JP2002277476A - Automatic analysis apparatus - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide an automatic analysis apparatus for improving safety in use for preventing an operator from touching a specimen or a dispensing mechanism since a large lid for covering the entire apparatus is in use and the entire equipment including the section of a container that is not used is exposed when the lid is opened. SOLUTION: A depth dimension t1 and a width dimension w1 of an enclosure 40 are composed compactly, an entrance door may be opened when the apparatus is to be carried into a clinical inspection room or the like, and much installation space is not required, so that the environment in the clinical inspection room is improved, the mental health of an operator or the like who works at the clinical inspection room is improved, and operation may be made based on an instruction that is displayed on an LCD 52 having a touch panel for I/O and display also regarding the operation of the apparatus for simplifying operation, and mistaking an appropriate specimen for a wrong one can be prevented since one may concentrate on the handling of the specimen.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to an automatic analyzer,
In particular, the present invention relates to an automatic analyzer that is suitable for use in biochemical tests and immunological tests by rotating a row of reaction vessels across the optical path of a photometer.

[0002]

2. Description of the Related Art A conventional automatic analyzer, as described in, for example, Japanese Patent Publication No. 59-22905, requires a single dispensing mechanism for one reagent and reduces it to only two dispensing mechanisms. This was effective in that the mechanism was simplified.
In addition, as described in JP-A-6-88828, the reaction vessel is increased for the purpose of increasing the processing capacity so that all the reactions can be performed in parallel at the same time and preventing the occurrence of contamination between reagents. Double or triple, each reaction vessel row is made independent, and the reaction vessels are washed for each process of the reaction to enable continuous processing. One example of these is shown in Design Registration No. 784418.

[0003]

In the conventional apparatus, a large lid is used to cover the entire apparatus. When the lid is opened, all equipment including the unused container is exposed. Was gone. In view of the above, an object of the present invention is to provide an automatic analyzer with improved safety in use, which does not involve an operator touching a sample or a dispensing mechanism.

[0004]

One of the solutions to the above-mentioned problems is to have a sample holding means, a reagent holding means, a dispensing means, and an analyzing means, and to cause a sample and a reagent to react in a reaction vessel. In the automatic analyzer for analyzing the reacted reaction solution by the analysis means, the sample holding means and the reagent holding means are arranged obliquely on the front side of the housing, and the reaction container is further provided behind the sample holding means and the reagent holding means. And that it is arranged at an intermediate position between the sample holding means and the reagent holding means. Another solution to the above problem is that a lid is configured to independently cover the sample holding means, the reagent holding means, and the dispensing means.

[0005] Further, another solution to the above-mentioned problem is as follows.
An input / output device for an automatic analyzer having a display means for displaying information on the analyzer is arranged on the front side of the reagent holding means.

[0006]

In the opening of the top plate 41, a lid for a reaction container covering the reaction container, a lid for the sample container covering the sample container and a lid for the reagent container covering the reagent container, a sample dispenser and a reagent dispenser are provided. And the lid for the dispensing mechanism can be configured independently of each other, and all the parts including the parts not used when the lid is opened can be configured. As compared with the conventional large lid that covers the entire apparatus, which exposes the device, the part that does not need to be exposed is always covered with the lid, so that the operator does not touch the sample or touch the dispensing mechanism. Further, if the lid for the dispensing mechanism is made transparent, the operator can confirm the movement of the dispensing mechanism from outside, so that the safety during use is further improved.

[0007]

DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS One embodiment of the automatic analyzer according to the present invention will be described below with reference to the accompanying drawings.

FIG. 1 is an external view of an automatic analyzer according to one embodiment of the present invention. FIG. 2 is a principle diagram of a main part of the automatic analyzer in FIG. 1, and FIG. 3 is an exploded view of the automatic analyzer in FIG.

First, referring to FIG. 2, the principle of the main part of the automatic analyzer according to the present invention will be described. In this apparatus, a plurality of translucent rectangular plastic reaction vessels 2 are held on a rotary reaction disc 3. Also, a plurality of reagent containers 21 are arranged on a rotary type reagent disk 22. Further, a plurality of sample containers 11 for a sample to be measured and a plurality of standard samples are set on a rotating sample disk 12.

The sample container 11 at a fixed position on the sample disk 12
A sample sampling mechanism 14 that draws a predetermined amount of each sample liquid based on the input sample information into the nozzle 13 held by the sample movable arm and discharges the sample into the reaction vessel 2 at a fixed position on the reaction disk 3 (Hereinafter referred to as a sample dispenser) and a micro-scilling mechanism 15. Also, a single reagent pipetting mechanism 24 (hereinafter referred to as a reagent dispenser),
The scilling mechanism 17 is rotated based on the input sample information, and a predetermined amount based on the input information is supplied from the reagent bottle at the reagent suction position on the reagent disk 22 whose stop position is controlled into the reagent nozzle 23 held on the movable arm. Is sucked and added to the reaction container 2 at the reagent discharge position on the reaction table 3. The stirring position of the reaction solution accommodated in the reaction container 2 by the stirring mechanism 4 is matched with the reagent discharge position on the reaction disk 3.

In addition, a high-speed multi-wavelength photometer 5 for measuring the absorbance of each reaction vessel 2 crossing the optical axis at a predetermined wavelength based on input information when the reaction disk 3 rotates, and a reaction vessel 2 after the measurement is completed. A cleaning nozzle mechanism 6 for cleaning, a supply / drain pump mechanism 16 for cleaning, an LG amplifier 18, an A / D converter 19, a computer 50 for operation control and data processing of each mechanism, a printer 51 for output, and a touch panel for input / output and display. LCD 52, disk mechanism 53 for program, measurement condition and data memory, circulating constant temperature water tank 54 for maintaining each reaction vessel 2 on reaction disk 3 at a constant temperature, interface 55 connecting computer 50 to each mechanism system, etc. Be composed.

Next, a specific arrangement of the automatic analyzer according to the present invention will be described. 1 and 3,
Each of the devices described with reference to FIG. 2 is partially incorporated in the housing 40 and partially exposed on the upper surface of the housing 40. On the upper surface of the housing 40, the sample disk 12 is on the left side of the operator side (hereinafter, referred to as the near side), the reagent disk 22 is on the right side thereof, and the rear side of the reagent disk 22 from the operator side (hereinafter, the rear side). Output printer 5
1 is arranged.

The diameter of the reagent disk 22 is made larger than that of the sample disk 12, and the reagent disk 22 is arranged such that the center of the sample disk 12 is closer to the front than the center of the reagent disk 22. The reaction disk 3 is arranged behind the sample disk 12 such that the center of the reaction disk 3 is closer to the reagent disk 22 than the center of the sample disk 12. That is, the sample container 11 is arranged in front of the analyzer that is the reaction container 2, and the reagent container 21 is arranged in the lateral direction of the sample container 11 and deeper than the sample container 11. Although the details will be described later, the sample dispenser 14 moves the reaction disc 3 within the rotation range of the arm 13 of the sample dispenser 14.
And the sample disk 12 are accommodated.
The left side dimension when viewed from the front side of the upper surface of the housing 40 is shorter than the length dimension of the fourth arm 13. Further, the reagent dispenser 24 is arranged behind the reagent disk 22 so that the reaction disk 3 and the reagent disk 22 fall within the rotation range of the arm 23 of the reagent dispenser 24.

Thus, each of the disks 3, 1
2 and 22 are arranged close to each other, and the sample dispenser 14 and the reagent dispenser 24 disposed deeper than the sample disc 12 and the reagent disc 22 are used as reagent dispensers. It will be arranged diagonally as a deeper back side.
As shown in the figure, the sample container and the reagent container are arranged obliquely with the reagent container at a deeper depth.
As a result, the size of the apparatus can be reduced in the lateral direction, the entire apparatus can be made compact, and the installation area of the apparatus can be reduced.

Further, a top plate 41 having a smooth surface is provided on the upper surface of the housing 40 and is separable from the housing 40. On the top plate 41, the reaction disk 3, the sample disk 12, the reagent disk 22, the sample dispenser 14, the reagent dispenser 24, and the output printer 51 are respectively exposed at portions corresponding to respective portions so as to be exposed. An opening is configured. Since the top plate 41 has a smooth surface, the upper surface of the apparatus becomes a smooth surface when mounted on the housing 40, and is easy to clean.

The housing 40 is located near the reagent disk 22.
LCD with touch panel for input / output and display in front of
52, and the safety indicator 42 is arranged near the sample disk 12 and on the near side. On the left side of the sample disk 12 of the top plate 41, a transfer line groove 45 is arranged. A secondary power switch 43 is disposed on a vertical surface on the near side of the housing 40 of the top plate 41. Although not shown, a primary power switch is disposed on a vertical surface of the top plate 41 on the rear side of the housing 40.

The transfer line groove 45 is continuous with a groove 46a arranged on the sample disk cover 10 described later, and is arranged along the trajectory of the rotating mechanism of the sample dispenser 14. When used by connecting another device, for example, a centrifuge, to the left side when viewed from the front side of the sample, the sample is moved from the other device to the sample disk 12 or from the sample disk 12 to the other device. Can be performed continuously.

At the opening of the top plate 41, a reaction disk cover 1 covering the reaction disk 3, a sample disk cover 10 covering the sample disk 12, a reagent disk cover 20 covering the reagent disk 22, Dispenser 14 and reagent dispenser 2
4 and a transparent dispensing mechanism lid 30 for covering the same.
Each of the disc lids 1, 10, and 20, and the dispensing mechanism lid 3
Because each device is independently configured, all parts including the unused parts are exposed when the lid is opened. Compared with the conventional large lid that covers the entire device, the parts that do not need to be exposed are always covered. As the operator does not touch the sample or the dispensing mechanism, the safety during use can be improved. Further, since the dispensing mechanism lid 30 is transparent, the operator can confirm the movement of the dispensing mechanism from outside, so that the safety during use can be further improved.

In addition, each of the lids 1, 10, 20, 3
0, are independently configured, so that each of the above lids 1, 1
0, 20, 30, may be the minimum required area, and as a result,
The productivity of the lid is improved, and the upper surface of the device can be formed compact. Although the dispensing mechanism lid 30 has been described as being transparent in this embodiment, the transmittance is such that the inside of the dispensing mechanism lid 30 can be visually confirmed.
For example, a material such as translucent material may be used.

A dispensing mechanism base 44 is provided in the opening of the top plate 41 where the sample dispenser 14 and the reagent dispenser 24 are exposed.
a, b, and c. In the event of a failure, the lids 1, 10, and 20, the dispensing mechanism lid 30, and the dispensing mechanism bases 44a, b, and c are removed from each of the above-described disks to remove the sample. The top plate 41 can be removed from the housing 40 without removing the arm of the injector 14 and the arm of the reagent dispenser 24,
Since each device can be easily exposed, the system for repair can be easily prepared.

In this embodiment, the dispensing mechanism base 44
Has been described as being composed of three members, but the opening of the top plate 41 on which the dispensing mechanism base 44 is installed may be exposed, and at least the dispensing mechanism base 4
4 may be composed of two members, or the dispensing mechanism base 44 may be composed of a single member, and a notch may be formed in a column between the sample dispenser 14 and the reagent dispenser 24. You may comprise.

FIG. 4 is a plan view of the automatic analyzer shown in FIG. In the figure, the sample disk 12 of the top plate 41
On the near side, a 30 mm protruding portion h1 of the sample disk 12 is formed concentrically on the near side of the apparatus while slightly leaving the smooth surface of the housing 40 slightly on the left and right. The protrusion h
1, a safety indicator 42, which is a display unit that indicates the movable state of the sample disk 12, is provided. The safety indicator 42 is off when the sample disk 12 is stationary or when the arm of the sample dispenser 14 is stopped on the reaction disk 3 side. Is green, the green LED is lit. Thus, when the operator approaches the apparatus to set a sample on the sample disk 12, the operator is notified that the apparatus is in a movable state, and the operator is alerted. In addition, since the near side of the sample disk 12 protrudes, the operator can easily recognize the position of the sample disk 12, so that an error in setting can be prevented.

In the present embodiment, the LED of the safety indicator 42 is described as being green, but the present invention is not limited to this and may be red, blue or the like. Further, the protrusion h1 of the top plate 41 only needs to have such a size that the protrusion can be visually recognized, and the smooth surface of the housing 40 may be left on the left and right of the protrusion h1. The portion h1 may be in the range of 10 mm to 50 mm. Further, the protrusion h1 and the safety indicator 42 may be located near the sample disk 12, and may be arranged, for example, on the side of the sample disk 12.

On the rear side of the reaction disk cover 1,
A slit hole 8 for allowing outside air to enter the inside of the reaction disk lid 1 is formed. This apparatus is used for a reaction tank 7 described later.
Is maintained at a constant temperature of 37 ° C., which is a human body temperature, and the slit hole 8 can prevent dew condensation inside the reaction disk lid 1. In this embodiment, the slit hole 8 is a square hole, but may be a circular or lattice-like hole or a slit-like hole. Although it has been described that the arrangement of each device described above can make the entire device compact and reduce the installation area of the device, the housing 40 of the present invention has a width w1 and a depth t1 of 720 mm. . In a general building, the dimensions of a doorway to a building from the outside or a doorway to a room from a corridor or the like have a size of a swing door of about 780 mm to 900 mm. Since the size of the housing 40 of the present invention is set to 720 mm, it can be carried out without disassembling the apparatus when it is carried into an inspection room or the like. In the present embodiment, the size of the housing 40 is described as 720 mm. However, the width w1 and the depth t1 do not need to be the same, and may be in the range of 780 mm to 900 mm, which is the size of the opening door.

FIG. 5 is a hot water path diagram of the automatic analyzer in FIG. As shown in FIG. 4, an electrolyte analyzer 70 is arranged at an intermediate position between the reaction disk 3, the sample disk 12, and the reagent disk 22. Electrolyte analyzer 70
Is for analyzing and measuring chlorine, potassium, sodium and the like in blood, and usually needs to be maintained at a constant temperature of 37 ° C. close to the human body temperature. In FIG. 5, a housing 40 includes
Reaction tank 7, electrolyte analyzer 70, reagent storage 9, and heater 72
, A temperature control unit 73 and a cooling unit 71. The warm water heated by the heater 72 is sent to the reaction tank 7 and the electrolyte analyzer 70, and the reaction tank 7 and the electrolyte analyzer 70
Is kept at a constant temperature. Reaction tank 7 and electrolyte analyzer 7
0 are arranged close to each other, so that the heaters 7
The piping for supplying the hot water via 2 can be shortened, and the production cost can be reduced, the repair can be simplified, and the device can be downsized.

Next, the lid 10 for the sample disk, the lid 20 for the reagent disk, the arm of the sample dispenser 14 and the reagent dispenser 24
The relationship between the rotation ranges of the arms will be described.

FIG. 6 is a cross-sectional view of the sample disk lid. FIG. 7 is a cross-sectional view of the reagent disk lid.
4, 6 and 7, the sample disk cover 10
Has a smooth upper surface, and the nozzle guard groove 46a is moved from the end a on the reaction disk side of the sample disk lid 10 to the position on the sample disk 12 along the rotation orbit of the arm of the sample dispenser 14. b, and further up to a position c in the direction perpendicular to the left, and are continuously arranged in a range from the near side of the housing 40 to the left end as viewed from the near side. In the nozzle guard groove 46a, the sample dispenser 1 is placed at a position corresponding to the position of the sample container 11.
It has an opening 47a into which the fourth nozzle 13 is inserted.

The nozzle guard groove 46a can prevent an operator's finger from being caught in a gap formed between the top plate 41, the sample disk 12, and the nozzle 13 of the sample dispenser 14. . When the setting of the sample is completed, the sample can be supplied while the sample disk lid 10 is set on the sample disk 12, so that dust and the like can be prevented from adhering to the sample.

The reagent disk lid 20 has a smooth upper surface, and has a nozzle guard groove 46 b along the rotation orbit of the arm 23 of the reagent dispenser 24. It has an opening 47b into which the nozzle 23 of the reagent dispenser 24 is inserted at a position corresponding to the position. The nozzle guard groove 47a can prevent an operator's finger from being trapped in a gap formed between the top plate 41, the reagent disk 22, and the nozzle 23 of the reagent dispenser 24. When the setting of the reagent is completed, the reagent can be supplied while the reagent disk lid 20 is set on the reagent disk 22, so that dust or the like adheres to the reagent and the reagent is kept cool (usually 8 to 12 degrees). Range)
The effect can be improved and the evaporation of the reagent can be prevented.

The sample disk cover 10 and the reagent disk cover 20 have different shapes of fitting portions between the disks 12 and 22.
Each of a and 47a is adapted to the form of the groove on the side of the reaction disk 3, so that the two can be prevented from being mistaken.

The mounting position of the sample dispenser 14 is such that the left dimension when viewed from the near side of the upper surface of the casing 40 is shorter than the length dimension of the arm 13 of the sample dispenser 14. The position a of the reaction disk 3, the position b of the sample disk 12, and the position c protruding are located on the left side of the front side of the housing 40 within the rotation orbit. Thus, when another apparatus is installed and used on the left side when viewed from the front side of the present apparatus with the sample disk cover 10 set, the nozzle 13 of the sample pipettor 14 is in the nozzle guard groove. 46a and the transfer line groove 45 are continuously passed. By adjusting the rotation range of the arm of the sample dispenser 14, the transfer of a sample or the like from another device to the sample disk 12 and the reaction disk 3 can be continuously performed.

FIG. 8 is an external view of the automatic analyzer in FIG. 1 in a state where the lid for the sample disk and the lid for the reagent disk are removed. In the figure, an opening of the top plate 41 surrounding the sample disk 12 has a shutter 7 on the side of the reaction disk 3.
4 are built in. When the sample disk cover 10 is removed, the shutter 74 moves from the top plate 41 to the sample disk 12.
Side, and put the sample disk lid 10 on the sample disk 1
2, it is arranged so as to be stored in the top plate 41. Note that the shutter 74 has an opening 75 through which the nozzle 13 of the sample dispenser 14 is inserted at a position corresponding to the position of the sample container 11.

As described above, the shutter 74 automatically performs the protruding and storing operations by attaching and detaching the sample disk lid 10, and when the operator sets the sample container 11 on the sample disk 12, the sample dispensing is performed. Nozzle 13 of vessel 14
Is prevented from touching, and a portion where the sample container 11 should not be set is closed, so that it is possible to prevent a sample from being set by mistake.

In this embodiment, the shutter 74 is linked with the projecting and storing operations by attaching and detaching the sample disk cover 10. However, the shutter 74 may be linked with the movement of the sample dispenser 14; Or a switch for newly instructing the movable operation of the shutter 74 may be provided.

FIG. 9 is a side view of the automatic analyzer in FIG. In the figure, the LCD 52 with a touch panel for input / output and display has an inclined surface d configured from the front side to the rear side, and the angle is 10 degrees. Since the display section is a liquid crystal and does not allow external light to enter the screen at right angles, the inclined surface d is easy to see the liquid crystal screen and is easy to press when operating the touch panel with a finger for operation.

In this embodiment, the inclined surface d is described as 10 degrees. However, the inclined surface d may have a predetermined angle and may be in a range of 3 degrees to 15 degrees.

FIG. 10 is an external view of the automatic analyzer shown in FIG. 1 provided with an emergency inspection device. In the present invention, although specific operation procedures will be described later, for each of the pre-registered sample liquids, in addition to the analysis based on the item to be analyzed, that is, the item selection information, based on the item selection information that is not registered in advance. In the case of analysis (hereinafter, referred to as an emergency test), the emergency test device 80 is used by connecting it to the housing 40 of the present device. The emergency inspection device 80 has the same height dimension and depth dimension as the height dimension and depth dimension of the housing 40,
Also, both side plates of the normal emergency inspection device 80 are not configured, the side plate 49 of the housing 40 of the present device is removed, and the emergency inspection device 80 is moved along the side surface on the side where the side plate of the housing 40 is removed, The removed side plate 49 is used by attaching it to the side of the emergency inspection device 80 opposite to the side of the housing 40. As a result, the emergency inspection device 80 does not need to constitute a side plate, so that the production cost can be reduced.

A typical use example of the above-described automatic analyzer according to one embodiment of the present invention will be specifically described.

FIG. 11 is a flowchart for explaining the processing of the analysis work and the operation of the operation by the present apparatus. FIG. 12 is a diagram showing a state of the display screen in each step of the flowchart, and FIG. 13 is a diagram showing a display screen at the time of emergency stop. With reference to these figures, the operation of analysis processing and operation by the present apparatus will be described. Note that FIG. 12 shows an example in which the sample to be analyzed is set to the twelfth of the sample container 11 and set registration is performed as a liver function, which is an item that is usually frequently analyzed.

(1) Turn on the primary power switch of the apparatus,
When the secondary power switch 43 is turned on, the disk mechanism 53 moves and activates the heater 72 to keep the temperatures of the reaction tank 7 and the electrolyte analyzer 70 constant. Until this task is completed,
Although not shown, the display of “Please wait for ○ minutes” is displayed on the display screen of the LCD 52 with a touch panel for input / output and display. When the preparation is completed, the basic first screen 200 is automatically displayed on the LCD 52 with a touch panel for input / output and display.
Are displayed (steps 101 to 103).

(2) At this time, as shown in FIG. 12, the display screen of the LCD 52 with a touch panel for input / output and display shows the address of the sample container 11 for setting the sample and the analysis work. A character information display unit 201 on which information indicating a procedure is displayed, a set registration button 202 for selecting item selection information in advance and specifying a registered analysis,
An item change button 203 for changing item selection information, a start button 204 for starting analysis, and a stop button 205 for stopping analysis work halfway are displayed. As described above, the character information display unit 201 for notifying the operation procedure
And the buttons for the operation are configured at the same time, so the operator does not need to shift his / her eyes to the other side, and furthermore, it is only necessary to perform the operation based on the character information. There is no need to concentrate on the handling of the sample container, and the mixing of samples can be prevented.

(3) Next, all reagents necessary for analysis are set on the reagent disk 22. Thereafter, the sample is set at the position specified by the character information display section 201 of the sample table 12. Item selection information is input for each sample liquid.
If the item selection information registered in advance is sufficient, the item selection information is designated by the set registration button 202 (steps 104 to 105). By setting the pre-registered item selection information to commonly used item selection information, it is not necessary to input each time, so that an input operation error or a shortened operation time can be achieved.

In the item selection information of the present invention, the item registration information which is performed particularly frequently in the ordinary analysis work is set in the set registration button 202 of the basic 1 screen 200. Item selection information other than the set registration button 202 is also set in 210. Further, on a basic 3 screen 230 described later, it is possible to arbitrarily select detailed analysis items such as blood and urine.

The analysis conditions for each item selection information are as follows:
It is supplied by the disk mechanism 53. The analysis conditions include the conditions for calculating the absorbance of the sample reaction solution, the amount of sample collected, the dispensing conditions for the first, second, and third reagents, the analysis wavelength, the standard solution concentration,
K factor and the like.

(4) Next, an analysis operation using item selection information other than the set registration button 202 on the basic 200 screen 200 will be described.

Although not shown in the flow chart of FIG. 11, in the analysis using the item selection information other than the set registration button 202, the change of the item selection information is designated by the item change button 203 on the screen 200 of the basic 1. When the item change button 203 is designated, a basic 210 screen 210 is displayed. A display unit 211 that displays the address of the sample container 11 on which the sample is set is displayed on the screen 210 of the basic 2. The sample container 11 displayed on the display unit 211
Is the sample container 1 designated on the screen 1 of the basic 1
It is the address of 1.

First, the amount of the reagent and the amount of the washing liquid to be performed as preparations for the analysis work are confirmed by the menu button 222. The menu button is terminated by a return button 223. After the preparation is completed, item selection information buttons 211, 212, 213, in which item selection information is set in advance,
The item selection information is selected from among 214, 215, 216, and 217, the item selection information is determined by the registration button 221, and the analysis is started by the start button 204.
When the analysis work is stopped halfway, the stop button 205 is designated.

In the event of an abnormality in the apparatus such as a stop of the reaction disk 3 or an abnormality in handling such as an improperly set sample, the alarm monitor button 220 lights up to notify the abnormality together with a buzzer sound. At the time of occurrence of the above-mentioned abnormality, when the basic 1 screen 200 is displayed, the display screen of the LCD 52 with a touch panel for input / output and display automatically displays the basic 2 screen 210, turns on the alarm monitor 220 and turns on the buzzer. Generates a sound. The operator or the person in charge of managing the apparatus, which recognizes the abnormality by turning on the alarm monitor button 220 or sounding the buzzer, sounds the alarm monitor button 220.
When the user presses 20, the display screen 3 showing the abnormal part shown in FIG.
00 is displayed. Abnormal display screen 300 showing an abnormal location
Has a title screen 30 showing the current date, time, and temperature.
1. Abnormal information list screen 302 showing the details of the abnormality, OFF button 303 for stopping the buzzer, scroll button 3 for scrolling the abnormal information list screen showing the details of the abnormality
04, a return button 305 for returning the abnormality display screen 300 to the basic screen after the abnormality check is completed is displayed.

As described above, the abnormality display screen 300 includes:
The location of the abnormality and the time of occurrence of the abnormality are displayed at the same time as the request number (corresponding to the sample ID number) and the current time, so that the time elapsed since the device was stopped can be known. Can be appropriately performed. Also, regardless of the state of the display screen of the LCD 52 with a touch panel for input / output and display at the time of abnormality,
Since the basic 2 screen is always displayed automatically, it is possible to quickly cope with the abnormality.

(5) Next, an analysis operation using item selection information other than the item selection information set in advance on the screen 210 of the basic 2 will be described. When the item key 218 of the basic 2 screen 210 is designated, the basic 3 screen 230 is displayed. A display unit 211 for displaying the address of the sample container 11 on which a sample is set is displayed on the screen 230 of the basic 3. It should be noted that the menu button 222, the return button 223, and the
A stop button 205 and an alarm monitor button 220 are provided, and their functions and operations are the same as those described in the basic 2 screen.

First, item selection information is selected from 40 analysis item buttons 232 such as urine and blood, and a registration button 2 is selected.
21 to confirm the item selection information,
04 starts the analysis. Note that the analysis item buttons of the present apparatus only display 12 analysis item buttons on one screen, and the next analysis item button is called by the scroll button 233.

(6) When the above preparations are completed, the operator presses the apparatus start button 204 to start the apparatus. When the apparatus is started, the analysis end time is displayed for 5 seconds on the display screen of the LCD 52 with input / output and display touch panel, and then the basic first screen 200 is automatically displayed (steps 106 to 107).
When the sample setting is completed, the basic first screen 200 for automatically setting the next sample is displayed after 5 seconds, so that the operator can set many samples quickly, Also, when another operator performs an analysis operation, it is possible to quickly set.

(7) When the analysis work is completed, the operator is notified of the completion of the work by using a telephone line.
Thereafter, the analysis result is output by the output printer 51. In addition, when an abnormality occurs, the basic 2 screen 210 is automatically displayed, the alarm monitor unit 220 is turned on, and the administrator of the apparatus is notified of the alarm display using the telephone line (steps 108 to 111). . Thus, even if the operator is away from the apparatus or forgets the end time described above, the operator can know that the analysis work has been completed or an abnormality, so that the operator can concentrate on things other than the analysis work. It can reduce the mental burden.

The display screen of the LCD 52 with the touch panel for input / output and display includes a sample on which a sample is always set on all of the basic 1 screen 200, the basic 2 screen 210, and the basic 3 screen 230. Since the address of the disk 12 is displayed, the operator can easily recognize where the sample is to be set, and it is possible to prevent a mistake in sample mixing.

Next, the emergency specimen will be described. FIG.
FIG. 5 is a diagram showing an operation procedure of an emergency inspection. FIG.
FIG. 15 is a diagram showing a procedure for outputting an analysis result in FIG. 14. In FIG. 14, the emergency test uses a test card 401 that serves as both a test request and a report, instructs the apparatus to specify item selection information, and outputs the analysis result to the test card 401. The request number 402 (corresponding to the sample ID number) is described on the test card 401,
Further, a bar code label 403 indicating the request number 402
Is attached. Next, an operation procedure of the emergency inspection will be described with reference to FIGS.

(A) The barcode label 403 affixed to the test card 401 is peeled off, affixed to the sample container 11, and the sample container 11 is set on the sample disk 12.

(B) The analysis items described in the mark sheet section 404 of the inspection card 401 are marked and the item selection information is designated.

(C) One inspection card 401 is inserted into the card insertion slot 81 arranged on the upper surface of the emergency inspection device 80.

(D) The emergency inspection device 80 is
1 is read, and the sample ID information is identified.

(E) The emergency inspection device 80 is
The item selection information marked on the first mark sheet section 404 is read, and the item selection information is identified.

(F) The emergency test apparatus 80 transmits the sample ID information and the item selection information to the automatic analyzer of the present invention.

(G) From the emergency inspection device 80 to the inspection card 4
01 is discharged from the card discharge port 82 arranged on the upper surface of the emergency inspection device 80.

(H) The steps (a) to (g) are repeated for the test card 401 for the next sample. (I) Insert the inspection card 401 read in the step (c) into the card insertion slot 81.

(J) The emergency test apparatus 80 reads the request number 402 of the test card 401 again and identifies the sample ID information.

(K) If all the analysis results requested by the inspection card 401 read in the step (i) are already available, the analysis results are sent to the emergency inspection device 80 by the automatic analysis of the present invention. Sent from the device.

(L) The analysis result is printed in the analysis result output column 405 of the inspection card 401 by the emergency inspection device 80.

(M) When all the analysis results have not yet been collected, the inspection card 401 is discharged from the emergency inspection device 80.

(N) The steps (i) to (m) are repeated for the test card 401 for the next sample.

In the above-described emergency inspection, the inspection card 4
01 shows all of the sample ID information, item selection information, and analysis results, so that even an operator who is not accustomed to handling can obtain the request number 40 affixed to the sample container 11.
2 and the request number 402 of the test card 401 are collated by the automatic analyzer of the present invention to perform an analysis operation, so that an operation error or a mistake between a sample and a test result can be prevented.

[0070]

According to the present invention, the lids 1, 10, and 20, ie, the lids of the containers, and the lid 30 for the dispensing mechanism are formed independently of each other. Compared to the conventional large lid that covers the entire device, including the unused parts, all parts that do not need to be exposed are always covered with the lid, so the operator can touch the sample or use the dispensing mechanism. Because it is not touched, safety during use can be improved. When the reagent setting is completed,
Since the reagent supply operation can be performed while the lid of the reagent container is installed in the reagent container, it is possible to prevent dust and the like from adhering to the reagent, to improve the effect of keeping the reagent cool, and to prevent evaporation of the reagent.

[Brief description of the drawings]

FIG. 1 is an external view of an automatic analyzer according to an embodiment of the present invention.

FIG. 2 is a principle diagram of a main part of the automatic analyzer in FIG.

FIG. 3 is an exploded view of the automatic analyzer in FIG.

FIG. 4 is a plan view of the automatic analyzer in FIG.

FIG. 5 is a hot water path diagram of the automatic analyzer in FIG. 1;

FIG. 6 is a cross-sectional view of a lid for a sample disk.

FIG. 7 is a cross-sectional view of a reagent disk lid.

8 is an external view of the automatic analyzer in FIG. 1 in a state where a lid for a sample disk and a lid for a reagent disk are removed.

FIG. 9 is a side view of the automatic analyzer in FIG.

FIG. 10 is an external view of the automatic analyzer shown in FIG.

FIG. 11 is a flowchart illustrating an analysis operation process and an operation performed by the apparatus.

FIG. 12 is a diagram showing a state of a display screen in each step of the flowchart.

FIG. 13 is a diagram showing a display screen at the time of an emergency stop.

FIG. 14 is a diagram showing an operation procedure of an emergency inspection.

FIG. 15 is a diagram showing a procedure for outputting an analysis result in FIG. 14;

[Explanation of symbols]

 REFERENCE SIGNS LIST 1 reaction disk lid 3 reaction disk 10 sample disk lid 12 sample disk 14 sample dispenser 20 reagent disk lid 22 reagent disk 24 reagent dispenser 30 dispensing mechanism lid 40 housing 52 input / output and display touch panel With LCD 200 Basic 1 screen 210 Basic 2 screen 230 Basic 3 screen.

 ──────────────────────────────────────────────────続 き Continuing on the front page (72) Inventor Isamu Takekoshi 1-280 Higashi Koigabo, Kokubunji-shi, Tokyo Inside the Design Laboratory, Hitachi, Ltd. Measuring Instruments Division (72) Inventor Kahei Shiraishi 1040 Ma, Hitachinaka-shi, Ibaraki Pref.Hitachi Science Systems, Ltd. (Reference) 2G058 AA05 AA09 CB04 CD04 CF12 EA02 EA04 EA07 EB01 ED04 GA01 GA11 GC01 HA01

Claims (9)

[Claims] 1. A sample dispenser for dispensing a sample container, a reagent container, a reaction container, a sample from the sample container to the reaction container, and a reagent dispenser for dispensing a reagent from the reagent container to the reaction container,
An automatic analyzer that analyzes the components of a sample by reacting the sample and the reagent in the reaction container, wherein a top plate that is separable from the housing is provided on an upper surface of the housing, and the top plate includes a sample. The container, the reagent container, and the reaction container are each provided with an opening at a portion corresponding to each part so as to be exposed, and the opening has a lid that covers the sample container and a lid that covers the reagent container. And a lid that covers the reaction vessel are provided independently of each other, and the top plate is provided with a lid for a dispensing mechanism that covers the sample dispenser and the reagent dispenser. Automatic analyzer. 2. A dispensing mechanism according to claim 1, wherein the sample dispenser and the reagent dispenser each have an arm, and an opening of the top plate from which the sample dispenser and the reagent dispenser are exposed is provided. A base is provided, and the top plate can be removed from the housing without removing the arm of the sample dispenser and the arm of the reagent dispenser by removing the lid and the dispensing mechanism base. apparatus. 3. The automatic analyzer according to claim 2, wherein the dispensing mechanism base is composed of two or three members. 4. A sample dispenser for dispensing a sample container, a reagent container, a reaction container, a sample from the sample container to the reaction container, and a reagent dispenser for dispensing a reagent from the reagent container to the reaction container,
An automatic analyzer that analyzes the components of a sample by reacting the sample and the reagent in the reaction container, wherein a top plate that is separable from the housing is provided on an upper surface of the housing, and the top plate includes a sample. An opening is formed in a portion corresponding to the site so that the container is exposed, a lid is provided on the opening to cover the sample container, the sample dispenser has an arm, and a lid for the sample container is provided. A groove is provided along the trajectory of the arm of the sample dispenser, and the groove is provided with an opening at a position synchronized with the position where the sample container holding the sample is arranged. Automatic analyzer. 5. A sample dispenser for dispensing a sample container, a reagent container, a reaction container, a sample from the sample container to the reaction container, and a reagent dispenser for dispensing a reagent from the reagent container to the reaction container,
An automatic analyzer that analyzes the components of a sample by reacting the sample and the reagent in the reaction container, wherein a top plate that can be separated from the housing is provided on an upper surface of the case, and the top plate includes a reagent An opening is formed in a portion corresponding to that part so that the container is exposed, a lid covering the reagent container is provided in the opening, the reagent dispenser has an arm, and a lid for the reagent container is provided. A groove is provided along the trajectory of the arm of the sample dispenser, and an opening is provided in the groove in a position synchronized with a position where the reagent container holding the reagent is arranged. Automatic analyzer. 6. The automatic analyzer according to claim 4, wherein the cover for covering the sample container or the cover for covering the reagent container has a smooth surface. 7. The sample dispenser according to claim 1, wherein the groove provided along the trajectory of the arm of the sample dispenser is provided on a top plate along the arm trajectory of the sample dispenser. An automatic analyzer characterized by being continuous with a line groove. 8. The sample container according to claim 1, wherein when the sample container lid is removed to expose the sample container, a gap between a tip of a nozzle held by an arm of the sample dispenser and an upper surface of the sample container is formed. When the cover was concealed and the lid for the sample container was attached to the upper surface of the sample container, a member for opening the gap between the tip of the nozzle held by the arm of the sample dispenser and the upper surface of the sample container was provided. An automatic analyzer, characterized in that: 9. A sample dispenser for dispensing a sample container, a reagent container, a reaction container, a sample from the sample container to the reaction container, and a reagent dispenser for dispensing a reagent from the reagent container to the reaction container,
In the automatic analysis method for analyzing the components of a sample by reacting the sample and the reagent in the reaction container, a lid covering the sample container, a lid covering the reagent container, and a lid covering the reaction container are independently provided. Automatic opening characterized by rotating the respective arms of the sample dispenser and the reagent dispenser so that the nozzle attached to the arm is located at the exposed portion. Analysis method.