JP2005143813A - Human body simulation apparatus for extracorporeal circulation - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a human body simulation apparatus for the extracorporeal circulation improving the operation of an artificial heart-lung machine and trially using the heart-lung machine. <P>SOLUTION: This human body simulation apparatus 1 for the extracorporeal circulation is provided with an artificial human body section 6 connected to the heart-lung machine 2, making artificial blood sent from the heart-lung machine 2 flow therein, sending the inflow artificial blood towards the heart-lung machine 2, and circulating the artificial blood between itself and the heart-lung machine 2. <P>COPYRIGHT: (C)2005,JPO&NCIPI

Description

  The present invention includes a simulated human body part that is connected to an artificial cardiopulmonary device and in which simulated blood is circulated with the cardiopulmonary device, for practice of the artificial cardiopulmonary device, confirmation of the function of the cardiopulmonary device, etc. The present invention relates to a human body simulation device for extracorporeal circulation used in the field.

Conventionally, when the heart of the human body of the operated person is stopped at the time of cardiac surgery or the like, in order to maintain blood circulation in the human body and send oxygen to the human body, a reservoir for storing blood sent from the human body, 2. Description of the Related Art An oxygenator is known that includes a blood pump that delivers blood received from a reservoir, and an oxygenator that performs gas exchange or the like on the blood delivered by the blood pump (see, for example, Patent Document 1).
The operation of such a heart-lung machine is performed by blood pressure (arterial pressure) (approximately 80 to 120 mmHG in the normal state), central venous pressure (CVP) (approximately 5 to 8 mmHG in the normal state), The blood removal resistance from the person's human body and the total blood volume (approximately 4-5 liters in the normal state) in the person's body are displayed on a display device generally used during cardiac surgery, etc. The operator of the heart-lung machine operates an adjustment means such as an adjustment knob that adjusts the amount of blood delivered by the blood pump, while confirming the display of blood pressure, central venous pressure, and blood in the human body. It was done to keep the total amount etc. normal.
JP 2000-245829 A

  However, conventionally, the heart-lung machine is used only in a state where it is attached to the human body in actual heart surgery or the like, and the operation of the heart-lung machine cannot be practiced, and the operator of the heart-lung machine is unskilled. In the case of cardiac surgery, the cardiopulmonary apparatus is not normally operated, and blood pressure, central venous pressure, total blood volume in the human body cannot be maintained normally, or blood sent from the human body is collected There was a risk that the blood in the reservoir would run out.

  In addition, conventionally, an artificial cardiopulmonary apparatus is used only in a state where it is attached to a human body in an actual cardiac surgery or the like, and whether or not blood can be normally circulated by an artificial cardiopulmonary apparatus before being used in a cardiac surgery or the like. Since the cardiopulmonary apparatus could not be used, the function of the heart-lung machine could not be confirmed before the actual cardiac surgery.

  The present invention has been made in view of the above problems, and provides a human body simulation device for extracorporeal circulation that can improve the operation of an oxygenator or can use an oxygenator. The purpose is to do.

  For the above-mentioned purpose, the present invention is connected to an artificial heart-lung machine, the simulated blood sent from the artificial heart-lung machine flows in, and the flowed simulated blood is delivered to the artificial heart-lung machine It is a human body simulation apparatus for extracorporeal circulation provided with a pseudo human body part in which pseudo blood is circulated between the two.

  According to the present invention, an operator who operates the heart-lung machine can operate the heart-lung machine with the human body simulation device connected to the heart-lung machine. In this case, the artificial heart-lung machine can be used before being used for cardiac surgery or the like.

  Further, in the present invention, the simulated blood is provided at the downstream side of the artificial heart-lung machine in the circulation direction of the simulated blood and the upstream side of the simulated human body part, and when the simulated blood is fed into the simulated human body part. Incoming simulated blood pressure changing means for changing the simulated blood pressure may be provided.

  According to the present invention, the simulated blood pressure changing means can change the simulated blood pressure of the simulated blood when it is delivered to the simulated human body part. This simulated blood pressure is used in actual cardiac surgery or the like. Since this corresponds to the blood pressure (arterial pressure), the artificial heart-lung machine was operated with the simulated blood pressure to be transferred to the simulated human body changed, thereby enabling the practice of the artificial heart-lung machine operation. Therefore, for example, even if the simulated blood pressure to be delivered to the simulated human body part is changed by the delivery simulated blood pressure changing means, the simulated blood pressure to be delivered to the simulated human body part by the operation of the oxygenator, particularly the blood pump. Of artificial heart-lung machine corresponding to changes in blood pressure (arterial pressure) in actual cardiac surgery, such as returning to the state before change, or setting the total amount of simulated blood in the simulated human body to a predetermined target value You can practice.

  Further, in the present invention, the simulated blood simulated at the downstream side of the simulated human body part in the simulated blood circulation direction and upstream of the artificial heart-lung machine, and delivered from the simulated human body part. Delivery pseudo blood pressure changing means for changing the blood pressure may be provided.

  According to the present invention, the simulated blood pressure changing means can change the simulated blood pressure delivered from the simulated human body, and the simulated blood pressure changing means can be used for blood removal resistance in actual cardiac surgery or the like. Since it corresponds to changing (the resistance due to the artificial tube connected to the downstream side of the human body and the blood removal resistance is changed due to clogging of the artificial tube, etc.), the simulated blood delivered from the simulated human body part By operating the heart-lung machine with the pressure changed, it was possible to practice the operation of the heart-lung machine. Therefore, for example, even if the simulated blood pressure delivered from the simulated human body part is changed by the delivery simulated blood pressure changing means, the simulated blood pressure delivered from the simulated human body part by the operation of the oxygenator, particularly the blood pump, is changed. Practice the cardiopulmonary apparatus in response to changes in blood removal resistance in actual cardiac surgery, such as returning to the state before the change, or setting the total amount of simulated blood in the simulated human body to a predetermined target value. Can do.

  In the present invention, a simulated total blood volume changing means for changing the total volume of simulated blood that can be accommodated in the simulated human body part may be provided.

  According to the present invention, the total amount of simulated blood in the simulated human body is determined by the operation of the artificial cardiopulmonary apparatus, particularly the blood pump, in a state where the total simulated blood volume in the simulated human body is changed by the simulated blood total volume changing means. It is possible to practice an artificial cardiopulmonary apparatus such as setting a target value. Further, when the total amount of simulated blood in the simulated human body is changed by the simulated total blood volume changing means, the value corresponding to the central venous pressure (CVP) in the actual human body also changes. It is possible to practice an artificial heart-lung machine corresponding to a change in pressure.

  Moreover, in this invention, you may provide the simulated blood bleeding means connected to the said simulated human body part and bleeding the simulated blood from the said simulated human body part.

  According to the present invention, it is possible to practice the operation of an artificial cardiopulmonary apparatus, particularly a blood pump, when bleeding from the human body of the operated person and the total amount of blood in the human body is reduced during cardiac surgery or the like. it can.

  According to the present invention, an operator who operates the heart-lung machine can operate the heart-lung machine in a state where the human body simulation device is connected to the heart-lung machine. In this case, the artificial heart-lung machine can be used before being used for cardiac surgery or the like.

Embodiments of the present invention will be described below with reference to the drawings.
FIG. 1 is an overall view showing a human body simulation apparatus 1 for extracorporeal circulation according to an embodiment of the present invention.
This extracorporeal circulation human body simulation device 1 is connected to an artificial heart lung device 2, and artificial blood that is a liquid such as water circulates in the R direction between the artificial heart lung device 2.

  Here, the cardiopulmonary apparatus 2 to which the extracorporeal circulation human body simulation apparatus 1 according to the embodiment of the present invention is connected is the same as that used in actual cardiac surgery or the like, and is sent from the human body. A reservoir 3 for accumulating blood, a blood pump 4 for delivering blood from the reservoir 3, and an artificial lung 5 for performing gas exchange or the like on the blood delivered by the blood pump 4 are provided. The blood pump 4 is provided with an adjustment knob (not shown), and the flow rate (flow rate per unit time) of blood (pseudo blood in the present invention) to be delivered to the human body (human body simulation apparatus 1 in the present invention). ) Can be adjusted. The flow rate is displayed on a display unit (not shown). Usually, this flow rate is 4 to 5 liters (l) / min.

  An extracorporeal circulation human body simulation device 1 according to an embodiment of the present invention includes a simulated human body portion 6 in which simulated blood circulates between the artificial heart lung device 2 and a downstream side of the artificial heart lung device 2 in the circulation direction of the simulated blood. And a simulated blood pressure changing means 7 provided on the upstream side of the simulated human body portion 6 for changing the simulated blood pressure of the simulated blood when the simulated human body portion 6 is fed, and in the simulated blood circulation direction. A delivery simulated blood pressure changing means 8 provided downstream of the simulated human body 6 and upstream of the cardiopulmonary apparatus 2 for changing the simulated blood pressure of simulated blood when delivered from the simulated human body 6; It is equipped with. The simulated human body part 6 is provided with a simulated total blood volume changing means 9 for changing the total amount of simulated blood that can be accommodated in the simulated human body part 6. A simulated blood bleeding means 10 for bleeding blood is connected.

  A connection between the cardiopulmonary apparatus 2 and the delivery simulated blood pressure changing means 7, a connection between the delivery simulated blood pressure changing means 7 and the simulated human body part 6, a connection between the simulated human body part 6 and the delivery simulated blood pressure changing means 8, Connection between the delivery simulated blood pressure changing means 8 and the heart-lung machine 2 is performed by a tube 11 made of a synthetic resin such as polyethylene.

  The simulated human body portion 6 is a rectangular bag made of a synthetic resin such as polyethylene, and the inside thereof is divided into four simulated blood storage regions 12, and the adjacent simulated blood in these four simulated blood storage regions 12. The simulated blood can freely move between the storage areas 12. In addition, although it is divided into four pseudo blood storage areas 12 here, it may be divided into four or more, or may be divided into less than four. Only the simulated blood storage area 12 may be provided.

  As shown in FIG. 3, in each of these four simulated blood storage areas 12, a weight as the simulated blood total amount changing means 9 can be placed from above, Depending on how many simulated blood storage areas 12 the weight is placed, the total amount of simulated blood that can be stored in the simulated human body 6 is changed (in the simulated blood storage area 12 on which the weight is placed, The simulated blood volume is changed by weight.) In FIG. 3, the number of weights is one, but a maximum of four weights can be placed on each of the four pseudo blood storage areas 12. Various means can be adopted as the simulated blood total amount changing means 9 as long as the capacity of the simulated human body part 6 can be changed, such as a string for binding the simulated human body part 6.

  The amount of simulated blood in the simulated human body portion 6 corresponds to the amount of blood (circulated blood) in the human body of the operated person when actually performing cardiac surgery or the like. Further, the simulated blood pressure delivered from the simulated human body 6 to the outside of the simulated human body changes according to the total amount of simulated blood that can be stored in the simulated human body 6 (the simulated blood that can be stored in the simulated human body 6). The larger the total amount of the more, the smaller the simulated blood pressure delivered from the simulated human body portion 6 to the outside of the simulated human body). For this reason, by changing the total amount of simulated blood that can be delivered into the simulated human body 6 by placing the weight 9 on the simulated human body 6, the human body of the operator when performing a cardiac surgery or the like actually This is also equivalent to changing the central venous pressure at.

  In addition, a simulated blood bleeding tube as a simulated blood bleeding means 10 for bleeding simulated blood from the simulated human body portion 6 is connected to the simulated human body portion 6. The pseudo blood hemorrhage tube 10 is provided with an open / close clamp (not shown). By operating the open / close clamp, the tip of the pseudo blood hemorrhage tube 10 is opened / closed so that pseudo blood bleeding or bleeding stoppage is achieved. To do.

  Although not shown, a value corresponding to the central venous pressure of the human body is displayed on the display.

  One end of the simulated blood pressure changing means 7 for changing the simulated blood pressure of the simulated blood when the simulated human body 6 is delivered is the other end of the tube 11 whose one end is connected to the heart-lung machine 2. The other end portion of the delivery simulated blood pressure changing means 7 is connected to the other end portion of the tube 11 whose one end portion is coupled to the simulated human body portion 6. The delivery pseudo blood pressure changing means 7 is provided with four branch pipes 14, 15, 16, and 17 that branch into four from the middle, and the four branch pipes 14, 15, 16, and 17 join downstream. doing. The four branch pipes 14, 15, 16, and 17 have pseudo blood passages having different diameters.

  Opening and closing clamps 18 and 19 are attached to each of the four branch pipes 14, 15, 16, and 17. By operating each of the opening and closing clamps 18 and 19, the four branch pipes 14, 15, 16, and 17 are attached. Each simulated blood passage is opened and closed. Therefore, depending on the number of closing clamps 18, 19 attached to the four branch pipes 14, 15, 16, and 17, and the opening / closing clamps 18, 19, the simulated blood pressure changing means 7 is changed in unit time. The flow rate of the simulated blood passing therethrough is changed, whereby the simulated blood pressure of the simulated blood when being fed into the simulated human body part 6 can be changed. This change in pseudo blood pressure corresponds to a change in blood pressure (arterial pressure) in actual cardiac surgery or the like. In addition, in the state where all of the four branch pipes 14, 15, 16, 17 are open, the simulated blood pressure of the pseudo blood when being fed into the simulated human body part 6 is the highest, and the branch pipes 14, 15, 16, This pseudo blood pressure decreases as the number of closing 17 increases.

  Further, as the open / close clamps 17 and 18, an engagement portion 19 having an acute-angled tip as shown in FIG. 2A is arranged at any position in the engagement receiving portion 20 provided in multiple stages in a saw blade shape. 2 (b) as well as a multi-stage open / close clamp (multi-stage flow regulator) 17 that can change the flow rate of the pseudo blood passing through the passage of the branch pipe 14 depending on whether it is engaged with It is possible to use both of the on-off type open / close clamp 18 that can be switched only whether or not the engagement portion 19 having an acute angle is engaged with the single engagement receiving portion 21.

  In addition, the delivery simulated blood pressure changing means 7 is not limited to the four branch pipes 14, 15, 16, and 17, but can be used in various ways, for example, using two branch pipes or eight branch pipes. Further, instead of using a branch pipe, a dial-type (analog type) adjustment valve that adjusts the opening area of one pipe may be used to change the flow rate of pseudo blood passing through the analog type.

  Although not shown, simulated blood pressure of pseudo blood (corresponding to blood pressure of the human body) when being fed into the simulated human body 6 is displayed on the display.

  One end of the delivery simulated blood pressure changing means 8 for changing the simulated blood pressure of the simulated blood delivered from the simulated human body 6 is connected to the other end of the tube 11 whose one end is connected to the simulated human body 6. The other end portion of the delivery simulated blood pressure changing means 8 is connected to the other end portion of the tube 11 connected to the oxygenator 2 at one end portion.

As the delivery simulated blood pressure changing means 8, in this embodiment, the same member as the delivery simulated blood pressure changing means 7 is used.
That is, the delivery simulated blood pressure changing means 8 includes four branch pipes 22, 23, 24, and 25 that branch into four from the middle, and the four branch pipes 22, 23, 24, and 25 are arranged on the downstream side. Have joined. The four branch pipes 22, 23, 24, and 25 have pseudo blood passages having different diameters.

  Open / close clamps 26 and 27 are attached to each of the four branch pipes 22, 23, 24, and 25. By operating each of the open / close clamps 26 and 27, the four branch pipes 22, 23, 24, and 25 are connected. Each simulated blood passage is opened and closed. Therefore, depending on the number of closing clamps 26, 27 attached to the four branch pipes 22, 23, 24, 25, respectively, and the opening / closing clamps 26, 27, the simulated blood pressure changing means 8 passes through the delivery time per unit time. The flow rate of the simulated blood changes, so that the simulated blood pressure of the simulated blood when the simulated blood is delivered from the simulated human body 6 can be changed. This change in the pseudo blood pressure corresponds to a change in the value of blood removal resistance outside the human body in actual cardiac surgery or the like. In the state where all of the four branch pipes 22, 23, 24, 25 are open, the value corresponding to the blood removal resistance value is the lowest, and as the number of closing the branch pipes 22, 23, 24, 25 increases. This value becomes larger.

  Further, as the open / close clamp, the flow rate of the pseudo blood passing through the passage of the branch tube 22 can be changed depending on which position in the engagement receiving portion 29 provided in multiple stages the engagement portion 28 is engaged with. In addition to the multistage open / close clamp (multistage flow rate adjusting tool) 26, it is possible to use both an on / off open / close clamp 27 that can switch only whether or not the engaging portion 28 is engaged with the engagement receiving portion 30. . As the multi-stage open / close clamp 26 and the on / off open / close clamp 27, those similar to those shown in FIG. 2 can be employed.

The delivery simulated blood pressure changing means 8 is not limited to the four branch pipes 22, 23, 24, 25, but can be variously used, for example, two branch pipes or eight branch pipes. Further, instead of using a branch pipe, the flow rate of the pseudo blood passing in an analog manner may be changed by a dial type (analog type) regulating valve.
Although not shown, the value corresponding to the blood removal resistance is displayed on the display.

1 is an overall view showing a human body simulation device for extracorporeal circulation according to an embodiment of the present invention. It is a figure which shows the open / close clamp used with the human body simulation apparatus for extracorporeal circulation by embodiment of this invention. It is a figure which shows the simulated blood total amount change means used with the human body simulation apparatus for extracorporeal circulation by embodiment of this invention.

Explanation of symbols

DESCRIPTION OF SYMBOLS 1 ... Human body simulation apparatus for extracorporeal circulation, 2 ... Artificial heart-lung machine, 6 ... Simulated human body part, 7 ... Delivery simulated blood pressure change means, 8 ... Delivery simulated blood pressure change means, 9 ... Simulated blood Total amount change means, 10 ... Simulated blood bleeding means

Claims (5)

The simulated blood is connected to the heart-lung machine, the simulated blood sent from the heart-lung machine flows in, and the simulated blood that flows in is sent to the heart-lung machine, and the simulated blood is circulated between the heart-lung machine A human body simulation device for extracorporeal circulation provided with a simulated human body. The pseudo blood pressure of the simulated blood is changed to the downstream side of the artificial heart-lung machine in the direction of the simulated blood circulation and upstream of the simulated human body part when the simulated blood is sent to the simulated human body part. The human body simulation apparatus for extracorporeal circulation according to claim 1, further comprising a delivery pseudo blood pressure changing unit. Delivery that is provided on the downstream side of the simulated human body part in the circulation direction of the simulated blood and upstream of the oxygenator, and changes the simulated blood pressure of the simulated blood when delivered from the simulated human body part. The human body simulation device for extracorporeal circulation according to claim 1 or 2, further comprising pseudo blood pressure changing means. The human body simulation device for extracorporeal circulation according to any one of claims 1 to 3, further comprising pseudo blood total amount changing means for changing the total amount of pseudo blood that can be accommodated in the pseudo human body part. The human body simulation apparatus for extracorporeal circulation according to any one of claims 1 to 4, further comprising pseudo blood bleeding means connected to the pseudo human body part for bleeding pseudo blood from the pseudo human body part.

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