CFThree              Ph-4-OCFThree
H C (CHThree)2(CH2)ThreeSO2NHCHThree        CFThree             (L-45c) CFThree
H C (CHThree)2(CH2)ThreeSO2NHEt CFThree              Ph-4-Br
H C (CHThree)2(CH2)ThreeSO2N (CHThree)2      CFThree              Ph-4-CFThree
H C (CHThree)2(CH2)ThreeSO2N (Et)2       CFThree              Ph-4-OCFThree
H C (CHThree)2CH2CH2CH (CHThree) SCHThree     CFThree             (L-45c) CFThree
H CH (CHThree) (CH2)FourSCHThree            CFThree              Ph-4-Br
H CH (CHThree) (CH2)FourSO2CHThree          CFThree              Ph-4-CFThree
H CH (CHThree) (CH2)FourSEt CFThree              Ph-4-OCFThree
H CH (CHThree) (CH2)FourS (O) Et CFThree             (L-45c) CFThree
H CH (CHThree) (CH2)FourSO2Et CFThree              Ph-4-Br
H T-6 CFThree              Ph-4-CFThree
H T-7 CFThree              Ph-4-OCFThree
H T-8 CFThree             (L-45c) CFThree
H T-9 CFThree              Ph-4-Br
H T-11 CFThree              Ph-4-CFThree
H T-12 CFThree              Ph-4-OCFThree
H T-13 CFThree             (L-45c) CFThree
H T-14 CFThree              Ph-4-Br
H T-15 CFThree              Ph-4-CFThree
H M-8a CFThree              Ph-4-OCFThree
H M-9a CFThree             (L-45c) CFThree
H M-9b CFThree              Ph-4-Br
H M-9c CFThree              Ph-4-CFThree
H M-19a CFThree              Ph-4-OCFThree
H CH2NHC (O) OCHThree                CFThree             (L-45c) CFThree
H CH2NHC (O) OEt CFThree              Ph-4-Br
H CH2NHC (O) OPr-i CFThree              Ph-4-Br
H CH2NHC (O) OPr-i CFThree              Ph-4-CFThree
H CH2NHC (O) OPr-i CFThree              Ph-4-OCFThree
H CH2NHC (O) OPr-i CFThree             (L-45c) CFThree
H CH2CH2NHC (O) CHThree              CFThree              Ph-4-CFThree
H CH2CH2NHC (O) N (CHThree)2          CFThree              Ph-4-OCFThree
H CH2CH2NHC (O) Ph CFThree             (L-45c) CFThree
H CH2CH2N (CHThree) OCHThree             CFThree              Ph-4-Br
H CH (CHThree) CH2NHC (O) CHThree          CFThree              Ph-4-Br
H CH (CHThree) CH2NHC (O) CHThree          CFThree              Ph-4-CFThree
H CH (CHThree) CH2NHC (O) CHThree          CFThree              Ph-4-OCFThree
H CH (CHThree) CH2NHC (O) CHThree          CFThree             (L-45c) CFThree
H CH (CHThree) CH2NHC (O) Et CFThree              Ph-4-CFThree
H CH (CHThree) CH2NHC (O) OCHThree         CFThree              Ph-4-OCFThree
H CH (CHThree) CH2NHC (O) N (CHThree)2      CFThree             (L-45c) CFThree
H CH (CHThree) CH2NHC (S) NHEt CFThree              Ph-4-Br
H CH (CHThree) CH2NHSO2CHThree           CFThree              Ph-4-CFThree
H CH (CHThree) CH2NHSO2Et CFThree              Ph-4-OCFThree
H CH (CHThree) CH2NHSO2Ph CFThree             (L-45c) CFThree
H CH (CHThree) CH2NHSO2N (CHThree)2       CFThree              Ph-4-Br
H CH (CHThree) CH2NHP (S) (OCHThree)2      CFThree              Ph-4-CFThree
H CH (CHThree) CH2NHP (S) (OEt)2       CFThree              Ph-4-OCFThree
H CH (CHThree) CH2N (CHThree)2            CFThree             (L-45c) CFThree
H CH (CHThree) CH2N (CHThree) SO2CHThree       CHThree              Ph-4-Br
H CH (CHThree) CH2N (CHThree) SO2CHThree       CHThree              Ph-4-CFThree
H CH (CHThree) CH2N (CHThree) SO2CHThree       CHThree              Ph-4-OCFThree
H CH (CHThree) CH2N (CHThree) SO2CHThree       CHThree             (L-45c) Cl
H CH (CHThree) CH2N (CHThree) SO2CHThree       CHThree             (L-45c) Br
H CH (CHThree) CH2N (CHThree) SO2CHThree       CHThree             (L-45c) CFThree
H CH (CHThree) CH2N (CHThree) SO2CHThree       Et Ph-4-Br
H CH (CHThree) CH2N (CHThree) SO2CHThree       n-Pr Ph-4-CFThree
H CH (CHThree) CH2N (CHThree) SO2CHThree       i-Pr Ph-4-OCFThree
H CH (CHThree) CH2N (CHThree) SO2CHThree       c-Pr (L-45c) CFThree
H CH (CHThree) CH2N (CHThree) SO2CHThree       CHF2             Ph-4-Br
H CH (CHThree) CH2N (CHThree) SO2CHThree       CFThree              CF2O (Ph-4-Cl)
H CH (CHThree) CH2N (CHThree) SO2CHThree       CFThree              CH = CH (Ph-4-Cl)
H CH (CHThree) CH2N (CHThree) SO2CHThree       CFThree              CH = CH (Ph-4-Br)
H CH (CHThree) CH2N (CHThree) SO2CHThree       CFThree              CH = CH (Ph-4-CFThree)
H CH (CHThree) CH2N (CHThree) SO2CHThree       CFThree              CH = CH (Ph-4-OCFThree)
H CH (CHThree) CH2N (CHThree) SO2CHThree       CFThree              CH = CH (Ph-3,4-Cl2)
H CH (CHThree) CH2N (CHThree) SO2CHThree       CFThree              Ph-4-F
H CH (CHThree) CH2N (CHThree) SO2CHThree       CFThree              Ph-4-Cl
H CH (CHThree) CH2N (CHThree) SO2CHThree       CFThree              Ph-4-Br
H CH (CHThree) CH2N (CHThree) SO2CHThree       CFThree              Ph-4-I
H CH (CHThree) CH2N (CHThree) SO2CHThree       CFThree              Ph-4-CFThree
H CH (CHThree) CH2N (CHThree) SO2CHThree       CFThree              Ph-4-OCHF2
H CH (CHThree) CH2N (CHThree) SO2CHThree       CFThree              Ph-4-OCFThree
H CH (CHThree) CH2N (CHThree) SO2CHThree       CFThree              Ph-4-OCF2Br
H CH (CHThree) CH2N (CHThree) SO2CHThree       CFThree              Ph-4-OCF2CHF2
H CH (CHThree) CH2N (CHThree) SO2CHThree       CFThree              Ph-4-OCF2CHFCl
H CH (CHThree) CH2N (CHThree) SO2CHThree       CFThree              Ph-4-OCF2CHFCFThree
H CH (CHThree) CH2N (CHThree) SO2CHThree       CFThree              Ph-4-OCF2CHFOCFThree
H CH (CHThree) CH2N (CHThree) SO2CHThree       CFThree              Ph-4-OCF2CHFOCF2CF2CFThree
H CH (CHThree) CH2N (CHThree) SO2CHThree       CFThree              Ph-4-O (L-45g)
H CH (CHThree) CH2N (CHThree) SO2CHThree       CFThree              Ph-3,4-F2
H CH (CHThree) CH2N (CHThree) SO2CHThree       CFThree              Ph-3-F-4-Cl
H CH (CHThree) CH2N (CHThree) SO2CHThree       CFThree              Ph-3,4-Cl2
H CH (CHThree) CH2N (CHThree) SO2CHThree       CFThree              Ph (-3-OCF2O-4-)
H CH (CHThree) CH2N (CHThree) SO2CHThree       CFThree              Ph (-3-OCF2CF2O-4-)
H CH (CHThree) CH2N (CHThree) SO2CHThree       CFThree             (L-45c) Cl
H CH (CHThree) CH2N (CHThree) SO2CHThree       CFThree             (L-45c) Br
H CH (CHThree) CH2N (CHThree) SO2CHThree       CFThree             (L-45c) CFThree
H CH (CHThree) CH2N (CHThree) SO2CHThree       CFThree              L-45e
H CH (CHThree) CH2N (CHThree) SO2CHThree       CFThree              L-45f
H CH (CHThree) CH2N (CHThree) SO2CHThree       CFThree             (L-46c) Cl
H CH (CHThree) CH2N (CHThree) SO2CHThree       CFThree             (L-46c) Br
H CH (CHThree) CH2N (CHThree) SO2CHThree       CFThree             (L-46c) CFThree
H CH (CHThree) CH2N (CHThree) SO2CHThree       CFThree              L-46d
H CH (CHThree) CH2N (CHThree) SO2CHThree       CF2Cl Ph-4-CFThree
H CH (CHThree) CH2N (CHThree) SO2CHThree       CF2Br Ph-4-OCFThree
H CH (CHThree) CH2N (CHThree) SO2CHThree       CF2CFThree          (L-45c) CFThree
H CH (CHThree) CH2N (CHThree) SO2CHThree       CF2CF2CFThree        Ph-4-Br
H CH (CHThree) CH2N (CHThree) SO2CHThree       CF2OCHThree          Ph-4-CFThree
H CH (CHThree) CH2N (CHThree) SO2CHThree       CF2SCHThree          Ph-4-OCFThree
H C (CHThree)2CH2NHC (O) CHThree          CFThree             (L-45c) CFThree
H C (CHThree)2CH2NHC (O) Et CFThree              Ph-4-Br
H C (CHThree)2CH2NHC (O) Pr-c CFThree              Ph-4-CFThree
H C (CHThree)2CH2NHC (O) Bu-t CFThree              Ph-4-OCFThree
H C (CHThree)2CH2NHC (O) CFThree          CFThree             (L-45c) CFThree
H C (CHThree)2CH2NHC (O) Ph CFThree              Ph-4-Br
H C (CHThree)2CH2NHC (O) OCHThree         CFThree              CF2O (Ph-4-Cl)
H C (CHThree)2CH2NHC (O) OCHThree         CFThree              CH = CH (Ph-4-Cl)
H C (CHThree)2CH2NHC (O) OCHThree         CFThree              CH = CH (Ph-4-Br)
H C (CHThree)2CH2NHC (O) OCHThree         CFThree              CH = CH (Ph-4-CFThree)
H C (CHThree)2CH2NHC (O) OCHThree         CFThree              CH = CH (Ph-4-OCFThree)
H C (CHThree)2CH2NHC (O) OCHThree         CFThree              CH = CH (Ph-3,4-Cl2)
H C (CHThree)2CH2NHC (O) OCHThree         CFThree              Ph-4-F
H C (CHThree)2CH2NHC (O) OCHThree         CFThree              Ph-4-Cl
H C (CHThree)2CH2NHC (O) OCHThree         CFThree              Ph-4-Br
H C (CHThree)2CH2NHC (O) OCHThree         CFThree              Ph-4-CFThree
H C (CHThree)2CH2NHC (O) OCHThree         CFThree              Ph-4-OCFThree
H C (CHThree)2CH2NHC (O) OCHThree         CFThree              Ph-4-OCF2Br
H C (CHThree)2CH2NHC (O) OCHThree         CFThree              Ph-4-OCF2CHF2
H C (CHThree)2CH2NHC (O) OCHThree         CFThree              Ph-4-OCF2CHFCFThree
H C (CHThree)2CH2NHC (O) OCHThree         CFThree              Ph-4-OCF2CHFOCFThree
H C (CHThree)2CH2NHC (O) OCHThree         CFThree              Ph-4-OCF2CHFOCF2CF2CFThree
H C (CHThree)2CH2NHC (O) OCHThree         CFThree              Ph-4-O (L-45g)
H C (CHThree)2CH2NHC (O) OCHThree         CFThree              Ph-3,4-F2
H C (CHThree)2CH2NHC (O) OCHThree         CFThree              Ph-3-F-4-Cl
H C (CHThree)2CH2NHC (O) OCHThree         CFThree              Ph-3,4-Cl2
H C (CHThree)2CH2NHC (O) OCHThree         CFThree              Ph (-3-OCF2O-4-)
H C (CHThree)2CH2NHC (O) OCHThree         CFThree              Ph (-3-OCF2CF2O-4-)
H C (CHThree)2CH2NHC (O) OCHThree         CFThree             (L-45c) CFThree
H C (CHThree)2CH2NHC (O) OCHThree         CFThree              L-45f
H C (CHThree)2CH2NHC (O) OCHThree         CFThree             (L-46c) CFThree
H C (CHThree)2CH2NHC (O) OCHThree         CFThree              L-46d
H C (CHThree)2CH2NHC (O) OEt CFThree              Ph-4-CFThree
H C (CHThree)2CH2NHC (O) OPr-n CFThree              Ph-4-OCFThree
H CH2CH2CH2NHC (O) OCHThree          CFThree             (L-45c) CFThree
H CH2CH2CH2NHC (O) OBu-t CFThree              Ph-4-Br
H CH2CH2CH2N (CHThree)2             CFThree              Ph-4-CFThree
H CH2CH2CH2N (CHThree) OCHThree          CFThree              Ph-4-OCFThree
H (M-22a) CHO CFThree             (L-45c) CFThree
H (M-22a) C (O) CHThree                CFThree              Ph-4-Br
H (M-22a) C (O) OCHThree               CFThree              Ph-4-CFThree
H (M-22a) C (O) OEt CFThree              Ph-4-OCFThree
H (M-22a) C (O) SCHThree               CFThree             (L-45c) CFThree
H CH2Si (CHThree)Three                  CFThree              Ph-4-Br
H C (CHThree)2CHO CFThree              Ph-4-CFThree
H CH (CHThree) C (O) CHThree               CFThree              Ph-4-OCFThree
H CH (CHO) CH2SO2CHThree             CFThree             (L-45c) CFThree
H C (CHThree) (CHO) CH2SO2CHThree         CFThree              Ph-4-Br
H C (CHThree) (CHO) CH2SO2Et CFThree              Ph-4-CFThree
H CH2CH = NOCHThree                  CFThree              Ph-4-OCFThree
H CH2C (Ph) = NOCHThree               CFThree             (L-45c) CFThree
H CH (CHThree) CH = NOCHThree              CHThree              Ph-4-Br
H CH (CHThree) CH = NOCHThree              CHThree              Ph-4-CFThree
H CH (CHThree) CH = NOCHThree              CHThree              Ph-4-OCFThree
H CH (CHThree) CH = NOCHThree              CHThree             (L-45c) Cl
H CH (CHThree) CH = NOCHThree              CHThree             (L-45c) Br
H CH (CHThree) CH = NOCHThree              CHThree             (L-45c) CFThree
H CH (CHThree) CH = NOCHThree              Et Ph-4-Br
H CH (CHThree) CH = NOCHThree              n-Pr Ph-4-CFThree
H CH (CHThree) CH = NOCHThree              i-Pr Ph-4-OCFThree
H CH (CHThree) CH = NOCHThree              c-Pr (L-45c) CFThree
H CH (CHThree) CH = NOCHThree              CHF2             Ph-4-Br
H CH (CHThree) CH = NOCHThree              CFThree              CF2O (Ph-4-Cl)
H CH (CHThree) CH = NOCHThree              CFThree              CH = CH (Ph-4-Cl)
H CH (CHThree) CH = NOCHThree              CFThree              CH = CH (Ph-4-Br)
H CH (CHThree) CH = NOCHThree              CFThree              CH = CH (Ph-4-CFThree)
H CH (CHThree) CH = NOCHThree              CFThree              CH = CH (Ph-4-OCFThree)
H CH (CHThree) CH = NOCHThree              CFThree              CH = CH (Ph-3,4-Cl2)
H CH (CHThree) CH = NOCHThree              CFThree              Ph-4-F
H CH (CHThree) CH = NOCHThree              CFThree              Ph-4-Cl
H CH (CHThree) CH = NOCHThree              CFThree              Ph-4-Br
H CH (CHThree) CH = NOCHThree              CFThree              Ph-4-I
H CH (CHThree) CH = NOCHThree              CFThree              Ph-4-CFThree
H CH (CHThree) CH = NOCHThree              CFThree              Ph-4-OCHF2
H CH (CHThree) CH = NOCHThree              CFThree              Ph-4-OCFThree
H CH (CHThree) CH = NOCHThree              CFThree              Ph-4-OCF2Br
H CH (CHThree) CH = NOCHThree              CFThree              Ph-4-OCF2CHF2
H CH (CHThree) CH = NOCHThree              CFThree              Ph-4-OCF2CHFCl
H CH (CHThree) CH = NOCHThree              CFThree              Ph-4-OCF2CHFCFThree
H CH (CHThree) CH = NOCHThree              CFThree              Ph-4-OCF2CHFOCFThree
H CH (CHThree) CH = NOCHThree              CFThree              Ph-4-OCF2CHFOCF2CF2CFThree
H CH (CHThree) CH = NOCHThree              CFThree              Ph-4-O (L-45g)
H CH (CHThree) CH = NOCHThree              CFThree              Ph-3,4-F2
H CH (CHThree) CH = NOCHThree              CFThree              Ph-3-F-4-Cl
H CH (CHThree) CH = NOCHThree              CFThree              Ph-3,4-Cl2
H CH (CHThree) CH = NOCHThree              CFThree              Ph (-3-OCF2O-4-)
H CH (CHThree) CH = NOCHThree              CFThree              Ph (-3-OCF2CF2O-4-)
H CH (CHThree) CH = NOCHThree              CFThree             (L-45c) Cl
H CH (CHThree) CH = NOCHThree              CFThree             (L-45c) Br
H CH (CHThree) CH = NOCHThree              CFThree             (L-45c) CFThree
H CH (CHThree) CH = NOCHThree              CFThree              L-45e
H CH (CHThree) CH = NOCHThree              CFThree              L-45f
H CH (CHThree) CH = NOCHThree              CFThree             (L-46c) Cl
H CH (CHThree) CH = NOCHThree              CFThree             (L-46c) Br
H CH (CHThree) CH = NOCHThree              CFThree             (L-46c) CFThree
H CH (CHThree) CH = NOCHThree              CFThree              L-46d
H CH (CHThree) CH = NOCHThree              CF2Cl Ph-4-CFThree
H CH (CHThree) CH = NOCHThree              CF2Br Ph-4-OCFThree
H CH (CHThree) CH = NOCHThree              CF2CFThree          (L-45c) CFThree
H CH (CHThree) CH = NOCHThree              CF2CF2CFThree        Ph-4-Br
H CH (CHThree) CH = NOCHThree              CF2OCHThree          Ph-4-CFThree
H CH (CHThree) CH = NOCHThree              CF2SCHThree          Ph-4-OCFThree
H CH (CHThree) CH = NOPr-n CFThree              Ph-4-Br
H CH (CHThree) CH = NOPr-n CFThree              Ph-4-CFThree
H CH (CHThree) CH = NOPr-n CFThree              Ph-4-OCFThree
H CH (CHThree) CH = NOPr-n CFThree             (L-45c) CFThree
H CH (CHThree) CH = NOCH2Pr-c CFThree             (L-45c) CFThree
H CH (CHThree) CH = NOCH2CH2OEt CFThree              Ph-4-Br
H CH (CHThree) CH = NOCH2CH2SEt CFThree              Ph-4-CFThree
H CH (CHThree) CH = NOCH2CH = CH2        CFThree              Ph-4-OCFThree
H CH (CHThree) CH = NOCH2Ph CFThree             (L-45c) CFThree
H CH (CHThree) C (CHThree) = NOCHThree          CFThree              Ph-4-Br
H C (CHThree)2CH = NOH CFThree              Ph-4-Br
H C (CHThree)2CH = NOH CFThree              Ph-4-CFThree
H C (CHThree)2CH = NOH CFThree              Ph-4-OCFThree
H C (CHThree)2CH = NOH CFThree             (L-45c) CFThree
H C (CHThree)2CH = NOCHThree              CFThree              CF2O (Ph-4-Cl)
H C (CHThree)2CH = NOCHThree              CFThree              CH = CH (Ph-4-Cl)
H C (CHThree)2CH = NOCHThree              CFThree              CH = CH (Ph-4-Br)
H C (CHThree)2CH = NOCHThree              CFThree              CH = CH (Ph-4-CFThree)
H C (CHThree)2CH = NOCHThree              CFThree              CH = CH (Ph-4-OCFThree)
H C (CHThree)2CH = NOCHThree              CFThree              CH = CH (Ph-3,4-Cl2)
H C (CHThree)2CH = NOCHThree              CFThree              Ph-4-F
H C (CHThree)2CH = NOCHThree              CFThree              Ph-4-Cl
H C (CHThree)2CH = NOCHThree              CFThree              Ph-4-Br
H C (CHThree)2CH = NOCHThree              CFThree              Ph-4-CFThree
H C (CHThree)2CH = NOCHThree              CFThree              Ph-4-OCFThree
H C (CHThree)2CH = NOCHThree              CFThree              Ph-4-OCF2Br
H C (CHThree)2CH = NOCHThree              CFThree              Ph-4-OCF2CHF2
H C (CHThree)2CH = NOCHThree              CFThree              Ph-4-OCF2CHFCFThree
H C (CHThree)2CH = NOCHThree              CFThree              Ph-4-OCF2CHFOCFThree
H C (CHThree)2CH = NOCHThree              CFThree              Ph-4-OCF2CHFOCF2CF2CFThree
H C (CHThree)2CH = NOCHThree              CFThree              Ph-4-O (L-45g)
H C (CHThree)2CH = NOCHThree              CFThree              Ph-3,4-F2
H C (CHThree)2CH = NOCHThree              CFThree              Ph-3-F-4-Cl
H C (CHThree)2CH = NOCHThree              CFThree              Ph-3,4-Cl2
H C (CHThree)2CH = NOCHThree              CFThree              Ph (-3-OCF2O-4-)
H C (CHThree)2CH = NOCHThree              CFThree              Ph (-3-OCF2CF2O-4-)
H C (CHThree)2CH = NOCHThree              CFThree             (L-45c) CFThree
H C (CHThree)2CH = NOCHThree              CFThree              L-45f
H C (CHThree)2CH = NOCHThree              CFThree             (L-46c) CFThree
H C (CHThree)2CH = NOCHThree              CFThree              L-46d
H C (CHThree)2CH = NOEt CFThree              Ph-4-CFThree
H C (CHThree)2CH = NOCH2C (O) OBu-t CFThree              Ph-4-OCFThree
H C (CHThree)2CH = NOCH2C (O) N (Et)2    CFThree             (L-45c) CFThree
H C (CHThree) (CH2SO2CHThree) CH = NOH CFThree              Ph-4-Br
H C (CHThree) (CH2SO2Et) CH = NOH CFThree              Ph-4-CFThree
H CH2CH2CH = NOCHThree               CFThree              Ph-4-OCFThree
H CH (CHThree) CH2CH = NOCHThree           CFThree             (L-45c) CFThree
H CH2CH2CH2CH = NOEt CFThree              Ph-4-Br
H CH2C (O) OEt CFThree              Ph-4-CFThree
H CH (CHThree) C (O) OCHThree              CFThree              Ph-4-OCFThree
H CH (CHThree) C (O) OEt CFThree             (L-45c) CFThree
H CH2CH2C (O) OEt CFThree              Ph-4-Br
H CH (CHThree) CH2C (O) OEt CFThree              Ph-4-CFThree
H CH (CHThree) C (O) NHEt CFThree              Ph-4-OCFThree
H CH (CHThree) C (O) NHPr-n CFThree             (L-45c) CFThree
H CH (CHThree) C (O) NHBu-n CFThree              Ph-4-Br
H CH (CHThree) C (O) NHCH2Ph CFThree              Ph-4-CFThree
H CH (CHThree) C (O) N (CHThree)2           CFThree              Ph-4-OCFThree
H CH (CHThree) C (O) N (Et)2            CFThree             (L-45c) CFThree
H CH (CHThree) C (O) N (Pr-n)2          CFThree              Ph-4-Br
H CH (CHThree) C (O) (T-16) CFThree              Ph-4-CFThree
H CH (CHThree) C (O) (T-17) CFThree              Ph-4-OCFThree
H CH (CHThree) C (O) (T-18) CFThree             (L-45c) CFThree
H CH (CHThree) C (O) (T-19) CFThree              Ph-4-Br
H CH (CHThree) C (O) (T-20) CFThree              Ph-4-CFThree
H CH (CHThree) C (O) (T-21) CFThree              Ph-4-OCFThree
H CH (CHThree) CH2C (O) NHCHThree          CFThree             (L-45c) CFThree
H CH (CHThree) CH2C (O) NHEt CFThree              Ph-4-Br
H CH (CHThree) CH2C (O) N (CHThree)2        CFThree              Ph-4-CFThree
H CH (CHThree) CH2C (O) N (Et)2         CFThree              Ph-4-OCFThree
H CH (CHThree) CH2C (O) N (CHThree) Ph CFThree             (L-45c) CFThree
H CH (CHThree) CN CFThree              Ph-4-Br
H C (CHThree)2CN CFThree              Ph-4-CFThree
H CH2CH = CH2                    CFThree              Ph-4-OCFThree
CH2CH = CH2 CH2CH = CH2                    CFThree             (L-45c) CFThree
H C (CHThree)2CH = CH2                CFThree              CH = CH (Ph-4-Cl)
H C (CHThree)2CH = CH2                CFThree              Ph-4-Cl
H C (CHThree)2CH = CH2                CFThree              Ph-4-Br
H C (CHThree)2CH = CH2                CFThree              Ph-4-CFThree
H C (CHThree)2CH = CH2                CFThree              Ph-4-OCFThree
H C (CHThree)2CH = CH2                CFThree              Ph-4-OCF2Br
H C (CHThree)2CH = CH2                CFThree              Ph-4-OCF2CHFCFThree
H C (CHThree)2CH = CH2                CFThree              Ph-4-OCF2CHFOCFThree
H C (CHThree)2CH = CH2                CFThree              Ph-4-OCF2CHFOCF2CF2CFThree
H C (CHThree)2CH = CH2                CFThree              Ph-4-O (L-45g)
H C (CHThree)2CH = CH2                CFThree              Ph-3,4-Cl2
H C (CHThree)2CH = CH2                CFThree              Ph (-3-OCF2O-4-)
H C (CHThree)2CH = CH2                CFThree              Ph (-3-OCF2CF2O-4-)
H C (CHThree)2CH = CH2                CFThree             (L-45c) CFThree
H C (CHThree)2CH = CH2                CFThree              L-45f
H C (CHThree)2CH = CH2                CFThree             (L-46c) CFThree
H C (CHThree)2CH = CH2                CFThree              L-46d
H C (CHThree)2CH = CHC (O) NHEt CFThree              Ph-4-Br
H C (CHThree)2CH = CHPh (E) CFThree              Ph-4-CFThree
H CH2C≡CH CFThree              Ph-4-OCFThree
CHThree       CH2C≡CH CFThree              Ph-4-Br
CHThree       CH2C≡CH CFThree              Ph-4-CFThree
CHThree       CH2C≡CH CFThree              Ph-4-OCFThree
CHThree       CH2C≡CH CFThree             (L-45c) CFThree
H C (CHThree)2C≡CH CFThree              CH = CH (Ph-4-Cl)
H C (CHThree)2C≡CH CFThree              Ph-4-Cl
H C (CHThree)2C≡CH CFThree              Ph-4-Br
H C (CHThree)2C≡CH CFThree              Ph-4-CFThree
H C (CHThree)2C≡CH CFThree              Ph-4-OCFThree
H C (CHThree)2C≡CH CFThree              Ph-4-OCF2Br
H C (CHThree)2C≡CH CFThree              Ph-4-OCF2CHFCFThree
H C (CHThree)2C≡CH CFThree              Ph-4-OCF2CHFOCFThree
H C (CHThree)2C≡CH CFThree              Ph-4-OCF2CHFOCF2CF2CFThree
H C (CHThree)2C≡CH CFThree              Ph-4-O (L-45g)
H C (CHThree)2C≡CH CFThree              Ph-3,4-Cl2
H C (CHThree)2C≡CH CFThree              Ph (-3-OCF2O-4-)
H C (CHThree)2C≡CH CFThree              Ph (-3-OCF2CF2O-4-)
H C (CHThree)2C≡CH CFThree             (L-45c) CFThree
H C (CHThree)2C≡CH CFThree              L-45f
H C (CHThree)2C≡CH CFThree             (L-46c) CFThree
H C (CHThree)2C≡CH CFThree              L-46d
H C (CHThree)2C≡CPh CFThree             (L-45c) CFThree
H C (CHThree)2C≡C (Ph-4-CHThree) CFThree              Ph-4-Br
H C (CHThree)2C≡C (Ph-4-CFThree) CFThree              Ph-4-CFThree
H C (CHThree)2C≡C (Ph-4-OCHThree) CFThree              Ph-4-OCFThree
H C (CHThree)2C≡C (Ph-4-OCFThree) CFThree             (L-45c) CFThree
H C (CHThree)2C≡C (Ph-2,4-F2) CFThree              Ph-4-Br
H C (CHThree)2C≡C (Ph-2,4-Cl2) CFThree              Ph-4-CFThree
H C (CHThree)2C≡C (Ph-2,6-Cl2) CFThree              Ph-4-OCFThree
H C (CHThree)2C≡C (1-Naph) CFThree             (L-45c) CFThree
H C (CHThree)2C≡C (L-3a) CFThree              Ph-4-Br
H C (CHThree)2C≡C (L-4a) CFThree              Ph-4-CFThree
H C (CHThree)2C≡C (L-45a) CFThree              Ph-4-OCFThree
H C (CHThree)2C≡C (L-45g) CFThree             (L-45c) CFThree
H C (CHThree)2C≡C (L-46a) CFThree              Ph-4-Br
H CH2Ph CFThree              Ph-4-CFThree
CHThree       CH2Ph CFThree              Ph-4-OCFThree
Et CH2Ph CFThree             (L-45c) CFThree
H CH2(Ph-2-F) CFThree              Ph-4-Br
CHThree       CH2(Ph-2-F) CFThree              Ph-4-CFThree
H CH2(Ph-2-Cl) CFThree              Ph-4-OCFThree
H CH2(Ph-3-Cl) CFThree             (L-45c) CFThree
CHThree       CH2(Ph-3-Cl) CFThree              Ph-4-Br
H CH2(Ph-4-Cl) CFThree              Ph-4-CFThree
H CH2(Ph-2-CHThree) CFThree              Ph-4-OCFThree
H CH2(Ph-3-CHThree) CFThree             (L-45c) CFThree
H CH2(Ph-4-CHThree) CFThree              Ph-4-Br
H CH2(Ph-2-CFThree) CFThree              Ph-4-CFThree
H CH2(Ph-2-OCHThree) CFThree              Ph-4-OCFThree
H CH2(Ph-3-OCHThree) CFThree             (L-45c) CFThree
H CH2(Ph-4-OCHThree) CFThree              Ph-4-Br
H CH2(Ph-4-OCFThree) CFThree              Ph-4-CFThree
H CH2(Ph-2,3-Cl2) CFThree              Ph-4-OCFThree
H CH2(Ph-2,4-Cl2) CFThree             (L-45c) CFThree
H CH2(Ph-3,4-Cl2) CFThree              Ph-4-Br
H CH2(L-45a) CFThree              Ph-4-CFThree
H CH2(L-46a) CFThree              Ph-4-OCFThree
H CH2(L-47a) CFThree             (L-45c) CFThree
H CH (CHThree) Ph CFThree              Ph-4-Br
H CH (CHThree) Ph (R) CFThree              Ph-4-CFThree
H CH (CHThree) Ph (S) CFThree              Ph-4-OCFThree
H CH (CHThree) (Ph-2-Cl) CFThree             (L-45c) CFThree
H CH (CHThree) (Ph-3-Cl) CFThree              Ph-4-Br
H CH (CHThree) (Ph-4-Cl) CFThree              Ph-4-CFThree
H CH (CHThree) (L-1a) CFThree              Ph-4-OCFThree
H CH (CHThree) (L-3a) CFThree             (L-45c) CFThree
H CH (CHThree) (L-45a) CFThree              Ph-4-Br
H C (CHThree)2Ph CFThree              Ph-4-CFThree
H C (CHThree)2(Ph-3-Cl) CFThree              Ph-4-OCFThree
H C (CHThree)2(Ph-4-Cl) CFThree             (L-45c) CFThree
H CH2CH2Ph CFThree              Ph-4-Br
H CH2CH2(Ph-2-Cl) CFThree              Ph-4-CFThree
H CH2CH2(Ph-3-Cl) CFThree              Ph-4-OCFThree
H CH2CH2(Ph-4-Cl) CFThree             (L-45c) CFThree
H CH2CH2(L-46a) CFThree              Ph-4-Br
H C (CHThree)2CH2Ph CFThree              Ph-4-CFThree
H CH2CH2CH2Ph CFThree              Ph-4-OCFThree
H OCHThree                         CFThree             (L-45c) CFThree
H OPr-n CFThree              Ph-4-Br
H OCH2CH = CHCl CFThree              Ph-4-CFThree
H OCH2Ph CFThree              Ph-4-OCFThree
H NHCHO CFThree             (L-45c) CFThree
H NHC (O) CHThree                    CFThree              Ph-4-Br
H NHC (O) Ph CFThree              Ph-4-CFThree
H NHC (O) OCHThree                   CFThree              Ph-4-OCFThree
H NHC (O) OPh CFThree             (L-45c) CFThree
H NHC (O) OCH2Ph CFThree              Ph-4-Br
H N (CHThree)2                      CFThree              Ph-4-CFThree
H N (CHThree) CHO CFThree              Ph-4-OCFThree
H N (CHThree) C (O) CHThree                CFThree             (L-45c) CFThree
H N (CHThree) C (O) OCHThree               CFThree              Ph-4-Br
―――――――――――――――――――――――――――――――――――――――
Table 3
  In the table, substituent (X)mAnd (Y)nThe numbers representing the substitution positions correspond to the positions of the numbers described in the following structural formulas, and the symbol “-” represents no substitution.

Figure 2005126418
Figure 2005126418

Figure 2005126418
Figure 2005126418

―――――――――――――――――――――――――――――――――――――――
(X)m (Y)n R4 R5 R6
―――――――――――――――――――――――――――――――――――――――
− 2-CH3 CF3 Ph-4-Br H
5-F 2-CH3 CF3 Ph-4-CF3 H
6-F 2-CH3 CF3 Ph-4-OCF3 H
3,4-F2 2-CH3 CF3 Ph-4-Br H
3,4-F2 2-CH3 CF3 Ph-4-CF3 H
3,4-F2 2-CH3 CF3 Ph-4-OCF3 H
3,4-F2 2-CH3 CF3 (L-45c)CF3 H
3,6-F2 2-CH3 CF3 (L-45c)CF3 H
4,5-F2 2-CH3 CF3 Ph-4-Br H
4-Cl 2-CH3 CF3 Ph-4-CF3 H
5-Cl 2-CH3 CF3 Ph-4-OCF3 H
6-Cl 2-CH3 CF3 (L-45c)CF3 H
3-Cl-4-F 2-CH3 CF3 Ph-4-Br H
3-Cl-4-F 2-CH3 CF3 Ph-4-CF3 H
3-Cl-4-F 2-CH3 CF3 Ph-4-OCF3 H
3-Cl-4-F 2-CH3 CF3 (L-45c)CF3 H
3,4-Cl2 2-CH3 CH3 Ph-4-Br H
3,4-Cl2 2-CH3 CH3 Ph-4-CF3 H
3,4-Cl2 2-CH3 CH3 Ph-4-OCF3 H
3,4-Cl2 2-CH3 CH3 (L-45c)Cl H
3,4-Cl2 2-CH3 CH3 (L-45c)Br H
3,4-Cl2 2-CH3 CH3 (L-45c)CF3 H
3,4-Cl2 2-CH3 CH3 (L-45c)CF3 H
3,4-Cl2 2-CH3 n-Pr Ph-4-Br H
3,4-Cl2 2-CH3 i-Pr Ph-4-CF3 H
3,4-Cl2 2-CH3 c-Pr Ph-4-OCF3 H
3,4-Cl2 2-CH3 CHF2 (L-45c)CF3 H
3,4-Cl2 2-CH3 CF3 CF2O(Ph-4-Cl) H
3,4-Cl2 2-CH3 CF3 CH=CH(Ph-4-Cl) H
3,4-Cl2 2-CH3 CF3 CH=CH(Ph-4-Br) H
3,4-Cl2 2-CH3 CF3 CH=CH(Ph-4-CF3) H
3,4-Cl2 2-CH3 CF3 CH=CH(Ph-4-OCF3) H
3,4-Cl2 2-CH3 CF3 CH=CH(Ph-3,4-Cl2) H
3,4-Cl2 2-CH3 CF3 Ph-4-F H
3,4-Cl2 2-CH3 CF3 Ph-4-Cl H
3,4-Cl2 2-CH3 CF3 Ph-4-Br H
3,4-Cl2 2-CH3 CF3 Ph-4-I H
3,4-Cl2 2-CH3 CF3 Ph-4-CF3 H
3,4-Cl2 2-CH3 CF3 Ph-4-OCHF2 H
3,4-Cl2 2-CH3 CF3 Ph-4-OCF3 H
3,4-Cl2 2-CH3 CF3 Ph-4-OCF2Br H
3,4-Cl2 2-CH3 CF3 Ph-4-OCF2CHF2 H
3,4-Cl2 2-CH3 CF3 Ph-4-OCF2CHFCl H
3,4-Cl2 2-CH3 CF3 Ph-4-OCF2CHFCF3 H
3,4-Cl2 2-CH3 CF3 Ph-4-OCF2CHFOCF3 H
3,4-Cl2 2-CH3 CF3 Ph-4-OCF2CHFOCF2CF2CF3 H
3,4-Cl2 2-CH3 CF3 Ph-4-O(L-45g) H
3,4-Cl2 2-CH3 CF3 Ph-3,4-F2 H
3,4-Cl2 2-CH3 CF3 Ph-3-F-4-Cl H
3,4-Cl2 2-CH3 CF3 Ph-3,4-Cl2 H
3,4-Cl2 2-CH3 CF3 Ph(-3-OCF2O-4-) H
3,4-Cl2 2-CH3 CF3 Ph(-3-OCF2CF2O-4-) H
3,4-Cl2 2-CH3 CF3 (L-45c)Cl H
3,4-Cl2 2-CH3 CF3 (L-45c)Br H
3,4-Cl2 2-CH3 CF3 (L-45c)CF3 H
3,4-Cl2 2-CH3 CF3 L-45e H
3,4-Cl2 2-CH3 CF3 L-45f H
3,4-Cl2 2-CH3 CF3 (L-46c)Cl H
3,4-Cl2 2-CH3 CF3 (L-46c)Br H
3,4-Cl2 2-CH3 CF3 (L-46c)CF3 H
3,4-Cl2 2-CH3 CF3 L-46d H
3,4-Cl2 2-CH3 CF2Cl Ph-4-Br H
3,4-Cl2 2-CH3 CF2Br Ph-4-CF3 H
3,4-Cl2 2-CH3 CF2CF3 Ph-4-OCF3 H
3,4-Cl2 2-CH3 CF2CF2CF3 (L-45c)CF3 H
3,4-Cl2 2-CH3 CF2OCH3 Ph-4-Br H
3,4-Cl2 2-CH3 CF2SCH3 Ph-4-CF3 H
3,5-Cl2 2-CH3 CF3 Ph-4-OCF3 H
3,6-Cl2 2-CH3 CF3 (L-45c)CF3 H
5,6-Cl2 2-CH3 CF3 Ph-4-Br H
6-Br 2-CH3 CF3 Ph-4-CF3 H
3,4-Br2 2-CH3 CF3 Ph-4-OCF3 H
3,6-Br2 2-CH3 CF3 (L-45c)CF3 H
5,6-Br2 2-CH3 CF3 Ph-4-Br H
3-I 2-I CF3 Ph-4-CF3 H
3-I 2-CH3 CF3 CF2O(Ph-4-Cl) CH3
3-I 2-CH3 CF3 CF2O(Ph-4-Cl) CH2OCH3
3-I 2-CH3 CF3 CF2O(Ph-4-Cl) C(O)CH3
3-I 2-CH3 CF3 CF2O(Ph-4-Cl) Si(CH3)3
3-I 2-CH3 CF3 CH=CH(Ph-4-Cl) CH3
3-I 2-CH3 CF3 CH=CH(Ph-4-Cl) CH2OCH3
3-I 2-CH3 CF3 CH=CH(Ph-4-Cl) C(O)CH3
3-I 2-CH3 CF3 CH=CH(Ph-4-Cl) Si(CH3)3
3-I 2-CH3 CF3 CH=CH(Ph-4-Br) CH3
3-I 2-CH3 CF3 CH=CH(Ph-4-Br) CH2OCH3
3-I 2-CH3 CF3 CH=CH(Ph-4-Br) C(O)CH3
3-I 2-CH3 CF3 CH=CH(Ph-4-Br) Si(CH3)3
3-I 2-CH3 CF3 CH=CH(Ph-4-CF3) CH3
3-I 2-CH3 CF3 CH=CH(Ph-4-CF3) CH2OCH3
3-I 2-CH3 CF3 CH=CH(Ph-4-CF3) C(O)CH3
3-I 2-CH3 CF3 CH=CH(Ph-4-CF3) Si(CH3)3
3-I 2-CH3 CF3 CH=CH(Ph-4-OCF3) CH3
3-I 2-CH3 CF3 CH=CH(Ph-4-OCF3) CH2OCH3
3-I 2-CH3 CF3 CH=CH(Ph-4-OCF3) C(O)CH3
3-I 2-CH3 CF3 CH=CH(Ph-4-OCF3) Si(CH3)3
3-I 2-CH3 CF3 CH=CH(Ph-3,4-Cl2) CH3
3-I 2-CH3 CF3 CH=CH(Ph-3,4-Cl2) CH2OCH3
3-I 2-CH3 CF3 CH=CH(Ph-3,4-Cl2) C(O)CH3
3-I 2-CH3 CF3 CH=CH(Ph-3,4-Cl2) Si(CH3)3
3-I 2-CH3 CF3 Ph-4-F CH3
3-I 2-CH3 CF3 Ph-4-F CH2OCH3
3-I 2-CH3 CF3 Ph-4-F C(O)CH3
3-I 2-CH3 CF3 Ph-4-F Si(CH3)3
3-I 2-CH3 CF3 Ph-4-Cl CH3
3-I 2-CH3 CF3 Ph-4-Cl CH2OCH3
3-I 2-CH3 CF3 Ph-4-Cl C(O)CH3
3-I 2-CH3 CF3 Ph-4-Cl Si(CH3)3
3-I 2-CH3 CF3 Ph-4-Br CH3
3-I 2-CH3 CF3 Ph-4-Br Et
3-I 2-CH3 CF3 Ph-4-Br n-Pr
3-I 2-CH3 CF3 Ph-4-Br i-Pr
3-I 2-CH3 CF3 Ph-4-Br n-Bu
3-I 2-CH3 CF3 Ph-4-Br CH2CF3
3-I 2-CH3 CF3 Ph-4-Br CH2OCH3
3-I 2-CH3 CF3 Ph-4-Br CH2OEt
3-I 2-CH3 CF3 Ph-4-Br CH2SCH3
3-I 2-CH3 CF3 Ph-4-Br CH2CH=CH2
3-I 2-CH3 CF3 Ph-4-Br CH2CH=CF2
3-I 2-CH3 CF3 Ph-4-Br CH2CH=CCl2
3-I 2-CH3 CF3 Ph-4-Br CH2CF=CF2
3-I 2-CH3 CF3 Ph-4-Br CH2CCl=CCl2
3-I 2-CH3 CF3 Ph-4-Br CH2C≡CH
3-I 2-CH3 CF3 Ph-4-Br CH2Ph
3-I 2-CH3 CF3 Ph-4-Br C(O)CH3
3-I 2-CH3 CF3 Ph-4-Br C(O)Bu-t
3-I 2-CH3 CF3 Ph-4-Br C(O)SCH3
3-I 2-CH3 CF3 Ph-4-Br C(S)SEt
3-I 2-CH3 CF3 Ph-4-Br Si(CH3)3
3-I 2-CH3 CF3 Ph-4-Br Si(CH3)2Bu-t
3-I 2-CH3 CF3 Ph-4-Br Si(CH3)2Ph
3-I 2-CH3 CF3 Ph-4-I CH3
3-I 2-CH3 CF3 Ph-4-I CH2OCH3
3-I 2-CH3 CF3 Ph-4-I C(O)CH3
3-I 2-CH3 CF3 Ph-4-I Si(CH3)3
3-I 2-CH3 CF3 Ph-4-CF3 CH3
3-I 2-CH3 CF3 Ph-4-CF3 Et
3-I 2-CH3 CF3 Ph-4-CF3 n-Pr
3-I 2-CH3 CF3 Ph-4-CF3 i-Pr
3-I 2-CH3 CF3 Ph-4-CF3 n-Bu
3-I 2-CH3 CF3 Ph-4-CF3 CH2CF3
3-I 2-CH3 CF3 Ph-4-CF3 CH2OCH3
3-I 2-CH3 CF3 Ph-4-CF3 CH2OEt
3-I 2-CH3 CF3 Ph-4-CF3 CH2SCH3
3-I 2-CH3 CF3 Ph-4-CF3 CH2CH=CH2
3-I 2-CH3 CF3 Ph-4-CF3 CH2CH=CF2
3-I 2-CH3 CF3 Ph-4-CF3 CH2CH=CCl2
3-I 2-CH3 CF3 Ph-4-CF3 CH2CF=CF2
3-I 2-CH3 CF3 Ph-4-CF3 CH2CCl=CCl2
3-I 2-CH3 CF3 Ph-4-CF3 CH2C≡CH
3-I 2-CH3 CF3 Ph-4-CF3 CH2Ph
3-I 2-CH3 CF3 Ph-4-CF3 C(O)CH3
3-I 2-CH3 CF3 Ph-4-CF3 C(O)Bu-t
3-I 2-CH3 CF3 Ph-4-CF3 C(O)SCH3
3-I 2-CH3 CF3 Ph-4-CF3 C(S)SEt
3-I 2-CH3 CF3 Ph-4-CF3 Si(CH3)3
3-I 2-CH3 CF3 Ph-4-CF3 Si(CH3)2Bu-t
3-I 2-CH3 CF3 Ph-4-CF3 Si(CH3)2Ph
3-I 2-CH3 CF3 Ph-4-CHF2 CH3
3-I 2-CH3 CF3 Ph-4-CHF2 CH2OCH3
3-I 2-CH3 CF3 Ph-4-CHF2 C(O)CH3
3-I 2-CH3 CF3 Ph-4-CHF2 Si(CH3)3
3-I 2-CH3 CF3 Ph-4-OCF3 CH3
3-I 2-CH3 CF3 Ph-4-OCF3 Et
3-I 2-CH3 CF3 Ph-4-OCF3 n-Pr
3-I 2-CH3 CF3 Ph-4-OCF3 i-Pr
3-I 2-CH3 CF3 Ph-4-OCF3 n-Bu
3-I 2-CH3 CF3 Ph-4-OCF3 CH2CF3
3-I 2-CH3 CF3 Ph-4-OCF3 CH2OCH3
3-I 2-CH3 CF3 Ph-4-OCF3 CH2OEt
3-I 2-CH3 CF3 Ph-4-OCF3 CH2SCH3
3-I 2-CH3 CF3 Ph-4-OCF3 CH2CH=CH2
3-I 2-CH3 CF3 Ph-4-OCF3 CH2CH=CF2
3-I 2-CH3 CF3 Ph-4-OCF3 CH2CH=CCl2
3-I 2-CH3 CF3 Ph-4-OCF3 CH2CF=CF2
3-I 2-CH3 CF3 Ph-4-OCF3 CH2CCl=CCl2
3-I 2-CH3 CF3 Ph-4-OCF3 CH2C≡CH
3-I 2-CH3 CF3 Ph-4-OCF3 CH2Ph
3-I 2-CH3 CF3 Ph-4-OCF3 C(O)CH3
3-I 2-CH3 CF3 Ph-4-OCF3 C(O)Bu-t
3-I 2-CH3 CF3 Ph-4-OCF3 C(O)SCH3
3-I 2-CH3 CF3 Ph-4-OCF3 C(S)SEt
3-I 2-CH3 CF3 Ph-4-OCF3 Si(CH3)3
3-I 2-CH3 CF3 Ph-4-OCF3 Si(CH3)2Bu-t
3-I 2-CH3 CF3 Ph-4-OCF3 Si(CH3)2Ph
3-I 2-CH3 CF3 Ph-4-OCF2Br CH3
3-I 2-CH3 CF3 Ph-4-OCF2Br CH2OCH3
3-I 2-CH3 CF3 Ph-4-OCF2Br C(O)CH3
3-I 2-CH3 CF3 Ph-4-OCF2Br Si(CH3)3
3-I 2-CH3 CF3 Ph-4-OCF2CHF2 CH3
3-I 2-CH3 CF3 Ph-4-OCF2CHF2 CH2OCH3
3-I 2-CH3 CF3 Ph-4-OCF2CHF2 C(O)CH3
3-I 2-CH3 CF3 Ph-4-OCF2CHF2 Si(CH3)3
3-I 2-CH3 CF3 Ph-4-OCF2CHFCl CH3
3-I 2-CH3 CF3 Ph-4-OCF2CHFCl CH2OCH3
3-I 2-CH3 CF3 Ph-4-OCF2CHFCl C(O)CH3
3-I 2-CH3 CF3 Ph-4-OCF2CHFCl Si(CH3)3
3-I 2-CH3 CF3 Ph-4-OCF2CHFCF3 CH3
3-I 2-CH3 CF3 Ph-4-OCF2CHFCF3 CH2OCH3
3-I 2-CH3 CF3 Ph-4-OCF2CHFCF3 C(O)CH3
3-I 2-CH3 CF3 Ph-4-OCF2CHFCF3 Si(CH3)3
3-I 2-CH3 CF3 Ph-4-OCF2CHFOCF3 CH3
3-I 2-CH3 CF3 Ph-4-OCF2CHFOCF3 CH2OCH3
3-I 2-CH3 CF3 Ph-4-OCF2CHFOCF3 C(O)CH3
3-I 2-CH3 CF3 Ph-4-OCF2CHFOCF3 Si(CH3)3
3-I 2-CH3 CF3 Ph-4-OCF2CHFOCF2CF2CF3 CH3
3-I 2-CH3 CF3 Ph-4-OCF2CHFOCF2CF2CF3 CH2OCH3
3-I 2-CH3 CF3 Ph-4-OCF2CHFOCF2CF2CF3 C(O)CH3
3-I 2-CH3 CF3 Ph-4-OCF2CHFOCF2CF2CF3 Si(CH3)3
3-I 2-CH3 CF3 Ph-4-O(L-45g) CH3
3-I 2-CH3 CF3 Ph-4-O(L-45g) CH2OCH3
3-I 2-CH3 CF3 Ph-4-O(L-45g) C(O)CH3
3-I 2-CH3 CF3 Ph-4-O(L-45g) Si(CH3)3
3-I 2-CH3 CF3 Ph-3,4-F2 CH3
3-I 2-CH3 CF3 Ph-3,4-F2 CH2OCH3
3-I 2-CH3 CF3 Ph-3,4-F2 C(O)CH3
3-I 2-CH3 CF3 Ph-3,4-F2 Si(CH3)3
3-I 2-CH3 CF3 Ph-3-F-4-Cl CH3
3-I 2-CH3 CF3 Ph-3-F-4-Cl CH2OCH3
3-I 2-CH3 CF3 Ph-3-F-4-Cl C(O)CH3
3-I 2-CH3 CF3 Ph-3-F-4-Cl Si(CH3)3
3-I 2-CH3 CF3 Ph-3,4-Cl2 CH3
3-I 2-CH3 CF3 Ph-3,4-Cl2 CH2OCH3
3-I 2-CH3 CF3 Ph-3,4-Cl2 C(O)CH3
3-I 2-CH3 CF3 Ph-3,4-Cl2 Si(CH3)3
3-I 2-CH3 CF3 Ph(-3-OCF2O-4-) CH3
3-I 2-CH3 CF3 Ph(-3-OCF2O-4-) CH2OCH3
3-I 2-CH3 CF3 Ph(-3-OCF2O-4-) C(O)CH3
3-I 2-CH3 CF3 Ph(-3-OCF2O-4-) Si(CH3)3
3-I 2-CH3 CF3 Ph(-3-OCF2CF2O-4-) CH3
3-I 2-CH3 CF3 Ph(-3-OCF2CF2O-4-) CH2OCH3
3-I 2-CH3 CF3 Ph(-3-OCF2CF2O-4-) C(O)CH3
3-I 2-CH3 CF3 Ph(-3-OCF2CF2O-4-) Si(CH3)3
3-I 2-CH3 CF3 (L-45c)Cl CH3
3-I 2-CH3 CF3 (L-45c)Cl CH2OCH3
3-I 2-CH3 CF3 (L-45c)Cl C(O)CH3
3-I 2-CH3 CF3 (L-45c)Cl Si(CH3)3
3-I 2-CH3 CF3 (L-45c)Br CH3
3-I 2-CH3 CF3 (L-45c)Br CH2OCH3
3-I 2-CH3 CF3 (L-45c)Br C(O)CH3
3-I 2-CH3 CF3 (L-45c)Br Si(CH3)3
3-I 2-CH3 CF3 (L-45c)CF3 CH3
3-I 2-CH3 CF3 (L-45c)CF3 Et
3-I 2-CH3 CF3 (L-45c)CF3 n-Pr
3-I 2-CH3 CF3 (L-45c)CF3 i-Pr
3-I 2-CH3 CF3 (L-45c)CF3 n-Bu
3-I 2-CH3 CF3 (L-45c)CF3 CH2CF3
3-I 2-CH3 CF3 (L-45c)CF3 CH2OCH3
3-I 2-CH3 CF3 (L-45c)CF3 CH2OEt
3-I 2-CH3 CF3 (L-45c)CF3 CH2SCH3
3-I 2-CH3 CF3 (L-45c)CF3 CH2CH=CH2
3-I 2-CH3 CF3 (L-45c)CF3 CH2CH=CF2
3-I 2-CH3 CF3 (L-45c)CF3 CH2CH=CCl2
3-I 2-CH3 CF3 (L-45c)CF3 CH2CF=CF2
3-I 2-CH3 CF3 (L-45c)CF3 CH2CCl=CCl2
3-I 2-CH3 CF3 (L-45c)CF3 CH2C≡CH
3-I 2-CH3 CF3 (L-45c)CF3 CH2Ph
3-I 2-CH3 CF3 (L-45c)CF3 C(O)CH3
3-I 2-CH3 CF3 (L-45c)CF3 C(O)Bu-t
3-I 2-CH3 CF3 (L-45c)CF3 C(O)SCH3
3-I 2-CH3 CF3 (L-45c)CF3 C(S)SEt
3-I 2-CH3 CF3 (L-45c)CF3 Si(CH3)3
3-I 2-CH3 CF3 (L-45c)CF3 Si(CH3)2Bu-t
3-I 2-CH3 CF3 (L-45c)CF3 Si(CH3)2Ph
3-I 2-CH3 CF3 L-45e CH3
3-I 2-CH3 CF3 L-45e CH2OCH3
3-I 2-CH3 CF3 L-45e C(O)CH3
3-I 2-CH3 CF3 L-45e Si(CH3)3
3-I 2-CH3 CF3 L-45f CH3
3-I 2-CH3 CF3 L-45f CH2OCH3
3-I 2-CH3 CF3 L-45f C(O)CH3
3-I 2-CH3 CF3 L-45f Si(CH3)3
3-I 2-CH3 CF3 (L-46c)Cl CH3
3-I 2-CH3 CF3 (L-46c)Cl CH2OCH3
3-I 2-CH3 CF3 (L-46c)Cl C(O)CH3
3-I 2-CH3 CF3 (L-46c)Cl Si(CH3)3
3-I 2-CH3 CF3 (L-46c)Br CH3
3-I 2-CH3 CF3 (L-46c)Br CH2OCH3
3-I 2-CH3 CF3 (L-46c)Br C(O)CH3
3-I 2-CH3 CF3 (L-46c)Br Si(CH3)3
3-I 2-CH3 CF3 (L-46c)CF3 CH3
3-I 2-CH3 CF3 (L-46c)CF3 CH2OCH3
3-I 2-CH3 CF3 (L-46c)CF3 C(O)CH3
3-I 2-CH3 CF3 (L-46c)CF3 Si(CH3)3
3-I 2-CH3 CF3 L-46d CH3
3-I 2-CH3 CF3 L-46d CH2OCH3
3-I 2-CH3 CF3 L-46d C(O)CH3
3-I 2-CH3 CF3 L-46d Si(CH3)3
3-I 2-Pr-n CF3 Ph-4-OCF3 H
3-I 2-Pr-i CF3 (L-45c)CF3 H
3-I 2-Bu-n CF3 Ph-4-Br H
3-I 2-CF3 CF3 Ph-4-CF3 H
3-I 2-CF2CF3 CF3 Ph-4-OCF3 H
3-I 2-CH2OH CF3 Ph-4-Br H
3-I 2-CH2OH CF3 Ph-4-CF3 H
3-I 2-CH2OH CF3 Ph-4-OCF3 H
3-I 2-CH2OH CF3 (L-45c)CF3 H
3-I 2-CH2OCH3 CF3 (L-45c)CF3 H
3-I 2-CH2SCH3 CF3 Ph-4-Br H
3-I 2-OCH3 CF3 Ph-4-Br H
3-I 2-OCH3 CF3 Ph-4-CF3 H
3-I 2-OCH3 CF3 Ph-4-OCF3 H
3-I 2-OCH3 CF3 (L-45c)CF3 H
3-I 2-OEt CF3 Ph-4-CF3 H
3-I 2-OPr-i CF3 Ph-4-OCF3 H
3-I 2-OCF3 CF3 (L-45c)CF3 H
3-I 2-OPh CF3 Ph-4-Br H
3-I 2-SCH3 CF3 Ph-4-Br H
3-I 2-SCH3 CF3 Ph-4-CF3 H
3-I 2-SCH3 CF3 Ph-4-OCF3 H
3-I 2-SCH3 CF3 (L-45c)CF3 H
3-I 2-SO2CH3 CF3 Ph-4-CF3 H
3-I 2-SEt CF3 Ph-4-OCF3 H
3-I 2-SPr-i CF3 (L-45c)CF3 H
3-I 2-SCHF2 CF3 Ph-4-Br H
3-I 2-N(CH3)2 CF3 Ph-4-CF3 H
3-I 2-CN CF3 Ph-4-OCF3 H
3-I 2-Ph CF3 (L-45c)CF3 H
3-I 2-(L-14a) CF3 Ph-4-Br H
3-I 2-(L-14b) CF3 Ph-4-CF3 H
3-I 2-(L-14c) CF3 Ph-4-OCF3 H
3-I 2-(L-14d) CF3 (L-45c)CF3 H
3-I 2-(L-14e) CF3 Ph-4-Br H
3-I 2-(L-14f) CF3 Ph-4-CF3 H
3-I 2-CH3-3-F CF3 Ph-4-OCF3 H
3-I 2-CH3-5-F CF3 (L-45c)CF3 H
3-I 2-CH3-3-Cl CF3 Ph-4-Br H
3-I 2-CH3-5-Cl CF3 Ph-4-CF3 H
3-I 2,3-(CH3)2 CF3 Ph-4-OCF3 H
3-I 2,5-(CH3)2 CF3 (L-45c)CF3 H
3-I 2,6-(CH3)2 CF3 Ph-4-Br H
3-I 2-CH3-3-OCH3 CF3 Ph-4-CF3 H
3-I 2-CH3-3-OCHF2 CF3 Ph-4-OCF3 H
3-I 2-CH3-3,5-Cl2 CF3 (L-45c)CF3 H
4-I 2-CH3 CF3 Ph-4-Br H
5-I 2-CH3 CF3 Ph-4-CF3 H
6-I 2-CH3 CF3 Ph-4-OCF3 H
3-I-4-Cl 2-CH3 CF3 (L-45c)CF3 H
4-Cl-6-I 2-CH3 CF3 Ph-4-Br H
5-CH3 2-CH3 CF3 Ph-4-CF3 H
6-CH3 2-CH3 CF3 Ph-4-OCF3 H
3-Cl-4-CH3 2-CH3 CF3 Ph-4-Br H
3-Cl-4-CH3 2-CH3 CF3 Ph-4-CF3 H
3-Cl-4-CH3 2-CH3 CF3 Ph-4-OCF3 H
3-Cl-4-CH3 2-CH3 CF3 (L-45c)CF3 H
6-Et 2-CH3 CF3 (L-45c)CF3 H
4-CF3 2-CH3 CF3 Ph-4-Br H
6-CF3 2-CH3 CF3 Ph-4-CF3 H
3-CF2CF3 2-CH3 CF3 Ph-4-OCF3 H
3-OCH3 2-CH3 CF3 (L-45c)CF3 H
6-OCH3 2-CH3 CF3 Ph-4-Br H
3-Cl-4-OCH3 2-CH3 CF3 Ph-4-CF3 H
3-OCH2O-4 2-CH3 CF3 Ph-4-OCF3 H
5-OCHF2 2-CH3 CF3 (L-45c)CF3 H
6-OCHF2 2-CH3 CF3 Ph-4-Br H
5-OCF3 2-CH3 CF3 Ph-4-CF3 H
3-OSO2CH3 2-CH3 CF3 CF2O(Ph-4-Cl) H
3-OSO2CH3 2-CH3 CF3 CH=CH(Ph-4-Cl) H
3-OSO2CH3 2-CH3 CF3 CH=CH(Ph-4-Br) H
3-OSO2CH3 2-CH3 CF3 CH=CH(Ph-4-CF3) H
3-OSO2CH3 2-CH3 CF3 CH=CH(Ph-4-OCF3) H
3-OSO2CH3 2-CH3 CF3 CH=CH(Ph-3,4-Cl2) H
3-OSO2CH3 2-CH3 CF3 Ph-4-F H
3-OSO2CH3 2-CH3 CF3 Ph-4-Cl H
3-OSO2CH3 2-CH3 CF3 Ph-4-Br H
3-OSO2CH3 2-CH3 CF3 Ph-4-CF3 H
3-OSO2CH3 2-CH3 CF3 Ph-4-OCF3 H
3-OSO2CH3 2-CH3 CF3 Ph-4-OCF2Br H
3-OSO2CH3 2-CH3 CF3 Ph-4-OCF2CHF2 H
3-OSO2CH3 2-CH3 CF3 Ph-4-OCF2CHFCF3 H
3-OSO2CH3 2-CH3 CF3 Ph-4-OCF2CHFOCF3 H
3-OSO2CH3 2-CH3 CF3 Ph-4-OCF2CHFOCF2CF2CF3 H
3-OSO2CH3 2-CH3 CF3 Ph-4-O(L-45g) H
3-OSO2CH3 2-CH3 CF3 Ph-3,4-F2 H
3-OSO2CH3 2-CH3 CF3 Ph-3-F-4-Cl H
3-OSO2CH3 2-CH3 CF3 Ph-3,4-Cl2 H
3-OSO2CH3 2-CH3 CF3 Ph(-3-OCF2O-4-) H
3-OSO2CH3 2-CH3 CF3 Ph(-3-OCF2CF2O-4-) H
3-OSO2CH3 2-CH3 CF3 (L-45c)CF3 H
3-OSO2CH3 2-CH3 CF3 L-45f H
3-OSO2CH3 2-CH3 CF3 (L-46c)CF3 H
3-OSO2CH3 2-CH3 CF3 L-46d H
3-OSO2Et 2-CH3 CF3 Ph-4-OCF3 H
3-OSO2CF3 2-CH3 CF3 (L-45c)CF3 H
3-OCF2O-4 2-CH3 CF3 CF2O(Ph-4-Cl) H
3-OCF2O-4 2-CH3 CF3 CH=CH(Ph-4-Cl) H
3-OCF2O-4 2-CH3 CF3 CH=CH(Ph-4-Br) H
3-OCF2O-4 2-CH3 CF3 CH=CH(Ph-4-CF3) H
3-OCF2O-4 2-CH3 CF3 CH=CH(Ph-4-OCF3) H
3-OCF2O-4 2-CH3 CF3 CH=CH(Ph-3,4-Cl2) H
3-OCF2O-4 2-CH3 CF3 Ph-4-F H
3-OCF2O-4 2-CH3 CF3 Ph-4-Cl H
3-OCF2O-4 2-CH3 CF3 Ph-4-Br H
3-OCF2O-4 2-CH3 CF3 Ph-4-CF3 H
3-OCF2O-4 2-CH3 CF3 Ph-4-OCF3 H
3-OCF2O-4 2-CH3 CF3 Ph-4-OCF2Br H
3-OCF2O-4 2-CH3 CF3 Ph-4-OCF2CHF2 H
3-OCF2O-4 2-CH3 CF3 Ph-4-OCF2CHFCF3 H
3-OCF2O-4 2-CH3 CF3 Ph-4-OCF2CHFOCF3 H
3-OCF2O-4 2-CH3 CF3 Ph-4-OCF2CHFOCF2CF2CF3 H
3-OCF2O-4 2-CH3 CF3 Ph-4-O(L-45g) H
3-OCF2O-4 2-CH3 CF3 Ph-3,4-F2 H
3-OCF2O-4 2-CH3 CF3 Ph-3-F-4-Cl H
3-OCF2O-4 2-CH3 CF3 Ph-3,4-Cl2 H
3-OCF2O-4 2-CH3 CF3 Ph(-3-OCF2O-4-) H
3-OCF2O-4 2-CH3 CF3 Ph(-3-OCF2CF2O-4-) H
3-OCF2O-4 2-CH3 CF3 (L-45c)CF3 H
3-OCF2O-4 2-CH3 CF3 L-45f H
3-OCF2O-4 2-CH3 CF3 (L-46c)CF3 H
3-OCF2O-4 2-CH3 CF3 L-46d H
3-OCF2CF2O-4 2-CH3 CF3 CH=CH(Ph-4-Cl) H
3-OCF2CF2O-4 2-CH3 CF3 Ph-4-Cl H
3-OCF2CF2O-4 2-CH3 CF3 Ph-4-Br H
3-OCF2CF2O-4 2-CH3 CF3 Ph-4-CF3 H
3-OCF2CF2O-4 2-CH3 CF3 Ph-4-OCF3 H
3-OCF2CF2O-4 2-CH3 CF3 Ph-4-OCF2Br H
3-OCF2CF2O-4 2-CH3 CF3 Ph-4-OCF2CHFCF3 H
3-OCF2CF2O-4 2-CH3 CF3 Ph-4-OCF2CHFOCF3 H
3-OCF2CF2O-4 2-CH3 CF3 Ph-4-OCF2CHFOCF2CF2CF3 H
3-OCF2CF2O-4 2-CH3 CF3 Ph-4-O(L-45g) H
3-OCF2CF2O-4 2-CH3 CF3 Ph-3,4-Cl2 H
3-OCF2CF2O-4 2-CH3 CF3 Ph(-3-OCF2O-4-) H
3-OCF2CF2O-4 2-CH3 CF3 Ph(-3-OCF2CF2O-4-) H
3-OCF2CF2O-4 2-CH3 CF3 (L-45c)CF3 H
3-OCF2CF2O-4 2-CH3 CF3 L-45f H
3-OCF2CF2O-4 2-CH3 CF3 (L-46c)CF3 H
3-OCF2CF2O-4 2-CH3 CF3 L-46d H
6-SCH3 2-CH3 CF3 Ph-4-Br H
6-SO2CH3 2-CH3 CF3 Ph-4-CF3 H
3-SEt 2-CH3 CF3 Ph-4-OCF3 H
3-SO2Et 2-CH3 CF3 (L-45c)CF3 H
3-SPr-i 2-CH3 CF3 Ph-4-Br H
3-S(O)Pr-i 2-CH3 CF3 Ph-4-CF3 H
3-SO2Pr-i 2-CH3 CF3 Ph-4-OCF3 H
6-S(O)CF3 2-CH3 CF3 (L-45c)CF3 H
3-SCH2CF3 2-CH3 CF3 Ph-4-Br H
6-SCH2CF3 2-CH3 CF3 Ph-4-CF3 H
3-S(O)CH2CF3 2-CH3 CF3 Ph-4-OCF3 H
6-S(O)CH2CF3 2-CH3 CF3 (L-45c)CF3 H
3-SO2CH2CF3 2-CH3 CF3 Ph-4-Br H
3-Cl-6-SCF3 2-CH3 CF3 Ph-4-CF3 H
6-NO2 2-CH3 CF3 Ph-4-OCF3 H
3-CN 2-CH3 CF3 (L-45c)CF3 H
6-C(O)OCH3 2-CH3 CF3 Ph-4-Br H
3-C(O)NHPr-i 2-CH3 CF3 Ph-4-CF3 H
3-C≡CH 2-CH3 CF3 Ph-4-OCF3 H
3-C≡CSi(CH3)3 2-CH3 CF3 (L-45c)CF3 H
6-C≡CH 2-CH3 CF3 Ph-4-Br H
6-Ph 2-CH3 CF3 Ph-4-CF3 H
3-CH=CH-CH=CH-4 2-CH3 CF3 Ph-4-OCF3 H
4-CH=CH-CH=CH-5 2-CH3 CF3 (L-45c)CF3 H
3-Si(CH3)3 2-CH3 CF3 Ph-4-Br H
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第４表
表中、置換基(X)mの置換位置を表す番号は、それぞれ下記の構造式に於いて記された番号の位置に対応するものであり、−の表記は、無置換を表す。 ―――――――――――――――――――――――――――――――――――――――
(X) m (Y) n R 4 R 5 R 6
―――――――――――――――――――――――――――――――――――――――
− 2-CH 3 CF 3 Ph-4-Br H
5-F 2-CH 3 CF 3 Ph-4-CF 3 H
6-F 2-CH 3 CF 3 Ph-4-OCF 3 H
3,4-F 2 2-CH 3 CF 3 Ph-4-Br H
3,4-F 2 2-CH 3 CF 3 Ph-4-CF 3 H
3,4-F 2 2-CH 3 CF 3 Ph-4-OCF 3 H
3,4-F 2 2-CH 3 CF 3 (L-45c) CF 3 H
3,6-F 2 2-CH 3 CF 3 (L-45c) CF 3 H
4,5-F 2 2-CH 3 CF 3 Ph-4-Br H
4-Cl 2-CH 3 CF 3 Ph-4-CF 3 H
5-Cl 2-CH 3 CF 3 Ph-4-OCF 3 H
6-Cl 2-CH 3 CF 3 (L-45c) CF 3 H
3-Cl-4-F 2-CH 3 CF 3 Ph-4-Br H
3-Cl-4-F 2-CH 3 CF 3 Ph-4-CF 3 H
3-Cl-4-F 2-CH 3 CF 3 Ph-4-OCF 3 H
3-Cl-4-F 2-CH 3 CF 3 (L-45c) CF 3 H
3,4-Cl 2 2-CH 3 CH 3 Ph-4-Br H
3,4-Cl 2 2-CH 3 CH 3 Ph-4-CF 3 H
3,4-Cl 2 2-CH 3 CH 3 Ph-4-OCF 3 H
3,4-Cl 2 2-CH 3 CH 3 (L-45c) Cl H
3,4-Cl 2 2-CH 3 CH 3 (L-45c) Br H
3,4-Cl 2 2-CH 3 CH 3 (L-45c) CF 3 H
3,4-Cl 2 2-CH 3 CH 3 (L-45c) CF 3 H
3,4-Cl 2 2-CH 3 n-Pr Ph-4-Br H
3,4-Cl 2 2-CH 3 i-Pr Ph-4-CF 3 H
3,4-Cl 2 2-CH 3 c-Pr Ph-4-OCF 3 H
3,4-Cl 2 2-CH 3 CHF 2 (L-45c) CF 3 H
3,4-Cl 2 2-CH 3 CF 3 CF 2 O (Ph-4-Cl) H
3,4-Cl 2 2-CH 3 CF 3 CH = CH (Ph-4-Cl) H
3,4-Cl 2 2-CH 3 CF 3 CH = CH (Ph-4-Br) H
3,4-Cl 2 2-CH 3 CF 3 CH = CH (Ph-4-CF 3 ) H
3,4-Cl 2 2-CH 3 CF 3 CH = CH (Ph-4-OCF 3 ) H
3,4-Cl 2 2-CH 3 CF 3 CH = CH (Ph-3,4-Cl 2 ) H
3,4-Cl 2 2-CH 3 CF 3 Ph-4-FH
3,4-Cl 2 2-CH 3 CF 3 Ph-4-Cl H
3,4-Cl 2 2-CH 3 CF 3 Ph-4-Br H
3,4-Cl 2 2-CH 3 CF 3 Ph-4-IH
3,4-Cl 2 2-CH 3 CF 3 Ph-4-CF 3 H
3,4-Cl 2 2-CH 3 CF 3 Ph-4-OCHF 2 H
3,4-Cl 2 2-CH 3 CF 3 Ph-4-OCF 3 H
3,4-Cl 2 2-CH 3 CF 3 Ph-4-OCF 2 Br H
3,4-Cl 2 2-CH 3 CF 3 Ph-4-OCF 2 CHF 2 H
3,4-Cl 2 2-CH 3 CF 3 Ph-4-OCF 2 CHFCl H
3,4-Cl 2 2-CH 3 CF 3 Ph-4-OCF 2 CHFCF 3 H
3,4-Cl 2 2-CH 3 CF 3 Ph-4-OCF 2 CHFOCF 3 H
3,4-Cl 2 2-CH 3 CF 3 Ph-4-OCF 2 CHFOCF 2 CF 2 CF 3 H
3,4-Cl 2 2-CH 3 CF 3 Ph-4-O (L-45g) H
3,4-Cl 2 2-CH 3 CF 3 Ph-3,4-F 2 H
3,4-Cl 2 2-CH 3 CF 3 Ph-3-F-4-Cl H
3,4-Cl 2 2-CH 3 CF 3 Ph-3,4-Cl 2 H
3,4-Cl 2 2-CH 3 CF 3 Ph (-3-OCF 2 O-4-) H
3,4-Cl 2 2-CH 3 CF 3 Ph (-3-OCF 2 CF 2 O-4-) H
3,4-Cl 2 2-CH 3 CF 3 (L-45c) Cl H
3,4-Cl 2 2-CH 3 CF 3 (L-45c) Br H
3,4-Cl 2 2-CH 3 CF 3 (L-45c) CF 3 H
3,4-Cl 2 2-CH 3 CF 3 L-45e H
3,4-Cl 2 2-CH 3 CF 3 L-45f H
3,4-Cl 2 2-CH 3 CF 3 (L-46c) Cl H
3,4-Cl 2 2-CH 3 CF 3 (L-46c) Br H
3,4-Cl 2 2-CH 3 CF 3 (L-46c) CF 3 H
3,4-Cl 2 2-CH 3 CF 3 L-46d H
3,4-Cl 2 2-CH 3 CF 2 Cl Ph-4-Br H
3,4-Cl 2 2-CH 3 CF 2 Br Ph-4-CF 3 H
3,4-Cl 2 2-CH 3 CF 2 CF 3 Ph-4-OCF 3 H
3,4-Cl 2 2-CH 3 CF 2 CF 2 CF 3 (L-45c) CF 3 H
3,4-Cl 2 2-CH 3 CF 2 OCH 3 Ph-4-Br H
3,4-Cl 2 2-CH 3 CF 2 SCH 3 Ph-4-CF 3 H
3,5-Cl 2 2-CH 3 CF 3 Ph-4-OCF 3 H
3,6-Cl 2 2-CH 3 CF 3 (L-45c) CF 3 H
5,6-Cl 2 2-CH 3 CF 3 Ph-4-Br H
6-Br 2-CH 3 CF 3 Ph-4-CF 3 H
3,4-Br 2 2-CH 3 CF 3 Ph-4-OCF 3 H
3,6-Br 2 2-CH 3 CF 3 (L-45c) CF 3 H
5,6-Br 2 2-CH 3 CF 3 Ph-4-Br H
3-I 2-I CF 3 Ph-4-CF 3 H
3-I 2-CH 3 CF 3 CF 2 O (Ph-4-Cl) CH 3
3-I 2-CH 3 CF 3 CF 2 O (Ph-4-Cl) CH 2 OCH 3
3-I 2-CH 3 CF 3 CF 2 O (Ph-4-Cl) C (O) CH 3
3-I 2-CH 3 CF 3 CF 2 O (Ph-4-Cl) Si (CH 3 ) 3
3-I 2-CH 3 CF 3 CH = CH (Ph-4-Cl) CH 3
3-I 2-CH 3 CF 3 CH = CH (Ph-4-Cl) CH 2 OCH 3
3-I 2-CH 3 CF 3 CH = CH (Ph-4-Cl) C (O) CH 3
3-I 2-CH 3 CF 3 CH = CH (Ph-4-Cl) Si (CH 3 ) 3
3-I 2-CH 3 CF 3 CH = CH (Ph-4-Br) CH 3
3-I 2-CH 3 CF 3 CH = CH (Ph-4-Br) CH 2 OCH 3
3-I 2-CH 3 CF 3 CH = CH (Ph-4-Br) C (O) CH 3
3-I 2-CH 3 CF 3 CH = CH (Ph-4-Br) Si (CH 3 ) 3
3-I 2-CH 3 CF 3 CH = CH (Ph-4-CF 3 ) CH 3
3-I 2-CH 3 CF 3 CH = CH (Ph-4-CF 3 ) CH 2 OCH 3
3-I 2-CH 3 CF 3 CH = CH (Ph-4-CF 3 ) C (O) CH 3
3-I 2-CH 3 CF 3 CH = CH (Ph-4-CF 3 ) Si (CH 3 ) 3
3-I 2-CH 3 CF 3 CH = CH (Ph-4-OCF 3 ) CH 3
3-I 2-CH 3 CF 3 CH = CH (Ph-4-OCF 3 ) CH 2 OCH 3
3-I 2-CH 3 CF 3 CH = CH (Ph-4-OCF 3 ) C (O) CH 3
3-I 2-CH 3 CF 3 CH = CH (Ph-4-OCF 3 ) Si (CH 3 ) 3
3-I 2-CH 3 CF 3 CH = CH (Ph-3,4-Cl 2 ) CH 3
3-I 2-CH 3 CF 3 CH = CH (Ph-3,4-Cl 2 ) CH 2 OCH 3
3-I 2-CH 3 CF 3 CH = CH (Ph-3,4-Cl 2 ) C (O) CH 3
3-I 2-CH 3 CF 3 CH = CH (Ph-3,4-Cl 2 ) Si (CH 3 ) 3
3-I 2-CH 3 CF 3 Ph-4-F CH 3
3-I 2-CH 3 CF 3 Ph-4-F CH 2 OCH 3
3-I 2-CH 3 CF 3 Ph-4-FC (O) CH 3
3-I 2-CH 3 CF 3 Ph-4-F Si (CH 3 ) 3
3-I 2-CH 3 CF 3 Ph-4-Cl CH 3
3-I 2-CH 3 CF 3 Ph-4-Cl CH 2 OCH 3
3-I 2-CH 3 CF 3 Ph-4-Cl C (O) CH 3
3-I 2-CH 3 CF 3 Ph-4-Cl Si (CH 3 ) 3
3-I 2-CH 3 CF 3 Ph-4-Br CH 3
3-I 2-CH 3 CF 3 Ph-4-Br Et
3-I 2-CH 3 CF 3 Ph-4-Br n-Pr
3-I 2-CH 3 CF 3 Ph-4-Br i-Pr
3-I 2-CH 3 CF 3 Ph-4-Br n-Bu
3-I 2-CH 3 CF 3 Ph-4-Br CH 2 CF 3
3-I 2-CH 3 CF 3 Ph-4-Br CH 2 OCH 3
3-I 2-CH 3 CF 3 Ph-4-Br CH 2 OEt
3-I 2-CH 3 CF 3 Ph-4-Br CH 2 SCH 3
3-I 2-CH 3 CF 3 Ph-4-Br CH 2 CH = CH 2
3-I 2-CH 3 CF 3 Ph-4-Br CH 2 CH = CF 2
3-I 2-CH 3 CF 3 Ph-4-Br CH 2 CH = CCl 2
3-I 2-CH 3 CF 3 Ph-4-Br CH 2 CF = CF 2
3-I 2-CH 3 CF 3 Ph-4-Br CH 2 CCl = CCl 2
3-I 2-CH 3 CF 3 Ph-4-Br CH 2 C≡CH
3-I 2-CH 3 CF 3 Ph-4-Br CH 2 Ph
3-I 2-CH 3 CF 3 Ph-4-Br C (O) CH 3
3-I 2-CH 3 CF 3 Ph-4-Br C (O) Bu-t
3-I 2-CH 3 CF 3 Ph-4-Br C (O) SCH 3
3-I 2-CH 3 CF 3 Ph-4-Br C (S) SEt
3-I 2-CH 3 CF 3 Ph-4-Br Si (CH 3 ) 3
3-I 2-CH 3 CF 3 Ph-4-Br Si (CH 3 ) 2 Bu-t
3-I 2-CH 3 CF 3 Ph-4-Br Si (CH 3 ) 2 Ph
3-I 2-CH 3 CF 3 Ph-4-I CH 3
3-I 2-CH 3 CF 3 Ph-4-I CH 2 OCH 3
3-I 2-CH 3 CF 3 Ph-4-IC (O) CH 3
3-I 2-CH 3 CF 3 Ph-4-I Si (CH 3 ) 3
3-I 2-CH 3 CF 3 Ph-4-CF 3 CH 3
3-I 2-CH 3 CF 3 Ph-4-CF 3 Et
3-I 2-CH 3 CF 3 Ph-4-CF 3 n-Pr
3-I 2-CH 3 CF 3 Ph-4-CF 3 i-Pr
3-I 2-CH 3 CF 3 Ph-4-CF 3 n-Bu
3-I 2-CH 3 CF 3 Ph-4-CF 3 CH 2 CF 3
3-I 2-CH 3 CF 3 Ph-4-CF 3 CH 2 OCH 3
3-I 2-CH 3 CF 3 Ph-4-CF 3 CH 2 OEt
3-I 2-CH 3 CF 3 Ph-4-CF 3 CH 2 SCH 3
3-I 2-CH 3 CF 3 Ph-4-CF 3 CH 2 CH = CH 2
3-I 2-CH 3 CF 3 Ph-4-CF 3 CH 2 CH = CF 2
3-I 2-CH 3 CF 3 Ph-4-CF 3 CH 2 CH = CCl 2
3-I 2-CH 3 CF 3 Ph-4-CF 3 CH 2 CF = CF 2
3-I 2-CH 3 CF 3 Ph-4-CF 3 CH 2 CCl = CCl 2
3-I 2-CH 3 CF 3 Ph-4-CF 3 CH 2 C≡CH
3-I 2-CH 3 CF 3 Ph-4-CF 3 CH 2 Ph
3-I 2-CH 3 CF 3 Ph-4-CF 3 C (O) CH 3
3-I 2-CH 3 CF 3 Ph-4-CF 3 C (O) Bu-t
3-I 2-CH 3 CF 3 Ph-4-CF 3 C (O) SCH 3
3-I 2-CH 3 CF 3 Ph-4-CF 3 C (S) SEt
3-I 2-CH 3 CF 3 Ph-4-CF 3 Si (CH 3 ) 3
3-I 2-CH 3 CF 3 Ph-4-CF 3 Si (CH 3 ) 2 Bu-t
3-I 2-CH 3 CF 3 Ph-4-CF 3 Si (CH 3 ) 2 Ph
3-I 2-CH 3 CF 3 Ph-4-CHF 2 CH 3
3-I 2-CH 3 CF 3 Ph-4-CHF 2 CH 2 OCH 3
3-I 2-CH 3 CF 3 Ph-4-CHF 2 C (O) CH 3
3-I 2-CH 3 CF 3 Ph-4-CHF 2 Si (CH 3 ) 3
3-I 2-CH 3 CF 3 Ph-4-OCF 3 CH 3
3-I 2-CH 3 CF 3 Ph-4-OCF 3 Et
3-I 2-CH 3 CF 3 Ph-4-OCF 3 n-Pr
3-I 2-CH 3 CF 3 Ph-4-OCF 3 i-Pr
3-I 2-CH 3 CF 3 Ph-4-OCF 3 n-Bu
3-I 2-CH 3 CF 3 Ph-4-OCF 3 CH 2 CF 3
3-I 2-CH 3 CF 3 Ph-4-OCF 3 CH 2 OCH 3
3-I 2-CH 3 CF 3 Ph-4-OCF 3 CH 2 OEt
3-I 2-CH 3 CF 3 Ph-4-OCF 3 CH 2 SCH 3
3-I 2-CH 3 CF 3 Ph-4-OCF 3 CH 2 CH = CH 2
3-I 2-CH 3 CF 3 Ph-4-OCF 3 CH 2 CH = CF 2
3-I 2-CH 3 CF 3 Ph-4-OCF 3 CH 2 CH = CCl 2
3-I 2-CH 3 CF 3 Ph-4-OCF 3 CH 2 CF = CF 2
3-I 2-CH 3 CF 3 Ph-4-OCF 3 CH 2 CCl = CCl 2
3-I 2-CH 3 CF 3 Ph-4-OCF 3 CH 2 C≡CH
3-I 2-CH 3 CF 3 Ph-4-OCF 3 CH 2 Ph
3-I 2-CH 3 CF 3 Ph-4-OCF 3 C (O) CH 3
3-I 2-CH 3 CF 3 Ph-4-OCF 3 C (O) Bu-t
3-I 2-CH 3 CF 3 Ph-4-OCF 3 C (O) SCH 3
3-I 2-CH 3 CF 3 Ph-4-OCF 3 C (S) SEt
3-I 2-CH 3 CF 3 Ph-4-OCF 3 Si (CH 3 ) 3
3-I 2-CH 3 CF 3 Ph-4-OCF 3 Si (CH 3 ) 2 Bu-t
3-I 2-CH 3 CF 3 Ph-4-OCF 3 Si (CH 3 ) 2 Ph
3-I 2-CH 3 CF 3 Ph-4-OCF 2 Br CH 3
3-I 2-CH 3 CF 3 Ph-4-OCF 2 Br CH 2 OCH 3
3-I 2-CH 3 CF 3 Ph-4-OCF 2 Br C (O) CH 3
3-I 2-CH 3 CF 3 Ph-4-OCF 2 Br Si (CH 3 ) 3
3-I 2-CH 3 CF 3 Ph-4-OCF 2 CHF 2 CH 3
3-I 2-CH 3 CF 3 Ph-4-OCF 2 CHF 2 CH 2 OCH 3
3-I 2-CH 3 CF 3 Ph-4-OCF 2 CHF 2 C (O) CH 3
3-I 2-CH 3 CF 3 Ph-4-OCF 2 CHF 2 Si (CH 3 ) 3
3-I 2-CH 3 CF 3 Ph-4-OCF 2 CHFCl CH 3
3-I 2-CH 3 CF 3 Ph-4-OCF 2 CHFCl CH 2 OCH 3
3-I 2-CH 3 CF 3 Ph-4-OCF 2 CHFCl C (O) CH 3
3-I 2-CH 3 CF 3 Ph-4-OCF 2 CHFCl Si (CH 3 ) 3
3-I 2-CH 3 CF 3 Ph-4-OCF 2 CHFCF 3 CH 3
3-I 2-CH 3 CF 3 Ph-4-OCF 2 CHFCF 3 CH 2 OCH 3
3-I 2-CH 3 CF 3 Ph-4-OCF 2 CHFCF 3 C (O) CH 3
3-I 2-CH 3 CF 3 Ph-4-OCF 2 CHFCF 3 Si (CH 3 ) 3
3-I 2-CH 3 CF 3 Ph-4-OCF 2 CHFOCF 3 CH 3
3-I 2-CH 3 CF 3 Ph-4-OCF 2 CHFOCF 3 CH 2 OCH 3
3-I 2-CH 3 CF 3 Ph-4-OCF 2 CHFOCF 3 C (O) CH 3
3-I 2-CH 3 CF 3 Ph-4-OCF 2 CHFOCF 3 Si (CH 3 ) 3
3-I 2-CH 3 CF 3 Ph-4-OCF 2 CHFOCF 2 CF 2 CF 3 CH 3
3-I 2-CH 3 CF 3 Ph-4-OCF 2 CHFOCF 2 CF 2 CF 3 CH 2 OCH 3
3-I 2-CH 3 CF 3 Ph-4-OCF 2 CHFOCF 2 CF 2 CF 3 C (O) CH 3
3-I 2-CH 3 CF 3 Ph-4-OCF 2 CHFOCF 2 CF 2 CF 3 Si (CH 3 ) 3
3-I 2-CH 3 CF 3 Ph-4-O (L-45g) CH 3
3-I 2-CH 3 CF 3 Ph-4-O (L-45g) CH 2 OCH 3
3-I 2-CH 3 CF 3 Ph-4-O (L-45g) C (O) CH 3
3-I 2-CH 3 CF 3 Ph-4-O (L-45g) Si (CH 3 ) 3
3-I 2-CH 3 CF 3 Ph-3,4-F 2 CH 3
3-I 2-CH 3 CF 3 Ph-3,4-F 2 CH 2 OCH 3
3-I 2-CH 3 CF 3 Ph-3,4-F 2 C (O) CH 3
3-I 2-CH 3 CF 3 Ph-3,4-F 2 Si (CH 3 ) 3
3-I 2-CH 3 CF 3 Ph-3-F-4-Cl CH 3
3-I 2-CH 3 CF 3 Ph-3-F-4-Cl CH 2 OCH 3
3-I 2-CH 3 CF 3 Ph-3-F-4-Cl C (O) CH 3
3-I 2-CH 3 CF 3 Ph-3-F-4-Cl Si (CH 3 ) 3
3-I 2-CH 3 CF 3 Ph-3,4-Cl 2 CH 3
3-I 2-CH 3 CF 3 Ph-3,4-Cl 2 CH 2 OCH 3
3-I 2-CH 3 CF 3 Ph-3,4-Cl 2 C (O) CH 3
3-I 2-CH 3 CF 3 Ph-3,4-Cl 2 Si (CH 3 ) 3
3-I 2-CH 3 CF 3 Ph (-3-OCF 2 O-4-) CH 3
3-I 2-CH 3 CF 3 Ph (-3-OCF 2 O-4-) CH 2 OCH 3
3-I 2-CH 3 CF 3 Ph (-3-OCF 2 O-4-) C (O) CH 3
3-I 2-CH 3 CF 3 Ph (-3-OCF 2 O-4-) Si (CH 3 ) 3
3-I 2-CH 3 CF 3 Ph (-3-OCF 2 CF 2 O-4-) CH 3
3-I 2-CH 3 CF 3 Ph (-3-OCF 2 CF 2 O-4-) CH 2 OCH 3
3-I 2-CH 3 CF 3 Ph (-3-OCF 2 CF 2 O-4-) C (O) CH 3
3-I 2-CH 3 CF 3 Ph (-3-OCF 2 CF 2 O-4-) Si (CH 3 ) 3
3-I 2-CH 3 CF 3 (L-45c) Cl CH 3
3-I 2-CH 3 CF 3 (L-45c) Cl CH 2 OCH 3
3-I 2-CH 3 CF 3 (L-45c) Cl C (O) CH 3
3-I 2-CH 3 CF 3 (L-45c) Cl Si (CH 3 ) 3
3-I 2-CH 3 CF 3 (L-45c) Br CH 3
3-I 2-CH 3 CF 3 (L-45c) Br CH 2 OCH 3
3-I 2-CH 3 CF 3 (L-45c) Br C (O) CH 3
3-I 2-CH 3 CF 3 (L-45c) Br Si (CH 3 ) 3
3-I 2-CH 3 CF 3 (L-45c) CF 3 CH 3
3-I 2-CH 3 CF 3 (L-45c) CF 3 Et
3-I 2-CH 3 CF 3 (L-45c) CF 3 n-Pr
3-I 2-CH 3 CF 3 (L-45c) CF 3 i-Pr
3-I 2-CH 3 CF 3 (L-45c) CF 3 n-Bu
3-I 2-CH 3 CF 3 (L-45c) CF 3 CH 2 CF 3
3-I 2-CH 3 CF 3 (L-45c) CF 3 CH 2 OCH 3
3-I 2-CH 3 CF 3 (L-45c) CF 3 CH 2 OEt
3-I 2-CH 3 CF 3 (L-45c) CF 3 CH 2 SCH 3
3-I 2-CH 3 CF 3 (L-45c) CF 3 CH 2 CH = CH 2
3-I 2-CH 3 CF 3 (L-45c) CF 3 CH 2 CH = CF 2
3-I 2-CH 3 CF 3 (L-45c) CF 3 CH 2 CH = CCl 2
3-I 2-CH 3 CF 3 (L-45c) CF 3 CH 2 CF = CF 2
3-I 2-CH 3 CF 3 (L-45c) CF 3 CH 2 CCl = CCl 2
3-I 2-CH 3 CF 3 (L-45c) CF 3 CH 2 C≡CH
3-I 2-CH 3 CF 3 (L-45c) CF 3 CH 2 Ph
3-I 2-CH 3 CF 3 (L-45c) CF 3 C (O) CH 3
3-I 2-CH 3 CF 3 (L-45c) CF 3 C (O) Bu-t
3-I 2-CH 3 CF 3 (L-45c) CF 3 C (O) SCH 3
3-I 2-CH 3 CF 3 (L-45c) CF 3 C (S) SEt
3-I 2-CH 3 CF 3 (L-45c) CF 3 Si (CH 3 ) 3
3-I 2-CH 3 CF 3 (L-45c) CF 3 Si (CH 3 ) 2 Bu-t
3-I 2-CH 3 CF 3 (L-45c) CF 3 Si (CH 3 ) 2 Ph
3-I 2-CH 3 CF 3 L-45e CH 3
3-I 2-CH 3 CF 3 L-45e CH 2 OCH 3
3-I 2-CH 3 CF 3 L-45e C (O) CH 3
3-I 2-CH 3 CF 3 L-45e Si (CH 3 ) 3
3-I 2-CH 3 CF 3 L-45f CH 3
3-I 2-CH 3 CF 3 L-45f CH 2 OCH 3
3-I 2-CH 3 CF 3 L-45f C (O) CH 3
3-I 2-CH 3 CF 3 L-45f Si (CH 3 ) 3
3-I 2-CH 3 CF 3 (L-46c) Cl CH 3
3-I 2-CH 3 CF 3 (L-46c) Cl CH 2 OCH 3
3-I 2-CH 3 CF 3 (L-46c) Cl C (O) CH 3
3-I 2-CH 3 CF 3 (L-46c) Cl Si (CH 3 ) 3
3-I 2-CH 3 CF 3 (L-46c) Br CH 3
3-I 2-CH 3 CF 3 (L-46c) Br CH 2 OCH 3
3-I 2-CH 3 CF 3 (L-46c) Br C (O) CH 3
3-I 2-CH 3 CF 3 (L-46c) Br Si (CH 3 ) 3
3-I 2-CH 3 CF 3 (L-46c) CF 3 CH 3
3-I 2-CH 3 CF 3 (L-46c) CF 3 CH 2 OCH 3
3-I 2-CH 3 CF 3 (L-46c) CF 3 C (O) CH 3
3-I 2-CH 3 CF 3 (L-46c) CF 3 Si (CH 3 ) 3
3-I 2-CH 3 CF 3 L-46d CH 3
3-I 2-CH 3 CF 3 L-46d CH 2 OCH 3
3-I 2-CH 3 CF 3 L-46d C (O) CH 3
3-I 2-CH 3 CF 3 L-46d Si (CH 3 ) 3
3-I 2-Pr-n CF 3 Ph-4-OCF 3 H
3-I 2-Pr-i CF 3 (L-45c) CF 3 H
3-I 2-Bu-n CF 3 Ph-4-Br H
3-I 2-CF 3 CF 3 Ph-4-CF 3 H
3-I 2-CF 2 CF 3 CF 3 Ph-4-OCF 3 H
3-I 2-CH 2 OH CF 3 Ph-4-Br H
3-I 2-CH 2 OH CF 3 Ph-4-CF 3 H
3-I 2-CH 2 OH CF 3 Ph-4-OCF 3 H
3-I 2-CH 2 OH CF 3 (L-45c) CF 3 H
3-I 2-CH 2 OCH 3 CF 3 (L-45c) CF 3 H
3-I 2-CH 2 SCH 3 CF 3 Ph-4-Br H
3-I 2-OCH 3 CF 3 Ph-4-Br H
3-I 2-OCH 3 CF 3 Ph-4-CF 3 H
3-I 2-OCH 3 CF 3 Ph-4-OCF 3 H
3-I 2-OCH 3 CF 3 (L-45c) CF 3 H
3-I 2-OEt CF 3 Ph-4-CF 3 H
3-I 2-OPr-i CF 3 Ph-4-OCF 3 H
3-I 2-OCF 3 CF 3 (L-45c) CF 3 H
3-I 2-OPh CF 3 Ph-4-Br H
3-I 2-SCH 3 CF 3 Ph-4-Br H
3-I 2-SCH 3 CF 3 Ph-4-CF 3 H
3-I 2-SCH 3 CF 3 Ph-4-OCF 3 H
3-I 2-SCH 3 CF 3 (L-45c) CF 3 H
3-I 2-SO 2 CH 3 CF 3 Ph-4-CF 3 H
3-I 2-SEt CF 3 Ph-4-OCF 3 H
3-I 2-SPr-i CF 3 (L-45c) CF 3 H
3-I 2-SCHF 2 CF 3 Ph-4-Br H
3-I 2-N (CH 3 ) 2 CF 3 Ph-4-CF 3 H
3-I 2-CN CF 3 Ph-4-OCF 3 H
3-I 2-Ph CF 3 (L-45c) CF 3 H
3-I 2- (L-14a) CF 3 Ph-4-Br H
3-I 2- (L-14b) CF 3 Ph-4-CF 3 H
3-I 2- (L-14c) CF 3 Ph-4-OCF 3 H
3-I 2- (L-14d) CF 3 (L-45c) CF 3 H
3-I 2- (L-14e) CF 3 Ph-4-Br H
3-I 2- (L-14f) CF 3 Ph-4-CF 3 H
3-I 2-CH 3 -3-F CF 3 Ph-4-OCF 3 H
3-I 2-CH 3 -5-F CF 3 (L-45c) CF 3 H
3-I 2-CH 3 -3-Cl CF 3 Ph-4-Br H
3-I 2-CH 3 -5-Cl CF 3 Ph-4-CF 3 H
3-I 2,3- (CH 3 ) 2 CF 3 Ph-4-OCF 3 H
3-I 2,5- (CH 3 ) 2 CF 3 (L-45c) CF 3 H
3-I 2,6- (CH 3 ) 2 CF 3 Ph-4-Br H
3-I 2-CH 3 -3-OCH 3 CF 3 Ph-4-CF 3 H
3-I 2-CH 3 -3-OCHF 2 CF 3 Ph-4-OCF 3 H
3-I 2-CH 3 -3,5-Cl 2 CF 3 (L-45c) CF 3 H
4-I 2-CH 3 CF 3 Ph-4-Br H
5-I 2-CH 3 CF 3 Ph-4-CF 3 H
6-I 2-CH 3 CF 3 Ph-4-OCF 3 H
3-I-4-Cl 2-CH 3 CF 3 (L-45c) CF 3 H
4-Cl-6-I 2-CH 3 CF 3 Ph-4-Br H
5-CH 3 2-CH 3 CF 3 Ph-4-CF 3 H
6-CH 3 2-CH 3 CF 3 Ph-4-OCF 3 H
3-Cl-4-CH 3 2-CH 3 CF 3 Ph-4-Br H
3-Cl-4-CH 3 2-CH 3 CF 3 Ph-4-CF 3 H
3-Cl-4-CH 3 2-CH 3 CF 3 Ph-4-OCF 3 H
3-Cl-4-CH 3 2-CH 3 CF 3 (L-45c) CF 3 H
6-Et 2-CH 3 CF 3 (L-45c) CF 3 H
4-CF 3 2-CH 3 CF 3 Ph-4-Br H
6-CF 3 2-CH 3 CF 3 Ph-4-CF 3 H
3-CF 2 CF 3 2-CH 3 CF 3 Ph-4-OCF 3 H
3-OCH 3 2-CH 3 CF 3 (L-45c) CF 3 H
6-OCH 3 2-CH 3 CF 3 Ph-4-Br H
3-Cl-4-OCH 3 2-CH 3 CF 3 Ph-4-CF 3 H
3-OCH 2 O-4 2-CH 3 CF 3 Ph-4-OCF 3 H
5-OCHF 2 2-CH 3 CF 3 (L-45c) CF 3 H
6-OCHF 2 2-CH 3 CF 3 Ph-4-Br H
5-OCF 3 2-CH 3 CF 3 Ph-4-CF 3 H
3-OSO 2 CH 3 2-CH 3 CF 3 CF 2 O (Ph-4-Cl) H
3-OSO 2 CH 3 2-CH 3 CF 3 CH = CH (Ph-4-Cl) H
3-OSO 2 CH 3 2-CH 3 CF 3 CH = CH (Ph-4-Br) H
3-OSO 2 CH 3 2-CH 3 CF 3 CH = CH (Ph-4-CF 3 ) H
3-OSO 2 CH 3 2-CH 3 CF 3 CH = CH (Ph-4-OCF 3 ) H
3-OSO 2 CH 3 2-CH 3 CF 3 CH = CH (Ph-3,4-Cl 2 ) H
3-OSO 2 CH 3 2-CH 3 CF 3 Ph-4-FH
3-OSO 2 CH 3 2-CH 3 CF 3 Ph-4-Cl H
3-OSO 2 CH 3 2-CH 3 CF 3 Ph-4-Br H
3-OSO 2 CH 3 2-CH 3 CF 3 Ph-4-CF 3 H
3-OSO 2 CH 3 2-CH 3 CF 3 Ph-4-OCF 3 H
3-OSO 2 CH 3 2-CH 3 CF 3 Ph-4-OCF 2 Br H
3-OSO 2 CH 3 2-CH 3 CF 3 Ph-4-OCF 2 CHF 2 H
3-OSO 2 CH 3 2-CH 3 CF 3 Ph-4-OCF 2 CHFCF 3 H
3-OSO 2 CH 3 2-CH 3 CF 3 Ph-4-OCF 2 CHFOCF 3 H
3-OSO 2 CH 3 2-CH 3 CF 3 Ph-4-OCF 2 CHFOCF 2 CF 2 CF 3 H
3-OSO 2 CH 3 2-CH 3 CF 3 Ph-4-O (L-45g) H
3-OSO 2 CH 3 2-CH 3 CF 3 Ph-3,4-F 2 H
3-OSO 2 CH 3 2-CH 3 CF 3 Ph-3-F-4-Cl H
3-OSO 2 CH 3 2-CH 3 CF 3 Ph-3,4-Cl 2 H
3-OSO 2 CH 3 2-CH 3 CF 3 Ph (-3-OCF 2 O-4-) H
3-OSO 2 CH 3 2-CH 3 CF 3 Ph (-3-OCF 2 CF 2 O-4-) H
3-OSO 2 CH 3 2-CH 3 CF 3 (L-45c) CF 3 H
3-OSO 2 CH 3 2-CH 3 CF 3 L-45f H
3-OSO 2 CH 3 2-CH 3 CF 3 (L-46c) CF 3 H
3-OSO 2 CH 3 2-CH 3 CF 3 L-46d H
3-OSO 2 Et 2-CH 3 CF 3 Ph-4-OCF 3 H
3-OSO 2 CF 3 2-CH 3 CF 3 (L-45c) CF 3 H
3-OCF 2 O-4 2-CH 3 CF 3 CF 2 O (Ph-4-Cl) H
3-OCF 2 O-4 2-CH 3 CF 3 CH = CH (Ph-4-Cl) H
3-OCF 2 O-4 2-CH 3 CF 3 CH = CH (Ph-4-Br) H
3-OCF 2 O-4 2-CH 3 CF 3 CH = CH (Ph-4-CF 3 ) H
3-OCF 2 O-4 2-CH 3 CF 3 CH = CH (Ph-4-OCF 3 ) H
3-OCF 2 O-4 2-CH 3 CF 3 CH = CH (Ph-3,4-Cl 2 ) H
3-OCF 2 O-4 2-CH 3 CF 3 Ph-4-FH
3-OCF 2 O-4 2-CH 3 CF 3 Ph-4-Cl H
3-OCF 2 O-4 2-CH 3 CF 3 Ph-4-Br H
3-OCF 2 O-4 2-CH 3 CF 3 Ph-4-CF 3 H
3-OCF 2 O-4 2-CH 3 CF 3 Ph-4-OCF 3 H
3-OCF 2 O-4 2-CH 3 CF 3 Ph-4-OCF 2 Br H
3-OCF 2 O-4 2-CH 3 CF 3 Ph-4-OCF 2 CHF 2 H
3-OCF 2 O-4 2-CH 3 CF 3 Ph-4-OCF 2 CHFCF 3 H
3-OCF 2 O-4 2-CH 3 CF 3 Ph-4-OCF 2 CHFOCF 3 H
3-OCF 2 O-4 2-CH 3 CF 3 Ph-4-OCF 2 CHFOCF 2 CF 2 CF 3 H
3-OCF 2 O-4 2-CH 3 CF 3 Ph-4-O (L-45g) H
3-OCF 2 O-4 2-CH 3 CF 3 Ph-3,4-F 2 H
3-OCF 2 O-4 2-CH 3 CF 3 Ph-3-F-4-Cl H
3-OCF 2 O-4 2-CH 3 CF 3 Ph-3,4-Cl 2 H
3-OCF 2 O-4 2-CH 3 CF 3 Ph (-3-OCF 2 O-4-) H
3-OCF 2 O-4 2-CH 3 CF 3 Ph (-3-OCF 2 CF 2 O-4-) H
3-OCF 2 O-4 2-CH 3 CF 3 (L-45c) CF 3 H
3-OCF 2 O-4 2-CH 3 CF 3 L-45f H
3-OCF 2 O-4 2-CH 3 CF 3 (L-46c) CF 3 H
3-OCF 2 O-4 2-CH 3 CF 3 L-46d H
3-OCF 2 CF 2 O-4 2-CH 3 CF 3 CH = CH (Ph-4-Cl) H
3-OCF 2 CF 2 O-4 2-CH 3 CF 3 Ph-4-Cl H
3-OCF 2 CF 2 O-4 2-CH 3 CF 3 Ph-4-Br H
3-OCF 2 CF 2 O-4 2-CH 3 CF 3 Ph-4-CF 3 H
3-OCF 2 CF 2 O-4 2-CH 3 CF 3 Ph-4-OCF 3 H
3-OCF 2 CF 2 O-4 2-CH 3 CF 3 Ph-4-OCF 2 Br H
3-OCF 2 CF 2 O-4 2-CH 3 CF 3 Ph-4-OCF 2 CHFCF 3 H
3-OCF 2 CF 2 O-4 2-CH 3 CF 3 Ph-4-OCF 2 CHFOCF 3 H
3-OCF 2 CF 2 O-4 2-CH 3 CF 3 Ph-4-OCF 2 CHFOCF 2 CF 2 CF 3 H
3-OCF 2 CF 2 O-4 2-CH 3 CF 3 Ph-4-O (L-45g) H
3-OCF 2 CF 2 O-4 2-CH 3 CF 3 Ph-3,4-Cl 2 H
3-OCF 2 CF 2 O-4 2-CH 3 CF 3 Ph (-3-OCF 2 O-4-) H
3-OCF 2 CF 2 O-4 2-CH 3 CF 3 Ph (-3-OCF 2 CF 2 O-4-) H
3-OCF 2 CF 2 O-4 2-CH 3 CF 3 (L-45c) CF 3 H
3-OCF 2 CF 2 O-4 2-CH 3 CF 3 L-45f H
3-OCF 2 CF 2 O-4 2-CH 3 CF 3 (L-46c) CF 3 H
3-OCF 2 CF 2 O-4 2-CH 3 CF 3 L-46d H
6-SCH 3 2-CH 3 CF 3 Ph-4-Br H
6-SO 2 CH 3 2-CH 3 CF 3 Ph-4-CF 3 H
3-SEt 2-CH 3 CF 3 Ph-4-OCF 3 H
3-SO 2 Et 2-CH 3 CF 3 (L-45c) CF 3 H
3-SPr-i 2-CH 3 CF 3 Ph-4-Br H
3-S (O) Pr-i 2-CH 3 CF 3 Ph-4-CF 3 H
3-SO 2 Pr-i 2-CH 3 CF 3 Ph-4-OCF 3 H
6-S (O) CF 3 2-CH 3 CF 3 (L-45c) CF 3 H
3-SCH 2 CF 3 2-CH 3 CF 3 Ph-4-Br H
6-SCH 2 CF 3 2-CH 3 CF 3 Ph-4-CF 3 H
3-S (O) CH 2 CF 3 2-CH 3 CF 3 Ph-4-OCF 3 H
6-S (O) CH 2 CF 3 2-CH 3 CF 3 (L-45c) CF 3 H
3-SO 2 CH 2 CF 3 2-CH 3 CF 3 Ph-4-Br H
3-Cl-6-SCF 3 2-CH 3 CF 3 Ph-4-CF 3 H
6-NO 2 2-CH 3 CF 3 Ph-4-OCF 3 H
3-CN 2-CH 3 CF 3 (L-45c) CF 3 H
6-C (O) OCH 3 2-CH 3 CF 3 Ph-4-Br H
3-C (O) NHPr-i 2-CH 3 CF 3 Ph-4-CF 3 H
3-C≡CH 2-CH 3 CF 3 Ph-4-OCF 3 H
3-C≡CSi (CH 3 ) 3 2-CH 3 CF 3 (L-45c) CF 3 H
6-C≡CH 2-CH 3 CF 3 Ph-4-Br H
6-Ph 2-CH 3 CF 3 Ph-4-CF 3 H
3-CH = CH-CH = CH-4 2-CH 3 CF 3 Ph-4-OCF 3 H
4-CH = CH-CH = CH-5 2-CH 3 CF 3 (L-45c) CF 3 H
3-Si (CH 3 ) 3 2-CH 3 CF 3 Ph-4-Br H
―――――――――――――――――――――――――――――――――――――――
Table 4 In the table, the number representing the substitution position of the substituent (X) m corresponds to the position of the number described in the following structural formula, and the-sign represents no substitution. .

Figure 2005126418
Figure 2005126418

―――――――――――――――――――――――――――――――――――――――
(X)m Y R1 R6
―――――――――――――――――――――――――――――――――――――――
3-F CH3 i-Pr H
3-F CH3 CH(CH3)CH2SCH3 H
3-F CH3 CH(CH3)CH2S(O)CH3 H
3-F CH3 CH(CH3)CH2SO2CH3 H
3-F CH3 C(CH3)2CH2SCH3 H
3-F CH3 C(CH3)2CH2S(O)CH3 H
3-F CH3 C(CH3)2CH2SO2CH3 H
3-Cl CH3 i-Pr H
3-Cl CH3 CH(CH3)CH2SCH3 H
3-Cl CH3 CH(CH3)CH2S(O)CH3 H
3-Cl CH3 CH(CH3)CH2SO2CH3 H
3-Cl CH3 C(CH3)2CH2SCH3 H
3-Cl CH3 C(CH3)2CH2S(O)CH3 H
3-Cl CH3 C(CH3)2CH2SO2CH3 H
3,4-Cl2 CH3 i-Pr H
3,4-Cl2 CH3 CH(CH3)CH2SCH3 H
3,4-Cl2 CH3 CH(CH3)CH2S(O)CH3 H
3,4-Cl2 CH3 CH(CH3)CH2SO2CH3 H
3,4-Cl2 CH3 C(CH3)2CH2SCH3 H
3,4-Cl2 CH3 C(CH3)2CH2S(O)CH3 H
3,4-Cl2 CH3 C(CH3)2CH2SO2CH3 H
3-Br CH3 i-Pr H
3-Br CH3 CH(CH3)CH2SCH3 H
3-Br CH3 CH(CH3)CH2S(O)CH3 H
3-Br CH3 CH(CH3)CH2SO2CH3 H
3-Br CH3 C(CH3)2CH2SCH3 H
3-Br CH3 C(CH3)2CH2S(O)CH3 H
3-Br CH3 C(CH3)2CH2SO2CH3 H
3-I − i-Pr H
3-I − CH(CH3)CH2SCH3 H
3-I − CH(CH3)CH2S(O)CH3 H
3-I − CH(CH3)CH2SO2CH3 H
3-I − C(CH3)2CH2SCH3 H
3-I − C(CH3)2CH2S(O)CH3 H
3-I − C(CH3)2CH2SO2CH3 H
3-I F i-Pr H
3-I F CH(CH3)CH2SCH3 H
3-I F CH(CH3)CH2S(O)CH3 H
3-I F CH(CH3)CH2SO2CH3 H
3-I F C(CH3)2CH2SCH3 H
3-I F C(CH3)2CH2S(O)CH3 H
3-I F C(CH3)2CH2SO2CH3 H
3-I Cl i-Pr H
3-I Cl CH(CH3)CH2SCH3 H
3-I Cl CH(CH3)CH2S(O)CH3 H
3-I Cl CH(CH3)CH2SO2CH3 H
3-I Cl C(CH3)2CH2SCH3 H
3-I Cl C(CH3)2CH2S(O)CH3 H
3-I Cl C(CH3)2CH2SO2CH3 H
3-I Br i-Pr H
3-I Br CH(CH3)CH2SCH3 H
3-I Br CH(CH3)CH2S(O)CH3 H
3-I Br CH(CH3)CH2SO2CH3 H
3-I Br C(CH3)2CH2SCH3 H
3-I Br C(CH3)2CH2S(O)CH3 H
3-I Br C(CH3)2CH2SO2CH3 H
3-I CH3 CH3 H
3-I CH3 Et H
3-I CH3 i-Pr H
3-I CH3 i-Pr CH3
3-I CH3 i-Pr CH2OCH3
3-I CH3 i-Pr C(O)CH3
3-I CH3 i-Pr Si(CH3)3
3-I CH3 s-Bu H
3-I CH3 t-Bu H
3-I CH3 CH(CH3)Pr-n H
3-I CH3 CH(CH3)CH2OCH3 H
3-I CH3 CH(CH3)CH2OC(O)CH3 H
3-I CH3 CH(CH3)CH2OC(O)NHCH3 H
3-I CH3 CH(CH3)CH2OC(O)NHEt H
3-I CH3 CH(CH3)CH2OC(O)NHPr-n H
3-I CH3 CH(CH3)CH2OC(O)NHPr-i H
3-I CH3 CH(CH3)CH2OC(O)NHPr-c H
3-I CH3 CH(CH3)CH2OC(O)NHCH2Ph H
3-I CH3 CH(CH3)CH2OC(O)NHPh H
3-I CH3 CH(CH3)CH2OC(O)N(Et)2 H
3-I CH3 CH(CH3)CH2OP(S)(OCH3)2 H
3-I CH3 CH(CH3)CH2OP(S)(OEt)2 H
3-I CH3 C(CH3)2CH2OCH3 H
3-I CH3 C(CH3)2CH2OC(O)NHCH3 H
3-I CH3 C(CH3)2CH2OC(O)NHEt H
3-I CH3 C(CH3)2CH2OC(O)NHPr-n H
3-I CH3 C(CH3)2CH2OC(O)NHCH2Ph H
3-I CH3 C(CH3)2CH2OC(O)N(CH3)2 H
3-I CH3 CH(CH3)CH2CH2OEt H
3-I CH3 CH(CH3)CH2SCH3 H
3-I CH3 CH(CH3)CH2SCH3 CH3
3-I CH3 CH(CH3)CH2SCH3 CH2OCH3
3-I CH3 CH(CH3)CH2SCH3 C(O)CH3
3-I CH3 CH(CH3)CH2SCH3 Si(CH3)3
3-I CH3 CH(CH3)CH2S(O)CH3 H
3-I CH3 CH(CH3)CH2S(O)CH3 CH3
3-I CH3 CH(CH3)CH2S(O)CH3 CH2OCH3
3-I CH3 CH(CH3)CH2S(O)CH3 C(O)CH3
3-I CH3 CH(CH3)CH2S(O)CH3 Si(CH3)3
3-I CH3 CH(CH3)CH2SO2CH3 H
3-I CH3 CH(CH3)CH2SO2CH3 CH3
3-I CH3 CH(CH3)CH2SO2CH3 CH2OCH3
3-I CH3 CH(CH3)CH2SO2CH3 C(O)CH3
3-I CH3 CH(CH3)CH2SO2CH3 Si(CH3)3
3-I CH3 CH(CH3)CH2SEt H
3-I CH3 CH(CH3)CH2S(O)Et H
3-I CH3 CH(CH3)CH2SO2Et H
3-I CH3 CH(CH3)CH2SCH2Si(CH3)3 H
3-I CH3 CH(CH3)CH2SSCH3 H
3-I CH3 CH(CH3)CH2SO2NHEt H
3-I CH3 CH(CH3)CH2SO2N(Et)2 H
3-I CH3 C(CH3)2CH2SCH3 H
3-I CH3 C(CH3)2CH2SCH3 CH3
3-I CH3 C(CH3)2CH2SCH3 CH2OCH3
3-I CH3 C(CH3)2CH2SCH3 C(O)CH3
3-I CH3 C(CH3)2CH2SCH3 Si(CH3)3
3-I CH3 C(CH3)2CH2S(O)CH3 H
3-I CH3 C(CH3)2CH2S(O)CH3 CH3
3-I CH3 C(CH3)2CH2S(O)CH3 CH2OCH3
3-I CH3 C(CH3)2CH2S(O)CH3 C(O)CH3
3-I CH3 C(CH3)2CH2S(O)CH3 Si(CH3)3
3-I CH3 C(CH3)2CH2SO2CH3 H
3-I CH3 C(CH3)2CH2SO2CH3 CH3
3-I CH3 C(CH3)2CH2SO2CH3 CH2OCH3
3-I CH3 C(CH3)2CH2SO2CH3 C(O)CH3
3-I CH3 C(CH3)2CH2SO2CH3 Si(CH3)3
3-I CH3 C(CH3)2CH2SEt H
3-I CH3 C(CH3)2CH2S(O)Et H
3-I CH3 C(CH3)2CH2SO2Et H
3-I CH3 C(CH3)2CH2SO2N(Et)2 H
3-I CH3 CH(CH3)CH2N(CH3)SO2CH3 H
3-I CH3 C(CH3)2CH2NHC(O)OCH3 H
3-I CH3 CH(CH3)CH=NOCH3 H
3-I CH3 C(CH3)2CH=NOCH3 H
3-I CH3 C(CH3)2CH=CH2 H
3-I CH3 C(CH3)2C≡CH H
3-I Et i-Pr H
3-I Et CH(CH3)CH2SCH3 H
3-I Et CH(CH3)CH2S(O)CH3 H
3-I Et CH(CH3)CH2SO2CH3 H
3-I Et C(CH3)2CH2SCH3 H
3-I Et C(CH3)2CH2S(O)CH3 H
3-I Et C(CH3)2CH2SO2CH3 H
3-I OCH3 i-Pr H
3-I OCH3 CH(CH3)CH2SCH3 H
3-I OCH3 CH(CH3)CH2S(O)CH3 H
3-I OCH3 CH(CH3)CH2SO2CH3 H
3-I OCH3 C(CH3)2CH2SCH3 H
3-I OCH3 C(CH3)2CH2S(O)CH3 H
3-I OCH3 C(CH3)2CH2SO2CH3 H
3-I SCH3 i-Pr H
3-I SCH3 CH(CH3)CH2SCH3 H
3-I SCH3 CH(CH3)CH2S(O)CH3 H
3-I SCH3 CH(CH3)CH2SO2CH3 H
3-I SCH3 C(CH3)2CH2SCH3 H
3-I SCH3 C(CH3)2CH2S(O)CH3 H
3-I SCH3 C(CH3)2CH2SO2CH3 H
3-CH3 CH3 i-Pr H
3-CH3 CH3 CH(CH3)CH2SCH3 H
3-CH3 CH3 CH(CH3)CH2S(O)CH3 H
3-CH3 CH3 CH(CH3)CH2SO2CH3 H
3-CH3 CH3 C(CH3)2CH2SCH3 H
3-CH3 CH3 C(CH3)2CH2S(O)CH3 H
3-CH3 CH3 C(CH3)2CH2SO2CH3 H
3-CF3 CH3 i-Pr H
3-CF3 CH3 CH(CH3)CH2SCH3 H
3-CF3 CH3 CH(CH3)CH2S(O)CH3 H
3-CF3 CH3 CH(CH3)CH2SO2CH3 H
3-CF3 CH3 C(CH3)2CH2SCH3 H
3-CF3 CH3 C(CH3)2CH2S(O)CH3 H
3-CF3 CH3 C(CH3)2CH2SO2CH3 H
3-OCHF2 CH3 i-Pr H
3-OCHF2 CH3 CH(CH3)CH2SCH3 H
3-OCHF2 CH3 CH(CH3)CH2S(O)CH3 H
3-OCHF2 CH3 CH(CH3)CH2SO2CH3 H
3-OCHF2 CH3 C(CH3)2CH2SCH3 H
3-OCHF2 CH3 C(CH3)2CH2S(O)CH3 H
3-OCHF2 CH3 C(CH3)2CH2SO2CH3 H
3-OCF3 CH3 i-Pr H
3-OCF3 CH3 CH(CH3)CH2SCH3 H
3-OCF3 CH3 CH(CH3)CH2S(O)CH3 H
3-OCF3 CH3 CH(CH3)CH2SO2CH3 H
3-OCF3 CH3 C(CH3)2CH2SCH3 H
3-OCF3 CH3 C(CH3)2CH2S(O)CH3 H
3-OCF3 CH3 C(CH3)2CH2SO2CH3 H
3-OSO2CH3 CH3 i-Pr H
3-OSO2CH3 CH3 CH(CH3)CH2SCH3 H
3-OSO2CH3 CH3 CH(CH3)CH2S(O)CH3 H
3-OSO2CH3 CH3 CH(CH3)CH2SO2CH3 H
3-OSO2CH3 CH3 C(CH3)2CH2SCH3 H
3-OSO2CH3 CH3 C(CH3)2CH2S(O)CH3 H
3-OSO2CH3 CH3 C(CH3)2CH2SO2CH3 H
3-OCF2O-4 CH3 i-Pr H
3-OCF2O-4 CH3 CH(CH3)CH2SCH3 H
3-OCF2O-4 CH3 CH(CH3)CH2S(O)CH3 H
3-OCF2O-4 CH3 CH(CH3)CH2SO2CH3 H
3-OCF2O-4 CH3 C(CH3)2CH2SCH3 H
3-OCF2O-4 CH3 C(CH3)2CH2S(O)CH3 H
3-OCF2O-4 CH3 C(CH3)2CH2SO2CH3 H
3-SCH3 CH3 i-Pr H
3-SCH3 CH3 CH(CH3)CH2SCH3 H
3-SCH3 CH3 CH(CH3)CH2S(O)CH3 H
3-SCH3 CH3 CH(CH3)CH2SO2CH3 H
3-SCH3 CH3 C(CH3)2CH2SCH3 H
3-SCH3 CH3 C(CH3)2CH2S(O)CH3 H
3-SCH3 CH3 C(CH3)2CH2SO2CH3 H
3-S(O)CH3 CH3 i-Pr H
3-S(O)CH3 CH3 CH(CH3)CH2SCH3 H
3-S(O)CH3 CH3 CH(CH3)CH2S(O)CH3 H
3-S(O)CH3 CH3 CH(CH3)CH2SO2CH3 H
3-S(O)CH3 CH3 C(CH3)2CH2SCH3 H
3-S(O)CH3 CH3 C(CH3)2CH2S(O)CH3 H
3-S(O)CH3 CH3 C(CH3)2CH2SO2CH3 H
3-SO2CH3 CH3 i-Pr H
3-SO2CH3 CH3 CH(CH3)CH2SCH3 H
3-SO2CH3 CH3 CH(CH3)CH2S(O)CH3 H
3-SO2CH3 CH3 CH(CH3)CH2SO2CH3 H
3-SO2CH3 CH3 C(CH3)2CH2SCH3 H
3-SO2CH3 CH3 C(CH3)2CH2S(O)CH3 H
3-SO2CH3 CH3 C(CH3)2CH2SO2CH3 H
3-SCHF2 CH3 i-Pr H
3-SCHF2 CH3 CH(CH3)CH2SCH3 H
3-SCHF2 CH3 CH(CH3)CH2S(O)CH3 H
3-SCHF2 CH3 CH(CH3)CH2SO2CH3 H
3-SCHF2 CH3 C(CH3)2CH2SCH3 H
3-SCHF2 CH3 C(CH3)2CH2S(O)CH3 H
3-SCHF2 CH3 C(CH3)2CH2SO2CH3 H
3-S(O)CHF2 CH3 i-Pr H
3-S(O)CHF2 CH3 CH(CH3)CH2SCH3 H
3-S(O)CHF2 CH3 CH(CH3)CH2S(O)CH3 H
3-S(O)CHF2 CH3 CH(CH3)CH2SO2CH3 H
3-S(O)CHF2 CH3 C(CH3)2CH2SCH3 H
3-S(O)CHF2 CH3 C(CH3)2CH2S(O)CH3 H
3-S(O)CHF2 CH3 C(CH3)2CH2SO2CH3 H
3-SO2CHF2 CH3 i-Pr H
3-SO2CHF2 CH3 CH(CH3)CH2SCH3 H
3-SO2CHF2 CH3 CH(CH3)CH2S(O)CH3 H
3-SO2CHF2 CH3 CH(CH3)CH2SO2CH3 H
3-SO2CHF2 CH3 C(CH3)2CH2SCH3 H
3-SO2CHF2 CH3 C(CH3)2CH2S(O)CH3 H
3-SO2CHF2 CH3 C(CH3)2CH2SO2CH3 H
3-SCF3 CH3 i-Pr H
3-SCF3 CH3 CH(CH3)CH2SCH3 H
3-SCF3 CH3 CH(CH3)CH2S(O)CH3 H
3-SCF3 CH3 CH(CH3)CH2SO2CH3 H
3-SCF3 CH3 C(CH3)2CH2SCH3 H
3-SCF3 CH3 C(CH3)2CH2S(O)CH3 H
3-SCF3 CH3 C(CH3)2CH2SO2CH3 H
3-S(O)CF3 CH3 i-Pr H
3-S(O)CF3 CH3 CH(CH3)CH2SCH3 H
3-S(O)CF3 CH3 CH(CH3)CH2S(O)CH3 H
3-S(O)CF3 CH3 CH(CH3)CH2SO2CH3 H
3-S(O)CF3 CH3 C(CH3)2CH2SCH3 H
3-S(O)CF3 CH3 C(CH3)2CH2S(O)CH3 H
3-S(O)CF3 CH3 C(CH3)2CH2SO2CH3 H
3-SO2CF3 CH3 i-Pr H
3-SO2CF3 CH3 CH(CH3)CH2SCH3 H
3-SO2CF3 CH3 CH(CH3)CH2S(O)CH3 H
3-SO2CF3 CH3 CH(CH3)CH2SO2CH3 H
3-SO2CF3 CH3 C(CH3)2CH2SCH3 H
3-SO2CF3 CH3 C(CH3)2CH2S(O)CH3 H
3-SO2CF3 CH3 C(CH3)2CH2SO2CH3 H
3-NO2 CH3 i-Pr H
3-NO2 CH3 CH(CH3)CH2SCH3 H
3-NO2 CH3 CH(CH3)CH2S(O)CH3 H
3-NO2 CH3 CH(CH3)CH2SO2CH3 H
3-NO2 CH3 C(CH3)2CH2SCH3 H
3-NO2 CH3 C(CH3)2CH2S(O)CH3 H
3-NO2 CH3 C(CH3)2CH2SO2CH3 H
―――――――――――――――――――――――――――――――――――――――
第５表 ―――――――――――――――――――――――――――――――――――――――
(X) m YR 1 R 6
―――――――――――――――――――――――――――――――――――――――
3-F CH 3 i-Pr H
3-F CH 3 CH (CH 3 ) CH 2 SCH 3 H
3-F CH 3 CH (CH 3 ) CH 2 S (O) CH 3 H
3-F CH 3 CH (CH 3 ) CH 2 SO 2 CH 3 H
3-F CH 3 C (CH 3 ) 2 CH 2 SCH 3 H
3-F CH 3 C (CH 3 ) 2 CH 2 S (O) CH 3 H
3-F CH 3 C (CH 3 ) 2 CH 2 SO 2 CH 3 H
3-Cl CH 3 i-Pr H
3-Cl CH 3 CH (CH 3 ) CH 2 SCH 3 H
3-Cl CH 3 CH (CH 3 ) CH 2 S (O) CH 3 H
3-Cl CH 3 CH (CH 3 ) CH 2 SO 2 CH 3 H
3-Cl CH 3 C (CH 3 ) 2 CH 2 SCH 3 H
3-Cl CH 3 C (CH 3 ) 2 CH 2 S (O) CH 3 H
3-Cl CH 3 C (CH 3 ) 2 CH 2 SO 2 CH 3 H
3,4-Cl 2 CH 3 i-Pr H
3,4-Cl 2 CH 3 CH (CH 3 ) CH 2 SCH 3 H
3,4-Cl 2 CH 3 CH (CH 3 ) CH 2 S (O) CH 3 H
3,4-Cl 2 CH 3 CH (CH 3 ) CH 2 SO 2 CH 3 H
3,4-Cl 2 CH 3 C (CH 3 ) 2 CH 2 SCH 3 H
3,4-Cl 2 CH 3 C (CH 3 ) 2 CH 2 S (O) CH 3 H
3,4-Cl 2 CH 3 C (CH 3 ) 2 CH 2 SO 2 CH 3 H
3-Br CH 3 i-Pr H
3-Br CH 3 CH (CH 3 ) CH 2 SCH 3 H
3-Br CH 3 CH (CH 3 ) CH 2 S (O) CH 3 H
3-Br CH 3 CH (CH 3 ) CH 2 SO 2 CH 3 H
3-Br CH 3 C (CH 3 ) 2 CH 2 SCH 3 H
3-Br CH 3 C (CH 3 ) 2 CH 2 S (O) CH 3 H
3-Br CH 3 C (CH 3 ) 2 CH 2 SO 2 CH 3 H
3-I − i-Pr H
3-I − CH (CH 3 ) CH 2 SCH 3 H
3-I − CH (CH 3 ) CH 2 S (O) CH 3 H
3-I − CH (CH 3 ) CH 2 SO 2 CH 3 H
3-I − C (CH 3 ) 2 CH 2 SCH 3 H
3-I − C (CH 3 ) 2 CH 2 S (O) CH 3 H
3-I − C (CH 3 ) 2 CH 2 SO 2 CH 3 H
3-IF i-Pr H
3-IF CH (CH 3 ) CH 2 SCH 3 H
3-IF CH (CH 3 ) CH 2 S (O) CH 3 H
3-IF CH (CH 3 ) CH 2 SO 2 CH 3 H
3-IFC (CH 3 ) 2 CH 2 SCH 3 H
3-IFC (CH 3 ) 2 CH 2 S (O) CH 3 H
3-IFC (CH 3 ) 2 CH 2 SO 2 CH 3 H
3-I Cl i-Pr H
3-I Cl CH (CH 3 ) CH 2 SCH 3 H
3-I Cl CH (CH 3 ) CH 2 S (O) CH 3 H
3-I Cl CH (CH 3 ) CH 2 SO 2 CH 3 H
3-I Cl C (CH 3 ) 2 CH 2 SCH 3 H
3-I Cl C (CH 3 ) 2 CH 2 S (O) CH 3 H
3-I Cl C (CH 3 ) 2 CH 2 SO 2 CH 3 H
3-I Br i-Pr H
3-I Br CH (CH 3 ) CH 2 SCH 3 H
3-I Br CH (CH 3 ) CH 2 S (O) CH 3 H
3-I Br CH (CH 3 ) CH 2 SO 2 CH 3 H
3-I Br C (CH 3 ) 2 CH 2 SCH 3 H
3-I Br C (CH 3 ) 2 CH 2 S (O) CH 3 H
3-I Br C (CH 3 ) 2 CH 2 SO 2 CH 3 H
3-I CH 3 CH 3 H
3-I CH 3 Et H
3-I CH 3 i-Pr H
3-I CH 3 i-Pr CH 3
3-I CH 3 i-Pr CH 2 OCH 3
3-I CH 3 i-Pr C (O) CH 3
3-I CH 3 i-Pr Si (CH 3 ) 3
3-I CH 3 s-Bu H
3-I CH 3 t-Bu H
3-I CH 3 CH (CH 3 ) Pr-n H
3-I CH 3 CH (CH 3 ) CH 2 OCH 3 H
3-I CH 3 CH (CH 3 ) CH 2 OC (O) CH 3 H
3-I CH 3 CH (CH 3 ) CH 2 OC (O) NHCH 3 H
3-I CH 3 CH (CH 3 ) CH 2 OC (O) NHEt H
3-I CH 3 CH (CH 3 ) CH 2 OC (O) NHPr-n H
3-I CH 3 CH (CH 3 ) CH 2 OC (O) NHPr-i H
3-I CH 3 CH (CH 3 ) CH 2 OC (O) NHPr-c H
3-I CH 3 CH (CH 3 ) CH 2 OC (O) NHCH 2 Ph H
3-I CH 3 CH (CH 3 ) CH 2 OC (O) NHPh H
3-I CH 3 CH (CH 3 ) CH 2 OC (O) N (Et) 2 H
3-I CH 3 CH (CH 3 ) CH 2 OP (S) (OCH 3 ) 2 H
3-I CH 3 CH (CH 3 ) CH 2 OP (S) (OEt) 2 H
3-I CH 3 C (CH 3 ) 2 CH 2 OCH 3 H
3-I CH 3 C (CH 3 ) 2 CH 2 OC (O) NHCH 3 H
3-I CH 3 C (CH 3 ) 2 CH 2 OC (O) NHEt H
3-I CH 3 C (CH 3 ) 2 CH 2 OC (O) NHPr-n H
3-I CH 3 C (CH 3 ) 2 CH 2 OC (O) NHCH 2 Ph H
3-I CH 3 C (CH 3 ) 2 CH 2 OC (O) N (CH 3 ) 2 H
3-I CH 3 CH (CH 3 ) CH 2 CH 2 OEt H
3-I CH 3 CH (CH 3 ) CH 2 SCH 3 H
3-I CH 3 CH (CH 3 ) CH 2 SCH 3 CH 3
3-I CH 3 CH (CH 3 ) CH 2 SCH 3 CH 2 OCH 3
3-I CH 3 CH (CH 3 ) CH 2 SCH 3 C (O) CH 3
3-I CH 3 CH (CH 3 ) CH 2 SCH 3 Si (CH 3 ) 3
3-I CH 3 CH (CH 3 ) CH 2 S (O) CH 3 H
3-I CH 3 CH (CH 3 ) CH 2 S (O) CH 3 CH 3
3-I CH 3 CH (CH 3 ) CH 2 S (O) CH 3 CH 2 OCH 3
3-I CH 3 CH (CH 3 ) CH 2 S (O) CH 3 C (O) CH 3
3-I CH 3 CH (CH 3 ) CH 2 S (O) CH 3 Si (CH 3 ) 3
3-I CH 3 CH (CH 3 ) CH 2 SO 2 CH 3 H
3-I CH 3 CH (CH 3 ) CH 2 SO 2 CH 3 CH 3
3-I CH 3 CH (CH 3 ) CH 2 SO 2 CH 3 CH 2 OCH 3
3-I CH 3 CH (CH 3 ) CH 2 SO 2 CH 3 C (O) CH 3
3-I CH 3 CH (CH 3 ) CH 2 SO 2 CH 3 Si (CH 3 ) 3
3-I CH 3 CH (CH 3 ) CH 2 SEt H
3-I CH 3 CH (CH 3 ) CH 2 S (O) Et H
3-I CH 3 CH (CH 3 ) CH 2 SO 2 Et H
3-I CH 3 CH (CH 3 ) CH 2 SCH 2 Si (CH 3 ) 3 H
3-I CH 3 CH (CH 3 ) CH 2 SSCH 3 H
3-I CH 3 CH (CH 3 ) CH 2 SO 2 NHEt H
3-I CH 3 CH (CH 3 ) CH 2 SO 2 N (Et) 2 H
3-I CH 3 C (CH 3 ) 2 CH 2 SCH 3 H
3-I CH 3 C (CH 3 ) 2 CH 2 SCH 3 CH 3
3-I CH 3 C (CH 3 ) 2 CH 2 SCH 3 CH 2 OCH 3
3-I CH 3 C (CH 3 ) 2 CH 2 SCH 3 C (O) CH 3
3-I CH 3 C (CH 3 ) 2 CH 2 SCH 3 Si (CH 3 ) 3
3-I CH 3 C (CH 3 ) 2 CH 2 S (O) CH 3 H
3-I CH 3 C (CH 3 ) 2 CH 2 S (O) CH 3 CH 3
3-I CH 3 C (CH 3 ) 2 CH 2 S (O) CH 3 CH 2 OCH 3
3-I CH 3 C (CH 3 ) 2 CH 2 S (O) CH 3 C (O) CH 3
3-I CH 3 C (CH 3 ) 2 CH 2 S (O) CH 3 Si (CH 3 ) 3
3-I CH 3 C (CH 3 ) 2 CH 2 SO 2 CH 3 H
3-I CH 3 C (CH 3 ) 2 CH 2 SO 2 CH 3 CH 3
3-I CH 3 C (CH 3 ) 2 CH 2 SO 2 CH 3 CH 2 OCH 3
3-I CH 3 C (CH 3 ) 2 CH 2 SO 2 CH 3 C (O) CH 3
3-I CH 3 C (CH 3 ) 2 CH 2 SO 2 CH 3 Si (CH 3 ) 3
3-I CH 3 C (CH 3 ) 2 CH 2 SEt H
3-I CH 3 C (CH 3 ) 2 CH 2 S (O) Et H
3-I CH 3 C (CH 3 ) 2 CH 2 SO 2 Et H
3-I CH 3 C (CH 3 ) 2 CH 2 SO 2 N (Et) 2 H
3-I CH 3 CH (CH 3 ) CH 2 N (CH 3 ) SO 2 CH 3 H
3-I CH 3 C (CH 3 ) 2 CH 2 NHC (O) OCH 3 H
3-I CH 3 CH (CH 3 ) CH = NOCH 3 H
3-I CH 3 C (CH 3 ) 2 CH = NOCH 3 H
3-I CH 3 C (CH 3 ) 2 CH = CH 2 H
3-I CH 3 C (CH 3 ) 2 C≡CH H
3-I Et i-Pr H
3-I Et CH (CH 3 ) CH 2 SCH 3 H
3-I Et CH (CH 3 ) CH 2 S (O) CH 3 H
3-I Et CH (CH 3 ) CH 2 SO 2 CH 3 H
3-I Et C (CH 3 ) 2 CH 2 SCH 3 H
3-I Et C (CH 3 ) 2 CH 2 S (O) CH 3 H
3-I Et C (CH 3 ) 2 CH 2 SO 2 CH 3 H
3-I OCH 3 i-Pr H
3-I OCH 3 CH (CH 3 ) CH 2 SCH 3 H
3-I OCH 3 CH (CH 3 ) CH 2 S (O) CH 3 H
3-I OCH 3 CH (CH 3 ) CH 2 SO 2 CH 3 H
3-I OCH 3 C (CH 3 ) 2 CH 2 SCH 3 H
3-I OCH 3 C (CH 3 ) 2 CH 2 S (O) CH 3 H
3-I OCH 3 C (CH 3 ) 2 CH 2 SO 2 CH 3 H
3-I SCH 3 i-Pr H
3-I SCH 3 CH (CH 3 ) CH 2 SCH 3 H
3-I SCH 3 CH (CH 3 ) CH 2 S (O) CH 3 H
3-I SCH 3 CH (CH 3 ) CH 2 SO 2 CH 3 H
3-I SCH 3 C (CH 3 ) 2 CH 2 SCH 3 H
3-I SCH 3 C (CH 3 ) 2 CH 2 S (O) CH 3 H
3-I SCH 3 C (CH 3 ) 2 CH 2 SO 2 CH 3 H
3-CH 3 CH 3 i-Pr H
3-CH 3 CH 3 CH (CH 3 ) CH 2 SCH 3 H
3-CH 3 CH 3 CH (CH 3 ) CH 2 S (O) CH 3 H
3-CH 3 CH 3 CH (CH 3 ) CH 2 SO 2 CH 3 H
3-CH 3 CH 3 C (CH 3 ) 2 CH 2 SCH 3 H
3-CH 3 CH 3 C (CH 3 ) 2 CH 2 S (O) CH 3 H
3-CH 3 CH 3 C (CH 3 ) 2 CH 2 SO 2 CH 3 H
3-CF 3 CH 3 i-Pr H
3-CF 3 CH 3 CH (CH 3 ) CH 2 SCH 3 H
3-CF 3 CH 3 CH (CH 3 ) CH 2 S (O) CH 3 H
3-CF 3 CH 3 CH (CH 3 ) CH 2 SO 2 CH 3 H
3-CF 3 CH 3 C (CH 3 ) 2 CH 2 SCH 3 H
3-CF 3 CH 3 C (CH 3 ) 2 CH 2 S (O) CH 3 H
3-CF 3 CH 3 C (CH 3 ) 2 CH 2 SO 2 CH 3 H
3-OCHF 2 CH 3 i-Pr H
3-OCHF 2 CH 3 CH (CH 3 ) CH 2 SCH 3 H
3-OCHF 2 CH 3 CH (CH 3 ) CH 2 S (O) CH 3 H
3-OCHF 2 CH 3 CH (CH 3 ) CH 2 SO 2 CH 3 H
3-OCHF 2 CH 3 C (CH 3 ) 2 CH 2 SCH 3 H
3-OCHF 2 CH 3 C (CH 3 ) 2 CH 2 S (O) CH 3 H
3-OCHF 2 CH 3 C (CH 3 ) 2 CH 2 SO 2 CH 3 H
3-OCF 3 CH 3 i-Pr H
3-OCF 3 CH 3 CH (CH 3 ) CH 2 SCH 3 H
3-OCF 3 CH 3 CH (CH 3 ) CH 2 S (O) CH 3 H
3-OCF 3 CH 3 CH (CH 3 ) CH 2 SO 2 CH 3 H
3-OCF 3 CH 3 C (CH 3 ) 2 CH 2 SCH 3 H
3-OCF 3 CH 3 C (CH 3 ) 2 CH 2 S (O) CH 3 H
3-OCF 3 CH 3 C (CH 3 ) 2 CH 2 SO 2 CH 3 H
3-OSO 2 CH 3 CH 3 i-Pr H
3-OSO 2 CH 3 CH 3 CH (CH 3 ) CH 2 SCH 3 H
3-OSO 2 CH 3 CH 3 CH (CH 3 ) CH 2 S (O) CH 3 H
3-OSO 2 CH 3 CH 3 CH (CH 3 ) CH 2 SO 2 CH 3 H
3-OSO 2 CH 3 CH 3 C (CH 3 ) 2 CH 2 SCH 3 H
3-OSO 2 CH 3 CH 3 C (CH 3 ) 2 CH 2 S (O) CH 3 H
3-OSO 2 CH 3 CH 3 C (CH 3 ) 2 CH 2 SO 2 CH 3 H
3-OCF 2 O-4 CH 3 i-Pr H
3-OCF 2 O-4 CH 3 CH (CH 3 ) CH 2 SCH 3 H
3-OCF 2 O-4 CH 3 CH (CH 3 ) CH 2 S (O) CH 3 H
3-OCF 2 O-4 CH 3 CH (CH 3 ) CH 2 SO 2 CH 3 H
3-OCF 2 O-4 CH 3 C (CH 3 ) 2 CH 2 SCH 3 H
3-OCF 2 O-4 CH 3 C (CH 3 ) 2 CH 2 S (O) CH 3 H
3-OCF 2 O-4 CH 3 C (CH 3 ) 2 CH 2 SO 2 CH 3 H
3-SCH 3 CH 3 i-Pr H
3-SCH 3 CH 3 CH (CH 3 ) CH 2 SCH 3 H
3-SCH 3 CH 3 CH (CH 3 ) CH 2 S (O) CH 3 H
3-SCH 3 CH 3 CH (CH 3 ) CH 2 SO 2 CH 3 H
3-SCH 3 CH 3 C (CH 3 ) 2 CH 2 SCH 3 H
3-SCH 3 CH 3 C (CH 3 ) 2 CH 2 S (O) CH 3 H
3-SCH 3 CH 3 C (CH 3 ) 2 CH 2 SO 2 CH 3 H
3-S (O) CH 3 CH 3 i-Pr H
3-S (O) CH 3 CH 3 CH (CH 3 ) CH 2 SCH 3 H
3-S (O) CH 3 CH 3 CH (CH 3 ) CH 2 S (O) CH 3 H
3-S (O) CH 3 CH 3 CH (CH 3 ) CH 2 SO 2 CH 3 H
3-S (O) CH 3 CH 3 C (CH 3 ) 2 CH 2 SCH 3 H
3-S (O) CH 3 CH 3 C (CH 3 ) 2 CH 2 S (O) CH 3 H
3-S (O) CH 3 CH 3 C (CH 3 ) 2 CH 2 SO 2 CH 3 H
3-SO 2 CH 3 CH 3 i-Pr H
3-SO 2 CH 3 CH 3 CH (CH 3 ) CH 2 SCH 3 H
3-SO 2 CH 3 CH 3 CH (CH 3 ) CH 2 S (O) CH 3 H
3-SO 2 CH 3 CH 3 CH (CH 3 ) CH 2 SO 2 CH 3 H
3-SO 2 CH 3 CH 3 C (CH 3 ) 2 CH 2 SCH 3 H
3-SO 2 CH 3 CH 3 C (CH 3 ) 2 CH 2 S (O) CH 3 H
3-SO 2 CH 3 CH 3 C (CH 3 ) 2 CH 2 SO 2 CH 3 H
3-SCHF 2 CH 3 i-Pr H
3-SCHF 2 CH 3 CH (CH 3 ) CH 2 SCH 3 H
3-SCHF 2 CH 3 CH (CH 3 ) CH 2 S (O) CH 3 H
3-SCHF 2 CH 3 CH (CH 3 ) CH 2 SO 2 CH 3 H
3-SCHF 2 CH 3 C (CH 3 ) 2 CH 2 SCH 3 H
3-SCHF 2 CH 3 C (CH 3 ) 2 CH 2 S (O) CH 3 H
3-SCHF 2 CH 3 C (CH 3 ) 2 CH 2 SO 2 CH 3 H
3-S (O) CHF 2 CH 3 i-Pr H
3-S (O) CHF 2 CH 3 CH (CH 3 ) CH 2 SCH 3 H
3-S (O) CHF 2 CH 3 CH (CH 3 ) CH 2 S (O) CH 3 H
3-S (O) CHF 2 CH 3 CH (CH 3 ) CH 2 SO 2 CH 3 H
3-S (O) CHF 2 CH 3 C (CH 3 ) 2 CH 2 SCH 3 H
3-S (O) CHF 2 CH 3 C (CH 3 ) 2 CH 2 S (O) CH 3 H
3-S (O) CHF 2 CH 3 C (CH 3 ) 2 CH 2 SO 2 CH 3 H
3-SO 2 CHF 2 CH 3 i-Pr H
3-SO 2 CHF 2 CH 3 CH (CH 3 ) CH 2 SCH 3 H
3-SO 2 CHF 2 CH 3 CH (CH 3 ) CH 2 S (O) CH 3 H
3-SO 2 CHF 2 CH 3 CH (CH 3 ) CH 2 SO 2 CH 3 H
3-SO 2 CHF 2 CH 3 C (CH 3 ) 2 CH 2 SCH 3 H
3-SO 2 CHF 2 CH 3 C (CH 3 ) 2 CH 2 S (O) CH 3 H
3-SO 2 CHF 2 CH 3 C (CH 3 ) 2 CH 2 SO 2 CH 3 H
3-SCF 3 CH 3 i-Pr H
3-SCF 3 CH 3 CH (CH 3 ) CH 2 SCH 3 H
3-SCF 3 CH 3 CH (CH 3 ) CH 2 S (O) CH 3 H
3-SCF 3 CH 3 CH (CH 3 ) CH 2 SO 2 CH 3 H
3-SCF 3 CH 3 C (CH 3 ) 2 CH 2 SCH 3 H
3-SCF 3 CH 3 C (CH 3 ) 2 CH 2 S (O) CH 3 H
3-SCF 3 CH 3 C (CH 3 ) 2 CH 2 SO 2 CH 3 H
3-S (O) CF 3 CH 3 i-Pr H
3-S (O) CF 3 CH 3 CH (CH 3 ) CH 2 SCH 3 H
3-S (O) CF 3 CH 3 CH (CH 3 ) CH 2 S (O) CH 3 H
3-S (O) CF 3 CH 3 CH (CH 3 ) CH 2 SO 2 CH 3 H
3-S (O) CF 3 CH 3 C (CH 3 ) 2 CH 2 SCH 3 H
3-S (O) CF 3 CH 3 C (CH 3 ) 2 CH 2 S (O) CH 3 H
3-S (O) CF 3 CH 3 C (CH 3 ) 2 CH 2 SO 2 CH 3 H
3-SO 2 CF 3 CH 3 i-Pr H
3-SO 2 CF 3 CH 3 CH (CH 3 ) CH 2 SCH 3 H
3-SO 2 CF 3 CH 3 CH (CH 3 ) CH 2 S (O) CH 3 H
3-SO 2 CF 3 CH 3 CH (CH 3 ) CH 2 SO 2 CH 3 H
3-SO 2 CF 3 CH 3 C (CH 3 ) 2 CH 2 SCH 3 H
3-SO 2 CF 3 CH 3 C (CH 3 ) 2 CH 2 S (O) CH 3 H
3-SO 2 CF 3 CH 3 C (CH 3 ) 2 CH 2 SO 2 CH 3 H
3-NO 2 CH 3 i-Pr H
3-NO 2 CH 3 CH (CH 3 ) CH 2 SCH 3 H
3-NO 2 CH 3 CH (CH 3 ) CH 2 S (O) CH 3 H
3-NO 2 CH 3 CH (CH 3 ) CH 2 SO 2 CH 3 H
3-NO 2 CH 3 C (CH 3 ) 2 CH 2 SCH 3 H
3-NO 2 CH 3 C (CH 3 ) 2 CH 2 S (O) CH 3 H
3-NO 2 CH 3 C (CH 3 ) 2 CH 2 SO 2 CH 3 H
―――――――――――――――――――――――――――――――――――――――
Table 5

Figure 2005126418
Figure 2005126418

Figure 2005126418
Figure 2005126418

―――――――――――――――――――――――――――――――――――――――
R4 Y2 R5 Y3 R6
―――――――――――――――――――――――――――――――――――――――
CH3 H CF2O(Ph-4-Cl) H H
CH3 H CH=CH(Ph-4-Cl) H H
CH3 H CH=CH(Ph-4-OCF3) H H
CH3 H CH=CH(Ph-3,4-Cl2) H H
CH3 H Ph-4-F H H
CH3 H Ph-4-Cl H H
CH3 H Ph-4-Br H H
CH3 H Ph-4-I H H
CH3 H Ph-4-CF3 H H
CH3 H Ph-4-OCHF2 H H
CH3 H Ph-4-OCF3 H H
CH3 H Ph-4-OCF2Br H H
CH3 H Ph-4-OCF2CHF2 H H
CH3 H Ph-4-OCF2CHFCl H H
CH3 H Ph-4-OCF2CHFCF3 H H
CH3 H Ph-4-OCF2CHFOCF3 H H
CH3 H Ph-4-OCF2CHFOCF2CF2CF3 H H
CH3 H Ph-4-O(L-45g) H H
CH3 H Ph-3,4-Cl2 H H
CH3 H Ph(-3-OCF2O-4-) H H
CH3 H Ph(-3-OCF2CF2O-4-) H H
CH3 H (L-45c)Cl H H
CH3 H (L-45c)Br H H
CH3 H (L-45c)CF3 H H
CH3 H L-45e H H
CH3 H L-45f H H
CH3 H (L-46c)Cl H H
CH3 H (L-46c)Br H H
CH3 H (L-46c)CF3 H H
CH3 H L-46d H H
Et H CF2O(Ph-4-Cl) H H
Et H CH=CH(Ph-4-Cl) H H
Et H CH=CH(Ph-4-OCF3) H H
Et H CH=CH(Ph-3,4-Cl2) H H
Et H Ph-4-Cl H H
Et H Ph-4-Br H H
Et H Ph-4-CF3 H H
Et H Ph-4-OCF3 H H
Et H Ph-4-OCF2Br H H
Et H Ph-4-OCF2CHFCF3 H H
Et H Ph-4-OCF2CHFOCF3 H H
Et H Ph-4-OCF2CHFOCF2CF2CF3 H H
Et H Ph-4-O(L-45g) H H
Et H Ph-3,4-Cl2 H H
Et H Ph(-3-OCF2O-4-) H H
Et H Ph(-3-OCF2CF2O-4-) H H
Et H (L-45c)Br H H
Et H (L-45c)CF3 H H
Et H L-45e H H
Et H L-45f H H
Et H (L-46c)Br H H
Et H (L-46c)CF3 H H
Et H L-46d H H
n-Pr H Ph-4-Br H H
n-Pr H Ph-4-CF3 H H
n-Pr H Ph-4-OCF3 H H
n-Pr H (L-45c)CF3 H H
i-Pr H Ph-4-Br H H
i-Pr H Ph-4-CF3 H H
i-Pr H Ph-4-OCF3 H H
i-Pr H (L-45c)CF3 H H
c-Pr H Ph-4-Br H H
c-Pr H Ph-4-CF3 H H
c-Pr H Ph-4-OCF3 H H
c-Pr H (L-45c)CF3 H H
n-Bu H Ph-4-Br H H
CH2F H Ph-4-CF3 H H
CH2Cl H Ph-4-OCF3 H H
CH2Br H (L-45c)CF3 H H
CHF2 H CF2O(Ph-4-Cl) H H
CHF2 H CH=CH(Ph-4-Cl) H H
CHF2 H CH=CH(Ph-4-OCF3) H H
CHF2 H CH=CH(Ph-3,4-Cl2) H H
CHF2 H Ph-4-F H H
CHF2 H Ph-4-Cl H H
CHF2 H Ph-4-Br H H
CHF2 H Ph-4-I H H
CHF2 H Ph-4-CF3 H H
CHF2 H Ph-4-OCHF2 H H
CHF2 H Ph-4-OCF3 H H
CHF2 H Ph-4-OCF2Br H H
CHF2 H Ph-4-OCF2CHF2 H H
CHF2 H Ph-4-OCF2CHFCl H H
CHF2 H Ph-4-OCF2CHFCF3 H H
CHF2 H Ph-4-OCF2CHFOCF3 H H
CHF2 H Ph-4-OCF2CHFOCF2CF2CF3 H H
CHF2 H Ph-4-O(L-45g) H H
CHF2 H Ph-3,4-Cl2 H H
CHF2 H Ph(-3-OCF2O-4-) H H
CHF2 H Ph(-3-OCF2CF2O-4-) H H
CHF2 H (L-45c)Cl H H
CHF2 H (L-45c)Br H H
CHF2 H (L-45c)CF3 H H
CHF2 H L-45e H H
CHF2 H L-45f H H
CHF2 H (L-46c)Cl H H
CHF2 H (L-46c)Br H H
CHF2 H (L-46c)CF3 H H
CHF2 H L-46d H H
CHFCl H Ph-4-Br H H
CHFBr H Ph-4-CF3 H H
CF3 H CH2OCH3 H H
CF3 H CH2OEt H H
CF3 H CH2OPr-n H H
CF3 H CH2OPr-i H H
CF3 H CH2OBu-n H H
CF3 H CH2OCH2CF3 H H
CF3 H CH2OCH2CF2CF3 H H
CF3 H CH2OCH(CF3)2 H H
CF3 H CH2OPh H H
CF3 H CH2O(Ph-4-F) H H
CF3 H CH2O(Ph-2-Cl) H H
CF3 H CH2O(Ph-3-Cl) H H
CF3 H CH2O(Ph-4-Cl) H H
CF3 H CH2O(Ph-4-Br) H H
CF3 H CH2O(Ph-4-CF3) H H
CF3 H CH2O(Ph-2-OCF3) H H
CF3 H CH2O(Ph-3-OCF3) H H
CF3 H CH2O(Ph-4-OCF3) H H
CF3 H CF2OPh H H
CF3 H CF2O(Ph-3-F) H H
CF3 H CF2O(Ph-4-F) H H
CF3 H CF2O(Ph-2-Cl) H H
CF3 H CF2O(Ph-3-Cl) H H
CF3 H CF2O(Ph-4-Cl) H H
CF3 H CF2O(Ph-3-Br) H H
CF3 H CF2O(Ph-4-Br) H H
CF3 H CF2O(Ph-3-CF3) H H
CF3 H CF2O(Ph-4-CF3) H H
CF3 H CF2O(Ph-3-OCF3) H H
CF3 H CF2O(Ph-4-OCF3) H H
CF3 H CH2SPh H H
CF3 H CH2S(Ph-3-Cl) H H
CF3 H CH2S(Ph-4-Cl) H H
CF3 H CH2SO2(Ph-3-Cl) H H
CF3 H CH2SO2(Ph-4-Cl) H H
CF3 H CH2N(CH3)2 H H
CF3 H CH2NHPh H H
CF3 H CH2NH(Ph-3-Cl) H H
CF3 H CH2NH(Ph-4-Cl) H H
CF3 H CF2C(O)OEt H H
CF3 H CH2(L-5a) H H
CF3 H CH2(L-14a) H H
CF3 H CH2(L-24a) H H
CF3 H CH2(L-36a) H H
CF3 H C(O)OEt H H
CF3 H C(O)OBu-t H H
CF3 H C(O)OCH2CF3 H H
CF3 H CH=CHPh H H
CF3 H CH=CH(Ph-3-F) H H
CF3 H CH=CH(Ph-4-F) H H
CF3 H CH=CH(Ph-2-Cl) H H
CF3 H CH=CH(Ph-3-Cl) H H
CF3 H CH=CH(Ph-4-Cl) H H
CF3 H CH=CH(Ph-3-Br) H H
CF3 H CH=CH(Ph-4-Br) H H
CF3 H CH=CH(Ph-3-CF3) H H
CF3 H CH=CH(Ph-4-CF3) H H
CF3 H CH=CH(Ph-3-OCF3) H H
CF3 H CH=CH(Ph-4-OCF3) H H
CF3 H CH=CH(Ph-3-SCH3) H H
CF3 H CH=CH(Ph-4-SCH3) H H
CF3 H CH=CH(Ph-3-SO2CH3) H H
CF3 H CH=CH(Ph-4-SO2CH3) H H
CF3 H CH=CH(Ph-3,4-F2) H H
CF3 H CH=CH(Ph-3-F-4-Cl) H H
CF3 H CH=CH(Ph-3,4-Cl2) H H
CF3 H CH=CH(Ph-3,4-Br2) H H
CF3 H CH=CH(Ph-3-F-4-CF3) H H
CF3 H CH=CH(Ph-3-Cl-4-OCF3) H H
CF3 H CH=CH[Ph(-3-OCF2O-4-)] H H
CF3 H Ph H H
CF3 H Ph-2-F H H
CF3 H Ph-3-F H H
CF3 H Ph-4-F H H
CF3 H Ph-2-Cl H H
CF3 H Ph-3-Cl H H
CF3 H Ph-4-Cl H H
CF3 H Ph-3-Br H H
CF3 H Ph-4-Br H H
CF3 H Ph-4-Br H CH3
CF3 H Ph-4-Br H Et
CF3 H Ph-4-Br H n-Pr
CF3 H Ph-4-Br H i-Pr
CF3 H Ph-4-Br H n-Bu
CF3 H Ph-4-Br H CH2CF3
CF3 H Ph-4-Br H CH2OCH3
CF3 H Ph-4-Br H CH2OEt
CF3 H Ph-4-Br H CH2SCH3
CF3 H Ph-4-Br H CH2CH=CH2
CF3 H Ph-4-Br H CH2CH=CF2
CF3 H Ph-4-Br H CH2CH=CCl2
CF3 H Ph-4-Br H CH2CF=CF2
CF3 H Ph-4-Br H CH2CCl=CCl2
CF3 H Ph-4-Br H CH2C≡CH
CF3 H Ph-4-Br H CH2Ph
CF3 H Ph-4-Br H Si(CH3)3
CF3 H Ph-4-Br H Si(CH3)2Bu-t
CF3 H Ph-4-Br H Si(CH3)2Ph
CF3 H Ph-4-I H H
CF3 H Ph-4-Bu-t H H
CF3 H Ph-3-CF3 H H
CF3 H Ph-4-CF3 H H
CF3 H Ph-4-CF3 H CH3
CF3 H Ph-4-CF3 H Et
CF3 H Ph-4-CF3 H n-Pr
CF3 H Ph-4-CF3 H i-Pr
CF3 H Ph-4-CF3 H n-Bu
CF3 H Ph-4-CF3 H CH2CF3
CF3 H Ph-4-CF3 H CH2OCH3
CF3 H Ph-4-CF3 H CH2OEt
CF3 H Ph-4-CF3 H CH2SCH3
CF3 H Ph-4-CF3 H CH2CH=CH2
CF3 H Ph-4-CF3 H CH2CH=CF2
CF3 H Ph-4-CF3 H CH2CH=CCl2
CF3 H Ph-4-CF3 H CH2CF=CF2
CF3 H Ph-4-CF3 H CH2CCl=CCl2
CF3 H Ph-4-CF3 H CH2C≡CH
CF3 H Ph-4-CF3 H CH2Ph
CF3 H Ph-4-CF3 H Si(CH3)3
CF3 H Ph-4-CF3 H Si(CH3)2Bu-t
CF3 H Ph-4-CF3 H Si(CH3)2Ph
CF3 H Ph-4-OCH3 H H
CF3 H Ph-4-OCHF2 H H
CF3 H Ph-3-OCF3 H H
CF3 H Ph-4-OCF3 H H
CF3 H Ph-4-OCF3 H CH3
CF3 H Ph-4-OCF3 H Et
CF3 H Ph-4-OCF3 H n-Pr
CF3 H Ph-4-OCF3 H i-Pr
CF3 H Ph-4-OCF3 H n-Bu
CF3 H Ph-4-OCF3 H CH2CF3
CF3 H Ph-4-OCF3 H CH2OCH3
CF3 H Ph-4-OCF3 H CH2OEt
CF3 H Ph-4-OCF3 H CH2SCH3
CF3 H Ph-4-OCF3 H CH2CH=CH2
CF3 H Ph-4-OCF3 H CH2CH=CF2
CF3 H Ph-4-OCF3 H CH2CH=CCl2
CF3 H Ph-4-OCF3 H CH2CF=CF2
CF3 H Ph-4-OCF3 H CH2CCl=CCl2
CF3 H Ph-4-OCF3 H CH2C≡CH
CF3 H Ph-4-OCF3 H CH2Ph
CF3 H Ph-4-OCF3 H Si(CH3)3
CF3 H Ph-4-OCF3 H Si(CH3)2Bu-t
CF3 H Ph-4-OCF3 H Si(CH3)2Ph
CF3 H Ph-4-OCF2Br H H
CF3 H Ph-4-OCH2CF3 H H
CF3 H Ph-4-OCF2CHF2 H H
CF3 H Ph-4-OCF2CHFCl H H
CF3 H Ph-4-OCF2CHFBr H H
CF3 H Ph-4-OCF2CF2Br H H
CF3 H Ph-4-OCF2CFCl2 H H
CF3 H Ph-4-OCF2CCl3 H H
CF3 H Ph-4-OCH2CF2CHF2 H H
CF3 H Ph-3-OCF2CHFCF3 H H
CF3 H Ph-4-OCF2CHFCF3 H H
CF3 H Ph-4-OCH(CF3)2 H H
CF3 H Ph-4-OCF2CFBrCF3 H H
CF3 H Ph-3-OCF2CHFOCF3 H H
CF3 H Ph-4-OCF2CHFOCF3 H H
CF3 H Ph-4-OCF2CHFOCF2CF2CF3 H H
CF3 H Ph-4-OSO2CH3 H H
CF3 H Ph-4-OSO2CF3 H H
CF3 H Ph-3-O(Ph-4-Cl) H H
CF3 H Ph-4-O(Ph-4-Cl) H H
CF3 H Ph-4-O(Ph-4-Br) H H
CF3 H Ph-4-O(Ph-4-CF3) H H
CF3 H Ph-4-O(L-45c)Br H H
CF3 H Ph-4-O(L-45c)CF3 H H
CF3 H Ph-3-O(L-45e) H H
CF3 H Ph-4-O(L-45e) H H
CF3 H Ph-4-O(L-48b)Br H H
CF3 H Ph-4-SCH3 H H
CF3 H Ph-4-SO2CH3 H H
CF3 H Ph-3-S(Ph-4-Cl) H H
CF3 H Ph-4-S(Ph-4-Cl) H H
CF3 H Ph-4-S(Ph-4-Br) H H
CF3 H Ph-4-S(Ph-4-CF3) H H
CF3 H Ph-4-S(L-45c)Br H H
CF3 H Ph-4-S(L-45c)CF3 H H
CF3 H Ph-4-S(L-45e) H H
CF3 H Ph-4-S(L-48b)Br H H
CF3 H Ph-4-NO2 H H
CF3 H Ph-4-CN H H
CF3 H Ph-2,3-F2 H H
CF3 H Ph-2,4-F2 H H
CF3 H Ph-3,4-F2 H H
CF3 H Ph-2,5-F2 H H
CF3 H Ph-3,5-F2 H H
CF3 H Ph-2-Cl-4-F H H
CF3 H Ph-2-F-3-Cl H H
CF3 H Ph-3-Cl-4-F H H
CF3 H Ph-2-F-4-Cl H H
CF3 H Ph-3-F-4-Cl H H
CF3 H Ph-2,3-Cl2 H H
CF3 H Ph-2,4-Cl2 H H
CF3 H Ph-2,5-Cl2 H H
CF3 H Ph-3,4-Cl2 H H
CF3 H Ph-3,5-Cl2 H H
CF3 H Ph-3-Br-4-F H H
CF3 H Ph-2-F-4-Br H H
CF3 H Ph-2-F-5-Br H H
CF3 H Ph-3,4-Br2 H H
CF3 H Ph-3,5-Br2 H H
CF3 H Ph-3-CH3-4-F H H
CF3 H Ph-3-F-4-CH3 H H
CF3 H Ph-2-F-5-CH3 H H
CF3 H Ph-2,4-(CH3)2 H H
CF3 H Ph-3,4-(CH3)2 H H
CF3 H Ph-2-F-3-CF3 H H
CF3 H Ph-3-CF3-4-F H H
CF3 H Ph-3-CF3-4-Cl H H
CF3 H Ph-2-F-4-CF3 H H
CF3 H Ph-3-F-4-CF3 H H
CF3 H Ph-2-F-5-CF3 H H
CF3 H Ph-3-F-5-CF3 H H
CF3 H Ph-2-Cl-4-CF3 H H
CF3 H Ph-3,5-(CF3)2 H H
CF3 H Ph-3-Br-4-OCH3 H H
CF3 H Ph-3-F-4-OCHF2 H H
CF3 H Ph-3-Cl-4-OCHF2 H H
CF3 H Ph-3-Br-4-OCHF2 H H
CF3 H Ph-3-F-4-OCF3 H H
CF3 H Ph-3-Cl-4-OCF3 H H
CF3 H Ph-3-Br-4-OCF3 H H
CF3 H Ph-3-F-4-OCF2Br H H
CF3 H Ph-3-Cl-4-OCF2Br H H
CF3 H Ph-3-Br-4-OCF2Br H H
CF3 H Ph-3-F-4-OCF2CHF2 H H
CF3 H Ph-3-Cl-4-OCF2CHF2 H H
CF3 H Ph-3-Br-4-OCF2CHF2 H H
CF3 H Ph-3-F-4-OCF2CHFCl H H
CF3 H Ph-3-Cl-4-OCF2CHFCl H H
CF3 H Ph-3-Br-4-OCF2CHFCl H H
CF3 H Ph-3-F-4-OCF2CHFCF3 H H
CF3 H Ph-3-Cl-4-OCF2CHFCF3 H H
CF3 H Ph-3-Br-4-OCF2CHFCF3 H H
CF3 H Ph-3-F-4-OCF2CHFOCF3 H H
CF3 H Ph-3-Cl-4-OCF2CHFOCF3 H H
CF3 H Ph-3-Br-4-OCF2CHFOCF3 H H
CF3 H Ph-3-CH3-4-OCF2CHFOCF3 H H
CF3 H Ph-3-F-4-OCF2CHFOCF2CF2CF3 H H
CF3 H Ph-3-Cl-4-OCF2CHFOCF2CF2CF3 H H
CF3 H Ph-3-Br-4-OCF2CHFOCF2CF2CF3 H H
CF3 H Ph(-3-OCF2O-4-) H H
CF3 H Ph(-3-OCF2CF2O-4-) H H
CF3 H Ph-3-OPh-4-F H H
CF3 H Ph-3-NO2-4-F H H
CF3 H Ph-3-NO2-4-Cl H H
CF3 H Ph-2-F-5-NO2 H H
CF3 H Ph-3-CN-4-F H H
CF3 H Ph-2,3,4-F3 H H
CF3 H Ph-2,3,5-F3 H H
CF3 H Ph-2,4,5-F3 H H
CF3 H Ph-3,4,5-F3 H H
CF3 H Ph-2,3-F2-4-CH3 H H
CF3 H Ph-2,3-F2-4-CF3 H H
CF3 H Ph-3,4-F2-5-CF3 H H
CF3 H Ph-2-F-3-Cl-5-CF3 H H
CF3 H Ph-3,5-Cl2-4-OCH3 H H
CF3 H 1-Naph H H
CF3 H 2-Naph H H
CF3 H (L-1b)Br H H
CF3 H (L-1c)Cl H H
CF3 H (L-1c)Br H H
CF3 H (L-1c)I H H
CF3 H (L-1c)CF3 H H
CF3 H (L-2b)Br H H
CF3 H (L-3b)Cl H H
CF3 H (L-3b)Br H H
CF3 H (L-3c)F H H
CF3 H (L-3c)Cl H H
CF3 H (L-3c)Br H H
CF3 H (L-3c)I H H
CF3 H (L-3c)CF3 H H
CF3 H (L-3c)CN H H
CF3 H L-3d H H
CF3 H (L-4b)Cl H H
CF3 H (L-4b)Br H H
CF3 H (L-4b)CN H H
CF3 H (L-10b)Cl H H
CF3 H (L-10b)Br H H
CF3 H (L-15b)CF3 H H
CF3 H (L-16a)CHF2 H H
CF3 H (L-16a)CF2Br H H
CF3 H (L-17a)Cl H H
CF3 H (L-21b)Cl H H
CF3 H (L-21b)Br H H
CF3 H (L-21b)I H H
CF3 H (L-21b)CF3 H H
CF3 H (L-22b)Cl H H
CF3 H (L-22b)Br H H
CF3 H (L-23b)Cl H H
CF3 H (L-23b)Br H H
CF3 H (L-23c)Cl H H
CF3 H (L-23c)Br H H
CF3 H (L-31a)Cl H H
CF3 H (L-31a)Br H H
CF3 H (L-45c)F H H
CF3 H (L-45c)Cl H H
CF3 H (L-45c)Br H H
CF3 H (L-45c)I H H
CF3 H (L-45c)CF3 H H
CF3 H (L-45c)CF3 H CH3
CF3 H (L-45c)CF3 H Et
CF3 H (L-45c)CF3 H n-Pr
CF3 H (L-45c)CF3 H i-Pr
CF3 H (L-45c)CF3 H n-Bu
CF3 H (L-45c)CF3 H CH2CF3
CF3 H (L-45c)CF3 H CH2OCH3
CF3 H (L-45c)CF3 H CH2OEt
CF3 H (L-45c)CF3 H CH2SCH3
CF3 H (L-45c)CF3 H CH2CH=CH2
CF3 H (L-45c)CF3 H CH2CH=CF2
CF3 H (L-45c)CF3 H CH2CH=CCl2
CF3 H (L-45c)CF3 H CH2CF=CF2
CF3 H (L-45c)CF3 H CH2CCl=CCl2
CF3 H (L-45c)CF3 H CH2C≡CH
CF3 H (L-45c)CF3 H CH2Ph
CF3 H (L-45c)CF3 H Si(CH3)3
CF3 H (L-45c)CF3 H Si(CH3)2Bu-t
CF3 H (L-45c)CF3 H Si(CH3)2Ph
CF3 H L-45e H H
CF3 H L-45f H H
CF3 H (L-46c)F H H
CF3 H (L-46c)Cl H H
CF3 H (L-46c)Br H H
CF3 H (L-46c)I H H
CF3 H (L-46c)CF3 H H
CF3 H (L-46c)OCH2CF3 H H
CF3 H (L-46c)OCH(CF3)2 H H
CF3 H L-46d H H
CF3 H L-47a H H
CF3 H L-47d H H
CF3 H (L-48b)Br H H
CF3 H (L-50b)Cl H H
CF3 H (L-50b)Br H H
CF3 H (L-51b)Cl H H
CF3 -OCF2- H H
CF3 -OCF2- H CH3
CF3 -OCF2- H CH2OCH3
CF3 -OCF2- H Si(CH3)3
CF3 H -CF2O- H
CF3 H -CF2O- CH3
CF3 H -CF2O- CH2OCH3
CF3 H -CF2O- Si(CH3)3
CF2Cl H CF2O(Ph-4-Cl) H H
CF2Cl H CH=CH(Ph-4-Cl) H H
CF2Cl H CH=CH(Ph-4-OCF3) H H
CF2Cl H CH=CH(Ph-3,4-Cl2) H H
CF2Cl H Ph-4-F H H
CF2Cl H Ph-4-Cl H H
CF2Cl H Ph-4-Br H H
CF2Cl H Ph-4-I H H
CF2Cl H Ph-4-CF3 H H
CF2Cl H Ph-4-OCHF2 H H
CF2Cl H Ph-4-OCF3 H H
CF2Cl H Ph-4-OCF2Br H H
CF2Cl H Ph-4-OCF2CHF2 H H
CF2Cl H Ph-4-OCF2CHFCl H H
CF2Cl H Ph-4-OCF2CHFCF3 H H
CF2Cl H Ph-4-OCF2CHFOCF3 H H
CF2Cl H Ph-4-OCF2CHFOCF2CF2CF3 H H
CF2Cl H Ph-4-O(L-45g) H H
CF2Cl H Ph-3,4-Cl2 H H
CF2Cl H Ph(-3-OCF2O-4-) H H
CF2Cl H Ph(-3-OCF2CF2O-4-) H H
CF2Cl H (L-45c)Cl H H
CF2Cl H (L-45c)Br H H
CF2Cl H (L-45c)CF3 H H
CF2Cl H L-45e H H
CF2Cl H L-45f H H
CF2Cl H (L-46c)Cl H H
CF2Cl H (L-46c)Br H H
CF2Cl H (L-46c)CF3 H H
CF2Cl H L-46d H H
CFCl2 H Ph-4-OCF3 H H
CF2Br H Ph-4-Cl H H
CF2Br H Ph-4-Br H H
CF2Br H Ph-4-CF3 H H
CF2Br H Ph-4-OCF3 H H
CF2Br H Ph-4-OCF2Br H H
CF2Br H Ph-4-OCF2CHFCF3 H H
CF2Br H Ph-4-OCF2CHFOCF3 H H
CF2Br H Ph-4-OCF2CHFOCF2CF2CF3 H H
CF2Br H Ph-4-O(L-45g) H H
CF2Br H Ph-3,4-Cl2 H H
CF2Br H Ph(-3-OCF2O-4-) H H
CF2Br H Ph(-3-OCF2CF2O-4-) H H
CF2Br H (L-45c)CF3 H H
CF2Br H L-45f H H
CF2Br H (L-46c)CF3 H H
CF2Br H L-46d H H
CFClBr H (L-45c)CF3 H H
CFBr2 H Ph-4-Br H H
CF2CHF2 H Ph-4-CF3 H H
CF2CF3 H CF2O(Ph-4-Cl) H H
CF2CF3 H CH=CH(Ph-4-Cl) H H
CF2CF3 H CH=CH(Ph-4-OCF3) H H
CF2CF3 H CH=CH(Ph-3,4-Cl2) H H
CF2CF3 H Ph-4-F H H
CF2CF3 H Ph-4-Cl H H
CF2CF3 H Ph-4-Br H H
CF2CF3 H Ph-4-I H H
CF2CF3 H Ph-4-CF3 H H
CF2CF3 H Ph-4-OCHF2 H H
CF2CF3 H Ph-4-OCF3 H H
CF2CF3 H Ph-4-OCF2Br H H
CF2CF3 H Ph-4-OCF2CHF2 H H
CF2CF3 H Ph-4-OCF2CHFCl H H
CF2CF3 H Ph-4-OCF2CHFCF3 H H
CF2CF3 H Ph-4-OCF2CHFOCF3 H H
CF2CF3 H Ph-4-OCF2CHFOCF2CF2CF3 H H
CF2CF3 H Ph-4-O(L-45g) H H
CF2CF3 H Ph-3,4-Cl2 H H
CF2CF3 H Ph(-3-OCF2O-4-) H H
CF2CF3 H Ph(-3-OCF2CF2O-4-) H H
CF2CF3 H (L-45c)Cl H H
CF2CF3 H (L-45c)Br H H
CF2CF3 H (L-45c)CF3 H H
CF2CF3 H L-45e H H
CF2CF3 H L-45f H H
CF2CF3 H (L-46c)Cl H H
CF2CF3 H (L-46c)Br H H
CF2CF3 H (L-46c)CF3 H H
CF2CF3 H L-46d H H
CF2CF2Cl H Ph-4-OCF3 H H
CFClCF3 H (L-45c)CF3 H H
CFClCF2Cl H Ph-4-Br H H
CF2CF2Br H Ph-4-CF3 H H
CFBrCF3 H Ph-4-OCF3 H H
CF2CHFCF3 H (L-45c)CF3 H H
CF2CF2CF3 H Ph-4-Cl H H
CF2CF2CF3 H Ph-4-Br H H
CF2CF2CF3 H Ph-4-CF3 H H
CF2CF2CF3 H Ph-4-OCF3 H H
CF2CF2CF3 H Ph-4-OCF2Br H H
CF2CF2CF3 H Ph-4-OCF2CHFCF3 H H
CF2CF2CF3 H Ph-4-OCF2CHFOCF3 H H
CF2CF2CF3 H Ph-4-OCF2CHFOCF2CF2CF3 H H
CF2CF2CF3 H Ph-4-O(L-45g) H H
CF2CF2CF3 H Ph-3,4-Cl2 H H
CF2CF2CF3 H Ph(-3-OCF2O-4-) H H
CF2CF2CF3 H Ph(-3-OCF2CF2O-4-) H H
CF2CF2CF3 H (L-45c)CF3 H H
CF2CF2CF3 H L-45f H H
CF2CF2CF3 H (L-46c)CF3 H H
CF2CF2CF3 H L-46d H H
CF(CF3)2 H Ph-4-Br H H
CF2CFClCF2Cl H Ph-4-CF3 H H
CF2CFBrCF2Cl H Ph-4-OCF3 H H
CF2CF2CF2CHF2 H (L-45c)CF3 H H
CF2CF2CF2CF3 H Ph-4-Br H H
CF(CF3)CF2CF3 H Ph-4-CF3 H H
CF2CF2CF2CF2Cl H Ph-4-OCF3 H H
T-1 H (L-45c)CF3 H H
T-2 H Ph-4-Br H H
CF2OCH3 H Ph-4-Cl H H
CF2OCH3 H Ph-4-Br H H
CF2OCH3 H Ph-4-CF3 H H
CF2OCH3 H Ph-4-OCF3 H H
CF2OCH3 H Ph-4-OCF2Br H H
CF2OCH3 H Ph-4-OCF2CHFCF3 H H
CF2OCH3 H Ph-4-OCF2CHFOCF3 H H
CF2OCH3 H Ph-4-OCF2CHFOCF2CF2CF3 H H
CF2OCH3 H Ph-4-O(L-45g) H H
CF2OCH3 H Ph-3,4-Cl2 H H
CF2OCH3 H Ph(-3-OCF2O-4-) H H
CF2OCH3 H Ph(-3-OCF2CF2O-4-) H H
CF2OCH3 H (L-45c)CF3 H H
CF2OCH3 H L-45f H H
CF2OCH3 H (L-46c)CF3 H H
CF2OCH3 H L-46d H H
CF2SCH3 H Ph-4-Cl H H
CF2SCH3 H Ph-4-Br H H
CF2SCH3 H Ph-4-CF3 H H
CF2SCH3 H Ph-4-OCF3 H H
CF2SCH3 H Ph-4-OCF2Br H H
CF2SCH3 H Ph-4-OCF2CHFCF3 H H
CF2SCH3 H Ph-4-OCF2CHFOCF3 H H
CF2SCH3 H Ph-4-OCF2CHFOCF2CF2CF3 H H
CF2SCH3 H Ph-4-O(L-45g) H H
CF2SCH3 H Ph-3,4-Cl2 H H
CF2SCH3 H Ph(-3-OCF2O-4-) H H
CF2SCH3 H Ph(-3-OCF2CF2O-4-) H H
CF2SCH3 H (L-45c)CF3 H H
CF2SCH3 H L-45f H H
CF2SCH3 H (L-46c)CF3 H H
CF2SCH3 H L-46d H H
CF2SPr-n H Ph-4-CF3 H H
CF2SPr-i H Ph-4-OCF3 H H
―――――――――――――――――――――――――――――――――――――――
本発明化合物は、農園芸作物及び樹木などを加害する所謂農業害虫、家畜、家禽類に寄生する所謂家畜害虫、家屋等の人間の生活環境で様々な悪影響を与える所謂衛生害虫、倉庫に貯蔵された穀物等を加害する所謂貯穀害虫、及び同様の場面で発生、加害するダニ類、線虫類、軟体動物、甲殻類の何れの害虫も低濃度で有効に防除できる。 ―――――――――――――――――――――――――――――――――――――――
R 4 Y 2 R 5 Y 3 R 6
―――――――――――――――――――――――――――――――――――――――
CH 3 H CF 2 O (Ph-4-Cl) HH
CH 3 H CH = CH (Ph-4-Cl) HH
CH 3 H CH = CH (Ph-4-OCF 3 ) HH
CH 3 H CH = CH (Ph-3,4-Cl 2 ) HH
CH 3 H Ph-4-FHH
CH 3 H Ph-4-Cl HH
CH 3 H Ph-4-Br HH
CH 3 H Ph-4-IHH
CH 3 H Ph-4-CF 3 HH
CH 3 H Ph-4-OCHF 2 HH
CH 3 H Ph-4-OCF 3 HH
CH 3 H Ph-4-OCF 2 Br HH
CH 3 H Ph-4-OCF 2 CHF 2 HH
CH 3 H Ph-4-OCF 2 CHFCl HH
CH 3 H Ph-4-OCF 2 CHFCF 3 HH
CH 3 H Ph-4-OCF 2 CHFOCF 3 HH
CH 3 H Ph-4-OCF 2 CHFOCF 2 CF 2 CF 3 HH
CH 3 H Ph-4-O (L-45g) HH
CH 3 H Ph-3,4-Cl 2 HH
CH 3 H Ph (-3-OCF 2 O-4-) HH
CH 3 H Ph (-3-OCF 2 CF 2 O-4-) HH
CH 3 H (L-45c) Cl HH
CH 3 H (L-45c) Br HH
CH 3 H (L-45c) CF 3 HH
CH 3 H L-45e HH
CH 3 H L-45f HH
CH 3 H (L-46c) Cl HH
CH 3 H (L-46c) Br HH
CH 3 H (L-46c) CF 3 HH
CH 3 H L-46d HH
Et H CF 2 O (Ph-4-Cl) HH
Et H CH = CH (Ph-4-Cl) HH
Et H CH = CH (Ph-4-OCF 3 ) HH
Et H CH = CH (Ph-3,4-Cl 2 ) HH
Et H Ph-4-Cl HH
Et H Ph-4-Br HH
Et H Ph-4-CF 3 HH
Et H Ph-4-OCF 3 HH
Et H Ph-4-OCF 2 Br HH
Et H Ph-4-OCF 2 CHFCF 3 HH
Et H Ph-4-OCF 2 CHFOCF 3 HH
Et H Ph-4-OCF 2 CHFOCF 2 CF 2 CF 3 HH
Et H Ph-4-O (L-45g) HH
Et H Ph-3,4-Cl 2 HH
Et H Ph (-3-OCF 2 O-4-) HH
Et H Ph (-3-OCF 2 CF 2 O-4-) HH
Et H (L-45c) Br HH
Et H (L-45c) CF 3 HH
Et H L-45e HH
Et H L-45f HH
Et H (L-46c) Br HH
Et H (L-46c) CF 3 HH
Et H L-46d HH
n-Pr H Ph-4-Br HH
n-Pr H Ph-4-CF 3 HH
n-Pr H Ph-4-OCF 3 HH
n-Pr H (L-45c) CF 3 HH
i-Pr H Ph-4-Br HH
i-Pr H Ph-4-CF 3 HH
i-Pr H Ph-4-OCF 3 HH
i-Pr H (L-45c) CF 3 HH
c-Pr H Ph-4-Br HH
c-Pr H Ph-4-CF 3 HH
c-Pr H Ph-4-OCF 3 HH
c-Pr H (L-45c) CF 3 HH
n-Bu H Ph-4-Br HH
CH 2 FH Ph-4-CF 3 HH
CH 2 Cl H Ph-4-OCF 3 HH
CH 2 Br H (L-45c) CF 3 HH
CHF 2 H CF 2 O (Ph-4-Cl) HH
CHF 2 H CH = CH (Ph-4-Cl) HH
CHF 2 H CH = CH (Ph-4-OCF 3 ) HH
CHF 2 H CH = CH (Ph-3,4-Cl 2 ) HH
CHF 2 H Ph-4-FHH
CHF 2 H Ph-4-Cl HH
CHF 2 H Ph-4-Br HH
CHF 2 H Ph-4-IHH
CHF 2 H Ph-4-CF 3 HH
CHF 2 H Ph-4-OCHF 2 HH
CHF 2 H Ph-4-OCF 3 HH
CHF 2 H Ph-4-OCF 2 Br HH
CHF 2 H Ph-4-OCF 2 CHF 2 HH
CHF 2 H Ph-4-OCF 2 CHFCl HH
CHF 2 H Ph-4-OCF 2 CHFCF 3 HH
CHF 2 H Ph-4-OCF 2 CHFOCF 3 HH
CHF 2 H Ph-4-OCF 2 CHFOCF 2 CF 2 CF 3 HH
CHF 2 H Ph-4-O (L-45g) HH
CHF 2 H Ph-3,4-Cl 2 HH
CHF 2 H Ph (-3-OCF 2 O-4-) HH
CHF 2 H Ph (-3-OCF 2 CF 2 O-4-) HH
CHF 2 H (L-45c) Cl HH
CHF 2 H (L-45c) Br HH
CHF 2 H (L-45c) CF 3 HH
CHF 2 H L-45e HH
CHF 2 H L-45f HH
CHF 2 H (L-46c) Cl HH
CHF 2 H (L-46c) Br HH
CHF 2 H (L-46c) CF 3 HH
CHF 2 H L-46d HH
CHFCl H Ph-4-Br HH
CHFBr H Ph-4-CF 3 HH
CF 3 H CH 2 OCH 3 HH
CF 3 H CH 2 OEt HH
CF 3 H CH 2 OPr-n HH
CF 3 H CH 2 OPr-i HH
CF 3 H CH 2 OBu-n HH
CF 3 H CH 2 OCH 2 CF 3 HH
CF 3 H CH 2 OCH 2 CF 2 CF 3 HH
CF 3 H CH 2 OCH (CF 3 ) 2 HH
CF 3 H CH 2 OPh HH
CF 3 H CH 2 O (Ph-4-F) HH
CF 3 H CH 2 O (Ph-2-Cl) HH
CF 3 H CH 2 O (Ph-3-Cl) HH
CF 3 H CH 2 O (Ph-4-Cl) HH
CF 3 H CH 2 O (Ph-4-Br) HH
CF 3 H CH 2 O (Ph-4-CF 3 ) HH
CF 3 H CH 2 O (Ph-2-OCF 3 ) HH
CF 3 H CH 2 O (Ph-3-OCF 3 ) HH
CF 3 H CH 2 O (Ph-4-OCF 3 ) HH
CF 3 H CF 2 OPh HH
CF 3 H CF 2 O (Ph-3-F) HH
CF 3 H CF 2 O (Ph-4-F) HH
CF 3 H CF 2 O (Ph-2-Cl) HH
CF 3 H CF 2 O (Ph-3-Cl) HH
CF 3 H CF 2 O (Ph-4-Cl) HH
CF 3 H CF 2 O (Ph-3-Br) HH
CF 3 H CF 2 O (Ph-4-Br) HH
CF 3 H CF 2 O (Ph-3-CF 3 ) HH
CF 3 H CF 2 O (Ph-4-CF 3 ) HH
CF 3 H CF 2 O (Ph-3-OCF 3 ) HH
CF 3 H CF 2 O (Ph-4-OCF 3 ) HH
CF 3 H CH 2 SPh HH
CF 3 H CH 2 S (Ph-3-Cl) HH
CF 3 H CH 2 S (Ph-4-Cl) HH
CF 3 H CH 2 SO 2 (Ph-3-Cl) HH
CF 3 H CH 2 SO 2 (Ph-4-Cl) HH
CF 3 H CH 2 N (CH 3 ) 2 HH
CF 3 H CH 2 NHPh HH
CF 3 H CH 2 NH (Ph-3-Cl) HH
CF 3 H CH 2 NH (Ph-4-Cl) HH
CF 3 H CF 2 C (O) OEt HH
CF 3 H CH 2 (L-5a) HH
CF 3 H CH 2 (L-14a) HH
CF 3 H CH 2 (L-24a) HH
CF 3 H CH 2 (L-36a) HH
CF 3 HC (O) OEt HH
CF 3 HC (O) OBu-t HH
CF 3 HC (O) OCH 2 CF 3 HH
CF 3 H CH = CHPh HH
CF 3 H CH = CH (Ph-3-F) HH
CF 3 H CH = CH (Ph-4-F) HH
CF 3 H CH = CH (Ph-2-Cl) HH
CF 3 H CH = CH (Ph-3-Cl) HH
CF 3 H CH = CH (Ph-4-Cl) HH
CF 3 H CH = CH (Ph-3-Br) HH
CF 3 H CH = CH (Ph-4-Br) HH
CF 3 H CH = CH (Ph-3-CF 3 ) HH
CF 3 H CH = CH (Ph-4-CF 3 ) HH
CF 3 H CH = CH (Ph-3-OCF 3 ) HH
CF 3 H CH = CH (Ph-4-OCF 3 ) HH
CF 3 H CH = CH (Ph-3-SCH 3 ) HH
CF 3 H CH = CH (Ph-4-SCH 3 ) HH
CF 3 H CH = CH (Ph-3-SO 2 CH 3 ) HH
CF 3 H CH = CH (Ph-4-SO 2 CH 3 ) HH
CF 3 H CH = CH (Ph-3,4-F 2 ) HH
CF 3 H CH = CH (Ph-3-F-4-Cl) HH
CF 3 H CH = CH (Ph-3,4-Cl 2 ) HH
CF 3 H CH = CH (Ph-3,4-Br 2 ) HH
CF 3 H CH = CH (Ph-3-F-4-CF 3 ) HH
CF 3 H CH = CH (Ph-3-Cl-4-OCF 3 ) HH
CF 3 H CH = CH [Ph (-3-OCF 2 O-4-)] HH
CF 3 H Ph HH
CF 3 H Ph-2-FHH
CF 3 H Ph-3-FHH
CF 3 H Ph-4-FHH
CF 3 H Ph-2-Cl HH
CF 3 H Ph-3-Cl HH
CF 3 H Ph-4-Cl HH
CF 3 H Ph-3-Br HH
CF 3 H Ph-4-Br HH
CF 3 H Ph-4-Br H CH 3
CF 3 H Ph-4-Br H Et
CF 3 H Ph-4-Br H n-Pr
CF 3 H Ph-4-Br H i-Pr
CF 3 H Ph-4-Br H n-Bu
CF 3 H Ph-4-Br H CH 2 CF 3
CF 3 H Ph-4-Br H CH 2 OCH 3
CF 3 H Ph-4-Br H CH 2 OEt
CF 3 H Ph-4-Br H CH 2 SCH 3
CF 3 H Ph-4-Br H CH 2 CH = CH 2
CF 3 H Ph-4-Br H CH 2 CH = CF 2
CF 3 H Ph-4-Br H CH 2 CH = CCl 2
CF 3 H Ph-4-Br H CH 2 CF = CF 2
CF 3 H Ph-4-Br H CH 2 CCl = CCl 2
CF 3 H Ph-4-Br H CH 2 C≡CH
CF 3 H Ph-4-Br H CH 2 Ph
CF 3 H Ph-4-Br H Si (CH 3 ) 3
CF 3 H Ph-4-Br H Si (CH 3 ) 2 Bu-t
CF 3 H Ph-4-Br H Si (CH 3 ) 2 Ph
CF 3 H Ph-4-IHH
CF 3 H Ph-4-Bu-t HH
CF 3 H Ph-3-CF 3 HH
CF 3 H Ph-4-CF 3 HH
CF 3 H Ph-4-CF 3 H CH 3
CF 3 H Ph-4-CF 3 H Et
CF 3 H Ph-4-CF 3 H n-Pr
CF 3 H Ph-4-CF 3 H i-Pr
CF 3 H Ph-4-CF 3 H n-Bu
CF 3 H Ph-4-CF 3 H CH 2 CF 3
CF 3 H Ph-4-CF 3 H CH 2 OCH 3
CF 3 H Ph-4-CF 3 H CH 2 OEt
CF 3 H Ph-4-CF 3 H CH 2 SCH 3
CF 3 H Ph-4-CF 3 H CH 2 CH = CH 2
CF 3 H Ph-4-CF 3 H CH 2 CH = CF 2
CF 3 H Ph-4-CF 3 H CH 2 CH = CCl 2
CF 3 H Ph-4-CF 3 H CH 2 CF = CF 2
CF 3 H Ph-4-CF 3 H CH 2 CCl = CCl 2
CF 3 H Ph-4-CF 3 H CH 2 C≡CH
CF 3 H Ph-4-CF 3 H CH 2 Ph
CF 3 H Ph-4-CF 3 H Si (CH 3 ) 3
CF 3 H Ph-4-CF 3 H Si (CH 3 ) 2 Bu-t
CF 3 H Ph-4-CF 3 H Si (CH 3 ) 2 Ph
CF 3 H Ph-4-OCH 3 HH
CF 3 H Ph-4-OCHF 2 HH
CF 3 H Ph-3-OCF 3 HH
CF 3 H Ph-4-OCF 3 HH
CF 3 H Ph-4-OCF 3 H CH 3
CF 3 H Ph-4-OCF 3 H Et
CF 3 H Ph-4-OCF 3 H n-Pr
CF 3 H Ph-4-OCF 3 H i-Pr
CF 3 H Ph-4-OCF 3 H n-Bu
CF 3 H Ph-4-OCF 3 H CH 2 CF 3
CF 3 H Ph-4-OCF 3 H CH 2 OCH 3
CF 3 H Ph-4-OCF 3 H CH 2 OEt
CF 3 H Ph-4-OCF 3 H CH 2 SCH 3
CF 3 H Ph-4-OCF 3 H CH 2 CH = CH 2
CF 3 H Ph-4-OCF 3 H CH 2 CH = CF 2
CF 3 H Ph-4-OCF 3 H CH 2 CH = CCl 2
CF 3 H Ph-4-OCF 3 H CH 2 CF = CF 2
CF 3 H Ph-4-OCF 3 H CH 2 CCl = CCl 2
CF 3 H Ph-4-OCF 3 H CH 2 C≡CH
CF 3 H Ph-4-OCF 3 H CH 2 Ph
CF 3 H Ph-4-OCF 3 H Si (CH 3 ) 3
CF 3 H Ph-4-OCF 3 H Si (CH 3 ) 2 Bu-t
CF 3 H Ph-4-OCF 3 H Si (CH 3 ) 2 Ph
CF 3 H Ph-4-OCF 2 Br HH
CF 3 H Ph-4-OCH 2 CF 3 HH
CF 3 H Ph-4-OCF 2 CHF 2 HH
CF 3 H Ph-4-OCF 2 CHFCl HH
CF 3 H Ph-4-OCF 2 CHFBr HH
CF 3 H Ph-4-OCF 2 CF 2 Br HH
CF 3 H Ph-4-OCF 2 CFCl 2 HH
CF 3 H Ph-4-OCF 2 CCl 3 HH
CF 3 H Ph-4-OCH 2 CF 2 CHF 2 HH
CF 3 H Ph-3-OCF 2 CHFCF 3 HH
CF 3 H Ph-4-OCF 2 CHFCF 3 HH
CF 3 H Ph-4-OCH (CF 3 ) 2 HH
CF 3 H Ph-4-OCF 2 CFBrCF 3 HH
CF 3 H Ph-3-OCF 2 CHFOCF 3 HH
CF 3 H Ph-4-OCF 2 CHFOCF 3 HH
CF 3 H Ph-4-OCF 2 CHFOCF 2 CF 2 CF 3 HH
CF 3 H Ph-4-OSO 2 CH 3 HH
CF 3 H Ph-4-OSO 2 CF 3 HH
CF 3 H Ph-3-O (Ph-4-Cl) HH
CF 3 H Ph-4-O (Ph-4-Cl) HH
CF 3 H Ph-4-O (Ph-4-Br) HH
CF 3 H Ph-4-O (Ph-4-CF 3 ) HH
CF 3 H Ph-4-O (L-45c) Br HH
CF 3 H Ph-4-O (L-45c) CF 3 HH
CF 3 H Ph-3-O (L-45e) HH
CF 3 H Ph-4-O (L-45e) HH
CF 3 H Ph-4-O (L-48b) Br HH
CF 3 H Ph-4-SCH 3 HH
CF 3 H Ph-4-SO 2 CH 3 HH
CF 3 H Ph-3-S (Ph-4-Cl) HH
CF 3 H Ph-4-S (Ph-4-Cl) HH
CF 3 H Ph-4-S (Ph-4-Br) HH
CF 3 H Ph-4-S (Ph-4-CF 3 ) HH
CF 3 H Ph-4-S (L-45c) Br HH
CF 3 H Ph-4-S (L-45c) CF 3 HH
CF 3 H Ph-4-S (L-45e) HH
CF 3 H Ph-4-S (L-48b) Br HH
CF 3 H Ph-4-NO 2 HH
CF 3 H Ph-4-CN HH
CF 3 H Ph-2,3-F 2 HH
CF 3 H Ph-2,4-F 2 HH
CF 3 H Ph-3,4-F 2 HH
CF 3 H Ph-2,5-F 2 HH
CF 3 H Ph-3,5-F 2 HH
CF 3 H Ph-2-Cl-4-FHH
CF 3 H Ph-2-F-3-Cl HH
CF 3 H Ph-3-Cl-4-FHH
CF 3 H Ph-2-F-4-Cl HH
CF 3 H Ph-3-F-4-Cl HH
CF 3 H Ph-2,3-Cl 2 HH
CF 3 H Ph-2,4-Cl 2 HH
CF 3 H Ph-2,5-Cl 2 HH
CF 3 H Ph-3,4-Cl 2 HH
CF 3 H Ph-3,5-Cl 2 HH
CF 3 H Ph-3-Br-4-FHH
CF 3 H Ph-2-F-4-Br HH
CF 3 H Ph-2-F-5-Br HH
CF 3 H Ph-3,4-Br 2 HH
CF 3 H Ph-3,5-Br 2 HH
CF 3 H Ph-3-CH 3 -4-FHH
CF 3 H Ph-3-F-4-CH 3 HH
CF 3 H Ph-2-F-5-CH 3 HH
CF 3 H Ph-2,4- (CH 3 ) 2 HH
CF 3 H Ph-3,4- (CH 3 ) 2 HH
CF 3 H Ph-2-F-3-CF 3 HH
CF 3 H Ph-3-CF 3 -4-FHH
CF 3 H Ph-3-CF 3 -4-Cl HH
CF 3 H Ph-2-F-4-CF 3 HH
CF 3 H Ph-3-F-4-CF 3 HH
CF 3 H Ph-2-F-5-CF 3 HH
CF 3 H Ph-3-F-5-CF 3 HH
CF 3 H Ph-2-Cl-4-CF 3 HH
CF 3 H Ph-3,5- (CF 3 ) 2 HH
CF 3 H Ph-3-Br-4-OCH 3 HH
CF 3 H Ph-3-F-4-OCHF 2 HH
CF 3 H Ph-3-Cl-4-OCHF 2 HH
CF 3 H Ph-3-Br-4-OCHF 2 HH
CF 3 H Ph-3-F-4-OCF 3 HH
CF 3 H Ph-3-Cl-4-OCF 3 HH
CF 3 H Ph-3-Br-4-OCF 3 HH
CF 3 H Ph-3-F-4-OCF 2 Br HH
CF 3 H Ph-3-Cl-4-OCF 2 Br HH
CF 3 H Ph-3-Br-4-OCF 2 Br HH
CF 3 H Ph-3-F-4-OCF 2 CHF 2 HH
CF 3 H Ph-3-Cl-4-OCF 2 CHF 2 HH
CF 3 H Ph-3-Br-4-OCF 2 CHF 2 HH
CF 3 H Ph-3-F-4-OCF 2 CHFCl HH
CF 3 H Ph-3-Cl-4-OCF 2 CHFCl HH
CF 3 H Ph-3-Br-4-OCF 2 CHFCl HH
CF 3 H Ph-3-F-4-OCF 2 CHFCF 3 HH
CF 3 H Ph-3-Cl-4-OCF 2 CHFCF 3 HH
CF 3 H Ph-3-Br-4-OCF 2 CHFCF 3 HH
CF 3 H Ph-3-F-4-OCF 2 CHFOCF 3 HH
CF 3 H Ph-3-Cl-4-OCF 2 CHFOCF 3 HH
CF 3 H Ph-3-Br-4-OCF 2 CHFOCF 3 HH
CF 3 H Ph-3-CH 3 -4-OCF 2 CHFOCF 3 HH
CF 3 H Ph-3-F-4-OCF 2 CHFOCF 2 CF 2 CF 3 HH
CF 3 H Ph-3-Cl-4-OCF 2 CHFOCF 2 CF 2 CF 3 HH
CF 3 H Ph-3-Br-4-OCF 2 CHFOCF 2 CF 2 CF 3 HH
CF 3 H Ph (-3-OCF 2 O-4-) HH
CF 3 H Ph (-3-OCF 2 CF 2 O-4-) HH
CF 3 H Ph-3-OPh-4-FHH
CF 3 H Ph-3-NO 2 -4-FHH
CF 3 H Ph-3-NO 2 -4-Cl HH
CF 3 H Ph-2-F-5-NO 2 HH
CF 3 H Ph-3-CN-4-FHH
CF 3 H Ph-2,3,4-F 3 HH
CF 3 H Ph-2,3,5-F 3 HH
CF 3 H Ph-2,4,5-F 3 HH
CF 3 H Ph-3,4,5-F 3 HH
CF 3 H Ph-2,3-F 2 -4-CH 3 HH
CF 3 H Ph-2,3-F 2 -4-CF 3 HH
CF 3 H Ph-3,4-F 2 -5-CF 3 HH
CF 3 H Ph-2-F-3-Cl-5-CF 3 HH
CF 3 H Ph-3,5-Cl 2 -4-OCH 3 HH
CF 3 H 1-Naph HH
CF 3 H 2-Naph HH
CF 3 H (L-1b) Br HH
CF 3 H (L-1c) Cl HH
CF 3 H (L-1c) Br HH
CF 3 H (L-1c) IHH
CF 3 H (L-1c) CF 3 HH
CF 3 H (L-2b) Br HH
CF 3 H (L-3b) Cl HH
CF 3 H (L-3b) Br HH
CF 3 H (L-3c) FHH
CF 3 H (L-3c) Cl HH
CF 3 H (L-3c) Br HH
CF 3 H (L-3c) IHH
CF 3 H (L-3c) CF 3 HH
CF 3 H (L-3c) CN HH
CF 3 H L-3d HH
CF 3 H (L-4b) Cl HH
CF 3 H (L-4b) Br HH
CF 3 H (L-4b) CN HH
CF 3 H (L-10b) Cl HH
CF 3 H (L-10b) Br HH
CF 3 H (L-15b) CF 3 HH
CF 3 H (L-16a) CHF 2 HH
CF 3 H (L-16a) CF 2 Br HH
CF 3 H (L-17a) Cl HH
CF 3 H (L-21b) Cl HH
CF 3 H (L-21b) Br HH
CF 3 H (L-21b) IHH
CF 3 H (L-21b) CF 3 HH
CF 3 H (L-22b) Cl HH
CF 3 H (L-22b) Br HH
CF 3 H (L-23b) Cl HH
CF 3 H (L-23b) Br HH
CF 3 H (L-23c) Cl HH
CF 3 H (L-23c) Br HH
CF 3 H (L-31a) Cl HH
CF 3 H (L-31a) Br HH
CF 3 H (L-45c) FHH
CF 3 H (L-45c) Cl HH
CF 3 H (L-45c) Br HH
CF 3 H (L-45c) IHH
CF 3 H (L-45c) CF 3 HH
CF 3 H (L-45c) CF 3 H CH 3
CF 3 H (L-45c) CF 3 H Et
CF 3 H (L-45c) CF 3 H n-Pr
CF 3 H (L-45c) CF 3 H i-Pr
CF 3 H (L-45c) CF 3 H n-Bu
CF 3 H (L-45c) CF 3 H CH 2 CF 3
CF 3 H (L-45c) CF 3 H CH 2 OCH 3
CF 3 H (L-45c) CF 3 H CH 2 OEt
CF 3 H (L-45c) CF 3 H CH 2 SCH 3
CF 3 H (L-45c) CF 3 H CH 2 CH = CH 2
CF 3 H (L-45c) CF 3 H CH 2 CH = CF 2
CF 3 H (L-45c) CF 3 H CH 2 CH = CCl 2
CF 3 H (L-45c) CF 3 H CH 2 CF = CF 2
CF 3 H (L-45c) CF 3 H CH 2 CCl = CCl 2
CF 3 H (L-45c) CF 3 H CH 2 C≡CH
CF 3 H (L-45c) CF 3 H CH 2 Ph
CF 3 H (L-45c) CF 3 H Si (CH 3 ) 3
CF 3 H (L-45c) CF 3 H Si (CH 3 ) 2 Bu-t
CF 3 H (L-45c) CF 3 H Si (CH 3 ) 2 Ph
CF 3 H L-45e HH
CF 3 H L-45f HH
CF 3 H (L-46c) FHH
CF 3 H (L-46c) Cl HH
CF 3 H (L-46c) Br HH
CF 3 H (L-46c) IHH
CF 3 H (L-46c) CF 3 HH
CF 3 H (L-46c) OCH 2 CF 3 HH
CF 3 H (L-46c) OCH (CF 3 ) 2 HH
CF 3 H L-46d HH
CF 3 H L-47a HH
CF 3 H L-47d HH
CF 3 H (L-48b) Br HH
CF 3 H (L-50b) Cl HH
CF 3 H (L-50b) Br HH
CF 3 H (L-51b) Cl HH
CF 3 -OCF 2 -HH
CF 3 -OCF 2 -H CH 3
CF 3 -OCF 2 -H CH 2 OCH 3
CF 3 -OCF 2 -H Si (CH 3 ) 3
CF 3 H -CF 2 O- H
CF 3 H -CF 2 O- CH 3
CF 3 H -CF 2 O- CH 2 OCH 3
CF 3 H -CF 2 O- Si (CH 3 ) 3
CF 2 Cl H CF 2 O (Ph-4-Cl) HH
CF 2 Cl H CH = CH (Ph-4-Cl) HH
CF 2 Cl H CH = CH (Ph-4-OCF 3 ) HH
CF 2 Cl H CH = CH (Ph-3,4-Cl 2 ) HH
CF 2 Cl H Ph-4-FHH
CF 2 Cl H Ph-4-Cl HH
CF 2 Cl H Ph-4-Br HH
CF 2 Cl H Ph-4-IHH
CF 2 Cl H Ph-4-CF 3 HH
CF 2 Cl H Ph-4-OCHF 2 HH
CF 2 Cl H Ph-4-OCF 3 HH
CF 2 Cl H Ph-4-OCF 2 Br HH
CF 2 Cl H Ph-4-OCF 2 CHF 2 HH
CF 2 Cl H Ph-4-OCF 2 CHFCl HH
CF 2 Cl H Ph-4-OCF 2 CHFCF 3 HH
CF 2 Cl H Ph-4-OCF 2 CHFOCF 3 HH
CF 2 Cl H Ph-4-OCF 2 CHFOCF 2 CF 2 CF 3 HH
CF 2 Cl H Ph-4-O (L-45g) HH
CF 2 Cl H Ph-3,4-Cl 2 HH
CF 2 Cl H Ph (-3-OCF 2 O-4-) HH
CF 2 Cl H Ph (-3-OCF 2 CF 2 O-4-) HH
CF 2 Cl H (L-45c) Cl HH
CF 2 Cl H (L-45c) Br HH
CF 2 Cl H (L-45c) CF 3 HH
CF 2 Cl H L-45e HH
CF 2 Cl H L-45f HH
CF 2 Cl H (L-46c) Cl HH
CF 2 Cl H (L-46c) Br HH
CF 2 Cl H (L-46c) CF 3 HH
CF 2 Cl H L-46d HH
CFCl 2 H Ph-4-OCF 3 HH
CF 2 Br H Ph-4-Cl HH
CF 2 Br H Ph-4-Br HH
CF 2 Br H Ph-4-CF 3 HH
CF 2 Br H Ph-4-OCF 3 HH
CF 2 Br H Ph-4-OCF 2 Br HH
CF 2 Br H Ph-4-OCF 2 CHFCF 3 HH
CF 2 Br H Ph-4-OCF 2 CHFOCF 3 HH
CF 2 Br H Ph-4-OCF 2 CHFOCF 2 CF 2 CF 3 HH
CF 2 Br H Ph-4-O (L-45g) HH
CF 2 Br H Ph-3,4-Cl 2 HH
CF 2 Br H Ph (-3-OCF 2 O-4-) HH
CF 2 Br H Ph (-3-OCF 2 CF 2 O-4-) HH
CF 2 Br H (L-45c) CF 3 HH
CF 2 Br H L-45f HH
CF 2 Br H (L-46c) CF 3 HH
CF 2 Br H L-46d HH
CFClBr H (L-45c) CF 3 HH
CFBr 2 H Ph-4-Br HH
CF 2 CHF 2 H Ph-4-CF 3 HH
CF 2 CF 3 H CF 2 O (Ph-4-Cl) HH
CF 2 CF 3 H CH = CH (Ph-4-Cl) HH
CF 2 CF 3 H CH = CH (Ph-4-OCF 3 ) HH
CF 2 CF 3 H CH = CH (Ph-3,4-Cl 2 ) HH
CF 2 CF 3 H Ph-4-FHH
CF 2 CF 3 H Ph-4-Cl HH
CF 2 CF 3 H Ph-4-Br HH
CF 2 CF 3 H Ph-4-IHH
CF 2 CF 3 H Ph-4-CF 3 HH
CF 2 CF 3 H Ph-4-OCHF 2 HH
CF 2 CF 3 H Ph-4-OCF 3 HH
CF 2 CF 3 H Ph-4-OCF 2 Br HH
CF 2 CF 3 H Ph-4-OCF 2 CHF 2 HH
CF 2 CF 3 H Ph-4-OCF 2 CHFCl HH
CF 2 CF 3 H Ph-4-OCF 2 CHFCF 3 HH
CF 2 CF 3 H Ph-4-OCF 2 CHFOCF 3 HH
CF 2 CF 3 H Ph-4-OCF 2 CHFOCF 2 CF 2 CF 3 HH
CF 2 CF 3 H Ph-4-O (L-45g) HH
CF 2 CF 3 H Ph-3,4-Cl 2 HH
CF 2 CF 3 H Ph (-3-OCF 2 O-4-) HH
CF 2 CF 3 H Ph (-3-OCF 2 CF 2 O-4-) HH
CF 2 CF 3 H (L-45c) Cl HH
CF 2 CF 3 H (L-45c) Br HH
CF 2 CF 3 H (L-45c) CF 3 HH
CF 2 CF 3 H L-45e HH
CF 2 CF 3 H L-45f HH
CF 2 CF 3 H (L-46c) Cl HH
CF 2 CF 3 H (L-46c) Br HH
CF 2 CF 3 H (L-46c) CF 3 HH
CF 2 CF 3 H L-46d HH
CF 2 CF 2 Cl H Ph-4-OCF 3 HH
CFClCF 3 H (L-45c) CF 3 HH
CFClCF 2 Cl H Ph-4-Br HH
CF 2 CF 2 Br H Ph-4-CF 3 HH
CFBrCF 3 H Ph-4-OCF 3 HH
CF 2 CHFCF 3 H (L-45c) CF 3 HH
CF 2 CF 2 CF 3 H Ph-4-Cl HH
CF 2 CF 2 CF 3 H Ph-4-Br HH
CF 2 CF 2 CF 3 H Ph-4-CF 3 HH
CF 2 CF 2 CF 3 H Ph-4-OCF 3 HH
CF 2 CF 2 CF 3 H Ph-4-OCF 2 Br HH
CF 2 CF 2 CF 3 H Ph-4-OCF 2 CHFCF 3 HH
CF 2 CF 2 CF 3 H Ph-4-OCF 2 CHFOCF 3 HH
CF 2 CF 2 CF 3 H Ph-4-OCF 2 CHFOCF 2 CF 2 CF 3 HH
CF 2 CF 2 CF 3 H Ph-4-O (L-45g) HH
CF 2 CF 2 CF 3 H Ph-3,4-Cl 2 HH
CF 2 CF 2 CF 3 H Ph (-3-OCF 2 O-4-) HH
CF 2 CF 2 CF 3 H Ph (-3-OCF 2 CF 2 O-4-) HH
CF 2 CF 2 CF 3 H (L-45c) CF 3 HH
CF 2 CF 2 CF 3 H L-45f HH
CF 2 CF 2 CF 3 H (L-46c) CF 3 HH
CF 2 CF 2 CF 3 H L-46d HH
CF (CF 3 ) 2 H Ph-4-Br HH
CF 2 CFClCF 2 Cl H Ph-4-CF 3 HH
CF 2 CFBrCF 2 Cl H Ph-4-OCF 3 HH
CF 2 CF 2 CF 2 CHF 2 H (L-45c) CF 3 HH
CF 2 CF 2 CF 2 CF 3 H Ph-4-Br HH
CF (CF 3 ) CF 2 CF 3 H Ph-4-CF 3 HH
CF 2 CF 2 CF 2 CF 2 Cl H Ph-4-OCF 3 HH
T-1 H (L-45c) CF 3 HH
T-2 H Ph-4-Br HH
CF 2 OCH 3 H Ph-4-Cl HH
CF 2 OCH 3 H Ph-4-Br HH
CF 2 OCH 3 H Ph-4-CF 3 HH
CF 2 OCH 3 H Ph-4-OCF 3 HH
CF 2 OCH 3 H Ph-4-OCF 2 Br HH
CF 2 OCH 3 H Ph-4-OCF 2 CHFCF 3 HH
CF 2 OCH 3 H Ph-4-OCF 2 CHFOCF 3 HH
CF 2 OCH 3 H Ph-4-OCF 2 CHFOCF 2 CF 2 CF 3 HH
CF 2 OCH 3 H Ph-4-O (L-45g) HH
CF 2 OCH 3 H Ph-3,4-Cl 2 HH
CF 2 OCH 3 H Ph (-3-OCF 2 O-4-) HH
CF 2 OCH 3 H Ph (-3-OCF 2 CF 2 O-4-) HH
CF 2 OCH 3 H (L-45c) CF 3 HH
CF 2 OCH 3 H L-45f HH
CF 2 OCH 3 H (L-46c) CF 3 HH
CF 2 OCH 3 H L-46d HH
CF 2 SCH 3 H Ph-4-Cl HH
CF 2 SCH 3 H Ph-4-Br HH
CF 2 SCH 3 H Ph-4-CF 3 HH
CF 2 SCH 3 H Ph-4-OCF 3 HH
CF 2 SCH 3 H Ph-4-OCF 2 Br HH
CF 2 SCH 3 H Ph-4-OCF 2 CHFCF 3 HH
CF 2 SCH 3 H Ph-4-OCF 2 CHFOCF 3 HH
CF 2 SCH 3 H Ph-4-OCF 2 CHFOCF 2 CF 2 CF 3 HH
CF 2 SCH 3 H Ph-4-O (L-45g) HH
CF 2 SCH 3 H Ph-3,4-Cl 2 HH
CF 2 SCH 3 H Ph (-3-OCF 2 O-4-) HH
CF 2 SCH 3 H Ph (-3-OCF 2 CF 2 O-4-) HH
CF 2 SCH 3 H (L-45c) CF 3 HH
CF 2 SCH 3 H L-45f HH
CF 2 SCH 3 H (L-46c) CF 3 HH
CF 2 SCH 3 H L-46d HH
CF 2 SPr-n H Ph-4-CF 3 HH
CF 2 SPr-i H Ph-4-OCF 3 HH
―――――――――――――――――――――――――――――――――――――――
The compounds of the present invention are stored in so-called agricultural pests that harm agricultural and horticultural crops and trees, so-called livestock pests parasitic on livestock and poultry, so-called sanitary pests that cause various adverse effects in human living environments such as houses, and warehouses. It is possible to effectively control low-concentration pests such as so-called stored-grain pests that harm cereals and the like, and mite, nematodes, molluscs, and crustaceans that occur and harm in similar situations.

本発明化合物を用いて防除しうる昆虫類、ダニ類、線虫類、軟体動物及び甲殻類には具体的に、例えば、
コナガ(Plutella xylostella)、タマナヤガ(Agrotis ipsilon)、カブラヤガ(Agrotis segetum)、オオタバコガ(Helicoverpa armigera)、タバコガ(Helicoverpa assulta)、コットンボールワーム(Helicoverpa zea)、タバコバッドワーム(Heliothis virescens)、ヨトウガ(Mamestra brassicae)、フタオビコヤガ(Naranga aenescens)、タマナギンウワバ(Plusia nigrisigna)、アワヨトウ(Pseudaletia separata)、シロイチモジヨトウ(Spodoptera exigua)、ハスモンヨトウ(Spodoptera litura)、コットンリーフワーム(Spodoptera littoralis)、フォールアーミーワーム(Spodoptera frugiperda)、サザンアーミーワーム(Spodoptera eridania)、トマトホーンワーム(Manduca quinquemaculata)、タバコホーンワーム(Manduca sexta)、グレープベリーモス(Endopiza viteana)、ギンモンハモグリガ(Lyonetia prunifoliella malinella)、キンモンホソガ(Phyllonorycter ringoneella)、ミカンハモグリガ(Phyllocnistis citrella)、ワタアカミムシ(Pectinophora gossypiella)、モモシンクイガ(Carposina niponensis)、リンゴコカクモンハマキ(Adoxophyes orana faciata)、チャノコカクモンハマキ(Adoxophyes honmai)、チャハマキ(Homona magnamina)、コドリンガ(Cydla pomonella)、ナシヒメシンクイ(Grapholita molesta)、ニカメイガ(Chilo suppressalis)、コブノメイガ(Cnaphalocrocis medinalis)、ハイマダラノメイガ(Hellula undalis)、ヨーロピアンコーンボーラー(Ostrinia nubilalis)、ソイビーンルーパー(Pseudoplusia includens)、イラクサギンウワバ(Trichoplusia ni)、アメリカシロヒトリ(Hyphantria cunea)、モンシロチョウ(Pieris rapae crucivora)、イチモンジセセリ(Parnara guttata)等の鱗翅目害虫、
ドウガネブイブイ(Anomala cuprea)、ヒメコガネ(Anomala rufocuprea)、マメコガネ(Popillia japonica)、コロラドポテトビートル(Lepinotarsa decemlineata)、インゲンテントウ(Epilachna varivestis)、カンシャクシコメツキ(Melanotus tamsuyensis)、タバコシバンムシ(Lasioderma serricorne)、ヒメヒラタケシキスイ(Epuraea domina)、ニジュウヤホシテントウ(Henosepilachna vigintioctopunctata)、チャイロコメノゴミムシダマシ(Tenebrio molitor)、コクヌストモドキ(Tribolium castaneum)、ゴマダラカミキリ(Anoplophora malasiaca)、マツノマダラカミキリ(Monochamus alternatus)、アズキゾウムシ(Callosobruchus chinensis)、ウリハムシ(Aulacophora femoralis)、イネドロオイムシ(Oulema oryzae)、キスジノミハムシ(Phyllotreta striolata)、アリモドキゾウムシ(Cylas formicarius)、ワタミゾウムシ(Anthonomus grandis)、イネゾウムシ(Ethinocnemus squameus)、アルファルファタコゾウムシ(Hypera postica)、イネミズゾウムシ(Lissorhoptrus oryzophilus)、コクゾウ(Sitophilus zeamais)、シバオサゾウムシ(Sphenophrus venatus vestius)、グラナリーウィービル(Sitophilus granarius)、サザンコーンルートワーム(Diabrotica undecimpunctata)、ウエスタンコーンルートワーム(Diabrotica virgifera)、ノーザンコーンルートワーム(Diabrotica barberi)、アオバアリガタハネカクシ(Paederus fuscipes)等の鞘翅目害虫、
ナガメ(Eurydema rugosa)、シラホシカメムシ(Eysarcoris ventralis)、クサギカメムシ(Halyomorpha mista)、ミナミアオカメムシ(Nezara viridula)、クモヘリカメムシ(Leptocorisa chinensis)、ホソヘリカメムシ(Riptortus clavatus)、コバネヒョウタンナガカメムシ(Togo hemipterus)、ターニッシュドプラントバグ(Lygus lineolaris)、コットンフリーホッパー(Psuedatomoscelis seriatus)、ツツジグンバイ(Stephanitis pyrioides)、フタテンオオヨコバイ(Epiacanthus stramineus)、チャノミドリヒメヨコバイ(Empoasca onukii)、ポテトリーフホッパー(Empoasca fabae)、ツマグロヨコバイ(Nephotettix cinctinceps)、ヒメトビウンカ(Laodelphax striatellus)、トビイロウンカ(Nilaparvata lugens)、セジロウンカ(Sogatella furcifera)、ミカンキジラミ(Trioza erytreae)、ナシキジラミ(Psylla pyrisuga)、シルバーリーフコナジラミ(Bemisia argentifolii)、タバココナジラミ(Bemisia tabaci)、ミカンコナジラミ(Dialeurodes citri)、オンシツコナジラミ(Trialeurodes vaporariorum)、ワタアブラムシ(Aphis gossypii)、ユキヤナギアブラムシ(Aphis pomi)、モモアカアブラムシ(Myzus persicae)、オオワラジカイガラムシ(Drosicha corpulenta)、イセリアカイガラムシ(Icerya purchasi)、ミカンコナカイガラムシ(Planococcus citri)、クワコナカイガラムシ(Pseudococcus comstocki)、ルビーロウムシ(Ceroplastes rubens)、ヤノネカイガラムシ(Unaspis yanonensis)、トコジラミ(Cimex lectularius)等の半翅目害虫、
ミカンキイロアザミウマ(Frankliniella occidentalis)、ヒラズハナアザミウマ(Frankliniella intonsa)、チャノキイロアザミウマ(Scirtothrips dorsalis)、ミナミキイロアザミウマ(Thrips palmi)、ネギアザミウマ(Thrips tabaci)等の総翅目害虫、
ミカンコミバエ(Dacus dorsalis)、ウリミバエ(Dacus cucurbitae)、チチュウカイミバエ(Ceratitis capitata)、イネヒメハモグリバエ(Hydrellia griseola)、ナスハモグリバエ(Liriomyza bryoniae)、マメハモグリバエ(Liriomyza trifolii)、タネバエ(Hylemya platura)、アップルマゴット(Rhagoletis pomonella)、ヘシアンフライ(Mayetiola destructor)、イエバエ(Musca domestica)、サシバエ(Stomoxys calcitrans)、ヒツジシラミバエ(Melophagus ovinus)、ウシバエ(Hypoderma bovis)、キスジウシバエ(Hypoderma lineatum)、ヒツジバエ(Oestrus ovis)、ツェツェバエ(Glossina palpalis, Glossina morsitans)、キアシオオブユ(Prosimulium yezoensis)、ウシアブ(Tabanus trigonus)、オオチョウバエ(Telmatoscopus albipunctatus)、トクナガヌカカ(Leptoconops nipponensis)、アカイエカ(Culex pipiens pallens)、ネッタイシマカ(Aedes aegypti)、ヒトスジシマカ(Aedes albopicutus)、シナハマダラカ(Anopheles hyracanus sinesis)等の双翅目害虫、
クリハバチ(Apethymus kuri)、カブラハバチ(Athalia rosae japonensis)、マツノキハバチ(Neodiprion sertifer)、グンタイアリ(Eciton burchelli, Eciton schmitti)、クロオオアリ(Camponotus japonicus)、オオスズメバチ(Vespa mandarina)、ブルドックアント(Myrmecia spp.)、ファイヤーアント類(Solenopsis spp.)、ファラオアント(Monomorium pharaonis)等の膜翅目害虫、
クロゴキブリ(Periplaneta fuliginosa)、ヤマトゴキブリ(Periplaneta japonica)、チャバネゴキブリ(Blattella germanica)等の網翅目害虫、
エンマコオロギ(Teleogryllus emma)、ケラ(Gryllotalpa africana)、トノサマバッタ(Locusta migratoria)、コバネイナゴ(Oxya yezoensis)、サバクワタリバッタ(Schistocerca gregaria)等の直翅目害虫、
イエシロアリ(Coptotermes formosanus)、ヤマトシロアリ(Reticulitermes speratus)、タイワンシロアリ(Odontotermes formosanus)等のシロアリ目害虫、
ネコノミ(Ctenocephalidae felis)、ヒトノミ(Pulex irritans)、ケオプスネズミノミ(Xenopsylla cheopis)等の等翅目害虫、
ニワトリオオハジラミ(Menacanthus stramineus)、ウシハジラミ(Bovicola bovis)等のハジラミ目害虫、
ウシジラミ(Haematopinus eurysternus)、ブタジラミ(Haematopinus suis)、ウシホソジラミ(Linognathus vituli)、ケブカウシジラミ(Solenopotes capillatus)等のシラミ目害虫、
ミカンハダニ(Panonychus citri)、リンゴハダニ(Panonychus ulmi)、カンザワハダニ(Tetranychus kanzawai)、ナミハダニ(Tetranychus urticae)等のハダニ類、
チャノナガサビダニ(Acaphylla theae)、ミカンサビダニ(Aculops pelekassi)、ニセナシサビダニ(Eriophyes chibaensis)、チューリップサビダニ(Aceria tulipae)等のフシダニ類、
チャノホコリダニ(Polyphaotarsonemus latus)、シクラメンホコリダニ(Steneotarsonemus pallidus)等のホコリダニ類、
ケナガコナダニ(Tyrophagus putrescentiae)、ロビンネダニ(Rhizoglyphus robini)等のコナダニ類、
ミツバチヘギイタダニ(Varroa jacobsoni)等のハチダニ類、
オウシマダニ(Boophilus microplus)、フタトゲチマダニ(Haemaphysalis longicornis)等のマダニ類、
ヒツジキュウセンダニ(Psoroptes ovis)等のキュウセンダニ類、
ヒゼンダニ(Sarcoptes scabiei)等のヒゼンダニ類、
オカダンゴムシ(Armadillidium vulgare)等の甲殻類、
キタネグサレセンチュウ(Prathylenchus penetrans)、クルミネグサレセンチュウ(Prathylenchus vulnus)、ジャガイモシストセンチュウ(Globodera rostochiensis)、ダイズシストセンチュウ(Heterodera glycines)、キタネコブセンチュウ(Meloidogyne hapla)、サツマイモネコブセンチュウ(Meloidogyne incognita)、マツノザイセンチュウ(Bursaphelenchus lignicolus)等の線虫類、
スクミリンゴガイ(Ponacea canaliculata)、ナメクジ(Incilaria bilineata)、ウスカワマイマイ(Acusta despecta sieboldiana)、ミスジマイマイ(Euhadra peliomphala)等の軟体動物、
等が挙げられるが、本発明はこれらのみに限定されるものではない。 Specific examples of insects, mites, nematodes, molluscs and crustaceans that can be controlled using the compounds of the present invention include, for example,
Plutella xylostella, Agrotis ipsilon, Agrotis segetum, Helicoverpa armigera, Tobacco moth (Helicoverpa zea), Cotton ball worm (Helicoverpa zea), Tobacco budworm (Heliothis virescens) ), Naranga aenescens, Plusia nigrisigna, Pseudaletia separata, Spodoptera exigua, Spodoptera litura, Spodoptera litura, pod worm Worm (Spodoptera eridania), Tomato horn worm (Manduca quinquemaculata), Tobacco horn worm (Manduca sexta), Grapeberry moss (Endopiza viteana), Ginmon peach moth (Lyonetia prunifoliella malinella), Kinmonhosoga (Phyllonorycter ringone moth) llocnistis citrella), cotton beetle (Pectinophora gossypiella), peach scallop (Carposina niponensis), apple wolfberry (Adoxophyes orana faciata), tea wolfberry (Adoxophyes honmai), chadki (Homona magnamina), ydla molesta, Chilo suppressalis, Cnaphalocrocis medinalis, Hellula undalis, European corn borer (Ostrinia nubilalis), Soybean looper (Pseudoplusia includens), Irrigating tribe (Trichoplusia nitriphan) cunea), Lepidoptera (Pieris rapae crucivora), Lepidoptera (Parnara guttata) and other Lepidoptera pests,
Douganebubui (Anomala cuprea), Japanese beetle (Anomala rufocuprea), Japanese beetle (Popillia japonica), Colorado potato beetle (Lepinotarsa decemlineata), Common beetle (Epilachna varivestis), Japanese horned beetle (Melanotus ramsu) Pepper (Epuraea domina), Henosepilachna vigintioctopunctata, Tenebrio molitor, Tribobrium castaneum, Monchorus turkey ), Leaf beetle (Aulacophora femoralis), rice beetle (Oulema oryzae), Phyllotreta striolata, Cylas formicarius, cotton weevil (Anthonomus grandis), rice weevil (Ethinocnemus squa) Alfata weevil (Hypera postica), rice weevil (Lissorhoptrus oryzophilus), hornbill (Sitophilus zeamais), hornet weevil (Sphenophrus venatus vestius), granary weevil (Sitophilus granarius), Southern corn root worm (Diabata ica) Crustacea pests such as root worms (Diabrotica virgifera), Northern corn root worms (Diabrotica barberi), Aobaarigatatae (Paederus fuscipes),
Sea turtle (Eurydema rugosa), White-headed bug (Eysarcoris ventralis), White-headed bug (Halyomorpha mista), Southern stink bug (Nezara viridula), Spider-headed bug (Leptocorisa chinensis), White-headed bug (Riptortus clam) hemipterus), tarnished plant bug (Lygus lineolaris), cotton-free hopper (Psuedatomoscelis seriatus), azalea (Stephanitis pyrioides), butterfly (Epiacanthus stramineus), tea-nosed leafhopper (Empoasca onukii), potato leaf Empoasca fabae), leafhopper leafhopper (Nephotettix cinctinceps), brown leafhopper (Laodelphax striatellus), leafhopper (Nilaparvata lugens), white leafhopper (Sogatella furcifera), leafworm (Trioza erytreae), leafworm (Trioza erytreae) Bemisia tabaci, Dialeurodes citri, Trialeurodes vaporariorum, Cotton aphid (Aphis gossypii), Aphis pomi, Myphis persicae, Icha pula Scale insects (Icerya purchasi), citrus scale insects (Planococcus citri), scallop scale insects (Pseudococcus comstocki), ruby beetle (Ceroplastes rubens), hornworm scale insects (Unaspis yanonensis), insect lice (Cimex lectularius), etc.
Thrips palma, Thrips tabaci, Thrips tabaci, Thrips tabaci, Thrips tabaci, Thrips tabaci
Drosophila (Dacus dorsalis), Drosophila (Dacus cucurbitae), Drosophila fruit fly (Ceratitis capitata), Green leaf fly (Hydrellia griseola), Drosophila flyfly (Liriomyza bryoniae), Larimyza flies (Liriomyza flies) pomonella, fly Hessian (Mayetiola destructor), housefly (Musca domestica), flies (Stomoxys calcitrans), sheep flies (Melophagus ovinus), bullflies (Hypoderma bovis), dwarf flies (Hypoderma lineatum), opalese vis , Glossina morsitans), Prosimulium yezoensis, cattle fly (Tabanus trigonus), giant fly (Telmatoscopus albipunctatus), red-footed hawk (Leptoconops nipponensis), Acacia (Culex pipiens pallens), Laka (Anopheles hyracanus sinesis) Diptera pests such as,
Bumblebee (Apethymus kuri), Bumblebee (Athalia rosae japonensis), Bumblebee (Neodiprion sertifer), Guntai ant (Eciton burchelli, Eciton schmitti), Black-headed ant (Camponotus japonicus), Mysticia sp. (Solenopsis spp.), Pharaoh ant (Monomorium pharaonis), etc.
Reticulate pests such as black cockroach (Periplaneta fuliginosa), cockroach (Periplaneta japonica), German cockroach (Blattella germanica),
Straight insect pests such as telegryllus emma, kerat (Gryllotalpa africana), locust migratoria, loxta yezoensis, mackerel grasshopper (Schistocerca gregaria),
Termite insect pests such as termites (Coptotermes formosanus), Yamato termites (Reticulitermes speratus), Thai termites (Odontotermes formosanus),
Pesticides such as cat fleas (Ctenocephalidae felis), human fleas (Pulex irritans), and keops mouse fleas (Xenopsylla cheopis),
White-eye pests such as chicken lice (Menacanthus stramineus) and bovine lice (Bovicola bovis),
Lice insect pests such as cattle lice (Haematopinus eurysternus), pig lice (Haematopinus suis), cattle white lice (Linognathus vituli), horned lice (Solenopotes capillatus),
Spider mites (Panonychus citri), apple spider mite (Panonychus ulmi), Kanzawa spider mite (Tetranychus kanzawai), spider mites (Tetranychus urticae), etc.
Acarphylla theae, Scarlet mite (Aculops pelekassi), Scarlet mite (Eriophyes chibaensis), Tulip mite (Aceria tulipae), etc.
Dust mites such as tea dust mite (Polyphaotarsonemus latus), cyclamen dust mite (Steneotarsonemus pallidus),
Acarid mites (Tyrophagus putrescentiae), Robin mite (Rhizoglyphus robini),
Bee mites such as honeybee mite (Varroa jacobsoni),
Ticks, such as the tick (Boophilus microplus), the spider tick (Haemaphysalis longicornis),
Cucumber mites such as sheep cucumber mites (Psoroptes ovis),
Spider mites such as Scaroptes scabiei,
Crustaceans, such as Armadillidium vulgare,
Red-bellied nematode (Prathylenchus penetrans), Kurumi-gure-saenchu (Prathylenchus vulnus), Potato-cyst nematode (Globodera rostochiensis), Soybean-cyst nematode (Heterodera glycines), Red-tailed nematode Nematodes such as (Bursaphelenchus lignicolus),
Mollusks such as Ponacea canaliculata, slug (Incilaria bilineata), Austa despecta sieboldiana, Mishaimai (Euhadra peliomphala),
However, the present invention is not limited to these examples.

さらに、本発明化合物は、有機燐系化合物、カーバメート系化合物又はピレスロイド系化合物等の既存の殺虫剤に対して抵抗性の発達した害虫に対しても有効である。   Furthermore, the compound of the present invention is also effective against pests that have developed resistance to existing insecticides such as organophosphorus compounds, carbamate compounds, and pyrethroid compounds.

すなわち、本発明化合物は、直翅目、アザミウマ目、半翅目、鱗翅目、鞘翅目、膜翅目、双翅目、網翅目、等翅目、シロアリ目、ダニ・シラミ類及び線虫類の害虫を低濃度で有効に防除することが出来る。一方、本発明化合物はホ乳類、魚類、甲殻類及び益虫に対してほとんど悪影響の無い極めて有用な特長を有している。   That is, the compounds of the present invention are: Diptera, Thripidae, Hemiptera, Lepidoptera, Coleoptera, Hymenoptera, Diptera, Reticulates, Isoptera, Termites, Mites, Lice and Nematodes It is possible to effectively control the insect pests at a low concentration. On the other hand, the compounds of the present invention have extremely useful features that have almost no adverse effects on mammals, fish, crustaceans and beneficial insects.

本発明化合物を使用するにあたっては、通常適当な固体担体又は液体担体と混合し、更に所望により界面活性剤、浸透剤、展着剤、増粘剤、凍結防止剤、結合剤、固結防止剤、崩壊剤、消泡剤、防腐剤および分解防止剤等を添加して、液剤（soluble concentrate）、乳剤（emulsifiable concentrate）、水和剤（wettable powder）、水溶剤（water soluble powder）、顆粒水和剤（water dispersible granule）、顆粒水溶剤（water soluble granule）、懸濁剤（suspension concentrate）、乳濁剤（concentrated emulsion）、サスポエマルジョン（suspoemulsion）、マイクロエマルジョン（microemulsion）、粉剤（dustable powder）、粒剤（granule）錠剤（tablet）および乳化性ゲル剤（emulsifiable gel）等任意の剤型の製剤にて実用に供することができる。また、省力化および安全性向上の観点から、上記任意の剤型の製剤を、水溶性カプセルおよび水溶性フィルムの袋等の水溶性包装体に封入して供することもできる。   When using the compound of the present invention, it is usually mixed with a suitable solid carrier or liquid carrier, and if desired, a surfactant, penetrant, spreading agent, thickener, antifreezing agent, binder, anti-caking agent. , Disintegrating agents, antifoaming agents, preservatives and anti-degradation agents, etc., and soluble concentrate, emulsion (emulsifiable concentrate), wettable powder, water-soluble powder, granular water Water dispersible granule, water soluble granule, suspension concentrate, concentrated emulsion, suspoemulsion, microemulsion, dustable powder ), Granule tablets, and emulsifiable gels, and can be put to practical use. Further, from the viewpoint of labor saving and safety improvement, the preparations of any of the above dosage forms can be provided by being enclosed in a water-soluble package such as a water-soluble capsule and a bag of a water-soluble film.

固体担体としては、例えば石英、方解石、海泡石、ドロマイト、チョーク、カオリナイト、パイロフィライト、セリサイト、ハロサイト、メタハロサイト、木節粘土、蛙目粘土、陶石、ジークライト、アロフェン、シラス、きら、タルク、ベントナイト、活性白土、酸性白土、軽石、アタパルジャイト、ゼオライトおよび珪藻土等の天然鉱物質、例えば焼成クレー、パーライト、シラスバルーン、バーミキュライト、アタパルガスクレーおよび焼成珪藻土等の天然鉱物質の焼成品、例えば炭酸マグネシウム、炭酸カルシウム、炭酸ナトリウム、炭酸水素ナトリウム、硫酸アンモニウム、硫酸ナトリウム、硫酸マグネシウム、リン酸水素二アンモニウム、リン酸二水素アンモニウムおよび塩化カリウム等の無機塩類、例えばブドウ糖、果糖、しょ糖および乳糖などの糖類、例えば澱粉、粉末セルロースおよびデキストリン等の多糖類、例えば尿素、尿素誘導体、安息香酸および安息香酸の塩等の有機物、例えば木粉、コルク粉、トウモロコシ穂軸、クルミ殻およびタバコ茎等の植物類、フライアッシュ、ホワイトカーボン（例えば、含水合成シリカ、無水合成シリカおよび含水合成シリケート等）ならびに肥料等が挙げられる。   Examples of the solid carrier include quartz, calcite, gypsum, dolomite, chalk, kaolinite, pyrophyllite, sericite, halosite, metahalosite, kibushi clay, glazed clay, porcelain stone, siegrite, and allophane. Natural minerals such as shirasu, kira, talc, bentonite, activated clay, acid clay, pumice, attapulgite, zeolite and diatomaceous earth, for example, calcined clay, perlite, shirasu balloon, vermiculite, attapulgus clay and calcined diatomaceous earth Baked products such as magnesium carbonate, calcium carbonate, sodium carbonate, sodium bicarbonate, ammonium sulfate, sodium sulfate, magnesium sulfate, diammonium hydrogen phosphate, ammonium dihydrogen phosphate and potassium chloride, such as glucose, fructose , And Saccharides such as sugar and lactose, polysaccharides such as starch, powdered cellulose and dextrin, organic materials such as urea, urea derivatives, benzoic acid and benzoic acid salts, such as wood flour, cork flour, corn cob, walnut shell and Examples include plants such as tobacco stalks, fly ash, white carbon (for example, hydrous synthetic silica, anhydrous synthetic silica, hydrous synthetic silicate, etc.) and fertilizers.

液体担体としては、例えばキシレン、アルキル（Ｃ9またはＣ10等）ベンゼン、フェニルキシリルエタンおよびアルキル（Ｃ1またはＣ3等）ナフタレン等の芳香族炭化水素類、マシン油、ノルマルパラフィン、イソパラフィンおよびナフテン等の脂肪族炭化水素類、ケロシン等の芳香族炭化水素と脂肪族炭化水素の混合物、エタノール、イソプロパノール、シクロヘキサノール、フェノキシエタノールおよびベンジルアルコール等のアルコール、エチレングリコール、プロピレングリコール、ジエチレングリコール、ヘキシレングリコール、ポリエチレングリコールおよびポリプロピレングリコール等の多価アルコール、プロピルセロソルブ、ブチルセロソルブ、フェニルセロソルブ、プロピレングリコールモノメチルエーテル、プロピレングリコールモノエチルエーテル、プロピレングリコールモノプロピルエーテル、プロピレングリコールモノブチルエーテルおよびプロピレングリコールモノフェニルエーテル等のエーテル、アセトフェノン、シクロヘキサノンおよびγ−ブチロラクトン等のケトン、脂肪酸メチルエステル、コハク酸ジアルキルエステル、グルタミン酸ジアルキルエステル、アジピン酸ジアルキルエステルおよびフタル酸ジアルキルエステル等のエステル、Ｎ−アルキル（Ｃ1、Ｃ8またはＣ12等）ピロリドン等の酸アミド、大豆油、アマニ油、ナタネ油、ヤシ油、綿実油およびヒマシ油等の油脂、ジメチルスルホキシドならびに水が挙げられる。 Examples of the liquid carrier include xylene, alkyl (C 9 or C 10 etc.) benzene, phenyl xylyl ethane and alkyl (C 1 or C 3 etc.) naphthalene and other aromatic hydrocarbons, machine oil, normal paraffin, isoparaffin and Aliphatic hydrocarbons such as naphthene, mixtures of aromatic and aliphatic hydrocarbons such as kerosene, alcohols such as ethanol, isopropanol, cyclohexanol, phenoxyethanol and benzyl alcohol, ethylene glycol, propylene glycol, diethylene glycol, hexylene glycol , Polyhydric alcohols such as polyethylene glycol and polypropylene glycol, propyl cellosolve, butyl cellosolve, phenyl cellosolve, propylene glycol monomethyl ether, propylene Ethers such as recall monoethyl ether, propylene glycol monopropyl ether, propylene glycol monobutyl ether and propylene glycol monophenyl ether, ketones such as acetophenone, cyclohexanone and γ-butyrolactone, fatty acid methyl esters, dialkyl esters of succinic acid, dialkyl esters of glutamic acid, adipine esters such as dialkyl ester and dialkyl phthalate esters, N- alkyl (C 1, C 8 or C 12, etc.) acid amide pyrrolidone, soybean oil, linseed oil, rapeseed oil, coconut oil, such as cottonseed oil and castor oil Examples include fats and oils, dimethyl sulfoxide and water.

これら固体および液体担体は、単独で用いても２種以上を併用してもよい。   These solid and liquid carriers may be used alone or in combination of two or more.

界面活性剤としては、例えばポリオキシエチレンアルキルエーテル、ポリオキシエチレンアルキル（モノまたはジ）フェニルエーテル、ポリオキシエチレン（モノ、ジまたはトリ）スチリルフェニルエーテル、ポリオキシエチレンポリオキシプロピレンブロックコポリマー、ポリオキシエチレン脂肪酸（モノまたはジ）エステル、ソルビタン脂肪酸エステル、ポリオキシエチレンソルビタン脂肪酸エステル、ヒマシ油エチレンオキサイド付加物、アセチレングリコール、アセチレンアルコール、アセチレングリコールのエチレンオキサイド付加物、アセチレンアルコールのエチレンオキサイド付加物およびアルキルグリコシド等のノニオン性界面活性剤、アルキル硫酸エステル塩、アルキルベンゼンスルホン酸塩、リグニンスルホン酸塩、アルキルスルホコハク酸塩、ナフタレンスルホン酸塩、アルキルナフタレンスルホン酸塩、ナフタレンスルホン酸のホルマリン縮合物の塩、アルキルナフタレンスルホン酸のホルマリン縮合物の塩、ポリオキシエチレンアルキルエーテル硫酸または燐酸エステル塩、ポリオキシエチレン（モノまたはジ）アルキルフェニルエーテル硫酸または燐酸エステル塩、ポリオキシエチレン（モノ、ジまたはトリ）スチリルフェニルエーテル硫酸または燐酸エステル塩、ポリカルボン酸塩（例えば、ポリアクリル酸塩、ポリマレイン酸塩およびマレイン酸とオレフィンとの共重合物等）およびポリスチレンスルホン酸塩等のアニオン性界面活性剤、アルキルアミン塩およびアルキル４級アンモニウム塩等のカチオン性界面活性剤、アミノ酸型およびベタイン型等の両性界面活性剤、シリコーン系界面活性剤ならびにフッ素系界面活性剤が挙げられる。   Examples of the surfactant include polyoxyethylene alkyl ether, polyoxyethylene alkyl (mono or di) phenyl ether, polyoxyethylene (mono, di or tri) styryl phenyl ether, polyoxyethylene polyoxypropylene block copolymer, polyoxyethylene Ethylene fatty acid (mono or di) ester, sorbitan fatty acid ester, polyoxyethylene sorbitan fatty acid ester, castor oil ethylene oxide adduct, acetylene glycol, acetylene alcohol, ethylene oxide adduct of acetylene glycol, ethylene oxide adduct of acetylene alcohol and alkyl Nonionic surfactants such as glycosides, alkyl sulfate esters, alkylbenzene sulfonates, lignin sulfonates, Killsulfosuccinate, naphthalenesulfonate, alkylnaphthalenesulfonate, salt of formalin condensate of naphthalenesulfonic acid, salt of formalin condensate of alkylnaphthalenesulfonic acid, polyoxyethylene alkyl ether sulfate or phosphate ester salt, polyoxy Ethylene (mono or di) alkyl phenyl ether sulfate or phosphate ester salt, polyoxyethylene (mono, di or tri) styryl phenyl ether sulfate or phosphate ester salt, polycarboxylate (eg polyacrylate, polymaleate and Copolymers of maleic acid and olefins, etc.) and anionic surfactants such as polystyrene sulfonates, cationic surfactants such as alkylamine salts and alkyl quaternary ammonium salts, amino acid types and beties Amphoteric surfactants such as mold, and silicone-based surfactants and fluorinated surfactants.

これら界面活性剤の含有量は、特に限定されるものではないが、本発明の製剤１００重量部に対し、通常０．０５〜２０重量部の範囲が望ましい。また、これら界面活性剤は、単独で用いても２種以上を併用してもよい。   The content of these surfactants is not particularly limited, but is usually preferably in the range of 0.05 to 20 parts by weight with respect to 100 parts by weight of the preparation of the present invention. These surfactants may be used alone or in combination of two or more.

本発明化合物の施用薬量は適用場面、施用時期、施用方法、栽培作物等により差異は有るが、一般には有効成分量としてヘクタール（ha）当たり０.００５〜５０kg程度が適当である。   The application amount of the compound of the present invention varies depending on the application scene, application time, application method, cultivated crops, etc., but generally 0.005 to 50 kg per hectare (ha) is appropriate as the amount of active ingredient.

次に本発明化合物を用いる場合の製剤の配合例を示す。但し本発明の配合例は、これらのみに限定されるものではない。なお、以下の配合例において「部」は重量部を意味する。   Next, formulation examples of the preparation when the compound of the present invention is used are shown. However, the formulation examples of the present invention are not limited to these. In the following formulation examples, “parts” means parts by weight.

〔水和剤〕
本発明化合物 ０.１〜８０部
固体担体 ５〜９８.９部
界面活性剤 １〜１０部
その他 ０〜５部
その他として、例えば固結防止剤、分解防止剤等があげれらる。 [Wettable powder]
Compound of the present invention 0.1 to 80 parts Solid carrier 5 to 98.9 parts Surfactant 1 to 10 parts Others 0 to 5 parts Other examples include anti-caking agents and decomposition inhibitors.

〔乳 剤〕
本発明化合物 ０.１〜３０部
液体担体 ４５〜９５部
界面活性剤 ４.９〜１５部
その他 ０〜１０部
その他として、例えば展着剤、分解防止剤等が挙げられる。 [Milk]
Compound of the present invention 0.1 to 30 parts Liquid carrier 45 to 95 parts Surfactant 4.9 to 15 parts Others 0 to 10 parts Others include, for example, spreading agents, decomposition inhibitors and the like.

〔懸濁剤〕
本発明化合物 ０.１〜７０部
液体担体 １５〜９８.８９部
界面活性剤 １〜１２部
その他 ０.０１〜３０部
その他として、例えば凍結防止剤、増粘剤等が挙げられる。 [Suspension]
Compound of the present invention 0.1 to 70 parts Liquid carrier 15 to 98.89 parts Surfactant 1 to 12 parts Others 0.01 to 30 parts Others include, for example, antifreezing agents and thickeners.

〔顆粒水和剤〕
本発明化合物 ０.１〜９０部
固体担体 ０〜９８.９部
界面活性剤 １〜２０部
その他 ０〜１０部
その他として、例えば結合剤、分解防止剤等が挙げられる。 (Granule wettable powder)
Compound of the present invention 0.1 to 90 parts Solid carrier 0 to 98.9 parts Surfactant 1 to 20 parts Others 0 to 10 parts Others include, for example, binders and decomposition inhibitors.

〔液 剤〕
本発明化合物 ０.０１〜７０部
液体担体 ２０〜９９.９９部
その他 ０〜１０部
その他として、例えば凍結防止剤、展着剤等が挙げられる。 (Liquid)
Compound of the present invention 0.01 to 70 parts Liquid carrier 20 to 99.99 parts Others 0 to 10 parts Other examples include antifreezing agents and spreading agents.

〔粒 剤〕
本発明化合物 ０.０１〜８０部
固体担体 １０〜９９.９９部
その他 ０〜１０部
その他として、例えば結合剤、分解防止剤等が挙げられる。 [Granule]
Compound of the present invention 0.01 to 80 parts Solid carrier 10 to 99.99 parts Others 0 to 10 parts Others include, for example, binders, decomposition inhibitors and the like.

〔粉 剤〕
本発明化合物 ０.０１〜３０部
固体担体 ６５〜９９.９９部
その他 ０〜５部
その他として、例えばドリフト防止剤、分解防止剤等が挙げられる。 [Dust]
Compound of the present invention 0.01 to 30 parts Solid support 65 to 99.99 parts Others 0 to 5 parts Other examples include a drift inhibitor and a decomposition inhibitor.

次に、本発明化合物を有効成分とする製剤例をより具体的に示すが、本発明はこれらに限定されるものではない。   Next, although the formulation example which uses this invention compound as an active ingredient is shown more concretely, this invention is not limited to these.

尚、以下の配合例において、「部」は重量部を意味する。   In the following formulation examples, “parts” means parts by weight.

〔配合例１〕水和剤
本発明化合物No.１-０３８ ２０部
パイロフィライト ７４部
ソルポール５０３９ ４部
（非イオン性界面活性剤とアニオン性界面活性剤との混合物：東邦化学工業（株）商品名）
カープレックス＃８０Ｄ ２部
（合成含水珪酸：塩野義製薬（株）商品名）
以上を均一に混合粉砕して水和剤とする。 [Formulation Example 1] wettable powder Compound No. 1-038 of the present invention 20 parts Pyrophyllite 74 parts Solpol 5039 4 parts (mixture of nonionic surfactant and anionic surfactant: Toho Chemical Co., Ltd.) Product name)
Carplex # 80D 2 parts (Synthetic hydrous silicic acid: Shionogi & Co., Ltd. trade name)
The above is uniformly mixed and ground to obtain a wettable powder.

〔配合例２〕乳 剤
本発明化合物No.１-０３８ ５部
キシレン ７５部
Ｎ−メチルピロリドン １５部
ソルポール２６８０ ５部
（非イオン性界面活性剤とアニオン性界面活性剤との混合物：東邦化学工業（株）商品名）
以上を均一に混合して乳剤とする。 [Formulation Example 2] Milk Compound of the Present Invention No. 1-038 5 parts Xylene 75 parts N-methylpyrrolidone 15 parts Solpol 2680 5 parts (mixture of nonionic surfactant and anionic surfactant: Toho Chemical Industry (Product name)
The above is uniformly mixed to obtain an emulsion.

〔配合例３〕懸濁剤
本発明化合物No.１-０３８ ２５部
アグリゾールＳ−７１０ １０部
（非イオン性界面活性剤：花王（株）商品名）
ルノックス１０００Ｃ ０.５部
（アニオン性界面活性剤：東邦化学工業（株）商品名）
キサンタンガム ０.２部
水 ６４.３部
以上を均一に混合した後、湿式粉砕して懸濁剤とする。 [Composition Example 3] Suspension Agent Compound No. 1-038 of this invention 25 parts Agrisol S-710 10 parts (Nonionic surfactant: Kao Corporation trade name)
LUNOX 1000C 0.5 part (anionic surfactant: Toho Chemical Industries, Ltd. trade name)
Xanthan gum 0.2 parts water 64.3 parts After uniformly mixing the above, wet pulverize to make a suspension.

〔配合例４〕顆粒水和剤
本発明化合物No.１-０３８ ７５部
ハイテノールNE-15 ５部
（アニオン性界面活性剤：第一工業製薬（株）商品名）
バニレックスＮ １０部
（アニオン性界面活性剤：日本製紙（株）商品名）
カープレックス＃８０Ｄ １０部
（合成含水珪酸：塩野義製薬（株）商品名）
以上を均一に混合粉砕した後、少量の水を加えて攪拌混合し、押出式造粒機で造粒し、乾燥して顆粒水和剤とする。 [Composition Example 4] Granule wettable powder Compound No. 1-038 of the present invention 75 parts Hytenol NE-15 5 parts (anionic surfactant: trade name of Daiichi Kogyo Seiyaku Co., Ltd.)
Vanillex N 10 parts (anionic surfactant: Nippon Paper Industries Co., Ltd. trade name)
Carplex # 80D 10 parts (Synthetic hydrous silicic acid: Shionogi Pharmaceutical Co., Ltd. trade name)
After uniformly mixing and pulverizing the above, a small amount of water is added, stirred and mixed, granulated with an extrusion granulator, and dried to obtain a granulated wettable powder.

〔配合例５〕粒 剤
本発明化合物No.１-０３８ ５部
ベントナイト ５０部
タルク ４５部
以上を均一に混合粉砕した後、少量の水を加えて攪拌混合し、押出式造粒機で造粒し、乾燥して粒剤とする。 [Formulation Example 5] Granule Compound No. 1-038 of the present invention 5 parts Bentonite 50 parts Talc 45 parts And dried to form granules.

〔配合例６〕粉 剤
本発明化合物No.１-０３８ ３部
カープレックス＃８０Ｄ ０.５部
（合成含水珪酸：塩野義製薬（株）商品名）
カオリナイト ９５部
リン酸ジイソプロピル １.５部
以上を均一に混合粉砕して粉剤とする。 [Composition Example 6] Powder Compound of the present invention No. 1-038 3 parts Carplex # 80D 0.5 part (synthetic hydrous silicic acid: Shionogi & Co., Ltd. trade name)
Kaolinite 95 parts Diisopropyl phosphate 1.5 parts The above is uniformly mixed and ground to obtain a powder.

使用に際しては、上記製剤を水で１〜１００００倍に希釈して、又は希釈せずに直接散布する。   In use, the above preparation is diluted 1 to 10000 times with water or sprayed directly without dilution.

また、本発明化合物を農薬として使用する場合には、必要に応じて製剤時又は散布時に他種の除草剤、各種殺虫剤、殺ダニ剤、殺線虫剤、殺菌剤、植物生長調節剤、共力剤、肥料、土壌改良剤等と混合施用しても良い。   In addition, when using the compound of the present invention as an agrochemical, other types of herbicides, various insecticides, acaricides, nematicides, fungicides, plant growth regulators, as necessary, when formulated or sprayed, You may mix and apply with a synergist, a fertilizer, a soil improvement agent, etc.

特に他の農薬あるいは植物ホルモンと混合施用することにより、施用薬量の低減による低コスト化、混合薬剤の相乗作用による殺虫スペクトラムの拡大やより高い有害生物防除効果が期待できる。この際、同時に複数の公知農薬との組み合わせも可能である。本発明化合物と混合使用する農薬の種類としては、例えばファーム・ケミカルズ・ハンドブック（Farm Chemicals Handbook）１９９９年版に記載されている化合物等が挙げられる。具体的にその一般名を例示すれば次の通りであるが、必ずしもこれらのみに限定されるものではない。   In particular, when mixed with other pesticides or plant hormones, the cost can be reduced by reducing the amount of applied medicine, the insecticidal spectrum can be expanded by the synergistic action of the mixed drugs, and higher pest control effects can be expected. At this time, a combination with a plurality of known agricultural chemicals is also possible. Examples of the type of agricultural chemical used in combination with the compound of the present invention include compounds described in the Farm Chemicals Handbook 1999 edition. Specific examples of common names are as follows, but the general names are not necessarily limited to these.

殺菌剤：アシベンゾラルーＳ−メチル（acibenzolar-S-methyl）、アシルアミノベンザミド(acylaminobenzamide)、アンバム(amobam)、アムプロピルホス（ampropyfos）、アニラジン（anilazine）、アザコナゾール（azaconazole）、アゾキシストロビン（azoxystrobin）、ベナラキシル（benalaxyl）、ベノダニル（benodanil）、ベノミル（benomyl）、ベンチアゾール(benthiazole)、ベンザマクリル（benzamacril）、ビナパクリル（binapacryl）、ビフェニル（biphenyl）、ビテルタノール（bitertanol）、ベトキサジン（bethoxazine）、ボルドー液（bordeaux mixture）、ブラストサイジン−S（blasticidin-S）、ブロモコナゾール（bromoconazole）、ブピリメート（bupirimate）、ブチオベート（buthiobate）、カルシウムポリスルフィド（calcium polysulfide）、キャプタフォール（captafol）、キャプタン（captan）、カッパーオキシクロリド（copper oxychloride）、カルプロパミド（carpropamid）、カルベンダジン（carbendazim）、カルボキシン（carboxin）、ＣＧＡ−279202（試験名）、キノメチオネート（chinomethionat）、クロベンチアゾン（chlobenthiazone）、クロルフェナゾール（chlorfenazol）、クロロネブ（chloroneb）、クロロタロニル（chlorothalonil）、クロゾリネート（chlozolinate）、クフラネブ（cufraneb）、シモキサニル（cymoxanil）、シプロコナゾール（cyproconazol）、シプロジニル（cyprodinil）、シプロフラム（cyprofuram）、ダゾメット(dazomet)、デバカルブ（debacarb）、ジクロロフェン（dichlorophen）、ジクロブトラゾール（diclobutrazol）、ジクロフラニド（diclhlofluanid）、ジクロメジン（diclomedine）、ジクロラン（dicloran）、ジエトフェンカルブ（diethofencarb）、ジクロシメット（diclocymet）、ジフェノコナゾール（difenoconazole）、ジフルメトリン（diflumetorim）、ジメチリモール（dimethirimol）、ジメトモルフ（dimethomorph）、ジニコナゾール（diniconazole）、ジニコナゾール−M（diniconazole-M）、ジノカップ（dinocap）、ジフェニルアミン（diphenylamine）、ジピリチオン（dipyrithione）、ジタリムホス（ditalimfos）、ジチアノン（dithianon）、ドデモルフ（dodemorph）、ドジン（dodine）、ドラゾクソロン（drazoxolon）、エデフェノホス（edifenphos）、エポキシコナゾール（epoxiconazole）、エタコナゾール（etaconazole）、エチリモル（ethirimol）、エトリジアノール（etridiazole）、ファモキサゾン（famoxadone）、フェナリモル（fenarimol）、フェブコナゾール（febuconazole）、フェナミドン（fenamidone）、フェンダゾスラム(fendazosulam)、フェンフラム（fenfuram）、フェンヘキサミド（fenhexamid）、フェンピクロニル（fenpiclonil）、フェンプロピジン（fenpropidin）、フェンプロピモルフ（fenpropimorph）、フェンチン（fentin）、フェルバン（ferbam）、フェリムゾン（ferimzone）、フルアジナム（fluazinam）、フルジオキソニル（fludioxonil）、フルオロイミド（fluoroimide）、フルキンコナゾール（fluquinconazole）、フルシラゾール（flusilazole）、フルスルファミド（flusulfamide）、フルトラニル（flutolanil）、フルトリアフォール（flutriafol）、フォルペット（folpet）、フォセチル−アルミニウム（fosetyl-aluminium）、フベリダゾール（fuberidazole）、フララキシル（furalaxyl）、フラメトピル(furametpyr)、グアザチン（guazatine）、ヘキサクロロベンゼン（hexachlorobenzene）、ヘキサコナゾール（hexaconazole）、ヒメキサゾール（hymexazol）、イマザリル（imazalil）、イミベンコナゾール（imibenconazole）、イミノクタジン（iminoctadine）、イプコナゾール（ipconazole）、イプロベンホス（iprobenfos）、イプロジオン（iprodione）、イソプロチオラン（isoprothiolane）、イプロバリカルブ（iprovalicarb）、カスガマイシン（kasugamycin）、クレソキシム−メチル（kresoxim-methyl）、マンカッパー（mancopper）、マンコゼブ（mancozeb）、マンネブ（maneb）、メパニピリム（mepanipyrim）、メプロニル（mepronil）、メタラキシル（metalaxyl）、メトコナゾール（metconazole）、メタスルホカルブ(methasulfocarb)、メチラム（metiram）、メトミノストロビン（metominostrobin）、ミクロブタニル（myclobutanil）、ＭＴＦ−753（試験名）、ナバム（nabam）、ニッケルビス（ジメチルジチオカーバメート）（nickel bis(dimethyldithiocarbamate)）、ニトロタール−イソプロピル（nitrothal-isopropyl）、ヌアリモル（nuarimol）、ＮＮＦ−9425（試験名）、オクチリノン（octhilinone）、オフレース（ofurace）、オキサジキシル（oxadixyl）、オキシカルボキシン（oxycarboxin）、オキポコナゾールフマール酸塩（oxpoconazole fumarate）、ペフラゾエート（pefurzoate）、ペンコナゾール（penconazole）、ペンシクロン（pencycuron）、フタライド（phthalide）、ピペラリン（piperalin）、ポリオキシン（polyoxins）、炭酸水素カリウム(potassium hydrogen carbonate)、プロベナゾール（probenazole）、プロクロラズ（prochloraz）、プロシミドン（procymidone）、プロパモカルブ塩酸塩（propamocarb hydrochloride）、プロピコナゾール（propiconazole）、プロピネブ（propineb）、ピラゾホス（pyrazophos）、ピリフェノックス（pyrifenox）、ピリメタニル（pyrimethanil）、ピロキュロン（pyroquilon）、キノメチオネート(quinomethionate)、キノキシフェン（quinoxyfen）、キントゼン（quintozene）、ＲＨ7281（試験名）、炭酸水素ナトリウム(sodium hydrogen carbonate)、次亜塩素酸ナトリウム(sodium hypochlorite)、硫黄（sulfur）、スピロキサミン（spiroxamine）、テブコナゾール（tebuconazole）、テクナゼン（tecnazene）、テトラコナゾール（tetraconazole）、チアベンダゾール（thiabendazole）、チアジアジン(thiadiazin/milneb)、チフルザミド（thifluzamide）、チオファネート−メチル（thiophanate-methyl）、チラム（thiram）、トルクロホス−メチル（tolclofos-methyl）、トリルフラニド（tolylfluanid）、トリアジメホン（triadimefon）、トリアジメノール（toriadimenol）、トリアゾキシド（triazoxide）、トリシクラゾール（tricyclazole）、トリデモルフ（tridemorph）、トリフルミゾール（triflumizole）、トリホリン（triforine）、トリチコナゾール（triticonazole）、バリダマイシン（validamycin）、ビンクロゾリン（vinclozolin）、硫酸亜鉛(zinc sulfate)、ジネブ（zineb）、ジラム（ziram）及びシイタケ菌糸体抽出物など。   Bactericides: acibenzolar-S-methyl, acylaminobenzamide, amobam, ampropyfos, anilazine, azaconazole, azoxystrobin ( azoxystrobin), benalaxyl, benodanil, benomyl, benthiazole, benzamacril, binapacryl, biapacryl, biphenyl, bitertanol, beoxazine, beoxazine (Bordeaux mixture), blasticidin-S (blasticidin-S), bromoconazole, bupirimate, buthiobate, calcium polysulfide, captafol, captan ) 、 Kappa -Copper oxychloride, carpropamid, carbendazim, carboxin, CGA-279202 (test name), chinomethionat, clobenthiazone, chlorfenazol, Chloroneb, chlorothalonil, chlozolinate, cufraneb, cymoxanil, cyproconazol, cyprodinil, cyprofuram, dazomet deazot ), Dichlorophen, diclobutrazol, diclhlofluanid, diclomedine, dicloran, diethofencarb, diclocymet ), Difenoconazole, diflumetorim, dimethirimol, dimethomorph, diniconazole, dinicoazole-M, dinocap, diphenylamine, diphenylamine, dithiomine , Ditalimfos, dithianon, dodemorph, dodine, drazoxolon, edifenphos, epoxiconazole, etaconazole, ethirimol, etirimol etridiazole), famoxadone, fenarimol, febuconazole, fenamidone, fendazosulam, fenfuram, fe Hexhexamid, fenpiclonil, fenpropidin, fenpropimorph, fentin, ferbam, ferimzone, fluazinam, fludioxonil, fluoro Fluoride, fluquinconazole, flusilazole, flusulfamide, flutolanil, flutriafol, folpet, fosetyl-aluminium, fuberidazole (Fuberidazole), flaxaxyl (fururalaxyl), furametpyr, guazatine, hexachlorobenzene, hexaconazole, hymexazol, imaza Imazalil, imibenconazole, iminoctadine, ipconazole, iprobenfos, iprodione, isoprothiolane, iprovalicarb, cingamycin, kasugamycin (Kresoxim-methyl), mancopper, mancozeb, maneb, maneb, mepanipyrim, mepronil, metalaxyl, metconazole, methasulfocarb, methylasulfocarb (Metiram), metominostrobin, microbutanil, MTF-753 (test name), nabam, nickel bis (dimethyldithiocarbamate), nitroter -Isopropyl (nitrothal-isopropyl), nuarimol, NNF-9425 (test name), octhilinone, offurace, oxadixyl, oxycarboxin, oxypoconazole fumarate (Oxpoconazole fumarate), pefurzoate, penconazole, pencicuron, phthalide, piperalin, polyoxins, potassium hydrogen carbonate, probenazole, prochloraz (Prochloraz), procymidone, propamocarb hydrochloride, propiconazole, propineb, pyrazophos, pyrifenox, pyrimethanil, pyromethanil Pyroquilon, quinomethionate, quinoxyfen, quintozene, RH7281 (study name), sodium hydrogen carbonate, sodium hypochlorite, sulfur, Spiroxamine, tebuconazole, tecnazene, tetraconazole, thiabendazole, thiadiazin / milneb, thifluzamide, thiophanate-methyl, thiophanate-methyl thiram), tolclofos-methyl, tolylfluanid, triadimefon, triadimenol, triazoxide, tricyclazole, tridemorph, triflumi Triflumizole, triforine, triticonazole, validamycin, vinclozolin, zinc sulfate, zineb, ziram and shiitake mycelium extract Such.

殺バクテリア剤：ストレプトマイシン（streptomycin）、テクロフタラム(tecloftalam)、オキシテトラサイクリン（oxyterracycline）及びオキソリニックアシド（oxolinic acid）など。   Bactericides: streptomycin, tecloftalam, oxyterracycline and oxolinic acid.

殺線虫剤：アルドキシカルブ（aldoxycarb）、カズサホス（cadusafos）、フォスチアゼート（fosthiazate）、フォスチエタン（fosthietan）、オキサミル（oxamyl）及びフェナミホス（fenamiphos）など。   Nematicides: aldoxycarb, cadusafos, fosthiazate, fosthietan, oxamyl and fenamiphos.

殺ダニ剤：アセキノシル（acequinocyl）、アミトラズ（amitraz）、ビフェナゼート（bifenazate）、ブロモプロピレート（bromopropylate）、チノメチオネート（chinomethionat）、クロロベンジラート（chlorobezilate）、クロフェンテジン（clofentezine）、サイヘキサチン（cyhexatine）、ジコフォール（dicofol）、ジエノクロール（dienochlor）、エトキサゾール（etoxazole）、フェナザキン（fenazaquin）、フェンブタチンオキシド（fenbutatin oxide）、フェンプロパトリン（fenpropathrin）、フェンプロキシメート（fenproximate）、ハルフェンプロックス（halfenprox）、ヘキシチアゾックス（hexythiazox）、ミルベメクチン（milbemectin）、プロパルギット（propargite）、ピリダベン（pyridaben）、ピリミジフェン（pyrimidifen）及びテブフェンピラド（tebufenpyrad）など。   Acaricides: acequinocyl, amitraz, bifenazate, bromopropylate, chinomethionate, chlorobezilate, clofentezine, cyhexatine, Dicofol, dienochlor, etoxazole, fenazaquin, fenbutatin oxide, fenpropathrin, fenproximate, halfenprox, halfenprox, Hexythiazox, milbemectin, propargite, pyridaben, pyrimidifen and tebufenpyrad.

殺虫剤：アバメクチン（abamectin）、アセフェート（acephate）、アセタミピリド（acetamipirid）、アルディカルブ（aldicarb）、アレスリン（allethrin）、アジンホス−メチル（azinphos-methyl）、ベンジオカルブ（bendiocarb）、ベンフラカルブ（benfuracarb）、ベンスルタップ（bensultap）、ビフェントリン（bifenthrin）、ブプロフェジン（buprofezin）、ブトカルボキシン（butocarboxim）、カルバリル（carbaryl）、カルボフラン（carbofuran）、カルボスルファン（carbosulfan）、カルタップ（cartap）、クロルフェナピル（chlorfenapyr）、クロルピリホス（chlorpyrifos）、クロルフェンビンホス（chlorfenvinphos）、クロルフルアズロン（chlorfluazuron）、クロチアニジン（clothianidin）、クロマフェノジド（chromafenozide）、クロピリホス−メチル（chlorpyrifos-methyl）、シクロプロトリン（cycloprothrin）、シフルトリン（cyfluthrin）、ベータ−シフルトリン（beta-cyfluthrin）、シペルメトリン（cypermethrin）、シロマジン（cyromazine）、シハロトリン（cyhalothrin）、ラムダ−シハロトリン（lambda-cyhalothrin）、デルタメトリン（deltamethrin）、ジアフェンチウロン（diafenthiuron）、ダイアジノン（diazinon）、ジアクロデン（diacloden）、ジフルベンズロン（diflubenzuron）、ジメチルビンホス（dimethylvinphos）、ジオフェノラン（diofenolan）、ジスルフォトン（disulfoton）、ジメトエート（dimethoate）、エマメクチンベンゾエート（emamectin-benzoate）、EPN、エスフェンバレレート（esfenvalerate）、エチオフェンカルブ（ethiofencarb）、エチプロール（ethiprole）、エトフェンプロックス（etofenprox）、エトリムホス（etrimfos）、フェニトロチオン（fenitrothion）、フェノブカルブ（fenobucarb）、フェノキシカーブ（fenoxycarb）、フェンプロパトリン（fenpropathrin）、フェンバレレート（fenvalerate）、フィプロニル（fipronil）、フルアクリピリム（fluacrypyrim）、フルシトリネート（flucythrinate）、フルフェノクスウロン（flufenoxuron）、フルフェンプロックス（flufenprox）、タウ−フルバリネート（tau-fluvalinate）、ホノホス（fonophos）、フォルメタネート（formetanate）、フォルモチオン（formothion）、フラチオカルブ（furathiocarb）、ハロフェノジド（halofenozide）、ヘキサフルムロン（hexaflumuron）、ヒドラメチルノン（hydramethylnon）、イミダクロプリド（imidacloprid）、イソフェンホス（isofenphos）、インドキサカルブ（indoxacarb）、イソプロカルブ（isoprocarb）、イソキサチオン（isoxathion）、ルフェヌウロン（lufenuron）、マラチオン（malathion）、メタルデヒド（metaldehyde）、メタミドホス（methamidophos）、メチダチオン（methidathion）、メタクリホス（methacrifos）、メタルカルブ（metalcarb）、メソミル（methomyl）、メソプレン（methoprene）、メトキシクロール（methoxychlor）、メトキシフェノジド（methoxyfenozide）、モノクロトホス（monocrotophos）、ムスカルーレ（muscalure）、ニジノテフラン（nidinotefuran）、ニテンピラム（nitenpyram）、オメトエート（omethoate）、オキシデメトン−メチル（oxydemeton-methyl）、オキサミル（oxamyl）、パラチオン（parathion）、パラチオン−メチル（parathion-methyl）、ペルメトリン（permethrin）、フェントエート（phenthoate）、フォキシム（phoxim）、ホレート（phorate）、ホサロン（phosalone）、ホスメット（phosmet）、ホスファミドン（phosphamidon）、ピリミカルブ（pirimicarb）、ピリミホス−メチル（pirimiphos-methyl）、プロフェノホス（profenofos）、プロトリフェンブト（protrifenbute）、ピメトロジン（pymetrozine）、ピラクロホス（pyraclofos）、ピリプロキシフェン（pyriproxyfen）、ロテノン（rotenone）、スルプロホス（sulprofos）、シラフルオフェン（silafluofen）、スピノサド（spinosad）、スルホテップ（sulfotep）、テブフェノジド（tebfenozide）、テフルベンズロン（teflubenzuron）、テフルトリン（tefluthorin）、テルブホス（terbufos）、テトラクロロビンホス（tetrachlorvinphos）、チアクロプリド（thiacloprid）、チオシクラム（thiocyclam）、チオジカルブ（thiodicarb）、チアメトキサム（thiamethoxam）、チオファノックス（thiofanox）、チオメトン（thiometon）、トルフェンピラド（tolfenpyrad）、トラロメスリン（tralomethrin）、トリクロルホン（trichlorfon）、トリアズロン（triazuron）、トリフルムロン（triflumuron）及びバミドチオン（vamidothion）など。   Insecticides: abamectin, acephate, acetamipirid, aldicarb, allethrin, azinphos-methyl, bendiocarb, benfuracarb, benfuracarb bensultap), bifenthrin, buprofezin, butocarboxim, carbaryl, carbofuran, carbofuran, carbosulfan, cartap, chlorfenapyr, chlorpyrifos ), Chlorfenvinphos, chlorfluazuron, clothianidin, chromafenozide, chlorpyrifos-methyl, cycloprotorin ( cycloprothrin), cyfluthrin, beta-cyfluthrin, cypermethrin, cyromazine, cyhalothrin, lambda-cyhalothrin, deltamethrin, diafenthiu Ron (diafenthiuron), diazinon, diacloden, diflubenzuron, dimethylvinphos, diofenolan, disulfoton, dimethoate, emamectin-benzoate, emamectin-benzoate EPN, esfenvalerate, ethiofencarb, ethiprole, etofenprox, etrimfos, fenitrothion, fenob Carb (fenobucarb), phenoxycarb (fenoxycarb), fenpropathrin (fenpropathrin), fenvalerate, fipronil, fluacrypyrim (fluacrypyrim), flucythrinate, flufenoxuron, flufenoxuron Flufenprox, tau-fluvalinate, fonophos, formetanate, formothion, furathiocarb, halofenozide, hexaflumuron, hydra Methylnon (hydramethylnon), imidacloprid (isoidaphos), indoxacarb (indoxacarb), isoprocarb (isoprocarb), isoxathion (isoxathion), lufenuron (lufenuron), malathion (ma lathion, metalaldehyde, methamidophos, methidathion, methacrifos, metalcarb, methomyl, metoprene, methoxychlor, methoxyfenozide, monochrome Monofotophos, muscalure, nidinotefuran, nitenpyram, omethoate, oxydemeton-methyl, oxamyl, parathion, parathion-parathion -methyl), permethrin, phenthoate, phothom, phorate, phosalone, phosmet, phosphamidon, pirimicarb b), pirimiphos-methyl, profenofos, protrifenbute, pyrometrozine, pyraclofos, pyriproxyfen, rotenone, sulprofos ), Silafluofen, spinosad, sulfotep, tebfenozide, teflubenzuron, tefluthorin, terbufos, tetrachlorvinphos, iacloprid, iacloprid Thiocyclam, thiodicarb, thiamethoxam, thiofanox, thiometon, tolfenpyrad, tralomethrin, trichlorphone (Trichlorfon), triazuron, triflumuron and vamidion.

以下に本発明化合物の合成例、試験例を実施例として具体的に述べることで、本発明をさらに詳しく説明するが、本発明はこれらによって限定されるものではない。   Hereinafter, the present invention will be described in more detail by specifically describing synthesis examples and test examples of the compounds of the present invention as examples, but the present invention is not limited thereto.

［合成例］
合成例１
Ｎ1−[４−[１−ヒドロキシ−１−(５−トリフルオロメチルピリジン−２−イル)エチル]−２−メチルフェニル]−３−ヨード−Ｎ2−イソプロピルフタル酸ジアミド（本発明化合物No.2-001）。 [Synthesis example]
Synthesis example 1
N 1 - [4- [1- hydroxy-1- (5-trifluoromethyl-2-yl) ethyl] -2-methylphenyl] -3-iodo -N 2 - isopropyl phthalic acid diamide (present invention compound No .2-001).

工程１；２−シアノ−５−トリフルオロメチルピリジンの製造
２−クロロ−５−トリフルオロメチルピリジン１５.０gのＮ,Ｎ−ジメチルホルムアミド１５０ml溶液にシアン化亜鉛１９.４g及びテトラキストリフェニルホスフィンパラジウム９.６gを添加し、窒素雰囲気下、８０℃にて３時間攪拌した。反応完結後反応混合物を室温まで放冷、希アンモニア水３００mlに注ぎ、ジエチルエーテル３００mlにて抽出した。有機層を飽和食塩水２００mlにて洗浄後、無水硫酸マグネシウムで乾燥、減圧下にて溶媒を留去し、残留物を減圧蒸留（96.0〜99.0℃/40mmHg）にて精製し、目的物１０.９gを白色結晶として得た。
融点３６.０〜３８.０℃
1H NMR (CDCl3, Me4Si, 300MHz) δ9.00 (bs, 1H), 8.13 (dd, J=8.3, 2.1Hz, 1H), 7.87 (d, J=8.3Hz, 1H)。 Step 1: Preparation of 2-cyano-5-trifluoromethylpyridine 19.4 g of zinc cyanide and tetrakistriphenylphosphine palladium in a solution of 15.0 g of 2-chloro-5-trifluoromethylpyridine in 150 ml of N, N-dimethylformamide 9.6 g was added, and the mixture was stirred at 80 ° C. for 3 hours under a nitrogen atmosphere. After completion of the reaction, the reaction mixture was allowed to cool to room temperature, poured into 300 ml of dilute aqueous ammonia, and extracted with 300 ml of diethyl ether. The organic layer was washed with 200 ml of saturated brine, dried over anhydrous magnesium sulfate, the solvent was distilled off under reduced pressure, and the residue was purified by distillation under reduced pressure (96.0-99.0 ° C./40 mmHg). 9 g was obtained as white crystals.
Melting point: 36.0-38.0 ° C
1 H NMR (CDCl 3 , Me 4 Si, 300 MHz) δ 9.00 (bs, 1H), 8.13 (dd, J = 8.3, 2.1 Hz, 1H), 7.87 (d, J = 8.3 Hz, 1H).

工程２；２−アセチル−５−トリフルオロメチルピリジンの製造
窒素雰囲気下の２−シアノ−５−トリフルオロメチルピリジン４.７gのテトラヒドロフラン４０ml溶液に、−７８℃にて攪拌下、臭化メチルマグネシウムのテトラヒドロフラン溶液(０.９３Ｍ)３５.０mlを滴下し、滴下終了後室温まで昇温、室温にてさらに１時間攪拌を継続した。反応完結後、反応混合物を２Ｎ塩酸１００mlに注ぎ、酢酸エチル２００mlにて抽出した。有機層を飽和食塩水次いで無水硫酸マグネシウムの順で脱水・乾燥、減圧下にて溶媒を留去し、目的物４.５gを褐色油状物質として得た。
1H NMR (CDCl3, Me4Si, 300MHz) δ8.95 (bs, 1H), 8.16 (d, J=8.4Hz, 1H), 8.08 (dd, J=8.4, 2.1Hz, 1H), 2.76 (s, 3H)。 Step 2: Preparation of 2-acetyl-5-trifluoromethylpyridine Methylmagnesium bromide in a solution of 4.7 g of 2-cyano-5-trifluoromethylpyridine under nitrogen atmosphere in 40 ml of tetrahydrofuran at −78 ° C. with stirring 35.0 ml of a tetrahydrofuran solution (0.93M) was added dropwise, and after completion of the dropwise addition, the temperature was raised to room temperature and stirring was continued for another 1 hour at room temperature. After completion of the reaction, the reaction mixture was poured into 100 ml of 2N hydrochloric acid and extracted with 200 ml of ethyl acetate. The organic layer was dehydrated and dried in the order of saturated brine and then anhydrous magnesium sulfate, and the solvent was distilled off under reduced pressure to obtain 4.5 g of the desired product as a brown oily substance.
1 H NMR (CDCl 3 , Me 4 Si, 300 MHz) δ8.95 (bs, 1H), 8.16 (d, J = 8.4 Hz, 1H), 8.08 (dd, J = 8.4, 2.1 Hz, 1H), 2.76 ( s, 3H).

工程３；４−[１−ヒドロキシ−１−(５−トリフルオロメチルピリジン−２−イル)エチル]−２−メチルカルバニリド酸−t−ブチルの製造
窒素雰囲気下の４−ヨード−２−メチルカルバニリド酸−t−ブチル３.０gのt−ブチルメチルエーテル４０ml溶液に、−５０℃にて攪拌下、n−ブチルリチウム(１.５７Ｍヘキサン溶液)１２.５mlを滴下し、滴下終了後０℃に昇温、さらに３０分間攪拌した。次いで、この反応混合物を−７８℃に冷却、２−アセチル−５−トリフルオロメチルピリジン１.７gを添加し、徐々に０℃まで昇温、さらに同温度にて１４時間攪拌を継続した。反応完結後、反応混合物に飽和塩化アンモニウム水溶液１００mlを加え有機層を分取、水層は酢酸エチル１００mlにて抽出した。有機層を合わせ無水硫酸マグネシウムで乾燥、減圧下にて溶媒を留去した。残留物を酢酸エチル−ヘキサン（１：９〜２：３）にて溶出するシリカゲルカラムクロマトグラフィーにて精製し、目的物１.３gを褐色固体として得た。
融点１３２.０〜１３４.５℃
1H NMR (CDCl3, Me4Si, 300MHz) δ8.79 (bs, 1H), 7.86 (dd, J=8.3, 2.1Hz, 1H), 7.77 (d, J=8.3Hz, 1H), 7.42 (d, J=8.3Hz, 1H), 7.2-7.3 (m, 2H), 6.24 (bs, 1H), 5.23 (s, 1H), 2.22 (s, 3H), 1.92 (s, 3H), 1.51 (s, 9H)。 Step 3; Preparation of 4- [1-Hydroxy-1- (5-trifluoromethylpyridin-2-yl) ethyl] -2-methylcarbanilide acid-t-butyl 4-Iodo-2-under nitrogen atmosphere 12.5 ml of n-butyllithium (1.57M hexane solution) was added dropwise to a solution of 3.0 g of methylcarbanilide acid-tert-butyl in 40 ml of t-butylmethyl ether with stirring at -50 ° C. Thereafter, the temperature was raised to 0 ° C. and the mixture was further stirred for 30 minutes. Subsequently, this reaction mixture was cooled to -78 ° C, 1.7 g of 2-acetyl-5-trifluoromethylpyridine was added, the temperature was gradually raised to 0 ° C, and stirring was continued for 14 hours at the same temperature. After completion of the reaction, 100 ml of saturated aqueous ammonium chloride solution was added to the reaction mixture, the organic layer was separated, and the aqueous layer was extracted with 100 ml of ethyl acetate. The organic layers were combined and dried over anhydrous magnesium sulfate, and the solvent was distilled off under reduced pressure. The residue was purified by silica gel column chromatography eluting with ethyl acetate-hexane (1: 9-2: 3) to obtain 1.3 g of the objective product as a brown solid.
Melting point 132.0-134.5 ° C
1 H NMR (CDCl 3 , Me 4 Si, 300 MHz) δ8.79 (bs, 1H), 7.86 (dd, J = 8.3, 2.1 Hz, 1H), 7.77 (d, J = 8.3 Hz, 1H), 7.42 ( d, J = 8.3Hz, 1H), 7.2-7.3 (m, 2H), 6.24 (bs, 1H), 5.23 (s, 1H), 2.22 (s, 3H), 1.92 (s, 3H), 1.51 (s , 9H).

工程４；１−(４−アミノ−３−メチルフェニル)−１−(５−トリフルオロメチルピリジン−２−イル)エタノールの製造
４−[１−ヒドロキシ−１−(５−トリフルオロメチルピリジン−２−イル)エチル]−２−メチルカルバニリド酸−t−ブチル０.４gに、氷冷攪拌下、トリフルオロ酢酸３.０mlを滴下した。室温にて２０分攪拌を継続した後、氷冷下、飽和炭酸カリウム水溶液５０mlを加えクロロホルム３０mlにて抽出、有機層を無水硫酸ナトリウムにて乾燥後、減圧下にて溶媒を留去し、目的物０.２７gを褐色油状物質として得た。
1H NMR (CDCl3, Me4Si, 300MHz) δ8.78 (bs, 1H), 7.84 (dd, J=8.3, 2.1Hz, 1H), 7.43 (d, J=8.3Hz, 1H), 7.05-7.15 (m, 2H), 6.61 (d, J=8.3Hz, 1H), 5.15 (s, 1H), 3.59 (bs, 2H), 2.13 (s, 3H), 1.90 (s, 3H)。 Step 4; Preparation of 1- (4-amino-3-methylphenyl) -1- (5-trifluoromethylpyridin-2-yl) ethanol 4- [1-hydroxy-1- (5-trifluoromethylpyridine- To 0.4 g of 2-yl) ethyl] -2-methylcarbanilide acid-t-butyl, 3.0 ml of trifluoroacetic acid was added dropwise with stirring under ice cooling. After stirring for 20 minutes at room temperature, 50 ml of saturated aqueous potassium carbonate solution was added under ice cooling, extracted with 30 ml of chloroform, the organic layer was dried over anhydrous sodium sulfate, and the solvent was distilled off under reduced pressure. 0.27 g of product was obtained as a brown oil.
1 H NMR (CDCl 3 , Me 4 Si, 300 MHz) δ8.78 (bs, 1H), 7.84 (dd, J = 8.3, 2.1 Hz, 1H), 7.43 (d, J = 8.3 Hz, 1H), 7.05- 7.15 (m, 2H), 6.61 (d, J = 8.3Hz, 1H), 5.15 (s, 1H), 3.59 (bs, 2H), 2.13 (s, 3H), 1.90 (s, 3H).

工程５；Ｎ1−[４−[１−ヒドロキシ−１−(４−トリフルオロメチルピリジン−２−イル)エチル]−２−メチルフェニル]−３−ヨード−Ｎ2−イソプロピルフタル酸ジアミドの製造
３−ヨード−Ｎ−イソプロピルフタルアミド酸０.３６gのトルエン５ml溶液に、室温にて攪拌下、トリフルオロ酢酸無水物０.２６gを滴下した。同温度にて２時間攪拌した後、減圧下に溶媒を留去、残留物をアセトニトリル３.０mlに溶解し、１−(４−アミノ−３−メチルフェニル)−１−(５−トリフルオロメチルピリジン−２−イル)エタノール０.２７gを添加、室温にて２時間攪拌を継続した。反応完結後、減圧下にて溶媒を留去、残留物を酢酸エチル−ヘキサン（３：２）にて溶出するシリカゲルカラムクロマトグラフィーにて精製し、目的物０.４３gを褐色油状物質として得た。
1H NMR (CDCl3, Me4Si, 300MHz) δ8.80 (bs, 1H), 8.29 (bs, 1H), 7.7-8.05 (m, 4H), 7.1-7.5 (m, 4H), 5.84 (d, J=8.3Hz, 1H), 5.28 (s, 1H), 4.1-4.3 (m, 1H), 2.28 (s, 3H), 1.94 (s, 3H), 1.17 (d, J=6.6Hz, 6H)。 Step 5; N 1 - preparation of isopropyl phthalic diamides - [4- [1-hydroxy-1- (4-trifluoromethyl-2-yl) ethyl] -2-methylphenyl] -3-iodo--N 2 To a solution of 0.36 g of 3-iodo-N-isopropylphthalamic acid in 5 ml of toluene was added dropwise 0.26 g of trifluoroacetic anhydride at room temperature with stirring. After stirring at the same temperature for 2 hours, the solvent was distilled off under reduced pressure, the residue was dissolved in 3.0 ml of acetonitrile, and 1- (4-amino-3-methylphenyl) -1- (5-trifluoromethyl) was dissolved. 0.27 g of pyridin-2-yl) ethanol was added and stirring was continued at room temperature for 2 hours. After completion of the reaction, the solvent was distilled off under reduced pressure, and the residue was purified by silica gel column chromatography eluting with ethyl acetate-hexane (3: 2) to obtain 0.43 g of the desired product as a brown oily substance. .
1 H NMR (CDCl 3 , Me 4 Si, 300 MHz) δ8.80 (bs, 1H), 8.29 (bs, 1H), 7.7-8.05 (m, 4H), 7.1-7.5 (m, 4H), 5.84 (d , J = 8.3Hz, 1H), 5.28 (s, 1H), 4.1-4.3 (m, 1H), 2.28 (s, 3H), 1.94 (s, 3H), 1.17 (d, J = 6.6Hz, 6H) .

合成例２
Ｎ1−[４−[１−(４−ブロモジフルオロメトキシフェニル)−２,２,２−トリフルオロ−１−ヒドロキシエチル]−２−メチルフェニル]−３−ヨード−Ｎ2−イソプロピルフタル酸ジアミド（本発明化合物No.1-010）。 Synthesis example 2
N 1 - [4- [1- ( 4- bromo-difluoromethoxyphenyl) -2,2,2-trifluoro-1-hydroxyethyl] -2-methylphenyl] -3-iodo -N 2 - isopropyl phthalic acid diamide (Invention compound No. 1-010).

工程１；４'−ブロモジフルオロメトキシ−２,２,２−トリフルオロアセトフェノンの製造
２,２,２−トリフルオロ−４'−ヒドロキシアセトフェノン２.０gの１,３−ジメチル−２−イミダゾリジノン１０ml溶液に、氷冷攪拌下、５５％油性水素化ナトリウム０.５１gを添加し、室温にて３０分間攪拌した。次いでこの反応混合物を、氷冷攪拌下、ジブロモジフルオロメタン１１.０gの１,３−ジメチル−２−イミダゾリジノン１０ml溶液に内温１０℃以下を保つ速度で滴下し、滴下終了後室温まで昇温、カリウム−t−ブトキシド０.１２gを添加した後、同温度にてさらに１時間攪拌を継続した。反応完結後、反応混合物を氷水１５０mlに注ぎジエチルエーテル１００mlにて抽出、有機層を水洗後、無水硫酸マグネシウムで乾燥、減圧下にて溶媒を留去した。残留物を酢酸エチル−ヘキサン（１：１９〜１：９）にて溶出するシリカゲルカラムクロマトグラフィーにて精製し、目的物１.８３gを黄色油状物質として得た。
1H NMR (CDCl3, Me4Si, 300MHz) δ8.16 (d, J=8.8Hz, 2H), 7.43 (d, J=8.8Hz, 2H)。 Step 1: Preparation of 4'-bromodifluoromethoxy-2,2,2-trifluoroacetophenone 2,2,2-trifluoro-4'-hydroxyacetophenone 2.0 g of 1,3-dimethyl-2-imidazolidinone To a 10 ml solution, 0.51 g of 55% oily sodium hydride was added under ice-cooling and stirred at room temperature for 30 minutes. The reaction mixture was then added dropwise to a solution of 11.0 g of dibromodifluoromethane in 10 ml of 1,3-dimethyl-2-imidazolidinone at a rate maintaining the internal temperature of 10 ° C. or lower while stirring with ice cooling. After adding 0.12 g of warm potassium-t-butoxide, stirring was continued for another hour at the same temperature. After completion of the reaction, the reaction mixture was poured into 150 ml of ice water and extracted with 100 ml of diethyl ether. The organic layer was washed with water, dried over anhydrous magnesium sulfate, and the solvent was distilled off under reduced pressure. The residue was purified by silica gel column chromatography eluting with ethyl acetate-hexane (1: 19-1: 9) to give 1.83 g of the desired product as a yellow oil.
1 H NMR (CDCl 3 , Me 4 Si, 300 MHz) δ8.16 (d, J = 8.8 Hz, 2H), 7.43 (d, J = 8.8 Hz, 2H).

工程２；４−[１−(４−ブロモジフルオロメトキシフェニル)−２,２,２−トリフルオロ−１−ヒドロキシエチル]−２−メチルカルバニリド酸−t−ブチルの製造
窒素雰囲気下の４−ヨード−２−メチルカルバニリド酸−t−ブチル１.９１gのt−ブチルメチルエーテル２５ml溶液に、−６０℃にて攪拌下、n−ブチルリチウム(１.５８Ｍヘキサン溶液)８.０mlを滴下し、滴下終了後０℃に昇温、さらに３０分間攪拌した。次いで、この反応混合物を−７８℃に冷却、４'−ブロモジフルオロメトキ−２,２,２−トリフルオロアセトフェノン７.０gを添加し、徐々に０℃まで昇温、さらに同温度にて３０分間攪拌を継続した。反応完結後、反応混合物を飽和塩化アンモニウム水溶液１００mlに注ぎ有機層を分取、水層は酢酸エチル５０mlにて抽出した。有機層を合わせ無水硫酸マグネシウムで乾燥、減圧下にて溶媒を留去した。残留物を酢酸エチル−ヘキサン（１：１９〜１：４）にて溶出するシリカゲルカラムクロマトグラフィーにて精製し、目的物１.０gを褐色油状物質として得た。
1H NMR (CDCl3, Me4Si, 300MHz) δ7.87 (d, J=8.3Hz, 1H), 7.51 (d, J=8.8Hz, 2H), 7.15-7.35 (m, 4H), 6.32 (bs, 1H), 3.00 (bs, 1H), 2.24 (s, 3H), 1.52 (s, 9H)。 Step 2; Preparation of 4- [1- (4-Bromodifluoromethoxyphenyl) -2,2,2-trifluoro-1-hydroxyethyl] -2-methylcarbanilide acid-t-butyl 4 under nitrogen atmosphere -Iodo-2-methylcarbanilic acid-t-butyl In a solution of 1.91 g of t-butyl methyl ether in 25 ml, with stirring at -60 ° C, 8.0 ml of n-butyl lithium (1.58 M hexane solution) was added. After the dropwise addition, the temperature was raised to 0 ° C. after completion of the dropwise addition, and the mixture was further stirred for 30 minutes. The reaction mixture was then cooled to -78 ° C, 7.0 g of 4'-bromodifluoromethoxy-2,2,2-trifluoroacetophenone was added, the temperature was gradually raised to 0 ° C, and further 30 minutes at the same temperature. Stirring was continued. After completion of the reaction, the reaction mixture was poured into 100 ml of saturated aqueous ammonium chloride solution, the organic layer was separated, and the aqueous layer was extracted with 50 ml of ethyl acetate. The organic layers were combined and dried over anhydrous magnesium sulfate, and the solvent was distilled off under reduced pressure. The residue was purified by silica gel column chromatography eluting with ethyl acetate-hexane (1: 19-1: 4) to obtain 1.0 g of the objective product as a brown oily substance.
1 H NMR (CDCl 3 , Me 4 Si, 300MHz) δ7.87 (d, J = 8.3Hz, 1H), 7.51 (d, J = 8.8Hz, 2H), 7.15-7.35 (m, 4H), 6.32 ( bs, 1H), 3.00 (bs, 1H), 2.24 (s, 3H), 1.52 (s, 9H).

工程３；１−(４−アミノ−３−メチルフェニル)−１−(４−ブロモジフルオロメトキシフェニル)−２,２,２−トリフルオロエタノールの製造
４−[１−(４−ブロモジフルオロメトキシフェニル)−２,２,２−トリフルオロ−１−ヒドロキシエチル]−２−メチルカルバニリド酸−t−ブチル１.０gに、氷冷攪拌下、トリフルオロ酢酸３.０mlを滴下した。室温にて２０分攪拌を継続した後、氷冷下、飽和炭酸カリウム水溶液５０mlを加えクロロホルム５０mlにて抽出、有機層を無水硫酸ナトリウムにて乾燥後、減圧下にて溶媒を留去し、目的物０.６gを褐色結晶として得た。
融点７７.５〜８０.５℃
1H NMR (CDCl3, Me4Si, 300MHz) δ7.53 (d, J=8.5Hz, 2H), 7.0-7.25 (m, 4H), 6.61 (d, J=8.0Hz, 1H), 2.65-3.15 (bs, 3H), 2.13 (s, 3H)。 Step 3; Preparation of 1- (4-amino-3-methylphenyl) -1- (4-bromodifluoromethoxyphenyl) -2,2,2-trifluoroethanol 4- [1- (4-Bromodifluoromethoxyphenyl) ) -2,2,2-trifluoro-1-hydroxyethyl] -2-methylcarbanilide acid-t-butyl (1.0 g) was dropwise added with trifluoroacetic acid (3.0 ml) with stirring under ice-cooling. After stirring for 20 minutes at room temperature, 50 ml of saturated aqueous potassium carbonate solution was added under ice cooling, extracted with 50 ml of chloroform, the organic layer was dried over anhydrous sodium sulfate, and the solvent was distilled off under reduced pressure. 0.6 g of the product was obtained as brown crystals.
Melting point: 77.5-80.5 ° C
1 H NMR (CDCl 3 , Me 4 Si, 300MHz) δ7.53 (d, J = 8.5Hz, 2H), 7.0-7.25 (m, 4H), 6.61 (d, J = 8.0Hz, 1H), 2.65- 3.15 (bs, 3H), 2.13 (s, 3H).

工程４；Ｎ1−[４−[１−(４−ブロモジフルオロメトキシフェニル)−２,２,２−トリフルオロ−１−ヒドロキシエチル]−２−メチルフェニル]−３−ヨード−Ｎ2−イソプロピルフタル酸ジアミドの製造
３−ヨード−Ｎ−イソプロピルフタルアミド酸０.２５gのトルエン５ml溶液に、室温にて攪拌下、トリフルオロ酢酸無水物０.１８gを滴下した。同温度にて１時間攪拌した後、減圧下に溶媒を留去、残留物をアセトニトリル３mlに溶解し、１−(４−アミノ−３−メチルフェニル)−１−(４−ブロモジフルオロメトキシフェニル)−２,２,２−トリフルオロエタノール０.２７gを添加、室温にて１５時間攪拌を継続した。反応完結後、減圧下にて溶媒を留去、残留物を酢酸エチル−ヘキサン（２：３）にて溶出するシリカゲルカラムクロマトグラフィーにて精製し、目的物０.１３gを褐色結晶として得た。
融点９７.０〜１０２.５℃
1H NMR (CDCl3, Me4Si, 300MHz) δ8.39 (bs, 1H), 8.06 (d, J=8.8Hz, 1H), 7.96 (d, J=7.8Hz, 1H), 7.78 (d, J=8.0Hz, 1H), 7.53 (d, J=8.8Hz, 2H), 7.1-7.35 (m, 5H), 5.86 (d, J=8.0Hz, 1H), 4.15-4.3 (m, 1H), 3.16 (s, 1H), 2.30 (s, 3H), 1.17 (d, J=6.6Hz, 6H)。 Step 4; N 1 - [4- [ 1- (4- bromo-difluoromethoxyphenyl) -2,2,2-trifluoro-1-hydroxyethyl] -2-methylphenyl] -3-iodo -N 2 - isopropyl Preparation of phthalic acid diamide 0.18 g of trifluoroacetic anhydride was added dropwise to a solution of 0.25 g of 3-iodo-N-isopropylphthalamic acid in 5 ml of toluene with stirring at room temperature. After stirring at the same temperature for 1 hour, the solvent was distilled off under reduced pressure, and the residue was dissolved in 3 ml of acetonitrile to give 1- (4-amino-3-methylphenyl) -1- (4-bromodifluoromethoxyphenyl). -2,2,2-trifluoroethanol (0.27 g) was added, and stirring was continued at room temperature for 15 hours. After completion of the reaction, the solvent was distilled off under reduced pressure, and the residue was purified by silica gel column chromatography eluting with ethyl acetate-hexane (2: 3) to obtain 0.13 g of the desired product as brown crystals.
Melting point 97.0-102.5 ° C
1 H NMR (CDCl 3 , Me 4 Si, 300 MHz) δ 8.39 (bs, 1H), 8.06 (d, J = 8.8Hz, 1H), 7.96 (d, J = 7.8Hz, 1H), 7.78 (d, J = 8.0Hz, 1H), 7.53 (d, J = 8.8Hz, 2H), 7.1-7.35 (m, 5H), 5.86 (d, J = 8.0Hz, 1H), 4.15-4.3 (m, 1H), 3.16 (s, 1H), 2.30 (s, 3H), 1.17 (d, J = 6.6Hz, 6H).

合成例３
Ｎ1−[４−[２,２,２−トリフルオロ−１−ヒドロキシ−１−(４−トリフルオロメトキシフェニル)エチル]−２−メチルフェニル]−３−ヨード−Ｎ2−イソプロピルフタル酸ジアミド（本発明化合物No.1-009）。 Synthesis example 3
N 1 - [4- [2,2,2- trifluoro-1-hydroxy-1- (4-trifluoromethoxyphenyl) ethyl] -2-methylphenyl] -3-iodo -N 2 - isopropyl phthalic acid diamide (Invention compound No. 1-009).

工程１；[２,２,２−トリフルオロ−１−メトキシ−１−(４−トリフルオロメトキシフェニル)エチル]トリメチルシランの製造
４−トリフルオロメトキシ安息香酸メチル１０.０gの１,２−ジメトキシエタン５５ml溶液に、氷冷攪拌下、(トリフルオロメチル)トリメチルシラン１３.６g及びフッ化セシウム０.１gを添加し、攪拌下、２時間かけて室温まで昇温した。室温にてさらに１時間攪拌を継続した後、反応混合物を氷水２００mlに注ぎ酢酸エチル２００mlにて抽出、有機層を無水硫酸マグネシウムで乾燥後、減圧下にて溶媒を留去した。残留物をヘキサンにて溶出するシリカゲルカラムクロマトグラフィーにて精製し、目的物１６.０gを無色油状物質として得た。
1H NMR (CDCl3, Me4Si, 300MHz) δ7.62 (d, J=8.5Hz, 2H), 7.23 (d, J=8.5Hz, 2H), 3.21 (s, 3H), 0.27 (s, 9H)。 Step 1: Preparation of [2,2,2-trifluoro-1-methoxy-1- (4-trifluoromethoxyphenyl) ethyl] trimethylsilane 10.0 g of 1,4-dimethoxymethyl 4-trifluoromethoxybenzoate To a 55 ml solution of ethane, 13.6 g of (trifluoromethyl) trimethylsilane and 0.1 g of cesium fluoride were added with stirring under ice cooling, and the temperature was raised to room temperature over 2 hours with stirring. After further stirring for 1 hour at room temperature, the reaction mixture was poured into 200 ml of ice water, extracted with 200 ml of ethyl acetate, the organic layer was dried over anhydrous magnesium sulfate, and the solvent was distilled off under reduced pressure. The residue was purified by silica gel column chromatography eluting with hexane to obtain 16.0 g of the desired product as a colorless oil.
1 H NMR (CDCl 3 , Me 4 Si, 300 MHz) δ7.62 (d, J = 8.5Hz, 2H), 7.23 (d, J = 8.5Hz, 2H), 3.21 (s, 3H), 0.27 (s, 9H).

工程２；２,２,２−トリフルオロ−４'−トリフルオロメトキシアセトフェノンの製造
[２,２,２−トリフルオロ−１−メトキシ−１−(４−トリフルオロメトキシフェニル)エチル]トリメチルシラン１６.０gのテトラヒドロフラン５５ml溶液に、室温にて攪拌下、フッ化テトラブチルアンモニウムのテトラヒドロフラン１Ｍ溶液９.５mlを添加し、室温にて２０分間攪拌した。反応完結後、反応混合物に飽和炭酸水素ナトリウム水溶液２００mlを加え酢酸エチル２００mlにて抽出、有機層を無水硫酸マグネシウムで乾燥後、減圧下にて溶媒を留去し、目的物１０.８gを褐色油状物質として得た。
1H NMR (CDCl3, Me4Si, 300MHz) δ8.15 (d, J=8.8Hz, 2H), 7.37 (d, J=8.8Hz, 2H)。 Step 2: Production of 2,2,2-trifluoro-4′-trifluoromethoxyacetophenone
[2,2,2-trifluoro-1-methoxy-1- (4-trifluoromethoxyphenyl) ethyl] trimethylsilane (16.0 g) in tetrahydrofuran (55 ml) was stirred at room temperature with tetrahydrofuran of tetrabutylammonium fluoride. 9.5 ml of 1M solution was added and stirred at room temperature for 20 minutes. After completion of the reaction, 200 ml of saturated aqueous sodium hydrogen carbonate solution was added to the reaction mixture, extracted with 200 ml of ethyl acetate, the organic layer was dried over anhydrous magnesium sulfate, the solvent was distilled off under reduced pressure, and 10.8 g of the desired product was obtained as a brown oil. Obtained as material.
1 H NMR (CDCl 3 , Me 4 Si, 300 MHz) δ8.15 (d, J = 8.8 Hz, 2H), 7.37 (d, J = 8.8 Hz, 2H).

工程３；４−[２,２,２−トリフルオロ−１−ヒドロキシ−１−(４−トリフルオロメトキシフェニル)エチル]−２−メチルカルバニリド酸−t−ブチルの製造
窒素雰囲気下の４−ヨード−２−メチルカルバニリド酸−t−ブチル１０.０gのt−ブチルメチルエーテル１３０ml溶液に、−６０℃にて攪拌下、n−ブチルリチウム(１.５８Ｍヘキサン溶液)４１.８mlを滴下し、滴下終了後０℃に昇温、さらに３０分間攪拌した。次いで、この反応混合物を−７８℃に冷却、２,２,２−トリフルオロ−４'−トリフルオロメトキシアセトフェノン７.７５gを添加し、徐々に０℃まで昇温、さらに同温度にて３０分間攪拌を継続した。反応完結後、反応混合物を飽和塩化アンモニウム水溶液３００mlに注ぎ有機層を分取、水層は酢酸エチル１００mlにて抽出した。有機層を合わせ無水硫酸マグネシウムで乾燥、減圧下にて溶媒を留去した。残留物を酢酸エチル−ヘキサン（１：１９〜１：４）にて溶出するシリカゲルカラムクロマトグラフィーにて精製し、目的物９.０gを無色油状物質として得た。
1H NMR (CDCl3, Me4Si, 300MHz) δ7.87 (d, J=8.5Hz, 1H), 7.50 (d, J=8.8Hz, 2H), 7.1-7.35 (m, 4H), 6.31 (bs, 1H), 2.95 (bs, 1H), 2.23 (s, 3H), 1.52 (s, 9H)。 Step 3; Preparation of 4- [2,2,2-trifluoro-1-hydroxy-1- (4-trifluoromethoxyphenyl) ethyl] -2-methylcarbanilide acid-t-butyl 4 under nitrogen atmosphere -Iodo-2-methylcarbanilic acid-t-butyl 10.0 g of t-butyl methyl ether in 130 ml was stirred at -60 ° C and 41.8 ml of n-butyl lithium (1.58 M hexane solution) was added. After the dropwise addition, the temperature was raised to 0 ° C. after completion of the dropwise addition, and the mixture was further stirred for 30 minutes. The reaction mixture was then cooled to −78 ° C., and 2,2,2-trifluoro-4′-trifluoromethoxyacetophenone (7.75 g) was added, the temperature was gradually raised to 0 ° C., and the temperature was further increased for 30 minutes. Stirring was continued. After completion of the reaction, the reaction mixture was poured into 300 ml of saturated aqueous ammonium chloride solution, the organic layer was separated, and the aqueous layer was extracted with 100 ml of ethyl acetate. The organic layers were combined and dried over anhydrous magnesium sulfate, and the solvent was distilled off under reduced pressure. The residue was purified by silica gel column chromatography eluting with ethyl acetate-hexane (1: 19-1: 4) to obtain 9.0 g of the objective product as a colorless oil.
1 H NMR (CDCl 3 , Me 4 Si, 300 MHz) δ7.87 (d, J = 8.5Hz, 1H), 7.50 (d, J = 8.8Hz, 2H), 7.1-7.35 (m, 4H), 6.31 ( bs, 1H), 2.95 (bs, 1H), 2.23 (s, 3H), 1.52 (s, 9H).

工程４；１−(４−アミノ−３−メチルフェニル)−２,２,２−トリフルオロ−１−(４−トリフルオロメトキシフェニル)エタノールの製造
４−[２,２,２−トリフルオロ−１−ヒドロキシ−１−(４−トリフルオロメトキシフェニル)エチル]−２−メチルカルバニリド酸−t−ブチル９.０gに、氷冷攪拌下、トリフルオロ酢酸１６.０mlを滴下した。室温にて３０分攪拌を継続した後、氷冷下、飽和炭酸カリウム水溶液２００mlを加えクロロホルム１００ml及び酢酸エチル１００mlにて抽出、有機層を併せて無水硫酸ナトリウムにて乾燥後、減圧下にて溶媒を留去し、目的物６.８gを黄色結晶として得た。
融点１２７.０〜１２８.５℃
1H NMR (CDCl3, Me4Si, 300MHz) δ7.51 (d, J=8.5Hz, 2H), 7.0-7.25 (m, 4H), 6.60 (d, J=8.3Hz, 1H), 3.06 (bs, 3H), 2.13 (s, 3H)。 Step 4: Production of 1- (4-amino-3-methylphenyl) -2,2,2-trifluoro-1- (4-trifluoromethoxyphenyl) ethanol 4- [2,2,2-trifluoro- 19.0 ml of trifluoroacetic acid was added dropwise to 9.0 g of 1-hydroxy-1- (4-trifluoromethoxyphenyl) ethyl] -2-methylcarbanilide acid-t-butyl under ice-cooling and stirring. After stirring for 30 minutes at room temperature, 200 ml of saturated aqueous potassium carbonate solution was added under ice cooling, extracted with 100 ml of chloroform and 100 ml of ethyl acetate, the organic layers were combined and dried over anhydrous sodium sulfate, and then the solvent was removed under reduced pressure. Was distilled off to obtain 6.8 g of the desired product as yellow crystals.
Melting point 127.0-128.5 ° C
1 H NMR (CDCl 3 , Me 4 Si, 300MHz) δ7.51 (d, J = 8.5Hz, 2H), 7.0-7.25 (m, 4H), 6.60 (d, J = 8.3Hz, 1H), 3.06 ( bs, 3H), 2.13 (s, 3H).

工程５；Ｎ1−[４−[２,２,２−トリフルオロ−１−ヒドロキシ−１−(４−トリフルオロメトキシフェニル)エチル]−２−メチルフェニル]−３−ヨード−Ｎ2−イソプロピルフタル酸ジアミドの製造
３−ヨード−Ｎ−イソプロピルフタルアミド酸０.２gのトルエン５ml溶液に、室温にて攪拌下、トリフルオロ酢酸無水物１.０gを滴下した。同温度にて３０分間攪拌した後、減圧下に溶媒を留去、残留物をアセトニトリル５mlに溶解し、１−(４−アミノ−３−メチルフェニル)−２,２,２−トリフルオロ−１−(４−トリフルオロメトキシフェニル)エタノール０.２g及びトリフルオロ酢酸１滴を添加、室温にて４時間攪拌を継続した。反応完結後、減圧下にて溶媒を留去、残留物を酢酸エチル−ヘキサン（１：１）にて溶出するシリカゲルカラムクロマトグラフィーにて精製し、目的物０.３３gを無色樹脂状物質として得た。
1H NMR (CDCl3, Me4Si, 400MHz) δ8.39 (bs, 1H), 8.10 (d, J=8.8Hz, 1H), 7.95 (d, J=7.6Hz, 1H), 7.80 (d, J=8.0Hz, 1H), 7.52 (d, J=8.0Hz, 2H), 7.2-7.35 (m, 5H), 5.90 (d, J=8.0Hz, 1H), 4.15-4.3 (m, 1H), 3.01 (s, 1H), 2.33 (s, 3H), 1.17 (d, J=6.6Hz, 6H)。 Step 5; N 1- [4- [2,2,2-trifluoro-1-hydroxy-1- (4-trifluoromethoxyphenyl) ethyl] -2-methylphenyl] -3-iodo-N 2 -isopropyl Preparation of phthalic acid diamide 1.0 g of trifluoroacetic anhydride was added dropwise to a solution of 0.2 g of 3-iodo-N-isopropylphthalamic acid in 5 ml of toluene with stirring at room temperature. After stirring at the same temperature for 30 minutes, the solvent was distilled off under reduced pressure, the residue was dissolved in 5 ml of acetonitrile, and 1- (4-amino-3-methylphenyl) -2,2,2-trifluoro-1 -0.2 g of (4-trifluoromethoxyphenyl) ethanol and 1 drop of trifluoroacetic acid were added and stirring was continued for 4 hours at room temperature. After completion of the reaction, the solvent was distilled off under reduced pressure, and the residue was purified by silica gel column chromatography eluting with ethyl acetate-hexane (1: 1) to obtain 0.33 g of the objective product as a colorless resinous substance. It was.
1 H NMR (CDCl 3 , Me 4 Si, 400 MHz) δ 8.39 (bs, 1H), 8.10 (d, J = 8.8Hz, 1H), 7.95 (d, J = 7.6Hz, 1H), 7.80 (d, J = 8.0Hz, 1H), 7.52 (d, J = 8.0Hz, 2H), 7.2-7.35 (m, 5H), 5.90 (d, J = 8.0Hz, 1H), 4.15-4.3 (m, 1H), 3.01 (s, 1H), 2.33 (s, 3H), 1.17 (d, J = 6.6Hz, 6H).

合成例４
Ｎ1−[４−[２,２,２−トリフルオロ−１−ヒドロキシ−１−(２,２,３,３−テトラフルオロ−１,４−ジオキサ−２,３−ジヒドロナフタレン−６−イル)エチル]−２−メチルフェニル]−３−ヨード−Ｎ2−イソプロピルフタル酸ジアミド（本発明化合物No.1-028）。 Synthesis example 4
N 1- [4- [2,2,2-trifluoro-1-hydroxy-1- (2,2,3,3-tetrafluoro-1,4-dioxa-2,3-dihydronaphthalen-6-yl ) Ethyl] -2-methylphenyl] -3-iodo-N 2 -isopropylphthalic acid diamide (Compound No. 1-028 of the present invention).

工程１；２−メチル−４−トリフルオロアセチルカルバニリド酸−t−ブチルの製造
窒素雰囲気下の４−ヨード−２−メチルカルバニリド酸−t−ブチル１０.０gのジエチルエーテル３００ml溶液に、−１０℃にて攪拌下、n−ブチルリチウム(１.５Ｍヘキサン溶液)４５.０mlを滴下し、滴下終了後、同温度にて３０分間攪拌した。次いで、この反応混合物を−７８℃に冷却、トリフルオロ酢酸エチル９.５gを滴下し、滴下終了後、同温度にてさらに１時間攪拌を継続した。反応完結後、反応混合物を−１０℃まで昇温、２Ｎ塩酸１００mlを加えて激しく攪拌した後、有機層を分取、飽和食塩水次いで無水硫酸マグネシウムの順で脱水・乾燥、減圧下にて溶媒を留去した。残留物をジエチルエーテル−ヘキサン（１：４）にて溶出するシリカゲルカラムクロマトグラフィーにて精製し、目的物３.２gを白色結晶として得た。
融点８５.０〜８７.０℃
1H NMR (CDCl3, Me4Si, 300MHz) δ8.25 (d, J=8.8Hz, 1H), 7.8-8.0 (m, 2H), 6.62 (bs, 1H), 2.32 (s, 3H), 1.55 (s, 9H)。 Step 1: Preparation of 2-methyl-4-trifluoroacetylcarbanilic acid-t-butyl In a nitrogen atmosphere, a solution of 10.0 g of 4-iodo-2-methylcarbanilide-t-butyl in 300 ml of diethyl ether was added. While stirring at −10 ° C., 45.0 ml of n-butyllithium (1.5M hexane solution) was added dropwise. After completion of the dropwise addition, the mixture was stirred at the same temperature for 30 minutes. Next, this reaction mixture was cooled to -78 ° C, and 9.5 g of ethyl trifluoroacetate was added dropwise. After completion of the dropwise addition, stirring was continued for another 1 hour at the same temperature. After completion of the reaction, the reaction mixture was heated to −10 ° C. and 100 ml of 2N hydrochloric acid was added and stirred vigorously. Was distilled off. The residue was purified by silica gel column chromatography eluting with diethyl ether-hexane (1: 4) to obtain 3.2 g of the objective product as white crystals.
Melting point: 85.0-87.0 ° C
1 H NMR (CDCl 3 , Me 4 Si, 300 MHz) δ8.25 (d, J = 8.8Hz, 1H), 7.8-8.0 (m, 2H), 6.62 (bs, 1H), 2.32 (s, 3H), 1.55 (s, 9H).

工程２；４−[２,２,２−トリフルオロ−１−ヒドロキシ−１−(２,２,３,３−テトラフルオロ−１,４−ジオキサ−２,３−ジヒドロナフタレン−６−イル)エチル]−２−メチルカルバニリド酸−t−ブチルの製造
窒素雰囲気下の６−ブロモ−２,２,３,３−テトラフルオロ−１,４−ジオキサ−２,３−ジヒドロナフタレン２.３７gのt−ブチルメチルエーテル３０ml溶液に、−４０℃にて攪拌下、n−ブチルリチウム(１.５８Ｍヘキサン溶液)５.４mlを滴下し、滴下終了後０℃に昇温、さらに１時間攪拌した。次いで、この反応混合物を−５０℃に冷却、２−メチル−４−トリフルオロアセチルカルバニリド酸−t−ブチル１.０gのt−ブチルメチルエーテル２０ml溶液を滴下し、徐々に０℃まで昇温、さらに同温度にて１時間攪拌を継続した。反応完結後、反応混合物を飽和塩化アンモニウム水溶液１００mlに注ぎ有機層を分取、水層は酢酸エチル５０mlにて抽出した。有機層を併せて飽和食塩水次いで無水硫酸マグネシウムの順で脱水・乾燥、減圧下にて溶媒を留去した。残留物を酢酸エチル−ヘキサン（１：４）にて溶出するシリカゲルカラムクロマトグラフィーにて精製し、目的物２.３gを黄色油状物質として得た。 Step 2; 4- [2,2,2-trifluoro-1-hydroxy-1- (2,2,3,3-tetrafluoro-1,4-dioxa-2,3-dihydronaphthalen-6-yl) Preparation of ethyl] -2-methylcarbanilide-t-butyl 2.37 g of 6-bromo-2,2,3,3-tetrafluoro-1,4-dioxa-2,3-dihydronaphthalene under nitrogen atmosphere 5.4 ml of n-butyllithium (1.58 M hexane solution) was added dropwise to a 30 ml solution of t-butyl methyl ether with stirring at -40 ° C. After completion of the dropwise addition, the temperature was raised to 0 ° C and further stirred for 1 hour. . The reaction mixture was then cooled to −50 ° C., and a solution of 1.0 g of 2-methyl-4-trifluoroacetylcarbanilic acid-tert-butyl in 20 ml of t-butyl methyl ether was added dropwise and gradually raised to 0 ° C. Stirring was continued for 1 hour at the same temperature. After completion of the reaction, the reaction mixture was poured into 100 ml of saturated aqueous ammonium chloride solution, the organic layer was separated, and the aqueous layer was extracted with 50 ml of ethyl acetate. The organic layers were combined, dehydrated and dried in the order of saturated brine and then anhydrous magnesium sulfate, and the solvent was distilled off under reduced pressure. The residue was purified by silica gel column chromatography eluting with ethyl acetate-hexane (1: 4) to obtain 2.3 g of the objective product as a yellow oil.

工程３；１−(４−アミノ−３−メチルフェニル)−２,２,２−トリフルオロ−１−(２,２,３,３−テトラフルオロ−１,４−ジオキサ−２,３−ジヒドロナフタレン−６−イル)エタノールの製造
４−[２,２,２−トリフルオロ−１−ヒドロキシ−１−(２,２,３,３−テトラフルオロ−１,４−ジオキサ−２,３−ジヒドロナフタレン−６−イル)エチル]−２−メチルカルバニリド酸−t−ブチル２.３gに、氷冷攪拌下、トリフルオロ酢酸１５.０mlを滴下した。室温にて３０分攪拌を継続した後、過剰のトリフルオロ酢酸を減圧下にて留去、残留物を酢酸エチル１００mlに溶解し、飽和炭酸ナトリウム水溶液１００mlにて洗浄後、飽和食塩水次いで無水硫酸マグネシウムの順で脱水・乾燥後、減圧下にて溶媒を留去した。残留物を酢酸エチル−ヘキサン（２：３）にて溶出するシリカゲルカラムクロマトグラフィー及びアセトニトリル−水(８０：２０)にて溶離する高速液体クロマトグラフにて精製し、目的物０.５gを白色結晶として得た。
融点１４７.５〜１５０.０℃
1H NMR (CDCl3, Me4Si, 300MHz) δ7.33 (s, 1H), 7.24 (d, J=9.9Hz, 1H), 7.05-7.1 (m, 3H), 6.58 (d, J=9.1Hz, 1H), 3.72 (bs, 2H), 3.45 (bs, 1H), 2.12 (s, 3H)。 Step 3; 1- (4-amino-3-methylphenyl) -2,2,2-trifluoro-1- (2,2,3,3-tetrafluoro-1,4-dioxa-2,3-dihydro Preparation of naphthalen-6-yl) ethanol 4- [2,2,2-trifluoro-1-hydroxy-1- (2,2,3,3-tetrafluoro-1,4-dioxa-2,3-dihydro To 2.3 g of naphthalen-6-yl) ethyl] -2-methylcarbanilide acid-t-butyl, 15.0 ml of trifluoroacetic acid was added dropwise with stirring under ice cooling. After stirring for 30 minutes at room temperature, excess trifluoroacetic acid was distilled off under reduced pressure, the residue was dissolved in 100 ml of ethyl acetate, washed with 100 ml of saturated aqueous sodium carbonate solution, saturated brine and then sulfuric anhydride. After dehydration and drying in the order of magnesium, the solvent was distilled off under reduced pressure. The residue was purified by silica gel column chromatography eluting with ethyl acetate-hexane (2: 3) and high performance liquid chromatograph eluting with acetonitrile-water (80:20), and 0.5 g of the desired product was obtained as white crystals. Got as.
Melting point: 147.5-150.0 ° C
1 H NMR (CDCl 3 , Me 4 Si, 300 MHz) δ7.33 (s, 1H), 7.24 (d, J = 9.9 Hz, 1H), 7.05-7.1 (m, 3H), 6.58 (d, J = 9.1 Hz, 1H), 3.72 (bs, 2H), 3.45 (bs, 1H), 2.12 (s, 3H).

工程４；Ｎ1−[４−[２,２,２−トリフルオロ−１−ヒドロキシ−１−(２,２,３,３−テトラフルオロ−１,４−ジオキサ−２,３−ジヒドロナフタレン−６−イル)エチル]−２−メチルフェニル]−３−ヨード−Ｎ2−イソプロピルフタル酸ジアミドの製造
３−ヨード−Ｎ−イソプロピルフタルアミド酸０.１５gのトルエン１０ml溶液に、室温にて攪拌下、トリフルオロ酢酸無水物０.１５gを滴下した。同温度にて３０分間攪拌した後、減圧下に溶媒を留去、残留物をアセトニトリル３mlに溶解し、１−(４−アミノ−３−メチルフェニル)−２,２,２−トリフルオロ−１−(２,２,３,３−テトラフルオロ−１,４−ジオキサ−２,３−ジヒドロナフタレン−６−イル)エタノール０.１５gのアセトニトリル５ml溶液を滴下、滴下終了後、室温にて１時間攪拌を継続した。反応完結後、減圧下にて溶媒を留去、残留物を酢酸エチル−ヘキサン（２：３）にて溶出するシリカゲルカラムクロマトグラフィーにて精製し、目的物０.２５gを無色樹脂状物質として得た。
1H NMR (CDCl3, Me4Si, 300MHz) δ8.42 (s, 1H), 8.10 (d, J=8.8Hz, 1H), 7.9-8.05 (m, 2H), 7.73 (d, J=7.8Hz, 1H), 7.05-7.35 (m, 6H), 5.98 (d, J=8.1Hz, 1H), 4.1-4.25 (m, 1H), 3.69 (s, 1H), 2.28 (s, 3H), 1.16 (d, J=6.6Hz, 6H)。 Step 4; N 1- [4- [2,2,2-trifluoro-1-hydroxy-1- (2,2,3,3-tetrafluoro-1,4-dioxa-2,3-dihydronaphthalene- 6-yl) ethyl] -2-methylphenyl] -3-iodo-N 2 -isopropylphthalic acid diamide 0.15 g of 3-iodo-N-isopropylphthalamic acid in 10 ml of toluene at room temperature with stirring 0.15 g of trifluoroacetic anhydride was added dropwise. After stirring at the same temperature for 30 minutes, the solvent was distilled off under reduced pressure, the residue was dissolved in 3 ml of acetonitrile, and 1- (4-amino-3-methylphenyl) -2,2,2-trifluoro-1 -(2,2,3,3-tetrafluoro-1,4-dioxa-2,3-dihydronaphthalen-6-yl) ethanol (0.15 g) in acetonitrile (5 ml) was added dropwise. Stirring was continued. After completion of the reaction, the solvent was distilled off under reduced pressure, and the residue was purified by silica gel column chromatography eluting with ethyl acetate-hexane (2: 3) to obtain 0.25 g of the desired product as a colorless resinous substance. It was.
1 H NMR (CDCl 3 , Me 4 Si, 300 MHz) δ8.42 (s, 1H), 8.10 (d, J = 8.8 Hz, 1H), 7.9-8.05 (m, 2H), 7.73 (d, J = 7.8 Hz, 1H), 7.05-7.35 (m, 6H), 5.98 (d, J = 8.1Hz, 1H), 4.1-4.25 (m, 1H), 3.69 (s, 1H), 2.28 (s, 3H), 1.16 (d, J = 6.6 Hz, 6H).

合成例５
Ｎ1−[４−[２,２,２−トリフルオロ−１−ヒドロキシ−１−(４−メタンスルホニルオキシフェニル)エチル]−２−メチルフェニル]−３−ヨード−Ｎ2−イソプロピルフタル酸ジアミド（本発明化合物No.1-015）。 Synthesis example 5
N 1- [4- [2,2,2-Trifluoro-1-hydroxy-1- (4-methanesulfonyloxyphenyl) ethyl] -2-methylphenyl] -3-iodo-N 2 -isopropylphthalic acid diamide (Invention compound No. 1-015).

工程１；４'−ヒドロキシ−３−メチル−４−ニトロベンゾフェノンの製造
４'−メトキシ−３−メチル−４−ニトロベンゾフェノン２.０gのジクロロメタン３０ml溶液に、氷冷攪拌下、三臭化ホウ素２.１mlを添加し、室温にて２０時間攪拌した。反応完結後、反応混合物にジエチルエーテル２mlを加えて１０分間攪拌した後、水３０mlに注ぎ有機層を分取、有機層は水洗後、飽和食塩水次いで無水硫酸ナトリウムの順で脱水・乾燥、減圧下にて溶媒を留去した。残留した固体をジイソプロピルエーテル−ヘキサン混合溶媒にて洗浄し、目的物１.８gを淡紫色結晶として得た。
融点１４６.０〜１４８.０℃
1H NMR (CDCl3-DMSO-d6, Me4Si, 300MHz) δ9.71 (bs, 1H), 8.02 (d, J=8.3Hz, 1H), 7.55-7.85 (m, 4H), 6.94 (d, J=8.3Hz, 2H), 2.68 (s, 3H)。 Step 1; Preparation of 4'-hydroxy-3-methyl-4-nitrobenzophenone 4'-methoxy-3-methyl-4-nitrobenzophenone Boron tribromide 2 was added to a solution of 2.0 g of 4'-methoxy-3-methyl-4-nitrobenzophenone in 30 ml of dichloromethane under ice-cooling and stirring. 0.1 ml was added and stirred at room temperature for 20 hours. After completion of the reaction, 2 ml of diethyl ether was added to the reaction mixture and stirred for 10 minutes, then poured into 30 ml of water, and the organic layer was separated. The organic layer was washed with water, dehydrated and dried in the order of saturated saline and then anhydrous sodium sulfate, and reduced pressure. The solvent was distilled off under. The remaining solid was washed with a diisopropyl ether-hexane mixed solvent to obtain 1.8 g of the desired product as pale purple crystals.
Melting point: 146.0-148.0 ° C
1 H NMR (CDCl 3 -DMSO-d 6 , Me 4 Si, 300 MHz) δ9.71 (bs, 1H), 8.02 (d, J = 8.3 Hz, 1H), 7.55-7.85 (m, 4H), 6.94 ( d, J = 8.3Hz, 2H), 2.68 (s, 3H).

工程２；４−(３−メチル−４−ニトロベンゾイル)フェニル＝メタンスルホネートの製造
４'−ヒドロキシ−３−メチル−４−ニトロベンゾフェノン０.５０g及びトリエチルアミン０.２０gのＮ,Ｎ−ジメチルホルムアミド５ml溶液に、氷冷攪拌下、塩化メタンスルホニル０.２２gを添加し、同温度にて２０分間攪拌した。反応完結後、反応混合物を水３０mlに注ぎジエチルエーテル５０mlにて抽出、有機層を飽和食塩水次いで無水硫酸マグネシウムの順で脱水・乾燥、減圧下にて溶媒を留去した。残留物を酢酸エチル−ヘキサン（２：５）にて溶出するシリカゲルカラムクロマトグラフィーにて精製し、目的物０.５４gを褐色油状物質として得た。
1H NMR (CDCl3, Me4Si, 300MHz) δ8.05 (d, J=8.3Hz, 1H), 7.89 (d, J=8.8Hz, 2H), 7.75 (s, 1H), 7.72 (d, J=8.3Hz, 1H), 7.45 (d, J=8.8Hz, 2H), 3.25 (s, 3H), 2.66 (s, 3H)。 Step 2; Preparation of 4- (3-methyl-4-nitrobenzoyl) phenyl methanesulfonate 4 ml of 4'-hydroxy-3-methyl-4-nitrobenzophenone and 0.20 g of triethylamine 5 ml of N, N-dimethylformamide To the solution, 0.22 g of methanesulfonyl chloride was added with stirring under ice cooling, and the mixture was stirred at the same temperature for 20 minutes. After completion of the reaction, the reaction mixture was poured into 30 ml of water and extracted with 50 ml of diethyl ether. The organic layer was dehydrated and dried in the order of saturated brine and then anhydrous magnesium sulfate, and the solvent was distilled off under reduced pressure. The residue was purified by silica gel column chromatography eluting with ethyl acetate-hexane (2: 5) to obtain 0.54 g of the desired product as a brown oily substance.
1 H NMR (CDCl 3 , Me 4 Si, 300 MHz) δ8.05 (d, J = 8.3 Hz, 1H), 7.89 (d, J = 8.8 Hz, 2H), 7.75 (s, 1H), 7.72 (d, J = 8.3Hz, 1H), 7.45 (d, J = 8.8Hz, 2H), 3.25 (s, 3H), 2.66 (s, 3H).

工程３；４−[１−(４−アミノ−３−メチルフェニル)−２,２,２−トリフルオロ−１−ヒドロキシエチル]フェニル＝メタンスルホネートの製造
４−(３−メチル−４−ニトロベンゾイル)フェニル＝メタンスルホネート０.５４g及び(トリフルオロメチル)トリメチルシラン１.５mlの１,２−ジメトキシエタン３ml溶液に、氷冷攪拌下、フッ化セシウム０.０６gを添加し、次いで室温まで昇温、さらに１８時間攪拌を継続した。反応完結後、反応混合物を水３０mlに注ぎジエチルエーテル５０mlにて抽出、有機層を飽和食塩水次いで無水硫酸マグネシウムの順で脱水・乾燥、減圧下にて溶媒を留去した。残留物をテトラヒドロフラン３mlに溶解、室温にて攪拌下、フッ化テトラブチルアンモニウムのテトラヒドロフラン１Ｍ溶液０.３mlを添加し、室温にて１０分間攪拌した。反応完結後、減圧下にて溶媒を留去、水３０mlを加え酢酸エチル３０mlにて抽出、飽和食塩水次いで無水硫酸マグネシウムの順で脱水・乾燥後、乾燥剤を濾別した。濾液に５％パラジウム−カーボン０.２gを添加し、水素雰囲気下、室温にて２０時間攪拌した。反応完結後、パラジウム−カーボンをセライトにて濾別、減圧下にて溶媒を留去し、残留物を酢酸エチル−ヘキサン（１：２〜２：３）にて溶出するシリカゲルカラムクロマトグラフィーにて精製し、目的物０.２４gを白色結晶として得た。
融点１３７.０〜１３９.０℃
1H NMR (CDCl3, Me4Si, 300MHz) δ7.54 (d, J=8.8Hz, 2H), 7.25 (d, J=7.7Hz, 2H), 7.11 (s, 1H), 7.09 (d, J=8.3Hz, 1H), 6.62 (d, J=9.0Hz, 1H), 3.72 (bs, 2H), 3.16 (s, 3H), 2.94 (bs, 1H), 2.14 (s, 3H)。 Step 3; Preparation of 4- [1- (4-Amino-3-methylphenyl) -2,2,2-trifluoro-1-hydroxyethyl] phenyl = methanesulfonate 4- (3-Methyl-4-nitrobenzoyl ) To a solution of 0.54 g of phenyl methanesulfonate and 1.5 ml of (trifluoromethyl) trimethylsilane in 3 ml of 1,2-dimethoxyethane, 0.06 g of cesium fluoride is added with stirring under ice cooling, and then the temperature is raised to room temperature. Stirring was continued for another 18 hours. After completion of the reaction, the reaction mixture was poured into 30 ml of water and extracted with 50 ml of diethyl ether. The organic layer was dehydrated and dried in the order of saturated brine and then anhydrous magnesium sulfate, and the solvent was distilled off under reduced pressure. The residue was dissolved in 3 ml of tetrahydrofuran, and 0.3 ml of a 1M solution of tetrabutylammonium fluoride in tetrahydrofuran was added with stirring at room temperature, followed by stirring at room temperature for 10 minutes. After completion of the reaction, the solvent was distilled off under reduced pressure, 30 ml of water was added, extracted with 30 ml of ethyl acetate, dehydrated and dried in the order of saturated brine and then anhydrous magnesium sulfate, and the desiccant was filtered off. To the filtrate was added 0.2 g of 5% palladium-carbon, and the mixture was stirred at room temperature for 20 hours in a hydrogen atmosphere. After completion of the reaction, palladium-carbon was filtered off through Celite, the solvent was distilled off under reduced pressure, and the residue was purified by silica gel column chromatography eluting with ethyl acetate-hexane (1: 2 to 2: 3). Purification gave 0.24 g of the desired product as white crystals.
Melting point 137.0-139.0C
1 H NMR (CDCl 3 , Me 4 Si, 300 MHz) δ7.54 (d, J = 8.8Hz, 2H), 7.25 (d, J = 7.7Hz, 2H), 7.11 (s, 1H), 7.09 (d, J = 8.3Hz, 1H), 6.62 (d, J = 9.0Hz, 1H), 3.72 (bs, 2H), 3.16 (s, 3H), 2.94 (bs, 1H), 2.14 (s, 3H).

工程４；Ｎ1−[４−[２,２,２−トリフルオロ−１−ヒドロキシ−１−(４−メタンスルホニルオキシフェニル)エチル]−２−メチルフェニル]−３−ヨード−Ｎ2−イソプロピルフタル酸ジアミドの製造
３−ヨード−Ｎ−イソプロピルフタルアミド酸０.１０gのトルエン５ml溶液に、室温にて攪拌下、トリフルオロ酢酸無水物０.０９gを滴下した。同温度にて３０分間攪拌した後、減圧下に溶媒を留去、残留物をアセトニトリル４mlに溶解し、４−[１−(４−アミノ−３−メチルフェニル)−２,２,２−トリフルオロ−１−ヒドロキシエチル]フェニル＝メタンスルホネート０.１１g及びトリフルオロ酢酸１滴を添加、室温にて１８時間攪拌した。反応完結後、減圧下にて溶媒を留去、残留物を酢酸エチル−ヘキサン（１：１）にて溶出するシリカゲルカラムクロマトグラフィーにて精製し、目的物０.２０gを無色樹脂状固体として得た。
融点１１１.０〜１１４.０℃
1H NMR (CDCl3, Me4Si, 300MHz) δ8.39 (bs, 1H), 8.08 (d, J=9.1Hz, 1H), 7.97 (d, J=8.0Hz, 1H), 7.79 (d, J=7.1Hz, 1H), 7.54 (d, J=8.8Hz, 2H), 7.15-7.4 (m, 5H), 5.17 (d, J=8.0Hz, 1H), 4.15-4.3 (m, 1H), 3.17 (s, 3H), 3.07 (s, 1H), 2.30 (s, 3H), 1.17 (d, J=6.6Hz, 6H)。 Step 4: N 1- [4- [2,2,2-trifluoro-1-hydroxy-1- (4-methanesulfonyloxyphenyl) ethyl] -2-methylphenyl] -3-iodo-N 2 -isopropyl Preparation of phthalic acid diamide 0.09 g of trifluoroacetic anhydride was added dropwise to a solution of 0.10 g of 3-iodo-N-isopropylphthalamic acid in 5 ml of toluene with stirring at room temperature. After stirring at the same temperature for 30 minutes, the solvent was distilled off under reduced pressure, the residue was dissolved in 4 ml of acetonitrile, and 4- [1- (4-amino-3-methylphenyl) -2,2,2-trimethyl was dissolved. 0.11 g of fluoro-1-hydroxyethyl] phenyl methanesulfonate and 1 drop of trifluoroacetic acid were added and stirred at room temperature for 18 hours. After completion of the reaction, the solvent was distilled off under reduced pressure, and the residue was purified by silica gel column chromatography eluting with ethyl acetate-hexane (1: 1) to obtain 0.20 g of the desired product as a colorless resinous solid. It was.
Melting point: 111.0-114.0 ° C
1 H NMR (CDCl 3 , Me 4 Si, 300 MHz) δ 8.39 (bs, 1H), 8.08 (d, J = 9.1Hz, 1H), 7.97 (d, J = 8.0Hz, 1H), 7.79 (d, J = 7.1Hz, 1H), 7.54 (d, J = 8.8Hz, 2H), 7.15-7.4 (m, 5H), 5.17 (d, J = 8.0Hz, 1H), 4.15-4.3 (m, 1H), 3.17 (s, 3H), 3.07 (s, 1H), 2.30 (s, 3H), 1.17 (d, J = 6.6Hz, 6H).

合成例６
Ｎ1−[４−[３−(４−クロロフェニル)−１−ヒドロキシ−１−トリフルオロメチル−２−プロペニル]−２−メチルフェニル]−３−ヨード−Ｎ2−イソプロピルフタル酸ジアミド（本発明化合物No.2-018）。 Synthesis Example 6
N 1- [4- [3- (4-Chlorophenyl) -1-hydroxy-1-trifluoromethyl-2-propenyl] -2-methylphenyl] -3-iodo-N 2 -isopropylphthalic acid diamide (invention) Compound No. 2-018).

工程１；４−[３−(４−クロロフェニル)−１−ヒドロキシ−１−トリフルオロメチル−２−プロペニル]−２−メチルカルバニリド酸−t−ブチルの製造
窒素雰囲気下の４−ヨード−２−メチルカルバニリド酸−t−ブチル１０.０gのt−ブチルメチルエーテル１４０ml溶液に、−６０℃にて攪拌下、n−ブチルリチウム(１.５８Ｍヘキサン溶液)４１.８mlを滴下し、滴下終了後０℃に昇温、さらに３０分間攪拌した。次いで、この反応混合物を−７８℃に冷却、４−(４−クロロフェニル)−１,１,１−トリフルオロ−３−ブテン−２−オン７.０gを添加し、徐々に０℃まで昇温、さらに同温度にて３０分間攪拌を継続した。反応完結後、反応混合物を飽和塩化アンモニウム水溶液３００mlに注ぎ有機層を分取、水層は酢酸エチル１００mlにて抽出した。有機層を合わせ無水硫酸マグネシウムで乾燥、減圧下にて溶媒を留去した。残留物を酢酸エチル−ヘキサン（１：９〜２：３）にて溶出するシリカゲルカラムクロマトグラフィー及びクロロホルムにて溶出するアルミナカラムクロマトグラフィーにて精製し、目的物４.２gを無色油状物質として得た。
1H NMR (CDCl3, Me4Si, 300MHz) δ7.90 (d, J=8.1Hz, 1H), 7.25-7.5 (m, 6H), 6.82 (d, J=16.0Hz, 1H), 6.63 (d, J=16.0Hz, 1H), 6.31 (bs, 1H), 2.73 (s, 1H), 2.27 (s, 3H), 1.52 (s, 9H)。 Step 1; Preparation of 4- [3- (4-Chlorophenyl) -1-hydroxy-1-trifluoromethyl-2-propenyl] -2-methylcarbanilide acid t-butyl 4-iodo- under nitrogen atmosphere To a solution of 10.0 g of 2-methylcarbanilide acid-t-butyl in 140 ml of t-butylmethyl ether, 41.8 ml of n-butyllithium (1.58 M hexane solution) was added dropwise with stirring at -60 ° C. After completion of the dropwise addition, the temperature was raised to 0 ° C. and further stirred for 30 minutes. The reaction mixture was then cooled to −78 ° C., 7.0 g of 4- (4-chlorophenyl) -1,1,1-trifluoro-3-buten-2-one was added, and the temperature was gradually raised to 0 ° C. Further, stirring was continued for 30 minutes at the same temperature. After completion of the reaction, the reaction mixture was poured into 300 ml of saturated aqueous ammonium chloride solution, the organic layer was separated, and the aqueous layer was extracted with 100 ml of ethyl acetate. The organic layers were combined and dried over anhydrous magnesium sulfate, and the solvent was distilled off under reduced pressure. The residue was purified by silica gel column chromatography eluting with ethyl acetate-hexane (1: 9-2: 3) and alumina column chromatography eluting with chloroform to obtain 4.2 g of the objective product as a colorless oily substance. It was.
1 H NMR (CDCl 3 , Me 4 Si, 300 MHz) δ7.90 (d, J = 8.1 Hz, 1H), 7.25-7.5 (m, 6H), 6.82 (d, J = 16.0 Hz, 1H), 6.63 ( d, J = 16.0Hz, 1H), 6.31 (bs, 1H), 2.73 (s, 1H), 2.27 (s, 3H), 1.52 (s, 9H).

工程２；１−(４−アミノ−３−メチルフェニル)−３−(４−クロロフェニル)−１−トリフルオロメチル−２−プロペン−１−オールの製造
４−[３−(４−クロロフェニル)−１−ヒドロキシ−１−トリフルオロメチル−２−プロペニル]−２−メチルカルバニリド酸−t−ブチル４.２gに、氷冷攪拌下、トリフルオロ酢酸８.０mlを滴下した。室温にて３０分攪拌を継続した後、氷冷下、飽和炭酸カリウム水溶液１５０mlを加えクロロホルム１００mlにて抽出、有機層を無水硫酸ナトリウムにて乾燥後、減圧下にて溶媒を留去した。残留した固体をジイソプロピルエーテル１０mlにて洗浄し、目的物２.４gを白色結晶として得た。
融点１２６.５〜１２９.０℃
1H NMR (CDCl3, Me4Si, 300MHz) δ7.15-7.4 (m, 6H), 6.83 (d, J=16.0Hz, 1H), 6.55-6.75 (m, 2H), 2.8-3.5 (broad, 3H), 2.17 (s, 3H)。 Step 2: Production of 1- (4-amino-3-methylphenyl) -3- (4-chlorophenyl) -1-trifluoromethyl-2-propen-1-ol 4- [3- (4-chlorophenyl)- 8.0 ml of trifluoroacetic acid was added dropwise to 4.2 g of 1-hydroxy-1-trifluoromethyl-2-propenyl] -2-methylcarbanilide acid-t-butyl with stirring under ice cooling. After stirring at room temperature for 30 minutes, 150 ml of saturated aqueous potassium carbonate solution was added under ice-cooling, extracted with 100 ml of chloroform, the organic layer was dried over anhydrous sodium sulfate, and the solvent was distilled off under reduced pressure. The remaining solid was washed with 10 ml of diisopropyl ether to obtain 2.4 g of the desired product as white crystals.
Melting point: 126.5-129.0 ° C
1 H NMR (CDCl 3 , Me 4 Si, 300 MHz) δ7.15-7.4 (m, 6H), 6.83 (d, J = 16.0Hz, 1H), 6.55-6.75 (m, 2H), 2.8-3.5 (broad , 3H), 2.17 (s, 3H).

工程３；Ｎ1−[４−[３−(４−クロロフェニル)−１−ヒドロキシ−１−トリフルオロメチル−２−プロペニル]−２−メチルフェニル]−３−ヨード−Ｎ2−イソプロピルフタル酸ジアミドの製造
３−ヨード−Ｎ−イソプロピルフタルアミド酸１.１７gのトルエン２０ml溶液に、室温にて攪拌下、トリフルオロ酢酸無水物０.８６gを滴下した。同温度にて１時間攪拌した後、減圧下に溶媒を留去、残留物をアセトニトリル１０mlに溶解し、１−(４−アミノ−３−メチルフェニル)−３−(４−クロロフェニル)−１−トリフルオロメチル−２−プロペン−１−オール１.０gを添加、室温にて３時間攪拌を継続した。反応完結後、減圧下にて溶媒を留去、残留物を酢酸エチル−ヘキサン（１：９〜２：３）にて溶出するシリカゲルカラムクロマトグラフィーにて精製し、目的物１.５０gを白色結晶として得た。
融点１０８.０〜１１３.０℃
1H NMR (CDCl3, Me4Si, 400MHz) δ8.38 (s, 1H), 8.07 (d, J=8.8Hz, 1H), 7.96 (d, J=8.0Hz, 1H), 7.78 (d, J=8.0Hz, 1H), 7.15-7.5 (m, 7H), 6.83 (d, J=16.0Hz, 1H), 6.64 (d, J=16.0Hz, 1H), 5.85 (d, J=8.4Hz, 1H), 4.15-4.3 (m, 1H), 2.99 (s, 1H), 2.34 (s, 3H), 1.16 (d, J=6.4Hz, 6H)。 Step 3; N 1 - [4- [ 3- (4- chlorophenyl) -1-hydroxy-1-trifluoromethyl-2-propenyl] -2-methylphenyl] -3-iodo -N 2 - isopropyl phthalic acid diamide Preparation of 3-iodo-N-isopropylphthalamic acid 1.86 g of trifluoroacetic anhydride 0.86 g was added dropwise to a 20 ml toluene solution at room temperature with stirring. After stirring at the same temperature for 1 hour, the solvent was distilled off under reduced pressure, the residue was dissolved in 10 ml of acetonitrile, and 1- (4-amino-3-methylphenyl) -3- (4-chlorophenyl) -1- 1.0 g of trifluoromethyl-2-propen-1-ol was added and stirring was continued for 3 hours at room temperature. After completion of the reaction, the solvent was distilled off under reduced pressure, and the residue was purified by silica gel column chromatography eluting with ethyl acetate-hexane (1: 9 to 2: 3) to give 1.50 g of the desired product as white crystals. Got as.
Melting point: 108.0-113.0 ° C
1 H NMR (CDCl 3 , Me 4 Si, 400 MHz) δ8.38 (s, 1H), 8.07 (d, J = 8.8Hz, 1H), 7.96 (d, J = 8.0Hz, 1H), 7.78 (d, J = 8.0Hz, 1H), 7.15-7.5 (m, 7H), 6.83 (d, J = 16.0Hz, 1H), 6.64 (d, J = 16.0Hz, 1H), 5.85 (d, J = 8.4Hz, 1H), 4.15-4.3 (m, 1H), 2.99 (s, 1H), 2.34 (s, 3H), 1.16 (d, J = 6.4Hz, 6H).

合成例７
Ｎ1−[４−[１−(４−クロロフェニル)−２,２,２−トリフルオロ−１−メトキシエチル]−２−メチルフェニル]−３−ヨード−Ｎ2−イソプロピルフタル酸ジアミド（本発明化合物No.3-002）。 Synthesis example 7
N 1 - [4- [1- ( 4- chlorophenyl) -2,2,2-trifluoro-1-methoxyethyl] -2-methylphenyl] -3-iodo -N 2 - isopropyl phthalic acid diamide (present invention Compound No. 3-002).

工程１；４−[１−(４−クロロフェニル)−２,２,２−トリフルオロ−１−ヒドロキシエチル]−２−メチルカルバニリド酸−t−ブチルの製造
窒素雰囲気下の４−ヨード−２−メチルカルバニリド酸−t−ブチル３.０gのt−ブチルメチルエーテル４０ml溶液に、−５０℃にて攪拌下、n−ブチルリチウム(１.５８Ｍヘキサン溶液)１２.５mlを滴下し、滴下終了後０℃に昇温、さらに３０分間攪拌した。次いで、この反応混合物を−７８℃に冷却、４'−クロロ−２,２,２−トリフルオロアセトフェノン１.８８gを添加し、徐々に０℃まで昇温、さらに同温度にて３０分間攪拌を継続した。反応完結後、反応混合物に飽和塩化アンモニウム水溶液１００mlを加え有機層を分取、水層は酢酸エチル１００mlにて抽出した。有機層を合わせ無水硫酸マグネシウムで乾燥、減圧下にて溶媒を留去した。残留物を酢酸エチル−ヘキサン（１：９〜２：３）にて溶出するシリカゲルカラムクロマトグラフィーにて精製し、目的物２.９６gを無色透明油状物質として得た。
1H NMR (CDCl3, Me4Si, 300MHz) δ7.86 (d, J=8.7Hz, 1H), 7.40 (d, J=8.4Hz, 2H), 7.15-7.35 (m, 4H), 6.30 (bs, 1H), 2.93 (s, 1H), 2.22 (s, 3H), 1.52 (s, 9H)。 Step 1; Preparation of 4- [1- (4-chlorophenyl) -2,2,2-trifluoro-1-hydroxyethyl] -2-methylcarbanilide acid t-butyl 4-iodo- under nitrogen atmosphere To a solution of 3.0 g of 2-methylcarbanilide acid-t-butyl in 40 ml of t-butylmethyl ether, 12.5 ml of n-butyllithium (1.58 M hexane solution) was added dropwise with stirring at -50 ° C. After completion of the dropwise addition, the temperature was raised to 0 ° C. and further stirred for 30 minutes. The reaction mixture was then cooled to -78 ° C, 1.88 g of 4'-chloro-2,2,2-trifluoroacetophenone was added, the temperature was gradually raised to 0 ° C, and the mixture was further stirred at the same temperature for 30 minutes. Continued. After completion of the reaction, 100 ml of saturated aqueous ammonium chloride solution was added to the reaction mixture, the organic layer was separated, and the aqueous layer was extracted with 100 ml of ethyl acetate. The organic layers were combined and dried over anhydrous magnesium sulfate, and the solvent was distilled off under reduced pressure. The residue was purified by silica gel column chromatography eluting with ethyl acetate-hexane (1: 9-2: 3) to obtain 2.96 g of the desired product as a colorless transparent oily substance.
1 H NMR (CDCl 3 , Me 4 Si, 300 MHz) δ7.86 (d, J = 8.7 Hz, 1H), 7.40 (d, J = 8.4 Hz, 2H), 7.15-7.35 (m, 4H), 6.30 ( bs, 1H), 2.93 (s, 1H), 2.22 (s, 3H), 1.52 (s, 9H).

工程２；１−(４−アミノ−３−メチルフェニル)−１−(４−クロロフェニル)−２,２,２−トリフルオロエタノールの製造
４−[１−(４−クロロフェニル)−２,２,２−トリフルオロ−１−ヒドロキシエチル]−２−メチルカルバニリド酸−t−ブチル２.９６gに、氷冷攪拌下、トリフルオロ酢酸６.０mlを滴下した。室温にて２０分攪拌を継続した後、氷冷下、飽和炭酸カリウム水溶液７０mlを加えクロロホルム１００mlにて抽出、有機層を無水硫酸ナトリウムにて乾燥後、減圧下にて溶媒を留去し、目的物１.８０gを褐色固体として得た。
融点１５７.０〜１６０.５℃
1H NMR (CDCl3, Me4Si, 300MHz) δ7.45 (d, J=8.8Hz, 2H), 7.28 (d, J=8.8Hz, 2H), 7.05-7.15 (m, 2H), 6.60 (d, J=8.3Hz, 1H), 5.03 (bs, 1H), 3.74 (bs, 2H), 2.12 (s, 3H)。 Step 2: Preparation of 1- (4-amino-3-methylphenyl) -1- (4-chlorophenyl) -2,2,2-trifluoroethanol 4- [1- (4-chlorophenyl) -2,2, To 2.96 g of 2-trifluoro-1-hydroxyethyl] -2-methylcarbanilide acid-t-butyl, 6.0 ml of trifluoroacetic acid was added dropwise with stirring under ice cooling. After stirring for 20 minutes at room temperature, 70 ml of saturated aqueous potassium carbonate solution was added under ice cooling, extracted with 100 ml of chloroform, the organic layer was dried over anhydrous sodium sulfate, and the solvent was distilled off under reduced pressure. 1.80 g of product was obtained as a brown solid.
Melting point 157.0-160.5 ° C
1 H NMR (CDCl 3 , Me 4 Si, 300 MHz) δ7.45 (d, J = 8.8Hz, 2H), 7.28 (d, J = 8.8Hz, 2H), 7.05-7.15 (m, 2H), 6.60 ( d, J = 8.3Hz, 1H), 5.03 (bs, 1H), 3.74 (bs, 2H), 2.12 (s, 3H).

工程３；４−[１−(４−クロロフェニル)−２,２,２−トリフルオロ−１−メトキシエチル]−２−メチルアニリンの製造
１−(４−アミノ−３−メチルフェニル)−１−(４−クロロフェニル)−２,２,２−トリフルオロエタノール０.５gのＮ,Ｎ−ジメチルホルムアミド３ml溶液に、氷冷攪拌下、５５％油性水素化ナトリウム０.０７３gを添加し、室温にて２０分間攪拌、次いでヨウ化メチル０.２４gを添加し、同温度にてさらに２時間攪拌を継続した。反応完結後、反応混合物を氷水２０mlに注ぎ酢酸エチル３０mlにて抽出、有機層を無水硫酸マグネシウムで乾燥後、減圧下にて溶媒を留去した。残留物を酢酸エチル−ヘキサン（２：３）にて溶出するシリカゲルカラムクロマトグラフィーにて精製し、目的物０.４４gを褐色油状物質として得た。
1H NMR (CDCl3, Me4Si, 300MHz) δ7.2-7.4 (m, 4H), 6.9-7.1 (m, 3H), 6.62 (d, J=8.3Hz, 1H), 3.71 (bs, 2H), 3.27 (s, 3H), 2.14 (s, 3H)。 Step 3; Preparation of 4- [1- (4-Chlorophenyl) -2,2,2-trifluoro-1-methoxyethyl] -2-methylaniline 1- (4-Amino-3-methylphenyl) -1- To a solution of 0.5 g of (4-chlorophenyl) -2,2,2-trifluoroethanol in 3 ml of N, N-dimethylformamide was added 0.073 g of 55% oily sodium hydride with stirring on ice, and at room temperature. The mixture was stirred for 20 minutes, then 0.24 g of methyl iodide was added, and stirring was continued for another 2 hours at the same temperature. After completion of the reaction, the reaction mixture was poured into 20 ml of ice water, extracted with 30 ml of ethyl acetate, the organic layer was dried over anhydrous magnesium sulfate, and the solvent was distilled off under reduced pressure. The residue was purified by silica gel column chromatography eluting with ethyl acetate-hexane (2: 3) to obtain 0.44 g of the desired product as a brown oily substance.
1 H NMR (CDCl 3 , Me 4 Si, 300 MHz) δ7.2-7.4 (m, 4H), 6.9-7.1 (m, 3H), 6.62 (d, J = 8.3Hz, 1H), 3.71 (bs, 2H ), 3.27 (s, 3H), 2.14 (s, 3H).

工程４；Ｎ1−[４−[１−(４−クロロフェニル)−２,２,２−トリフルオロ−１−メトキシエチル]−２−メチルフェニル]−３−ヨード−Ｎ2−イソプロピルフタル酸ジアミドの製造
３−ヨード−Ｎ−イソプロピルフタルアミド酸０.２５gのトルエン５ml溶液に、室温にて攪拌下、トリフルオロ酢酸無水物０.１８gを滴下した。同温度にて１時間攪拌した後、減圧下に溶媒を留去、残留物をアセトニトリル３.０mlに溶解し、４−[１−(４−クロロフェニル)−２,２,２−トリフルオロ−１−メトキシエチル]−２−メチルアニリン０.２１gを添加、室温にて１４時間攪拌を継続した。反応完結後、析出した結晶を濾別、少量のアセトニトリルで洗浄することにより、目的物０.２gを白色結晶として得た。
融点２１１.５〜２１４.０℃
1H NMR (CDCl3, Me4Si, 300MHz) δ8.35 (bs, 1H), 8.09 (d, J=8.8Hz, 1H), 7.97 (d, J=7.6Hz, 1H), 7.79 (d, J=8.0Hz, 1H), 7.15-7.35 (m, 7H), 5.83 (d, J=8.0Hz, 1H), 4.15-4.3 (m, 1H), 3.30 (s, 3H), 2.31 (s, 3H), 1.17 (d, J=6.6Hz, 6H)。 Step 4; N 1 - [4- [ 1- (4- chlorophenyl) -2,2,2-trifluoro-1-methoxyethyl] -2-methylphenyl] -3-iodo -N 2 - isopropyl phthalic acid diamide Preparation of 0.18 g of trifluoroacetic anhydride was added dropwise to a solution of 0.25 g of 3-iodo-N-isopropylphthalamic acid in 5 ml of toluene with stirring at room temperature. After stirring at the same temperature for 1 hour, the solvent was distilled off under reduced pressure, the residue was dissolved in 3.0 ml of acetonitrile, and 4- [1- (4-chlorophenyl) -2,2,2-trifluoro-1 -Methoxyethyl] -2-methylaniline (0.21 g) was added, and stirring was continued at room temperature for 14 hours. After completion of the reaction, the precipitated crystals were separated by filtration and washed with a small amount of acetonitrile to obtain 0.2 g of the desired product as white crystals.
Melting point 211.5-214.0 ° C
1 H NMR (CDCl 3 , Me 4 Si, 300 MHz) δ 8.35 (bs, 1H), 8.09 (d, J = 8.8Hz, 1H), 7.97 (d, J = 7.6Hz, 1H), 7.79 (d, J = 8.0Hz, 1H), 7.15-7.35 (m, 7H), 5.83 (d, J = 8.0Hz, 1H), 4.15-4.3 (m, 1H), 3.30 (s, 3H), 2.31 (s, 3H ), 1.17 (d, J = 6.6 Hz, 6H).

合成例８
Ｎ1−[４−[２−(４−クロロフェノキシ)−１−ヒドロキシ−１−トリフルオロメチルエチル]−２−メチルフェニル]−３−ヨード−Ｎ2−イソプロピルフタル酸ジアミド（本発明化合物No.2-004）。 Synthesis example 8
N 1- [4- [2- (4-Chlorophenoxy) -1-hydroxy-1-trifluoromethylethyl] -2-methylphenyl] -3-iodo-N 2 -isopropylphthalic acid diamide (Compound No. of the present invention) .2-004).

工程１；４−[２−(４−クロロフェノキシ)−１−ヒドロキシ−１−トリフルオロメチルエチル]−２−メチルカルバニリド酸−t−ブチルの製造
２−メチル−４−(１−トリフルオロメチルオキシラン−１−イル)カルバニリド酸−t−ブチル２.０g及び４−クロロフェノール１.５gのＮ,Ｎ−ジメチルホルムアミド３０ml溶液に、氷冷攪拌下、６０％油性水素化ナトリウム０.４５gを添加し、室温にて２４時間攪拌した。反応完結後、反応混合物を氷水１５０mlに注ぎジエチルエーテル１００mlにて抽出、有機層を飽和食塩水次いで無水硫酸マグネシウムの順で脱水・乾燥、減圧下にて溶媒を留去した。残留物を酢酸エチル−ヘキサン（１：４）にて溶出するシリカゲルカラムクロマトグラフィーにて精製し、目的物２.１gを無色油状物質として得た。 Step 1; Preparation of 4- [2- (4-Chlorophenoxy) -1-hydroxy-1-trifluoromethylethyl] -2-methylcarbanilide acid-t-butyl 2-Methyl-4- (1-tri To a solution of 2.0 g of fluoromethyloxiran-1-yl) carbanilide-t-butyl and 1.5 g of 4-chlorophenol in 30 ml of N, N-dimethylformamide was added 0.45 g of 60% oily sodium hydride under ice-cooling and stirring. Was added and stirred at room temperature for 24 hours. After completion of the reaction, the reaction mixture was poured into 150 ml of ice water and extracted with 100 ml of diethyl ether. The organic layer was dehydrated and dried in the order of saturated brine and then anhydrous magnesium sulfate, and the solvent was distilled off under reduced pressure. The residue was purified by silica gel column chromatography eluting with ethyl acetate-hexane (1: 4) to obtain 2.1 g of the objective product as a colorless oil.

工程２；Ｎ1−[４−[２−(４−クロロフェノキシ)−１−ヒドロキシ−１−トリフルオロメチルエチル]−２−メチルフェニル]−３−ヨード−Ｎ2−イソプロピルフタル酸ジアミドの製造
４−[２−(４−クロロフェノキシ)−１−ヒドロキシ−１−トリフルオロメチルエチル]−２−メチルカルバニリド酸−t−ブチル１.０gに、氷冷攪拌下、トリフルオロ酢酸５.０mlを滴下した。室温にて１０分攪拌を継続した後、減圧下にて過剰のトリフルオロ酢酸を留去し、粗製の１−(４−アミノ−３−メチルフェニル)−２−(４−クロロフェノキシ)−１−トリフルオロメチルエタノールを得た。 Step 2; N 1 - [4- [ 2- (4- chlorophenoxy) -1-hydroxy-1-trifluoromethyl-ethyl] -2-methylphenyl] -3-iodo -N 2 - preparation of isopropyl phthalic diamides To 1.0 g of 4- [2- (4-chlorophenoxy) -1-hydroxy-1-trifluoromethylethyl] -2-methylcarbanilide acid-t-butyl, trifluoroacetic acid 5. 0 ml was added dropwise. After stirring for 10 minutes at room temperature, excess trifluoroacetic acid was distilled off under reduced pressure to obtain crude 1- (4-amino-3-methylphenyl) -2- (4-chlorophenoxy) -1 -Trifluoromethylethanol was obtained.

３−ヨード−Ｎ−イソプロピルフタルアミド酸０.８gのトルエン１０ml溶液に、室温にて攪拌下、トリフルオロ酢酸無水物０.８gを滴下した。同温度にて３０分間攪拌した後、減圧下に溶媒を留去、残留物をアセトニトリル２０mlに溶解し、上記粗製の１−(４−アミノ−３−メチルフェニル)−２−(４−クロロフェノキシ)−１−トリフルオロメチルエタノールを添加、室温にて３時間攪拌を継続した。反応完結後、減圧下にて溶媒を留去、残留物を酢酸エチル−クロロホルム（２：３）にて溶出するシリカゲルカラムクロマトグラフィーにて精製し、目的物０.７gを白色結晶として得た。
融点９０.０〜９５.０℃。 To a 10 ml toluene solution of 0.8 g 3-iodo-N-isopropylphthalamic acid, 0.8 g trifluoroacetic anhydride was added dropwise at room temperature with stirring. After stirring at the same temperature for 30 minutes, the solvent was distilled off under reduced pressure, the residue was dissolved in 20 ml of acetonitrile, and the above crude 1- (4-amino-3-methylphenyl) -2- (4-chlorophenoxy) was dissolved. ) -1-Trifluoromethylethanol was added and stirring was continued at room temperature for 3 hours. After completion of the reaction, the solvent was distilled off under reduced pressure, and the residue was purified by silica gel column chromatography eluting with ethyl acetate-chloroform (2: 3) to obtain 0.7 g of the desired product as white crystals.
Melting point 90.0-95.0 ° C.

合成例９
Ｎ1−[４−[２−(４−クロロフェノキシ)−２,２−ジフルオロ−１−ヒドロキシ−１−トリフルオロメチルエチル]−２−メチルフェニル]−３−ヨード−Ｎ2−イソプロピルフタル酸ジアミド（本発明化合物No.2-008）。 Synthesis Example 9
N 1- [4- [2- (4-chlorophenoxy) -2,2-difluoro-1-hydroxy-1-trifluoromethylethyl] -2-methylphenyl] -3-iodo-N 2 -isopropylphthalic acid Diamide (the present compound No. 2-008).

工程１；１−(２−ブロモ−１,１,２,３,３,３−ヘキサフルオロプロピルオキシ)−４−クロロベンゼンの製造
２,２−ジブロモ−１,１,２,３,３,３−ヘキサフルオロプロパン２０.０g及び４−クロロフェノール７.０gのＮ,Ｎ−ジメチルホルムアミド１００ml溶液に、氷冷攪拌下、６０％油性水素化ナトリウム２.２gを添加し、室温にて１２時間攪拌した。反応完結後、反応混合物を氷水３００mlに注ぎジエチルエーテル１５０mlにて抽出、有機層を飽和食塩水次いで無水硫酸マグネシウムの順で脱水・乾燥、減圧下にて溶媒を留去した。残留物を酢酸エチル−ヘキサン（１：４）にて溶出するシリカゲルカラムクロマトグラフィーにて精製し、目的物１８.０gを無色油状物質として得た。 Step 1; Preparation of 1- (2-bromo-1,1,2,3,3,3-hexafluoropropyloxy) -4-chlorobenzene 2,2-dibromo-1,1,2,3,3,3 -To a solution of 20.0 g of hexafluoropropane and 7.0 g of 4-chlorophenol in 100 ml of N, N-dimethylformamide was added 2.2 g of 60% oily sodium hydride under ice-cooling and stirring for 12 hours at room temperature. did. After completion of the reaction, the reaction mixture was poured into 300 ml of ice water and extracted with 150 ml of diethyl ether. The organic layer was dehydrated and dried in the order of saturated brine and then anhydrous magnesium sulfate, and the solvent was distilled off under reduced pressure. The residue was purified by silica gel column chromatography eluting with ethyl acetate-hexane (1: 4) to obtain 18.0 g of the desired product as a colorless oil.

工程２；４−[２−(４−クロロフェノキシ)−１,２,２−トリフルオロ−１−トリフルオロメチルエチル]−２−メチルアニリンの製造
１−(２−ブロモ−１,１,２,３,３,３−ヘキサフルオロプロピルオキシ)−４−クロロベンゼン５.０g及びo−トルイジン１.５gのジメチルスルホキシド５０ml溶液に、攪拌下、炭酸水素ナトリウム１.８g及び亜ジチオン酸ナトリウム３.８gを添加し、７０℃にて３時間攪拌した。反応完結後、反応混合物を氷水３００mlに注ぎジエチルエーテル１５０mlにて抽出、有機層を飽和食塩水次いで無水硫酸マグネシウムの順で脱水・乾燥、減圧下にて溶媒を留去した。残留物を酢酸エチル−ヘキサン（１：４）にて溶出するシリカゲルカラムクロマトグラフィーにて精製し、目的物３.８gを無色油状物質として得た。 Step 2: Preparation of 4- [2- (4-chlorophenoxy) -1,2,2-trifluoro-1-trifluoromethylethyl] -2-methylaniline 1- (2-Bromo-1,1,2 , 3,3,3-hexafluoropropyloxy) -4-chlorobenzene (5.0 g) and o-toluidine (1.5 g) in 50 ml of dimethyl sulfoxide, with stirring, 1.8 g of sodium bicarbonate and 3.8 g of sodium dithionite. Was added and stirred at 70 ° C. for 3 hours. After completion of the reaction, the reaction mixture was poured into 300 ml of ice water and extracted with 150 ml of diethyl ether. The organic layer was dehydrated and dried in the order of saturated brine and then anhydrous magnesium sulfate, and the solvent was distilled off under reduced pressure. The residue was purified by silica gel column chromatography eluting with ethyl acetate-hexane (1: 4) to obtain 3.8 g of the desired product as a colorless oil.

工程３；１−(４−アミノ−３−メチルフェニル)−２−(４−クロロフェノキシ)−２,２−ジフルオロ−１−トリフルオロメチルエタノールの製造
４−[２−(４−クロロフェノキシ)−１,２,２−トリフルオロ−１−トリフルオロメチルエチル]−２−メチルアニリン２.０gの１,４−ジオキサン２０ml溶液に水酸化カリウム３.０gを添加し、加熱還流下にて２時間攪拌した。反応完結後、減圧下にて溶媒を留去、残留物を氷水１００mlに投入しジエチルエーテル１００mlにて抽出、有機層を飽和食塩水次いで無水硫酸マグネシウムの順で脱水・乾燥、減圧下にて溶媒を留去した。残留物を酢酸エチル−ヘキサン（２：３）にて溶出するシリカゲルカラムクロマトグラフィーにて精製し、目的物０.６gを淡黄色油状物質として得た。 Step 3; Preparation of 1- (4-amino-3-methylphenyl) -2- (4-chlorophenoxy) -2,2-difluoro-1-trifluoromethylethanol 4- [2- (4-chlorophenoxy) -1,2,2-trifluoro-1-trifluoromethylethyl] -2-methylaniline in an amount of 2.0 g of 1,4-dioxane in 20 ml was added with 3.0 g of potassium hydroxide and heated under reflux for 2 Stir for hours. After completion of the reaction, the solvent was distilled off under reduced pressure, the residue was poured into 100 ml of ice water and extracted with 100 ml of diethyl ether, and the organic layer was dehydrated and dried in the order of saturated brine and anhydrous magnesium sulfate, and the solvent was removed under reduced pressure. Was distilled off. The residue was purified by silica gel column chromatography eluting with ethyl acetate-hexane (2: 3) to obtain 0.6 g of the desired product as a pale yellow oily substance.

工程４；Ｎ1−[４−[３−(４−クロロフェニル)−１−ヒドロキシ−１−トリフルオロメチル−２−プロペニル]−２−メチルフェニル]−３−ヨード−Ｎ2−イソプロピルフタル酸ジアミドの製造
３−ヨード−Ｎ−イソプロピルフタルアミド酸０.６gのトルエン５ml溶液に、室温にて攪拌下、トリフルオロ酢酸無水物０.６gを滴下した。同温度にて３０分間攪拌した後、減圧下に溶媒を留去、残留物をアセトニトリル１０mlに溶解し、１−(４−アミノ−３−メチルフェニル)−２−(４−クロロフェノキシ)−２,２−ジフルオロ−１−トリフルオロメチルエタノール０.５gを添加、室温にて５時間攪拌を継続した。反応完結後、減圧下にて溶媒を留去、残留物を酢酸エチル−クロロホルム（２：３）にて溶出するシリカゲルカラムクロマトグラフィーにて精製し、目的物０.３gを無色結晶として得た。
融点６５.０〜７５.０℃。 Step 4; N 1 - [4- [ 3- (4- chlorophenyl) -1-hydroxy-1-trifluoromethyl-2-propenyl] -2-methylphenyl] -3-iodo -N 2 - isopropyl phthalic acid diamide Preparation of 0.6 g of trifluoroacetic anhydride was added dropwise to a solution of 0.6 g of 3-iodo-N-isopropylphthalamic acid in 5 ml of toluene with stirring at room temperature. After stirring at the same temperature for 30 minutes, the solvent was distilled off under reduced pressure, and the residue was dissolved in 10 ml of acetonitrile to give 1- (4-amino-3-methylphenyl) -2- (4-chlorophenoxy) -2. , 2-difluoro-1-trifluoromethylethanol 0.5 g was added and stirring was continued at room temperature for 5 hours. After completion of the reaction, the solvent was distilled off under reduced pressure, and the residue was purified by silica gel column chromatography eluting with ethyl acetate-chloroform (2: 3) to obtain 0.3 g of the objective product as colorless crystals.
Melting point 65.0-75.0 ° C.

合成例１０
Ｎ1−(２,２−ジフルオロ−３−ヒドロキシ−５−メチル−３−トリフルオロメチル−２,３−ジヒドロベンゾフラン−６−イル)−３−ヨード−Ｎ2−イソプロピルフタル酸ジアミド（本発明化合物No.4-002）。 Synthesis Example 10
N 1- (2,2-difluoro-3-hydroxy-5-methyl-3-trifluoromethyl-2,3-dihydrobenzofuran-6-yl) -3-iodo-N 2 -isopropylphthalic acid diamide (invention) Compound No. 4-002).

工程１；１−(２−ブロモ−１,１,２,３,３,３−ヘキサフルオロプロピルオキシ)−４−メチル−３−ニトロベンゼンの製造
２,２−ジブロモ−１,１,２,３,３,３−ヘキサフルオロプロパン１０.０g及び４−メチル−３−ニトロフェノール５.０gのＮ,Ｎ−ジメチルホルムアミド１００ml溶液に、氷冷攪拌下、６０％油性水素化ナトリウム１.４gを添加し、室温にて１２時間攪拌した。反応完結後、反応混合物を氷水３００mlに注ぎジエチルエーテル１５０mlにて抽出、有機層を飽和食塩水次いで無水硫酸マグネシウムの順で脱水・乾燥、減圧下にて溶媒を留去した。残留物を酢酸エチル−ヘキサン（１：４）にて溶出するシリカゲルカラムクロマトグラフィーにて精製し、目的物８.０gを淡黄色油状物質として得た。 Step 1; Preparation of 1- (2-bromo-1,1,2,3,3,3-hexafluoropropyloxy) -4-methyl-3-nitrobenzene 2,2-dibromo-1,1,2,3 To a solution of 10.0 g of 1,3,3-hexafluoropropane and 5.0 g of 4-methyl-3-nitrophenol in 100 ml of N, N-dimethylformamide was added 1.4 g of 60% oily sodium hydride under ice-cooling. And stirred at room temperature for 12 hours. After completion of the reaction, the reaction mixture was poured into 300 ml of ice water and extracted with 150 ml of diethyl ether. The organic layer was dehydrated and dried in the order of saturated brine and then anhydrous magnesium sulfate, and the solvent was distilled off under reduced pressure. The residue was purified by silica gel column chromatography eluting with ethyl acetate-hexane (1: 4) to obtain 8.0 g of the desired product as a pale yellow oily substance.

工程２；５−(２−ブロモ−１,１,２,３,３,３−ヘキサフルオロプロピルオキシ)−２−メチルアニリンの製造
１−(２−ブロモ−１,１,２,３,３,３−ヘキサフルオロプロピルオキシ)−４−メチル−３−ニトロベンゼン８.０gのエタノール１００ml溶液に、室温にて攪拌下、塩化スズ二水和物９.５g及び濃塩酸１５mlを添加し、同温度にて１２時間攪拌した。反応完結後、減圧下にて溶媒を留去、残留物を２Ｎ水酸化ナトリウム水溶液１００mlに投入しジエチルエーテル１００mlにて抽出、有機層を飽和食塩水次いで無水硫酸マグネシウムの順で脱水・乾燥、減圧下にて溶媒を留去した。残留物を酢酸エチル−ヘキサン（１：４）にて溶出するシリカゲルカラムクロマトグラフィーにて精製し、目的物６.０gを淡黄色油状物質として得た。 Step 2; Preparation of 5- (2-Bromo-1,1,2,3,3,3-hexafluoropropyloxy) -2-methylaniline 1- (2-Bromo-1,1,2,3,3 , 3-Hexafluoropropyloxy) -4-methyl-3-nitrobenzene To a solution of 8.0 g of ethanol in 100 ml of ethanol at room temperature, 9.5 g of tin chloride dihydrate and 15 ml of concentrated hydrochloric acid were added at the same temperature. For 12 hours. After completion of the reaction, the solvent was distilled off under reduced pressure, the residue was poured into 100 ml of 2N aqueous sodium hydroxide solution and extracted with 100 ml of diethyl ether, and the organic layer was dehydrated, dried and dried over anhydrous magnesium sulfate in this order. The solvent was distilled off under. The residue was purified by silica gel column chromatography eluting with ethyl acetate-hexane (1: 4) to obtain 6.0 g of the desired product as a pale yellow oily substance.

工程３；６−アミノ−２,２,３−トリフルオロ−５−メチル−３−トリフルオロメチル−２,３−ジヒドロベンゾフランの製造
５−(２−ブロモ−１,１,２,３,３,３−ヘキサフルオロプロピルオキシ)−２−メチルアニリン６.０gのジメチルスルホキシド５０ml溶液に、攪拌下、炭酸水素ナトリウム２.２g及び亜ジチオン酸ナトリウム４.５gを添加し、７０℃にて３時間攪拌した。反応完結後、反応混合物を氷水３００mlに注ぎジエチルエーテル１５０mlにて抽出、有機層を飽和食塩水次いで無水硫酸マグネシウムの順で脱水・乾燥、減圧下にて溶媒を留去した。残留物を酢酸エチル−ヘキサン（３：７）にて溶出するシリカゲルカラムクロマトグラフィーにて精製し、目的物３.０gを無色油状物質として得た。 Step 3; Preparation of 6-amino-2,2,3-trifluoro-5-methyl-3-trifluoromethyl-2,3-dihydrobenzofuran 5- (2-bromo-1,1,2,3,3 , 3-Hexafluoropropyloxy) -2-methylaniline to a solution of 6.0 g of dimethyl sulfoxide with stirring, 2.2 g of sodium hydrogen carbonate and 4.5 g of sodium dithionite were added and stirred at 70 ° C. for 3 hours. Stir. After completion of the reaction, the reaction mixture was poured into 300 ml of ice water and extracted with 150 ml of diethyl ether. The organic layer was dehydrated and dried in the order of saturated brine and then anhydrous magnesium sulfate, and the solvent was distilled off under reduced pressure. The residue was purified by silica gel column chromatography eluting with ethyl acetate-hexane (3: 7) to obtain 3.0 g of the objective product as a colorless oil.

工程４；６−アミノ−２,２−ジフルオロ−３−ヒドロキシ−５−メチル−３−トリフルオロメチル−２,３−ジヒドロベンゾフランの製造
６−アミノ−２,２,３−トリフルオロ−５−メチル−３−トリフルオロメチル−２,３−ジヒドロベンゾフラン１.０gを酢酸エチル−メタノール（７：３）にて溶出するアルミナカラムクロマトグラフィーにて処理し、目的物０.６gを白色結晶として得た。 Step 4: Preparation of 6-amino-2,2-difluoro-3-hydroxy-5-methyl-3-trifluoromethyl-2,3-dihydrobenzofuran 6-amino-2,2,3-trifluoro-5- Treatment of 1.0 g of methyl-3-trifluoromethyl-2,3-dihydrobenzofuran with alumina column chromatography eluting with ethyl acetate-methanol (7: 3) gave 0.6 g of the desired product as white crystals. It was.

工程５；Ｎ1−(２,２−ジフルオロ−３−ヒドロキシ−５−メチル−３−トリフルオロメチル−２,３−ジヒドロベンゾフラン−６−イル)−３−ヨード−Ｎ2−イソプロピルフタル酸ジアミドの製造
３−ヨード−Ｎ−イソプロピルフタルアミド酸０.６gのトルエン５ml溶液に、室温にて攪拌下、トリフルオロ酢酸無水物０.６gを滴下した。同温度にて３０分間攪拌した後、減圧下に溶媒を留去、残留物をアセトニトリル１０mlに溶解し、６−アミノ−２,２−ジフルオロ−３−ヒドロキシ−５−メチル−３−トリフルオロメチル−２,３−ジヒドロベンゾフラン０.５gを添加、室温にて５時間攪拌を継続した。反応完結後、減圧下にて溶媒を留去、残留物を酢酸エチル−クロロホルム（１：１）にて溶出するシリカゲルカラムクロマトグラフィーにて精製し、目的物０.４gを無色結晶として得た。
融点１４４.０〜１４６.０℃。 Step 5; N 1 - (2,2- difluoro-3-hydroxy-5-methyl-3-trifluoromethyl-2,3-dihydrobenzofuran-6-yl) -3-iodo -N 2 - isopropyl phthalic acid diamide Preparation of 0.6 g of trifluoroacetic anhydride was added dropwise to a solution of 0.6 g of 3-iodo-N-isopropylphthalamic acid in 5 ml of toluene with stirring at room temperature. After stirring at the same temperature for 30 minutes, the solvent was distilled off under reduced pressure, the residue was dissolved in 10 ml of acetonitrile, and 6-amino-2,2-difluoro-3-hydroxy-5-methyl-3-trifluoromethyl was dissolved. 0.5 g of -2,3-dihydrobenzofuran was added and stirring was continued for 5 hours at room temperature. After completion of the reaction, the solvent was distilled off under reduced pressure, and the residue was purified by silica gel column chromatography eluting with ethyl acetate-chloroform (1: 1) to obtain 0.4 g of the objective product as colorless crystals.
Melting point: 144.0-146.0 ° C.

本発明化合物は、前記製造法及び実施例に準じて製造することができる。そのような化合物の例を第６表〜第１０表に示すが、本発明はこれらのみに限定されるものではない。   This invention compound can be manufactured according to the said manufacturing method and an Example. Examples of such compounds are shown in Tables 6 to 10, but the present invention is not limited to these.

尚、表中i-Prとの記載はイソプロピル基を表し、以下同様にs-Buはセカンダリーブチル基を、t-Buはターシャリーブチル基を、Phはフェニル基を、2-Naphは2-ナフチル基をそれぞれ表し、
表中L-15b〜L-45eで表される芳香族複素環は、それぞれ下記の構造を表す。 In the table, the description of i-Pr represents an isopropyl group. Similarly, s-Bu represents a secondary butyl group, t-Bu represents a tertiary butyl group, Ph represents a phenyl group, and 2-Naph represents 2-butyl. Each represents a naphthyl group,
The aromatic heterocycles represented by L-15b to L-45e in the table each represent the following structure.

Figure 2005126418
Figure 2005126418

例えば、[(D-15b)CF３]の表記は、1-メチル-5-トリフルオロメチルピラゾール-3-イル基を表し、[CH２(L-36a)]の表記は、1,2,4-トリアゾール-1-イルメチル基を表す。 For example, the notation [(D-15b) CF 3 ] represents a 1-methyl-5-trifluoromethylpyrazol-3-yl group, and the notation [CH 2 (L-36a)] is 1,2, Represents a 4-triazol-1-ylmethyl group.

また、表中、*1は「樹脂状」を、*2は「油状」をそれぞれ意味する。
第６表 In the table, * 1 means “resinous” and * 2 means “oily”.
Table 6

Figure 2005126418
Figure 2005126418

―――――――――――――――――――――――――――――――――――――――
No. (X)m R3 R4 (Z)p1 m.p.（℃）
―――――――――――――――――――――――――――――――――――――――
1-001 3-I i-Pr CH3 4-Cl 177.0-179.0
1-002 3-I i-Pr i-Pr 4-Cl 112.0-115.0
1-003 3-I i-Pr CF3 4-F 192.0-194.0
1-004 3-I i-Pr CF3 3-Cl *1
1-005 3-I i-Pr CF3 4-Cl 107.5-109.5
1-006 3-I i-Pr CF3 4-Br 110.0-113.0
1-007 3-I i-Pr CF3 4-CF3 112.0-114.0
1-008 3-I i-Pr CF3 4-OCH3 102.0-105.0
1-009 3-I i-Pr CF3 4-OCF3 *1
1-010 3-I i-Pr CF3 4-OCF2Br 97.0-102.5
1-011 3-I i-Pr CF3 4-OCF2CHF2 98.0-101.0
1-012 3-I i-Pr CF3 4-OCF2CHFCF3 98.0-101.0
1-013 3-I i-Pr CF3 4-OCF2CHFOCF3 93.0-96.0
1-014 3-I i-Pr CF3 4-OCF2CHFOCF2CF2CF3 78.0-80.0
1-015 3-I i-Pr CF3 4-OSO2CH3 111.0-114.0
1-016 3-I i-Pr CF3 3-O(L-45e) 103.5-107.0
1-017 3-I i-Pr CF3 4-O(L-45e) 107.0-109.0
1-018 3-I i-Pr CF3 4-SCH3 100.0-107.5
1-019 3-I i-Pr CF3 4-SO2CH3 150.0-162.0
1-020 3-I i-Pr CF3 2-F-4-Cl *1
1-021 3-I i-Pr CF3 2,4-Cl2 120.0-124.0
1-022 3-I i-Pr CF3 3,4-Cl2 112.0-113.0
1-023 3-I i-Pr CF3 3,5-Cl2 195.0-197.0
1-024 3-I i-Pr CF3 3,4-Br2 125.0-131.5
1-025 3-I i-Pr CF3 3-Cl-4-OCHF2 *1
1-026 3-I i-Pr CF3 3-CH3-4-OCF2CHFOCF3 92.0-94.0
1-027 3-I i-Pr CF3 3-OCF2O-4 *1
1-028 3-I i-Pr CF3 3-OCF2CF2O-4 *1
1-029 3-I i-Pr CF3 3,5-Cl2-4-OCH3 110.0-116.5
1-030 3-I i-Pr C(O)OCH3 4-Cl 133.5-135.0
1-031 3-I s-Bu CF3 4-OCF3 *1
1-032 3-I t-Bu CF3 4-OCF3 151.0-154.0
1-033 3-I CH(CH3)CH2SCH3 i-Pr 4-Cl 105.0-107.0
1-034 3-I CH(CH3)CH2SCH3 CF3 4-F 127.0-130.0
1-035 3-I CH(CH3)CH2SCH3 CF3 3-Cl *1
1-036 3-I CH(CH3)CH2SCH3 CF3 4-Cl 95.5-99.0
1-037 3-I CH(CH3)CH2SCH3 CF3 4-Bu-t 107.0-111.0
1-038 3-I CH(CH3)CH2SCH3 CF3 4-CF3 101.0-103.0
1-039 3-I CH(CH3)CH2SCH3 CF3 4-OCH3 97.0-99.0
1-040 3-I CH(CH3)CH2SCH3 CF3 4-OCF3 112.0-115.0
1-041 3-I CH(CH3)CH2SCH3 CF3 4-OCF2Br *1
1-042 3-I CH(CH3)CH2SCH3 CF3 4-OCF2CHF2 93.0-96.0
1-043 3-I CH(CH3)CH2SCH3 CF3 4-OCF2CHFCF3 91.0-95.0
1-044 3-I CH(CH3)CH2SCH3 CF3 4-OCF2CHFOCF3 86.0-89.0
1-045 3-I CH(CH3)CH2SCH3 CF3 4-OCF2CHFOCF2CF2CF3 71.0-72.0
1-046 3-I CH(CH3)CH2SCH3 CF3 4-OSO2CH3 97.0-100.0
1-047 3-I CH(CH3)CH2SCH3 CF3 3-O(L-45e) *1
1-048 3-I CH(CH3)CH2SCH3 CF3 4-O(L-45e) 105.0-107.0
1-049 3-I CH(CH3)CH2SCH3 CF3 4-SO2CH3 117.0-120.0
1-050 3-I CH(CH3)CH2SCH3 CF3 2-F-4-Cl 116.0-120.0
1-051 3-I CH(CH3)CH2SCH3 CF3 2,4-Cl2 112.0-116.0
1-052 3-I CH(CH3)CH2SCH3 CF3 3,4-Cl2 99.0-103.0
1-053 3-I CH(CH3)CH2SCH3 CF3 3,5-Cl2 121.0-123.5
1-054 3-I CH(CH3)CH2SCH3 CF3 3,4-Br2 108.0-110.0
1-055 3-I CH(CH3)CH2SCH3 CF3 3-Cl-4-OCHF2 *1
1-056 3-I CH(CH3)CH2SCH3 CF3 3-Cl-4-OCF3 83.0-89.0
1-057 3-I CH(CH3)CH2SCH3 CF3 3-CH3-4-OCF2CHFOCF3 86.0-89.0
1-058 3-I CH(CH3)CH2SCH3 CF3 3-OCF2O-4 *1
1-059 3-I CH(CH3)CH2SCH3 CF3 3-OCF2CF2O-4 *1
1-060 3-I CH(CH3)CH2SCH3 CF3 3,5-Cl2-4-OCH3 110.0-113.5
1-061 3-I CH(CH3)CH2SCH3 C(O)OCH3 4-Cl *1
1-062 3-I CH(CH3)CH2S(O)CH3 CF3 3-Cl 182.0-184.0
1-063 3-I CH(CH3)CH2S(O)CH3 CF3 4-OCF3 229.0-231.0
1-064 3-I CH(CH3)CH2SO2CH3 i-Pr 4-Cl 122.0-124.0
1-065 3-I CH(CH3)CH2SO2CH3 CF3 4-F 142.0-144.0
1-066 3-I CH(CH3)CH2SO2CH3 CF3 4-Cl 180.0-184.0
1-067 3-I CH(CH3)CH2SO2CH3 CF3 4-CF3 111.0-113.0
1-068 3-I CH(CH3)CH2SO2CH3 CF3 4-OCH3 123.0-126.0
1-069 3-I CH(CH3)CH2SO2CH3 CF3 4-OCF3 218.0-220.0
1-070 3-I CH(CH3)CH2SO2CH3 CF3 4-OCF2Br 115.0-117.5
1-071 3-I CH(CH3)CH2SO2CH3 CF3 4-OCF2CHF2 112.0-115.0
1-072 3-I CH(CH3)CH2SO2CH3 CF3 4-OCF2CHFCF3 144.0-146.0
1-073 3-I CH(CH3)CH2SO2CH3 CF3 4-OCF2CHFOCF3 102.0-105.0
1-074 3-I CH(CH3)CH2SO2CH3 CF3 4-O(L-45e) 123.0-124.0
1-075 3-I CH(CH3)CH2SO2CH3 CF3 2-F-4-Cl 228.0-230.0
1-076 3-I CH(CH3)CH2SO2CH3 CF3 2,4-Cl2 125.0-128.0
1-077 3-I CH(CH3)CH2SO2CH3 CF3 3,4-Cl2 112.0-114.0
1-078 3-I CH(CH3)CH2SO2CH3 CF3 3,5-Cl2 127.0-132.0
1-079 3-I CH(CH3)CH2SO2CH3 CF3 3,4-Br2 133.0-145.0
1-080 3-I CH(CH3)CH2SO2CH3 CF3 3-Cl-4-OCHF2 *1
1-081 3-I CH(CH3)CH2SO2CH3 CF3 3-CH3-4-OCF2CHFOCF3 116.0-118.0
1-082 3-I CH(CH3)CH2SO2CH3 CF3 3-OCF2O-4 193.0-203.0
1-083 3-I CH(CH3)CH2SO2CH3 CF3 3-OCF2CF2O-4 *1
1-084 3-I C(CH3)2CH2SCH3 CF3 4-Cl 172.0-175.0
1-085 3-I C(CH3)2CH2SCH3 CF3 4-OCF3 *1
1-086 3-I C(CH3)2CH2SCH3 CF3 3,4-Cl2 96.0-98.0
1-087 3-I C(CH3)2CH2SO2CH3 CF3 4-Cl 126.0-128.0
1-088 3-I C(CH3)2CH2SO2CH3 CF3 4-OCF3 *1
1-089 3-I C(CH3)2CH2SO2CH3 CF3 3,4-Cl2 109.0-113.0
1-090 3-I C(CH3)2C≡CH CF3 4-OCF3 *1
―――――――――――――――――――――――――――――――――――――――
第７表 ―――――――――――――――――――――――――――――――――――――――
No. (X) m R 3 R 4 (Z) p1 mp (℃)
―――――――――――――――――――――――――――――――――――――――
1-001 3-I i-Pr CH 3 4-Cl 177.0-179.0
1-002 3-I i-Pr i-Pr 4-Cl 112.0-115.0
1-003 3-I i-Pr CF 3 4-F 192.0-194.0
1-004 3-I i-Pr CF 3 3-Cl * 1
1-005 3-I i-Pr CF 3 4-Cl 107.5-109.5
1-006 3-I i-Pr CF 3 4-Br 110.0-113.0
1-007 3-I i-Pr CF 3 4-CF 3 112.0-114.0
1-008 3-I i-Pr CF 3 4-OCH 3 102.0-105.0
1-009 3-I i-Pr CF 3 4-OCF 3 * 1
1-010 3-I i-Pr CF 3 4-OCF 2 Br 97.0-102.5
1-011 3-I i-Pr CF 3 4-OCF 2 CHF 2 98.0-101.0
1-012 3-I i-Pr CF 3 4-OCF 2 CHFCF 3 98.0-101.0
1-013 3-I i-Pr CF 3 4-OCF 2 CHFOCF 3 93.0-96.0
1-014 3-I i-Pr CF 3 4-OCF 2 CHFOCF 2 CF 2 CF 3 78.0-80.0
1-015 3-I i-Pr CF 3 4-OSO 2 CH 3 111.0-114.0
1-016 3-I i-Pr CF 3 3-O (L-45e) 103.5-107.0
1-017 3-I i-Pr CF 3 4-O (L-45e) 107.0-109.0
1-018 3-I i-Pr CF 3 4-SCH 3 100.0-107.5
1-019 3-I i-Pr CF 3 4-SO 2 CH 3 150.0-162.0
1-020 3-I i-Pr CF 3 2-F-4-Cl * 1
1-021 3-I i-Pr CF 3 2,4-Cl 2 120.0-124.0
1-022 3-I i-Pr CF 3 3,4-Cl 2 112.0-113.0
1-023 3-I i-Pr CF 3 3,5-Cl 2 195.0-197.0
1-024 3-I i-Pr CF 3 3,4-Br 2 125.0-131.5
1-025 3-I i-Pr CF 3 3-Cl-4-OCHF 2 * 1
1-026 3-I i-Pr CF 3 3-CH 3 -4-OCF 2 CHFOCF 3 92.0-94.0
1-027 3-I i-Pr CF 3 3-OCF 2 O-4 * 1
1-028 3-I i-Pr CF 3 3-OCF 2 CF 2 O-4 * 1
1-029 3-I i-Pr CF 3 3,5-Cl 2 -4-OCH 3 110.0-116.5
1-030 3-I i-Pr C (O) OCH 3 4-Cl 133.5-135.0
1-031 3-I s-Bu CF 3 4-OCF 3 * 1
1-032 3-I t-Bu CF 3 4-OCF 3 151.0-154.0
1-033 3-I CH (CH 3 ) CH 2 SCH 3 i-Pr 4-Cl 105.0-107.0
1-034 3-I CH (CH 3 ) CH 2 SCH 3 CF 3 4-F 127.0-130.0
1-035 3-I CH (CH 3 ) CH 2 SCH 3 CF 3 3-Cl * 1
1-036 3-I CH (CH 3 ) CH 2 SCH 3 CF 3 4-Cl 95.5-99.0
1-037 3-I CH (CH 3 ) CH 2 SCH 3 CF 3 4-Bu-t 107.0-111.0
1-038 3-I CH (CH 3 ) CH 2 SCH 3 CF 3 4-CF 3 101.0-103.0
1-039 3-I CH (CH 3 ) CH 2 SCH 3 CF 3 4-OCH 3 97.0-99.0
1-040 3-I CH (CH 3 ) CH 2 SCH 3 CF 3 4-OCF 3 112.0-115.0
1-041 3-I CH (CH 3 ) CH 2 SCH 3 CF 3 4-OCF 2 Br * 1
1-042 3-I CH (CH 3 ) CH 2 SCH 3 CF 3 4-OCF 2 CHF 2 93.0-96.0
1-043 3-I CH (CH 3 ) CH 2 SCH 3 CF 3 4-OCF 2 CHFCF 3 91.0-95.0
1-044 3-I CH (CH 3 ) CH 2 SCH 3 CF 3 4-OCF 2 CHFOCF 3 86.0-89.0
1-045 3-I CH (CH 3 ) CH 2 SCH 3 CF 3 4-OCF 2 CHFOCF 2 CF 2 CF 3 71.0-72.0
1-046 3-I CH (CH 3 ) CH 2 SCH 3 CF 3 4-OSO 2 CH 3 97.0-100.0
1-047 3-I CH (CH 3 ) CH 2 SCH 3 CF 3 3-O (L-45e) * 1
1-048 3-I CH (CH 3 ) CH 2 SCH 3 CF 3 4-O (L-45e) 105.0-107.0
1-049 3-I CH (CH 3 ) CH 2 SCH 3 CF 3 4-SO 2 CH 3 117.0-120.0
1-050 3-I CH (CH 3 ) CH 2 SCH 3 CF 3 2-F-4-Cl 116.0-120.0
1-051 3-I CH (CH 3 ) CH 2 SCH 3 CF 3 2,4-Cl 2 112.0-116.0
1-052 3-I CH (CH 3 ) CH 2 SCH 3 CF 3 3,4-Cl 2 99.0-103.0
1-053 3-I CH (CH 3 ) CH 2 SCH 3 CF 3 3,5-Cl 2 121.0-123.5
1-054 3-I CH (CH 3 ) CH 2 SCH 3 CF 3 3,4-Br 2 108.0-110.0
1-055 3-I CH (CH 3 ) CH 2 SCH 3 CF 3 3-Cl-4-OCHF 2 * 1
1-056 3-I CH (CH 3 ) CH 2 SCH 3 CF 3 3-Cl-4-OCF 3 83.0-89.0
1-057 3-I CH (CH 3 ) CH 2 SCH 3 CF 3 3-CH 3 -4-OCF 2 CHFOCF 3 86.0-89.0
1-058 3-I CH (CH 3 ) CH 2 SCH 3 CF 3 3-OCF 2 O-4 * 1
1-059 3-I CH (CH 3 ) CH 2 SCH 3 CF 3 3-OCF 2 CF 2 O-4 * 1
1-060 3-I CH (CH 3 ) CH 2 SCH 3 CF 3 3,5-Cl 2 -4-OCH 3 110.0-113.5
1-061 3-I CH (CH 3 ) CH 2 SCH 3 C (O) OCH 3 4-Cl * 1
1-062 3-I CH (CH 3 ) CH 2 S (O) CH 3 CF 3 3-Cl 182.0-184.0
1-063 3-I CH (CH 3 ) CH 2 S (O) CH 3 CF 3 4-OCF 3 229.0-231.0
1-064 3-I CH (CH 3 ) CH 2 SO 2 CH 3 i-Pr 4-Cl 122.0-124.0
1-065 3-I CH (CH 3 ) CH 2 SO 2 CH 3 CF 3 4-F 142.0-144.0
1-066 3-I CH (CH 3 ) CH 2 SO 2 CH 3 CF 3 4-Cl 180.0-184.0
1-067 3-I CH (CH 3 ) CH 2 SO 2 CH 3 CF 3 4-CF 3 111.0-113.0
1-068 3-I CH (CH 3 ) CH 2 SO 2 CH 3 CF 3 4-OCH 3 123.0-126.0
1-069 3-I CH (CH 3 ) CH 2 SO 2 CH 3 CF 3 4-OCF 3 218.0-220.0
1-070 3-I CH (CH 3 ) CH 2 SO 2 CH 3 CF 3 4-OCF 2 Br 115.0-117.5
1-071 3-I CH (CH 3 ) CH 2 SO 2 CH 3 CF 3 4-OCF 2 CHF 2 112.0-115.0
1-072 3-I CH (CH 3 ) CH 2 SO 2 CH 3 CF 3 4-OCF 2 CHFCF 3 144.0-146.0
1-073 3-I CH (CH 3 ) CH 2 SO 2 CH 3 CF 3 4-OCF 2 CHFOCF 3 102.0-105.0
1-074 3-I CH (CH 3 ) CH 2 SO 2 CH 3 CF 3 4-O (L-45e) 123.0-124.0
1-075 3-I CH (CH 3 ) CH 2 SO 2 CH 3 CF 3 2-F-4-Cl 228.0-230.0
1-076 3-I CH (CH 3 ) CH 2 SO 2 CH 3 CF 3 2,4-Cl 2 125.0-128.0
1-077 3-I CH (CH 3 ) CH 2 SO 2 CH 3 CF 3 3,4-Cl 2 112.0-114.0
1-078 3-I CH (CH 3 ) CH 2 SO 2 CH 3 CF 3 3,5-Cl 2 127.0-132.0
1-079 3-I CH (CH 3 ) CH 2 SO 2 CH 3 CF 3 3,4-Br 2 133.0-145.0
1-080 3-I CH (CH 3 ) CH 2 SO 2 CH 3 CF 3 3-Cl-4-OCHF 2 * 1
1-081 3-I CH (CH 3 ) CH 2 SO 2 CH 3 CF 3 3-CH 3 -4-OCF 2 CHFOCF 3 116.0-118.0
1-082 3-I CH (CH 3 ) CH 2 SO 2 CH 3 CF 3 3-OCF 2 O-4 193.0-203.0
1-083 3-I CH (CH 3 ) CH 2 SO 2 CH 3 CF 3 3-OCF 2 CF 2 O-4 * 1
1-084 3-IC (CH 3 ) 2 CH 2 SCH 3 CF 3 4-Cl 172.0-175.0
1-085 3-IC (CH 3 ) 2 CH 2 SCH 3 CF 3 4-OCF 3 * 1
1-086 3-IC (CH 3 ) 2 CH 2 SCH 3 CF 3 3,4-Cl 2 96.0-98.0
1-087 3-IC (CH 3 ) 2 CH 2 SO 2 CH 3 CF 3 4-Cl 126.0-128.0
1-088 3-IC (CH 3 ) 2 CH 2 SO 2 CH 3 CF 3 4-OCF 3 * 1
1-089 3-IC (CH 3 ) 2 CH 2 SO 2 CH 3 CF 3 3,4-Cl 2 109.0-113.0
1-090 3-IC (CH 3 ) 2 C≡CH CF 3 4-OCF 3 * 1
―――――――――――――――――――――――――――――――――――――――
Table 7

Figure 2005126418
Figure 2005126418

―――――――――――――――――――――――――――――――――――――――
No. (X)m R3 R4 R5 m.p.（℃）
―――――――――――――――――――――――――――――――――――――――
2-001 3-I i-Pr CH3 (L-45c)CF3 *1
2-002 3-I i-Pr CF3 CH2CH2(Ph-4-Cl) 103.5-106.0
2-003 3-I i-Pr CF3 CH2OCH3 181.0-184.0
2-004 3-I i-Pr CF3 CH2O(Ph-4-Cl) 90.0-95.0
2-005 3-I i-Pr CF3 CH2OC(O)(Ph-4-Cl) 180.0-183.0
2-006 3-I i-Pr CF3 CF2O(Ph-2-Cl) 86.0-88.0
2-007 3-I i-Pr CF3 CF2O(Ph-3-Cl) 82.0-85.0
2-008 3-I i-Pr CF3 CF2O(Ph-4-Cl) 65.0-75.0
2-009 3-I i-Pr CF3 CH2S(Ph-4-Cl) 80.0-83.0
2-010 3-I i-Pr CF3 CH2SO2(Ph-4-Cl) 111.0-113.0
2-011 3-I i-Pr CF3 CH2N(CH3)2 204.0-207.0
2-012 3-I i-Pr CF3 CH2NH(Ph-4-Cl) 120.0-122.0
2-013 3-I i-Pr CF3 CF2C(O)OEt *1
2-014 3-I i-Pr CF3 CH2(L-36a) 149.0-152.0
2-015 3-I i-Pr CF3 C(O)OEt 177.0-178.0
2-016 3-I i-Pr CF3 CH=CH(Ph-4-F) 109.0-111.0
2-017 3-I i-Pr CF3 CH=CH(Ph-3-Cl) *1
2-018 3-I i-Pr CF3 CH=CH(Ph-4-Cl) 108.0-113.0
2-019 3-I i-Pr CF3 CH=CH(Ph-4-OCF3) 104.0-108.5
2-020 3-I i-Pr CF3 CH=CH(Ph-4-SCH3) *1
2-021 3-I i-Pr CF3 CH=CH(Ph-4-SO2CH3) 133.0-138.0
2-022 3-I i-Pr CF3 CH=CH(Ph-3,4-Cl2) 111.0-113.0
2-023 3-I i-Pr CF3 2-Naph 113.0-117.0
2-024 3-I i-Pr CF3 (L-45c)CF3 107.0-110.0
2-025 3-I CH(CH3)CH2SCH3 CF3 CF2O(Ph-4-Cl) *1
2-026 3-I CH(CH3)CH2SCH3 CF3 CH=CH(Ph-4-F) 98.0-111.0
2-027 3-I CH(CH3)CH2SCH3 CF3 CH=CH(Ph-3-Cl) *1
2-028 3-I CH(CH3)CH2SCH3 CF3 CH=CH(Ph-4-Cl) 103.5-108.0
2-029 3-I CH(CH3)CH2SCH3 CF3 CH=CH(Ph-4-OCF3) *1
2-030 3-I CH(CH3)CH2SCH3 CF3 CH=CH(Ph-3,4-Cl2) 98.0-101.0
2-031 3-I CH(CH3)CH2SCH3 CF3 2-Naph *1
2-032 3-I CH(CH3)CH2SCH3 CF3 (L-15b)CF3 94.0-97.0
2-033 3-I CH(CH3)CH2SO2CH3 CF3 CF2O(Ph-4-Cl) 131.5-135.0
2-034 3-I CH(CH3)CH2SO2CH3 CF3 CH=CH(Ph-4-F) 123.0-125.0
2-035 3-I CH(CH3)CH2SO2CH3 CF3 CH=CH(Ph-4-Cl) 128.0-130.5
2-036 3-I CH(CH3)CH2SO2CH3 CF3 CH=CH(Ph-4-OCF3) 120.5-125.0
2-037 3-I CH(CH3)CH2SO2CH3 CF3 CH=CH(Ph-3,4-Cl2) 124.0-128.0
2-038 3-I CH(CH3)CH2SO2CH3 CF3 2-Naph *1
―――――――――――――――――――――――――――――――――――――――
第８表 ―――――――――――――――――――――――――――――――――――――――
No. (X) m R 3 R 4 R 5 mp (℃)
―――――――――――――――――――――――――――――――――――――――
2-001 3-I i-Pr CH 3 (L-45c) CF 3 * 1
2-002 3-I i-Pr CF 3 CH 2 CH 2 (Ph-4-Cl) 103.5-106.0
2-003 3-I i-Pr CF 3 CH 2 OCH 3 181.0-184.0
2-004 3-I i-Pr CF 3 CH 2 O (Ph-4-Cl) 90.0-95.0
2-005 3-I i-Pr CF 3 CH 2 OC (O) (Ph-4-Cl) 180.0-183.0
2-006 3-I i-Pr CF 3 CF 2 O (Ph-2-Cl) 86.0-88.0
2-007 3-I i-Pr CF 3 CF 2 O (Ph-3-Cl) 82.0-85.0
2-008 3-I i-Pr CF 3 CF 2 O (Ph-4-Cl) 65.0-75.0
2-009 3-I i-Pr CF 3 CH 2 S (Ph-4-Cl) 80.0-83.0
2-010 3-I i-Pr CF 3 CH 2 SO 2 (Ph-4-Cl) 111.0-113.0
2-011 3-I i-Pr CF 3 CH 2 N (CH 3 ) 2 204.0-207.0
2-012 3-I i-Pr CF 3 CH 2 NH (Ph-4-Cl) 120.0-122.0
2-013 3-I i-Pr CF 3 CF 2 C (O) OEt * 1
2-014 3-I i-Pr CF 3 CH 2 (L-36a) 149.0-152.0
2-015 3-I i-Pr CF 3 C (O) OEt 177.0-178.0
2-016 3-I i-Pr CF 3 CH = CH (Ph-4-F) 109.0-111.0
2-017 3-I i-Pr CF 3 CH = CH (Ph-3-Cl) * 1
2-018 3-I i-Pr CF 3 CH = CH (Ph-4-Cl) 108.0-113.0
2-019 3-I i-Pr CF 3 CH = CH (Ph-4-OCF 3 ) 104.0-108.5
2-020 3-I i-Pr CF 3 CH = CH (Ph-4-SCH 3 ) * 1
2-021 3-I i-Pr CF 3 CH = CH (Ph-4-SO 2 CH 3 ) 133.0-138.0
2-022 3-I i-Pr CF 3 CH = CH (Ph-3,4-Cl 2 ) 111.0-113.0
2-023 3-I i-Pr CF 3 2-Naph 113.0-117.0
2-024 3-I i-Pr CF 3 (L-45c) CF 3 107.0-110.0
2-025 3-I CH (CH 3 ) CH 2 SCH 3 CF 3 CF 2 O (Ph-4-Cl) * 1
2-026 3-I CH (CH 3 ) CH 2 SCH 3 CF 3 CH = CH (Ph-4-F) 98.0-111.0
2-027 3-I CH (CH 3 ) CH 2 SCH 3 CF 3 CH = CH (Ph-3-Cl) * 1
2-028 3-I CH (CH 3 ) CH 2 SCH 3 CF 3 CH = CH (Ph-4-Cl) 103.5-108.0
2-029 3-I CH (CH 3 ) CH 2 SCH 3 CF 3 CH = CH (Ph-4-OCF 3 ) * 1
2-030 3-I CH (CH 3 ) CH 2 SCH 3 CF 3 CH = CH (Ph-3,4-Cl 2 ) 98.0-101.0
2-031 3-I CH (CH 3 ) CH 2 SCH 3 CF 3 2-Naph * 1
2-032 3-I CH (CH 3 ) CH 2 SCH 3 CF 3 (L-15b) CF 3 94.0-97.0
2-033 3-I CH (CH 3 ) CH 2 SO 2 CH 3 CF 3 CF 2 O (Ph-4-Cl) 131.5-135.0
2-034 3-I CH (CH 3 ) CH 2 SO 2 CH 3 CF 3 CH = CH (Ph-4-F) 123.0-125.0
2-035 3-I CH (CH 3 ) CH 2 SO 2 CH 3 CF 3 CH = CH (Ph-4-Cl) 128.0-130.5
2-036 3-I CH (CH 3 ) CH 2 SO 2 CH 3 CF 3 CH = CH (Ph-4-OCF 3 ) 120.5-125.0
2-037 3-I CH (CH 3 ) CH 2 SO 2 CH 3 CF 3 CH = CH (Ph-3,4-Cl 2 ) 124.0-128.0
2-038 3-I CH (CH 3 ) CH 2 SO 2 CH 3 CF 3 2-Naph * 1
―――――――――――――――――――――――――――――――――――――――
Table 8

Figure 2005126418
Figure 2005126418

―――――――――――――――――――――――――――――――――――――――
No. (X)m R3 R5 R6 m.p.（℃）
―――――――――――――――――――――――――――――――――――――――
3-001 3-I i-Pr CF2O(Ph-4-Cl) CH3 55.0-65.0
3-002 3-I i-Pr Ph-4-Cl CH3 211.5-214.0
3-003 3-I i-Pr Ph-4-Cl CH2OCH3 226.5-229.0
3-004 3-I i-Pr Ph-4-Cl C(O)CH3 212.0-214.0
3-005 3-I i-Pr CH=CH(Ph-4-Cl) CH3 *1
3-006 3-I CH(CH3)CH2SCH3 CH=CH(Ph-4-Cl) CH3 *1
3-007 3-I CH(CH3)CH2SCH3 CH=CH(Ph-4-Cl) CH2OCH3 *1
3-008 3-I CH(CH3)CH2SCH3 Ph-4-Cl CH3 103.0-107.0
3-009 3-I CH(CH3)CH2SCH3 Ph-4-Cl CH2OCH3 185.0-188.5
3-010 3-I CH(CH3)CH2SCH3 Ph-4-Cl Si(CH3)3 113.0-116.0
3-011 3-I CH(CH3)CH2SCH3 Ph-4-OCH3 Si(CH3)3 99.0-103.0
3-012 3-I CH(CH3)CH2SO2CH3 CH=CH(Ph-4-Cl) CH3 *1
3-013 3-I CH(CH3)CH2SO2CH3 CH=CH(Ph-4-Cl) CH2OCH3 *1
3-014 3-I CH(CH3)CH2SO2CH3 Ph-4-Cl CH3 111.0-114.0
3-015 3-I CH(CH3)CH2SO2CH3 Ph-4-Cl CH2OCH3 *1
3-016 3-I CH(CH3)CH2SO2CH3 Ph-4-OCH3 Si(CH3)3 115.0-119.0
―――――――――――――――――――――――――――――――――――――――
第９表 ―――――――――――――――――――――――――――――――――――――――
No. (X) m R 3 R 5 R 6 mp (℃)
―――――――――――――――――――――――――――――――――――――――
3-001 3-I i-Pr CF 2 O (Ph-4-Cl) CH 3 55.0-65.0
3-002 3-I i-Pr Ph-4-Cl CH 3 211.5-214.0
3-003 3-I i-Pr Ph-4-Cl CH 2 OCH 3 226.5-229.0
3-004 3-I i-Pr Ph-4-Cl C (O) CH 3 212.0-214.0
3-005 3-I i-Pr CH = CH (Ph-4-Cl) CH 3 * 1
3-006 3-I CH (CH 3 ) CH 2 SCH 3 CH = CH (Ph-4-Cl) CH 3 * 1
3-007 3-I CH (CH 3 ) CH 2 SCH 3 CH = CH (Ph-4-Cl) CH 2 OCH 3 * 1
3-008 3-I CH (CH 3 ) CH 2 SCH 3 Ph-4-Cl CH 3 103.0-107.0
3-009 3-I CH (CH 3 ) CH 2 SCH 3 Ph-4-Cl CH 2 OCH 3 185.0-188.5
3-010 3-I CH (CH 3 ) CH 2 SCH 3 Ph-4-Cl Si (CH 3 ) 3 113.0-116.0
3-011 3-I CH (CH 3 ) CH 2 SCH 3 Ph-4-OCH 3 Si (CH 3 ) 3 99.0-103.0
3-012 3-I CH (CH 3 ) CH 2 SO 2 CH 3 CH = CH (Ph-4-Cl) CH 3 * 1
3-013 3-I CH (CH 3 ) CH 2 SO 2 CH 3 CH = CH (Ph-4-Cl) CH 2 OCH 3 * 1
3-014 3-I CH (CH 3 ) CH 2 SO 2 CH 3 Ph-4-Cl CH 3 111.0-114.0
3-015 3-I CH (CH 3 ) CH 2 SO 2 CH 3 Ph-4-Cl CH 2 OCH 3 * 1
3-016 3-I CH (CH 3 ) CH 2 SO 2 CH 3 Ph-4-OCH 3 Si (CH 3 ) 3 115.0-119.0
―――――――――――――――――――――――――――――――――――――――
Table 9

Figure 2005126418
Figure 2005126418

―――――――――――――――――――――――――――――――――――――――
No. (X)m R3 (Y)n R6 m.p.（℃）
―――――――――――――――――――――――――――――――――――――――
4-001 3-I i-Pr 2-CH3 H 123.0-126.0
4-002 3-I i-Pr 6-CH3 H 144.0-146.0
4-003 3-I i-Pr 6-CH3 Ph-4-Cl 195.0-198.0
―――――――――――――――――――――――――――――――――――――――
第１０表 ―――――――――――――――――――――――――――――――――――――――
No. (X) m R 3 (Y) n R 6 mp (℃)
―――――――――――――――――――――――――――――――――――――――
4-001 3-I i-Pr 2-CH 3 H 123.0-126.0
4-002 3-I i-Pr 6-CH 3 H 144.0-146.0
4-003 3-I i-Pr 6-CH 3 Ph-4-Cl 195.0-198.0
―――――――――――――――――――――――――――――――――――――――
Table 10

Figure 2005126418
Figure 2005126418

―――――――――――――――――――――――――――――――――――――――
No. Y1 R4 R5 R6 m.p.（℃）
―――――――――――――――――――――――――――――――――――――――
5-01 CH3 CH3 (L-45c)CF3 H *2
5-02 CH3 CF3 C(O)OEt H *2
5-03 CH3 CF3 CH=CH(Ph-4-F) H 97.0-99.0
5-04 CH3 CF3 Ph-4-Cl H 157.0-160.5
5-05 CH3 CF3 Ph-4-Cl CH3 *2
5-06 CH3 CF3 Ph-4-OCH3 Si(CH3)3 *2
5-07 CH3 CF3 Ph-4-OCF2CHF2 H 69.0-72.0
5-08 CH3 CF3 Ph-4-OCF2CHFOCF3 H 70.0-75.0
5-09 CH3 CF3 Ph-4-OCF2CHFOCF2CF2CF3 H *2
5-10 CH3 CF3 Ph-4-OSO2CH3 H 137.0-139.0
5-11 CH3 CF3 Ph-2,4-Cl2 H 149.0-151.0
5-12 CH3 CF3 Ph-3-CH3-4-OCF2CHFOCF3 H 84.0-87.0
5-13 CH3 CF3 Ph-3-OCF2CF2O-4 H 147.5-150.0
5-14 CH3 CF3 (L-45c)CF3 H 136.0-138.5
―――――――――――――――――――――――――――――――――――――――
［試験例］
次に、本発明化合物の有害生物防除剤としての有用性について、以下の試験例において具体的に説明するが、本発明はこれらのみに限定されるものではない。 ―――――――――――――――――――――――――――――――――――――――
No. Y 1 R 4 R 5 R 6 mp (℃)
―――――――――――――――――――――――――――――――――――――――
5-01 CH 3 CH 3 (L-45c) CF 3 H * 2
5-02 CH 3 CF 3 C (O) OEt H * 2
5-03 CH 3 CF 3 CH = CH (Ph-4-F) H 97.0-99.0
5-04 CH 3 CF 3 Ph-4-Cl H 157.0-160.5
5-05 CH 3 CF 3 Ph-4-Cl CH 3 * 2
5-06 CH 3 CF 3 Ph-4-OCH 3 Si (CH 3 ) 3 * 2
5-07 CH 3 CF 3 Ph-4-OCF 2 CHF 2 H 69.0-72.0
5-08 CH 3 CF 3 Ph-4-OCF 2 CHFOCF 3 H 70.0-75.0
5-09 CH 3 CF 3 Ph-4-OCF 2 CHFOCF 2 CF 2 CF 3 H * 2
5-10 CH 3 CF 3 Ph-4-OSO 2 CH 3 H 137.0-139.0
5-11 CH 3 CF 3 Ph-2,4-Cl 2 H 149.0-151.0
5-12 CH 3 CF 3 Ph-3-CH 3 -4-OCF 2 CHFOCF 3 H 84.0-87.0
5-13 CH 3 CF 3 Ph-3-OCF 2 CF 2 O-4 H 147.5-150.0
5-14 CH 3 CF 3 (L-45c) CF 3 H 136.0-138.5
―――――――――――――――――――――――――――――――――――――――
[Test example]
Next, the usefulness of the compound of the present invention as a pest control agent will be specifically described in the following test examples, but the present invention is not limited to these.

試験例１ コナガに対する殺虫試験
本発明化合物の１０％乳剤（化合物によっては２５％水和剤を供試）を展着剤の入った水で希釈して、100ppm濃度の薬液を調製した。この薬液中にカンランの葉を約１０秒間浸漬し、風乾後シャーレに入れ、この中にコナガ(Plutella xylostella)の２齢幼虫をシャーレ当たり１０頭放虫し、孔の開いた蓋をして２５℃恒温室に収容した。６日後の死虫数を調査し、試験例１と同様の計算式から死虫率を算出した。尚、試験は２区制で行なった。 Test Example 1 Insecticidal test against a diamondback moth A 10% emulsion of the compound of the present invention (for some compounds, 25% wettable powder) was diluted with water containing a spreading agent to prepare a chemical solution having a concentration of 100 ppm. Immerse kanran leaves in this solution for about 10 seconds, air-dry and place in a petri dish. 10 second-instar larvae of Plutella xylostella are released per petri dish and covered with a hole. Housed in a constant temperature room. The number of dead insects after 6 days was investigated, and the death rate was calculated from the same calculation formula as in Test Example 1. The test was conducted in a two-ward system.

その結果、下記の化合物が１００％の死虫率を示した。
本発明化合物：No.1-001,1-002,1-003,1-004,1-005,1-006,1-007,1-008,1-009,1-010,1-011,1-012,1-013,1-014,1-015,1-016,1-017,1-018,1-019,1-020,1-021,1-022,1-023,1-024,1-025,1-026,1-027,1-028,1-029,1-030,1-031,1-032,1-033,1-034,1-035,1-036,1-037,1-038,1-039,1-040,1-041,1-042,1-043,1-044,1-045,1-046,1-047,1-048,1-050,1-051,1-052,1-053,1-054,1-055,1-056,1-057,1-058,1-059,1-060,1-061,1-062,1-063,1-064,1-065,1-066,1-067,1-068,1-069,1-070,1-071,1-072,1-073,1-074,1-075,1-076,1-077,1-078,1-079,1-080,1-081,1-082,1-083,1-084,1-085,1-086,1-087,1-088,1-089,1-090,2-001,2-002,2-003,2-004,2-005,2-006,2-007,2-008,2-009,2-010,2-011,2-012,2-013,2-014,2-015,2-016,2-017,2-018,2-019,2-020,2-021,2-022,2-023,2-024,2-025,2-026,2-027,2-028,2-029,2-030,2-031,2-032,2-033,2-034,2-035,2-036,2-037,2-038,3-001,3-002,3-004,3-005,3-006,3-007,3-008,3-009,3-010,3-011,3-012,3-013,3-014,3-015,4-001,4-002。 As a result, the following compounds showed 100% mortality.
Compound of the present invention: No.1-001,1-002,1-003,1-004,1-005,1-006,1-007,1-008,1-009,1-010,1-011, 1-012,1-013,1-014,1-015,1-016,1-017,1-018,1-019,1-020,1-021,1-022,1-023,1- 024,1-025,1-026,1-027,1-028,1-029,1-030,1-031,1-032,1-033,1-034,1-035,1-036, 1-037,1-038,1-039,1-040,1-041,1-042,1-043,1-044,1-045,1-046,1-047,1-048,1- 050,1-051,1-052,1-053,1-054,1-055,1-056,1-057,1-058,1-059,1-060,1-061,1-062, 1-063,1-064,1-065,1-066,1-067,1-068,1-069,1-070,1-071,1-072,1-073,1-074,1- 075,1-076,1-077,1-078,1-079,1-080,1-081,1-082,1-083,1-084,1-085,1-086,1-087, 1-088,1-089,1-090,2-001,2-002,2-003,2-004,2-005,2-006,2-007,2-008,2-009,2- 010,2-011,2-012,2-013,2-014,2-015,2-016,2-017,2-018,2-019,2-020,2-021,2-022, 2-023, 2-024, 2-025, 2-026, 2-027, 2-028, 2-029, 2-030, 2-031, 2-032, 2-033, 2-034, 2- 035,2-036,2-037,2-038,3-001,3-002,3-004,3-005,3-006,3-007,3-008,3-009,3-010, 3-011, 3-012, 3-013, 3-014, 3-015, 4-001, 4-002.

試験例２ ハスモンヨトウに対する殺虫試験
本発明化合物の１０％乳剤（化合物によっては２５％水和剤を供試）を展着剤の入った水で希釈して、100ppm濃度の薬液を調製した。この薬液中にカンランの葉を約１０秒間浸漬し、風乾後シャーレに入れ、この中にハスモンヨトウ(Spodoptera litura)の２齢幼虫をシャーレ当たり１０頭放虫し、孔の開いた蓋をして２５℃恒温室に収容した。６日後の死虫数を調査し、下記の計算式から死虫率を算出した。尚、試験は２区制で行なった。 Test Example 2 Insecticidal test against Spodoptera litura 10% emulsion of the compound of the present invention (depending on the compound, 25% wettable powder was tested) was diluted with water containing a spreading agent to prepare a chemical solution having a concentration of 100 ppm. Immerse kanran leaves in this chemical for about 10 seconds, air dry and place in a petri dish. 10 second-instar larvae of Spodoptera litura are released per petri dish, and a lid with a hole is opened. Housed in a constant temperature room. The number of dead insects after 6 days was investigated, and the death rate was calculated from the following formula. The test was conducted in a two-ward system.

死虫率（％）＝（死虫数／放虫数）×１００
その結果、下記の化合物が８０％以上の死虫率を示した。
本発明化合物：No.1-001,1-003,1-005,1-006,1-007,1-009,1-010,1-011,1-012,1-013,1-014,1-015,1-016,1-017,1-020,1-021,1-022,1-023,1-024,1-025,1-026,1-027,1-028,1-029,1-031,1-032,1-034,1-035,1-036,1-038,1-040,1-041,1-042,1-043,1-044,1-045,1-047,1-048,1-050,1-051,1-052,1-053,1-054,1-055,1-056,1-057,1-058,1-059,1-063,1-065,1-066,1-067,1-069,1-070,1-071,1-072,1-073,1-074,1-075,1-076,1-077,1-078,1-079,1-080,1-081,1-082,1-083,1-084,1-085,1-086,1-087,1-088,1-089,1-090,2-001,2-004,2-007,2-008,2-012,2-016,2-017,2-018,2-019,2-020,2-022,2-024,2-025,2-026,2-027,2-028,2-029,2-030,2-033,2-034,2-035,2-036,2-037,3-001,3-002,3-004,3-005,3-006,3-007,3-008,3-009,3-010,3-012,3-013,3-014,3-015,4-001,4-002。 Death rate (%) = (Number of dead insects / Number of dead insects) × 100
As a result, the following compounds showed a death rate of 80% or more.
Compound of the present invention: No.1-001,1-003,1-005,1-006,1-007,1-009,1-010,1-011,1-012,1-013,1-014, 1-015,1-016,1-017,1-020,1-021,1-022,1-023,1-024,1-025,1-026,1-027,1-028,1- 029,1-031,1-032,1-034,1-035,1-036,1-038,1-040,1-041,1-042,1-043,1-044,1-045, 1-047,1-048,1-050,1-051,1-052,1-053,1-054,1-055,1-056,1-057,1-058,1-059,1- 063,1-065,1-066,1-067,1-069,1-070,1-071,1-072,1-073,1-074,1-075,1-076,1-077, 1-078,1-079,1-080,1-081,1-082,1-083,1-084,1-085,1-086,1-087,1-088,1-089,1- 090,2-001,2-004,2-007,2-008,2-012,2-016,2-017,2-018,2-019,2-020,2-022,2-024, 2-025, 2-026, 2-027, 2-028, 2-029, 2-030, 2-033, 2-034, 2-035, 2-036, 2-037, 3-001, 3- 002,3-004,3-005,3-006,3-007,3-008,3-009,3-010,3-012,3-013,3-014,3-015,4-001, 4-002.

試験例３ チャハマキに対する殺虫試験
本発明化合物の１０％乳剤（化合物によっては１０％水和剤を供試）を展着剤の入った水で希釈して、100ppm濃度の薬液を調製した。この薬液中にカンランの葉を約１０秒間浸漬し、風乾後シャーレに入れ、この中にチャハマキ(Homona magnanima)の２齢幼虫をシャーレ当たり５頭放虫し、蓋をして２５℃恒温室に収容した。６日後の死虫数を調査し、試験例１と同様の計算式から死虫率を算出した。尚、試験は２連制で行なった。 Test Example 3 Insecticidal Test for Chahamaki A 10% emulsion of the compound of the present invention (10% wettable powder was tested depending on the compound) was diluted with water containing a spreading agent to prepare a chemical solution having a concentration of 100 ppm. Soak kanran leaves in this chemical solution for about 10 seconds, air dry and place in a petri dish. In this, 5 second-instar larvae of Homona magnanima are released per petri dish, covered and placed in a constant temperature room at 25 ° C. Accommodated. The number of dead insects after 6 days was investigated, and the death rate was calculated from the same calculation formula as in Test Example 1. In addition, the test was performed by 2 continuous systems.

その結果、下記の化合物が８０％以上の死虫率を示した。
本発明化合物：No.1-001,1-003,1-004,1-005,1-006,1-007,1-009,1-010,1-011,1-012,1-013,1-017,1-020,1-021,1-022,1-023,1-024,1-025,1-026,1-027,1-028,1-032,1-034,1-035,1-036,1-038,1-040,1-041,1-042,1-043,1-044,1-045,1-048,1-050,1-051,1-052,1-053,1-054,1-056,1-057,1-058,1-059,1-062,1-063,1-065,1-066,1-067,1-069,1-070,1-071,1-072,1-073,1-075,1-076,1-077,1-078,1-079,1-081,1-082,1-083,1-084,1-085,1-086,1-088,1-089,2-008,2-016,2-018,2-019,2-024,2-029,2-033,2-035,3-001,3-002,3-008,3-009,3-014,3-015,4-001,4-002。 As a result, the following compounds showed a death rate of 80% or more.
Compound of the present invention: No.1-001,1-003,1-004,1-005,1-006,1-007,1-009,1-010,1-011,1-012,1-013, 1-017,1-020,1-021,1-022,1-023,1-024,1-025,1-026,1-027,1-028,1-032,1-034,1- 035,1-036,1-038,1-040,1-041,1-042,1-043,1-044,1-045,1-048,1-050,1-051,1-052, 1-053,1-054,1-056,1-057,1-058,1-059,1-062,1-063,1-065,1-066,1-067,1-069,1- 070,1-071,1-072,1-073,1-075,1-076,1-077,1-078,1-079,1-081,1-082,1-083,1-084, 1-085,1-086,1-088,1-089,2-008,2-016,2-018,2-019,2-024,2-029,2-033,2-035,3- 001,3-002,3-008,3-009,3-014,3-015,4-001,4-002.

試験例４ ウリハムシに対する殺虫試験
本発明化合物の１０％乳剤（化合物によっては１０％水和剤を供試）を展着剤の入った水で希釈して、500ppm濃度の薬液を調製した。この薬液中にキュウリの葉を約１０秒間浸漬し、風乾後シャーレに入れ、この中にウリハムシ(Aulacophora femoralis)の２齢幼虫をシャーレ当たり５頭放虫し、蓋をして２５℃恒温室に収容した。６日後の死虫数を調査し、試験例１と同様の計算式から死虫率を算出した。尚、試験は２連制で行なった。 Test Example 4 Insecticidal test against cucumber potato beetle A 10% emulsion of the compound of the present invention (10% wettable powder depending on the compound) was diluted with water containing a spreading agent to prepare a chemical solution having a concentration of 500 ppm. Soak cucumber leaves in this chemical solution for about 10 seconds, air-dry and place in a petri dish. 5 second-instar larvae of Aulacophora femoralis are released per petri dish, covered and placed in a constant temperature room at 25 ° C. Accommodated. The number of dead insects after 6 days was investigated, and the death rate was calculated from the same calculation formula as in Test Example 1. In addition, the test was performed by 2 continuous systems.

その結果、下記の化合物が１００％の死虫率を示した。
本発明化合物：No.1-001,1-004,1-005,1-006,1-007,1-009,1-010,1-011,1-012,1-013,1-014,1-016,1-017,1-018,1-020,1-022,1-023,1-024,1-025,1-026,1-027,1-028,1-031,1-032,1-035,1-036,1-038,1-040,1-041,1-042,1-043,1-044,1-045,1-047,1-048,1-050,1-052,1-053,1-054,1-055,1-056,1-057,1-058,1-059,1-062,1-063,1-064,1-066,1-067,1-068,1-069,1-070,1-071,1-072,1-073,1-074,1-075,1-077,1-078,1-079,1-080,1-081,1-082,1-083,1-084,1-085,1-086,1-087,1-088,1-089,2-001,2-004,2-008,2-009,2-010,2-016,2-017,2-018,2-019,2-021,2-022,2-024,2-025,2-026,2-028,2-029,2-030,2-033,2-034,2-035,2-036,2-037,3-001,3-005,3-006,3-007,3-008,3-010,3-012,3-013,3-014,4-001,4-002。 As a result, the following compounds showed 100% mortality.
Compound of the present invention: No.1-001,1-004,1-005,1-006,1-007,1-009,1-010,1-011,1-012,1-013,1-014, 1-016,1-017,1-018,1-020,1-022,1-023,1-024,1-025,1-026,1-027,1-028,1-031,1- 032,1-035,1-036,1-038,1-040,1-041,1-042,1-043,1-044,1-045,1-047,1-048,1-050, 1-052,1-053,1-054,1-055,1-056,1-057,1-058,1-059,1-062,1-063,1-064,1-066,1- 067,1-068,1-069,1-070,1-071,1-072,1-073,1-074,1-075,1-077,1-078,1-079,1-080, 1-081,1-082,1-083,1-084,1-085,1-086,1-087,1-088,1-089,2-001,2-004,2-008,2- 009,2-010,2-016,2-017,2-018,2-019,2-021,2-022,2-024,2-025,2-026,2-028,2-029, 2-030,2-033,2-034,2-035,2-036,2-037,3-001,3-005,3-006,3-007,3-008,3-010,3- 012,3-013,3-014,4-001,4-002.

試験例５ ハスモンヨトウに対する殺虫試験（比較試験）
本発明化合物及び比較化合物の１０％乳剤を展着剤の入った水で希釈して、所定濃度の薬液を調製した。この薬液中にカンランの葉を約１０秒間浸漬し、風乾後シャーレに入れ、この中にハスモンヨトウ(Spodoptera litura)の３齢幼虫をシャーレ当たり７頭放虫し、孔の開いた蓋をして２５℃恒温室に収容した。処理２日後に人工飼料（１ｃｍ３）を加え、６日後の死虫数を調査し、下記の計算式から死虫率を算出した。尚、試験は２区制で行なった。 Test Example 5 Insecticidal test against Spodoptera litura (Comparative test)
A 10% emulsion of the compound of the present invention and the comparative compound was diluted with water containing a spreading agent to prepare a chemical solution having a predetermined concentration. Immerse kanran leaves in this chemical for about 10 seconds, air-dry and place in a petri dish. In this, 7 third-instar larvae of Spodoptera litura are released per petri dish, and a lid with a hole is opened. Housed in a constant temperature room. Artificial feed (1 cm 3 ) was added 2 days after the treatment, the number of dead insects after 6 days was investigated, and the death rate was calculated from the following formula. The test was conducted in a two-ward system.

死虫率（％）＝（死虫数／放虫数）×１００
各供試化合物の各所定濃度における死虫率を第１１表に示す。
第１１表
――――――――――――――――――――――――――――――――――――
供試化合物 濃度（ppm）
33 10 3 1 0.3 0.1
――――――――――――――――――――――――――――――――――――
本発明化合物 No.1-036 100 100 100 85.7 28.6 14.3
本発明化合物 No.1-084 100 100 71.4 21.3 0
本発明化合物 No.1-087 100 100 100 71.4 21.3 0
比較化合物 A 0
――――――――――――――――――――――――――――――――――――
比較化合物 A：欧州特許出願公開第１００６１０７号明細書、化合物No.472 Death rate (%) = (Number of dead insects / Number of dead insects) × 100
Table 11 shows the death rate of each test compound at each predetermined concentration.
Table 11 ――――――――――――――――――――――――――――――――――――
Test compound concentration (ppm)
33 10 3 1 0.3 0.1
――――――――――――――――――――――――――――――――――――
Compound of the present invention No.1-036 100 100 100 85.7 28.6 14.3
Compound of the present invention No.1-084 100 100 71.4 21.3 0
Compound No.1-087 100 100 100 71.4 21.3 0
Comparative compound A 0
――――――――――――――――――――――――――――――――――――
Comparative compound A: European Patent Application No. 1006107, Compound No. 472

Figure 2005126418
Figure 2005126418

本発明に係る置換ベンズアニリド化合物は、優れた有害生物防除活性、特に殺虫・殺ダニ活性を示し、且つ、ホ乳動物、魚類及び益虫等の非標的生物に対してほとんど悪影響の無い、極めて有用な化合物である。
The substituted benzanilide compound according to the present invention exhibits excellent pest control activity, particularly insecticidal / miticidal activity, and is extremely useful with little adverse effect on non-target organisms such as mammals, fish and beneficial insects. A compound.

Claims (8)

一般式（１）：
Figure 2005126418
 ［式中、W1及びW2は、各々独立して酸素原子又は硫黄原子を表し、
Xは、ハロゲン原子、シアノ、ニトロ、アジド、-SCN、-SF5、C1〜C6アルキル、R7によって任意に置換された(C1〜C6)アルキル、C3〜C8シクロアルキル、R7によって任意に置換された(C3〜C8)シクロアルキル、C2〜C6アルケニル、R7によって任意に置換された(C2〜C6)アルケニル、C3〜C8シクロアルケニル、C3〜C8ハロシクロアルケニル、C2〜C6アルキニル、R7によって任意に置換された(C2〜C6)アルキニル、-OH、-OR8、-OS(O)2R8、-SH、-S(O)rR8、-CHO、-C(O)R9、-C(O)OR9、-C(O)SR9、-C(O)NHR10、-C(O)N(R10)R9、-C(S)OR9、-C(S)SR9、-C(S)NHR10、-C(S)N(R10)R9、-CH=NOR11、-C(R9)=NOR11、-S(O)2OR9、-S(O)2NHR10、-S(O)2N(R10)R9、-Si(R13)(R14)R12、フェニル、(Z)p1によって置換されたフェニル、L又はMを表し、mが２、３又は４を表すとき、各々のXは互いに同一であっても又は互いに相異なっていてもよく、
さらに、２つのXが隣接する場合には、隣接する２つのXは-CH2CH2CH2-, -CH2CH2O-, -CH2OCH2-, -OCH2O-, -CH2CH2S-, -CH2SCH2-, -CH2CH2N(R15)-, -CH2N(R15)CH2-, -CH2CH2CH2CH2-, -CH2CH2CH2O-, -CH2CH2OCH2-, -CH2OCH2O-, -OCH2CH2O-, -OCH2CH2S-, -CH2CH=CH-, -OCH=CH-, -SCH=CH-, -N(R15)CH=CH-, -OCH=N-, -SCH=N-, -N(R15)CH=N-, -N(R15)N=CH-, -CH=CHCH=CH-, -OCH2CH=CH-, -N=CHCH=CH-, -N=CHCH=N-又は-N=CHN=CH-を形成することにより、２つのXのそれぞれが結合する炭素原子と共に５員環又は６員環を形成してもよく、このとき、環を形成する各々の炭素原子に結合した水素原子はZによって任意に置換されていてもよく、さらに、同時に２個以上のZで置換されている場合、各々のZは互いに同一であっても又は互いに相異なっていてもよく、
Yは、ハロゲン原子、シアノ、ニトロ、C1〜C6アルキル、R7によって任意に置換された(C1〜C6)アルキル、C3〜C8シクロアルキル、-OR8、-S(O)rR8、-NH2、C1〜C6アルキルアミノ、ジ(C1〜C6アルキル)アミノ又は-Si(R13)(R14)R12を表し、nが２、３又は４を表すとき、各々のYは互いに同一であっても又は互いに相異なっていてもよく、
さらに、２つのYが隣接する場合には、隣接する２つのYは-CH2CH2CH2-, -CH2CH2O-, -CH2OCH2-, -OCH2O-, -CH2CH2S-, -CH2SCH2-, -SCH2S-, -CH2CH2CH2CH2-, -CH2CH2CH2O-, -CH2CH2OCH2-, -CH2OCH2O-, -OCH2CH2O-, -OCH2CH2S-, -SCH2CH2S-, -OCH=N-又は-SCH=N-を形成することにより、２つのYのそれぞれが結合する炭素原子と共に５員環又は６員環を形成してもよく、このとき、環を形成する各々の炭素原子に結合した水素原子はZによって任意に置換されていてもよく、さらに、同時に２個以上のZで置換されている場合、各々のZは互いに同一であっても又は互いに相異なっていてもよく、
R1は、水素原子、シアノ、C1〜C12アルキル、R16によって任意に置換された(C1〜C12)アルキル、C3〜C12シクロアルキル、R16によって任意に置換された(C3〜C12)シクロアルキル、C3〜C12アルケニル、R16によって任意に置換された(C3〜C12)アルケニル、C3〜C12シクロアルケニル、C3〜C12ハロシクロアルケニル、C3〜C12アルキニル、R16によって任意に置換された(C3〜C12)アルキニル、-OH、C1〜C8アルコキシ、C3〜C8アルケニルオキシ、C3〜C8ハロアルケニルオキシ、フェノキシ、(Z)p1によって置換されたフェノキシ、フェニル(C1〜C4)アルコキシ、(Z)p1によって置換されたフェニル(C1〜C4)アルコキシ、-N(R20)R19、フェニル、(Z)p1によって置換されたフェニル、L又はMを表し、
R2及びR3は、各々独立して水素原子、シアノ、C1〜C12アルキル、R16によって任意に置換された(C1〜C12)アルキル、C3〜C12アルケニル、C3〜C12ハロアルケニル、C3〜C12アルキニル、C3〜C12ハロアルキニル、-OH、C1〜C8アルコキシ、C1〜C6アルキルチオ、C1〜C6ハロアルキルチオ、フェニルチオ、(Z)p1によって置換されたフェニルチオ、-S(O)2R9、-SN(R18)R17、-S(O)2N(R10)R9、-N(R20)R19、-C(O)R9、-C(O)OR9、-C(O)SR9、-C(O)N(R10)R9、-C(S)OR9、-C(S)SR9、-C(S)N(R10)R9、フェニル又は(Z)p1によって置換されたフェニルを表すか、或いは、R2はR1と一緒になってC2〜C6アルキレン鎖を形成することにより、結合する窒素原子と共に３〜７員環を形成してもよいことを表し、このときこのアルキレン鎖は酸素原子、硫黄原子又は窒素原子を１個含んでもよく、且つハロゲン原子、C1〜C6アルキル基、C1〜C6ハロアルキル基、C1〜C6アルコキシ基、C1〜C6アルキルカルボニル基又はC1〜C6アルコキシカルボニル基によって任意に置換されていてもよく、
R4は、C1〜C6アルキル、C1〜C6ハロアルキル、R21によって任意に置換された(C1〜C6)アルキル、R21によって任意に置換された(C1〜C6)ハロアルキル、C3〜C8シクロアルキル、C3〜C8ハロシクロアルキル、R21によって任意に置換された(C3〜C8)シクロアルキル、R21によって任意に置換された(C3〜C8)ハロシクロアルキル、C3〜C6アルケニル、C3〜C6ハロアルケニル、C3〜C6アルキニル、C3〜C6ハロアルキニル、フェニル、(Z)p1によって置換されたフェニル、L又はMを表し、
R5は、シアノ、R21によって任意に置換された(C1〜C6)アルキル、R21によって任意に置換された(C1〜C6)ハロアルキル、R21によって任意に置換された(C3〜C8)シクロアルキル、R21によって任意に置換された(C3〜C8)ハロシクロアルキル、R21によって任意に置換された(C2〜C6)アルケニル、C3〜C8シクロアルケニル、C3〜C8ハロシクロアルケニル、R21によって任意に置換された(C2〜C6)アルキニル、-OR8、-S(O)rR8、-N(R10)R9、-CHO、-C(O)R9、-CH=NOR11、-C(R9)=NOR11、-C(O)OR9、-C(O)SR9、-C(O)NHR10、-C(O)N(R10)R9、-C(S)OR9、-C(S)SR9、-C(S)NHR10、-C(S)N(R10)R9、フェニル、(Z)p1によって置換されたフェニル、ビフェニル、(Z)p1によって置換されたビフェニル、フェノキシフェニル、(Z)p1によって置換されたフェノキシフェニル、ピリジルオキシフェニル、(Z)p1によって置換されたピリジルオキシフェニル、フェニルチオフェニル、(Z)p1によって置換されたフェニルチオフェニル、フェニルスルフィニルフェニル、(Z)p1によって置換されたフェニルスルフィニルフェニル、フェニルスルホニルフェニル、(Z)p1によって置換されたフェニルスルホニルフェニル、L又はMを表すか、或いは、隣接位に存在するYと一緒になってC2〜C3アルキレン鎖を形成することにより、ベンゼン環と縮合する５〜６員環を形成してもよいことを表し、このときこのアルキレン鎖は酸素原子、硫黄原子又は窒素原子を１個含んでもよく、且つハロゲン原子又はC1〜C6ハロアルキル基によって任意に置換されていてもよく、
R6は、水素原子、C1〜C6アルキル、C1〜C6ハロアルキル、R21によって任意に置換された(C1〜C6)アルキル、R21によって任意に置換された(C1〜C6)ハロアルキル、C3〜C8シクロアルキル、C3〜C6アルケニル、C3〜C6ハロアルケニル、フェニル(C3〜C6)アルケニル、(Z)p1によって置換されたフェニル(C3〜C6)アルケニル、C3〜C8シクロアルケニル、C3〜C6アルキニル、C3〜C6ハロアルキニル、フェニル(C3〜C6)アルキニル、(Z)p1によって置換されたフェニル(C3〜C6)アルキニル、-S(O)2R9、-C(O)R9、-C(O)OR9、-C(O)SR9、-C(S)OR9、-C(S)SR9、-C(O)NHR10、-C(O)N(R10)R9、-C(S)NHR10、-C(S)N(R10)R9、-Si(R13)(R14)R12、-P(O)(OR22)2、-P(S)(OR22)2又はMを表し、
Lは、式L-1から式L-58までの何れかで表される芳香族複素環を表し、
Figure 2005126418
Figure 2005126418
 Mは、式M-1から式M-28までの何れかで表される飽和複素環を表し、
Figure 2005126418
 Zは、ハロゲン原子、シアノ、ニトロ、アジド、-SCN、-SF5、C1〜C6アルキル、C1〜C6ハロアルキル、C1〜C3アルコキシ(C1〜C3)アルキル、C1〜C3ハロアルコキシ(C1〜C3)アルキル、シアノ(C1〜C6)アルキル、ヒドロキシ(C1〜C3)ハロアルキル、C1〜C3アルコキシ(C1〜C3)ハロアルキル、C1〜C3ハロアルコキシ(C1〜C3)ハロアルキル、C1〜C3アルキルチオ(C1〜C3)アルキル、C1〜C3ハロアルキルチオ(C1〜C3)アルキル、C1〜C3アルキルスルフィニル(C1〜C3)アルキル、C1〜C3ハロアルキルスルフィニル(C1〜C3)アルキル、C1〜C3アルキルスルホニル(C1〜C3)アルキル、C1〜C3ハロアルキルスルホニル(C1〜C3)アルキル、C3〜C8シクロアルキル、C3〜C8ハロシクロアルキル、C2〜C6アルケニル、C2〜C6ハロアルケニル、C3〜C8シクロアルケニル、C3〜C8ハロシクロアルケニル、C2〜C6アルキニル、C2〜C6ハロアルキニル、-OH、C1〜C6アルコキシ、C1〜C6ハロアルコキシ、C1〜C3ハロアルコキシ(C1〜C3)ハロアルコキシ、C2〜C6アルケニルオキシ、C2〜C6ハロアルケニルオキシ、C3〜C6アルキニルオキシ、C3〜C6ハロアルキニルオキシ、C1〜C6アルキルスルホニルオキシ、C1〜C6ハロアルキルスルホニルオキシ、-SH、C1〜C6アルキルチオ、C1〜C6ハロアルキルチオ、C1〜C6アルキルスルフィニル、C1〜C6ハロアルキルスルフィニル、C1〜C6アルキルスルホニル、C1〜C6ハロアルキルスルホニル、-NH2、C1〜C6アルキルアミノ、ジ(C1〜C6アルキル)アミノ、C1〜C6アルキルスルホニルアミノ、C1〜C6ハロアルキルスルホニルアミノ、C1〜C6アルコキシカルボニル、C1〜C6ハロアルコキシカルボニル、-C(O)NH2、C1〜C6アルキルアミノカルボニル、ジ(C1〜C6アルキル)アミノカルボニル、-C(S)NH2、C1〜C6アルキルアミノスルホニル、ジ(C1〜C6アルキル)アミノスルホニル又はトリ(C1〜C6アルキル)シリルを表し、p1, p2, p3又はp4が２以上の整数を表すとき、各々のZは互いに同一であっても又は互いに相異なっていてもよく、
さらに、２つのZが隣接する場合には、隣接する２つのZは-CH2CH2CH2-, -CH2CH2O-, -CH2OCH2-, -OCH2O-, -CH2CH2S-, -CH2SCH2-, -CH2CH2CH2CH2-, -CH2CH2CH2O-, -CH2CH2OCH2-, -CH2OCH2O-, -OCH2CH2O-, -OCH2CH2S-又は-CH=CHCH=CH-を形成することにより、２つのZのそれぞれが結合する炭素原子と共に５員環又は６員環を形成してもよく、このとき、環を形成する各々の炭素原子に結合した水素原子はハロゲン原子又はC1〜C6アルキル基によって任意に置換されていてもよく、
R7は、ハロゲン原子、シアノ、C3〜C8シクロアルキル、C3〜C8ハロシクロアルキル、-OH、-OR8、-SH、-S(O)rR8、-N(R10)R9、-N(R10)CHO、-N(R10)C(O)R9、-N(R10)C(O)OR9、-N(R10)C(O)SR9、-N(R10)C(S)OR9、-N(R10)C(S)SR9、-N(R10)S(O)2R9、-C(O)OR9、-C(O)N(R10)R9、-Si(R13)(R14)R12、フェニル、(Z)p1によって置換されたフェニル、L又はMを表し、
R8は、C1〜C6アルキル、R25によって任意に置換された(C1〜C6)アルキル、C3〜C8シクロアルキル、R25によって任意に置換された(C3〜C8)シクロアルキル、C2〜C6アルケニル、R25によって任意に置換された(C2〜C6)アルケニル、C3〜C8シクロアルケニル、C3〜C8ハロシクロアルケニル、C3〜C6アルキニル、R25によって任意に置換された(C3〜C6)アルキニル、フェニル、(Z)p1によって置換されたフェニル、L又はMを表し、
R9は、C1〜C6アルキル、C1〜C6ハロアルキル、C3〜C6シクロアルキル(C1〜C4)アルキル、C1〜C6アルコキシ(C1〜C4)アルキル、C1〜C6アルキルチオ(C1〜C4)アルキル、シアノ(C1〜C6)アルキル、フェニル(C1〜C4)アルキル、(Z)p1によって置換されたフェニル(C1〜C4)アルキル、L-(C1〜C4)アルキル、M-(C1〜C4)アルキル、C3〜C8シクロアルキル、C3〜C8ハロシクロアルキル、C3〜C6アルケニル、C3〜C6ハロアルケニル、C3〜C6アルキニル、フェニル又は(Z)p1によって置換されたフェニルを表し、
R10は、水素原子又はC1〜C6アルキルを表すか、或いは、R9とR10とが一緒になってC2〜C6アルキレン鎖を形成することにより、結合する原子と共に３〜７員環を形成してもよいことを表し、このときこのアルキレン鎖は酸素原子、硫黄原子又は窒素原子を１個含んでもよく、且つハロゲン原子、C1〜C6アルキル基、C1〜C6アルコキシ基、ホルミル基、C1〜C6アルキルカルボニル基又はC1〜C6アルコキシカルボニル基によって任意に置換されていてもよく、
R11は、水素原子、C1〜C6アルキル、C1〜C6ハロアルキル、フェニル(C1〜C4)アルキル、(Z)p1によって置換されたフェニル(C1〜C4)アルキル、C3〜C6アルケニル、C3〜C6ハロアルケニル、C3〜C6アルキニル又はC3〜C6ハロアルキニルを表すか、或いは、R11はR9と一緒になってC2〜C4アルキレン鎖を形成することにより、結合する原子と共に５〜７員環を形成してもよいことを表し、このときこのアルキレン鎖は酸素原子、硫黄原子又は窒素原子を１個含んでもよく、且つハロゲン原子又はC1〜C6アルキル基によって任意に置換されていてもよく、
R12は、C1〜C6アルキル、C1〜C6ハロアルキル、C3〜C6アルケニル、フェニル又は(Z)p1によって置換されたフェニルを表し、
R13及びR14は、各々独立してC1〜C6アルキル又はC1〜C6ハロアルキルを表し、
R15は、水素原子、C1〜C6アルキル、C1〜C6ハロアルキル、C1〜C6アルコキシカルボニル(C1〜C4)アルキル、C1〜C6ハロアルコキシカルボニル(C1〜C4)アルキル、フェニル(C1〜C4)アルキル、(Z)p1によって置換されたフェニル(C1〜C4)アルキル、C3〜C6アルケニル、C3〜C6ハロアルケニル、C3〜C6アルキニル、C3〜C6ハロアルキニル、C1〜C6アルコキシ、C1〜C6アルコキシカルボニル、C1〜C6ハロアルコキシカルボニル、フェニル又は(Z)p1によって置換されたフェニルを表し、
R16は、ハロゲン原子、シアノ、ニトロ、C3〜C8シクロアルキル、C3〜C8ハロシクロアルキル、-OR26、-N(R27)R26、-SH、-S(O)rR28、-SO2NHR30、-SO2N(R30)R29、-CHO、-C(O)R29、-C(O)OH、-C(O)OR29、-C(O)SR29、-C(O)NHR30、-C(O)N(R30)R29、-C(O)C(O)OR29、-C(R32)=NOH、-C(R32)=NOR31、-Si(R13)(R14)R12、-P(O)(OR22)2、-P(S)(OR22)2、-P(フェニル)2、-P(O)(フェニル)2、フェニル、(Z)p1によって置換されたフェニル、L又はMを表し、
R17は、C1〜C12アルキル、C1〜C12ハロアルキル、C1〜C12アルコキシ(C1〜C12)アルキル、シアノ(C1〜C12)アルキル、C1〜C12アルコキシカルボニル(C1〜C12)アルキル、フェニル(C1〜C4)アルキル、(Z)p1によって置換されたフェニル(C1〜C4)アルキル、C3〜C12アルケニル、C3〜C12ハロアルケニル、C3〜C12アルキニル、C3〜C12ハロアルキニル、C1〜C12アルキルカルボニル、C1〜C12アルコキシカルボニル、フェニル又は(Z)p1によって置換されたフェニルを表し、
R18は、C1〜C12アルキル、C1〜C12ハロアルキル、C1〜C12アルコキシ(C1〜C12)アルキル、シアノ(C1〜C12)アルキル、C1〜C12アルコキシカルボニル(C1〜C12)アルキル、フェニル(C1〜C4)アルキル、(Z)p1によって置換されたフェニル(C1〜C4)アルキル、C3〜C12アルケニル、C3〜C12ハロアルケニル、C3〜C12アルキニル、C3〜C12ハロアルキニル、フェニル又は(Z)p1によって置換されたフェニルを表すか、或いは、R17とR18とが一緒になってC4〜C7アルキレン鎖を形成することにより、結合する窒素原子と共に５〜８員環を形成してもよいことを表し、このときこのアルキレン鎖は酸素原子又は硫黄原子を１個含んでもよく、且つC1〜C4アルキル基又はC1〜C4アルコキシ基によって任意に置換されていてもよく、
R19は、水素原子、C1〜C6アルキル、C1〜C6ハロアルキル、フェニル(C1〜C4)アルキル、(Z)p1によって置換されたフェニル(C1〜C4)アルキル、C3〜C6アルケニル、C3〜C6ハロアルケニル、C3〜C6アルキニル、-CHO、C1〜C6アルキルカルボニル、C1〜C6ハロアルキルカルボニル、C1〜C6アルコキシカルボニル、C1〜C6ハロアルコキシカルボニル、フェニル(C1〜C4)アルコキシカルボニル、(Z)p1によって置換されたフェニル(C1〜C4)アルコキシカルボニル、フェノキシカルボニル、(Z)p1によって置換されたフェノキシカルボニル、フェニルカルボニル、(Z)p1によって置換されたフェニルカルボニル、フェニル又は(Z)p1によって置換されたフェニルを表し、
R20は、水素原子、C1〜C6アルキル、-CHO、C1〜C6アルキルカルボニル、C1〜C6ハロアルキルカルボニル又はC1〜C6アルコキシカルボニルを表し、
R21は、シアノ、C3〜C8シクロアルキル、C3〜C8ハロシクロアルキル、-OH、-OR8、-SH、-S(O)rR8、-N(R10)R9、-N(R10)CHO、-N(R10)C(O)R9、-N(R10)C(O)OR9、-N(R10)C(O)SR9、-N(R10)C(S)OR9、-N(R10)C(S)SR9、-N(R10)S(O)2R9、-C(O)OR9、-C(O)N(R10)R9、-Si(R13)(R14)R12、フェニル、(Z)p1によって置換されたフェニル、L又はMを表し、
R22は、C1〜C6アルキル又はC1〜C6ハロアルキルを表し、
R23は、ハロゲン原子、シアノ、C1〜C6アルキル、C1〜C6ハロアルキル、ヒドロキシ(C1〜C6)アルキル、C1〜C4アルコキシ(C1〜C4)アルキル、C1〜C4アルコキシカルボニル(C1〜C4)アルキル、C1〜C6アルコキシ、C1〜C6アルコキシカルボニル、フェニル又は(Z)p1によって置換されたフェニルを表し、q1, q2, q3又はq4が２以上の整数を表すとき、各々のR23は互いに同一であっても、または互いに相異なっていてもよく、
R24は、水素原子、C1〜C6アルキル、C1〜C6ハロアルキル、-CHO、C1〜C6アルキルカルボニル、C1〜C6ハロアルキルカルボニル、フェニル(C1〜C4)アルキルカルボニル、(Z)p1によって置換されたフェニル(C1〜C4)アルキルカルボニル、C1〜C6アルコキシカルボニル、C1〜C6ハロアルコキシカルボニル、フェニル(C1〜C4)アルコキシカルボニル、(Z)p1によって置換されたフェニル(C1〜C4)アルコキシカルボニル、C1〜C6アルキルチオカルボニル、C1〜C6アルコキシチオカルボニル、C1〜C6アルキルアミノカルボニル、ジ(C1〜C6アルキル)アミノカルボニル、C1〜C6アルキルアミノチオカルボニル、ジ(C1〜C6アルキル)アミノチオカルボニル、フェニルカルボニル、(Z)p1によって置換されたフェニルカルボニル、C1〜C6アルキルスルホニル、C1〜C6ハロアルキルスルホニル、フェニルスルホニル、(Z)p1によって置換されたフェニルスルホニル、-P(O)(OR22)2又は-P(S)(OR22)2を表し、
R25は、ハロゲン原子、シアノ、C3〜C8シクロアルキル、C3〜C8ハロシクロアルキル、C1〜C6アルコキシ、C1〜C6ハロアルコキシ、C1〜C6アルキルチオ、C1〜C6ハロアルキルチオ、C1〜C6アルキルスルホニル、C1〜C6ハロアルキルスルホニル、C1〜C6アルキルアミノ、ジ(C1〜C6アルキル)アミノ、-CHO、C1〜C6アルキルカルボニル、C1〜C6ハロアルキルカルボニル、C1〜C6アルコキシカルボニル、C1〜C6ハロアルコキシカルボニル、-CH=NOR11、-C(R9)=NOR11、フェニル、(Z)p1によって置換されたフェニル、L又はMを表し、
R26は、水素原子、C1〜C8アルキル、R33によって任意に置換された(C1〜C8)アルキル、C3〜C8シクロアルキル、R33によって任意に置換された(C3〜C8)シクロアルキル、C3〜C8アルケニル、R33によって任意に置換された(C3〜C8)アルケニル、C3〜C8アルキニル、R33によって任意に置換された(C3〜C8)アルキニル、-CHO、-C(O)R29、-C(O)OR29、-C(O)SR29、-C(O)NHR30、-C(O)N(R30)R29、-C(O)C(O)R29、-C(O)C(O)OR29、-C(S)R29、-C(S)OR29、-C(S)SR29、-C(S)NHR30、-C(S)N(R30)R29、-S(O)2R29、-S(O)2N(R30)R29、-Si(R13)(R14)R12、-P(O)(OR22)2、-P(S)(OR22)2、フェニル、(Z)p1によって置換されたフェニル、L又はMを表し、
R27は、水素原子、C1〜C6アルキル、C1〜C6ハロアルキル、C3〜C6シクロアルキル又はC1〜C6アルコキシを表すか、或いは、R26とR27とが一緒になってC2〜C5アルキレン鎖を形成することにより、結合する窒素原子と共に３〜６員環を形成してもよいことを表し、このときこのアルキレン鎖は酸素原子又は硫黄原子を１個含んでもよく、且つハロゲン原子、C1〜C6アルキル基、C1〜C6アルコキシ基、フェニル基又は(Z)p1によって置換されたフェニル基によって置換されていてもよく、
R28は、C1〜C8アルキル、R33によって任意に置換された(C1〜C8)アルキル、C3〜C8シクロアルキル、R33によって任意に置換された(C3〜C8)シクロアルキル、C3〜C8アルケニル、R33によって任意に置換された(C3〜C8)アルケニル、C3〜C8アルキニル、R33によって任意に置換された(C3〜C8)アルキニル、-SH、C1〜C6アルキルチオ、C1〜C6ハロアルキルチオ、フェニルチオ、(Z)p1によって置換されたフェニルチオ、-CHO、-C(O)R29、-C(O)OR29、-C(O)SR29、-C(O)NHR30、-C(O)N(R30)R29、-C(O)C(O)R29、-C(O)C(O)OR29、-C(S)R29、-C(S)OR29、-C(S)SR29、-C(S)NHR30、-C(S)N(R30)R29、-P(O)(OR22)2、-P(S)(OR22)2、フェニル、(Z1)p1によって置換されたフェニル、L-18、L-21、L-25、L-30〜L-35、L-45、L-48、L-49又はMを表し、
R29は、C1〜C6アルキル、C1〜C6ハロアルキル、C3〜C8シクロアルキル(C1〜C4)アルキル、C1〜C6アルコキシ(C1〜C4)アルキル、C1〜C6ハロアルコキシ(C1〜C4)アルキル、C1〜C6アルキルチオ(C1〜C4)アルキル、C1〜C6ハロアルキルチオ(C1〜C4)アルキル、C1〜C6アルキルスルホニル(C1〜C4)アルキル、C1〜C6ハロアルキルスルホニル(C1〜C4)アルキル、シアノ(C1〜C6)アルキル、C1〜C6アルキルカルボニル(C1〜C4)アルキル、C1〜C6ハロアルキルカルボニル(C1〜C4)アルキル、C1〜C6アルコキシカルボニル(C1〜C4)アルキル、ジ(C1〜C6アルキル)アミノカルボニル(C1〜C4)アルキル、トリ(C1〜C4アルキル)シリル(C1〜C4)アルキル、フェニル(C1〜C4)アルキル、(Z)p1によって置換されたフェニル(C1〜C4)アルキル、L-(C1〜C4)アルキル、M-(C1〜C4)アルキル、C3〜C8シクロアルキル、C3〜C8ハロシクロアルキル、C2〜C6アルケニル、C2〜C6ハロアルケニル、C2〜C6アルキニル、C2〜C6ハロアルキニル、フェニル、(Z)p1によって置換されたフェニル、L又はMを表し、
R30は、水素原子、C1〜C6アルキル、C1〜C6ハロアルキル、フェニル又は(Z)p1によって置換されたフェニルを表すか、或いは、R29とR30とが一緒になってC2〜C5アルキレン鎖を形成することにより、結合する窒素原子と共に３〜６員環を形成してもよいことを表し、このときこのアルキレン鎖は酸素原子、硫黄原子又は窒素原子を１個含んでもよく、且つハロゲン原子、C1〜C6アルキル基、C1〜C6アルコキシ基、ホルミル基、C1〜C6アルキルカルボニル基、C1〜C6アルコキシカルボニル基、フェニル基又は(Z)p1によって置換されたフェニル基によって任意に置換されていてもよく、
R31は、水素原子、C1〜C8アルキル、R33によって任意に置換された(C1〜C8)アルキル、C3〜C8シクロアルキル、C3〜C8アルケニル、R33によって任意に置換された(C3〜C8)アルケニル、C3〜C8アルキニル又はR33によって任意に置換された(C3〜C8)アルキニルを表し、
R32は、水素原子、C1〜C6アルキル、C1〜C6ハロアルキル、C3〜C8シクロアルキル(C1〜C4)アルキル、C1〜C6アルコキシ(C1〜C4)アルキル、C1〜C6ハロアルコキシ(C1〜C4)アルキル、C1〜C6アルキルチオ(C1〜C4)アルキル、C1〜C6ハロアルキルチオ(C1〜C4)アルキル、C1〜C6アルキルスルホニル(C1〜C4)アルキル、C1〜C6ハロアルキルスルホニル(C1〜C4)アルキル、フェニル(C1〜C4)アルキル、(Z)p1によって置換されたフェニル(C1〜C4)アルキル、フェニル又は(Z)p1によって置換されたフェニルを表し、
R33は、ハロゲン原子、シアノ、ニトロ、C3〜C8シクロアルキル、C3〜C8ハロシクロアルキル、-OH、-OR34、-SH、-S(O)rR34、-NHR35、-N(R35)R34、-CHO、-C(O)R29、-C(O)OR29、-C(O)SR29、-C(O)NHR30、-C(O)N(R30)R29、-C(O)C(O)OR29、-CH=NOR11、-C(R9)=NOR11、-Si(R13)(R14)R12、-P(O)(OR22)2、-P(S)(OR22)2、-P(フェニル)2、-P(O)(フェニル)2、フェニル、(Z)p1によって置換されたフェニル、L又はMを表し、
R34は、C1〜C6アルキル、C1〜C6ハロアルキル、C1〜C6アルコキシ(C1〜C4)アルキル、C1〜C6アルキルチオ(C1〜C4)アルキル、フェニル(C1〜C4)アルキル、(Z)p1によって置換されたフェニル(C1〜C4)アルキル、C3〜C8シクロアルキル、C3〜C8ハロシクロアルキル、C3〜C6アルケニル、C3〜C6ハロアルケニル、C3〜C8シクロアルケニル、C3〜C8ハロシクロアルケニル、C3〜C6アルキニル、C3〜C6ハロアルキニル、-CHO、C1〜C6アルキルカルボニル、C1〜C6ハロアルキルカルボニル、C1〜C6アルコキシカルボニル、C1〜C6ハロアルコキシカルボニル、C1〜C6アルキルアミノカルボニル、ジ(C1〜C6アルキル)アミノカルボニル、フェニルカルボニル、(Z)p1によって置換されたフェニルカルボニル、C1〜C6アルキルアミノチオカルボニル、ジ(C1〜C6アルキル)アミノチオカルボニル、フェニル、(Z)p1によって置換されたフェニル、L又はMを表し、
R35は、水素原子、C1〜C6アルキル、C1〜C6ハロアルキル、C3〜C8シクロアルキル、C3〜C6アルケニル、C3〜C6アルキニル、C1〜C6アルキルカルボニル、C1〜C6ハロアルキルカルボニル、C1〜C6アルコキシカルボニル、C1〜C6ハロアルコキシカルボニル、フェノキシカルボニル、(Z)p1によって置換されたフェノキシカルボニル、フェニルカルボニル、(Z)p1によって置換されたフェニルカルボニル、C1〜C6アルキルスルホニル、C1〜C6ハロアルキルスルホニル、フェニル、(Z)p1によって置換されたフェニル、L又はMを表すか、或いは、R34とR35とが一緒になってC2〜C5アルキレン鎖を形成することにより、結合する窒素原子と共に３〜６員環を形成してもよいことを表し、このときこのアルキレン鎖は酸素原子又は硫黄原子を１個含んでもよく、且つハロゲン原子又はメチル基によって置換されていてもよく、
mは、０〜４の整数を表し、
nは、０〜４の整数を表し、
p1は、１〜５の整数を表し、
p2は、０〜４の整数を表し、
p3は、０〜３の整数を表し、
p4は、０〜２の整数を表し、
p5は、０又は１の整数を表し、
q1は、０〜３の整数を表し、
q2は、０〜５の整数を表し、
q3は、０〜７の整数を表し、
q4は、０〜９の整数を表し、
rは、０〜２の整数を表し、
tは、０又は１の整数を表す。］
で表される置換ベンズアニリド化合物又はその塩。 General formula (1):
Figure 2005126418
 [Wherein, W 1 and W 2 each independently represent an oxygen atom or a sulfur atom,
X is a halogen atom, cyano, nitro, azido, -SCN, -SF 5, C 1 ~C 6 alkyl, optionally substituted by R 7 (C 1 ~C 6) alkyl, C 3 -C 8 cycloalkyl , optionally substituted by R 7 (C 3 ~C 8) cycloalkyl, C 2 -C 6 alkenyl, optionally substituted by R 7 (C 2 ~C 6) alkenyl, C 3 -C 8 cycloalkenyl , C 3 -C 8 halocycloalkyl cycloalkenyl, C 2 -C 6 alkynyl, optionally substituted by R 7 (C 2 ~C 6) alkynyl, -OH, -OR 8, -OS ( O) 2 R 8, -SH, -S (O) r R 8 , -CHO, -C (O) R 9 , -C (O) OR 9 , -C (O) SR 9 , -C (O) NHR 10 , -C ( O) N (R 10 ) R 9 , -C (S) OR 9 , -C (S) SR 9 , -C (S) NHR 10 , -C (S) N (R 10 ) R 9 , -CH = NOR 11 , -C (R 9 ) = NOR 11 , -S (O) 2 OR 9 , -S (O) 2 NHR 10 , -S (O) 2 N (R 10 ) R 9 , -Si (R 13 ) (R 14) R 12, phenyl, (Z) phenyl substituted by p1, represents L or M, when m represents 2, 3 or 4, each X May be the or different from each other the same as each other,
Further, when two Xs are adjacent to each other, the two adjacent Xs are -CH 2 CH 2 CH 2- , -CH 2 CH 2 O-, -CH 2 OCH 2- , -OCH 2 O-, -CH 2 CH 2 S-, -CH 2 SCH 2- , -CH 2 CH 2 N (R 15 )-, -CH 2 N (R 15 ) CH 2- , -CH 2 CH 2 CH 2 CH 2- , -CH 2 CH 2 CH 2 O-, -CH 2 CH 2 OCH 2- , -CH 2 OCH 2 O-, -OCH 2 CH 2 O-, -OCH 2 CH 2 S-, -CH 2 CH = CH-,- OCH = CH-, -SCH = CH-, -N (R 15 ) CH = CH-, -OCH = N-, -SCH = N-, -N (R 15 ) CH = N-, -N (R 15 By forming N = CH-, -CH = CHCH = CH-, -OCH 2 CH = CH-, -N = CHCH = CH-, -N = CHCH = N- or -N = CHN = CH- A 5-membered ring or a 6-membered ring may be formed together with the carbon atom to which each of two Xs is bonded. At this time, the hydrogen atom bonded to each carbon atom forming the ring is optionally substituted by Z. In addition, when simultaneously substituted with two or more Z, each Z may be the same as or different from each other,
Y is a halogen atom, cyano, nitro, C 1 -C 6 alkyl, optionally substituted by R 7 (C 1 ~C 6) alkyl, C 3 -C 8 cycloalkyl, -OR 8, -S (O ) r R 8 , —NH 2 , C 1 -C 6 alkylamino, di (C 1 -C 6 alkyl) amino or —Si (R 13 ) (R 14 ) R 12 , n is 2, 3 or 4 Each Y may be the same as or different from each other;
Further, when two Ys are adjacent to each other, the two adjacent Ys are —CH 2 CH 2 CH 2 —, —CH 2 CH 2 O—, —CH 2 OCH 2 —, —OCH 2 O—, —CH 2 CH 2 S-, -CH 2 SCH 2- , -SCH 2 S-, -CH 2 CH 2 CH 2 CH 2- , -CH 2 CH 2 CH 2 O-, -CH 2 CH 2 OCH 2 -,- By forming CH 2 OCH 2 O-, -OCH 2 CH 2 O-, -OCH 2 CH 2 S-, -SCH 2 CH 2 S-, -OCH = N- or -SCH = N- A 5-membered ring or a 6-membered ring may be formed together with the carbon atom to which each Y is bonded, and at this time, the hydrogen atom bonded to each carbon atom forming the ring may be optionally substituted by Z Furthermore, when two or more Z are substituted at the same time, each Z may be the same as or different from each other,
R 1 is hydrogen atom, cyano, optionally substituted by C 1 -C 12 alkyl, optionally substituted by R 16 (C 1 ~C 12) alkyl, C 3 -C 12 cycloalkyl, R 16 ( C 3 -C 12) cycloalkyl, C 3 -C 12 alkenyl, optionally substituted by R 16 (C 3 ~C 12) alkenyl, C 3 -C 12 cycloalkenyl, C 3 -C 12 halo cycloalkenyl, C 3 -C 12 alkynyl, optionally substituted by R 16 (C 3 ~C 12) alkynyl, -OH, C 1 -C 8 alkoxy, C 3 -C 8 alkenyloxy, C 3 -C 8 haloalkenyloxy , phenoxy, (Z) p1 phenoxy substituted by phenyl (C 1 ~C 4) alkoxy, (Z) phenyl substituted by p1 (C 1 ~C 4) alkoxy, -N (R 20) R 19 , Phenyl, (Z) represents phenyl, L or M substituted by p1 ,
R 2 and R 3 are each independently a hydrogen atom, cyano, C 1 -C 12 alkyl, (C 1 -C 12 ) alkyl optionally substituted with R 16 , C 3 -C 12 alkenyl, C 3- C 12 haloalkenyl, C 3 -C 12 alkynyl, C 3 -C 12 haloalkynyl, -OH, C 1 -C 8 alkoxy, C 1 -C 6 alkylthio, C 1 -C 6 haloalkylthio, phenylthio, (Z) phenylthio substituted by p1, -S (O) 2 R 9, -SN (R 18) R 17, -S (O) 2 N (R 10) R 9, -N (R 20) R 19, -C (O) R 9 , -C (O) OR 9 , -C (O) SR 9 , -C (O) N (R 10 ) R 9 , -C (S) OR 9 , -C (S) SR 9 , -C (S) N (R 10) R 9, or represents phenyl which is substituted by phenyl or (Z) p1, or, R 2 is formed a C 2 -C 6 alkylene chain together with R 1 This represents that a 3- to 7-membered ring may be formed together with the nitrogen atom to be bonded. At this time, the alkylene chain has an oxygen atom, a sulfur atom or a nitrogen atom. Pieces comprise may, and halogen atom, C 1 -C 6 alkyl group, C 1 -C 6 haloalkyl group, C 1 -C 6 alkoxy group, C 1 -C 6 alkylcarbonyl group or a C 1 -C 6 alkoxycarbonyl group Optionally substituted by
R 4 is optionally substituted by C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, optionally substituted by R 21 (C 1 ~C 6) alkyl, R 21 (C 1 ~C 6) haloalkyl, C 3 -C 8 cycloalkyl, C 3 -C 8 halocycloalkyl, optionally substituted by R 21 (C 3 ~C 8) cycloalkyl, optionally substituted by R 21 (C 3 ~C 8) halocycloalkyl, C 3 -C 6 alkenyl, C 3 -C 6 haloalkenyl, C 3 -C 6 alkynyl, C 3 -C 6 haloalkynyl, phenyl, phenyl substituted by (Z) p1, L or Represents M,
R 5 is cyano, optionally substituted by R 21 (C 1 ~C 6) alkyl, optionally substituted by optionally substituted by R 21 (C 1 ~C 6) haloalkyl, R 21 (C 3 -C 8) cycloalkyl, optionally substituted optionally substituted by R 21 (C 3 ~C 8) halocycloalkyl, the R 21 (C 2 ~C 6) alkenyl, C 3 -C 8 cycloalkyl alkenyl, C 3 -C 8 halocycloalkyl cycloalkenyl, optionally substituted by R 21 (C 2 ~C 6) alkynyl, -OR 8, -S (O) r R 8, -N (R 10) R 9, -CHO, -C (O) R 9 , -CH = NOR 11 , -C (R 9 ) = NOR 11 , -C (O) OR 9 , -C (O) SR 9 , -C (O) NHR 10 , -C (O) N (R 10 ) R 9 , -C (S) OR 9 , -C (S) SR 9 , -C (S) NHR 10 , -C (S) N (R 10 ) R 9 , phenyl, (Z) phenyl substituted by p1, biphenyl, biphenyl substituted by (Z) p1, phenoxyphenyl, phenoxyphenyl substituted by (Z) p1, Pirijiruo Shifeniru, (Z) pyridyloxy phenyl substituted by p1, phenylthiophenyl, (Z) phenylthio phenyl substituted by p1, phenylsulfinyl phenyl, phenylsulfinyl phenyl substituted by (Z) p1, phenylsulfonyl phenyl, (Z) phenylsulfonyl phenyl substituted by p1, or represents L or M, or by forming a C 2 -C 3 alkylene chain together with Y being present on the adjacent position, it is condensed with a benzene ring Represents that a 5- to 6-membered ring may be formed, in which case the alkylene chain may contain one oxygen atom, sulfur atom or nitrogen atom, and optionally by a halogen atom or a C 1 -C 6 haloalkyl group May be replaced,
R 6 is a hydrogen atom, C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, optionally substituted by R 21 (C 1 ~C 6) alkyl, optionally substituted by R 21 (C 1 ~ C 6 ) haloalkyl, C 3 -C 8 cycloalkyl, C 3 -C 6 alkenyl, C 3 -C 6 haloalkenyl, phenyl (C 3 -C 6 ) alkenyl, (Z) phenyl substituted by p1 (C 3 -C 6) alkenyl, C 3 -C 8 cycloalkenyl, C 3 -C 6 alkynyl, C 3 -C 6 haloalkynyl, phenyl (C 3 ~C 6) alkynyl, phenyl substituted by (Z) p1 (C 3 -C 6) alkynyl, -S (O) 2 R 9 , -C (O) R 9, -C (O) OR 9, -C (O) SR 9, -C (S) OR 9, -C (S) SR 9 , -C (O) NHR 10 , -C (O) N (R 10 ) R 9 , -C (S) NHR 10 , -C (S) N (R 10 ) R 9 , -Si (R 13 ) (R 14 ) R 12 , -P (O) (OR 22 ) 2 , -P (S) (OR 22 ) 2 or M,
L represents an aromatic heterocycle represented by any one of formulas L-1 to L-58,
Figure 2005126418
Figure 2005126418
 M represents a saturated heterocyclic ring represented by any one of formulas M-1 to M-28;
Figure 2005126418
 Z is a halogen atom, cyano, nitro, azido, -SCN, -SF 5, C 1 ~C 6 alkyl, C 1 -C 6 haloalkyl, C 1 -C 3 alkoxy (C 1 ~C 3) alkyl, C 1 -C 3 haloalkoxy (C 1 ~C 3) alkyl, cyano (C 1 ~C 6) alkyl, hydroxy (C 1 ~C 3) haloalkyl, C 1 -C 3 alkoxy (C 1 ~C 3) haloalkyl, C 1 -C 3 haloalkoxy (C 1 ~C 3) haloalkyl, C 1 -C 3 alkylthio (C 1 ~C 3) alkyl, C 1 -C 3 haloalkylthio (C 1 ~C 3) alkyl, C 1 -C 3 alkylsulfinyl (C 1 -C 3) alkyl, C 1 -C 3 haloalkylsulfinyl (C 1 -C 3) alkyl, C 1 -C 3 alkylsulfonyl (C 1 -C 3) alkyl, C 1 -C 3 haloalkyl sulfonyl (C 1 ~C 3) alkyl, C 3 -C 8 cycloalkyl, C 3 -C 8 halocycloalkyl, C 2 -C 6 alkenyl, C 2 -C 6 haloalkenyl, C 3 -C 8 Cycloalkenyl, C 3 -C 8 halocycloalkyl cycloalkenyl, C 2 -C 6 alkynyl, C 2 -C 6 haloalkynyl, -OH, C 1 ~C 6 alkoxy, C 1 -C 6 haloalkoxy, C 1 -C 3 haloalkoxy (C 1 ~C 3) haloalkoxy, C 2 -C 6 alkenyloxy, C 2 -C 6 haloalkenyloxy, C 3 -C 6 alkynyloxy, C 3 -C 6 haloalkynyloxy, C 1 -C 6 alkylsulfonyloxy, C 1 -C 6 haloalkylsulfonyloxy, -SH, C 1 ~C 6 alkylthio, C 1 -C 6 haloalkylthio, C 1 -C 6 alkylsulfinyl, C 1 -C 6 haloalkylsulfinyl, C 1 -C 6 alkylsulfonyl, C 1 -C 6 haloalkylsulfonyl, -NH 2, C 1 ~C 6 alkyl amino, di (C 1 -C 6 alkyl) amino, C 1 -C 6 alkylsulfonylamino, C 1 -C 6 haloalkylsulfonyl amino, C 1 -C 6 an alkoxycarbonyl Boniru, C 1 -C 6 haloalkoxycarbonyl, -C (O) NH 2, C 1 ~C 6 alkylaminocarbonyl, di (C 1 -C 6 alkyl) aminocarbonyl, -C (S) NH 2, C 1 -C 6 alkylaminosulfonyl, di (C 1 -C 6 alkyl) aminosulfonyl or a tri (C 1 -C 6 alkyl) a silyl, when p1, p2, p3 or p4 represents an integer of 2 or more, each of the Z may be the same as or different from each other,
Further, when two Zs are adjacent to each other, the two adjacent Zs are -CH 2 CH 2 CH 2- , -CH 2 CH 2 O-, -CH 2 OCH 2- , -OCH 2 O-, -CH 2 CH 2 S-, -CH 2 SCH 2- , -CH 2 CH 2 CH 2 CH 2 CH 2- , -CH 2 CH 2 CH 2 O-, -CH 2 CH 2 OCH 2- , -CH 2 OCH 2 O- , -OCH 2 CH 2 O-, -OCH 2 CH 2 S- or -CH = CHCH = CH- to form a 5-membered or 6-membered ring with the carbon atom to which each of the two Z bonds may be, at this time, the hydrogen atoms bonded to each carbon atom forming the ring may be optionally substituted by halogen atom or C 1 -C 6 alkyl group,
R 7 is a halogen atom, cyano, C 3 to C 8 cycloalkyl, C 3 to C 8 halocycloalkyl, —OH, —OR 8 , —SH, —S (O) r R 8 , —N (R 10 ) R 9 , -N (R 10 ) CHO, -N (R 10 ) C (O) R 9 , -N (R 10 ) C (O) OR 9 , -N (R 10 ) C (O) SR 9 , -N (R 10 ) C (S) OR 9 , -N (R 10 ) C (S) SR 9 , -N (R 10 ) S (O) 2 R 9 , -C (O) OR 9 ,- C (O) N (R 10 ) R 9 , -Si (R 13 ) (R 14 ) R 12 , phenyl, (Z) represents phenyl, L or M substituted by p1 ;
R 8 is optionally substituted by C 1 -C 6 alkyl, optionally substituted by R 25 (C 1 ~C 6) alkyl, C 3 -C 8 cycloalkyl, R 25 (C 3 ~C 8 ) cycloalkyl, C 2 -C 6 alkenyl, optionally substituted by R 25 (C 2 ~C 6) alkenyl, C 3 -C 8 cycloalkenyl, C 3 -C 8 halocycloalkyl cycloalkenyl, C 3 -C 6 It represents alkynyl, optionally substituted by R 25 (C 3 ~C 6) alkynyl, phenyl, phenyl, L or M, which is substituted by (Z) p1,
R 9 is C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, C 3 -C 6 cycloalkyl (C 1 -C 4 ) alkyl, C 1 -C 6 alkoxy (C 1 -C 4 ) alkyl, C 1 -C 6 alkylthio (C 1 ~C 4) alkyl, cyano (C 1 ~C 6) alkyl, phenyl (C 1 ~C 4) alkyl, (Z) phenyl substituted by p1 (C 1 ~C 4) Alkyl, L- (C 1 -C 4 ) alkyl, M- (C 1 -C 4 ) alkyl, C 3 -C 8 cycloalkyl, C 3 -C 8 halocycloalkyl, C 3 -C 6 alkenyl, C 3 -C 6 represents haloalkenyl, C 3 -C 6 alkynyl, phenyl substituted by phenyl or (Z) p1,
R 10 represents a hydrogen atom or C 1 -C 6 alkyl, or R 9 and R 10 together form a C 2 -C 6 alkylene chain to form 3-7 together with the atoms to be bonded. indicates that the members may form a ring, this time the alkylene chain an oxygen atom, may contain one sulfur atom or a nitrogen atom, and a halogen atom, C 1 -C 6 alkyl group, C 1 -C 6 alkoxy group, a formyl group, may be optionally substituted by C 1 -C 6 alkylcarbonyl group or a C 1 -C 6 alkoxycarbonyl group,
R 11 represents a hydrogen atom, C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, phenyl (C 1 ~C 4) alkyl, (Z) phenyl substituted by p1 (C 1 ~C 4) alkyl, C 3 -C 6 alkenyl, C 3 -C 6 haloalkenyl, or represents C 3 -C 6 alkynyl or C 3 -C 6 haloalkynyl, or, R 11 is C 2 -C 4 alkylene together with R 9 By forming a chain, it represents that a 5- to 7-membered ring may be formed together with the atoms to be bonded. At this time, the alkylene chain may contain one oxygen atom, sulfur atom or nitrogen atom, and a halogen atom. or it may be optionally substituted by C 1 -C 6 alkyl group,
R 12 represents C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, C 3 -C 6 alkenyl, phenyl or phenyl substituted by (Z) p1 ;
R 13 and R 14 each independently represent C 1 -C 6 alkyl or C 1 -C 6 haloalkyl,
R 15 is a hydrogen atom, C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, C 1 -C 6 alkoxycarbonyl (C 1 -C 4 ) alkyl, C 1 -C 6 haloalkoxycarbonyl (C 1 -C 4) alkyl, phenyl (C 1 -C 4) alkyl, (Z) phenyl substituted by p1 (C 1 -C 4) alkyl, C 3 -C 6 alkenyl, C 3 -C 6 haloalkenyl, C 3 ~ C 6 represents alkynyl, C 3 -C 6 haloalkynyl, C 1 -C 6 alkoxy, C 1 -C 6 alkoxycarbonyl, C 1 -C 6 haloalkoxycarbonyl, phenyl substituted by phenyl or (Z) p1,
R 16 is a halogen atom, cyano, nitro, C 3 -C 8 cycloalkyl, C 3 -C 8 halocycloalkyl, -OR 26 , -N (R 27 ) R 26 , -SH, -S (O) r R 28 , -SO 2 NHR 30 , -SO 2 N (R 30 ) R 29 , -CHO, -C (O) R 29 , -C (O) OH, -C (O) OR 29 , -C (O ) SR 29 , -C (O) NHR 30 , -C (O) N (R 30 ) R 29 , -C (O) C (O) OR 29 , -C (R 32 ) = NOH, -C (R 32 ) = NOR 31 , -Si (R 13 ) (R 14 ) R 12 , -P (O) (OR 22 ) 2 , -P (S) (OR 22 ) 2 , -P (phenyl) 2 , -P (O) (phenyl) 2 , phenyl, (Z) represents phenyl, L or M substituted by p1 ,
R 17 is C 1 -C 12 alkyl, C 1 -C 12 haloalkyl, C 1 -C 12 alkoxy (C 1 -C 12 ) alkyl, cyano (C 1 -C 12 ) alkyl, C 1 -C 12 alkoxycarbonyl (C 1 ~C 12) alkyl, phenyl (C 1 ~C 4) alkyl, (Z) phenyl substituted by p1 (C 1 ~C 4) alkyl, C 3 -C 12 alkenyl, C 3 -C 12 halo represents alkenyl, C 3 -C 12 alkynyl, C 3 -C 12 haloalkynyl, C 1 -C 12 alkylcarbonyl, C 1 -C 12 alkoxycarbonyl, phenyl substituted by phenyl or (Z) p1,
R 18 is C 1 -C 12 alkyl, C 1 -C 12 haloalkyl, C 1 -C 12 alkoxy (C 1 -C 12 ) alkyl, cyano (C 1 -C 12 ) alkyl, C 1 -C 12 alkoxycarbonyl (C 1 ~C 12) alkyl, phenyl (C 1 ~C 4) alkyl, (Z) phenyl substituted by p1 (C 1 ~C 4) alkyl, C 3 -C 12 alkenyl, C 3 -C 12 halo alkenyl, C 3 -C 12 alkynyl, C 3 -C 12 haloalkynyl, or represents phenyl which is substituted by phenyl or (Z) p1, or, C 4 -C 7 and R 17 and R 18 together By forming an alkylene chain, it represents that a 5- to 8-membered ring may be formed together with the nitrogen atom to be bonded. At this time, the alkylene chain may contain one oxygen atom or sulfur atom, and C 1- It may be optionally substituted by C 4 alkyl group or a C 1 -C 4 alkoxy group,
R 19 is a hydrogen atom, C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, phenyl (C 1 ~C 4) alkyl, (Z) phenyl substituted by p1 (C 1 ~C 4) alkyl, C 3 -C 6 alkenyl, C 3 -C 6 haloalkenyl, C 3 -C 6 alkynyl, -CHO, C 1 ~C 6 alkyl carbonyl, C 1 -C 6 haloalkylcarbonyl, C 1 -C 6 alkoxycarbonyl, C 1 -C 6 haloalkoxycarbonyl, phenyl (C 1 ~C 4) alkoxycarbonyl, (Z) phenyl substituted by p1 (C 1 ~C 4) alkoxycarbonyl, phenoxycarbonyl, phenoxycarbonyl substituted by (Z) p1 , Phenylcarbonyl, phenylcarbonyl substituted by (Z) p1 , phenyl or phenyl substituted by (Z) p1 ,
R 20 represents a hydrogen atom, C 1 -C 6 alkyl, -CHO, C 1 -C 6 alkylcarbonyl, a C 1 -C 6 haloalkylcarbonyl or C 1 -C 6 alkoxycarbonyl,
R 21 is cyano, C 3 to C 8 cycloalkyl, C 3 to C 8 halocycloalkyl, —OH, —OR 8 , —SH, —S (O) r R 8 , —N (R 10 ) R 9 , -N (R 10 ) CHO, -N (R 10 ) C (O) R 9 , -N (R 10 ) C (O) OR 9 , -N (R 10 ) C (O) SR 9 , -N (R 10 ) C (S) OR 9 , -N (R 10 ) C (S) SR 9 , -N (R 10 ) S (O) 2 R 9 , -C (O) OR 9 , -C (O ) N (R 10 ) R 9 , -Si (R 13 ) (R 14 ) R 12 , phenyl, (Z) represents phenyl, L or M substituted by p1 ;
R 22 represents C 1 -C 6 alkyl or C 1 -C 6 haloalkyl,
R 23 is a halogen atom, cyano, C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, hydroxy (C 1 -C 6 ) alkyl, C 1 -C 4 alkoxy (C 1 -C 4 ) alkyl, C 1 -C 4 alkoxycarbonyl (C 1 ~C 4) represents alkyl, C 1 -C 6 alkoxy, C 1 -C 6 alkoxycarbonyl, phenyl substituted by phenyl or (Z) p1, q1, q2 , q3 or q4 When each represents an integer of 2 or more, each R 23 may be the same as or different from each other;
R 24 is a hydrogen atom, C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, -CHO, C 1 -C 6 alkylcarbonyl, C 1 -C 6 haloalkylcarbonyl, phenyl (C 1 ~C 4) alkylcarbonyl (Z) phenyl (C 1 -C 4 ) alkylcarbonyl, C 1 -C 6 alkoxycarbonyl, C 1 -C 6 haloalkoxycarbonyl, phenyl (C 1 -C 4 ) alkoxycarbonyl, substituted by p1 (Z ) phenyl substituted by p1 (C 1 ~C 4) alkoxycarbonyl, C 1 -C 6 alkylthiocarbonyl, C 1 -C 6 alkoxythiocarbonyl, C 1 -C 6 alkylaminocarbonyl, di (C 1 -C 6 alkyl) aminocarbonyl, C 1 -C 6 alkylamino thiocarbonyl, di (C 1 -C 6 alkyl) aminothiocarbonyl, phenylcarbonyl, (Z) phenylcarbonyl substituted by p1, C 1 -C 6 alkyl sulfonyl Represents C 1 -C 6 haloalkylsulfonyl, phenylsulfonyl, and (Z) phenylsulfonyl substituted by p1, -P (O) (OR 22) 2 or -P (S) (OR 22) 2,
R 25 is a halogen atom, cyano, C 3 -C 8 cycloalkyl, C 3 -C 8 halocycloalkyl, C 1 -C 6 alkoxy, C 1 -C 6 haloalkoxy, C 1 -C 6 alkylthio, C 1 -C 6 haloalkylthio, C 1 -C 6 alkylsulfonyl, C 1 -C 6 haloalkylsulfonyl, C 1 -C 6 alkylamino, di (C 1 -C 6 alkyl) amino, -CHO, C 1 -C 6 alkyl carbonyl, C 1 -C 6 haloalkylcarbonyl, C 1 -C 6 alkoxycarbonyl, C 1 -C 6 haloalkoxycarbonyl, -CH = NOR 11, -C ( R 9) = NOR 11, phenyl, the (Z) p1 Represents substituted phenyl, L or M;
R 26 is a hydrogen atom, C 1 -C 8 alkyl, optionally substituted by R 33 (C 1 ~C 8) alkyl, C 3 -C 8 cycloalkyl, optionally substituted by R 33 (C 3 -C 8) cycloalkyl, C 3 -C 8 alkenyl, optionally substituted by R 33 (C 3 ~C 8) alkenyl, optionally substituted by C 3 -C 8 alkynyl, R 33 (C 3 ~ C 8 ) alkynyl, -CHO, -C (O) R 29 , -C (O) OR 29 , -C (O) SR 29 , -C (O) NHR 30 , -C (O) N (R 30 ) R 29 , -C (O) C (O) R 29 , -C (O) C (O) OR 29 , -C (S) R 29 , -C (S) OR 29 , -C (S) SR 29 , -C (S) NHR 30 , -C (S) N (R 30 ) R 29 , -S (O) 2 R 29 , -S (O) 2 N (R 30 ) R 29 , -Si (R 13 ) (R 14 ) R 12 , -P (O) (OR 22 ) 2 , -P (S) (OR 22 ) 2 , phenyl, (Z) represents phenyl, L or M substituted by p1 ;
R 27 represents a hydrogen atom, C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, C 3 -C 6 cycloalkyl or C 1 -C 6 alkoxy, or R 26 and R 27 together by now it forms a C 2 -C 5 alkylene chain, represents that may form a 3-6 membered ring together with the nitrogen atom to which they are attached this case the alkylene chain may contain one oxygen atom or a sulfur atom But often, and halogen atom, C 1 -C 6 alkyl group, C 1 -C 6 alkoxy group, a phenyl group or (Z) p1 may be substituted by a phenyl group substituted by,
R 28 is, C 1 -C 8 alkyl, optionally substituted by R 33 (C 1 ~C 8) alkyl, optionally substituted by C 3 -C 8 cycloalkyl, R 33 (C 3 ~C 8 ) cycloalkyl, optionally substituted by C 3 -C 8 alkenyl, R 33 (C 3 ~C 8 ) alkenyl, optionally substituted by C 3 -C 8 alkynyl, R 33 (C 3 ~C 8 ) alkynyl, -SH, C 1 -C 6 alkylthio, C 1 -C 6 haloalkylthio, phenylthio, phenylthio substituted by (Z) p1, -CHO, -C (O) R 29, -C (O) OR 29 , -C (O) SR 29 , -C (O) NHR 30 , -C (O) N (R 30 ) R 29 , -C (O) C (O) R 29 , -C (O) C (O ) OR 29 , -C (S) R 29 , -C (S) OR 29 , -C (S) SR 29 , -C (S) NHR 30 , -C (S) N (R 30 ) R 29 ,- P (O) (OR 22 ) 2 , -P (S) (OR 22 ) 2 , phenyl, phenyl substituted by (Z 1 ) p1 , L-18, L-21, L-25, L-30 ~ Represents L-35, L-45, L-48, L-49 or M;
R 29 is C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, C 3 -C 8 cycloalkyl (C 1 -C 4 ) alkyl, C 1 -C 6 alkoxy (C 1 -C 4 ) alkyl, C 1 -C 6 haloalkoxy (C 1 ~C 4) alkyl, C 1 -C 6 alkylthio (C 1 ~C 4) alkyl, C 1 -C 6 haloalkylthio (C 1 ~C 4) alkyl, C 1 -C 6 alkylsulfonyl (C 1 ~C 4) alkyl, C 1 -C 6 haloalkylsulfonyl (C 1 ~C 4) alkyl, cyano (C 1 -C 6) alkyl, C 1 -C 6 alkylcarbonyl (C 1 -C 4) alkyl, C 1 -C 6 haloalkylcarbonyl (C 1 -C 4) alkyl, C 1 -C 6 alkoxycarbonyl (C 1 -C 4) alkyl, di (C 1 -C 6 alkyl) aminocarbonyl (C 1 -C 4) alkyl, tri (C 1 -C 4 alkyl) silyl (C 1 -C 4) alkyl, phenyl (C 1 -C 4) alkyl, phenyl substituted by (Z) p1 (C 1 ~C 4 ) alkyl, L- (C 1 C 4) alkyl, M- (C 1 ~C 4) alkyl, C 3 -C 8 cycloalkyl, C 3 -C 8 halocycloalkyl, C 2 -C 6 alkenyl, C 2 -C 6 haloalkenyl, C 2 -C 6 alkynyl, C 2 -C 6 haloalkynyl, represents phenyl, phenyl, L or M, which is substituted by (Z) p1,
R 30 represents a hydrogen atom, C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, phenyl or phenyl substituted by (Z) p 1 , or R 29 and R 30 together represent C By forming a 2 to C 5 alkylene chain, it represents that a 3 to 6 membered ring may be formed together with the nitrogen atom to be bonded. At this time, this alkylene chain contains one oxygen atom, sulfur atom or nitrogen atom. But often, and halogen atom, C 1 -C 6 alkyl group, C 1 -C 6 alkoxy group, a formyl group, C 1 -C 6 alkylcarbonyl group, C 1 -C 6 alkoxycarbonyl group, a phenyl group or (Z) optionally substituted by a phenyl group substituted by p1 ,
R 31 is hydrogen atom, C 1 -C 8 alkyl, (C 1 -C 8 ) alkyl optionally substituted by R 33 , C 3 -C 8 cycloalkyl, C 3 -C 8 alkenyl, optional by R 33 substituted a (C 3 ~C 8) alkenyl, optionally substituted by C 3 -C 8 alkynyl, or R 33 (C 3 ~C 8) alkynyl,
R 32 is a hydrogen atom, C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, C 3 -C 8 cycloalkyl (C 1 ~C 4) alkyl, C 1 -C 6 alkoxy (C 1 ~C 4) alkyl, C 1 -C 6 haloalkoxy (C 1 ~C 4) alkyl, C 1 -C 6 alkylthio (C 1 ~C 4) alkyl, C 1 -C 6 haloalkylthio (C 1 ~C 4) alkyl, C 1 -C 6 alkylsulfonyl (C 1 ~C 4) alkyl, C 1 -C 6 haloalkylsulfonyl (C 1 ~C 4) alkyl, phenyl (C 1 ~C 4) alkyl, phenyl substituted by (Z) p1 (C 1 ~C 4) represents alkyl, phenyl substituted by phenyl or (Z) p1,
R 33 is a halogen atom, cyano, nitro, C 3 -C 8 cycloalkyl, C 3 -C 8 halocycloalkyl, —OH, —OR 34 , —SH, —S (O) r R 34 , —NHR 35 , -N (R 35 ) R 34 , -CHO, -C (O) R 29 , -C (O) OR 29 , -C (O) SR 29 , -C (O) NHR 30 , -C (O) N (R 30 ) R 29 , -C (O) C (O) OR 29 , -CH = NOR 11 , -C (R 9 ) = NOR 11 , -Si (R 13 ) (R 14 ) R 12 ,- P (O) (OR 22 ) 2 , -P (S) (OR 22 ) 2 , -P (phenyl) 2 , -P (O) (phenyl) 2 , phenyl, phenyl substituted by (Z) p1 , L or M represents
R 34 is C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, C 1 -C 6 alkoxy (C 1 -C 4 ) alkyl, C 1 -C 6 alkylthio (C 1 -C 4 ) alkyl, phenyl ( C 1 -C 4) alkyl, (Z) phenyl substituted by p1 (C 1 ~C 4) alkyl, C 3 -C 8 cycloalkyl, C 3 -C 8 halocycloalkyl, C 3 -C 6 alkenyl, C 3 -C 6 haloalkenyl, C 3 -C 8 cycloalkenyl, C 3 -C 8 halocycloalkyl cycloalkenyl, C 3 -C 6 alkynyl, C 3 -C 6 haloalkynyl, -CHO, C 1 ~C 6 alkyl carbonyl , C 1 -C 6 haloalkylcarbonyl, C 1 -C 6 alkoxycarbonyl, C 1 -C 6 haloalkoxycarbonyl, C 1 -C 6 alkylaminocarbonyl, di (C 1 -C 6 alkyl) aminocarbonyl, phenylcarbonyl, (Z) phenylcarbonyl substituted by p1, C 1 ~C 6 alkylaminothiocarbonyl It represents di (C 1 -C 6 alkyl) aminothiocarbonyl, phenyl, phenyl, L or M, which is substituted by (Z) p1,
R 35 represents a hydrogen atom, C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, C 3 -C 8 cycloalkyl, C 3 -C 6 alkenyl, C 3 -C 6 alkynyl, C 1 -C 6 alkylcarbonyl , C 1 -C 6 haloalkylcarbonyl, C 1 -C 6 alkoxycarbonyl, C 1 -C 6 haloalkoxycarbonyl, phenoxycarbonyl, phenoxycarbonyl substituted by (Z) p1, phenylcarbonyl, substituted by (Z) p1 phenylcarbonyl, C 1 -C 6 alkylsulfonyl and, C 1 -C 6 haloalkylsulfonyl, phenyl, phenyl substituted by (Z) p1, or represents L or M, or the R 34 and R 35 together form by now it forms a C 2 -C 5 alkylene chain, represents that may form a 3-6 membered ring together with the nitrogen atom to which they are attached this case the alkylene chain may contain one oxygen atom or a sulfur atom so May, be substituted and the halogen atom or a methyl group,
m represents an integer of 0 to 4,
n represents an integer of 0 to 4,
p1 represents an integer of 1 to 5,
p2 represents an integer of 0 to 4,
p3 represents an integer of 0 to 3,
p4 represents an integer of 0 to 2,
p5 represents an integer of 0 or 1,
q1 represents an integer of 0 to 3,
q2 represents an integer of 0 to 5,
q3 represents an integer of 0 to 7,
q4 represents an integer of 0 to 9,
r represents an integer of 0 to 2;
t represents an integer of 0 or 1. ]
The substituted benzanilide compound or its salt represented by these. W1及びW2は、酸素原子を表し、
Xは、ハロゲン原子、シアノ、ニトロ、C1〜C6アルキル、C1〜C6ハロアルキル、C1〜C6アルコキシ、C1〜C6ハロアルコキシ、C1〜C6アルキルスルホニルオキシ、C1〜C6ハロアルキルスルホニルオキシ、C1〜C6アルキルチオ、C1〜C6ハロアルキルチオ、C1〜C6アルキルスルフィニル、C1〜C6ハロアルキルスルフィニル、C1〜C6アルキルスルホニル又はC1〜C6ハロアルキルスルホニルを表し、mが２又は３を表すとき、各々のXは互いに同一であっても又は互いに相異なっていてもよく、
さらに、２つのXが隣接する場合には、隣接する２つのXは-OCH2O-又は-OCH2CH2O-を形成することにより、それぞれが結合する炭素原子と共に５員環又は６員環を形成してもよく、このとき、環を形成する各々の炭素原子に結合した水素原子はハロゲン原子、C1〜C4アルキル基又はC1〜C4ハロアルキル基によって任意に置換されていてもよく、
Yは、ハロゲン原子、C1〜C6アルキル、C1〜C6ハロアルキル、ヒドロキシ(C1〜C6)アルキル、C1〜C3アルコキシ(C1〜C3)アルキル、C1〜C6アルコキシ、C1〜C6ハロアルコキシ、C1〜C6アルキルチオ、C1〜C6ハロアルキルチオ、C1〜C6アルキルアミノ又はジ(C1〜C6アルキル)アミノを表し、nが２又は３を表すとき、各々のYは互いに同一であっても又は互いに相異なっていてもよく、
R1は、C1〜C8アルキル、R16によって任意に置換された(C1〜C8)アルキル、C3〜C8シクロアルキル、C3〜C8アルケニル、C3〜C8アルキニル、C1〜C8アルコキシ、M-4、M-5、M-8、M-9、M-13〜M-19、M-21又はM-22を表し、
R2及びR3は、各々独立して水素原子、C1〜C6アルキル、C1〜C4アルコキシ(C1〜C4)アルキル、C1〜C4アルキルチオ(C1〜C4)アルキル、C1〜C4アルキルスルホニル(C1〜C4)アルキル、C3〜C6アルケニル、C3〜C6アルキニル、C1〜C6アルキルチオ、C1〜C6ハロアルキルチオ、フェニルチオ、(Z)p1によって置換されたフェニルチオ又は-SN(R18)R17を表すか、或いは、R2はR1と一緒になってC2〜C6アルキレン鎖を形成することにより、結合する窒素原子と共に３〜７員環を形成してもよいことを表し、このときこのアルキレン鎖は酸素原子又は硫黄原子を１個含んでもよく、
R4は、C1〜C6アルキル、C1〜C6ハロアルキル、R21によって任意に置換された(C1〜C6)アルキル、R21によって任意に置換された(C1〜C6)ハロアルキル、C3〜C8シクロアルキル、C3〜C8ハロシクロアルキル、C3〜C6ハロアルケニル、C3〜C6ハロアルキニル、フェニル又は(Z)p1によって置換されたフェニルを表し、
R5は、シアノ、R21によって任意に置換された(C1〜C6)アルキル、R21によって任意に置換された(C1〜C6)ハロアルキル、C3〜C8シクロアルキル、C3〜C8ハロシクロアルキル、R21によって任意に置換された(C2〜C6)アルケニル、R21によって任意に置換された(C2〜C6)アルキニル、-C(O)OR9、-C(O)SR9、-C(O)NHR10、-C(O)N(R10)R9、-C(S)OR9、-C(S)SR9、-C(S)NHR10、-C(S)N(R10)R9、フェニル、(Z)p1によって置換されたフェニル、(Z)p1によって置換されたフェノキシフェニル、(Z)p1によって置換されたピリジルオキシフェニル、L-1〜L-4、L-8〜L-13、L-15〜L-23、L-25〜L-35、L-37、L-38、L-40、L-43〜L-58、M-4、M-5、M-8、M-9、M-14〜M-18又はM-19を表すか、或いは、隣接位に存在するYと一緒になってC2〜C3アルキレン鎖を形成することにより、ベンゼン環と縮合する５〜６員環を形成してもよいことを表し、このときこのアルキレン鎖は酸素原子、硫黄原子又は窒素原子を１個含んでもよく、且つハロゲン原子又はC1〜C6ハロアルキル基によって任意に置換されていてもよく、
R6は、水素原子、C1〜C6アルキル、C1〜C6ハロアルキル、C1〜C4アルコキシ(C1〜C4)アルキル、C1〜C4アルキルチオ(C1〜C4)アルキル、シアノ(C1〜C6)アルキル、フェニル(C1〜C4)アルキル、(Z)p1によって置換されたフェニル(C1〜C4)アルキル、C3〜C6アルケニル、C3〜C6ハロアルケニル、フェニル(C3〜C6)アルケニル、(Z)p1によって置換されたフェニル(C3〜C6)アルケニル、C3〜C6アルキニル、C3〜C6ハロアルキニル、フェニル(C3〜C6)アルキニル、(Z)p1によって置換されたフェニル(C3〜C6)アルキニル、-S(O)2R9、-C(O)R9、-C(O)NHR10、-C(O)N(R10)R9、-C(S)NHR10、-C(S)N(R10)R9、-Si(R13)(R14)R12、-P(O)(OR22)2又は-P(S)(OR22)2を表し、
Zは、ハロゲン原子、シアノ、ニトロ、C1〜C6アルキル、C1〜C6ハロアルキル、C1〜C3アルキルチオ(C1〜C3)アルキル、C1〜C3ハロアルキルチオ(C1〜C3)アルキル、C1〜C3アルキルスルフィニル(C1〜C3)アルキル、C1〜C3ハロアルキルスルフィニル(C1〜C3)アルキル、C1〜C3アルキルスルホニル(C1〜C3)アルキル、C1〜C3ハロアルキルスルホニル(C1〜C3)アルキル、C1〜C6アルコキシ、C1〜C6ハロアルコキシ、C1〜C3ハロアルコキシ(C1〜C3)ハロアルコキシ、C1〜C6アルキルスルホニルオキシ、C1〜C6ハロアルキルスルホニルオキシ、C1〜C6アルキルチオ、C1〜C6ハロアルキルチオ、C1〜C6アルキルスルフィニル、C1〜C6ハロアルキルスルフィニル、C1〜C6アルキルスルホニル、C1〜C6ハロアルキルスルホニル、-C(O)NH2又は-C(S)NH2を表し、p1, p2, p3又はp4が２以上の整数を表すとき、各々のZは互いに同一であっても又は互いに相異なっていてもよく、
さらに、２つのZが隣接する場合には、隣接する２つのZは-CF2CF2O-, -CF2OCF2-, -OCF2O-, -OCF2CHFO-, -OCF2CF2O-又は-CH=CHCH=CH-を形成することにより、２つのZのそれぞれが結合する炭素原子と共に５員環又は６員環を形成してもよく、
R9は、C1〜C6アルキル、C1〜C6ハロアルキル、C3〜C6シクロアルキル(C1〜C4)アルキル、フェニル(C1〜C4)アルキル、(Z)p1によって置換されたフェニル(C1〜C4)アルキル、C3〜C8シクロアルキル、C3〜C8ハロシクロアルキル、フェニル又は(Z)p1によって置換されたフェニルを表し、
R10は、水素原子又はC1〜C6アルキルを表すか、或いは、R9とR10とが一緒になってC4〜C5アルキレン鎖を形成することにより、結合する窒素原子と共に５員環又は６員環を形成してもよいことを表し、このときこのアルキレン鎖は酸素原子又は硫黄原子を１個含んでもよく、
R12は、C1〜C6アルキル、フェニル又は(Z)p1によって置換されたフェニルを表し、
R13及びR14は、各々独立してC1〜C6アルキルを表し、
R15は、C1〜C6アルキル、C1〜C6ハロアルキル、フェニル(C1〜C4)アルキル、(Z)p1によって置換されたフェニル(C1〜C4)アルキル、フェニル又は(Z)p1によって置換されたフェニルを表し、
R16は、ハロゲン原子、シアノ、C3〜C6シクロアルキル、-OR26、-N(R27)R26、-S(O)rR28、-SO2N(R30)R29、C1〜C6アルコキシカルボニル、-C(O)N(R30)R29、-C(R32)=NOH、-C(R32)=NOR31、-Si(R13)(R14)R12、フェニル、(Z)p1によって置換されたフェニル、L-1、L-2、L-3、L-4、L-45、L-46、L-47又はMを表し、
R17は、C1〜C6アルキル、C1〜C6アルコキシカルボニル(C1〜C4)アルキル又はC1〜C6アルコキシカルボニルを表し、
R18は、C1〜C6アルキルを表すか、或いは、R17とR18とが一緒になってC4〜C5アルキレン鎖を形成することにより、結合する窒素原子と共に５員環又は６員環を形成してもよいことを表し、このときこのアルキレン鎖は酸素原子又は硫黄原子１個を含んでもよく、且つメチル基又はメトキシ基によって任意に置換されていてもよく、
R21は、シアノ、C3〜C6シクロアルキル、C3〜C6ハロシクロアルキル、C1〜C6アルコキシ、C1〜C6ハロアルコキシ、フェノキシ、(Z)p1によって置換されたフェノキシ、C1〜C6アルキルチオ、C1〜C6ハロアルキルチオ、フェニルチオ、(Z)p1によって置換されたフェニルチオ、C1〜C6アルキルスルフィニル、C1〜C6ハロアルキルスルフィニル、C1〜C6アルキルスルホニル、C1〜C6ハロアルキルスルホニル、フェニルスルホニル、(Z)p1によって置換されたフェニルスルホニル、C1〜C6アルキルアミノ、ジ(C1〜C6アルキル)アミノ、フェニルアミノ、(Z)p1によって置換されたフェニルアミノ、C1〜C6アルコキシカルボニル、フェニル、(Z)p1によって置換されたフェニル、L-1〜L-5、L-8〜L-24、L-36、L-39、L-45〜L-52又はL-53を表し、
R22は、C1〜C6アルキルを表し、
R23は、C1〜C4アルキルを表し、q1, q2, q3又はq4が２以上の整数を表すとき、各々のR23は互いに同一であっても、または互いに相異なっていてもよく、
R24は、-CHO、C1〜C6アルキルカルボニル、C1〜C6アルコキシカルボニル又はC1〜C6アルキルスルホニルを表し、
R26は、水素原子、C1〜C6アルキル、C1〜C6ハロアルキル、C1〜C4アルコキシ(C1〜C4)アルキル、C1〜C4アルキルチオ(C1〜C4)アルキル、フェニル(C1〜C4)アルキル、(Z)p1によって置換されたフェニル(C1〜C4)アルキル、C1〜C6アルキルカルボニル、C1〜C6ハロアルキルカルボニル、C3〜C6シクロアルキルカルボニル、C1〜C6アルコキシカルボニル、-C(O)N(R30)R29、C1〜C6アルキルスルホニル、ジ(C1〜C6アルキル)アミノスルホニル、フェニルスルホニル、(Z)p1によって置換されたフェニルスルホニル、ジ(C1〜C6アルキル)ホスホリル、ジ(C1〜C6アルキル)チオホスホリル、トリ(C1〜C4アルキル)シリル、フェニル又は(Z)p1によって置換されたフェニルを表し、
R27は、水素原子又はC1〜C6アルキルを表し、
R28は、C1〜C6アルキル、C1〜C6ハロアルキル、ヒドロキシ(C1〜C4)アルキル、C1〜C4アルコキシ(C1〜C4)アルキル、C1〜C4アルキルチオ(C1〜C4)アルキル、C1〜C4アルキルカルボニル(C1〜C4)アルキル、C1〜C4アルコキシカルボニル(C1〜C4)アルキル、C1〜C4アルキルアミノカルボニル(C1〜C4)アルキル、ジ(C1〜C4アルキル)アミノカルボニル(C1〜C4)アルキル、トリ(C1〜C4アルキル)シリル(C1〜C4)アルキル、フェニル(C1〜C4)アルキル、(Z)p1によって置換されたフェニル(C1〜C4)アルキル、C3〜C6アルケニル、C3〜C6アルキニル、C1〜C6アルキルチオ、フェニル、(Z)p1によって置換されたフェニル、L-21、L-35、L-45又はL-48を表し、
R29は、C1〜C6アルキル、C1〜C4アルコキシ(C1〜C4)アルキル、C1〜C4アルキルチオ(C1〜C4)アルキル、フェニル(C1〜C4)アルキル、(Z)p1によって置換されたフェニル(C1〜C4)アルキル、C3〜C6シクロアルキル、C3〜C6アルケニル、C2〜C6アルキニル、フェニル又は(Z)p1によって置換されたフェニルを表し、
R30は、水素原子又はC1〜C6アルキルを表すか、或いは、R29とR30とが一緒になってC2〜C5アルキレン鎖を形成することにより、結合する窒素原子と共に３〜６員環を形成してもよいことを表し、このときこのアルキレン鎖は酸素原子又は硫黄原子を１個含んでもよく、
R31は、C1〜C6アルキル、フェニル(C1〜C4)アルキル又は(Z)p1によって置換されたフェニル(C1〜C4)アルキルを表し、
R32は、水素原子又はC1〜C6アルキルを表し、
mは、０〜３の整数を表し、
nは、０〜３の整数を表し、
q2、q3及びq4は、各々独立して０〜２の整数を表す請求項１記載の置換ベンズアニリド化合物又はその塩。 W 1 and W 2 represent an oxygen atom,
X is a halogen atom, cyano, nitro, C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, C 1 -C 6 alkoxy, C 1 -C 6 haloalkoxy, C 1 -C 6 alkylsulfonyloxy, C 1 -C 6 haloalkylsulfonyloxy, C 1 -C 6 alkylthio, C 1 -C 6 haloalkylthio, C 1 -C 6 alkylsulfinyl, C 1 -C 6 haloalkylsulfinyl, C 1 -C 6 alkylsulfonyl or C 1 -C 6 represents haloalkylsulfonyl, and when m represents 2 or 3, each X may be the same as or different from each other;
Further, when two Xs are adjacent to each other, the two adjacent Xs form —OCH 2 O— or —OCH 2 CH 2 O— to form a 5-membered ring or 6-membered together with the carbon atom to which each is bonded. may form a ring, this time, the hydrogen atoms bonded to each carbon atom forming the ring is optionally substituted by halogen atom, C 1 -C 4 alkyl or C 1 -C 4 haloalkyl group Well,
Y is a halogen atom, C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, hydroxy (C 1 ~C 6) alkyl, C 1 -C 3 alkoxy (C 1 ~C 3) alkyl, C 1 -C 6 alkoxy, C 1 -C 6 represents haloalkoxy, C 1 -C 6 alkylthio, C 1 -C 6 haloalkylthio, a C 1 -C 6 alkylamino or di (C 1 -C 6 alkyl) amino, n is 2 or 3 may be the same as or different from each other,
R 1 is C 1 -C 8 alkyl, (C 1 -C 8 ) alkyl optionally substituted by R 16 , C 3 -C 8 cycloalkyl, C 3 -C 8 alkenyl, C 3 -C 8 alkynyl, C 1 -C 8 -alkoxy, a M-4, M-5, M-8, M-9, M-13~M-19, M-21 or M-22,
R 2 and R 3 are each independently a hydrogen atom, C 1 -C 6 alkyl, C 1 -C 4 alkoxy (C 1 -C 4 ) alkyl, C 1 -C 4 alkylthio (C 1 -C 4 ) alkyl. , C 1 -C 4 alkylsulfonyl (C 1 ~C 4) alkyl, C 3 -C 6 alkenyl, C 3 -C 6 alkynyl, C 1 -C 6 alkylthio, C 1 -C 6 haloalkylthio, phenylthio, (Z ) represents phenylthio substituted by p1 or —SN (R 18 ) R 17 , or R 2 together with R 1 forms a C 2 -C 6 alkylene chain, together with the nitrogen atom to which it is attached. Represents that a 3- to 7-membered ring may be formed, in which case this alkylene chain may contain one oxygen or sulfur atom,
R 4 is optionally substituted by C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, optionally substituted by R 21 (C 1 ~C 6) alkyl, R 21 (C 1 ~C 6) represents haloalkyl, C 3 -C 8 cycloalkyl, C 3 -C 8 halocycloalkyl, C 3 -C 6 haloalkenyl, C 3 -C 6 haloalkynyl, phenyl substituted by phenyl or (Z) p1,
R 5 is cyano, optionally substituted by R 21 (C 1 ~C 6) alkyl, optionally substituted by R 21 (C 1 ~C 6) haloalkyl, C 3 -C 8 cycloalkyl, C 3 -C 8 halocycloalkyl, optionally substituted by R 21 (C 2 ~C 6) alkenyl, optionally substituted by R 21 (C 2 ~C 6) alkynyl, -C (O) OR 9, - C (O) SR 9 , -C (O) NHR 10 , -C (O) N (R 10 ) R 9 , -C (S) OR 9 , -C (S) SR 9 , -C (S) NHR 10, -C (S) N ( R 10) R 9, phenyl, (Z) phenyl substituted by p1, (Z) phenoxyphenyl phenyl substituted by p1, pyridyloxy phenyl substituted by (Z) p1, L-1 ~ L-4, L-8 ~ L-13, L-15 ~ L-23, L-25 ~ L-35, L-37, L-38, L-40, L-43 ~ L- 58, M-4, M-5, M-8, M-9, M-14 to M-18 or M-19, or C 2 to C together with Y present in the adjacent position by forming a 3 alkylene chain, condensed with a benzene ring 5 Membered indicates that may form a ring, this time the alkylene chain an oxygen atom, may contain one sulfur atom or a nitrogen atom, optionally substituted and the halogen atom or a C 1 -C 6 haloalkyl group You can,
R 6 is a hydrogen atom, C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, C 1 -C 4 alkoxy (C 1 -C 4 ) alkyl, C 1 -C 4 alkylthio (C 1 -C 4 ) alkyl , cyano (C 1 ~C 6) alkyl, phenyl (C 1 ~C 4) alkyl, phenyl (C 1 ~C 4) substituted by (Z) p1 alkyl, C 3 -C 6 alkenyl, C 3 -C 6 haloalkenyl, phenyl (C 3 -C 6) alkenyl, (Z) phenyl substituted by p1 (C 3 -C 6) alkenyl, C 3 -C 6 alkynyl, C 3 -C 6 haloalkynyl, phenyl (C 3 -C 6 ) alkynyl, phenyl (C 3 -C 6 ) alkynyl substituted by (Z) p1 , -S (O) 2 R 9 , -C (O) R 9 , -C (O) NHR 10 , -C (O) N (R 10 ) R 9 , -C (S) NHR 10 , -C (S) N (R 10 ) R 9 , -Si (R 13 ) (R 14 ) R 12 , -P ( O) (OR 22 ) 2 or -P (S) (OR 22 ) 2
Z is a halogen atom, cyano, nitro, C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, C 1 -C 3 alkylthio (C 1 ~C 3) alkyl, C 1 -C 3 haloalkylthio (C 1 ~ C 3) alkyl, C 1 -C 3 alkylsulfinyl (C 1 ~C 3) alkyl, C 1 -C 3 haloalkylsulfinyl (C 1 ~C 3) alkyl, C 1 -C 3 alkylsulfonyl (C 1 -C 3 ) alkyl, C 1 -C 3 haloalkylsulfonyl (C 1 -C 3) alkyl, C 1 -C 6 alkoxy, C 1 -C 6 haloalkoxy, C 1 -C 3 haloalkoxy (C 1 -C 3) haloalkoxy , C 1 -C 6 alkylsulfonyloxy, C 1 -C 6 haloalkylsulfonyloxy, C 1 -C 6 alkylthio, C 1 -C 6 haloalkylthio, C 1 -C 6 alkylsulfinyl, C 1 -C 6 haloalkylsulfinyl, C 1 -C 6 alkylsulfonyl, C 1 -C 6 haloalkylsulfonyl, -C (O) NH 2 or - Represents C (S) NH 2, and when p1, p2, p3 or p4 represents an integer of 2 or more, each Z may be the same as or different from each other;
Further, when two Zs are adjacent, the two adjacent Zs are -CF 2 CF 2 O-, -CF 2 OCF 2- , -OCF 2 O-, -OCF 2 CHFO-, -OCF 2 CF 2 By forming O- or -CH = CHCH = CH-, a 5-membered ring or a 6-membered ring may be formed together with the carbon atom to which each of two Zs is bonded,
R 9 is C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, C 3 -C 6 cycloalkyl (C 1 -C 4 ) alkyl, phenyl (C 1 -C 4 ) alkyl, (Z) substituted by p1 phenyl (C 1 ~C 4) represents alkyl, C 3 -C 8 cycloalkyl, C 3 -C 8 halocycloalkyl, phenyl substituted by phenyl or (Z) p1,
R 10 represents a hydrogen atom or C 1 -C 6 alkyl, or R 9 and R 10 together form a C 4 -C 5 alkylene chain to form a 5-membered atom together with the nitrogen atom to which it is attached. Represents that a ring or a 6-membered ring may be formed, in which case the alkylene chain may contain one oxygen atom or sulfur atom,
R 12 represents C 1 -C 6 alkyl, phenyl or phenyl substituted by (Z) p 1
R 13 and R 14 each independently represent C 1 -C 6 alkyl;
R 15 is, C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, phenyl (C 1 ~C 4) alkyl, phenyl (C 1 ~C 4) substituted by (Z) p1 alkyl, phenyl or (Z ) represents phenyl substituted by p1 ,
R 16 is a halogen atom, cyano, C 3 -C 6 cycloalkyl, -OR 26 , -N (R 27 ) R 26 , -S (O) r R 28 , -SO 2 N (R 30 ) R 29 , C 1 -C 6 alkoxycarbonyl, -C (O) N (R 30) R 29, -C (R 32) = NOH, -C (R 32) = NOR 31, -Si (R 13) (R 14) R 12 represents phenyl, phenyl substituted by (Z) p1 , L-1, L-2, L-3, L-4, L-45, L-46, L-47 or M;
R 17 represents C 1 -C 6 alkyl, C 1 -C 6 alkoxycarbonyl (C 1 -C 4 ) alkyl or C 1 -C 6 alkoxycarbonyl,
R 18 represents C 1 -C 6 alkyl, or R 17 and R 18 together form a C 4 -C 5 alkylene chain to form a 5-membered ring or 6 together with the nitrogen atom to which R 18 is bonded. The alkylene chain may contain one oxygen atom or one sulfur atom, and may be optionally substituted with a methyl group or a methoxy group,
R 21 is cyano, C 3 -C 6 cycloalkyl, C 3 -C 6 halocycloalkyl, C 1 -C 6 alkoxy, C 1 -C 6 haloalkoxy, phenoxy, (Z) phenoxy substituted by p 1 , C 1 -C 6 alkylthio, C 1 -C 6 haloalkylthio, phenylthio, (Z) phenylthio substituted by p1, C 1 -C 6 alkylsulfinyl, C 1 -C 6 haloalkylsulfinyl, C 1 -C 6 alkylsulfonyl , C 1 -C 6 haloalkylsulfonyl, phenylsulfonyl, phenylsulfonyl substituted by (Z) p1, C 1 ~C 6 alkyl amino, di (C 1 -C 6 alkyl) amino, phenylamino, by (Z) p1 substituted phenylamino, C 1 -C 6 alkoxycarbonyl, phenyl, (Z) phenyl substituted by p1, L-1~L-5, L-8~L-24, L-36, L-39, Represents L-45 to L-52 or L-53,
R 22 represents C 1 -C 6 alkyl;
R 23 represents C 1 -C 4 alkyl, and when q1, q2, q3 or q4 represents an integer of 2 or more, each R 23 may be the same as or different from each other;
R 24 represents -CHO, C 1 -C 6 alkylcarbonyl, a C 1 -C 6 alkoxycarbonyl or C 1 -C 6 alkylsulfonyl,
R 26 is a hydrogen atom, C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, C 1 -C 4 alkoxy (C 1 -C 4 ) alkyl, C 1 -C 4 alkylthio (C 1 -C 4 ) alkyl , phenyl (C 1 ~C 4) alkyl, (Z) phenyl substituted by p1 (C 1 ~C 4) alkyl, C 1 -C 6 alkylcarbonyl, C 1 -C 6 haloalkylcarbonyl, C 3 -C 6 cycloalkylcarbonyl, C 1 -C 6 alkoxycarbonyl, -C (O) N (R 30) R 29, C 1 ~C 6 alkyl sulfonyl, di (C 1 -C 6 alkyl) aminosulfonyl, phenylsulfonyl, (Z ) phenylsulfonyl substituted by p1, di (C 1 -C 6 alkyl) phosphoryl, di (C 1 -C 6 alkyl) thiophosphoryl, tri (C 1 -C 4 alkyl) silyl, by phenyl or (Z) p1 Represents substituted phenyl,
R 27 represents a hydrogen atom or a C 1 -C 6 alkyl,
R 28 is C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, hydroxy (C 1 -C 4 ) alkyl, C 1 -C 4 alkoxy (C 1 -C 4 ) alkyl, C 1 -C 4 alkylthio ( C 1 -C 4) alkyl, C 1 -C 4 alkylcarbonyl (C 1 -C 4) alkyl, C 1 -C 4 alkoxycarbonyl (C 1 -C 4) alkyl, C 1 -C 4 alkylaminocarbonyl (C 1 -C 4) alkyl, di (C 1 -C 4 alkyl) aminocarbonyl (C 1 -C 4) alkyl, tri (C 1 -C 4 alkyl) silyl (C 1 -C 4) alkyl, phenyl (C 1 -C 4) alkyl, (Z) phenyl substituted by p1 (C 1 ~C 4) alkyl, C 3 -C 6 alkenyl, C 3 -C 6 alkynyl, C 1 -C 6 alkylthio, phenyl, (Z) represents phenyl, L-21, L-35, L-45 or L-48 substituted by p1 ,
R 29 is C 1 -C 6 alkyl, C 1 -C 4 alkoxy (C 1 -C 4 ) alkyl, C 1 -C 4 alkylthio (C 1 -C 4 ) alkyl, phenyl (C 1 -C 4 ) alkyl. It is replaced by (Z) phenyl substituted by p1 (C 1 ~C 4) alkyl, C 3 -C 6 cycloalkyl, C 3 -C 6 alkenyl, C 2 -C 6 alkynyl, phenyl or (Z) p1 Represents phenyl,
R 30 represents a hydrogen atom or C 1 to C 6 alkyl, or R 29 and R 30 together form a C 2 to C 5 alkylene chain to form a 3- Represents that a 6-membered ring may be formed, in which case the alkylene chain may contain one oxygen or sulfur atom,
R 31 is, C 1 -C 6 alkyl, phenyl (C 1 ~C 4) phenyl substituted by alkyl or (Z) p1 (C 1 ~C 4) alkyl,
R 32 represents a hydrogen atom or C 1 -C 6 alkyl,
m represents an integer of 0 to 3,
n represents an integer of 0 to 3,
The substituted benzanilide compound or a salt thereof according to claim 1, wherein q2, q3 and q4 each independently represents an integer of 0 to 2. Xは、ハロゲン原子、ニトロ、C1〜C6アルキル、C1〜C6ハロアルキル、C1〜C6アルコキシ、C1〜C6ハロアルコキシ、C1〜C6アルキルスルホニルオキシ、C1〜C6アルキルチオ、C1〜C6ハロアルキルチオ、C1〜C6アルキルスルフィニル、C1〜C6ハロアルキルスルフィニル、C1〜C6アルキルスルホニル又はC1〜C6ハロアルキルスルホニルを表し、mが２を表すとき、各々のXは互いに同一であっても又は互いに相異なっていてもよく、
Yは、ハロゲン原子、C1〜C6アルキル、C1〜C6ハロアルキル、C1〜C6アルコキシ又はC1〜C6アルキルチオを表し、nが２を表すとき、各々のYは互いに同一であっても又は互いに相異なっていてもよく、
R1は、C1〜C8アルキル、R16によって任意に置換された(C1〜C8)アルキル、C3〜C8アルケニル又はC3〜C8アルキニルを表し、
R2は、水素原子又はC1〜C6アルキルを表し、
R3は、水素原子を表し、
R4は、C1〜C6アルキル、C1〜C6ハロアルキル、C1〜C3アルコキシ(C1〜C3)ハロアルキル、C1〜C3アルキルチオ(C1〜C3)ハロアルキル、C3〜C6シクロアルキル又はC3〜C6ハロシクロアルキルを表し、
R5は、R21によって任意に置換された(C1〜C6)アルキル、R21によって任意に置換された(C1〜C6)ハロアルキル、R21によって任意に置換された(C2〜C6)アルケニル、R21によって任意に置換された(C2〜C6)アルキニル、C1〜C6アルコキシカルボニル、フェニル、(Z)p1によって置換されたフェニル、(Z)p1によって置換されたフェノキシフェニル、(Z)p1によって置換されたピリジルオキシフェニル、L-1〜L-4、L-8〜L-13、L-15〜L-23、L-45〜L-52又はL-53を表すか、或いは、隣接位に存在するYと一緒になってC2〜C3アルキレン鎖を形成することにより、ベンゼン環と縮合する５〜６員環を形成してもよいことを表し、このときこのアルキレン鎖は酸素原子、硫黄原子又は窒素原子を１個含んでもよく、且つハロゲン原子によって任意に置換されていてもよく、
R6は、水素原子、C1〜C6アルキル、C1〜C4アルコキシ(C1〜C4)アルキル、C1〜C6アルキルカルボニル又はトリ(C1〜C4アルキル)シリルを表し、
R16は、-OR26、-N(R27)R26、-S(O)rR28、-SO2N(R30)R29、-C(R32)=NOH又は-C(R32)=NOR31を表し、
R21は、C1〜C6アルコキシ、C1〜C6ハロアルコキシ、フェノキシ、(Z)p1によって置換されたフェノキシ、フェニルチオ、(Z)p1によって置換されたフェニルチオ、フェニルスルホニル、(Z)p1によって置換されたフェニルスルホニル、C1〜C6アルキルアミノ、ジ(C1〜C6アルキル)アミノ、フェニルアミノ、(Z)p1によって置換されたフェニルアミノ、C1〜C6アルコキシカルボニル、フェニル、(Z)p1によって置換されたフェニル、L-1〜L-5、L-8〜L-24、L-36、L-39、L-45〜L-52又はL-53を表し、
R26は、水素原子、C1〜C6アルキル、C1〜C6アルキルカルボニル、C1〜C6アルコキシカルボニル、C1〜C6アルキルアミノカルボニル、ジ(C1〜C6アルキル)アミノカルボニル又はC1〜C6アルキルスルホニルを表し、
R28は、C1〜C6アルキルを表し、
R29は、C1〜C6アルキルを表し、
R30は、水素原子又はC1〜C6アルキルを表し、
R31は、C1〜C6アルキルを表し、
R32は、水素原子を表し、
mは、０〜２の整数を表し、
nは、０〜２の整数を表す請求項２記載の置換ベンズアニリド化合物又はその塩。 X is a halogen atom, nitro, C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, C 1 -C 6 alkoxy, C 1 -C 6 haloalkoxy, C 1 -C 6 alkylsulfonyloxy, C 1 -C 6 alkylthio, C 1 -C 6 haloalkylthio, C 1 -C 6 alkylsulfinyl, C 1 -C 6 haloalkylsulfinyl, C 1 -C 6 alkylsulfonyl or C 1 -C 6 haloalkylsulfonyl, m represents 2 Each X may be the same or different from each other,
Y is a halogen atom, C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, C 1 -C 6 alkoxy or C 1 -C 6 alkylthio, when n is 2, each Y is identical to each other May be different from each other,
R 1 represents C 1 -C 8 alkyl, (C 1 -C 8 ) alkyl, C 3 -C 8 alkenyl or C 3 -C 8 alkynyl optionally substituted by R 16 ,
R 2 represents a hydrogen atom or C 1 -C 6 alkyl,
R 3 represents a hydrogen atom,
R 4 is C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, C 1 -C 3 alkoxy (C 1 -C 3 ) haloalkyl, C 1 -C 3 alkylthio (C 1 -C 3 ) haloalkyl, C 3 -C 6 cycloalkyl or C 3 -C 6 halocycloalkyl,
R 5 is optionally substituted by R 21 (C 1 ~C 6) alkyl, optionally substituted by R 21 (C 1 ~C 6) haloalkyl, optionally substituted by R 21 (C 2 ~ C 6) alkenyl, optionally substituted by R 21 (C 2 ~C 6) alkynyl, C 1 -C 6 alkoxycarbonyl, phenyl, phenyl substituted by (Z) p1, substituted by (Z) p1 Phenoxyphenyl, pyridyloxyphenyl substituted by (Z) p1 , L-1 to L-4, L-8 to L-13, L-15 to L-23, L-45 to L-52 or L-53 or it represents, or indicates that by forming a C 2 -C 3 alkylene chain together with Y being present on the adjacent positions, may form a 5- or 6-membered ring fused with a benzene ring, In this case, the alkylene chain may contain one oxygen atom, sulfur atom or nitrogen atom, and may be optionally substituted with a halogen atom. ,
R 6 represents a hydrogen atom, C 1 -C 6 alkyl, C 1 -C 4 alkoxy (C 1 -C 4 ) alkyl, C 1 -C 6 alkylcarbonyl or tri (C 1 -C 4 alkyl) silyl;
R 16 is -OR 26 , -N (R 27 ) R 26 , -S (O) r R 28 , -SO 2 N (R 30 ) R 29 , -C (R 32 ) = NOH or -C (R 32 ) = NOR 31
R 21 is, C 1 -C 6 alkoxy, C 1 -C 6 haloalkoxy, phenoxy, (Z) p1 phenoxy substituted by, phenylthio, phenylthio substituted by (Z) p1, phenylsulfonyl, (Z) p1 phenylsulfonyl substituted by, C 1 -C 6 alkylamino, di (C 1 -C 6 alkyl) amino, phenylamino, (Z) phenylamino substituted by p1, C 1 -C 6 alkoxycarbonyl, phenyl, (Z) represents phenyl substituted by p1 , L-1 to L-5, L-8 to L-24, L-36, L-39, L-45 to L-52 or L-53;
R 26 is a hydrogen atom, C 1 -C 6 alkyl, C 1 -C 6 alkylcarbonyl, C 1 -C 6 alkoxycarbonyl, C 1 -C 6 alkylaminocarbonyl, di (C 1 -C 6 alkyl) aminocarbonyl or represents C 1 -C 6 alkylsulfonyl,
R 28 represents C 1 -C 6 alkyl,
R 29 represents C 1 -C 6 alkyl;
R 30 represents a hydrogen atom or C 1 -C 6 alkyl,
R 31 represents C 1 -C 6 alkyl;
R 32 represents a hydrogen atom,
m represents an integer of 0 to 2,
The substituted benzanilide compound or a salt thereof according to claim 2, wherein n represents an integer of 0 to 2. Xは、ハロゲン原子、ニトロ、C1〜C4アルキル、C1〜C4ハロアルキル、C1〜C4アルキルチオ、C1〜C4アルキルスルフィニル又はC1〜C4アルキルスルホニルを表し、mが２を表すとき、各々のXは互いに同一であっても又は互いに相異なっていてもよく、
Yは、ハロゲン原子又はC1〜C4アルキルを表し、nが２を表すとき、各々のYは互いに同一であっても又は互いに相異なっていてもよく、
R1は、C1〜C8アルキル、C1〜C4アルキルチオ(C1〜C4)アルキル、C1〜C4アルキルスルフィニル(C1〜C4)アルキル又はC1〜C4アルキルスルホニル(C1〜C4)アルキルを表し、
R2は、水素原子を表し、
R4は、C1〜C6アルキル又はC1〜C6ハロアルキルを表し、
R5は、フェニル、(Z)p1によって置換されたフェニル、(Z)p1によって置換されたフェノキシフェニル、(Z)p1によって置換されたピリジルオキシフェニル、L-1〜L-4、L-8〜L-13、L-15〜L-23、L-45〜L-52又はL-53を表し、
R6は、水素原子を表す請求項３記載の置換ベンズアニリド化合物又はその塩。 X represents a halogen atom, nitro, C 1 -C 4 alkyl, C 1 -C 4 haloalkyl, C 1 -C 4 alkylthio, a C 1 -C 4 alkylsulfinyl or C 1 -C 4 alkylsulfonyl, m is 2 Each X may be the same as or different from each other;
Y represents a halogen atom or a C 1 -C 4 alkyl, when n is 2, each Y may be the even or different from each other the same as each other,
R 1 is C 1 -C 8 alkyl, C 1 -C 4 alkylthio (C 1 -C 4 ) alkyl, C 1 -C 4 alkylsulfinyl (C 1 -C 4 ) alkyl or C 1 -C 4 alkylsulfonyl ( C 1 -C 4) alkyl,
R 2 represents a hydrogen atom,
R 4 represents C 1 -C 6 alkyl or C 1 -C 6 haloalkyl,
R 5 is phenyl, (Z) phenyl substituted by p1, (Z) phenoxyphenyl phenyl substituted by p1, (Z) pyridyloxy phenyl substituted by p1, L-1~L-4, L-8 ~ L-13, L-15 ~ L-23, L-45 ~ L-52 or L-53,
The substituted benzanilide compound or a salt thereof according to claim 3, wherein R 6 represents a hydrogen atom. 一般式（２）又は一般式（３）：
Figure 2005126418
 ［式中、Y1は、水素原子、ハロゲン原子、C1〜C6アルキル、C1〜C6ハロアルキル、C1〜C6アルコキシ又はC1〜C6アルキルチオを表し、
Y2及びY3は、各々独立して水素原子を表すか、或いは、R5と一緒になってC2〜C3アルキレン鎖を形成することにより、ベンゼン環と縮合する５〜６員環を形成してもよいことを表し、このときこのアルキレン鎖は酸素原子、硫黄原子又は窒素原子を１個含んでもよく、且つハロゲン原子によって任意に置換されていてもよく、
R4は、C1〜C6アルキル、C1〜C6ハロアルキル、C1〜C3アルコキシ(C1〜C3)ハロアルキル、C1〜C3アルキルチオ(C1〜C3)ハロアルキル、C3〜C6シクロアルキル又はC3〜C6ハロシクロアルキルを表し、
R5は、R21によって任意に置換された(C1〜C6)アルキル、R21によって任意に置換された(C1〜C6)ハロアルキル、R21によって任意に置換された(C2〜C6)アルケニル、R21によって任意に置換された(C2〜C6)アルキニル、C1〜C6アルコキシカルボニル、フェニル、(Z)p1によって置換されたフェニル、(Z)p1によって置換されたフェノキシフェニル、(Z)p1によって置換されたピリジルオキシフェニル、L-1〜L-4、L-8〜L-13、L-15〜L-23、L-45〜L-52又はL-53を表し、
R6は、水素原子、C1〜C6アルキル、C1〜C4アルコキシ(C1〜C4)アルキル、C1〜C6アルキルカルボニル又はトリ(C1〜C4アルキル)シリルを表し、
R21は、C1〜C6アルコキシ、C1〜C6ハロアルコキシ、フェノキシ、(Z)p1によって置換されたフェノキシ、フェニルチオ、(Z)p1によって置換されたフェニルチオ、フェニルスルホニル、(Z)p1によって置換されたフェニルスルホニル、C1〜C6アルキルアミノ、ジ(C1〜C6アルキル)アミノ、フェニルアミノ、(Z)p1によって置換されたフェニルアミノ、C1〜C6アルコキシカルボニル、フェニル、(Z)p1によって置換されたフェニル、L-1〜L-5、L-8〜L-24、L-36、L-39、L-45〜L-52又はL-53を表し、
L-1〜L-5、L-8〜L-24、L-36、L-39、L-45〜L-52又はL-53は、それぞれ下記の芳香族複素環を表し、
Figure 2005126418
Figure 2005126418
 Zは、ハロゲン原子、シアノ、ニトロ、C1〜C6アルキル、C1〜C6ハロアルキル、C1〜C3アルキルチオ(C1〜C3)アルキル、C1〜C3ハロアルキルチオ(C1〜C3)アルキル、C1〜C3アルキルスルフィニル(C1〜C3)アルキル、C1〜C3ハロアルキルスルフィニル(C1〜C3)アルキル、C1〜C3アルキルスルホニル(C1〜C3)アルキル、C1〜C3ハロアルキルスルホニル(C1〜C3)アルキル、C1〜C6アルコキシ、C1〜C6ハロアルコキシ、C1〜C3ハロアルコキシ(C1〜C3)ハロアルコキシ、C1〜C6アルキルスルホニルオキシ、C1〜C6ハロアルキルスルホニルオキシ、C1〜C6アルキルチオ、C1〜C6ハロアルキルチオ、C1〜C6アルキルスルフィニル、C1〜C6ハロアルキルスルフィニル、C1〜C6アルキルスルホニル、C1〜C6ハロアルキルスルホニル、-C(O)NH2又は-C(S)NH2を表し、p1, p2, p3又はp4が２以上の整数を表すとき、各々のZは互いに同一であっても又は互いに相異なっていてもよく、
さらに、２つのZが隣接する場合には、隣接する２つのZは-CF2CF2O-, -CF2OCF2-, -OCF2O-, -OCF2CHFO-, -OCF2CF2O-又は-CH=CHCH=CH-を形成することにより、２つのZのそれぞれが結合する炭素原子と共に５員環又は６員環を形成してもよく、
R15は、C1〜C6アルキル、フェニル又は(Z)p1によって置換されたフェニルを表し、
p1は、１〜５の整数を表し、
p2は、０〜４の整数を表し、
p3は、０〜３の整数を表し、
p4は、０〜２の整数を表し、
p5は、０又は１の整数を表し、
rは、０〜２の整数を表し、
tは、０又は１の整数を表す。］
で表されるＮ−置換フェニル−３−ニトロフタルイミド若しくは置換アニリン又はそれらの塩。 General formula (2) or general formula (3):
Figure 2005126418
 [Wherein Y 1 represents a hydrogen atom, a halogen atom, C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, C 1 -C 6 alkoxy or C 1 -C 6 alkylthio,
Y 2 and Y 3 each independently represent a hydrogen atom, or, together with R 5 , form a C 2 -C 3 alkylene chain to form a 5- to 6-membered ring condensed with a benzene ring. The alkylene chain may contain one oxygen atom, sulfur atom or nitrogen atom, and may be optionally substituted with a halogen atom,
R 4 is C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, C 1 -C 3 alkoxy (C 1 -C 3 ) haloalkyl, C 1 -C 3 alkylthio (C 1 -C 3 ) haloalkyl, C 3 -C 6 cycloalkyl or C 3 -C 6 halocycloalkyl,
R 5 is optionally substituted by R 21 (C 1 ~C 6) alkyl, optionally substituted by R 21 (C 1 ~C 6) haloalkyl, optionally substituted by R 21 (C 2 ~ C 6) alkenyl, optionally substituted by R 21 (C 2 ~C 6) alkynyl, C 1 -C 6 alkoxycarbonyl, phenyl, phenyl substituted by (Z) p1, substituted by (Z) p1 Phenoxyphenyl, pyridyloxyphenyl substituted by (Z) p1 , L-1 to L-4, L-8 to L-13, L-15 to L-23, L-45 to L-52 or L-53 Represents
R 6 represents a hydrogen atom, C 1 -C 6 alkyl, C 1 -C 4 alkoxy (C 1 -C 4 ) alkyl, C 1 -C 6 alkylcarbonyl or tri (C 1 -C 4 alkyl) silyl;
R 21 is, C 1 -C 6 alkoxy, C 1 -C 6 haloalkoxy, phenoxy, (Z) p1 phenoxy substituted by, phenylthio, phenylthio substituted by (Z) p1, phenylsulfonyl, (Z) p1 phenylsulfonyl substituted by, C 1 -C 6 alkylamino, di (C 1 -C 6 alkyl) amino, phenylamino, (Z) phenylamino substituted by p1, C 1 -C 6 alkoxycarbonyl, phenyl, (Z) represents phenyl substituted by p1 , L-1 to L-5, L-8 to L-24, L-36, L-39, L-45 to L-52 or L-53;
L-1 to L-5, L-8 to L-24, L-36, L-39, L-45 to L-52 or L-53 each represents the following aromatic heterocycle:
Figure 2005126418
Figure 2005126418
 Z is a halogen atom, cyano, nitro, C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, C 1 -C 3 alkylthio (C 1 ~C 3) alkyl, C 1 -C 3 haloalkylthio (C 1 ~ C 3) alkyl, C 1 -C 3 alkylsulfinyl (C 1 ~C 3) alkyl, C 1 -C 3 haloalkylsulfinyl (C 1 ~C 3) alkyl, C 1 -C 3 alkylsulfonyl (C 1 -C 3 ) alkyl, C 1 -C 3 haloalkylsulfonyl (C 1 -C 3) alkyl, C 1 -C 6 alkoxy, C 1 -C 6 haloalkoxy, C 1 -C 3 haloalkoxy (C 1 -C 3) haloalkoxy , C 1 -C 6 alkylsulfonyloxy, C 1 -C 6 haloalkylsulfonyloxy, C 1 -C 6 alkylthio, C 1 -C 6 haloalkylthio, C 1 -C 6 alkylsulfinyl, C 1 -C 6 haloalkylsulfinyl, C 1 -C 6 alkylsulfonyl, C 1 -C 6 haloalkylsulfonyl, -C (O) NH 2 or - Represents C (S) NH 2, and when p1, p2, p3 or p4 represents an integer of 2 or more, each Z may be the same as or different from each other;
Further, when two Zs are adjacent, the two adjacent Zs are -CF 2 CF 2 O-, -CF 2 OCF 2- , -OCF 2 O-, -OCF 2 CHFO-, -OCF 2 CF 2 By forming O- or -CH = CHCH = CH-, a 5-membered ring or a 6-membered ring may be formed together with the carbon atom to which each of two Zs is bonded,
R 15 represents C 1 -C 6 alkyl, phenyl or phenyl substituted by (Z) p1 ,
p1 represents an integer of 1 to 5,
p2 represents an integer of 0 to 4,
p3 represents an integer of 0 to 3,
p4 represents an integer of 0 to 2,
p5 represents an integer of 0 or 1,
r represents an integer of 0 to 2;
t represents an integer of 0 or 1. ]
N-substituted phenyl-3-nitrophthalimide or substituted aniline represented by the formula: 請求項１〜請求項４のいずれかに記載の置換ベンズアニリド化合物及びその塩から選ばれる１種又は２種以上を有効成分として含有することを特徴とする有害生物防除剤。   A pest control agent comprising one or more selected from the substituted benzanilide compound according to any one of claims 1 to 4 and a salt thereof as an active ingredient. 請求項１〜請求項４のいずれかに記載の置換ベンズアニリド化合物及びその塩から選ばれる１種又は２種以上を有効成分として含有することを特徴とする農薬。   An agrochemical comprising one or more selected from the substituted benzanilide compound according to any one of claims 1 to 4 and a salt thereof as an active ingredient. 請求項１〜請求項４のいずれかに記載の置換ベンズアニリド化合物及びその塩から選ばれる１種又は２種以上を有効成分として含有することを特徴とする殺虫剤又は殺ダニ剤。   An insecticide or acaricide containing one or more selected from the substituted benzanilide compound according to any one of claims 1 to 4 and a salt thereof as an active ingredient.
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KR20140047079A (en) * 2011-06-24 2014-04-21 다우 아그로사이언시즈 엘엘씨 Pesticidal compositions and processes related thereto
JP2016503060A (en) * 2012-12-19 2016-02-01 ダウ アグロサイエンシィズ エルエルシー Agrochemical compositions and methods relating thereto
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Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011500613A (en) * 2007-10-17 2011-01-06 シンジェンタ パーティシペーションズ アクチェンゲゼルシャフト Insecticidal compounds
KR20140047079A (en) * 2011-06-24 2014-04-21 다우 아그로사이언시즈 엘엘씨 Pesticidal compositions and processes related thereto
JP2014522815A (en) * 2011-06-24 2014-09-08 ダウ アグロサイエンシィズ エルエルシー Pesticide compositions and related processes
JP2016503060A (en) * 2012-12-19 2016-02-01 ダウ アグロサイエンシィズ エルエルシー Agrochemical compositions and methods relating thereto
JP2016508981A (en) * 2012-12-19 2016-03-24 ダウ アグロサイエンシィズ エルエルシー Agrochemical compositions and methods relating thereto
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