IT1201474B - Derivati macromolecolarizzati di cdp-colina,procedimento per la loro preparazione e composizioni farmaceutiche che li contengono - Google Patents
Derivati macromolecolarizzati di cdp-colina,procedimento per la loro preparazione e composizioni farmaceutiche che li contengonoInfo
- Publication number
- IT1201474B IT1201474B IT22327/85A IT2232785A IT1201474B IT 1201474 B IT1201474 B IT 1201474B IT 22327/85 A IT22327/85 A IT 22327/85A IT 2232785 A IT2232785 A IT 2232785A IT 1201474 B IT1201474 B IT 1201474B
- Authority
- IT
- Italy
- Prior art keywords
- cdp
- derivatives
- macromolecularized
- colina
- procedure
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
- C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/58—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Gastroenterology & Hepatology (AREA)
- Cardiology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Saccharide Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
Priority Applications (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT22327/85A IT1201474B (it) | 1985-10-01 | 1985-10-01 | Derivati macromolecolarizzati di cdp-colina,procedimento per la loro preparazione e composizioni farmaceutiche che li contengono |
JP61231069A JPS62129296A (ja) | 1985-10-01 | 1986-09-29 | 巨大分子cdp−コリン誘導体、その製造方法及びこれを含有する薬剤組成物 |
US06/913,841 US4772463A (en) | 1985-10-01 | 1986-09-30 | Macromolecular CDP-choline derivatives, process for their preparation and pharmaceutical compositions containing them |
AT86113539T ATE48231T1 (de) | 1985-10-01 | 1986-10-01 | Makromolekulare cdp-cholinderivate, verfahren zu deren herstellung sowie diese enthaltende arzneimittel. |
ES86113539T ES2011767B3 (es) | 1985-10-01 | 1986-10-01 | Derivados macromoleculares de cdp-colina, procedimiento para su preparacion, y composiciones farmaceuticas que los contienen. |
EP86113539A EP0218190B1 (en) | 1985-10-01 | 1986-10-01 | Macromolecular cdp-choline derivatives, process for their preparation and pharmaceutical compositions containing them |
DE8686113539T DE3667139D1 (de) | 1985-10-01 | 1986-10-01 | Makromolekulare cdp-cholinderivate, verfahren zu deren herstellung sowie diese enthaltende arzneimittel. |
GR89400263T GR3000235T3 (en) | 1985-10-01 | 1989-11-30 | Macromolecular cdp-choline derivatives, process for their preparation and pharmaceutical compositions containing them |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT22327/85A IT1201474B (it) | 1985-10-01 | 1985-10-01 | Derivati macromolecolarizzati di cdp-colina,procedimento per la loro preparazione e composizioni farmaceutiche che li contengono |
Publications (2)
Publication Number | Publication Date |
---|---|
IT8522327A0 IT8522327A0 (it) | 1985-10-01 |
IT1201474B true IT1201474B (it) | 1989-02-02 |
Family
ID=11194722
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT22327/85A IT1201474B (it) | 1985-10-01 | 1985-10-01 | Derivati macromolecolarizzati di cdp-colina,procedimento per la loro preparazione e composizioni farmaceutiche che li contengono |
Country Status (8)
Country | Link |
---|---|
US (1) | US4772463A (it) |
EP (1) | EP0218190B1 (it) |
JP (1) | JPS62129296A (it) |
AT (1) | ATE48231T1 (it) |
DE (1) | DE3667139D1 (it) |
ES (1) | ES2011767B3 (it) |
GR (1) | GR3000235T3 (it) |
IT (1) | IT1201474B (it) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0408668B1 (en) * | 1988-10-27 | 1994-05-11 | Massachusetts Institute Of Technology | Process for increasing phosphatidylcholine in vivo |
EP0506979B1 (en) * | 1990-10-24 | 2001-07-11 | Masayuki Kuzuya | Organic polymer compound and production thereof |
CN1208064C (zh) * | 1997-12-24 | 2005-06-29 | 英特纳龙制药公司 | 高水合化胞磷胆碱、方法和应用 |
ES2425114T3 (es) | 2000-03-16 | 2013-10-11 | The Mclean Hospital Corporation | CDP-colina y uridina para el tratamiento del abuso del acohol |
CN100430066C (zh) | 2002-11-08 | 2008-11-05 | 麦克莱恩医院 | 用于烟草依赖性和戒断治疗的化合物 |
US7737128B2 (en) | 2004-06-10 | 2010-06-15 | The Mclean Hospital Corporation | Pyrimidines, such as uridine, in treatments for patients with bipolar disorder |
WO2006020703A1 (en) | 2004-08-11 | 2006-02-23 | The Mclean Hospital Corporation | Compounds for the treatment of marihuana dependence, withdrawal, and usage |
CN103509073B (zh) * | 2013-08-29 | 2016-01-06 | 洪军 | 一种胞磷胆碱钠化合物 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2402664A1 (fr) * | 1977-09-07 | 1979-04-06 | Agronomique Inst Nat Rech | Produits de couplage phosphorylcholine, composes amines procede d'obtention et applications |
IT1207106B (it) * | 1980-04-18 | 1989-05-17 | Made Italiana Srl Ora Searle I | Preparazione farmaceutica contenente citidin disfofocolina assorbibile per via orale |
JPS5821426A (ja) * | 1981-07-30 | 1983-02-08 | Teijin Ltd | 細胞毒性物質を結合した重合体を活性成分とする抗腫瘍剤およびその製造法 |
-
1985
- 1985-10-01 IT IT22327/85A patent/IT1201474B/it active
-
1986
- 1986-09-29 JP JP61231069A patent/JPS62129296A/ja active Pending
- 1986-09-30 US US06/913,841 patent/US4772463A/en not_active Expired - Fee Related
- 1986-10-01 AT AT86113539T patent/ATE48231T1/de not_active IP Right Cessation
- 1986-10-01 ES ES86113539T patent/ES2011767B3/es not_active Expired - Lifetime
- 1986-10-01 DE DE8686113539T patent/DE3667139D1/de not_active Expired - Lifetime
- 1986-10-01 EP EP86113539A patent/EP0218190B1/en not_active Expired
-
1989
- 1989-11-30 GR GR89400263T patent/GR3000235T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
JPS62129296A (ja) | 1987-06-11 |
DE3667139D1 (de) | 1990-01-04 |
GR3000235T3 (en) | 1991-03-15 |
ES2011767B3 (es) | 1990-02-16 |
EP0218190B1 (en) | 1989-11-29 |
EP0218190A3 (en) | 1987-09-30 |
EP0218190A2 (en) | 1987-04-15 |
IT8522327A0 (it) | 1985-10-01 |
ATE48231T1 (de) | 1989-12-15 |
US4772463A (en) | 1988-09-20 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
BR9710822A (pt) | Composição baseada para tratamento pessoal. | |
DE3060877D1 (en) | Use of (meth)acrylic acid and maleic acid copolymers as incrustation inhibitors in detergents | |
MX171550B (es) | Composiciones para aplicacion topica en la piel, estables y de rapida ruptura | |
DK0839026T3 (da) | Micellære polyether-blokcopolymerkompositioner til målretning af biologiske midler | |
BR9815112A (pt) | Processo para a preparação de polìmeros sintéticos com teor de monÈmeros restantes muito baixo, produtos preparados a partir dos mesmos e seu emprego | |
ATE116857T1 (de) | Oligodesoxynukleotide als inhibitoren der replikation von retroviren und der expression von onkogenen. | |
TR200101805T2 (tr) | Siloksisilikat malzeme içeren kararlı hale getirilmiş şampuan. | |
ATE222505T1 (de) | Flüssige polymerzusammensetzung und verfahren zu ihrer verwendung | |
MX9404063A (es) | Amplificacion simultanea de objetivos multiples. | |
DK578685D0 (da) | Acrylatdispersion og dens anvendelse til fortykning af hydrogenperoxidpraeparater | |
IT1201474B (it) | Derivati macromolecolarizzati di cdp-colina,procedimento per la loro preparazione e composizioni farmaceutiche che li contengono | |
MX9304893A (es) | Articulos fotocromicos estables a la temperatura y protegidos de la luz solar. | |
FR2432542A1 (fr) | Acrylate azote reticule par un polyepoxyde utilisable comme composition de revetement | |
ATE486613T1 (de) | Mit nucleinsäure complexierte block-copolymere | |
FR2671088B1 (fr) | Nouveaux copolymeres a base de n-alkyl acrylamide, leur preparation et leur utilisation comme agents epaississants, notamment dans des compositions de shampooing. | |
FR2483932B1 (fr) | Nouvelles compositions polymere acrylique, procede pour leur obtention, et application notamment comme agents antitartres | |
DE59506963D1 (de) | Medizinischer haftkleber | |
AR009525A1 (es) | Composicion para tratamiento de cuero, procedimiento para su preparacion, y aplicacion de la misma. | |
ES2089402T3 (es) | Polimeros que contienen acido fosfinico y su utilizacion en la prevencion de la incrustacion y corrosion. | |
ES2030982T3 (es) | Dispersion acuosa de polimeros del tipo estireno-acrilico y su aplicacion para la obtencion de composiciones adhesivas resistentes al agua, adecuadas principalmente en el campo del embaldosado. | |
ES548737A0 (es) | Procedimiento para la preparacion de polimeros modificados abase de monomeros alfa-beta insaturados | |
ES2019088B3 (es) | Dispersion acuosa de un polimero de adicion, una composicion de recubrimiento basada en ella y un procedimiento para recubrir un sustrato con dicha composicion de recubrimiento. | |
SE9900941D0 (sv) | Novel retinoic acid derivatives and their use | |
ATE90198T1 (de) | Hautschutzmittel. | |
AR011392A1 (es) | Metodo y composicion para aumentar la productividad de las plantas |