JP2001247438A - Bleaching composition for tooth and bleaching set - Google Patents

Abstract

PROBLEM TO BE SOLVED: To obtain a bleaching composition capable of easily and surely removing stains firmly attached to the tooth and having excellent tooth bleaching effect. SOLUTION: The objective bleaching composition for tooth contains one or more salts selected from a straight-chain polyphosphoric acid salt expressed by the general formula Mn+2PnO3n+1 (M is Na or K; and n>=2) and a cyclic polyphosphoric acid salt expressed by the general formula (MPO3)m (M is Na or K; and m>=3) and further contains one or more compounds selected from citral, cinnamaldehyde, benzaldehyde, methyl salicylate, carvone, or the like. The tooth bleaching set contains the bleaching composition.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a whitening composition and a whitening set used for whitening teeth, and more particularly to food and drink, smoking, and coloring substances produced by oral bacteria. Whitening composition capable of effectively removing stains on teeth and whitening the teeth, and whitening the teeth by combining the composition with an application tool for holding and fixing the same to the teeth About the set.

[0002]

2. Description of the Related Art
Removal of coloring substances attached to the teeth is performed by using a dentifrice, toothbrush, and a physical method by polishing with a polishing component contained in the dentifrice, a chemical method using a solubilizing agent such as polyethylene glycol and polyvinylpyrrolidone, and peroxidation. Oxidation bleaching method etc. was carried out.

[0003] However, in such a case, it is difficult to completely remove the coloring material due to the difficulty of reaching the toothbrush between the teeth, the recessed portion of the meshing portion or the like, and the user's technique. In addition, there were many cases where the coloring substance fixed to the tooth surface could not be removed even by the abrasive component. In the case of (1), an effect is seen in coloring mainly composed of weak tobacco tar, but the effect on other colored substances is not sufficient. Furthermore, although it is performed in some dental clinics, there is a problem in safety, and it is difficult to perform it frequently in daily life.

[0004] Conventionally, the following method has been proposed as a method of chemically removing coloring matters on teeth, instead of physically removing the same with an abrasive. U.S. Pat. No. 3,988,433: Oral composition containing a specific organic peroxide U.S. Pat. No. 4,183,916: Oral composition using a combination of cationic surfactant and malic acid Japanese Patent Publication No. 48-43869: Aromatic Oral composition containing ring-containing ester JP-A-51-139,939: Oral composition containing a chelating agent having a stability coefficient of Fe> Ca JP-A-56-18911: Phytic acid Oral composition in combination with an organic acid JP-A-60-4117: Oral composition containing tartronic acid, glyceric acid, hydroxy-n-butyric acid or dihydroxymalonic acid JP-A-61-286315: Oral composition using carvone, anethole or 3-octanol in combination with a solvent extract of Astragalus plants No. 498: Oral composition blended with 2-octanol JP-A-62-181212: Oral composition blended with specific monoterpene JP-A-62-189233: Total carbon number of 7 to 11 Oral composition containing aliphatic ester

[0005] Further, as a method of chemically removing a coloring substance of teeth by blending a polyphosphate, the following proposal has been made. JP-A-52-108029: Oral composition using a combination of polyphosphate and polyvalent metal cation JP-A-1-250312: Oral composition containing an aldehyde compound having 7 to 9 carbon atoms and a polyphosphate Japanese Patent Application Laid-Open No. 7-10726: A composition for oral cavity containing no polisher using a combination of a citrate, a water-soluble polyphosphate and a nonionic surfactant having an HLB of 7 to 14. Gazette: Oral composition for chemically cleaning dental stains using a combination of polyphosphate, orthophosphate and amphoteric surfactant JP 9-12438A: Polyphosphate, orthophosphate and alkyl sulfate Oral composition for chemically cleaning dental stains in combination with salt JP 9-175966 A: Chemically cleaning dental stains in combination with pyrophosphate + polyphosphate (P ≧ 3) You Oral composition Japanese Patent Publication No. 9-501679: Composition for whitening teeth using a sequestering agent and a reducing agent in combination Japanese Patent Publication No. 9-507481: 5-15% of water-soluble alkali metal tripolyphosphate Tooth whitening composition blended Japanese Patent Application Laid-Open No. 10-182386: A composition for oral cavity for chemically cleaning tooth stains using a combination of polyphosphate and water-insoluble scrub particles derived from animals and plants

[0006] However, these methods often cannot sufficiently remove stubborn stains deposited on the tooth surface due to poor long-term oral cleaning.

Further, a preparation in which a sequestering agent containing polyphosphate alone or a sequestering agent containing polyphosphate and a reducing agent are applied to teeth of appliques, mouthpieces and the like and left for several hours together with a coating for secure fixation. A product has also been proposed (Japanese Patent Publication No. 9-501679, Japanese Patent Publication No. 9-5074).
No. 81). However, in the case of polyphosphate alone or in combination with a reducing agent, the polyphosphate penetrates the stain layer,
In many cases, the transmission power is weak and the effect cannot be sufficiently exhibited.

An object of the present invention is to provide a tooth whitening composition and a whitening set capable of easily and surely removing a coloring substance attached to a tooth, in which the above circumstances have been improved. .

[0009]

[Embodiment of the means and invention to solve the Problems The present inventor has conducted extensive investigations to achieve the above objects, the following general formula _{(1) M n + 2 P} n O 3n + 1 ... (1) (where M represents Na or K, and n ≧ 2) and a linear polyphosphate represented by the following general formula (2) (MPO ₃ ) _m (2) , M represents Na or K, and m ≧ 3.) And at least one selected from cyclic polyphosphates, and citral, cinnamaldehyde, benzaldehyde, methyl salicylate, Carvone, citral dimethyl acetal, citral diethyl acetal, citral propylene glycol acetal, heptyl aldehyde, octyl aldehyde, anis aldehyde, ethyl hexyl aldehyde, nonyl alde De, GEOS phenol, Ferrand Doral, Karubomenton, thymoquinone, chrysanthenone, krypton,
Tuyeon, Fencon, Piclocrocin, Santenone, α
-Use of a composition containing one or more compounds selected from ionone, β-ionone, α-iron, hinokitiol, α-shinepurine, γ-shinepurine and artemisia ketone, in this case more preferably By using this composition in combination with a tool for holding and fixing to teeth without being diluted by saliva or the like in the mouth or removed by mechanical force such as occlusion or mastication,
It has been found that it has a high effect of peeling off and removing colored substances (tea astringent, tobacco stain, etc.) on teeth and is excellent in whitening teeth.

That is, the present inventor has found that by using the above-mentioned specific compound in combination with the above-mentioned polyphosphate, the stain permeability of the polyphosphate is greatly increased. Furthermore, this composition exerts a stain removing effect as the time applied to the tooth is longer, but toothpaste, water toothpaste, liquid toothpaste, mouthwash which has been proposed as a normal oral composition dosage form In such dosage forms, the composition is not diluted in the mouth and
It is difficult to hold for longer than 0 seconds. Further, as a dosage form for applying the composition directly to the teeth and holding the same, dental creams, gels, and the like have been proposed,
It is difficult to sufficiently retain the tooth by dilution or washing of the composition with saliva, and a composition using the above polyphosphate and a specific compound in combination, and retaining this composition on the tooth,
By combining with a dedicated tool that can be fixed, the present inventors have found a usage that has a higher stain removing effect and makes the teeth whiter and more beautiful, and has accomplished the present invention.

Hereinafter, the present invention will be described in more detail. The tooth whitening composition of the present invention is prepared by preparing a composition containing a whitening component in the form of a liquid, paste, gel, foam, or powder. . More preferably, this can be reliably applied and fixed to the teeth, and in order to prevent the composition from being diluted by saliva or the like during use, or from being removed from the teeth by mechanical force such as occlusion, mastication, or brushing. Applied as a whitening set together with the special application tool.

[0012] whitening ingredients to be blended in the whitening composition as the (first component), the following general formula _{(1) M n + 2 P} n O 3n + 1 ... (1) ( where, M is Na or K Wherein n ≧ 2), that is, sodium pyrophosphate or potassium pyrophosphate having a polymerization degree of n = 2, sodium tripolyphosphate or potassium tripolyphosphate having n = 3, and sodium tetrapolyphosphate having n = 4. And linear polyphosphates such as sodium tetraphosphate and potassium metaphosphate having a high degree of polymerization, and the following general formula (2) (MPO ₃ ) _m (2) (where M is Na or K, m ≧ 3), that is, sodium trimetaphosphate or potassium trimetaphosphate having a polymerization degree m = 3, sodium tetrametaphosphate or tetrametaphosphate having m = 4. Um, cyclic polyphosphates, such as sodium hexametaphosphate and potassium hexametaphosphate m = 6 is used. These polyphosphates may be used alone or in combination of two or more. Among them, linear polyphosphates are preferable, and those having a polymerization degree of 2 ≦ n ≦ 50 are particularly preferable. More preferred.

In this case, the amount of the polyphosphate is as follows:
It is preferably 0.1 to 20% (mass percentage, the same applies hereinafter), preferably 0.5 to 15%, particularly preferably 1 to 10% in the composition. If the amount is too small, the effect of removing dirt is not sufficiently exhibited, and if the amount is too large, it may not be uniformly dissolved in the preparation, or even if used in combination with the tool, an unpleasant flavor accompanied by a small amount of elution may be felt. is there.

Specific compounds (second component) used in combination with the polyphosphate include citral, cinnamaldehyde, benzaldehyde, methyl salicylate,
Carvone, citral dimethyl acetal, citral diethyl acetal, citral propylene glycol acetal, heptyl aldehyde, octyl aldehyde, anisaldehyde, ethyl hexyl aldehyde, nonyl aldehyde, diosphenol, ferrandal, carbomentone, thymoquinone, chrysanthenone, krypton, thuyon, fencon, picrocrocin , Santenone, α-ionone, β-ionone, α-iron, hinokitiol, α-shinepurine, γ-shinepurine and artemisia ketone are used. These can be used alone or in combination of two or more.

In this case, citral, cinnamaldehyde, benzaldehyde, methyl salicylate and carvone have excellent whitening effect and are preferably used.

The amount of the compound (second component) is 0.001 to 15% in the composition, preferably 0.005 to 10%.
%, Particularly preferably 0.01 to 5%. If too little,
If the effect of penetrating the polyphosphate into the stain is weak, the effect of removing dirt is not sufficiently exhibited, and if too much, unpleasant feeling of use and irritation of the mucous membrane associated with a small amount of elution even with the use of tools There is.

In the whitening composition of the present invention, in addition to the above-described components, a component that further enhances the stain permeability of the polyphosphate may be used in combination, and further, an appropriate component according to the form or the like may be blended. Can be. For example, an anionic surfactant and / or a lower alcohol having 3 or less carbon atoms can be blended as a component that enhances the stain permeability of the polyphosphate.

In this case, examples of the anionic surfactant include sodium alkyl sulfates such as sodium lauryl sulfate, sodium myristyl sulfate and sodium cetyl sulfate; sodium N-acyl glutamates such as sodium N-lauroyl glutamate and sodium N-palmitoyl glutamate; N-lauroyl sarcosine sodium, N-myristoyl sarcosine sodium and the like
Sodium N-methyl-N-acyltaurine, sodium N-methyl-N-acylalanine, such as sodium acylsarcosine, sodium N-lauroylmethyltaurine, sodium N-myristoylmethyltaurine,
Sodium laurylbenzenesulfonate, hydrogenated coconut fatty acid sodium monoglyceride monosulfate, sodium lauryl sulfoacetate, sodium α-olefin sulfonate, sodium lauryl POE sulfate, sodium lauryl POE acetate, sodium lauryl POE phosphate, sodium stearyl POE phosphate, etc. Used
Among them, sodium alkyl sulfate, sodium N-acylglutamate, sodium N-acylsarcosine, sodium N-methyl-N-acyltaurine, N-
Sodium methyl-N-acylalanine is preferably used.

The amount of the above-mentioned surfactant to be added is 0.1% in the composition.
01-20%, desirably 0.05-10% is suitable. If the amount is too small, the effect of penetrating the polyphosphate into the stain is weak, and the effect of removing dirt is not sufficiently exhibited. May cause irritation.

As the lower alcohol having 3 or less carbon atoms, methyl alcohol, ethyl alcohol, and propyl alcohol are used, and ethyl alcohol or propyl alcohol is particularly preferably used.

The amount of the lower alcohol is 0.05 to 40%, preferably 0.5 to 30%, in the composition. If the amount is too small, the effect of penetrating the polyphosphate into the stain is weak, and the effect of removing dirt is not sufficiently exhibited.
If the amount is too large, the polyphosphate may not be dissolved, and the preparation may become non-uniform, or even if a tool is used in combination, an unpleasant feeling of use or irritation may occur on the mucous membrane due to a slight amount of elution.

In the present invention, the above-mentioned anionic surfactant, polyphosphate and the above-mentioned specific compound may be used in combination, and the lower alcohol having 3 or less carbon atoms and the polyphosphate and the above-mentioned specific compound may be used in combination. Alternatively, an anionic surfactant and a lower alcohol having 3 or less carbon atoms may be used in combination with the polyphosphate and the specific compound.

[0023] The whitening composition of the present invention may be, for example, gelled or pasted to improve the applicability to teeth,
Alternatively, various gelling agents are used for the purpose of increasing the adhesion to teeth. As the gelling agent, hydroxyethylcellulose, sodium carboxymethylcellulose, cellulose derivatives such as methylcellulose, sodium alginate, carrageenan, xanthan gum, gum tragacanth, karaya gum, gum arabic, gellan gum, native gellan gum, polyvinyl alcohol, sodium polyacrylate, One or more kinds of synthetic binders such as carboxyvinyl polymer, polyvinylpyrrolidone and polyethylene oxide, and inorganic binders such as silica gel, aluminum silica gel, veegum and laponite may be blended.

In this case, hydroxyethyl cellulose, sodium carboxymethyl cellulose, sodium alginate, carrageenan, xanthan gum, native gellan gum, polyvinyl alcohol, and carboxyvinyl polymer are preferred as gelling agents which are less sticky and dissolve in the mouth and are excellent in usability. Used for Particularly, hydroxyethyl cellulose, sodium carboxymethyl cellulose, sodium alginate, carrageenan, xanthan gum, and carboxyvinyl polymer are desirable.

When the above-mentioned gelling agent is blended, the amount of the gelling agent is particularly determined when the tool used in combination is a tape, sheet or dentition cover, and the whitening composition adheres to the teeth alone.
Since it is necessary to be able to fix, 0.1 to 15% is suitable, and especially 0.5 to 10% is desirable. If too little,
Adhesive strength is not exhibited, and it is difficult to use together with a tape, a sheet, or a dentition cover. If the amount is too large, the gelling agent may not be sufficiently dissolved and the preparation may be non-uniform.

Further, while preventing the whitening composition from drying,
For the purpose of enhancing the usability, one or more of humectant such as sorbit, glycerin, ethylene glycol, propylene glycol, 1,3-butylene glycol, polyethylene glycol, polypropylene glycol, xylitol, maltitol, lactitol are blended. I can do it.

In addition to the anionic surfactant, one or more of a nonionic surfactant and an amphoteric surfactant can be used in combination as the surfactant.

In this case, as the nonionic surfactant,
Glycerin fatty acid esters such as monoglyceryl stearate and decaglyceryl laurate; sugar fatty acid esters such as sucrose fatty acid ester, maltose fatty acid ester; lactose fatty acid ester; sugar alcohol fatty acid esters such as maltitol fatty acid ester and lactitol fatty acid ester; Ethylene sorbitan monolaurate, polyoxyethylene sorbitan fatty acid ester such as polyoxyethylene sorbitan monostearate, polyoxyethylene fatty acid ester such as polyoxyethylene hydrogenated castor oil, fatty acid ethanolamide such as myristic mono- or diethanolamide, sorbitan fatty acid Ester, polyoxyethylene higher alcohol ether, polyoxyethylene polyoxypropylene copolymer, polio Shi polyoxypropylene fatty acid ester or the like is used.

Examples of the amphoteric surfactant include N-lauryldimethylaminoacetate betaine and other alkyldimethylaminoacetate betaines, N-lauryldiaminoethylglycine and N-myristyldiaminoethylglycine.
Alkyldiaminoethylglycine, N-alkyl-N-
Carboxymethylammonium betaine, 2-alkyl-1-hydroxyethylimidazoline betaine sodium and the like are used.

Further, in the present invention, as active ingredients, enzymes such as dextranase, mutanase, lysozyme, amylase, protease, lytic enzyme, superoxide dismutase, and alkali such as sodium monofluorophosphate and potassium monofluorophosphate are used. Fluorine compounds such as metal monofluorophosphate and sodium fluoride, polyethylene glycol, polyvinylpyrrolidone, allantoin, dihydrocholestanol, glycyrrhizic acids, glycyrrhetinic acid, ε-aminocaproic acid, tranexamic acid, bisabolol, isopropylmethylphenol, sodium chloride, triclosan , Chlorhexidine salts, cetylpyridinium chloride, benzethonium chloride, benzalkonium chloride, ascorbic acid and its salts, toco Eroru, Scutellaria, Oobaku,
One or more active ingredients such as crude drug extracts such as rosemary, clove, and thyme may be blended.

The whitening composition of the present invention further comprises a fragrance such as menthol, anethole, peppermint oil, a preservative such as benzoic acid and its sodium salt, parabens, Red No. 3, Red No. 104 and Yellow No. 4. , Blue No. 1, Green 3
And a coloring agent such as titanium oxide, mica titanium and red iron oxide, and a sweetener such as saccharin sodium, stevioside, glycyrrhizin, aspartame and the like.

Further, the whitening composition of the present invention can be used as a dentifrice by brushing as it is. When used as such a dentifrice, it is preferable to mix an abrasive that does not release polyvalent metal ions such as calcium ions as the abrasive. Examples of such an abrasive include silicic anhydride, aluminum silicate, zirconium silicate, insoluble sodium metaphosphate, bentonite, aluminum hydroxide, alumina, titanium oxide, crystalline cellulose, polymethyl methacrylate, and other synthetic resins. And one or more of these are used.

Brushing the stain with a dentifrice containing an abrasive before the application of the whitening composition is particularly effective since the penetration of the polyphosphate into the stain in the whitening composition is further promoted. This is a preferred use. In this case, the component of the dentifrice is not specified as long as the abrasive is contained, but by mixing the above-mentioned abrasive into the whitening composition, the dentifrice may also be used by the whitening composition. it can.

The pH of the whitening composition is not particularly limited as long as there is no problem in the oral cavity and the human body in terms of safety, but the pH is preferably 5.5 to 9. As a pH adjuster, hydrochloric acid, sulfuric acid, nitric acid, citric acid, phosphoric acid, sodium hydroxide, potassium hydroxide, sodium carbonate, sodium citrate, sodium hydrogen citrate, sodium phosphate, sodium hydrogen phosphate, etc. obtain.

An application tool for holding and fixing to teeth, which is used in combination with the whitening composition of the present invention, assists in reliably applying and fixing the whitening composition to teeth, Suppresses dissolution of the composition into the gingiva, tongue, and oral mucosa, prevents unpleasant feeling of use and induces saliva, further dilutes the composition due to saliva intrusion, occlusion, chewing, and other physical stimuli, and withdraws from the teeth Used to prevent The material and shape of the tool are not particularly limited as long as the object can be achieved, but tapes, sheets, films, dental trays, mouth trays made of a water-insoluble material,
A mouthpiece, a sponge, an impression material, a pack material, a tooth cover molded into a row of teeth, a chewing brush having a large number of projections on a tooth contact surface formed into a row of teeth, and the like are preferably used.

With respect to the above-mentioned device, the surface of the surface in contact with the oral mucosa and the tongue is made of a material having high hydrophilicity and high water absorbency, for example, woven or non-woven fabric using rayon, pulp, cotton, silk, paper or the like. Since it absorbs and retains saliva generated in the mouth, it has an excellent feeling in use and is preferable. in this case,
By combining a water-impermeable film such as polyethylene, polypropylene, or polyester on the side that holds the whitening composition, it is possible to prevent the whitening composition from adsorbing and penetrating into the application tool.

On the other hand, plastic resins such as silicone rubber and natural rubber, vinyl acetate resins, acrylic resins, ethylene-
Trays made of thermoplastic resin such as vinyl acetate copolymer,
Mouthpieces and chewing brushes have a high degree of freedom in deformation and are easy to fit into the user's dentition and tooth type.
It has excellent adhesion and fixation properties, and is suitable for the purpose of applying the whitening composition to teeth for a longer time.

Further, when a liquid or a composition having a low viscosity and low adhesiveness to teeth is used in combination, a sponge impregnated with the preparation or a water-absorbing resin such as rayon, cotton, or pulp is used for the tooth. An appropriate amount of the composition can also be applied to the tooth by laying it inside the cover, tray or the like and continuing to bite it.

The whitening composition of the present invention comprises the above-mentioned linear polyphosphate of the general formula (1) and / or the general formula (2)
Cyclic polyphosphate and the above specific compound (second component)
Is applied to the teeth as they are, or brushing is performed as a dentifrice.

Further, more preferably, as a tooth whitening set, the above-mentioned whitening composition is applied to a tooth for a long time in combination with an application tool capable of securely holding and fixing the tooth, and then removed and washed with water. More preferably, after removal, the whitening composition is brushed with a toothbrush or the like while adhering to the teeth, thereby improving the ability to remove stains adhered to the teeth, in particular, tannin and coloring matter derived from tobacco tar. In particular, the stain removal effect of the polyphosphate in the present invention is based on the effect that the polyphosphate dissolves, polishes, or decolorizes the stain from the surface layer, and the polyphosphate penetrates and penetrates the stain layer to reach the enamel of the tooth surface layer. In addition, the bond between the stain and the enamel is weakened, and the stain is peeled from the tooth surface layer, thereby exhibiting a high removal effect.

The tooth whitening set of the present invention is prepared by pasting, dipping, adhering, pressing, spraying, applying, and applying a whitening composition in advance.
A method in which the composition is fixed to the tool by burial or the like so that it can be worn on the tooth as it is, a composition for whitening and a tool are separately prepared, and the composition is fixed to the tool at the time of use and then worn on the tooth, a method for whitening The object can be achieved in any of the methods in which the composition is applied to the teeth and then coated with the tool.

[0042]

EXAMPLES Hereinafter, the present invention will be described in detail with reference to Examples and Comparative Examples, but the present invention is not limited to the following Examples. In addition, all% in each example is a mass percentage.

Examples 1-4 and Comparative Example 1 A whitening composition having the composition shown in Table 1 was prepared, and the ability to remove coloring matter fixed to the teeth was evaluated by the following method.

[0044]

[Table 1]

Selection of Stain Removal Test Panel for Fixing Human Teeth and Evaluation Method of Stain Adhesion Out of four maxillary anterior teeth, at least one of the teeth has brown-black-brown stains which are considered to be derived from tobacco tar. 35 smokers were sorted into panels, brushed with their own method using a commercially available dentifrice in advance, and it was confirmed that the stains could not be removed. These teeth were evaluated. The number of target teeth per person was limited to one). The above-mentioned target tooth is divided into four tooth surfaces as shown in FIG. 1, and the area of the colored stain (stain) attached to each tooth surface and the density of the color tone are visually determined. Scored based on:

[0046]

[Table 2]

After the evaluation, the panels were divided into seven groups of five persons so that the stain adhesion level was equal, and the panels were divided into test group 1, test group 2, test group 3, test group 4, test group 5, and test group 5, respectively.
Comparative group 1 and comparative group 2 were set.

Formulations and Methods of Use The panels of Test Groups 1 to 5 and Comparative Groups 1 and 2 were prepared using the compositions shown in Table 3 and designated for use (usage of a or b).
Used in. (A) Toothpaste application: Apply the composition to a commercially available toothbrush,
Brush for 0 seconds. (B) Mouthpiece usage: The composition was poured into a silicone rubber mouthpiece for anterior teeth coating, which was added to the anterior teeth and applied to the teeth for 3 minutes, and then the mouthpiece was removed.
Brush for 30 seconds with a commercially available toothbrush.

[0049]

[Table 3]

Results The stain removal rate was calculated from the stain score before and after cleaning based on the following equation. The results obtained when the composition for whitening of Example 1 was used in the toothpaste method were tested in Test Group 1 (and a comparison with Comparative Group 1), and the results obtained by operating the same composition in a soaking method with a mouthpiece were tested. The results are shown in Group 2 (and a comparison with Comparative Group 2). Each of the whitening compositions of Examples 2, 3, and 4 was operated only by the mouthpiece method (test groups 3, 4, and 5).
5) and the comparison with Comparative Group 2. Stain reduction rate (%) = (Score before cleaning−Score after cleaning) / Score before cleaning × 100

[0051]

[Table 4] Stain removal effect ：: 80% or more ：: 60 to 79% Δ: 40 to 59% ×: 39% or less

[0052]

[Table 5] Stain removal effect ：: 80% or more ：: 60 to 79% Δ: 40 to 59% ×: 39% or less

From the results shown in Tables 4 and 5, it was confirmed that the use of the whitening composition containing the polyphosphate and the specific compound (second component) of the present invention has a high stain removing effect. .

Example 5 A sponge incised in the form of a tooth impregnated with the following liquid composition 5 (sponge is inserted into the tooth as it is, or the sponge is bitten and applied) Whitening composition 5 (liquid) Sodium tripolyphosphate 0.1% Cinamic aldehyde 0.1 N-lauroyl sarcosine sodium 1.0 Ethanol 30.0 Propylene glycol 2.0 Glycerin 10.0 Saccharin sodium 0.01 Blue No. 0.0002 Perfume (the second component Not included) 1.0 5N hydrochloric acid (pH adjuster) Appropriate amount of purified water Balance meter 100.0%

[Example 6] Rayon nonwoven fabric tooth type cover impregnated with the following liquid composition 6 (the cover is applied to the tooth as it is) Whitening composition 6 (liquid) Sodium tripolyphosphate 3.0% Tsuyon 0.05 Sodium lauryl sulfate 2.5 N-Lauroyl sarcosine sodium 0.5 Sorbit 15.0 Sodium fluoride 0.22 Saccharin sodium 0.01 Fragrance (excluding the second component) 1.0 5N hydrochloric acid (pH adjuster) Appropriate amount of purified water Balance meter 100.0%

Example 7 Rayon nonwoven fabric sheet impregnated with the following liquid composition 7 (applying the sheet as it is to the tooth) Whitening composition 7 (liquid) Sodium tripolyphosphate 7.0% pyrophosphoric acid Sodium 1.0 Methyl salicylate 0.3 Sodium lauryl sulfate 0.01 Ethanol 15.0 Propyl alcohol 5.0 Saccharin sodium 0.02 Fragrance (excluding second component) 1.0 5N hydrochloric acid (pH adjuster, pH 8.5) Adjusted to the appropriate amount) Purified water balance meter 100.0%

[Example 8] Combination of the following liquid composition 8 and a mouse tray with cotton balls laid inside (impregnated with a liquid composition when used, swab the tray and apply when using) Whitening composition Product 8 (Liquid) Sodium Tripolyphosphate 5.0% Citral 0.01 Sodium Lauryl Sulfate 2.0 Ethanol 8.0 Saccharin Sodium 0.01 Flavor (excluding the second component) 1.0 5N hydrochloric acid (pH adjuster) Appropriate amount Purified water balance meter 100.0%

Example 9 Combination of the following foam composition 9 and a silicone rubber mouse tray (the foam composition is put on the mouse tray at the time of use and applied by biting) Whitening composition 9 (foam Sodium tripolyphosphate 3.0% Potassium tripolyphosphate 1.0 Fencon 0.02 Sodium N-lauroylglutamine 0.02 Sodium N-lauroylmethyltaurine 0.03 Ethanol 0.5 Polyoxyethylene (60) hydrogenated castor oil 3 Polyvinylpyrrolidone 1.0 Saccharin sodium 0.1 Fragrance (not including second component) 1.0 5N hydrochloric acid (pH adjuster) Appropriate amount Purified water Balance meter 100.0%

Example 10 Combination of the following foam composition 10 and a mouthpiece made of a thermoplastic ethylene-vinyl acetate copolymer to be molded into an individual tooth mold (the foam composition was used at the time of use) The composition for whitening 10 (foam) potassium pyrophosphate 0.5% sodium metaphosphate (P chain = 40) 0.5 α-ionone 0.005 N-lauroylglutamine sodium 5.0 Ethanol 3.0 Sodium carboxymethylcellulose 1.0 Polyethylene glycol 5.0 Saccharin sodium 0.1 Fragrance (excluding second component) 0.5 5N hydrochloric acid (pH adjuster) Appropriate amount Purified water Balance meter 100.0%

Example 11 The following paste-like composition 11
And a water-insoluble acrylic tooth pack material (paste composition is applied to teeth at the time of use, and then the pack material is overcoated to form a coating thereon) and applied to whitening composition 11 (paste form) Sodium pyrophosphate 1.0% Citral diethyl acetal 3.0 Propylene glycol 3.0 Glycerin 10.0 Sorbit 10.0 Xanthan gum 2.0 Saccharin sodium 0.01 5N hydrochloric acid (pH adjuster) Appropriate amount Purified water Balance meter 100.0%

Example 12 The following paste-like composition 12
(A paste-like composition is applied to teeth at the time of use, and coated with a film sheet from above, and applied). Whitening composition 12 (paste-like) Sodium tripolyphosphate 4.0% Citral propylene glycol acetal 0.1 Sodium lauryl sulfate 2.0 Ethanol 10.0 Hydroxyethyl cellulose 3.0 Saccharin sodium 0.01 Fragrance (excluding second component) 0.9 5N hydrochloric acid (pH adjuster) Appropriate amount Purified water Balance meter 100.0%

Example 13 A natural rubber chewing brush in which the following gel composition 13 was embedded (applied by biting the chewing brush with teeth as it is) Whitening composition 13 (gel) Sodium metaphosphate (P chain) = 14) 5.0% Carvone 0.5 Sodium lauryl sulfate 2.5 N-Lauroyl sarcosine sodium 0.5 Sodium lauryl phosphate 0.3 Ethanol 7.0 Propyl alcohol 3.0 Glycerin 20.0 Carrageenan 5.0 Saccharin sodium 0.01 5N hydrochloric acid (pH adjuster) Appropriate amount Purified water Balance meter 100.0%

Example 14 Rayon / polypropylene tooth sticking sheet using the following gel composition 14 as an adhesive layer (applying the sheet as it is to the tooth) Whitening composition 14 (gel) Sodium tripolyphosphate 5.0% Citral 0.3 Sodium lauryl sulfate 2.0 Ethanol 8.0 Sorbit 30.0 Hydroxyethylcellulose 4.5 Sodium alginate 2.5 Saccharin sodium 0.02 Fragrance (excluding second component) 0.7 5N hydrochloric acid (PH adjuster) Appropriate amount of purified water Balance meter 100.0%

Example 15 Clay-like alginate impression material kneaded with the following powdery composition 15 (applying the impression material with teeth as it is) Whitening composition 15 (powder) Sodium tripolyphosphate 0% sodium pyrophosphate 3.0 sodium hexametaphosphate (cyclic) 2.0 benzaldehyde 0.001 stevioside 0.1 powdered flavor (not including the second component) 3.0 powdered ethanol (ethanol content: 30%) Balance meter 100 0.0%

Example 16 Toothpaste-like composition 16 Whitening composition 16 (paste) Sodium tripolyphosphate 5.0% Sodium pyrophosphate 5.0 Carbomentone 0.01 N-lauroylmethyltaurine sodium 1. 0 Sorbit 15.0 Xylitol 10.0 Silicic anhydride 20.0 Xanthan gum 2.0 Carrageenan 0.5 Saccharin sodium 0.1 Fragrance (excluding the second component) 1.0 Purified water Balance meter 100.0%

Example 17 Liquid Toothpaste-like Composition 17 Whitening Composition 17 (Liquid Toothpaste) Potassium Tripolyphosphate 1.0% Potassium Pyrophosphate 0.2 Sodium Hexametaphosphate (Cyclic) 0.3 Hinokitiol 02 Sodium lauryl phosphate 0.5 Propylene glycol 5.0 Sorbit 40.0 Silicic anhydride 10.0 Xanthan gum 1.0 Sodium fluoride 0.22 Sodium saccharin 0.1 Blue No. 0.0002 Fragrance (including the second component No) 1.0 Purified water Balance meter 100.0%

[0067]

According to the present invention, strong stains attached to the teeth are easily and reliably removed, and the effect of whitening the teeth is high.

[Brief description of the drawings]

FIG. 1 is a schematic diagram of a front lingual surface used in a stain removal test in an example of the present invention.

 ──────────────────────────────────────────────────続 き Continued on the front page (72) Inventor Masaki Yoshimura 1-3-7 Honjo, Sumida-ku, Tokyo Inside Lion Corporation (72) Inventor Makoto Watanabe 1-3-7, Honjo, Sumida-ku, Tokyo F-term in Lion Corporation (reference) 4C059 BB01 4C083 AA112 AB102 AB172 AB281 AB282 AB472 AC102 AC122 AC132 AC171 AC172 AC211 AC212 AC432 AC471 AC472 AC622 AC782 AC792 AC862 AD042 AD072 AD272 AD282 AD302 AD352 AD531 AD532 AD551 AD552 BB55 DD41 DD23 DD22 DD DD41 EE35 4C089 AA14 BA16 BC03 BE16 CA03

Claims (3)

[Claims] 1. A linear structure represented by the following general formula (1): M _{n + 2} P _n O _{3n + 1} (1) (where M represents Na or K and n ≧ 2) And a cyclic polyphosphate represented by the following general formula (2) (MPO ₃ ) _m (2) (where M represents Na or K and m ≧ 3). While containing one or more, citral, cinnamaldehyde, benzaldehyde, methyl salicylate, carvone, citral dimethyl acetal, citral diethyl acetal, citral propylene glycol acetal, heptyl aldehyde, octyl aldehyde, anisaldehyde, ethyl hexyl aldehyde, nonyl Aldehydes, diosphenol, ferrandral, carbomentone, thymoquinone, chrysantenone, klip T,
Tuyeon, Fencon, Piclocrocin, Santenone, α
-A tooth whitening composition comprising one or more compounds selected from the group consisting of ionone, β-ionone, α-iron, hinokitiol, α-shinepurine, γ-shinepurine and artemisia ketone. 2. A tooth whitening set comprising: the whitening composition according to claim 1; and an application tool for holding and fixing the composition to teeth. 3. An application tool for holding and fixing the composition to a tooth is formed into a water-insoluble tape, sheet, film, dental tray, mouth tray, mouthpiece, sponge, impression material, pack material, and dentition. The tooth whitening set according to claim 2, wherein the tooth whitening set is a chewing brush having a large number of protrusions on a tooth contact surface formed on a tooth cover or a tooth row.