JP2002065648A - Blood collecting method - Google Patents

Abstract

PROBLEM TO BE SOLVED: To collect a required amount of blood well enough in a short time from any part of the body even if a stick is shallow and narrow. SOLUTION: This invention relates to a blood collecting method by sticking the skin of a living body and exuding body fluids therefrom. Firstly, a part on which a blood collecting tool is tightly touched with the skin is made in a sealed condition, and then the pressure in the vicinity of the stuck point is decreased by repeating decompression and release.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a blood sampling method used in an apparatus (instrument) for analyzing a blood component with a small amount of blood, such as a simple blood glucose meter, and more particularly to a blood sampling method from any part of the body with a shallow and narrow puncture. The present invention relates to a technique for sufficiently collecting a required amount of blood in a short time.

[0002]

2. Description of the Related Art Heretofore, there have been the following problems with the blood collection method by puncture proposed in the United States and other countries.

That is, in the conventional blood collection method, the blood pressure at the puncture point is increased by pressurization near the puncture point. However, the blood flow is blocked by the pressurization, and the amount of blood existing near the puncture point is increased. Tended to be limited. In that state, no matter how much pressure is applied, a sufficient amount of blood cannot be obtained.

[0004] US Patent No. 5,964,741 (Title of Invention "BODY
FLUID SAMPLING DEVICE '', filed Mercury Diagnost
ics. Inc.), there is a method of collecting blood in the direction of the puncture point by applying pressure with a ring cut diagonally around the puncture point, but even if this method has the effect of increasing blood pressure somewhat, The quantity cannot be secured sufficiently. In order to ensure a sufficient blood collection volume by pressurization, it is necessary to sufficiently increase the blood pressure and blood volume near the puncture point in advance.

Further, US Pat. No. 5,951,493 (title of "METHODS AND APPARATUS FOR EXPRESSING BODY FLUI")
D FROM AN INCISION, application Mercury Diagnostics. In
In c.), the effect of pinching the skin with the blade at the tip of the device is described, but a sufficient amount of blood collection cannot be ensured by pinching the skin. In order to ensure a sufficient level, it is sufficient if the skin can be sufficiently raised and squeezed from the root of the skin to the vicinity of the puncture point in the manner of so-called "milking a cow".

[0006] Regarding the blood sampling method by suction, see
No. 255706 (Title of Invention `` Simple Blood Sampling Device '', Application: Advance Co., Ltd.) describes a device that combines suction and puncture, but with regard to suction, simple suction only requires a device for suction. Blood vessels are blocked by strong contact with the skin, blood flows out from the puncture point, and blood pressure near the puncture point decreases. If the suction power is increased to counteract this, there is a problem that purpura such as congestion of the skin remains, and pain is caused by pulling the skin and friction between the device and the device during suction. With regard to purpura, if it remains on the arm, it will be embarrassing for women to be exposed in summer, and it will also develop into a problem that it looks bad.

[0007]

SUMMARY OF THE INVENTION The present invention has been made in view of the above circumstances, and provides a blood collection method capable of sufficiently collecting a required amount of blood from any part of the body in a short time while being a shallow and narrow puncture. The purpose is to provide.

[0008]

A blood collection method according to a first aspect of the present invention is a blood collection method for puncturing skin of a living body with a puncturing means and exuding a body fluid in the living body to the outside to collect the blood. It is characterized in that the part brought into contact with the skin is kept in a sealed state, and the pressure in the vicinity of the puncture point is reduced while repeating "decompression and release". According to such a configuration, the effect of blood outflow can be enhanced by several steps, and a required amount of blood can be sufficiently collected from any part of the body in a short time, even with a shallow and narrow puncture.

[0009] The blood collection method according to claim 1 of the present invention is characterized in that the degree of pressure reduction is set between 15 kPa and 80 kPa. According to such a configuration, by setting the degree of decompression and the repetition interval in the above ranges, the symptoms can be prevented even at 40 kPa, which usually becomes congested when continuously sucked.

[0010] The blood collecting method according to claim 1 or 2 of the present invention is characterized in that the tip of the skin contact portion of the instrument or its vicinity protrudes in the direction of the puncture point. According to such a configuration, the presence of the protruding portion allows the skin raised by suction to be pressurized by the protruding portion while securing a large amount of blood vessels and blood to be blocked around the puncture point by decompression. The effect of the spill can be increased.

[0011] A blood collection method according to a fourth aspect of the present invention is a blood collection method in which the skin of a living body is punctured by a puncturing means, and a body fluid in the living body is exuded out of the body and collected. Pressurize, raise the skin near the puncture point with the puncture point,
It is characterized by sandwiching the raised skin.
According to such a configuration, the blood can easily come out.

A blood collection method according to a fourth aspect of the present invention is characterized in that the raised skin and the skin contact portion of the device are brought closer to each other in the puncturing direction. According to such a configuration, blood is more likely to come out.

The blood collection method according to claim 5 of the present invention is characterized in that, when the raised skin is sandwiched, the pressure applied to the skin is applied in the order from the puncture point to the puncture point. Is what you do. According to such a configuration, the effect of further squeezing out blood near the puncture point is enhanced.

In this case, as in the blood collecting method according to the sixth aspect of the present invention, the air which is attached to the tip of the skin contact portion of the device and expands and contracts to a certain size by air pressure. It is also preferred that the raised skin be sandwiched between bags.

A blood collection method according to a fourth aspect of the present invention is characterized in that a skin contact portion of an instrument is moved so that a force in a shear direction is applied to a puncture point on the skin. Things. According to such a configuration, both the pressurizing effect and the squeezing effect can be applied to the skin near the puncture point, and the blood outflow effect is further improved.

A blood collection method according to a ninth aspect of the present invention is a blood collection method in which the skin of a living body is punctured by a puncturing means, and a body fluid in the living body is exuded out of the body and collected. It is characterized in that the surrounding area is pressed, the skin near the puncture point is raised together with the puncture point, and the device contacts the skin and pressurizes the raised skin. According to such a configuration, it is possible to efficiently perform blood outflow from the puncture point.

According to a ninth aspect of the present invention, there is provided a blood collection method according to the ninth aspect, wherein a pressure is applied around a puncture point by a cuff which is made of a flexible material such as a manchette and is inflated and contracted by air pressure. In addition, the skin near the puncture point is raised. According to such a configuration, by increasing the air pressure, the cuff expands to a certain volume, the blood pressure of the skin raised from the puncture point formed in a part of the cuff increases, and the blood outflow effect can be enhanced. .

A blood collection method according to a tenth aspect of the present invention is characterized in that the cuff expands from around the puncture point toward the puncture point and presses around the puncture point. According to such a configuration, instead of simply inflating the entire cuff at once, blood is inflated around the puncture point from the outside toward the puncture point to increase blood pressure from the periphery to the puncture point. Has the effect of collecting
In addition, it enhances the blood outflow effect.

A blood collection method according to a ninth aspect of the present invention is characterized in that, when the raised skin is pressurized, pressure is applied from outside the puncture point toward the puncture point. According to such a configuration, the blood is collected toward the puncture point, the blood pressure near the puncture point is further increased, and a sufficient blood collection amount can be secured.

According to a ninth aspect of the present invention, there is provided a blood collection method according to the ninth aspect, wherein an air bag attached to the tip of the skin contact portion of the instrument and inflated and contracted to a certain size by air pressure near the puncture point. , And pressurizing the raised skin. According to such a configuration, it is possible to increase the blood pressure while applying pressure from the surroundings toward the puncture point.

[0021] Claims 9 to 1 shown in claim 14 of the present invention.
In the blood collection method according to any one of the above, the skin contact portion of the instrument has at least two or more multi-cylindrical structures, and when pressed against the skin around the puncture point, the skin is sequentially moved from the outer cylinder toward the inner cylinder. Pressure is applied, and the skin near the puncture point is raised together with the puncture point to apply pressure. According to such a configuration, the inner cylinder functions to collect the blood stopped by the outer cylinder further toward the center (the direction of the puncture point).

The ninth to the first aspects of the present invention are as follows.
The blood collection method according to any one of (2) is characterized in that the cylinder is rotated at the time of pressurizing the tip of the cylindrical structure of the skin contact portion of the device. According to such a configuration, the skin is in a so-called squeezed state in conjunction with the rotation of the cylinder, and has an effect of squeezing the blood that has been blocked by the cylinder to the outside of the body.

[0023] Claims 4 to 1 in claim 16 of the present invention.
The blood collection method according to any one of the fifth to fifth aspects is characterized in that, in addition to the pinching around the puncture point on the skin and the blood collecting action of pressurization, the pressure in the vicinity of the puncture point including the puncture point is reduced. According to such a configuration, the effect of blood outflow is further enhanced.

Claims 4 to 1 according to claim 17 of the present invention.
5. The blood collection method according to any one of claims 5 to 5, wherein
Is repeatedly performed by one operation. According to such a configuration, by performing the operation with one operation of the user, it is possible to very easily obtain a high effect of blood outflow.

[0025]

DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS Hereinafter, an apparatus (apparatus) for carrying out the blood sampling method of the present invention will be described with reference to the drawings.

In a blood collection method in which blood is collected by puncturing the skin 1, there is a large difference in the amount of blood collected depending on the difference in blood vessel density and blood pressure in the body, the mental state of the person, and the tension of the skin 1 due to the ambient temperature. Occurs. Therefore, in order to ensure a sufficient amount of blood collected by puncturing in any state, it is necessary to take measures in addition to puncturing to promote blood outflow to the vicinity of puncturing point 3 (a blood cell is shown in the drawing). . In order for blood to flow out of the body, if the left side is larger than the right side in the following inequality, the blood basically flows out of the body. (1) Blood pressure> (2) Atmospheric pressure (ambient pressure) + (3) Wound closing action + (4) Vascular pressure loss (the above relational expression is hereinafter referred to as “inequality for blood outflow”). ) Blood pressure (pressure of blood in skin blood vessels) is (2) to (4) on the right-hand side.
(3) the force that tries to block blood vessel and cell wounds created by the needle, and (4) the pressure loss that the blood in the blood vessel loses before reaching the damaged blood vessel). If so, blood will flow out of the body. Therefore, assuming that the force for closing the blood vessel or cell wound created by the needle of (3) on the right side is constant, in order to secure a sufficient blood collection volume, (1) means for increasing the blood pressure on the left side Is applied. Alternatively, means (2) on the right side for reducing the atmospheric pressure (ambient pressure) is applied. Or it can be seen that it is better to perform them simultaneously.
Hereinafter, the blood collection method of the present invention will be described in detail in the order of claims.

The blood collection method according to claim 1 is a blood collection method in which the skin 1 of a living body is punctured by a puncturing means, and a body fluid in the living body is exuded out of the body and collected. In a sealed state, the pressure near the puncture point is reduced while repeating "decompression and release".

By reducing the pressure around the puncture point without applying pressure or the like, the surrounding pressure on the right side (2) of the inequality for blood outflow is reduced, and as shown in FIG. The effect increases. However, at the time of decompression, as the pressure decreases, the force of the suction member to adhere to the skin increases, so that blood is blocked there. Therefore, if the decompression is continued as it is, the amount of blood that can be collected is limited to only the blood located inside the cutoff (in the direction of puncturing point 3). Further, as the blood flows out from the puncture point 3, the blood pressure loss around the puncture point 3 in the same manner as in the above (4) increases, so that the blood outflow gradually decreases. Therefore, by intermittently repeating the depressurization, the external pressure, and the depressurization as described above, as shown in FIGS. 17B to 17C, the blood pressure decreases after the blood flows out of the puncture point 3 during the depressurization. The blood stopped at the time of releasing the decompression to the puncture point 3 (the blood stopped outside the suction member) flows into the puncture point 3 at a stretch, and the blood pressure around the puncture point 3 increases, and the pressure is reduced at that moment. Thus, the effect of blood outflow from the puncture point 3 is increased by several steps. This repetition interval is 0.3 ~
It is preferable to repeat at intervals of about 3.0 seconds.

In the blood collecting method according to the second aspect, the degree of reduced pressure is set between 15 kPa and 80 kPa.

By setting the degree of decompression and the repetition interval in the above ranges, congestion will occur if suction is normally performed continuously.
kPa can also prevent symptoms.

In the blood collecting method according to the third aspect, the tip of the skin contacting portion of the instrument A or the vicinity thereof has a shape protruding in the direction of the puncture point 3.

As shown in FIG. 18, since the protrusion 23 is provided near the skin of the holding member 24 of the device A, the volume of the blood vessel and blood that is blocked around the puncture point 3 by the pressure reduction is increased, and the volume rises by suction. Skin 1
As shown in FIG. 9, the protruding portion 23 automatically becomes pressurized,
The effect of blood efflux increases.

The blood collection method according to the fourth aspect is a blood collection method in which the skin 1 of a living body is punctured by a puncturing means to exude body fluid in the living body to the outside of the body to collect the blood. By pressurizing, the puncture point 3 and the skin 1 near the puncture point 3 are raised, and the raised skin 1 is sandwiched.

In order to sandwich the skin 1 around the puncture point 3, first, as shown in FIG. 8 to FIG. As a result, the skin 1 is sufficiently pinched when sandwiched, so that the puncture point 3
8 (a) to 8 (c), the skin 1 in the vicinity of the puncture point 3 is raised by raising the blood pressure on the left side (1) of the "inequality for blood outflow". Has the effect of squeezing out. Reference numeral 2 indicates the direction of blood flow. At the same time, the wound caused by the puncture is spread as shown in FIG. 9, so that it is difficult to occlude, and the left side (3) of the “inequality for blood outflow” becomes smaller, so that the blood is more likely to come out. Reference numeral 9 indicates a direction in which the skin 1 is pulled, and reference numeral 10 indicates a direction in which the skin 1 is pressed.

In the blood collecting method according to the fifth aspect, the raised skin 1 and the skin contact portion of the device A are made to approach each other in the puncturing direction (see FIG. 10).

At the time of sandwiching, the sandwiching tools 8, 8 of the blood collection device (instrument A) pressed against the puncture point 3 may be brought close as shown in FIG. 8B, or one of the sandwiching tools 8 is fixed. Alternatively, the other holding member 8 may be brought closer as shown in FIG.

In the blood collection method according to the sixth aspect, when the raised skin 1 is sandwiched between the sandwiching tools 8, 8, the pressure applied to the skin 1 is sequentially increased from the far side of the puncture point 3 toward the puncture point 3. It is intended to be hung.

As shown in FIGS. 8 (a) to 8 (c), a straight surface is basically pressed against the puncture point 3 from the side far from the puncture point 3 by simply horizontally sandwiching it with the jaws 8 and 8. Pressurization is applied in order, but the effect of further squeezing out the blood near the puncture point 3 is further enhanced by attaching the projection 23a to the skin contact portion of the blood collection device (instrument A) as shown in FIGS. .

According to a seventh aspect of the present invention, the raised skin is sandwiched by an air bag which is attached to the tip of the skin contact portion of the device and inflates and contracts to a certain size by air pressure.

The inflation of the bag at the tip due to air pressure is shown in FIG.
It is preferable to adopt a structure as shown in (a) to (d), in which the inflation stops when the bags reach a certain size so that the bags do not come into contact with each other. Reference numeral 14 denotes an air flow, and reference numeral 17 denotes a pressing tool which is hollow and has a balloon-like body 18 at its tip. A blood collection method according to a fourth aspect of the present invention is characterized in that the skin contact portion of the instrument A is moved so that a force in a shear direction is applied to a puncture point on the skin.

As shown in FIG. 11, when the clipping tool 8 is pressed, the clipping tool 8 is moved not in the direction of the puncture point 3 but in the direction in which the puncture point 3 is sheared. Both the pressurizing effect and the squeezing effect can be added, and the blood outflow effect is further improved.

According to the blood collection method of the ninth aspect, the area around the punctured puncture point 3 on the skin 1 is pressed to raise the skin 1 near the puncture point 3 together with the puncture point 3, and the device A comes into contact with the skin 1. Pressurizes the raised skin 1.

The area around the puncture point 3 is pressurized to raise the vicinity of the puncture point 3, so that (1) the blood pressure of the protruding portion including the puncture point 3 is stopped in an increased state. By pressurizing the raised portion in this state, the height is further increased, and blood can flow out from the puncture point 3 efficiently.

In the blood collecting method according to the tenth aspect, the puncture point 3 is formed by a cuff 13 made of a flexible material such as a manchette (a rubber bag covered with a sphygmomanometer cloth) and expanded and contracted by air pressure. To swell the skin 1 near the puncture point 3 together with the puncture point 3.

The bag (cuff 13) is increased by increasing the air pressure like a manchette (rubber bag covered with cloth) of a blood pressure monitor.
Expands to a certain volume. Then, as shown in FIG.
The blood pressure of the raised skin 1 increases from the puncture point made in a part of the skin 3. This action enhances the blood outflow effect. Reference numeral 11 denotes an arm, 12 denotes a puncture cuff hole, and 15 denotes an air supply port.

In the blood collecting method according to the eleventh aspect, the cuff 1
3 expands toward the puncture point 3 from around the puncture point and presses around the puncture point 3.

In the present invention, the cuff 13
The blood does not expand all at once, but expands around the puncture point 3 so that the air pressure increases from the outside toward the puncture point 3, thereby collecting blood from the periphery toward the puncture point 3. Yes, (1) blood pressure around the puncture point 3 is further increased, and the blood outflow effect is enhanced.

The above effect can be obtained by using the cuff 13 that can tighten the entire arm 11 as shown in FIGS. 14A to 14C, for example, as shown in FIGS. It has the effect of collecting blood toward it. Reference numeral 16 denotes a forearm cuff.

In the blood collection method of the twelfth aspect, when the raised skin 1 is pressurized, the pressure is applied from outside the puncture point 3 toward the puncture point 3.

By further pressing the raised portion toward the skin 1 in order from the outside centering on the puncture point 3, blood is collected toward the puncture point 3. Therefore, the blood pressure in the vicinity of the puncture point 3 is further increased, and a sufficient blood collection amount can be secured. The cuff 13 which expands from the periphery of the puncture point 3 toward the puncture point 3 and presses the periphery of the puncture point 3 according to the invention of claim 10 further expands to a position where the cuff 13 further presses the raised skin 1 and the vicinity of the puncture point 3. You may.

In the blood collection method of the thirteenth aspect, the device A
The skin 1 in the vicinity of the puncture point 3 is raised by an air bag attached to the tip of the skin contacting portion and inflated and contracted by air pressure to a certain size, and the raised skin 1 is pressurized.

As shown in FIG. 15D, the holding member 17 in the form of a hollow bag can increase the blood pressure while pressurizing the surroundings toward the puncture point 3 by expanding the balloon-like body 18 downward. I can do it.

In the blood collection method of the fourteenth aspect, the device A
The skin contact portion has at least two or more multiple inner cylinder structures, and when pressed against the skin 1 with the puncture point 3 as the center, the skin 1 is pressed from the outer cylinder 4 toward the inner cylinder 5 sequentially,
Further, the puncture point 3 and the skin 1 near the puncture point 3 are raised and pressurized.

As shown in FIGS. 1 (a) to 1 (c), it has a multi-cylinder structure of two or more, and when pressed against the skin 1, the skin 1 is pressurized from the outermost cylinder 4 located at the outermost side. As a result, the blood stopped by the outer cylinder 4 is further collected by the inner cylinder 5 toward the center (in the direction of the puncture point 3). The outermost outer cylinder 4 also serves to fix the position. With respect to the cylinders 4 and 5, when the pressure on the skin 1 is released, the inner cylinder springs 31 and the outer cylinder springs 32 are used so that the cylinders 4 and 5 return to the initial state shown in FIG. It is very convenient to repeat the operation by controlling. Regarding the diameter of the cylinder, the outer diameter of the outermost outer cylinder 4 is preferably φ35 mm or less so that it does not protrude when pressed against the arm 11, and the inner diameter of the innermost inner cylinder 5 is in contact with the blood that has flowed out. Φ3mm to avoid
The above is preferred. Reference numeral 25 denotes a needle, reference numeral 26 denotes a needle main body, reference numeral 27 denotes a needle fixing base, reference numeral 28 denotes a fixed base movable rail, reference numeral 29 denotes a blood sampling apparatus main body, and reference numeral 30 denotes a suction pump.

In the blood collecting method according to the fifteenth aspect, the device A
At the time of pressurizing the tip of the cylindrical structure of the skin contact portion of
5 is rotated.

As shown in FIGS. 2 (a) and 2 (b), the entire inner / outer cylinders 4, 5 or the inner cylinder 5 of the device A pressed against the skin have a large contact resistance with the skin 1 and rotate, so that the skin 1 Is brought into a so-called squeezed state in conjunction with the rotation of the cylinders 4 and 5, and has an effect of squeezing out the blood caught by the cylinders 4 and 5 out of the body. At this time, in order to increase the frictional resistance, the shape of the tip end of the cylinder 5 may be formed into an uneven structure 6 as shown in FIG. It can also be achieved by setting the material of the tip of the cylinder 5 to a material having high adhesion and adhesion to the skin 1, such as general rubber, vinyl chloride, nylon, and polyolefin. Of course, both the shape and the material may have high frictional resistance. The usability is further improved by adopting a structure in which the rotation of the cylinder is changed in the degree of twist according to the degree of pressing as shown in FIG. As shown in FIG. 4, the projections 7 of the inner cylinder 5 are inserted into the grooves 56 of the outer cylinder 4, so that the cylinders 4, 5 are relatively rotated.

Further, as shown in FIGS. 6 and 7, the tip of the inner cylinder 5 has an inclination angle .theta. Of 5 to 30.degree. The tip is also pressurized to collect blood from outside to inside.
If the angle θ of the tip is too large, a sufficient contact area with the skin 1 cannot be secured, and if it is too small, the effect of collecting blood inward will be weakened. Also, as shown in FIGS. 6A and 6B, the angle θ at the tip is the angle with respect to the horizontal of the straight line connecting the tip of the outer wall and the tip of the inner wall, and two points may be connected by a straight line. (B) By curving so as to protrude outward as in (c), the effect of further collecting blood toward the puncture point 3 is enhanced. However, when it is curved outward, the effect of sending blood inward is reduced if the tip is extremely below horizontal as shown in FIG. 7 (c). There is no problem if the contact portion of the outer diameter tip portion with the skin 1 in FIG. 7A is chamfered to R2 or less.

[0058] In the blood collecting method according to claim 16, the skin 1
In addition to the pinching around the puncture point 3 above the puncture point 3 and the blood collecting action of pressurization, the pressure near the puncture point 3 including the puncture point 3 is also reduced.

By reducing the pressure including the puncture point 3 while applying pressure, the left side (1) of the above inequality of blood outflow is increased while the blood pressure is increased while the right side (2) is reduced. The effect of the outflow is higher (see FIG. 21). Symbol X indicates the outer diameter of the outer cylinder 4 before operation, and Y indicates the inner diameter of the inner cylinder 5.

[0060] In the blood collecting method of the seventeenth aspect, the above operation is repeatedly performed by one operation.

With respect to the above squeezing and pressurization, the left side of the inequality of blood outflow (1) increases the effect of blood outflow by increasing blood pressure, but the right side (4) increases with blood outflow.
Since the vascular pressure loss gradually increases, the effect of increasing the blood pressure on the left side (1) gradually decreases. Therefore, the effect of increasing the blood pressure is restored by releasing the pressurization immediately after the blood once comes out, returning to the initial state, and repeating the same operation. Furthermore, because blood pressure when blood flows in where blood around the puncture point has decreased is higher than the initial state,
The effect of blood efflux is more than the initial.

The repetitive operation is performed in the shape of the device A shown in FIG. 16A, that is, the meandering guide groove 50 in which the projections 19, 19 protruding from the clipping member 8 are formed in the outer cylinder wall 20.
And the pinching tools 8, 8 as the outer cylinder wall 20 moves up and down.
Mechanical means to move the camera closer or farther away by shaking it left or right, or
As shown in FIG. 16 (b), a linear drive unit 2 in which a permanent magnet 21 provided at the tip of
There is a means for driving by means of 2, and by performing the operation with one operation of the user, it is possible to very easily obtain a high effect of blood outflow.

In addition, in all of the embodiments of the present invention, the puncture needle 3 and the member for pressurizing or suctioning are integrated, and there is no time difference between the action for promoting blood outflow of pressurizing and suctioning. By activating, the above-mentioned (3) wound closing effect such as blood coagulation due to the passage of time is prevented from increasing, and the efficiency of blood outflow from the puncture point 3 is increased.

In addition, it is possible to improve the usability such that the operation can be performed with one hand by integration (see FIG. 20).

The timing at which the puncture needle 3 is actuated does not interfere with the blood outflow effect immediately before, simultaneously or immediately after the action of promoting the blood outflow by pressurization and suction.

Further, the member for effecting the blood outflow is connected to the skin 1
When pressed against the needle, the pressure causes the blood to flow out and the needle 25
If the operation switch 51 is turned on, the usability is also improved (see FIGS. 24B and 24C). Reference numeral 52 denotes a suction switch.

In order to prevent the switches 51 and 52 from being turned on unless the switch is pressed against the skin 1 as described above, the switch member presses the skin pressing portion to the vicinity of the puncture point 3. If so, painless puncture by compression masking can be performed simultaneously (FIG. 25B).
(D)).

Further, as shown in FIG.
Is connected to the on / off switch 53 of the suction pump 30 and the needle fixing base operation switch 54,
When pressed with 4, the leak hole 33 is closed and suction and puncture are performed simultaneously. Then, when the finger 34 is released, the leak and the turning off of the suction pump 30 can be performed at the same time, so that the suction safety and operation can be performed at the same time, which is very convenient.

Also, as shown in FIG. 23, if the dome 36 is provided at the tip of the blood collecting device (instrument A) with a transparent material whose contents can be confirmed, when blood is collected from a portion away from the eyes such as the thigh, It is easy to check the blood collection from any angle. Reference numeral 39 is an eye. Also, as shown in FIG. 23, it is easy to confirm the appropriate amount by attaching the lens 37 and the like to greatly enlarge the state of bleeding. Further, by providing the appropriate amount line 38, when the blood ball 55 due to bleeding becomes the size of the appropriate amount line 38 when viewed from the outside, an appropriate amount of blood can be collected, and unnecessary blood collection can be avoided. Usability is further improved.

In addition, by integrating the blood glucose meter and the blood sampler, puncturing, blood sampling, and measurement can be performed at one time, and the usability is improved. Further, it becomes more convenient to load communication and recording functions as shown in FIGS. 26 (a) and 26 (b).

That is, as shown in FIG.
1 is a computer 45 for a medical institution such as a hospital through a communication port 42, a personal computer 43, a telephone line, and an antenna 44 for measuring a blood glucose level or the like measured by a blood sampling blood glucose meter 46 having a communication function.
26, or as shown in FIG. 26 (b), the measured value measured by the PC card recordable blood glucose meter 47 is
The data may be input to the home personal computer 43 via the C card 48 and printed out by the printer 49, or may be transferred to the medical institution computer 45.

[0072]

The blood collection method according to the first aspect of the present invention is a blood collection method in which the skin of a living body is punctured by a puncturing means, and the body fluid in the living body is exuded out of the body and collected. The punctured point is "depressurized and released."
, The effect of blood outflow can be increased by several steps, and a necessary amount of blood can be sufficiently collected from any part of the body in a short time, even with a shallow and narrow puncture.

In the blood collection method according to claim 1 of the present invention, the degree of pressure reduction is set between 15 kPa and 80 kPa. Is set in the above range, the symptoms can be prevented even at 40 kPa where congestion occurs when suction is normally performed continuously.

In the blood collecting method according to claim 1 or 2 of the present invention, the tip of the skin contact portion of the instrument or the vicinity thereof protrudes in the direction of the puncture point. In addition, the presence of the protruding portion ensures that the volume of blood vessels and blood around the puncture point that is blocked by the decompression is large, and that the skin that is raised by suction can be pressurized by the protruding portion, thereby enhancing the effect of blood outflow. be able to.

A blood collection method according to a fourth aspect of the present invention is a blood collection method in which the skin of a living body is punctured by a puncturing means, and a body fluid in the living body is exuded out of the body and collected. Pressurize, raise the skin near the puncture point with the puncture point,
Since the raised skin is sandwiched, blood is easily emitted.

In the blood collection method according to the fourth aspect of the present invention, the raised skin is brought closer to the skin contact portion of the device in the puncturing direction, so that blood is more easily discharged.

In the blood collection method according to the fifth aspect of the present invention, when the raised skin is sandwiched, the pressure applied to the skin is applied sequentially from the vicinity of the puncture point toward the puncture point.
The effect of squeezing out the blood near the puncture point further increases.

According to a sixth aspect of the present invention, there is provided a blood collection method according to the sixth aspect, wherein the skin is raised by an air bag attached to the tip of the skin contact portion of the device and inflated and contracted to a certain size by air pressure. Is even better.

According to the blood collecting method according to claim 4 of the present invention, the skin contact portion of the instrument is moved so that a force in the shear direction is applied to the puncture point on the skin.
Both the pressurizing effect and the squeezing effect can be applied to the skin near the puncture point, and the blood outflow effect is further improved.

A blood collection method according to a ninth aspect of the present invention is a blood collection method in which the skin of a living body is punctured by a puncturing means, and the body fluid in the living body is exuded out of the body and collected. The surrounding area is pressed, the skin near the puncture point is raised together with the puncture point, and the device contacts the skin and pressurizes the raised skin, so that blood can efficiently flow out from the puncture point.

According to a ninth aspect of the present invention, in the blood collecting method according to the ninth aspect, a cuff which is made of a flexible material such as a manchette and is inflated and contracted by air pressure is pressed around the puncture point, and the puncture point is reduced. At the same time, the skin near the puncture point is raised, so the air pressure is increased to expand the cuff to a certain volume, and the blood pressure of the skin raised from the puncture point made in a part of the cuff increases, thus increasing the blood outflow effect. Can be enhanced.

In the blood collecting method according to the tenth aspect of the present invention, since the cuff expands from the periphery of the puncture point toward the puncture point and presses around the puncture point, the entire cuff is simply performed at once. Rather than swelling, the air pressure increases from the outside to the puncture point around the puncture point so that blood is collected from the surrounding area toward the puncture point. Enhance.

In the blood collection method according to the ninth aspect of the present invention, when the raised skin is pressurized, the blood is pressurized from the outside of the puncture point toward the puncture point, so that the blood is directed toward the puncture point. The collected blood pressure in the vicinity of the puncture point is further increased, and a sufficient blood collection amount can be secured.

According to a ninth aspect of the present invention, there is provided the blood collection method according to the ninth aspect, wherein the air bag is attached to the tip of the skin contact portion of the instrument and inflated and contracted to a certain size by air pressure. Is raised and the raised skin is pressurized, so that the blood pressure can be increased while pressurizing the surrounding area toward the puncture point.

Claims 9 to 1 shown in claim 14 of the present invention.
In the blood collection method according to any one of the above, the skin contact portion of the instrument has at least two or more multi-cylindrical structures, and when pressed against the skin around the puncture point, the skin is sequentially moved from the outer cylinder toward the inner cylinder. Pressure is applied, and the skin near the puncture point is raised together with the puncture point and pressurized, so that the inner cylinder serves to collect blood toward the center (in the direction of the puncture point) with the blood stopped by the outer cylinder.

Claims 9 to 1 according to claim 15 of the present invention.
The blood collection method according to any one of the two, since the cylinder rotates at the time of pressurizing the tip of the cylindrical structure of the skin contact portion of the instrument, the skin is in a so-called squeezed state in conjunction with the rotation of the cylinder,
It has the effect of squeezing the blood that has been caught by the cylinder out of the body.

Claims 4 to 1 according to claim 16 of the present invention.
The blood collection method according to any one of (5) to (5), in addition to pinching around the puncture point on the skin and collecting blood pressure, reduces the pressure near the puncture point including the puncture point. Enhance.

Claims 4 to 1 according to claim 17 of the present invention.
5. The blood collection method according to any one of claims 5 to 5, wherein
Is repeatedly performed by a single operation, so that the effect of blood outflow can be very easily obtained by performing the operation with one operation of the user.

[Brief description of the drawings]

BRIEF DESCRIPTION OF THE DRAWINGS FIG. 1 shows the operation of a device for carrying out an embodiment of the blood collection method of the present invention, in which (a), (b) and (c) press the area around the puncture point from outside to inside using a device having a multi-cylindrical structure. FIG.

FIGS. 2A and 2B are explanatory diagrams illustrating a state in which the inner cylinder of the multiple cylinder is rotating together with the skin.

FIG. 3 is a perspective view showing a concavo-convex structure which is a skin contact portion of the rotating inner cylinder of the above.

FIG. 4 is a perspective view showing a state in which a protrusion protruding from an inner cylinder is rotating along a groove cut into the outer cylinder in the first embodiment.

FIGS. 5A and 5B are explanatory diagrams showing a state in which the periphery of the puncture point is pressed inward by the angle of the tip of the inner cylinder.

FIGS. 6A and 6B are explanatory views showing a state in which the tip of the inner cylinder is linearly angled.

FIGS. 7A and 7B are explanatory diagrams showing a state in which the tip of the inner cylinder is curved outward with an angle, and FIG. 7C is a view showing a state in which the curvature of the tip of the inner cylinder projects below horizontal. FIG.

FIGS. 8 (a), (b), (c), (d), and (e) are explanatory views showing a state where the vicinity of the puncture device is sandwiched by the device.

FIG. 9 is an explanatory diagram showing a state in which a wound due to puncture is opened by sandwiching the periphery of the puncture point.

FIG. 10 is an explanatory view seen from above of a state where the puncture point is sandwiched about the puncture point in the puncture point direction.

FIG. 11 is an explanatory diagram showing a state where pressure is applied to the puncture point in four directions from the four sides, as viewed from above.

FIG. 12 is an explanatory view showing a state in which a cuff having a puncture hole at a place to be a puncture point is wound around an arm;

FIG. 13 is an explanatory diagram showing a state in which the cuff is expanded from the outside of the puncture point to the inside by the injection of air.

FIGS. 14 (a), (b) and (c) are explanatory views showing a state in which a cuff wound around the entire forearm expands in order from the outside to the inside of the puncture point and pushes out blood in the direction of the puncture point. .

FIGS. 15 (a), (b), (c) and (d) are explanatory views showing a state in which a balloon attached to the distal end of the blood sampling device is inflated by air pressure and pressurizes around a puncture point.

16A is an explanatory view showing a state in which an inner pressurizing unit moves while closing or opening left and right along a groove cut outside, and FIG. It is explanatory drawing which shows a mode that it moves while closing and opening.

FIG. 17 is a graph showing a suction pattern in which the horizontal axis represents time and the vertical axis represents suction force, where (a) is a continuous pattern and (b)
Indicates an intermittent pattern, and (c) indicates an intermittent-continuous pattern.

FIGS. 18A and 18B show a protruding portion at the tip end, FIG.
(B) is a sectional view.

FIG. 19 is an explanatory view showing a state where the skin pulled up at the time of suction is automatically pressurized by the protrusion.

FIG. 20 is an explanatory diagram showing a state in which the pressure cylinder, the puncture needle, and the puncture needle fixing base are integrated.

FIG. 21 is a schematic cross-sectional view showing a state where a suction pump is further added to the blood collection device of FIG. 20;

FIG. 22 is an explanatory view showing a state in which the movable switch of the suction pump and the needle fixing base is automatically turned on and off by a finger using a leak valve switch.

FIG. 23 is an explanatory view showing the operation of the confirmation dome attached to the tip of the blood collection device of the above.

24 (a), (b) and (c) are explanatory views showing a state where the outer cylinder is connected to a suction switch and the inner cylinder is connected to a needle fixing base movable switch.

FIGS. 25 (a), (b), (c), and (d) are explanatory views showing a state where a cylinder existing near a needle presses the skin immediately before puncturing to puncture the skin.

26A is an explanatory diagram showing an operation of transferring a blood sampling value from a home to a hospital, and FIG. 26B is an explanatory diagram showing an operation of printing out the blood sampling value via a PC card or bringing the blood sampling value to a medical institution. is there.

[Explanation of symbols]

 1 skin 3 puncture point 4 outer cylinder 5 inner cylinder

Claims (17)

[Claims] 1. A blood sampling method for puncturing the skin of a living body with a puncturing means to exude body fluid in the living body to the outside of the body and collecting the blood. A blood collection method characterized by reducing the pressure while repeating "decompression and release". 2. The blood collection method according to claim 1, wherein the degree of pressure reduction is set between 15 kPa and 80 kPa. 3. The blood collection method according to claim 1, wherein the tip of the skin contact portion of the instrument or the vicinity thereof protrudes toward the puncture point. 4. A blood collection method in which the skin of a living body is punctured by a puncturing means, and bodily fluid in the living body is exuded out of the body and collected, wherein the area around the punctured puncturing point on the skin is pressurized, and the puncturing point and the puncturing point are combined. A blood collection method comprising raising nearby skin and sandwiching the raised skin. 5. The blood collection method according to claim 4, wherein the raised skin and the skin contact portion of the device are brought closer to each other in the puncturing direction. 6. The blood collection method according to claim 5, wherein, when the raised skin is sandwiched, pressure applied to the skin is applied in order from the puncture point to the puncture point. 7. The blood collection method according to claim 6, wherein the raised skin is sandwiched by an air bag attached to the tip of the skin contact portion of the device and inflated and contracted to a certain size by air pressure. 8. The blood collection method according to claim 4, wherein the skin contact portion of the instrument is moved so that a force in a shear direction is applied to a puncture point on the skin. 9. A blood collection method in which the skin of a living body is punctured by a puncturing means, and bodily fluid in the living body is exuded out of the body and collected, wherein the blood pressure is applied around the punctured puncturing point on the skin, and the puncturing point is pressed together with the puncturing point. A blood collection method, comprising raising the nearby skin, and pressing the raised skin by contacting the skin with an instrument. 10. A cuff that is made of a flexible material such as a manchette and is inflated and contracted by air pressure to press around the puncture point, and to raise the skin near the puncture point together with the puncture point. The blood collection method according to claim 9. 11. The blood collection method according to claim 10, wherein the cuff expands from around the puncture point toward the puncture point and presses around the puncture point. 12. The blood collection method according to claim 9, wherein, when pressurizing the raised skin, the pressure is applied from outside the puncture point toward the puncture point. 13. Raising the skin near the puncture point with an air bag attached to the tip of the skin contact portion of the device and inflating and contracting to a certain range by air pressure, and further pressurizing the raised skin. The blood collection method according to claim 9, wherein: 14. A skin contact portion of the instrument has at least two or more multi-cylinder structures, and when pressed against the skin around a puncture point, presses the skin toward the inner cylinder in order from the outer cylinder, and further punctures the skin. 13. The blood collection method according to claim 9, wherein the skin near the puncture point is raised together with the point and pressurized. 15. The blood collection method according to claim 9, wherein the cylinder is rotated when the distal end of the cylindrical structure of the skin contact portion of the device is pressurized. 16. The method according to claim 4, wherein in addition to pinching around the puncture point on the skin and collecting blood by pressurization, the pressure in the vicinity of the puncture point including the puncture point is reduced. Blood sampling method. 17. The blood collection method according to claim 4, wherein the operations in claims 4 to 15 are repeatedly performed by a single operation.