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ITMI20040795A1 - Composizione farmaceutica solida secca suo processo di preparazione e sospensione acquosa stabile ottenuta dalla stessa - Google Patents

Composizione farmaceutica solida secca suo processo di preparazione e sospensione acquosa stabile ottenuta dalla stessa

Info

Publication number
ITMI20040795A1
ITMI20040795A1 IT000795A ITMI20040795A ITMI20040795A1 IT MI20040795 A1 ITMI20040795 A1 IT MI20040795A1 IT 000795 A IT000795 A IT 000795A IT MI20040795 A ITMI20040795 A IT MI20040795A IT MI20040795 A1 ITMI20040795 A1 IT MI20040795A1
Authority
IT
Italy
Prior art keywords
itself
pharmaceutical composition
solid pharmaceutical
dry solid
water preparation
Prior art date
Application number
IT000795A
Other languages
English (en)
Inventor
Mariella Artusi
Giovanni Caponetti
Mora Paolo Corvi
Loretta Maggi
Original Assignee
Eratech S R L
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eratech S R L filed Critical Eratech S R L
Priority to IT000795A priority Critical patent/ITMI20040795A1/it
Publication of ITMI20040795A1 publication Critical patent/ITMI20040795A1/it
Priority to US11/578,661 priority patent/US8252334B2/en
Priority to JP2007508845A priority patent/JP5285904B2/ja
Priority to PCT/EP2005/004277 priority patent/WO2005102283A1/en
Priority to ES05733765T priority patent/ES2939532T3/es
Priority to PT57337651T priority patent/PT1755558T/pt
Priority to EP05733765.1A priority patent/EP1755558B1/en
Priority to US13/558,566 priority patent/US20130052233A1/en
Priority to US14/631,999 priority patent/US20150202156A1/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/143Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with inorganic compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Dispersion Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IT000795A 2004-04-23 2004-04-23 Composizione farmaceutica solida secca suo processo di preparazione e sospensione acquosa stabile ottenuta dalla stessa ITMI20040795A1 (it)

Priority Applications (9)

Application Number Priority Date Filing Date Title
IT000795A ITMI20040795A1 (it) 2004-04-23 2004-04-23 Composizione farmaceutica solida secca suo processo di preparazione e sospensione acquosa stabile ottenuta dalla stessa
US11/578,661 US8252334B2 (en) 2004-04-23 2005-04-21 Dry powder pharmaceutical compositions comprising surfactants, hydrophobic active principles, and water-soluble excipients, process of preparing, and stable aqueous suspensions thereof
JP2007508845A JP5285904B2 (ja) 2004-04-23 2005-04-21 乾燥粉末医薬組成物、その製造方法、およびその組成物から得られる安定な水性懸濁液
PCT/EP2005/004277 WO2005102283A1 (en) 2004-04-23 2005-04-21 Dry powder pharmaceutical composition, its preparation process and stable aqueous suspension obtained from such composition
ES05733765T ES2939532T3 (es) 2004-04-23 2005-04-21 Composición farmacéutica en polvo seco, su proceso de preparación y suspensión acuosa estable obtenida a partir de dicha composición
PT57337651T PT1755558T (pt) 2004-04-23 2005-04-21 Composição farmacêutica de pó seco, o seu processo de preparação e suspensão aquosa estável obtida a partir de tal composição
EP05733765.1A EP1755558B1 (en) 2004-04-23 2005-04-21 Dry powder pharmaceutical composition, its preparation process and stable aqueous suspension obtained from such composition
US13/558,566 US20130052233A1 (en) 2004-04-23 2012-07-26 Dry Powder Pharmaceutical Compositions, Its Preparation Process and Stable Aqueous Suspension Obtained from such Composition
US14/631,999 US20150202156A1 (en) 2004-04-23 2015-02-26 Dry powder pharmaceutical composition, its preparation process and stable aqueous suspension obtained from such composition

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT000795A ITMI20040795A1 (it) 2004-04-23 2004-04-23 Composizione farmaceutica solida secca suo processo di preparazione e sospensione acquosa stabile ottenuta dalla stessa

Publications (1)

Publication Number Publication Date
ITMI20040795A1 true ITMI20040795A1 (it) 2004-07-23

Family

ID=34956435

Family Applications (1)

Application Number Title Priority Date Filing Date
IT000795A ITMI20040795A1 (it) 2004-04-23 2004-04-23 Composizione farmaceutica solida secca suo processo di preparazione e sospensione acquosa stabile ottenuta dalla stessa

Country Status (7)

Country Link
US (3) US8252334B2 (it)
EP (1) EP1755558B1 (it)
JP (1) JP5285904B2 (it)
ES (1) ES2939532T3 (it)
IT (1) ITMI20040795A1 (it)
PT (1) PT1755558T (it)
WO (1) WO2005102283A1 (it)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITMI20051999A1 (it) 2005-10-21 2007-04-22 Eratech S R L Formulazioni inalatorie di farmaci in fora di polvere secca per somministrazione come tale o con nebulizzatore e dotate di elevata erogabilita' respirabilita' e stabilita'
JP5113328B2 (ja) * 2005-11-07 2013-01-09 田辺三菱製薬株式会社 エマルション並びにそれを用いた目的物質粒子の製造方法及び医薬品
WO2008062475A2 (en) * 2006-10-26 2008-05-29 Cadila Healthcare Limited Pharmaceutical compositions of ursodiol
US20120149720A1 (en) * 2010-07-30 2012-06-14 Ranbaxy Laboratories Limited Valacyclovir formulations
US10183182B2 (en) 2010-08-02 2019-01-22 Guided Therapy Systems, Llc Methods and systems for treating plantar fascia
US9408797B2 (en) 2011-06-03 2016-08-09 Allergan, Inc. Dermal filler compositions for fine line treatment
WO2019126766A1 (en) * 2017-12-21 2019-06-27 Taiwan Liposome Co., Ltd. Sustained-release triptan compositions and method of use the same through subdermal route or the like

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2269992A (en) * 1992-08-14 1994-03-02 Rh Ne Poulenc Rorer Limited Powder inhalation formulations
US6001336A (en) * 1996-12-31 1999-12-14 Inhale Therapeutic Systems Processes for spray drying aqueous suspensions of hydrophobic drugs and compositions thereof
ATE287257T1 (de) 1997-01-16 2005-02-15 Massachusetts Inst Technology Zubereitung von partikelhaltigen arzneimitteln zur inhalation
US6946117B1 (en) * 1997-09-29 2005-09-20 Nektar Therapeutics Stabilized preparations for use in nebulizers
ES2195408T5 (es) 1997-09-29 2010-11-25 Novartis Ag Procedimiento de formación de polvo que comprende micropartículas perforadas.
US6187765B1 (en) 1997-10-09 2001-02-13 Schering Corporation Mometasone furoate suspensions for nebulization
SE9704186D0 (sv) * 1997-11-14 1997-11-14 Astra Ab New composition of matter
IT1303692B1 (it) * 1998-11-03 2001-02-23 Chiesi Farma Spa Procedimento per la preparazione di sospensioni di particelle difarmaci da somministrare per inalazione.
ITMI991582A1 (it) * 1999-07-16 2001-01-16 Chiesi Farma Spa Polveri costituite da particelle aventi la superficie perfettamente levigata da utilizzare come veicoli per la preparazione di miscele inala
GB0009469D0 (en) * 2000-04-17 2000-06-07 Vectura Ltd Improvements in or relating to formalities for use in inhaler devices
GB0107106D0 (en) * 2001-03-21 2001-05-09 Boehringer Ingelheim Pharma Powder inhaler formulations
US20040045546A1 (en) * 2002-09-05 2004-03-11 Peirce Management, Llc Pharmaceutical delivery system for oral inhalation through nebulization consisting of inert substrate impregnated with substance (S) to be solubilized or suspended prior to use

Also Published As

Publication number Publication date
PT1755558T (pt) 2023-03-02
US20150202156A1 (en) 2015-07-23
EP1755558A1 (en) 2007-02-28
WO2005102283A1 (en) 2005-11-03
EP1755558B1 (en) 2022-12-21
JP5285904B2 (ja) 2013-09-11
US20070224276A1 (en) 2007-09-27
US8252334B2 (en) 2012-08-28
JP2007533694A (ja) 2007-11-22
ES2939532T3 (es) 2023-04-24
US20130052233A1 (en) 2013-02-28

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