JP2005053883A - Gel-form bathing agent used by application - Google Patents
Gel-form bathing agent used by application Download PDFInfo
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- JP2005053883A JP2005053883A JP2003316046A JP2003316046A JP2005053883A JP 2005053883 A JP2005053883 A JP 2005053883A JP 2003316046 A JP2003316046 A JP 2003316046A JP 2003316046 A JP2003316046 A JP 2003316046A JP 2005053883 A JP2005053883 A JP 2005053883A
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Abstract
Description
本発明は、浴湯の中でほとんど溶解・拡散せずに、皮膚にゲル状膜として付着して身体に作用する、体に塗って使うゲル状入浴剤に関する。 The present invention relates to a gel-like bathing agent applied to the body that adheres to the skin as a gel-like film and acts on the body with almost no dissolution / diffusion in bath water.
従来の入浴剤は、粉末・液状・固体等様々な様相を呈しているが、その性状は浴槽内の湯に、溶解または拡散させて使用する事を目的としていた為、含有されている有効成分がきわめて低濃度に希釈されてしまい、残り湯も入浴剤の溶解または拡散により汚れてしまうという欠点があった。 Conventional bathing agents have various aspects such as powder, liquid, solid, etc., but their properties were intended to be used by dissolving or diffusing in hot water in the bath. However, the remaining hot water is contaminated by dissolution or diffusion of the bath agent.
さらに、肩こり・腰痛・偏頭痛・腱鞘炎・リュウマチ・ダイエット等に効果がある温熱発汗作用を得るための刺激剤(塩、トウガラシエキス,ショウキョウエキス,センブリエキス,メントール,ユーカリエキス,サリチル酸等)を効果が期待出来る濃度まで配合すると、浴湯全体にこれらが溶解・拡散する為、陰部粘膜や皮膚の弱い部分・傷や肌トラブルのある部分を特に刺激し、ヒリヒリ感や炎症を引き起こす危険性があった。 In addition, stimulants (salt, pepper extract, pepper extract, sembly extract, menthol, eucalyptus extract, salicylic acid, etc.) to obtain thermal sweating action effective for stiff shoulders, low back pain, migraine, tendonitis, rheumatism, diet, etc. When blended to a concentration that can be expected to have an effect, these will dissolve and diffuse throughout the bath water, which may irritate the genital mucosa, weak areas of the skin, areas with scars and skin troubles, and may cause irritation or inflammation. there were.
そこで本発明は、上記のような従来の入浴剤の問題点を解決し、入浴剤に配合した薬効成分が浴湯で希釈されず、ほぼ配合されたままの濃度で身体に作用することと、温熱発汗作用を得るための刺激剤(塩、トウガラシエキス,ショウキョウエキス,センブリエキス,メントール,ユーカリエキス,サリチル酸等)を高い効果が期待出来る濃度まで配合しても、肌にヒリヒリ感や炎症を引き起こす危険性がないこと、しかも残り湯が汚れない、という入浴剤の形状を提供することを目的としている。 Therefore, the present invention solves the problems of the conventional bathing agents as described above, and the medicinal ingredients blended in the bathing agent are not diluted with bath water, but act on the body at a concentration almost blended, Even if you add a stimulant (salt, pepper extract, ginger extract, assembly extract, menthol, eucalyptus extract, salicylic acid, etc.) to obtain a hot sweating effect, even if you combine it to a concentration where you can expect high effects, it will irritate and irritate the skin The object of the present invention is to provide a bathing agent form that has no danger of causing the contamination and that the remaining hot water does not become dirty.
本発明者は、入浴剤は、浴湯に溶解もしくは拡散させるという概念を根本から見直し、増粘剤を使ってゲル状物とし、その使用方法も身体の部分または全体に塗り、そのまま浴湯に浸かる、もしくは蒸しタオル等で温め、その後、浴槽外で洗い流せば上記課題を解決できることを見い出し本発明に至った。 The inventor has fundamentally reviewed the concept that bathing agents are dissolved or diffused in bath water, and used a thickener as a gel-like material. It has been found that the above-mentioned problems can be solved by soaking or warming with a steam towel etc. and then washing out of the bathtub.
本発明において、増粘剤を用いたゲル状入浴剤とは、クリーム状やマヨネーズ状といった粘度を有するゲル状物に属する製剤を意味し、身体に容易に塗布することができ、塗布後、身体が十分温まる時間(2〜10分程度)浴湯中で、完全溶解せず、シャワー・手拭等で容易に洗い流せるものであることを意味する。 In the present invention, the gel bath agent using a thickener means a preparation belonging to a gel-like material having a viscosity such as cream or mayonnaise, and can be easily applied to the body. Means that it can be easily washed away by showering, hand-wiping or the like without being completely dissolved in the bath water for a sufficiently warmed time (about 2 to 10 minutes).
このゲル状物は、浴湯に対して難溶性かつ親水性の性質を持つので、塗布した部分のみが、薬効成分を含有したゲル状の親水性の膜となる。浴湯に浸かるか、蒸しタオルで温めると、この膜で覆われた部分は、この膜に含まれる成分組成と同じ成分組成を持つ浴湯に浸かったことと同様の効果が得られ、その後、浴槽外で洗い流すか、拭きとれば浴湯も汚れない。 Since this gel-like material has a property of being sparingly soluble in bath water and hydrophilic, only the applied portion becomes a gel-like hydrophilic film containing a medicinal component. When immersed in bath water or warmed with a steamed towel, the portion covered with this film has the same effect as being immersed in bath water having the same component composition as that contained in this film, and then If you wash it out of the bathtub or wipe it off, the bath will not get dirty.
本発明において、増粘剤を用いたゲル状入浴剤における増粘剤とは、水または水溶成分(薬効成分・その他の各種成分や乳化剤を含有した水溶液)を増粘するものである。具体的には、高分子ゲル化剤(ヒドロキシエチルセルロース・ヒドロキシプロピルメチルセルロース・セチルメチルセルロース等)・ガム類(キサンタンガム・クゥアーガム・ラボールガム等)・海藻類(アルギン酸ナトリウム等)・ゲル化剤(ポリアクリル酸ナトリウム・カルボマー等)がある。本発明においては、高分子ゲル化剤(ヒドロキシエチルセルロース・ヒドロキシプロピルメチルセルロース・セチルメチルセルロース等)が好ましい。 In the present invention, the thickener in the gel bathing agent using a thickener thickens water or a water-soluble component (medicinal component, other various components and an aqueous solution containing an emulsifier). Specifically, polymer gelling agents (hydroxyethylcellulose, hydroxypropylmethylcellulose, cetylmethylcellulose, etc.), gums (xanthan gum, guar gum, laval gum, etc.), seaweeds (sodium alginate, etc.), gelling agents (sodium polyacrylate)・ Carbomer etc.). In the present invention, polymer gelling agents (hydroxyethylcellulose, hydroxypropylmethylcellulose, cetylmethylcellulose, etc.) are preferable.
さらに、上記のような高分子ゲル化剤にガム類(キサンタンガム・クゥアーガム・ラボールガム等)を加えて製剤すれば、ゲル状物の粘度・さらなる難溶性の付与等の調整が可能である。また、これらの増粘剤は、化粧品、医薬部外品、医薬品に広く使用されているが、ゲル状物とした入浴剤を製剤し、その使用方法も身体の部分または全体に塗って、そのまま浴湯に浸かるか、蒸しタオル等で温めるという目的で、入浴剤組成物に配合することは未だ知られていない。 Furthermore, if a gum (xanthan gum, guar gum, labour gum, etc.) is added to the polymer gelling agent as described above, it is possible to adjust the viscosity of the gel-like product and impart further poor solubility. These thickeners are widely used in cosmetics, quasi-drugs, and pharmaceuticals, but they are formulated as a gel-like bathing agent, and the method of use is also applied to the entire body part or the entire body. It has not been known yet to be blended into a bath composition for the purpose of soaking in bath water or warming with a steam towel.
上記のような、本発明の塗って使うゲル状入浴剤に配合される増粘剤(高分子ゲル化剤または、高分子ゲル化剤とガム類の総量)の含有量は、0.1〜5重量%さらには、1〜3.5重量%が良い。これよりも配合量が少ないと浴湯に溶解しやすくなり、また配合量が多いとダマになり、身体に塗布しにくくなる。 The content of the thickening agent (the polymer gelling agent or the total amount of the polymer gelling agent and gums) blended in the gelled bathing agent used in the present invention as described above is 0.1 to 5% by weight or 1 to 3.5% by weight is preferable. If the blending amount is less than this, it will be easy to dissolve in the bath water, and if the blending amount is large, it will become tedious and difficult to apply to the body.
本発明における入浴剤組成物には、上記増粘剤の必須成分と温熱発汗作用を得るための刺激剤を始めとした各種薬効成分以外に、通常入浴剤組成物に用いられる各種成分、例えば、無機塩類・香料・着色剤・有機酸・界面活性剤・粉体・酸化防止剤・油成分・抗菌剤等を配合することができる。 In the bath agent composition of the present invention, in addition to the essential components of the thickener and various medicinal components including a stimulant for obtaining a thermal sweating action, various components that are usually used in a bath agent composition, for example, Inorganic salts, fragrances, colorants, organic acids, surfactants, powders, antioxidants, oil components, antibacterial agents, and the like can be blended.
本発明の塗って使うゲル状入浴剤は、水・上記薬効成分やその他の各種成分(どちらも油溶成分は、あらかじめ乳化しておく)に上記の増粘剤を加え、公知の方法により、例えばホモミキサー等で撹拌することで簡単に製造することができる。詳しくは、水に上記の増粘剤を加え、ホモミキサー等で撹拌してゲル状物とし、水溶性の上記薬効成分やその他の各種成分はそのまま加え、油溶性の上記薬効成分やその他の各種成分は、乳化してから加えて製剤としたり、水に上記薬効成分やその他の各種成分(油溶成分は、あら分は、あらかじめ乳化しておく)を加え水溶成分とし、上記の増粘剤を加え、ホモミキサー等で撹拌してゲル状にして製剤とする等様々な公知の方法がある。 The gel bathing agent used in the present invention is the above-mentioned thickener added to water, the above-mentioned medicinal components and other various components (both oil-soluble components are pre-emulsified), and by a known method, For example, it can be easily produced by stirring with a homomixer or the like. Specifically, the above thickener is added to water, stirred with a homomixer or the like to form a gel, the water-soluble medicinal ingredients and other various ingredients are added as they are, and the oil-soluble medicinal ingredients and other various ingredients. Ingredients are added after emulsification to form a preparation, and the above-mentioned medicinal ingredients and other various ingredients (oil-soluble ingredients are pre-emulsified in advance) are added to water to make water-soluble ingredients. In addition, there are various known methods such as adding a mixture into a gel by stirring with a homomixer or the like.
以下に実施例において本発明を具体的に説明するが、これらの実施例に限定されるものではない。
(1)浴湯に対する難溶性の確認試験
下記表1記載の処方からなる塗って入るゲル状入浴剤を製剤し、被験者のすねに適量を塗付し、40℃の浴湯に10分間浸して、完全溶解していない状態であることを目視及び指での接触で確認した。完全溶解していない状態とは、十分にゲル状の、ぬるぬるが皮膚にのこっている半溶解の状態である。EXAMPLES The present invention will be specifically described below with reference to examples, but the present invention is not limited to these examples.
(1) Confirmation test for sparing solubility in bath water Prepare a gel-like bath agent to be applied with the formulation shown in Table 1 below, apply an appropriate amount to the subject's shin, and soak in bath water at 40 ° C for 10 minutes. It was confirmed by visual inspection and finger contact that the sample was not completely dissolved. The state in which it is not completely dissolved is a sufficiently gel-like, semi-dissolved state in which the slimy remains on the skin.
使用原料の商品明並びに会社名は、以下のとおりである。
ヒドロキシエチルセルロース、HEC SE500 ダイセル
トウガラシチンキ、 トウガラシチンキ 丸善製薬
海塩、 博多の塩 九州ソルト
Hydroxyethyl cellulose, HEC SE500 Daicel pepper tincture, pepper tincture Maruzen Pharmaceutical Sea Salt, Hakata Salt Kyushu Salt
表2中完全溶解は×、少し残っているは△、半溶解は○、ほとんと溶解していないは◎として示した。 In Table 2, complete dissolution is indicated as x, a little remaining is indicated as Δ, semi-dissolution is indicated as ○, and almost no dissolution is indicated as ◎.
さらに実施例において本発明を具体的に説明するが、これらの実施例に限定されるものではない。
(2)塩、トウガラシチンキを用いた皮膚刺激試験
下記表3記載の処方からなる塗って使うゲル状入浴剤を製剤し、50名の被験者の腹部に適量を塗付し、41℃の浴湯に7分間浸り、ひりひり感や発赤・炎症等が皮膚に生じるかどうかを判定した試験。(判定員 薬剤師 加藤宏一)Further, the present invention will be specifically described in Examples, but the present invention is not limited to these Examples.
(2) Skin irritation test using salt and red pepper tincture A gel-like bathing agent to be applied with the formulation described in Table 3 below is formulated, and an appropriate amount is applied to the abdomen of 50 subjects, and the bath is 41 ° C. A test to determine whether irritation, redness or inflammation occurs in the skin for 7 minutes. (Judge, Pharmacist Koichi Kato)
使用原料の商品明並びに会社名は、以下のとおりである。
ヒドロキシエチルセルロース、HEC SE500 ダイセル
トウガラシチンキ、 トウガラシチンキ 丸善製薬
海塩、 博多の塩 九州ソルト
Hydroxyethyl cellulose, HEC SE500 Daicel pepper tincture, pepper tincture Maruzen Pharmaceutical Sea Salt, Hakata Salt Kyushu Salt
表4中被験者50名に全く問題がみられない場合、なしとして示した。 In Table 4, when no problem was found in 50 subjects, it was indicated as none.
さらに実施例において本発明を具体的に説明するが、これらの実施例に限定されるものではない。
(3)塩、トウガラシチンキを用いた疼痛緩和試験
下記表5記載の処方からなる塗って使うゲル状入浴剤を製剤し、肩こりを持つ被験者50名の疼痛部分に適量を塗付し、42℃の浴湯に6分間浸り、肩こりの緩和を判定した試験。判定は、入浴1時間後に、被験者の自主申告と判定員 薬剤師加藤宏一の客観視によるものとする。Further, the present invention will be specifically described in Examples, but the present invention is not limited to these Examples.
(3) Pain alleviation test using salt and chili tincture A gel-like bathing agent to be applied consisting of the formulation shown in Table 5 below is formulated, and an appropriate amount is applied to the pain part of 50 subjects with stiff shoulders at 42 ° C. The test which judged the relaxation of the stiff shoulder by soaking for 6 minutes. Judgment is based on the subject's voluntary declaration and objective judgment by the judge pharmacist Koichi Kato after 1 hour of bathing.
使用原料の商品明並びに会社名は、以下のとおりである。
ヒドロキシエチルセルロース、HEC SE500 ダイセル
トウガラシチンキ、 トウガラシチンキ 丸善製薬
海塩、 博多の塩 九州ソルト
Hydroxyethyl cellulose, HEC SE500 Daicel pepper tincture, pepper tincture Maruzen Pharmaceutical Sea Salt, Hakata Salt Kyushu Salt
表6中緩和の程度を人数で示した、また、より正確な結果を得るため、気分を高揚させると考えられる香料は処方中より取り除いた。 In Table 6, the degree of relaxation was shown by the number of people, and in order to obtain a more accurate result, the perfume that was thought to enhance the mood was removed from the formulation.
さらに実施例において本発明を具体的に説明するが、これらの実施例に限定されるものではない。
(4)塩、トウガラシチンキ、メントールを用いた腹部ダイエット試験
下記表7記載の処方からなる塗って使うゲル状入浴剤を製剤し、腹部ダイエット希望を有する被験者53名の下腹部分に適量を塗付し、42℃の浴湯に6分間浸り、これを1週間(1日1回、7日間)続け、その間の食時は、通常どおりとして腹部ダイエット効果を判定した試験。Further, the present invention will be specifically described in Examples, but the present invention is not limited to these Examples.
(4) Abdominal diet test using salt, pepper tincture, and menthol A gel-like bathing agent to be applied consisting of the prescription in Table 7 below is formulated, and an appropriate amount is applied to the lower abdomen of 53 subjects who have abdominal diet desires. Then, immersed in 42 ° C. bath water for 6 minutes, continued for 1 week (once a day for 7 days), and during that time, the test of judging the abdominal diet effect as usual.
使用原料の商品明並びに会社名は、以下のとおりである。
ヒドロキシエチルセルロース、HEC SE500 ダイセル
トウガラシチンキ、 トウガラシチンキ 丸善製薬
海塩、 博多の塩 九州ソルト
Hydroxyethyl cellulose, HEC SE500 Daicel pepper, tincture Maruzen sea salt, Hakata salt Kyushu salt
結果は、試験開始前の下腹部回り最大部から、終了後の下腹部回り最大部を引いた値として示した。 The result was shown as a value obtained by subtracting the maximum part around the lower abdomen after the end from the maximum part around the lower abdomen before the start of the test.
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JP2003316046A JP2005053883A (en) | 2003-08-06 | 2003-08-06 | Gel-form bathing agent used by application |
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JP2003316046A JP2005053883A (en) | 2003-08-06 | 2003-08-06 | Gel-form bathing agent used by application |
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
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JP2007015973A (en) * | 2005-07-07 | 2007-01-25 | Nippon Kenko Kagaku Kenkyu Center:Kk | Film preparation for bathing |
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
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JP2007015973A (en) * | 2005-07-07 | 2007-01-25 | Nippon Kenko Kagaku Kenkyu Center:Kk | Film preparation for bathing |
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