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IT1204494B - Derivati della 1-stirene solfonil 2-osso 5-alcossi pirrolidina,loro procedimento di preparazione e loro applicazione come farmaci - Google Patents

Derivati della 1-stirene solfonil 2-osso 5-alcossi pirrolidina,loro procedimento di preparazione e loro applicazione come farmaci

Info

Publication number
IT1204494B
IT1204494B IT19916/86A IT1991686A IT1204494B IT 1204494 B IT1204494 B IT 1204494B IT 19916/86 A IT19916/86 A IT 19916/86A IT 1991686 A IT1991686 A IT 1991686A IT 1204494 B IT1204494 B IT 1204494B
Authority
IT
Italy
Prior art keywords
alcoss
pyrolidine
drugs
bone
derivatives
Prior art date
Application number
IT19916/86A
Other languages
English (en)
Other versions
IT8619916A0 (it
Inventor
Emilio Toja
Carlo Zirotti
Giulio Galliani
Fernando Barzaghi
Original Assignee
Roussel Maestretti Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Maestretti Spa filed Critical Roussel Maestretti Spa
Publication of IT8619916A0 publication Critical patent/IT8619916A0/it
Priority to IT19916/86A priority Critical patent/IT1204494B/it
Priority to ZA871804A priority patent/ZA871804B/xx
Priority to PT84475A priority patent/PT84475B/pt
Priority to JP62068156A priority patent/JPS62270558A/ja
Priority to EP87400689A priority patent/EP0239500B1/fr
Priority to AT87400689T priority patent/ATE71936T1/de
Priority to US07/030,113 priority patent/US4810722A/en
Priority to HU871323A priority patent/HU198181B/hu
Priority to DE8787400689T priority patent/DE3776171D1/de
Priority to ES198787400689T priority patent/ES2038191T3/es
Priority to AU70737/87A priority patent/AU591255B2/en
Priority to FI871353A priority patent/FI81782C/fi
Priority to KR870002830A priority patent/KR870008840A/ko
Priority to MX005785A priority patent/MX173415B/es
Priority to CA000533227A priority patent/CA1282072C/fr
Priority to IE79387A priority patent/IE60102B1/en
Priority to DK157487A priority patent/DK157487A/da
Application granted granted Critical
Publication of IT1204494B publication Critical patent/IT1204494B/it
Priority to GR910402205T priority patent/GR3003643T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/46—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with hetero atoms directly attached to the ring nitrogen atom
    • C07D207/48—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IT19916/86A 1986-03-28 1986-03-28 Derivati della 1-stirene solfonil 2-osso 5-alcossi pirrolidina,loro procedimento di preparazione e loro applicazione come farmaci IT1204494B (it)

Priority Applications (18)

Application Number Priority Date Filing Date Title
IT19916/86A IT1204494B (it) 1986-03-28 1986-03-28 Derivati della 1-stirene solfonil 2-osso 5-alcossi pirrolidina,loro procedimento di preparazione e loro applicazione come farmaci
ZA871804A ZA871804B (en) 1986-03-28 1987-03-12 Derivatives of 1-styrenesulphonyl-2-oxo-5-hydroxy pyrrolidine,the process and the intermediates for their preparations,their application as medicaments and the compositions containing them
PT84475A PT84475B (pt) 1986-03-28 1987-03-13 Processo para a preparacao de novos derivados da 1-stireno-sulfonil-2-oxo-5-hidroxi-pirrolidina
JP62068156A JPS62270558A (ja) 1986-03-28 1987-03-24 新規の１−スチレンスルホニル−２−オキソ−５−ヒドロキシピロリジン誘導体、それらの製造方法、それらの製造用中間体、それらの医薬としての使用及びそれらを含有する製薬組成物
DE8787400689T DE3776171D1 (de) 1986-03-28 1987-03-26 1-styrensulfonyl-2-oxo-5-hydroxy-pyrrolidine, ihre vorprodukte und verfahren zur herstellung, sie enthaltende zusammensetzungen und ihre anwendung als heilmittel.
AT87400689T ATE71936T1 (de) 1986-03-28 1987-03-26 1-styrensulfonyl-2-oxo-5-hydroxy-pyrrolidine, ihre vorprodukte und verfahren zur herstellung, sie enthaltende zusammensetzungen und ihre anwendung als heilmittel.
US07/030,113 US4810722A (en) 1986-03-28 1987-03-26 1-styrenesulphonyl-2-oxo-5-hydroxy pyrrolidines and their use for memory restoration after electoshock treatment
HU871323A HU198181B (en) 1986-03-28 1987-03-26 Process for producing 1-styrenesulfinyl-2-oxo-5-hydroxypyrrolidine derivatives and pharmaceutical compositions comprising same
EP87400689A EP0239500B1 (fr) 1986-03-28 1987-03-26 Dérivés de la 1-styrène sulfonyl 2-oxo 5-hydroxy pyrrolidine, leur procédé et des intermédiaires de préparation, leur application comme médicaments et les compositions les renfermant
ES198787400689T ES2038191T3 (es) 1986-03-28 1987-03-26 Procedimiento para preparar derivados de 1-estirenosulfonil-2-oxo-5-hidroxi-pirrolidina.
FI871353A FI81782C (fi) 1986-03-28 1987-03-27 Foerfarande foer framstaellning av nya terapeutiskt anvaendbara 1-styrensulfonyl-2-oxo-5-hydroxi-pyrrolidinderivat.
AU70737/87A AU591255B2 (en) 1986-03-28 1987-03-27 New derivatives of 1-styrenesulphonyl-2-oxo-5-hydroxy pyrrolidine, the process and the intermediates for their preparations, their application as medicaments and the compositions containing them
KR870002830A KR870008840A (ko) 1986-03-28 1987-03-27 1-스티렌술포닐-2-옥소-5-히드록시 피롤리딘 유도체의 제조방법
MX005785A MX173415B (es) 1986-03-28 1987-03-27 Procedimiento de preparacion de nuevos derivados de 1-estireno sulfonil-2-oxo 5-hidroxi pirrolidina y producto obtenido
CA000533227A CA1282072C (fr) 1986-03-28 1987-03-27 Derives de la 1-styrene sulfonyl 2-oxo 5-hydroxy pyrrolidine, leur procede et des intermediaires de preparation, leur application comme medicaments et les compositions les renfermant
IE79387A IE60102B1 (en) 1986-03-28 1987-03-27 New derivatives of 1-styrenesulphonyl-2-oxo-5-hydroxy pyrrolidine, the process and the intermediates for their preparation, their application as medicaments and the compositions containing them
DK157487A DK157487A (da) 1986-03-28 1987-03-27 1-styrensulfonyl-2-oxo-5-hydroxypyrrolidinderivater og praeparater med indhold deraf samt fremgangsmaade til deres fremstilling
GR910402205T GR3003643T3 (it) 1986-03-28 1992-01-23

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT19916/86A IT1204494B (it) 1986-03-28 1986-03-28 Derivati della 1-stirene solfonil 2-osso 5-alcossi pirrolidina,loro procedimento di preparazione e loro applicazione come farmaci

Publications (2)

Publication Number Publication Date
IT8619916A0 IT8619916A0 (it) 1986-03-28
IT1204494B true IT1204494B (it) 1989-03-01

Family

ID=11162311

Family Applications (1)

Application Number Title Priority Date Filing Date
IT19916/86A IT1204494B (it) 1986-03-28 1986-03-28 Derivati della 1-stirene solfonil 2-osso 5-alcossi pirrolidina,loro procedimento di preparazione e loro applicazione come farmaci

Country Status (18)

Country Link
US (1) US4810722A (it)
EP (1) EP0239500B1 (it)
JP (1) JPS62270558A (it)
KR (1) KR870008840A (it)
AT (1) ATE71936T1 (it)
AU (1) AU591255B2 (it)
CA (1) CA1282072C (it)
DE (1) DE3776171D1 (it)
DK (1) DK157487A (it)
ES (1) ES2038191T3 (it)
FI (1) FI81782C (it)
GR (1) GR3003643T3 (it)
HU (1) HU198181B (it)
IE (1) IE60102B1 (it)
IT (1) IT1204494B (it)
MX (1) MX173415B (it)
PT (1) PT84475B (it)
ZA (1) ZA871804B (it)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2873898B2 (ja) * 1992-04-13 1999-03-24 富山化学工業株式会社 ベンゾ［ｂ］チオフェン−５−イル誘導体もしくはその光学活性体またはそれらの塩並びにそれらの製造法
ES2107376B1 (es) * 1995-08-02 1998-07-01 Uriach & Cia Sa J Nuevos derivados de pirimidona con actividad antifungica.
BR9606546A (pt) * 1995-08-02 1998-07-14 Uriach & Cia Sa J Novas carboxamidas com atividade fungicida

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3453289A (en) * 1966-01-21 1969-07-01 American Home Prod P-substituted-phenylsulfonyl pyrrolidine derivatives
US3423426A (en) * 1966-01-25 1969-01-21 Chevron Res N-(polyhaloalkylthio) alkenylsuccinimides
US3686169A (en) * 1970-07-20 1972-08-22 Monsanto Co Thiocycloamides
JPS5822111B2 (ja) * 1977-10-29 1983-05-06 協和醗酵工業株式会社 柑橘類果実の改質剤
FR2553409B1 (fr) * 1983-10-18 1986-04-18 Choay Sa Nouveaux benzenesulfonyl-lactames, leur procede de preparation et leur application comme substance active de compositions pharmaceutiques
DK167393B1 (da) * 1985-12-30 1993-10-25 Roussel Uclaf 1-sulfonyl-2-oxo-pyrrolidinderivater, deres fremstilling og farmaceutiske praeparater med indhold deraf

Also Published As

Publication number Publication date
DK157487A (da) 1987-09-29
IT8619916A0 (it) 1986-03-28
HU198181B (en) 1989-08-28
AU7073787A (en) 1987-10-01
MX173415B (es) 1994-03-03
IE870793L (en) 1987-09-28
IE60102B1 (en) 1994-06-01
JPS62270558A (ja) 1987-11-24
PT84475A (fr) 1987-04-01
PT84475B (pt) 1989-11-10
MX5785A (es) 1993-10-01
EP0239500B1 (fr) 1992-01-22
HUT43816A (en) 1987-12-28
FI871353A0 (fi) 1987-03-27
CA1282072C (fr) 1991-03-26
ES2038191T3 (es) 1993-07-16
DK157487D0 (da) 1987-03-27
FI81782C (fi) 1990-12-10
ZA871804B (en) 1988-05-25
FI871353A (fi) 1987-09-29
US4810722A (en) 1989-03-07
EP0239500A3 (en) 1988-07-27
DE3776171D1 (de) 1992-03-05
AU591255B2 (en) 1989-11-30
GR3003643T3 (it) 1993-03-16
KR870008840A (ko) 1987-10-21
ATE71936T1 (de) 1992-02-15
EP0239500A2 (fr) 1987-09-30
FI81782B (fi) 1990-08-31

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