IT1398480B1 - Sistema microfluidico - Google Patents
Sistema microfluidicoInfo
- Publication number
- IT1398480B1 IT1398480B1 ITBO2009A000806A ITBO20090806A IT1398480B1 IT 1398480 B1 IT1398480 B1 IT 1398480B1 IT BO2009A000806 A ITBO2009A000806 A IT BO2009A000806A IT BO20090806 A ITBO20090806 A IT BO20090806A IT 1398480 B1 IT1398480 B1 IT 1398480B1
- Authority
- IT
- Italy
- Prior art keywords
- microfluid system
- microfluid
- Prior art date
Links
Classifications
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
- F16K99/00—Subject matter not provided for in other groups of this subclass
- F16K99/0001—Microvalves
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
- F16K99/00—Subject matter not provided for in other groups of this subclass
- F16K99/0001—Microvalves
- F16K99/0003—Constructional types of microvalves; Details of the cutting-off member
- F16K99/0015—Diaphragm or membrane valves
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
- F16K99/00—Subject matter not provided for in other groups of this subclass
- F16K99/0001—Microvalves
- F16K99/0034—Operating means specially adapted for microvalves
- F16K99/0055—Operating means specially adapted for microvalves actuated by fluids
- F16K99/0059—Operating means specially adapted for microvalves actuated by fluids actuated by a pilot fluid
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0887—Laminated structure
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/14—Means for pressure control
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
- B01L2400/0481—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure squeezing of channels or chambers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
- B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/06—Valves, specific forms thereof
- B01L2400/0633—Valves, specific forms thereof with moving parts
- B01L2400/0638—Valves, specific forms thereof with moving parts membrane valves, flap valves
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/02—Burettes; Pipettes
- B01L3/0241—Drop counters; Drop formers
- B01L3/0265—Drop counters; Drop formers using valves to interrupt or meter fluid flow, e.g. using solenoids or metering valves
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/50273—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means or forces applied to move the fluids
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502738—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by integrated valves
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29L—INDEXING SCHEME ASSOCIATED WITH SUBCLASS B29C, RELATING TO PARTICULAR ARTICLES
- B29L2031/00—Other particular articles
- B29L2031/748—Machines or parts thereof not otherwise provided for
- B29L2031/7506—Valves
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F15—FLUID-PRESSURE ACTUATORS; HYDRAULICS OR PNEUMATICS IN GENERAL
- F15C—FLUID-CIRCUIT ELEMENTS PREDOMINANTLY USED FOR COMPUTING OR CONTROL PURPOSES
- F15C3/00—Circuit elements having moving parts
- F15C3/04—Circuit elements having moving parts using diaphragms
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
- F16K99/00—Subject matter not provided for in other groups of this subclass
- F16K2099/0073—Fabrication methods specifically adapted for microvalves
- F16K2099/0074—Fabrication methods specifically adapted for microvalves using photolithography, e.g. etching
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
- F16K99/00—Subject matter not provided for in other groups of this subclass
- F16K2099/0073—Fabrication methods specifically adapted for microvalves
- F16K2099/0078—Fabrication methods specifically adapted for microvalves using moulding or stamping
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
- F16K99/00—Subject matter not provided for in other groups of this subclass
- F16K2099/0082—Microvalves adapted for a particular use
- F16K2099/0084—Chemistry or biology, e.g. "lab-on-a-chip" technology
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
- F16K7/00—Diaphragm valves or cut-off apparatus, e.g. with a member deformed, but not moved bodily, to close the passage ; Pinch valves
- F16K7/12—Diaphragm valves or cut-off apparatus, e.g. with a member deformed, but not moved bodily, to close the passage ; Pinch valves with flat, dished, or bowl-shaped diaphragm
- F16K7/123—Diaphragm valves or cut-off apparatus, e.g. with a member deformed, but not moved bodily, to close the passage ; Pinch valves with flat, dished, or bowl-shaped diaphragm the seat being formed on the bottom of the fluid line
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
- F16K7/00—Diaphragm valves or cut-off apparatus, e.g. with a member deformed, but not moved bodily, to close the passage ; Pinch valves
- F16K7/12—Diaphragm valves or cut-off apparatus, e.g. with a member deformed, but not moved bodily, to close the passage ; Pinch valves with flat, dished, or bowl-shaped diaphragm
- F16K7/126—Diaphragm valves or cut-off apparatus, e.g. with a member deformed, but not moved bodily, to close the passage ; Pinch valves with flat, dished, or bowl-shaped diaphragm the seat being formed on a rib perpendicular to the fluid line
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
- F16K7/00—Diaphragm valves or cut-off apparatus, e.g. with a member deformed, but not moved bodily, to close the passage ; Pinch valves
- F16K7/12—Diaphragm valves or cut-off apparatus, e.g. with a member deformed, but not moved bodily, to close the passage ; Pinch valves with flat, dished, or bowl-shaped diaphragm
- F16K7/14—Diaphragm valves or cut-off apparatus, e.g. with a member deformed, but not moved bodily, to close the passage ; Pinch valves with flat, dished, or bowl-shaped diaphragm arranged to be deformed against a flat seat
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
- F16K7/00—Diaphragm valves or cut-off apparatus, e.g. with a member deformed, but not moved bodily, to close the passage ; Pinch valves
- F16K7/12—Diaphragm valves or cut-off apparatus, e.g. with a member deformed, but not moved bodily, to close the passage ; Pinch valves with flat, dished, or bowl-shaped diaphragm
- F16K7/14—Diaphragm valves or cut-off apparatus, e.g. with a member deformed, but not moved bodily, to close the passage ; Pinch valves with flat, dished, or bowl-shaped diaphragm arranged to be deformed against a flat seat
- F16K7/17—Diaphragm valves or cut-off apparatus, e.g. with a member deformed, but not moved bodily, to close the passage ; Pinch valves with flat, dished, or bowl-shaped diaphragm arranged to be deformed against a flat seat the diaphragm being actuated by fluid pressure
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
- F16K99/00—Subject matter not provided for in other groups of this subclass
- F16K99/0001—Microvalves
- F16K99/0034—Operating means specially adapted for microvalves
Landscapes
- Engineering & Computer Science (AREA)
- General Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Dispersion Chemistry (AREA)
- Mechanical Engineering (AREA)
- Micromachines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITBO2009A000806A IT1398480B1 (it) | 2009-12-17 | 2009-12-17 | Sistema microfluidico |
EP10810876.2A EP2513533B1 (en) | 2009-12-17 | 2010-12-16 | Micro-fluidic system |
DK10810876.2T DK2513533T3 (en) | 2009-12-17 | 2010-12-16 | microfluidic |
PCT/IB2010/003277 WO2011073782A1 (en) | 2009-12-17 | 2010-12-16 | Micro-fluidic system |
US13/515,959 US9127783B2 (en) | 2009-12-17 | 2010-12-16 | Micro-fluidic system |
ES10810876.2T ES2557291T3 (es) | 2009-12-17 | 2010-12-16 | Sistema de microfluidos |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITBO2009A000806A IT1398480B1 (it) | 2009-12-17 | 2009-12-17 | Sistema microfluidico |
Publications (2)
Publication Number | Publication Date |
---|---|
ITBO20090806A1 ITBO20090806A1 (it) | 2011-06-18 |
IT1398480B1 true IT1398480B1 (it) | 2013-03-01 |
Family
ID=42472761
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ITBO2009A000806A IT1398480B1 (it) | 2009-12-17 | 2009-12-17 | Sistema microfluidico |
Country Status (6)
Country | Link |
---|---|
US (1) | US9127783B2 (it) |
EP (1) | EP2513533B1 (it) |
DK (1) | DK2513533T3 (it) |
ES (1) | ES2557291T3 (it) |
IT (1) | IT1398480B1 (it) |
WO (1) | WO2011073782A1 (it) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1397820B1 (it) * | 2009-12-17 | 2013-02-04 | Silicon Biosystems Spa | Sistema microfluidico |
IT1403518B1 (it) | 2010-12-22 | 2013-10-31 | Silicon Biosystems Spa | Dispositivo microfluidico per la manipolazione di particelle |
JP5740011B2 (ja) | 2012-01-31 | 2015-06-24 | ジヤトコ株式会社 | 自動変速機のコントロールバルブボディ構造 |
WO2014190258A1 (en) * | 2013-05-23 | 2014-11-27 | The Regents Of The University Of California | Proximal degas driven microfluidic actuation |
GB2516670A (en) * | 2013-07-29 | 2015-02-04 | Atlas Genetics Ltd | Fluid control device and method of manufacture |
BR102014031426B1 (pt) | 2014-12-15 | 2018-07-24 | Jjgc Ind E Comercio De Materiais Dentarios S/A | implante |
USD816841S1 (en) | 2014-12-15 | 2018-05-01 | Jjgc Industria E Comercio De Materiais Dentarios S/A | Bone implant |
EP3222351A1 (en) * | 2016-03-23 | 2017-09-27 | Ecole Polytechnique Fédérale de Lausanne (EPFL) | Microfluidic network device |
BR102016010184B1 (pt) | 2016-05-05 | 2020-10-27 | Jjgc Indústria E Comércio De Materiais Dentários S.A. | conjunto protético e processo para produção do mesmo |
DE102018124467A1 (de) * | 2018-10-04 | 2020-04-09 | Mst Innovation Gmbh | Hydraulisches Mikroventil |
US11236846B1 (en) * | 2019-07-11 | 2022-02-01 | Facebook Technologies, Llc | Fluidic control: using exhaust as a control mechanism |
US20210397259A1 (en) * | 2020-06-19 | 2021-12-23 | Facebook Technologies, Llc | Selective laser etching of layered fluidistors |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4139668A1 (de) * | 1991-12-02 | 1993-06-03 | Kernforschungsz Karlsruhe | Mikroventil und verfahren zu dessen herstellung |
DE4223067C2 (de) * | 1992-07-14 | 1997-08-07 | Univ Dresden Tech | Mikromechanischer Durchflußbegrenzer in Mehrschichtenstruktur |
SE501713C2 (sv) * | 1993-09-06 | 1995-05-02 | Pharmacia Biosensor Ab | Ventil av membrantyp, speciellt för vätskehanteringsblock med mikroflödeskanaler |
DE4422944A1 (de) * | 1994-06-30 | 1996-01-04 | Bosch Gmbh Robert | Mikroventil |
WO1999017749A1 (en) | 1997-10-02 | 1999-04-15 | Iep Group, Inc. | A micromachined valve for fluid applications |
DE19949912C2 (de) * | 1999-10-16 | 2003-02-27 | Karlsruhe Forschzent | Vorrichtung für eine Kraftübersetzung, Verfahren zu deren Herstellung und deren Verwendung |
DE10048376C2 (de) * | 2000-09-29 | 2002-09-19 | Fraunhofer Ges Forschung | Mikroventil mit einem normalerweise geschlossenen Zustand |
WO2002060582A2 (en) | 2000-11-16 | 2002-08-08 | Fluidigm Corporation | Microfluidic devices for introducing and dispensing fluids from microfluidic systems |
US6626417B2 (en) * | 2001-02-23 | 2003-09-30 | Becton, Dickinson And Company | Microfluidic valve and microactuator for a microvalve |
US20050266582A1 (en) * | 2002-12-16 | 2005-12-01 | Modlin Douglas N | Microfluidic system with integrated permeable membrane |
EP1594694A4 (en) * | 2002-12-30 | 2010-01-20 | Univ California | METHODS AND APPARATUS FOR DETECTION AND ANALYSIS OF PATHOGENIC AGENTS |
US7862000B2 (en) * | 2006-02-03 | 2011-01-04 | California Institute Of Technology | Microfluidic method and structure with an elastomeric gas-permeable gasket |
EP1905514A1 (en) * | 2006-09-30 | 2008-04-02 | Roche Diagnostics GmbH | Device having a reversibly closable fluid valve |
KR20100028526A (ko) | 2007-02-05 | 2010-03-12 | 마이크로칩 바이오테크놀로지스, 인크. | 마이크로유체 및 나노유체 장치, 시스템 및 응용 |
DK2408562T3 (en) | 2009-03-17 | 2018-06-06 | Menarini Silicon Biosystems Spa | Microfluidic device for isolating cells |
ITBO20090155A1 (it) | 2009-03-17 | 2010-09-18 | Silicon Biosystems Spa | Metodo per l'isolamento di particelle |
KR20120030130A (ko) * | 2009-06-02 | 2012-03-27 | 인터젠엑스 인크. | 다이아프램 밸브를 포함하는 유체 장치 |
KR20110136629A (ko) * | 2010-06-15 | 2011-12-21 | 삼성전자주식회사 | 마이크로 밸브를 갖는 미세 유체 소자 |
-
2009
- 2009-12-17 IT ITBO2009A000806A patent/IT1398480B1/it active
-
2010
- 2010-12-16 WO PCT/IB2010/003277 patent/WO2011073782A1/en active Application Filing
- 2010-12-16 EP EP10810876.2A patent/EP2513533B1/en active Active
- 2010-12-16 DK DK10810876.2T patent/DK2513533T3/en active
- 2010-12-16 US US13/515,959 patent/US9127783B2/en active Active
- 2010-12-16 ES ES10810876.2T patent/ES2557291T3/es active Active
Also Published As
Publication number | Publication date |
---|---|
WO2011073782A8 (en) | 2012-05-18 |
EP2513533B1 (en) | 2015-09-30 |
EP2513533A1 (en) | 2012-10-24 |
US20130045144A1 (en) | 2013-02-21 |
ITBO20090806A1 (it) | 2011-06-18 |
DK2513533T3 (en) | 2016-01-04 |
WO2011073782A1 (en) | 2011-06-23 |
ES2557291T3 (es) | 2016-01-25 |
US9127783B2 (en) | 2015-09-08 |
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