IT7924316A0 - Procedimento di purificazione dell'acido ursodesossicolico attraverso nuovi derivati. - Google Patents
Procedimento di purificazione dell'acido ursodesossicolico attraverso nuovi derivati.Info
- Publication number
- IT7924316A0 IT7924316A0 IT7924316A IT2431679A IT7924316A0 IT 7924316 A0 IT7924316 A0 IT 7924316A0 IT 7924316 A IT7924316 A IT 7924316A IT 2431679 A IT2431679 A IT 2431679A IT 7924316 A0 IT7924316 A0 IT 7924316A0
- Authority
- IT
- Italy
- Prior art keywords
- purification
- ursodeoxycholic acid
- new derivatives
- derivatives
- new
- Prior art date
Links
- RUDATBOHQWOJDD-UHFFFAOYSA-N (3beta,5beta,7alpha)-3,7-Dihydroxycholan-24-oic acid Natural products OC1CC2CC(O)CCC2(C)C2C1C1CCC(C(CCC(O)=O)C)C1(C)CC2 RUDATBOHQWOJDD-UHFFFAOYSA-N 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 238000000746 purification Methods 0.000 title 1
- RUDATBOHQWOJDD-UZVSRGJWSA-N ursodeoxycholic acid Chemical compound C([C@H]1C[C@@H]2O)[C@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@@H](CCC(O)=O)C)[C@@]2(C)CC1 RUDATBOHQWOJDD-UZVSRGJWSA-N 0.000 title 1
- 229960001661 ursodiol Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
- C07J9/005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane containing a carboxylic function directly attached or attached by a chain containing only carbon atoms to the cyclopenta[a]hydrophenanthrene skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT24316/79A IT1165252B (it) | 1979-07-12 | 1979-07-12 | Procedimento di purificazione dell'acido ursodesossicolico attraverso nuovi derivati |
EP80103817A EP0024292B1 (en) | 1979-07-12 | 1980-07-04 | Process for the separation of ursodeoxycholic acid from chenodeoxycholic acid and products obtained during the process |
DE8080103817T DE3063603D1 (en) | 1979-07-12 | 1980-07-04 | Process for the separation of ursodeoxycholic acid from chenodeoxycholic acid and products obtained during the process |
AT80103817T ATE3641T1 (de) | 1979-07-12 | 1980-07-04 | Verfahren zum trennen von ursodesoxycholsaeure und chenodesoxycholsaeure und waehrend des verfahrens erhaltene produkte. |
JP9338680A JPS5632500A (en) | 1979-07-12 | 1980-07-10 | Purification of ursodeoxycholic acid and novel silyl derivative of ursodeoxycholic acid therefor |
US06/167,468 US4316848A (en) | 1979-07-12 | 1980-07-11 | Process for the purification of ursodeoxycholic acid |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT24316/79A IT1165252B (it) | 1979-07-12 | 1979-07-12 | Procedimento di purificazione dell'acido ursodesossicolico attraverso nuovi derivati |
Publications (2)
Publication Number | Publication Date |
---|---|
IT7924316A0 true IT7924316A0 (it) | 1979-07-12 |
IT1165252B IT1165252B (it) | 1987-04-22 |
Family
ID=11213071
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT24316/79A IT1165252B (it) | 1979-07-12 | 1979-07-12 | Procedimento di purificazione dell'acido ursodesossicolico attraverso nuovi derivati |
Country Status (6)
Country | Link |
---|---|
US (1) | US4316848A (it) |
EP (1) | EP0024292B1 (it) |
JP (1) | JPS5632500A (it) |
AT (1) | ATE3641T1 (it) |
DE (1) | DE3063603D1 (it) |
IT (1) | IT1165252B (it) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1132055B (it) * | 1980-05-14 | 1986-06-25 | Erregierre Spa | Processo per la preparazione di acido ursodesossicolico ad alta purezza |
IT1137459B (it) * | 1981-04-14 | 1986-09-10 | Erregierre Spa | Prodesso per la preparazione di acido ursodeossicolico ad alta purezza |
IT1167478B (it) * | 1981-07-24 | 1987-05-13 | Carlo Scolastico | Derivati dell'acido ursodesossicolico |
IT1167479B (it) * | 1981-07-24 | 1987-05-13 | Carlo Scolastico | Derivati dell'acido chenodesossicolico |
JPS59159467A (ja) * | 1983-03-02 | 1984-09-10 | Toshiba Mach Co Ltd | 非接触形メカニカルシ−ル |
AU2002308295B2 (en) | 2001-03-12 | 2007-08-23 | Intercept Pharmaceuticals, Inc. | Steroids as agonists for FXR |
KR100439069B1 (ko) * | 2002-04-03 | 2004-07-05 | 노일근 | 초미립 침상결정형 우루소데옥시콜린산 및 그 제조방법 |
CN102766185B (zh) * | 2012-08-02 | 2015-04-22 | 苏州天绿生物制药有限公司 | 一种从熊去氧胆酸废母液中分别回收熊去氧胆酸和鹅去氧胆酸的方法 |
CN104017043A (zh) * | 2014-06-20 | 2014-09-03 | 华东理工大学 | 硅烷化技术纯化熊去氧胆酸的方法 |
CN105503987B (zh) * | 2015-12-28 | 2017-05-31 | 成都市新功生物科技有限公司 | 一种载铜活性炭催化氧化还原法用鹅去氧胆酸合成熊去氧胆酸的方法 |
CN106520888B (zh) * | 2016-10-28 | 2020-01-07 | 西安岳达生物科技股份有限公司 | 基于化学氧化和酶催化结合技术制备熊去氧胆酸的方法 |
IT202100019631A1 (it) * | 2021-07-23 | 2023-01-23 | Newchem S P A | Metodo per produrre estetrolo e i suoi intermedi |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3671555A (en) * | 1969-03-05 | 1972-06-20 | Jenapharm Veb | Trialkylsyliloxy-steroid compounds and process for making same |
US3919266A (en) * | 1972-09-21 | 1975-11-11 | Intellectual Property Dev Corp | Production of bile acids |
US3833620A (en) * | 1972-11-16 | 1974-09-03 | Intellectual Property Dev Corp | Production of chenodeoxycholic acid |
-
1979
- 1979-07-12 IT IT24316/79A patent/IT1165252B/it active
-
1980
- 1980-07-04 AT AT80103817T patent/ATE3641T1/de not_active IP Right Cessation
- 1980-07-04 EP EP80103817A patent/EP0024292B1/en not_active Expired
- 1980-07-04 DE DE8080103817T patent/DE3063603D1/de not_active Expired
- 1980-07-10 JP JP9338680A patent/JPS5632500A/ja active Granted
- 1980-07-11 US US06/167,468 patent/US4316848A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP0024292B1 (en) | 1983-06-01 |
ATE3641T1 (de) | 1983-06-15 |
US4316848A (en) | 1982-02-23 |
JPS617437B2 (it) | 1986-03-06 |
JPS5632500A (en) | 1981-04-01 |
EP0024292A1 (en) | 1981-03-04 |
IT1165252B (it) | 1987-04-22 |
DE3063603D1 (en) | 1983-07-07 |
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