IT1202370B - Soluzioni inietabili in cui l'atti vita' emolitica degli agenti di formazione di micelle naturali e' evitata mediante l'aggiunta di lipoidi e relativi prodotti - Google Patents
Soluzioni inietabili in cui l'atti vita' emolitica degli agenti di formazione di micelle naturali e' evitata mediante l'aggiunta di lipoidi e relativi prodottiInfo
- Publication number
- IT1202370B IT1202370B IT25194/77A IT2519477A IT1202370B IT 1202370 B IT1202370 B IT 1202370B IT 25194/77 A IT25194/77 A IT 25194/77A IT 2519477 A IT2519477 A IT 2519477A IT 1202370 B IT1202370 B IT 1202370B
- Authority
- IT
- Italy
- Prior art keywords
- emolithic
- lipoids
- avoided
- life
- addition
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- General Health & Medical Sciences (AREA)
- Dispersion Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Biophysics (AREA)
- Animal Behavior & Ethology (AREA)
- Molecular Biology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AT511176A AT352881B (de) | 1976-07-12 | 1976-07-12 | Verfahren zur herstellung von injektions- loesungen |
CH699477A CH628811A5 (en) | 1976-07-12 | 1977-06-07 | Injection solutions |
Publications (1)
Publication Number | Publication Date |
---|---|
IT1202370B true IT1202370B (it) | 1989-02-09 |
Family
ID=25601846
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT25194/77A IT1202370B (it) | 1976-07-12 | 1977-06-29 | Soluzioni inietabili in cui l'atti vita' emolitica degli agenti di formazione di micelle naturali e' evitata mediante l'aggiunta di lipoidi e relativi prodotti |
Country Status (18)
Country | Link |
---|---|
US (1) | US4158707A (it) |
JP (1) | JPS6051448B2 (it) |
AU (1) | AU517249B2 (it) |
CA (1) | CA1082596A (it) |
DE (1) | DE2730570A1 (it) |
DK (1) | DK149483C (it) |
FR (2) | FR2358161A1 (it) |
GB (1) | GB1587076A (it) |
HK (1) | HK26584A (it) |
IE (1) | IE46037B1 (it) |
IL (1) | IL52458A (it) |
IT (1) | IT1202370B (it) |
LU (2) | LU77708A1 (it) |
MY (1) | MY8500263A (it) |
NL (1) | NL189072C (it) |
NZ (1) | NZ184564A (it) |
PH (1) | PH16333A (it) |
SE (1) | SE448516B (it) |
Families Citing this family (58)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2914788A1 (de) * | 1979-04-11 | 1980-10-16 | Nattermann A & Cie | Parenteral applizierbare, stabile arzneimittelloesungen mit entzuendungshemmender wirkung |
CA1173360A (en) * | 1979-06-22 | 1984-08-28 | Jurg Schrank | Pharmaceutical preparations |
US4264583A (en) * | 1979-07-25 | 1981-04-28 | The Procter & Gamble Company | Gallstone dissolution compositions and method |
JPS57163313A (en) * | 1981-03-31 | 1982-10-07 | Nippon Shinyaku Co Ltd | Vitamin e pharmaceutical and its preparation |
JPH0768117B2 (ja) * | 1983-05-06 | 1995-07-26 | ベスター・インコーポレイテツド | 薬剤放出調整用小胞製剤 |
IL72420A (en) * | 1983-07-22 | 1987-10-30 | Hoffmann La Roche | Aqueous vitamin e solutions and their manufacture |
JPH0818989B2 (ja) * | 1984-01-12 | 1996-02-28 | 株式会社ミドリ十字 | 脂肪乳剤中のプロスタグランジンの安定化方法 |
CA1264162A (en) * | 1984-03-15 | 1990-01-02 | Manfred Breuninger | Glycerol ether phosphatides |
US5002936A (en) * | 1985-04-12 | 1991-03-26 | Seymour Lieberman | Lipophilic complexes of pharmacologically active inorganic mineral acid esters of organic compounds |
US4831018A (en) * | 1985-05-17 | 1989-05-16 | Smithkline Beckman Corporation | Polyene antibiotic emulsion formulation |
DD286971A5 (de) * | 1985-08-02 | 1991-02-14 | Merz U. Co. Gmbh U. Co.,De | Antivirale und antitumor-zusammensetzung, verfahren zu deren herstellung und deren verwendung |
US5023271A (en) * | 1985-08-13 | 1991-06-11 | California Biotechnology Inc. | Pharmaceutical microemulsions |
SE8505047L (sv) * | 1985-10-25 | 1987-04-26 | Nutritional Int Res Inst | Fettemulsion |
CA1319886C (en) | 1987-02-03 | 1993-07-06 | Alberto Ferro | Mixed micelle solutions |
DE3903753A1 (de) * | 1989-02-06 | 1990-08-23 | Schering Ag | Verfahren zur herstellung waessriger mischmicelloesungen |
NZ232865A (en) * | 1989-03-21 | 1992-07-28 | Hoffmann La Roche | A mixed-micelle solution comprising a micelle former and an immunomodulator |
US5085864A (en) * | 1989-10-30 | 1992-02-04 | Abbott Laboratories | Injectable formulation for lipophilic drugs |
DE3938030A1 (de) * | 1989-11-13 | 1991-05-16 | Schering Ag | Verfahren zur herstellung waessriger mischmicelloesungen |
CA2033725C (en) * | 1990-01-24 | 2001-05-29 | Folker Pittrof | Pharmaceutical and cosmetic compositions containing a salt of cholanic acid |
CA2033714A1 (en) * | 1990-01-25 | 1991-07-26 | Alberto Ferro | Pharmaceutical preparations |
FR2663224B1 (fr) * | 1990-06-14 | 1995-01-20 | Applicationes Farmaceuticas Sa | Forme galenique parenterale. |
DE4122661C2 (de) * | 1990-08-06 | 1996-07-11 | Nattermann A & Cie | Pharmazeutisches Produkt zur Behandlung von Pneumocystis-carinii-Pneumonie |
EP0471309A1 (de) * | 1990-08-17 | 1992-02-19 | F. Hoffmann-La Roche Ag | Verwendung von Mischmicellen |
CA2444071C (en) * | 1991-02-08 | 2008-10-07 | Wellstat Therapeutics Corporation | Oxypurine nucleosides and their congeners, and acyl derivatives thereof, for improvement of hematopoiesis |
DE4336434A1 (de) * | 1993-10-26 | 1995-04-27 | Hoechst Ag | Pharmazeutische Zubereitung für die parenterale, enterale und dermale Verabreichung von praktisch unlöslichen Arzneistoffen und Verfahren zu ihrer Herstellung |
EP0682943B1 (de) * | 1994-05-20 | 2003-08-20 | GESELLSCHAFT FÜR MEDIZINISCHE FORSCHUNG UND WEITERBILDUNG e.V. GMF | Lormetazepamhaltige Öl-in-Wasser-Emulsion |
GB9426104D0 (en) * | 1994-12-23 | 1995-02-22 | Merck Sharp & Dohme | Use of surfactants and emulsions |
JP2740153B2 (ja) * | 1995-03-07 | 1998-04-15 | エフ・ホフマン−ラ ロシユ アーゲー | 混合ミセル |
US5759445A (en) * | 1995-05-24 | 1998-06-02 | Matsushita Electric Industrial Co., Ltd. | Lipid-dispersed solution and process for producing the same |
GB2326337A (en) * | 1997-06-20 | 1998-12-23 | Phares Pharma Holland | Homogeneous lipid compositions for drug delivery |
US6350738B1 (en) | 1998-03-06 | 2002-02-26 | Brigham Young University | Steroid derived antibiotics |
US6767904B2 (en) | 1998-03-06 | 2004-07-27 | Bringham Young University | Steroid derived antibiotics |
JP2004524368A (ja) * | 2001-03-27 | 2004-08-12 | フェアーズ ファーマシューティカル リサーチ エヌ.ヴェー. | 低い水溶性を有する生物学的に活性な化合物を可溶化するための方法および組成物 |
EP1730516A1 (en) * | 2004-03-30 | 2006-12-13 | Pfizer Products Incorporated | Method and device for evaluation of pharmaceutical compositions |
US20060127468A1 (en) * | 2004-05-19 | 2006-06-15 | Kolodney Michael S | Methods and related compositions for reduction of fat and skin tightening |
US7754230B2 (en) * | 2004-05-19 | 2010-07-13 | The Regents Of The University Of California | Methods and related compositions for reduction of fat |
TR201802446T4 (tr) * | 2004-05-19 | 2018-03-21 | Los Angeles Biomedical Res Inst Harbor Ucla Medical Ct | Sodyum deoksikolat içeren enjeksiyonluk bileşim. |
US20100062073A1 (en) * | 2006-11-29 | 2010-03-11 | Ronald Arthur Beyerinck | Pharmaceutical compositions comprising nanoparticles comprising enteric polymers casein |
US20100119612A1 (en) * | 2007-04-17 | 2010-05-13 | Bend Research, Inc | Nanoparticles comprising non-crystalline drug |
WO2008135828A2 (en) * | 2007-05-03 | 2008-11-13 | Pfizer Products Inc. | Nanoparticles comprising a drug, ethylcellulose, and a bile salt |
WO2008135855A2 (en) * | 2007-05-03 | 2008-11-13 | Pfizer Products Inc. | Nanoparticles comprising a cholesteryl ester transfer protein inhibitor and a nonionizable polymer |
US20100080852A1 (en) * | 2007-05-03 | 2010-04-01 | Ronald Arthur Beyerinck | Phamaceutical composition comprising nanoparticles and casein |
WO2008149230A2 (en) | 2007-06-04 | 2008-12-11 | Pfizer Products Inc. | Nanoparticles comprising drug, a non-ionizable cellulosic polymer and tocopheryl polyethylene glycol succinate |
US8974827B2 (en) * | 2007-06-04 | 2015-03-10 | Bend Research, Inc. | Nanoparticles comprising a non-ionizable cellulosic polymer and an amphiphilic non-ionizable block copolymer |
US20100215747A1 (en) * | 2007-07-13 | 2010-08-26 | Corey Jay Bloom | Nanoparticles comprising ionizable, poorly water soluble cellulosic polymers |
EP2231169B1 (en) * | 2007-12-06 | 2016-05-04 | Bend Research, Inc. | Pharmaceutical compositions comprising nanoparticles and a resuspending material |
US9233078B2 (en) * | 2007-12-06 | 2016-01-12 | Bend Research, Inc. | Nanoparticles comprising a non-ionizable polymer and an Amine-functionalized methacrylate copolymer |
US8101593B2 (en) | 2009-03-03 | 2012-01-24 | Kythera Biopharmaceuticals, Inc. | Formulations of deoxycholic acid and salts thereof |
CN102058528B (zh) * | 2009-11-13 | 2012-12-12 | 中国科学院上海药物研究所 | 一种黄豆苷元胶束及其制备方法 |
GB2480632A (en) | 2010-05-25 | 2011-11-30 | Kythera Biopharmaceuticals Inc | Preparation of 12-keto and 12-alpha-hydroxy steroids |
EP2675460A4 (en) | 2011-02-18 | 2014-07-09 | Kythera Biopharmaceuticals Inc | TREATMENT OF FAT TISSUE UNDER CHIN |
US8653058B2 (en) | 2011-04-05 | 2014-02-18 | Kythera Biopharmaceuticals, Inc. | Compositions comprising deoxycholic acid and salts thereof suitable for use in treating fat deposits |
RU2682249C2 (ru) * | 2012-05-31 | 2019-03-18 | Терумо Кабусики Кайся | рН-ЧУВСТВИТЕЛЬНЫЙ НОСИТЕЛЬ И СПОСОБ ЕГО ПОЛУЧЕНИЯ, И рН-ЧУВСТВИТЕЛЬНОЕ ЛЕКАРСТВЕННОЕ СРЕДСТВО, И рН-ЧУВСТВИТЕЛЬНАЯ ЛЕКАРСТВЕННАЯ КОМПОЗИЦИЯ, ГДЕ КАЖДОЕ ИЗ НИХ СОДЕРЖИТ НОСИТЕЛЬ, И СПОСОБ КУЛЬТИВИРОВАНИЯ С ИХ ПРИМЕНЕНИЕМ |
US9321749B1 (en) | 2012-07-25 | 2016-04-26 | Globavir Biosciences, Inc. | Heterocyclic compounds and uses thereof |
JP6154025B2 (ja) | 2012-12-24 | 2017-06-28 | ニューロガストルクス,インコーポレイテッド | Gi管障害を治療するための方法 |
US9844554B2 (en) | 2014-06-24 | 2017-12-19 | Neurogastrx, Inc. | Prodrugs of metopimazine |
CN110876719B (zh) * | 2018-09-06 | 2022-08-09 | 中国人民解放军军事科学院军事医学研究院 | 一种维生素k1注射剂及其制备方法 |
US10836757B1 (en) | 2020-04-02 | 2020-11-17 | Neurogastrx, Inc. | Polymorphic forms of metopimazine |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE575616C (de) * | 1928-12-14 | 1933-04-29 | Hans Much Dr | Verfahren zur Herstellung bestaendiger, klarer, waessriger Loesungen von Lipoiden, Fetten oder Harzen |
DE932083C (de) * | 1954-03-31 | 1955-08-22 | Upha Chem Pharm Praeparate G M | Verfahren zur Herstellung stabiler waessriger Injektionsloesungen von 2-Methyl-5, 8-dimethoxy-furanochromon |
US3044931A (en) * | 1960-01-27 | 1962-07-17 | Geigy Chem Corp | Aryloxy acetic acid amides: process for parenteral application |
NL260444A (it) * | 1960-12-05 | |||
US3639597A (en) * | 1968-02-02 | 1972-02-01 | Merck & Co Inc | Pharmaceutical compositions containing cholanic acid conjugates |
GB1317184A (en) * | 1969-06-20 | 1973-05-16 | Glaxo Lab Ltd | Steroid-containing pharmaceutical preparations |
US3900561A (en) * | 1970-12-17 | 1975-08-19 | Glaxo Lab Ltd | Pharmaceutical compositions |
US3917830A (en) * | 1970-12-17 | 1975-11-04 | Glaxo Lab Ltd | Steroidal anaesthetic composition for intraveneous injection |
AU461715B2 (en) * | 1972-01-21 | 1975-05-19 | American Home Products Corporation | Parenteral benzodiazepine compositions |
US4017616A (en) * | 1972-01-21 | 1977-04-12 | American Home Products Corporation | Parenteral benzodiazepine compositions |
DE2315609A1 (de) * | 1973-03-29 | 1974-10-17 | Holzhueter Hermann | Verfahren zum loesen von indomethacin in wasser und eine indomethacin enthaltende pharmazeutische zubereitung zur parenteralen applikation |
DE2433173C3 (de) * | 1974-07-10 | 1980-02-07 | J. Pfrimmer & Co, 8520 Erlangen | Verwendung von Cholansaurederivaten |
-
1977
- 1977-06-29 IT IT25194/77A patent/IT1202370B/it active Protection Beyond IP Right Term
- 1977-07-05 NZ NZ184564A patent/NZ184564A/xx unknown
- 1977-07-05 IL IL52458A patent/IL52458A/xx unknown
- 1977-07-06 DE DE19772730570 patent/DE2730570A1/de active Granted
- 1977-07-06 IE IE1403/77A patent/IE46037B1/en not_active IP Right Cessation
- 1977-07-07 AU AU26846/77A patent/AU517249B2/en not_active Expired
- 1977-07-07 FR FR7720957A patent/FR2358161A1/fr active Granted
- 1977-07-08 NL NLAANVRAGE7707641,A patent/NL189072C/xx not_active IP Right Cessation
- 1977-07-08 LU LU77708A patent/LU77708A1/xx unknown
- 1977-07-08 CA CA282,347A patent/CA1082596A/en not_active Expired
- 1977-07-08 US US05/813,913 patent/US4158707A/en not_active Expired - Lifetime
- 1977-07-08 JP JP52081110A patent/JPS6051448B2/ja not_active Expired
- 1977-07-11 DK DK314777A patent/DK149483C/da not_active Application Discontinuation
- 1977-07-11 GB GB29006/77A patent/GB1587076A/en not_active Expired
- 1977-07-11 SE SE7708059A patent/SE448516B/xx not_active IP Right Cessation
- 1977-07-12 PH PH19986A patent/PH16333A/en unknown
-
1978
- 1978-12-28 FR FR7836690A patent/FR2423219A1/fr active Granted
-
1984
- 1984-03-22 HK HK265/84A patent/HK26584A/xx unknown
-
1985
- 1985-12-30 MY MY263/85A patent/MY8500263A/xx unknown
-
1997
- 1997-03-12 LU LU90037C patent/LU90037I2/fr unknown
Also Published As
Publication number | Publication date |
---|---|
FR2423219A1 (fr) | 1979-11-16 |
IL52458A0 (en) | 1977-10-31 |
GB1587076A (en) | 1981-03-25 |
FR2358161B1 (it) | 1980-07-25 |
DE2730570A1 (de) | 1978-01-19 |
FR2423219B1 (it) | 1980-10-24 |
NZ184564A (en) | 1979-12-11 |
LU77708A1 (it) | 1978-09-14 |
DK314777A (da) | 1978-01-13 |
DK149483C (da) | 1986-12-15 |
SE7708059L (sv) | 1978-01-13 |
IE771403L (en) | 1978-01-12 |
IL52458A (en) | 1980-10-26 |
AU517249B2 (en) | 1981-07-16 |
DE2730570C2 (it) | 1989-01-19 |
FR2358161A1 (fr) | 1978-02-10 |
NL189072B (nl) | 1992-08-03 |
MY8500263A (en) | 1985-12-31 |
SE448516B (sv) | 1987-03-02 |
NL7707641A (nl) | 1978-01-16 |
JPS6051448B2 (ja) | 1985-11-14 |
IE46037B1 (en) | 1983-02-09 |
AU2684677A (en) | 1979-01-11 |
NL189072C (nl) | 1993-01-04 |
US4158707A (en) | 1979-06-19 |
HK26584A (en) | 1984-03-30 |
PH16333A (en) | 1983-09-05 |
DK149483B (da) | 1986-06-30 |
JPS539314A (en) | 1978-01-27 |
LU90037I2 (fr) | 1997-06-13 |
CA1082596A (en) | 1980-07-29 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ITCP | Complementary protection certificate |
Free format text: CCP 176 |
|
MEDD | Supplementary protection certificate for pharmaceutical products: granted |
Free format text: CCP 176, 19920428; F. HOFFMANN-LA ROCHE AG. |
|
TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19960628 |