JO2449B1 - Substituted Thiazole- benzoisothiazole Dioxide Derivatives, Process for their Preparation and their Use. - Google Patents
Substituted Thiazole- benzoisothiazole Dioxide Derivatives, Process for their Preparation and their Use.Info
- Publication number
- JO2449B1 JO2449B1 JO200481A JOP20040081A JO2449B1 JO 2449 B1 JO2449 B1 JO 2449B1 JO 200481 A JO200481 A JO 200481A JO P20040081 A JOP20040081 A JO P20040081A JO 2449 B1 JO2449 B1 JO 2449B1
- Authority
- JO
- Jordan
- Prior art keywords
- preparation
- substituted thiazole
- dioxide derivatives
- benzoisothiazole
- benzoisothiazole dioxide
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Abstract
The invention relates to compounds of the formula I In which the radicals have the stated meanings, and to the physiologically tolerated salts thereof. The compounds are suitable for example as medicaments for lowering the blood glucose and for the prevention and treatment of diabetes.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10334309A DE10334309A1 (en) | 2003-07-28 | 2003-07-28 | Substituted thiazole-Benzoisothiazoldioxidderivate, processes for their preparation and their use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JO2449B1 true JO2449B1 (en) | 2008-10-09 |
Family
ID=34111694
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JO200481A JO2449B1 (en) | 2003-07-28 | 2004-06-14 | Substituted Thiazole- benzoisothiazole Dioxide Derivatives, Process for their Preparation and their Use. |
Country Status (38)
| Country | Link |
|---|---|
| EP (1) | EP1651644B1 (en) |
| JP (1) | JP2007500145A (en) |
| KR (1) | KR20060052886A (en) |
| CN (1) | CN100413862C (en) |
| AR (1) | AR045113A1 (en) |
| AT (1) | ATE346065T1 (en) |
| AU (1) | AU2004261370B2 (en) |
| BR (1) | BRPI0412997A (en) |
| CA (1) | CA2533673A1 (en) |
| CR (1) | CR8202A (en) |
| CY (1) | CY1105962T1 (en) |
| DE (2) | DE10334309A1 (en) |
| DK (1) | DK1651644T3 (en) |
| EC (1) | ECSP066326A (en) |
| ES (1) | ES2276319T3 (en) |
| GT (1) | GT200400146A (en) |
| HK (1) | HK1091825A1 (en) |
| IL (1) | IL173289A0 (en) |
| JO (1) | JO2449B1 (en) |
| MA (1) | MA27932A1 (en) |
| MY (1) | MY141197A (en) |
| NO (1) | NO20060908L (en) |
| NZ (1) | NZ544975A (en) |
| OA (1) | OA13198A (en) |
| PA (1) | PA8607201A1 (en) |
| PE (1) | PE20050326A1 (en) |
| PL (1) | PL1651644T3 (en) |
| PT (1) | PT1651644E (en) |
| RS (1) | RS20060015A (en) |
| RU (1) | RU2350613C2 (en) |
| SA (1) | SA04250332B1 (en) |
| SI (1) | SI1651644T1 (en) |
| TN (1) | TNSN06030A1 (en) |
| TW (1) | TW200524923A (en) |
| UA (1) | UA83057C2 (en) |
| UY (1) | UY28443A1 (en) |
| WO (1) | WO2005012295A1 (en) |
| ZA (1) | ZA200510378B (en) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102004026532A1 (en) * | 2004-05-29 | 2006-01-05 | Sanofi-Aventis Deutschland Gmbh | Substituted Oxazole Benzoisothiazoldioxidderivate, process for their preparation and their use |
| AU2007245059B2 (en) | 2006-03-31 | 2011-07-28 | Novartis Ag | New compounds |
| MX2009001043A (en) | 2006-08-08 | 2009-02-06 | Sanofi Aventis | Arylaminoaryl-alkyl-substituted imidazolidine-2,4-diones, processes for preparing them, medicaments comprising these compounds, and their use. |
| EP2025674A1 (en) | 2007-08-15 | 2009-02-18 | sanofi-aventis | Substituted tetra hydro naphthalines, method for their manufacture and their use as drugs |
| UY31968A (en) | 2008-07-09 | 2010-01-29 | Sanofi Aventis | NEW HETEROCYCLIC DERIVATIVES, THEIR PROCESSES FOR THEIR PREPARATION, AND THEIR THERAPEUTIC USES |
| WO2010068601A1 (en) | 2008-12-08 | 2010-06-17 | Sanofi-Aventis | A crystalline heteroaromatic fluoroglycoside hydrate, processes for making, methods of use and pharmaceutical compositions thereof |
| CA2771278A1 (en) | 2009-08-26 | 2011-03-03 | Sanofi | Novel crystalline heteroaromatic fluoroglycoside hydrates, pharmaceuticals comprising these compounds and their use |
| WO2011107494A1 (en) | 2010-03-03 | 2011-09-09 | Sanofi | Novel aromatic glycoside derivatives, medicaments containing said compounds, and the use thereof |
| US8933024B2 (en) | 2010-06-18 | 2015-01-13 | Sanofi | Azolopyridin-3-one derivatives as inhibitors of lipases and phospholipases |
| US8530413B2 (en) | 2010-06-21 | 2013-09-10 | Sanofi | Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments |
| TW201215387A (en) | 2010-07-05 | 2012-04-16 | Sanofi Aventis | Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament |
| TW201221505A (en) | 2010-07-05 | 2012-06-01 | Sanofi Sa | Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament |
| TW201215388A (en) | 2010-07-05 | 2012-04-16 | Sanofi Sa | (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments |
| WO2012120057A1 (en) | 2011-03-08 | 2012-09-13 | Sanofi | Novel substituted phenyl-oxathiazine derivatives, method for producing them, drugs containing said compounds and the use thereof |
| WO2012120058A1 (en) | 2011-03-08 | 2012-09-13 | Sanofi | Oxathiazine derivatives which are substituted with benzyl or heteromethylene groups, method for producing them, their use as medicine and drug containing said derivatives and the use thereof |
| US8809324B2 (en) | 2011-03-08 | 2014-08-19 | Sanofi | Substituted phenyl-oxathiazine derivatives, method for producing them, drugs containing said compounds and the use thereof |
| WO2012120051A1 (en) | 2011-03-08 | 2012-09-13 | Sanofi | Benzyl-oxathiazine derivates substituted with adamantane or noradamantane, medicaments containing said compounds and use thereof |
| US8871758B2 (en) | 2011-03-08 | 2014-10-28 | Sanofi | Tetrasubstituted oxathiazine derivatives, method for producing them, their use as medicine and drug containing said derivatives and the use thereof |
| WO2012120054A1 (en) | 2011-03-08 | 2012-09-13 | Sanofi | Di- and tri-substituted oxathiazine derivates, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof |
| US8828995B2 (en) | 2011-03-08 | 2014-09-09 | Sanofi | Branched oxathiazine derivatives, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof |
| WO2012120055A1 (en) | 2011-03-08 | 2012-09-13 | Sanofi | Di- and tri-substituted oxathiazine derivates, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof |
| EP2766349B1 (en) | 2011-03-08 | 2016-06-01 | Sanofi | Oxathiazine derivatives substituted with carbocycles or heterocycles, method for producing same, drugs containing said compounds, and use thereof |
| EP2567959B1 (en) | 2011-09-12 | 2014-04-16 | Sanofi | 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors |
| WO2013037390A1 (en) | 2011-09-12 | 2013-03-21 | Sanofi | 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors |
| WO2013045413A1 (en) | 2011-09-27 | 2013-04-04 | Sanofi | 6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors |
| WO2025017207A1 (en) * | 2023-07-20 | 2025-01-23 | Cemm - Forschungszentrum Für Molekulare Medizin Gmbh | Inhibitors of smndc1 and their therapeutic use |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3539584A (en) * | 1967-11-14 | 1970-11-10 | Colgate Palmolive Co | 5-substituted-2,1-benzisothiazolines |
| JPH04128276A (en) * | 1990-09-19 | 1992-04-28 | Pfizer Pharmaceut Co Ltd | Aminobenzosultam derivatives and their uses |
| CO5190696A1 (en) * | 1999-06-16 | 2002-08-29 | Smithkline Beecham Corp | ANTAGONISTS OF IL-8 RECEIVERS |
| DE10038709A1 (en) * | 2000-08-09 | 2002-02-28 | Aventis Pharma Gmbh | Substituted and unsubstituted benzooxathiazoles and compounds derived from them |
-
2003
- 2003-07-28 DE DE10334309A patent/DE10334309A1/en not_active Withdrawn
-
2004
- 2004-06-14 JO JO200481A patent/JO2449B1/en active
- 2004-07-13 PE PE2004000664A patent/PE20050326A1/en not_active Application Discontinuation
- 2004-07-15 DE DE502004002117T patent/DE502004002117D1/en not_active Expired - Lifetime
- 2004-07-15 RS YUP-2006/0015A patent/RS20060015A/en unknown
- 2004-07-15 AT AT04741034T patent/ATE346065T1/en not_active IP Right Cessation
- 2004-07-15 RU RU2006106231/04A patent/RU2350613C2/en not_active IP Right Cessation
- 2004-07-15 WO PCT/EP2004/007847 patent/WO2005012295A1/en active IP Right Grant
- 2004-07-15 JP JP2006521446A patent/JP2007500145A/en not_active Abandoned
- 2004-07-15 NZ NZ544975A patent/NZ544975A/en unknown
- 2004-07-15 AU AU2004261370A patent/AU2004261370B2/en not_active Ceased
- 2004-07-15 UA UAA200602134A patent/UA83057C2/en unknown
- 2004-07-15 CN CNB2004800220877A patent/CN100413862C/en not_active Expired - Fee Related
- 2004-07-15 ES ES04741034T patent/ES2276319T3/en not_active Expired - Lifetime
- 2004-07-15 EP EP04741034A patent/EP1651644B1/en not_active Expired - Lifetime
- 2004-07-15 BR BRPI0412997-0A patent/BRPI0412997A/en not_active IP Right Cessation
- 2004-07-15 DK DK04741034T patent/DK1651644T3/en active
- 2004-07-15 CA CA002533673A patent/CA2533673A1/en not_active Abandoned
- 2004-07-15 SI SI200430126T patent/SI1651644T1/en unknown
- 2004-07-15 OA OA1200600026A patent/OA13198A/en unknown
- 2004-07-15 PL PL04741034T patent/PL1651644T3/en unknown
- 2004-07-15 PA PA20048607201A patent/PA8607201A1/en unknown
- 2004-07-15 PT PT04741034T patent/PT1651644E/en unknown
- 2004-07-15 KR KR1020067001721A patent/KR20060052886A/en not_active Application Discontinuation
- 2004-07-23 GT GT200400146A patent/GT200400146A/en unknown
- 2004-07-26 AR ARP040102644A patent/AR045113A1/en not_active Application Discontinuation
- 2004-07-26 TW TW093122232A patent/TW200524923A/en unknown
- 2004-07-27 MY MYPI20043005A patent/MY141197A/en unknown
- 2004-07-28 UY UY28443A patent/UY28443A1/en unknown
- 2004-10-11 SA SA04250332A patent/SA04250332B1/en unknown
-
2005
- 2005-12-21 ZA ZA200510378A patent/ZA200510378B/en unknown
-
2006
- 2006-01-18 CR CR8202A patent/CR8202A/en not_active Application Discontinuation
- 2006-01-22 IL IL173289A patent/IL173289A0/en unknown
- 2006-01-26 EC EC2006006326A patent/ECSP066326A/en unknown
- 2006-01-26 MA MA28753A patent/MA27932A1/en unknown
- 2006-01-27 TN TNP2006000030A patent/TNSN06030A1/en unknown
- 2006-02-24 NO NO20060908A patent/NO20060908L/en not_active Application Discontinuation
- 2006-11-10 HK HK06112382A patent/HK1091825A1/en not_active IP Right Cessation
-
2007
- 2007-01-29 CY CY20071100112T patent/CY1105962T1/en unknown
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