JP2002062300A - Automatic analyzer - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide an automatic analyzer capable of yielding a QC result without depending on a sample type and reducing a precision controlling load. SOLUTION: In response to a sample name 4 displayed on a measurement result display screen 1, a sample name 4 used for a quality control QC calculation is selected. The selected sample name 4 is displayed within a selection area 2. According to a measured value 5 in the selection area 2, the QC calculation is carried out and indicated by a QC calculation button 3. Among the measured values 5 in the selection area 2, identical items or all items are selected so as to be subjected to the QC calculation.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to an automatic analyzer provided with accuracy control means for measuring results.

[0002]

2. Description of the Related Art In an automatic analyzer according to the prior art, as one means for managing and maintaining the accuracy of measurement data of an automatic analyzer, a sample (control sample) having a known concentration is placed at a predetermined position on a sampler. The control sample is sampled and measured at a predetermined number of times periodically or when instructed. Then, these results are stored in a specific quality control (QC) memory or storage device.

[0003] The measurement results thus stored are samples with known concentrations (control samples), and all collected data are samples having the same concentration. Therefore, the stability of the measurement accuracy of the automatic analyzer can be confirmed by performing a statistical process such as an average value and a variance based on the measurement result and obtaining the result. Further, by recording these results every day, it is possible to confirm the measurement accuracy between the day differences of the apparatus.

In order to measure such QC data, it is necessary to prepare a control sample having a known specific concentration, set the measurement conditions, and secure a place for storing the measurement results.

FIG. 4 shows a flow of measurement by a conventional automatic analyzer. The flow of the process shown in FIG. 4 shows from the start of the measurement to the QC calculation for quality control and the display of the measurement result of the sample in the automatic analyzer. The measurement is started when the sample collected from the subject is set in the automatic analyzer. This measurement is performed according to a predetermined measurement item. When all the measurements are completed, the measured values for each measurement item are obtained, and the measurement database 7
After being stored in, this result is displayed as a number.

[0006] The display of the measured values is performed on a measurement result display screen of the display monitor 8. Here, the individual ID of the measured sample, the patient name, the measurement date, and the result display for each item are displayed in units of one line. If the user wants to check the detailed measurement result of a sample with a specific ID number, he can move the instruction cursor on the screen and press the keyboard to display the detailed measurement result of the sample.

[0007] In the list display, since a plurality of samples can be displayed collectively, the display is convenient for simultaneously selecting and deleting a plurality of samples and instructing the printing of the results. For example, if there is a suspicion of a measurement error in the data, it becomes necessary to pursue the cause. The cause may be the reagent used, or a defective part. Therefore, it is necessary to perform quality control (QC) of measurement data after assuming possible factors and taking appropriate measures.

Here, a control sample whose concentration is known in advance is measured. On the automatic analyzer side, the flow is divided depending on whether or not the sample to be measured is a control sample. Usually, control samples will be measured, but these are defined for normal test routines.

It is determined whether or not the data output from the measurement database 7 is control sample data. If the data is control sample data, it is used for quality control calculation. The calculation result after the quality control calculation is stored in the quality control database 6. Next, the calculation result output from the quality control database 6 is subjected to selection and display processing of the result of the quality control calculation, and is displayed on the display monitor 8.

In order to select and display all the results from the measurement database 7, the results are switched by the operator's selection and displayed on the display monitor 8.

[0011]

However, in the prior art, in order to perform statistical processing for managing the measurement accuracy of the automatic analyzer, considerable preparation is required in advance.
This includes preparing a control sample, setting measurement conditions for the control sample, and securing a storage location as QC data. If the operation for controlling the measurement accuracy is routine, once various conditions are set, the control sample is measured as a simple task. However, when a new evaluation is to be performed temporarily, for example, when the control sample is of a different type or when reagents or parts of the device are replaced, the control sample for QC must be defined and managed again. Data must not be mixed in the existing QC storage data area.

[0012] This is a troublesome work, and unnecessary data may be registered in the managed area. Returning this to the original state is also a troublesome work. In addition, when performing QC calculation, if the number of data increases, manual calculation is troublesome, and there is a concern that an error may occur.

[0013] Even in the measurement using the same control sample, if the data is to be checked before and after replacement due to a shortage of the sample, the automatic analyzer is temporarily stopped, and the QC data is calculated immediately before that. It is necessary to delete those measurement data so that new data can be entered, or to temporarily store all data and then temporarily delete data in the first half and the second half. It is burdensome to evaluate for each difference due to the measurement time and for changes in the surrounding environment (including component replacement).

According to the present invention, Q
It is an object of the present invention to provide an automatic analyzer capable of obtaining a C result and reducing the burden of quality control.

[0015]

According to the first aspect of the present invention, there is provided a measurement result storing means for storing a measurement result of each sample, and the measurement result is displayed for each sample. Measurement result display means, a selection means for selecting the displayed measurement results for each sample, and a calculation means for performing a quality control calculation on the measurement results between the same items in the plurality of selected samples. The feature of the automatic analyzer is the solution.

Further, according to the present invention as set forth in claim 2,
Measurement result storage means for storing the measurement results of each sample; measurement result display means for displaying the measurement results for each sample; selection means for selecting the displayed measurement results for each sample; And an operation means for performing a quality control operation on the measurement results between all items in the sample.

According to the third aspect of the present invention,
3. An automatic analyzer according to claim 1, further comprising a quality control result storage unit for storing a calculation result by said calculation unit.

Further, according to the present invention described in claim 4,
3. An automatic analyzer according to claim 1, further comprising a calculation result display means for displaying a calculation result by said calculation means.

Further, according to the present invention described in claim 5,
4. The automatic analysis device according to claim 3, wherein the quality control result storage means is capable of storing the designated operation result at a desired timing.

According to the present invention described in claim 6,
5. An automatic analyzer according to claim 4, further comprising a designating unit for designating a calculation result to be stored in said quality control result storage unit among calculation results displayed by said calculation result display unit.

[0021]

FIG. 1 is a diagram for explaining an automatic analyzer according to an embodiment of the present invention.
It is an example of the measurement result display screen 1 displayed on the automatic analyzer.

On the measurement result display screen 1, a sample name 4 displaying the name of a sample which is an object to be analyzed collected from a subject or the like, and measurement items set in advance for the sample displayed in the sample name 4 The measurement value 5 in which the measurement results in are displayed, and the sample name selected when selecting a sample for performing quality control (QC) calculation from the samples displayed in the sample name 4 are specified. A selection range 2 and a QC calculation button 3 for executing a QC calculation on the measured value of the sample specified and selected in the selection range 2 are displayed.

The result measured by the automatic analyzer of the present invention is managed and stored as a database so that a sample can be searched and the measurement result can be confirmed after the measurement operation is completed. To see what samples are available,
Alternatively, a list of contents stored for each sample in order to retrieve data of a desired sample is displayed. This list is displayed on the measurement result display screen 1, and the sample name is sample name 4.
And the measurement result of each sample is 5
Is displayed for each measurement item. A desired sample is searched for from the sample name 4 and the contents of the detailed measurement data can be referred to the measurement value displayed for each measurement item in the column of the measurement value 5.

A list is displayed on the measurement result display screen 1.
Further, in addition to the sample name 4, for example, a sample ID number, a patient name,
It is also possible to arrange measured dates, simple result values, and the like side by side on one line, and display them on a plurality of lines. By displaying in this manner, it is easy to grasp what sample is registered in the database, and it is easy to access the specified sample.

In order to control the QC of the automatic analyzer, a control sample having a known concentration is measured in advance, and the measurement result is subjected to statistical calculation processing to know the measurement accuracy. At the same time, the measurement accuracy is managed. I have. FIG. 2 shows one example of the QC result display displayed on the screen when the QC calculation button 3 is selected. The measurement results of the control sample are stored in a specific area for each type (often divided into high, medium, low, etc.). On the measurement result display screen 1, QC calculation can be performed for each of the measured values 5 for each of the divided control samples. By doing so, it is possible to easily instruct the QC calculation by pressing the QC calculation button 3 from the measurement result display screen 1 in which a list of the measurement data indispensable for searching the measurement data is displayed. After looking at the result of this QC calculation, data can be registered for QC processing.

The screen display of the automatic analyzer of the present invention referred to in FIGS.
An example is shown in which a sample is placed at the TAT position and measured six times without exchanging the sample. Of these measurements, select only 0002-0005 in the figure excluding the first and last,
A QC calculation button 3 displayed as simple QC in the figure is selected. With this operation, the QC calculation method is displayed on the screen, and "QC calculation using the same item data in the specified range", "QC calculation using all the item data in the specified range", and the like are selected. The calculation is executed according to this selection, the result is displayed on the screen, and it is also possible to print out as needed.

FIG. 3 shows the flow of measurement by the automatic analyzer of the present invention. In the automatic analyzer of the present invention, a control sample for QC is not particularly limited to a dedicated control sample, and a general sample can be used. In this case, after the collected measurement results are stored in the measurement database 11 in which the measurement data of the already measured sample is stored, the data is output as needed. Here, key input means 1
The data processing from the measurement database 11 changes depending on whether the operator selects the selection and display processing of all the results or the selection and display processing of the result of the quality control calculation via 3 or the like.

When selection and display processing of all results are selected,
In the measurement result display screen already shown in FIG. 1, it is possible to perform a quality control process of a result of a selected range and a menu selection of the display process. By this selection, either the entire result is displayed on the display monitor 12 or the quality control processing of the result in the selected range is displayed. Here, it is determined whether or not to register this result as quality management data. When registration is selected, the result is stored in the quality management database 10.

On the other hand, when the selection of the result of the quality control calculation and the display processing are selected, it is determined whether or not the output data from the measurement database 11 is control sample data. Here, if it is determined that the data is control sample data, it is determined whether or not the control sample is directly registered here.

When it is determined that the information is directly registered, a quality control calculation is performed, and the calculation result is stored in the quality control database 10.

By referring to the QC result obtained in this way, it is possible to easily grasp the quality of the measure against the data failure. These results are temporary and do not affect stored data registered as QC management.

Although the above has been described with reference to the example of the STAT, such an operation can be performed with a normal patient sample (sample).
For patient samples, the concentrations are usually different, but the range is limited. Therefore, referring to the measurement range or the like is also one method for confirming the state of the device. Conventionally, individual screens are created, but this is not a method that is used so frequently as compared with control QC processing. Therefore, even if such an operation screen is created, it is not used by all operators, and the number of development steps is increased and the cost of the apparatus is increased, which is disadvantageous.

However, the automatic analyzer according to the present invention does not cause such a problem because a sample can be arbitrarily selected. If the patient sample is arranged as the same sample, it is possible to perform QC management of the data according to the installation location of the patient sample and the like, and it is possible to manage and confirm the data accuracy with a fine grain.

According to the embodiment of the present invention described above, the sample for which the QC calculation is performed is not limited to the control sample, and the QC calculation is performed based on the list display for referring to the database storing the data from the past to the present. Freely select the sample you want to calculate, calculate QC statistics between the same items in the selected multiple samples (not limited to control samples) or between data of all items, and display on the screen can do. Also by specifying
Enable C registration management.

Further, since temporary QC processing can be realized and the type of sample is not limited, QC
There is no need to prepare operation screens and functions. Also, QC
I checked after registering in the storage area,
Operation can be simplified because data can be registered again after confirming whether or not to register. Even if you want to check the difference due to time or the difference before and after replacing the sample, you can easily select the result of the same control and check the result.

Further, QC calculation can be easily performed regardless of the type of sample (data statistical processing), and QC data can be easily obtained on an automatic analyzer, so that the quality of data under various conditions can be evaluated. You can check.

Further, without affecting the control QC data management, the QC processing can be performed after individually determining whether the data is correct (reliable) or not.

In addition, there is no need to create a dedicated QC operation screen for each sample, and, for example, it is possible to perform QC of a calibration sample or to perform QC processing only for re-examination.

Further, the difference before and after the control sample is replaced can be seen, and the difference in the measurement time can be confirmed. In this manner, QC processing can be performed under detailed conditions.

The embodiments described above are described for the purpose of facilitating the understanding of the present invention, and are not described for limiting the present invention. Therefore, each element disclosed in the above embodiment is intended to include all design changes and equivalents belonging to the technical scope of the present invention.

[0041]

According to the present invention, it is possible to provide an automatic analyzer capable of obtaining a QC result without depending on a sample type and reducing a burden of quality control.

[Brief description of the drawings]

FIG. 1 is a diagram illustrating a display of a measurement result of an automatic analyzer according to an embodiment of the present invention.

FIG. 2 is a diagram illustrating a display of a quality control calculation according to the embodiment of the present invention.

FIG. 3 is a diagram for explaining a processing flow of the automatic analyzer according to the embodiment of the present invention.

FIG. 4 is a diagram for explaining the flow of processing of a conventional automatic analyzer.

[Explanation of symbols]

DESCRIPTION OF SYMBOLS 1 ... Measurement result display screen, 2 ... Selection range, 3 ... QC calculation button, 4 ... Sample name, 5 ... Measurement value, 6 ... Information management database, 7 ... Measurement database, 8 ... Display monitor, 9 ... Key input device

Claims (6)

[Claims] A measurement result storage unit configured to store a measurement result of each sample; a measurement result display unit configured to display the measurement result for each sample; and a selection unit configured to select the displayed measurement result for each sample; An automatic analyzer comprising: an arithmetic unit configured to perform a quality control operation on a measurement result between the same items in the plurality of selected samples. 2. A measurement result storage unit for storing a measurement result of each sample, a measurement result display unit for displaying the measurement result for each sample, a selection unit for selecting the displayed measurement result for each sample, An automatic analyzer that includes an operation unit that performs an accuracy management operation on measurement results between all items in the selected plurality of samples. 3. The automatic analyzer according to claim 1, further comprising a quality control result storage unit that stores a calculation result obtained by said calculation unit. 4. The automatic analyzer according to claim 1, further comprising a calculation result display means for displaying a calculation result by said calculation means. 5. The automatic analyzer according to claim 3, wherein said quality control result storage means is capable of storing said specified calculation result at a desired timing. 6. The automatic analyzer according to claim 4, further comprising a designation unit that designates a calculation result to be stored in the quality control result storage unit among calculation results displayed by the calculation result display unit.