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IT1229658B - Analoghi della timopentina retro-inversi ad uno o piu' legami, il metodo per la loro sintesi ed il loro impiego per la preparazione di composizioni farmaceutiche. - Google Patents

Analoghi della timopentina retro-inversi ad uno o piu' legami, il metodo per la loro sintesi ed il loro impiego per la preparazione di composizioni farmaceutiche.

Info

Publication number
IT1229658B
IT1229658B IT8920257A IT2025789A IT1229658B IT 1229658 B IT1229658 B IT 1229658B IT 8920257 A IT8920257 A IT 8920257A IT 2025789 A IT2025789 A IT 2025789A IT 1229658 B IT1229658 B IT 1229658B
Authority
IT
Italy
Prior art keywords
analogues
thyopentine
links
synthesis
reverse
Prior art date
Application number
IT8920257A
Other languages
English (en)
Other versions
IT8920257A0 (it
Inventor
Sabina Mariotti
Alessandro Sisto
Luciano Nencioni
Luigi Villa
Antonio Silvio Verdini
Antonello Pessi
Original Assignee
Eniricerche Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eniricerche Spa filed Critical Eniricerche Spa
Priority to IT8920257A priority Critical patent/IT1229658B/it
Publication of IT8920257A0 publication Critical patent/IT8920257A0/it
Priority to AT90200954T priority patent/ATE133180T1/de
Priority to DE69024839T priority patent/DE69024839T2/de
Priority to EP90200954A priority patent/EP0393786B1/en
Priority to ES90200954T priority patent/ES2084647T3/es
Priority to CA002015053A priority patent/CA2015053A1/en
Priority to JP2103269A priority patent/JPH02292250A/ja
Application granted granted Critical
Publication of IT1229658B publication Critical patent/IT1229658B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/02—Linear peptides containing at least one abnormal peptide link
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0212—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -N-C-N-C(=0)-, e.g. retro-inverso peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IT8920257A 1989-04-21 1989-04-21 Analoghi della timopentina retro-inversi ad uno o piu' legami, il metodo per la loro sintesi ed il loro impiego per la preparazione di composizioni farmaceutiche. IT1229658B (it)

Priority Applications (7)

Application Number Priority Date Filing Date Title
IT8920257A IT1229658B (it) 1989-04-21 1989-04-21 Analoghi della timopentina retro-inversi ad uno o piu' legami, il metodo per la loro sintesi ed il loro impiego per la preparazione di composizioni farmaceutiche.
AT90200954T ATE133180T1 (de) 1989-04-21 1990-04-18 Retro-inverso-peptide, analoga von thymopenthin, die eine oder mehrere bindungen tragen, verfahren zu deren herstellung und deren verwendung zur zubereitung eines medikamentes
DE69024839T DE69024839T2 (de) 1989-04-21 1990-04-18 Retro-Inverso-Peptide, Analoga von Thymopenthin, die eine oder mehrere Bindungen tragen, Verfahren zu deren Herstellung und deren Verwendung zur Zubereitung eines Medikamentes
EP90200954A EP0393786B1 (en) 1989-04-21 1990-04-18 New retro-inverse, one- or more bond bearing analogues of thymopentin, a method for synthesizing the same and their employment for the preparation of pharmaceutical
ES90200954T ES2084647T3 (es) 1989-04-21 1990-04-18 Nuevos analogos de la timopentina que tienen uno o mas enlaces retroinvertidos, un metodo para sintetizarlos, y su empleo para la preparacion de productos farmaceuticos.
CA002015053A CA2015053A1 (en) 1989-04-21 1990-04-20 Retro-inverse, one- or more-bond bearing analogues of thymopentin, a method for synthesizing the same and their employment for the preparation of pharmaceutical
JP2103269A JPH02292250A (ja) 1989-04-21 1990-04-20 サイモペンチン類似体

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8920257A IT1229658B (it) 1989-04-21 1989-04-21 Analoghi della timopentina retro-inversi ad uno o piu' legami, il metodo per la loro sintesi ed il loro impiego per la preparazione di composizioni farmaceutiche.

Publications (2)

Publication Number Publication Date
IT8920257A0 IT8920257A0 (it) 1989-04-21
IT1229658B true IT1229658B (it) 1991-09-06

Family

ID=11165208

Family Applications (1)

Application Number Title Priority Date Filing Date
IT8920257A IT1229658B (it) 1989-04-21 1989-04-21 Analoghi della timopentina retro-inversi ad uno o piu' legami, il metodo per la loro sintesi ed il loro impiego per la preparazione di composizioni farmaceutiche.

Country Status (7)

Country Link
EP (1) EP0393786B1 (it)
JP (1) JPH02292250A (it)
AT (1) ATE133180T1 (it)
CA (1) CA2015053A1 (it)
DE (1) DE69024839T2 (it)
ES (1) ES2084647T3 (it)
IT (1) IT1229658B (it)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0556405A1 (en) * 1991-08-26 1993-08-25 Japan Tobacco Inc. Pseudopentapeptides with immunomodulating activity
RU2508295C2 (ru) 2012-03-22 2014-02-27 Общество с ограниченной ответственностью "Биофармокс" Синтетические пептиды с ненаркотическим типом анальгетического действия

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63221842A (ja) * 1987-03-11 1988-09-14 Nippon Steel Corp 金属粉体、金属化合物粉体およびセラミツクス粉体の製造方法および装置

Also Published As

Publication number Publication date
EP0393786A1 (en) 1990-10-24
DE69024839T2 (de) 1996-05-30
JPH02292250A (ja) 1990-12-03
ES2084647T3 (es) 1996-05-16
DE69024839D1 (de) 1996-02-29
CA2015053A1 (en) 1990-10-21
ATE133180T1 (de) 1996-02-15
IT8920257A0 (it) 1989-04-21
EP0393786B1 (en) 1996-01-17

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Legal Events

Date Code Title Description
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19961015