JP2001303437A - Itch preventing, antipruritic and antiflash fiber and method for producing the same - Google Patents

Abstract

PROBLEM TO BE SOLVED: To obtain a fiber having a function for suppressing generation of itching and inflammation after or during wearing at a site where fiber goods such as a corrective under wear and the like contact to the skin for a long time. SOLUTION: This itch-preventing, antipruritic and antiflash fiber carries a metal phthalocyanine derivative expressed by formula [I] (Wherein, R1 to R4 are each a different substituent; n1 to n4 are each the same as or different from one another and 1-4 a natural number; M is a metal selected from Fe, Co, Mn, Ti, V, Ni, Cu, Zn, Mo, W and Os) as an effective ingredient. Especially, R1 to R4 are each the same as or different from on another and a carboxy group, a sulfo group or an amino group and n1 to n4 are each the same as one another and 1 or 2.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a fiber used in direct contact with the skin, and more particularly to an antipruritic, antipruritic and anti-inflammatory fiber and a method for producing the same.

[0002]

2. Description of the Related Art In surgical treatment, when a cast or the like must be worn over a long period of time due to an injury such as a fracture,
Since it is not possible to take a bath or wipe the affected area with a cast, itching, irritation, and odor of the skin often occur due to sweat and waste products. This is based on the components of sweat and waste products, and bacteria grow and ferment to emit a bad smell, irritate the skin and make it feel itchy. This makes patients uncomfortable,
In addition, she feels pain and is a mental health problem. Similarly, when a compress is worn, itching and irritation may occur due to irritation to the skin. In order to improve the course of the treatment in such surgical treatment, it is conceivable to contact a diseased part with an antipruritic, antipruritic or anti-inflammatory function that eliminates offensive odor and suppresses the occurrence of itching and inflammation of the skin. Already, as a fiber cloth having such a function, the present inventors have proposed an antipruritic, antipruritic, fiber cloth with an anti-inflammatory agent in which an anti-inflammatory agent containing a metal phthalocyanine derivative as a main component is carried on the fiber as an active ingredient. It has been proposed (see Japanese Patent Application Laid-Open No. 5-58897). It is already known that this metal phthalocyanine derivative has a deodorizing effect (JP-A-56-63355).
Reference).

[0003]

On the other hand, there is a problem that itching or inflammation occurs during or after wearing on clothing, such as socks and rubber parts of underwear, where the clothing is in close contact with the skin. Underwear (bra, girdle,
All in one). This is because clothing adheres to the skin for a long time, so that sweat components remain on the skin surface, causing itching and inflammation of the skin. In the case of exercising while wearing sportswear, a supporter, or the like, a similar problem occurs because exercise promotes sweating. The present inventors have improved the fiber cloth carrying an anti-inflammatory agent containing the above-mentioned metal phthalocyanine derivative as a main component, solved the above problems, and established various conditions to complete the present invention.

[0004]

That is, the present invention provides a compound of the formula [I]

Embedded image (Wherein, in the formula [I], R _{1 to} R ₄ are the same or different substituents, n _{1 to} n ₄ are the same or different natural numbers of 1 to 4, M is F
e, Co, Mn, Ti, V, Ni, Cu, Zn, Mo, W, Os) metal phthalocyanine derivative represented by Fiber.

Further, the present invention relates to a compound of the formula [I]

Embedded image (Wherein, in the formula [I], R _{1 to} R ₄ are the same or different substituents, n _{1 to} n ₄ are the same or different natural numbers of 1 to 4, M is F
e, Co, Mn, Ti, V, Ni, a metal selected from Cu, Zn, Mo, W, Os) metal phthalocyanine derivative represented by It is a manufacturing method.

[0006]

Embodiments of the present invention will be described below. The method for producing the metal phthalocyanine derivative represented by the above formula [I] used in the present invention is already known as disclosed in the above-mentioned Japanese Patent Application Laid-Open No. 5-58897, and is described in detail. Although omitted, if one example is shown, iron phthalocyanine tetracarboxylic acid can be obtained as follows. Trimellitic anhydride, urea, ammonium molybdate, and ferric chloride anhydride are added to nitrobenzene, and the mixture is stirred, heated and refluxed to obtain a precipitate, and an alkali is added to the obtained precipitate to add water. It is decomposed and then made acidic by adding an acid.

It is preferable that a carboxyl group, a sulfonic acid group or an amino group be the same or different as the substituents R _{1 to} R ₄ in the formula [I]. Further, n _{1 to} n ₄ in the formula [I] are preferably the same 1 or 2. In the case of a sulfonic acid group, the amount of the sulfonic acid group carried on the fiber is more preferable than that of the carboxylic acid.

[0008] Other substituents include, for example, an alkyl group,
Substituent alkyl group (for example, chloromethyl group), halogen group, nitro group, azo group, thiocyanate group, carbonyl chloride group, carboxamide group, nitrile group, hydroxyl group, alkoxyl group, phenoxyl group, sulfonyl chloride group, sulfonamide group And thiol groups, alkylsilicon groups, vinyl groups, and the like, and furthermore, amine salts, quaternary ammonium groups, or salts thereof, pyridine groups and derivatives thereof, and salts thereof.

The central metal M in the formula [I] is Fe,
A metal selected from Co, Mn, Ti, V, Ni, Cu, Zn, Mo, W, and Os, of which Fe, Co, Mn, Ni, and Cu are particularly preferable.

The material of the fiber for supporting the metal phthalocyanine derivative may be any organic fiber such as natural fiber, synthetic fiber, regenerated fiber, semi-synthetic fiber, inorganic fiber, chitin and chitosan. In particular, cellulosic fibers, particularly cotton, are particularly preferable because they have good hygroscopicity, so that they absorb the sweat of the wearer well and have a synergistic effect on suppressing itching. Among the substituents, sulfonic acid groups and carboxylic acid groups are suitable for carrying on cotton, silk, wool, rayon and nylon, and amino groups are suitable for carrying on wool, silk and acrylic.

The above-mentioned fiber materials are described in detail. Natural fibers include cellulosic fibers such as cotton, hemp, hair of protein fibers, and silk, and synthetic fibers include polyamide fibers, polyester fibers, polyacrylic fibers, and polyurethane fibers. Regenerated fibers include rayon, semi-synthetic fibers include acetate, and inorganic fibers include glass fibers, ceramic fibers, metal fibers, and carbon fibers.

The shape of the fiber supporting the metal phthalocyanine derivative may be powder, short fiber, cotton, thread, cloth. Examples of the powdery material include wool powder, silk powder, chitin, chitosan and the like. For example, powdery chitin and chitosan are processed into a surgical suture or the like after carrying a metal phthalocyanine derivative.

The short fibers are preferably 0.2 to 0.5 mm long. For example, the short fibers of rayon carrying a metal phthalocyanine derivative are kneaded as a thickening raw material in creamy cosmetics (hair dressing, packs, etc.). And can be used by kneading it into a poultice base material or the like. Powders such as crystalline silk powder are used in a similar manner.

When the metal phthalocyanine derivative is supported on the flocculent fiber, a nonwoven fabric can be formed from this by a conventionally known method such as hydroentanglement. This nonwoven fabric is suitable for sanitary products and members for contacting the affected area such as dermatitis and athlete's foot with the skin.

[0015] Thread-like or cloth-like fibers carrying a metal phthalocyanine derivative are suitable for processing into gauze, underwear, supporters and the like. Specific examples of the cloth-like fiber include a woven fabric, a knitted fabric, a nonwoven fabric, a knitted fabric, and a paper leaf. In order to obtain a knit product, it is preferable to carry the knitted product on a cloth-like fiber rather than a thread-like fiber in terms of ease of processing. The short fiber can be obtained by finely cutting the filamentous fiber after supporting the metal phthalocyanine derivative.

These antipruritic, antipruritic and anti-inflammatory fibers may be covered with ordinary fibers or blended or woven with ordinary fibers. In addition, a metal phthalocyanine derivative can be supported on rayon obtained by previously kneading a protein component such as gelatin into a stock solution of spinning rayon and jetting it into a coagulation solution. In this case, gelatin can be included in 1-50% rayon. In addition, for example, it is also possible to prepare a fiber in which starch is previously supported on the surface of the fiber, and to carry the metal phthalocyanine derivative together with the starch. In addition to starch, alumina, ceramic powder such as cristobalite, activated carbon,
Examples include silica gel and zeolite.

As described above, after the fiber is loaded with the metal phthalocyanine derivative, the fiber is processed into a fiber product such as clothing or sanitary ware. However, after the fiber is processed into a fiber product, the metal phthalocyanine derivative is loaded. You can also.

The metal phthalocyanine derivative is supported on the fiber by means such as mixing, impregnation or coating. In order to carry the derivative on the fiber, it is preferable that the fiber is previously treated with a quaternary ammonium salt compound to be cationized. For example, the fiber thus cationized is immersed in an aqueous solution of a metal phthalocyanine derivative, and then dried in the shade to support the fiber.
Since the metal phthalocyanine derivative is firmly supported on the fiber, it can also function as a dye for the fiber.

The amount of the metal phthalocyanine derivative carried in the antipruritic, antipruritic and anti-inflammatory fiber of the present invention is 0.001.
If it is less than weight%, itching, antipruritic and anti-inflammatory effects are insufficient,
It is preferably 0.001% by weight or more. For example, when the metal phthalocyanine derivative is iron phthalocyanine tetrasulfonic acid and impregnated into a woven cotton fiber, it can be loaded up to about 0.5 to 10% by weight based on the weight of the fiber after loading.

The antipruritic, antipruritic and anti-inflammatory fibers of the present invention can be used in addition to the above-mentioned socks and underwear, as well as a variety of ordinary clothing such as sportswear such as spats, short spats, leotards and various supporters, stretch boots, and the like. Applicable to textile products such as tabi and hats. In addition to these ordinary clothes, sanitary goods include cloth diapers, disposable diapers, surfaces such as sanitary or obstetric napkins, and nursing care products such as underwear such as sleepwear and socks for patients, sheets, blanket covers, and pillow covers. It is also suitable for woven or knitted bandages, gauze, triangles, bandage covers, bandages, etc. for medical use. In this way, it can be applied to all textiles that may come into contact with the skin for a long time.

[0021]

According to the antipruritic, antipruritic and anti-inflammatory fiber of the present invention, it is possible to suppress the occurrence of itching and inflammation at the site where the fiber adheres to the skin for a long time by the active ingredient metal phthalocyanine derivative. Since it also has a deodorizing effect, it is possible to provide a fiber product that can be used comfortably by the user. Further, the present invention can be applied not only to cloth-like products but also to fibers used in other fields, such as hairdressing materials and cosmetic raw materials such as packs.

Continued on the front page (51) Int.Cl. ⁷ Identification symbol FI Theme coat II (Reference) // D06M 101: 00 D06M 101: 00 101: 02 101: 02 101: 06 101: 06 101: 14 101: 14 101: 16 101: 16 (72) Inventor, Wang Yoshi Shirai 2496 Nagase, Maruko-cho, Nagano Pref., Japan EE01 EE31A EE37A FF68 4C086 AA01 DA31 MA01 MA04 MA63 NA10 ZA89 ZB11 4L033 AA03 AB01 AC10 AC15 BA55

Claims (16)

[Claims] 1. A compound of the formula [I] (Wherein, in the formula [I], R _{1 to} R ₄ are the same or different substituents, n _{1 to} n ₄ are the same or different natural numbers of 1 to 4, M is F
e, a metal phthalocyanine derivative represented by Co, Mn, Ti, V, Ni, Cu, Zn, Mo, W, Os) supported on fibers as an active ingredient , Antipruritic, anti-inflammatory fibers. 2. In the above formula [I], R _{1 to} R ₄ are the same or different carboxyl group, sulfone group or amino group, n
₁ ~n ₄ is itching stop according to claim 1, wherein the same 1 or 2, antipruritic, anti-inflammatory fibers. 3. The pruritus according to claim 1, wherein the derivative is carried on the fiber by mixing, impregnation or application.
Antipruritic, anti-inflammatory fiber. 4. Material is natural fiber, synthetic fiber, regenerated fiber,
4. The antipruritic, antipruritic and anti-inflammatory fiber according to claim 1, which is a semi-synthetic fiber, an inorganic fiber, chitin or chitosan. 5. The antipruritic, antipruritic and anti-inflammatory fiber according to claim 1, wherein the fiber is in the form of powder, short fiber, cotton, thread or cloth. 6. The antipruritic, antipruritic and anti-inflammatory fiber according to claim 1, wherein the derivative is carried on a fiber containing a protein component. 7. The antipruritic, antipruritic, and antipruritic product according to claim 1, wherein the fiber is a fiber product that has been processed before carrying the derivative.
Anti-inflammatory fiber. 8. The antipruritic, antipruritic and anti-inflammatory fiber according to claim 1, which is processed into a fiber product after supporting the derivative. 9. A compound of the formula [I] (Wherein, in the formula [I], R _{1 to} R ₄ are the same or different substituents, n _{1 to} n ₄ are the same or different natural numbers of 1 to 4, M is F
e, Co, Mn, Ti, V, Ni, Cu, Zn, Mo, W, Os) metal phthalocyanine derivative represented by the formula , A method for producing anti-inflammatory fibers. 10. In the formula [I], R _{1 to} R ₄ are the same or different, a carboxyl group, a sulfone group or an amino group,
n ₁ ~n _{4 is} itching stop according to claim 9, wherein the same 1 or 2, antipruritic, method for producing antiphlogistic fibers. 11. The method for producing an antipruritic, antipruritic and anti-inflammatory fiber according to claim 9, wherein the derivative is supported on the fiber by mixing, impregnation or application. 12. The antipruritic, antipruritic and anti-inflammatory fiber according to claim 9, wherein the material of the fiber supporting the derivative is a natural fiber, a synthetic fiber, a regenerated fiber, a semi-synthetic fiber, an inorganic fiber, chitin or chitosan. Manufacturing method. 13. The fiber supporting the derivative may be in the form of powder, short fiber, cotton, thread, or cloth.
2. The method for producing the itchy, antipruritic and anti-inflammatory fiber according to 2. 14. The method for producing antipruritic, antipruritic and anti-inflammatory fibers according to claim 9, wherein the fiber contains a protein component in advance. 15. The antipruritic, antipruritic, and pruritus according to claim 9, wherein the derivative is carried after the fiber is processed into a fiber product.
Method for producing anti-inflammatory fiber. 16. The antipruritic, antipruritic, and pruritus according to claim 9, wherein the derivative is carried on a fiber and then processed into a fiber product.
Method for producing anti-inflammatory fiber.