IT1217314B - Nonapeptide sintetico ad attivita'adiuvante capace di potenziare in vivo la risposta anticorporale - Google Patents

Nonapeptide sintetico ad attivita'adiuvante capace di potenziare in vivo la risposta anticorporale

Info

Publication number: IT1217314B
Authority: IT; Italy
Prior art keywords: vivo; corporal; response; enhancing; adjuvant activity
Prior art date: 1987-02-20

Application number

IT19434/87A

Other languages

English (en)

Other versions

IT8719434A0 (it

Inventor

Nencioni Luciano

Antoni Guiod

Boraschi Diana

Tagliabue Aldo

Original Assignee

Sclavo Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-02-20

Filing date

1987-02-20

Publication date

1990-03-22

1987-02-20 Application filed by Sclavo Spa filed Critical Sclavo Spa

1987-02-20 Priority to IT19434/87A priority Critical patent/IT1217314B/it

1987-02-20 Publication of IT8719434A0 publication Critical patent/IT8719434A0/it

1988-02-12 Priority to US07/156,301 priority patent/US5206014A/en

1988-02-16 Priority to EP88830056A priority patent/EP0293333B1/en

1988-02-16 Priority to AT88830056T priority patent/ATE95422T1/de

1988-02-16 Priority to DE88830056T priority patent/DE3884672T2/de

1988-02-16 Priority to ES88830056T priority patent/ES2059562T3/es

1988-02-20 Priority to JP63036513A priority patent/JPS63301829A/ja

1990-03-22 Application granted granted Critical

1990-03-22 Publication of IT1217314B publication Critical patent/IT1217314B/it

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/545—IL-1
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55516—Proteins; Peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Immunology (AREA)
General Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
Microbiology (AREA)
Molecular Biology (AREA)
Epidemiology (AREA)
Toxicology (AREA)
Zoology (AREA)
Gastroenterology & Hepatology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Mycology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Medicines Containing Plant Substances (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

IT19434/87A 1987-02-20 1987-02-20 Nonapeptide sintetico ad attivita'adiuvante capace di potenziare in vivo la risposta anticorporale IT1217314B (it)

Priority Applications (7)

Application Number	Priority Date	Filing Date	Title
IT19434/87A IT1217314B (it)	1987-02-20	1987-02-20	Nonapeptide sintetico ad attivita'adiuvante capace di potenziare in vivo la risposta anticorporale
US07/156,301 US5206014A (en)	1987-02-20	1988-02-12	Synthetic nonapeptide for use as an adjuvant
EP88830056A EP0293333B1 (en)	1987-02-20	1988-02-16	A synthetic nonapeptide of use as an adjuvant
AT88830056T ATE95422T1 (de)	1987-02-20	1988-02-16	Ein synthetisches nonapeptid zur verwendung als adjuvant.
DE88830056T DE3884672T2 (de)	1987-02-20	1988-02-16	Ein synthetisches Nonapeptid zur Verwendung als Adjuvant.
ES88830056T ES2059562T3 (es)	1987-02-20	1988-02-16	Un nonapeptido sintetico de uso como adyuvante.
JP63036513A JPS63301829A (ja)	1987-02-20	1988-02-20	合成ノナペプチドの補助薬としての使用

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
IT19434/87A IT1217314B (it)	1987-02-20	1987-02-20	Nonapeptide sintetico ad attivita'adiuvante capace di potenziare in vivo la risposta anticorporale

Publications (2)

Publication Number	Publication Date
IT8719434A0 IT8719434A0 (it)	1987-02-20
IT1217314B true IT1217314B (it)	1990-03-22

Family

ID=11157912

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IT19434/87A IT1217314B (it)	1987-02-20	1987-02-20	Nonapeptide sintetico ad attivita'adiuvante capace di potenziare in vivo la risposta anticorporale

Country Status (7)

Country	Link
US (1)	US5206014A (it)
EP (1)	EP0293333B1 (it)
JP (1)	JPS63301829A (it)
AT (1)	ATE95422T1 (it)
DE (1)	DE3884672T2 (it)
ES (1)	ES2059562T3 (it)
IT (1)	IT1217314B (it)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6432402B1 (en)	1989-05-25	2002-08-13	Sloan-Kettering Institute For Cancer Research	Anti-idiotypic antibody which induces an immune response against a glycosphingolipid and use thereof
DE69032855T2 (de) *	1989-05-25	1999-08-12	Sloan-Kettering Institute for Cancer Research, New York, N.Y.	Antiidiotypischer antikörper, der eine immunantwort gegen ein glykosphingolipid induziert und seine verwendung
IT1262898B (it) *	1992-03-23	1996-07-22		Antigeni ricombinanti proteici ad aumentata immunogenicita' contenenti il peptide rappresentato dalla sequenza vqgeesndk
US6270758B1 (en)	1998-10-08	2001-08-07	Duke University	Substantially non-toxic biologically active mucosal adjuvants in vertebrate subjects
WO2001039803A2 (en) *	1999-12-03	2001-06-07	Celltech Chiroscience Ltd.	Interleukin-1 muteins useful as vaccine adjuvants

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4283328A (en) *	1979-10-01	1981-08-11	Research Corporation	Preparation of dehydropeptides
EP0033384B1 (de) *	1980-01-18	1984-02-15	Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V.	Thymosin-alpha-1-Fragmente enthaltende Arzneimittel mit immunstimulierender Wirkung, und Thymosin-alpha-1-Fragmente
JPS57197223A (en) *	1981-05-27	1982-12-03	Eisai Co Ltd	Immunoenhancing agent containing ricin b chain
DE3224379A1 (de) *	1982-06-30	1984-01-12	Hoechst Ag, 6230 Frankfurt	Nonapeptid mit immunstimulierender wirkung, verfahren zu dessen herstellung und dessen verwendung
DE3230151A1 (de) *	1982-08-13	1984-02-16	Hoechst Ag, 6230 Frankfurt	Neues polypeptid mit wirkung auf das immunsystem, verfahren zu seiner isolierung und reinigung, seine verwendung, dieses enthaltende mittel sowie seine spaltprodukte, deren verwendung und diese enthaltende mittel
US4845079A (en) *	1985-01-23	1989-07-04	Luly Jay R	Peptidylaminodiols
IT1188550B (it) *	1986-02-07	1988-01-14	Sclavo Spa	Peptide sintetico ad attivita' interleukina 1 umana

1987
- 1987-02-20 IT IT19434/87A patent/IT1217314B/it active
1988
- 1988-02-12 US US07/156,301 patent/US5206014A/en not_active Expired - Fee Related
- 1988-02-16 AT AT88830056T patent/ATE95422T1/de not_active IP Right Cessation
- 1988-02-16 ES ES88830056T patent/ES2059562T3/es not_active Expired - Lifetime
- 1988-02-16 DE DE88830056T patent/DE3884672T2/de not_active Expired - Fee Related
- 1988-02-16 EP EP88830056A patent/EP0293333B1/en not_active Expired - Lifetime
- 1988-02-20 JP JP63036513A patent/JPS63301829A/ja active Pending

Also Published As

Publication number	Publication date
EP0293333B1 (en)	1993-10-06
IT8719434A0 (it)	1987-02-20
ES2059562T3 (es)	1994-11-16
US5206014A (en)	1993-04-27
EP0293333A3 (en)	1990-09-19
ATE95422T1 (de)	1993-10-15
DE3884672T2 (de)	1994-04-28
EP0293333A2 (en)	1988-11-30
JPS63301829A (ja)	1988-12-08
DE3884672D1 (de)	1993-11-11

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