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ITMI20032259A1 - Nuovo polimorfo dell'acido 1-ciclopropil-7-(s,s-2,8-diazabciclo-4.3.0-non-8-il)-6-fluoro-1,4-diidro-8-metossi-4-oxo-chinolin carbossilico cloridrato e metodi per la sua preparazione - Google Patents

Nuovo polimorfo dell'acido 1-ciclopropil-7-(s,s-2,8-diazabciclo-4.3.0-non-8-il)-6-fluoro-1,4-diidro-8-metossi-4-oxo-chinolin carbossilico cloridrato e metodi per la sua preparazione

Info

Publication number
ITMI20032259A1
ITMI20032259A1 IT002259A ITMI20032259A ITMI20032259A1 IT MI20032259 A1 ITMI20032259 A1 IT MI20032259A1 IT 002259 A IT002259 A IT 002259A IT MI20032259 A ITMI20032259 A IT MI20032259A IT MI20032259 A1 ITMI20032259 A1 IT MI20032259A1
Authority
IT
Italy
Prior art keywords
metossi
carbosxyl
diidro
diazabiclo
chloridrate
Prior art date
Application number
IT002259A
Other languages
English (en)
Inventor
Valentina Aromatario
Pietro Massario
Stefano Turchetta
Original Assignee
Chemi Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chemi Spa filed Critical Chemi Spa
Priority to IT002259A priority Critical patent/ITMI20032259A1/it
Priority to PCT/EP2004/052699 priority patent/WO2005054240A1/en
Priority to ES04791330T priority patent/ES2319125T3/es
Priority to EP04791330A priority patent/EP1685130B1/en
Priority to US10/580,173 priority patent/US8236817B2/en
Priority to JP2006540424A priority patent/JP4732361B2/ja
Priority to DE602004018370T priority patent/DE602004018370D1/de
Publication of ITMI20032259A1 publication Critical patent/ITMI20032259A1/it
Priority to US13/538,249 priority patent/US20120277263A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IT002259A 2003-11-20 2003-11-20 Nuovo polimorfo dell'acido 1-ciclopropil-7-(s,s-2,8-diazabciclo-4.3.0-non-8-il)-6-fluoro-1,4-diidro-8-metossi-4-oxo-chinolin carbossilico cloridrato e metodi per la sua preparazione ITMI20032259A1 (it)

Priority Applications (8)

Application Number Priority Date Filing Date Title
IT002259A ITMI20032259A1 (it) 2003-11-20 2003-11-20 Nuovo polimorfo dell'acido 1-ciclopropil-7-(s,s-2,8-diazabciclo-4.3.0-non-8-il)-6-fluoro-1,4-diidro-8-metossi-4-oxo-chinolin carbossilico cloridrato e metodi per la sua preparazione
PCT/EP2004/052699 WO2005054240A1 (en) 2003-11-20 2004-10-28 Polymorphs of 1-cyclopropyl-7-([s,s]-2,8-diazadicyclo[4.3.0]non-8-yl)-6-fluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinoline carboxylic acid hydrochloride and methods for the preparation thereof
ES04791330T ES2319125T3 (es) 2003-11-20 2004-10-28 Polimorfos del clorhidrato del acido 1-ciclopropil-7-((s,s)-2,8-diazadiciclo(4.3.0)-non-8-il)-6-fluoro-1,4-dihidro-8-metoxi-4-oxo-3-quinolina carboxilico y metodos para la preparacion de los mismos.
EP04791330A EP1685130B1 (en) 2003-11-20 2004-10-28 Polymorphs of 1-cyclopropyl-7-([s,s] - 2,8-diazadicyclo [4.3.0] non-8-yl) -6-fluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinoline carboxylic acid hydrochloride and methods for the preparation thereof
US10/580,173 US8236817B2 (en) 2003-11-20 2004-10-28 Polymorphs of 1-cyclopropy1-7-([s,s])-2,8-diazadicyclo[4.3.0]non-8-yl)-6-fluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinoline carboxylic acid hydrochloride and methods for the preparation thereof
JP2006540424A JP4732361B2 (ja) 2003-11-20 2004-10-28 塩酸１−シクロプロピル−７−（（ｓ，ｓ）−２，８−ジアザジシクロ（４．３．０）ノン−８−イル）−６−フルオロ−１，４−ジヒドロ−８−メトキシ−４−オキソ−３−キノリンカルボン酸の多形およびその調製方法
DE602004018370T DE602004018370D1 (de) 2003-11-20 2004-10-28 Polymorphe von 1-cyclopropyl-7-(äs,sü - 2,8-diazadicyclo ä4.3.0ü non-8-yl) -6-fluor-1,4-dihydro-8-methoxy-4-oxo-3-chinolincarbonsäurehydrochlorid und verfahren zu deren herstellung
US13/538,249 US20120277263A1 (en) 2003-11-20 2012-06-29 Polymorphs of 1-cyclopropyl-7-([s,s])-2,8-diazadicyclo[4.3.0]non-8-yl)-6-fluoro-1,4-dihydro -8-methoxy-4-oxo-3-quinoline carboxylic acid hydrochloride and methods for the preparation thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT002259A ITMI20032259A1 (it) 2003-11-20 2003-11-20 Nuovo polimorfo dell'acido 1-ciclopropil-7-(s,s-2,8-diazabciclo-4.3.0-non-8-il)-6-fluoro-1,4-diidro-8-metossi-4-oxo-chinolin carbossilico cloridrato e metodi per la sua preparazione

Publications (1)

Publication Number Publication Date
ITMI20032259A1 true ITMI20032259A1 (it) 2005-05-21

Family

ID=43721882

Family Applications (1)

Application Number Title Priority Date Filing Date
IT002259A ITMI20032259A1 (it) 2003-11-20 2003-11-20 Nuovo polimorfo dell'acido 1-ciclopropil-7-(s,s-2,8-diazabciclo-4.3.0-non-8-il)-6-fluoro-1,4-diidro-8-metossi-4-oxo-chinolin carbossilico cloridrato e metodi per la sua preparazione

Country Status (3)

Country Link
US (2) US8236817B2 (it)
JP (1) JP4732361B2 (it)
IT (1) ITMI20032259A1 (it)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005012285A1 (en) * 2003-08-05 2005-02-10 Matrix Laboratories Ltd An improved process for the preparation of moxifloxacin hydrochloride

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3906365A1 (de) * 1988-07-15 1990-01-18 Bayer Ag 7-(1-pyrrolidinyl)-3-chinolon- und -naphthyridoncarbonsaeure-derivate, verfahren sowie substituierte (oxa)diazabicyclooctane und -nonane als zwischenprodukte zu ihrer herstellung, und sie enthaltende antibakterielle mittel und futterzusatzstoffe
TW209865B (it) 1992-01-10 1993-07-21 Bayer Ag
ZA946853B (en) 1993-09-10 1995-04-24 Daiichi Seiyaku Co Crystals of antimicrobial compound.
DE19546249A1 (de) * 1995-12-12 1997-06-19 Bayer Ag Neue Kristallmodifikation des 1-Cyclopropyl-7-([S,S]-2,8-diazabicyclo[4,3,0]non-8-yl)-6-fluor-1,4-dihydro-8-methoxy-4-oxo-3-chinolincarbonsäure Hydrochlorid (CDCH), Verfahren zu dessen Herstellung und diese enthaltende pharmazeutische Zubereitungen
DE19751948A1 (de) * 1997-11-24 1999-05-27 Bayer Ag Verfahren zur Herstellung von 8-Methoxy-Chinoloncarbonsäuren
EP1262477B1 (en) * 2000-02-09 2008-09-03 Daiichi Sankyo Company, Limited Anti-acid-fast bacterial agents containing pyridonecarboxylic acids as the active ingredient
US6627646B2 (en) * 2001-07-17 2003-09-30 Sepracor Inc. Norastemizole polymorphs
HUP0402535A2 (hu) 2001-12-10 2005-04-28 Bristol-Myers Squibb Co. RSV fúzió inhibitor hatású imidazo-piridin-vegyület dihidroklorid-monohidrát sója és az ezt tartalmazó gyógyszerkészítmények
ATE439840T1 (de) 2003-04-09 2009-09-15 Reddys Lab Ltd Dr Kristalline form iii von wasserfreiem moxifloxacin-hydrochlorid und ein verfahren zu seiner herstellung
WO2005012285A1 (en) * 2003-08-05 2005-02-10 Matrix Laboratories Ltd An improved process for the preparation of moxifloxacin hydrochloride

Also Published As

Publication number Publication date
JP2007511580A (ja) 2007-05-10
JP4732361B2 (ja) 2011-07-27
US20120277263A1 (en) 2012-11-01
US8236817B2 (en) 2012-08-07
US20070072895A1 (en) 2007-03-29

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