[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

IT1271461B - ANTI-CD3 / ANTI-EGFR MONOCLONAL ANTI-BODY ANTIBODY, PROCESS FOR PRODUCTION AND ITS USE. - Google Patents

ANTI-CD3 / ANTI-EGFR MONOCLONAL ANTI-BODY ANTIBODY, PROCESS FOR PRODUCTION AND ITS USE.

Info

Publication number
IT1271461B
IT1271461B ITFI930246A ITFI930246A IT1271461B IT 1271461 B IT1271461 B IT 1271461B IT FI930246 A ITFI930246 A IT FI930246A IT FI930246 A ITFI930246 A IT FI930246A IT 1271461 B IT1271461 B IT 1271461B
Authority
IT
Italy
Prior art keywords
production
egfr monoclonal
body antibody
antibody
monoclonal anti
Prior art date
Application number
ITFI930246A
Other languages
Italian (it)
Inventor
Antonio Mele
Santis Rita De
Marsal Cristina Ferrer
Original Assignee
Menarini Ricerche Sud Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Menarini Ricerche Sud Spa filed Critical Menarini Ricerche Sud Spa
Priority to ITFI930246A priority Critical patent/IT1271461B/en
Publication of ITFI930246A0 publication Critical patent/ITFI930246A0/en
Priority to PCT/EP1994/003995 priority patent/WO1995016037A1/en
Priority to AU12417/95A priority patent/AU1241795A/en
Publication of ITFI930246A1 publication Critical patent/ITFI930246A1/en
Application granted granted Critical
Publication of IT1271461B publication Critical patent/IT1271461B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2809—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
ITFI930246A 1993-12-01 1993-12-01 ANTI-CD3 / ANTI-EGFR MONOCLONAL ANTI-BODY ANTIBODY, PROCESS FOR PRODUCTION AND ITS USE. IT1271461B (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
ITFI930246A IT1271461B (en) 1993-12-01 1993-12-01 ANTI-CD3 / ANTI-EGFR MONOCLONAL ANTI-BODY ANTIBODY, PROCESS FOR PRODUCTION AND ITS USE.
PCT/EP1994/003995 WO1995016037A1 (en) 1993-12-01 1994-12-01 Anti-egf-r/anti-cd3 bispecific monoclonal antibody, method for its production and its use
AU12417/95A AU1241795A (en) 1993-12-01 1994-12-01 Anti-egf-r/anti-cd3 bispecific monoclonal antibody, method for its production and its use

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITFI930246A IT1271461B (en) 1993-12-01 1993-12-01 ANTI-CD3 / ANTI-EGFR MONOCLONAL ANTI-BODY ANTIBODY, PROCESS FOR PRODUCTION AND ITS USE.

Publications (3)

Publication Number Publication Date
ITFI930246A0 ITFI930246A0 (en) 1993-12-01
ITFI930246A1 ITFI930246A1 (en) 1995-06-01
IT1271461B true IT1271461B (en) 1997-05-28

Family

ID=11350667

Family Applications (1)

Application Number Title Priority Date Filing Date
ITFI930246A IT1271461B (en) 1993-12-01 1993-12-01 ANTI-CD3 / ANTI-EGFR MONOCLONAL ANTI-BODY ANTIBODY, PROCESS FOR PRODUCTION AND ITS USE.

Country Status (3)

Country Link
AU (1) AU1241795A (en)
IT (1) IT1271461B (en)
WO (1) WO1995016037A1 (en)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6018031A (en) * 1989-10-20 2000-01-25 Trustees Of Dartmouth College Binding agents specific for IgA receptor
US6465253B1 (en) 1994-09-08 2002-10-15 Genvec, Inc. Vectors and methods for gene transfer to cells
US5846782A (en) * 1995-11-28 1998-12-08 Genvec, Inc. Targeting adenovirus with use of constrained peptide motifs
US5559099A (en) * 1994-09-08 1996-09-24 Genvec, Inc. Penton base protein and methods of using same
US5770442A (en) * 1995-02-21 1998-06-23 Cornell Research Foundation, Inc. Chimeric adenoviral fiber protein and methods of using same
US6127525A (en) * 1995-02-21 2000-10-03 Cornell Research Foundation, Inc. Chimeric adenoviral coat protein and methods of using same
US5922845A (en) * 1996-07-11 1999-07-13 Medarex, Inc. Therapeutic multispecific compounds comprised of anti-Fcα receptor antibodies
US20030017138A1 (en) 1998-07-08 2003-01-23 Menzo Havenga Chimeric adenoviruses
US6929946B1 (en) 1998-11-20 2005-08-16 Crucell Holland B.V. Gene delivery vectors provided with a tissue tropism for smooth muscle cells, and/or endothelial cells
US6913922B1 (en) 1999-05-18 2005-07-05 Crucell Holland B.V. Serotype of adenovirus and uses thereof
US6492169B1 (en) 1999-05-18 2002-12-10 Crucell Holland, B.V. Complementing cell lines
DE60138403D1 (en) 2000-09-26 2009-05-28 Crucell Holland Bv ADENOVIRAL VECTORS FOR THE TRANSFER OF GENES IN CELLS OF THE SKELETAL MUSCULATORY OR MYOBLAST
US7595378B2 (en) 2001-06-13 2009-09-29 Genmab A/S Human monoclonal antibodies to epidermal growth factor receptor (EGFR)
HUP0600225A3 (en) * 2001-06-13 2010-01-28 Genmab As Human monoclonal antibodies to epidermal growth factor receptor (egfr)
CA2477954C (en) 2002-04-25 2012-07-10 Crucell Holland B.V. Means and methods for the production of adenovirus vectors
JP3803790B2 (en) 2003-02-17 2006-08-02 株式会社東北テクノアーチ Novel diabody-type bispecific antibody
TWI320788B (en) 2005-05-25 2010-02-21 Hoffmann La Roche Method for the purification of antibodies
EP1940881B1 (en) * 2005-10-11 2016-11-30 Amgen Research (Munich) GmbH Compositions comprising cross-species-specific antibodies and uses thereof
WO2008119566A2 (en) * 2007-04-03 2008-10-09 Micromet Ag Cross-species-specific bispecific binders
CN101679509A (en) 2007-06-01 2010-03-24 弗·哈夫曼-拉罗切有限公司 immunoglobulin purification
CN101307109B (en) * 2008-06-04 2010-11-17 张传林 Mouse-anti-human T lymphocyte CD3 surface antigen monoclonal antibodies, method for preparing same and use
KR20110086184A (en) 2008-12-22 2011-07-27 에프. 호프만-라 로슈 아게 Immunoglobulin purification
ES2683268T3 (en) 2013-07-25 2018-09-25 Cytomx Therapeutics, Inc. Multispecific antibodies, multispecific activatable antibodies and methods for using them
SG11201609707WA (en) 2014-07-01 2017-01-27 Pfizer Bispecific heterodimeric diabodies and uses thereof
CN107108738A (en) 2014-07-25 2017-08-29 西托姆克斯治疗公司 Anti-cd 3 antibodies, it anti-cd 3 antibodies, polyspecific anti-cd 3 antibodies, polyspecific can be activated can activate anti-cd 3 antibodies and its application method
KR20200064096A (en) 2017-10-14 2020-06-05 싸이톰스 테라퓨틱스, 인크. Antibodies, activatable antibodies, bispecific antibodies and bispecific activatable antibodies and methods of using them
EP4225792A1 (en) 2020-10-08 2023-08-16 Affimed GmbH Trispecific binders
IL308154A (en) 2021-07-30 2023-12-01 Affimed Gmbh Duplexbodies

Also Published As

Publication number Publication date
AU1241795A (en) 1995-06-27
ITFI930246A1 (en) 1995-06-01
WO1995016037A1 (en) 1995-06-15
ITFI930246A0 (en) 1993-12-01

Similar Documents

Publication Publication Date Title
IT1271461B (en) ANTI-CD3 / ANTI-EGFR MONOCLONAL ANTI-BODY ANTIBODY, PROCESS FOR PRODUCTION AND ITS USE.
NO924279D0 (en) LYOPHILIZED, MONOCLONAL ANTIBODY PREPARATION
FI956112A (en) Monoclonal anti-V integrin antibody
EP0618929A4 (en) Bispecific antibody heterodimers.
DE68914244D1 (en) Monoclonal antibody.
CY2006001I2 (en) HUMANIZED HEREGULIN ANTIBODY
ATE248192T1 (en) HUMANIZED ANTIBODIES THAT BIND TO THE SAME ANTIGEN AS ANTIBODIES NR-LU-13 AND THEIR USE IN PRETARGETING PROCESSES
DE3854502D1 (en) AGAINST HIV-ANTIGENT SPECIFIC MONOCLONAL ANTIBODIES.
EP0741144A4 (en) Antiannexin-v monoclonal antibody, process for producing the same, and use therof
AU7203194A (en) Bispecific human monoclonal antibodies specific for human immunodeficiency virus
TR199501542A2 (en) Monoclonal antibody fragments with anti-immune activity.
DK557289A (en) MONOCLONAL, FUCOSYL CERAMID-RECOGNIZING ANTIBODY, ITS MANUFACTURING AND USE, AND HYBRIDOMA FOR THE MANUFACTURING
KR950700390A (en) Reinforced hydrocarbon, manufacturing method and use method (FORTIFIED HYDROCARBON AND PROCESS FOR MAKING AND USING THE SAME)
DE59608073D1 (en) ANTIBODIES AGAINST A FUSION POLYPEPTIDE HAVING A HISTIDINE PART
IT1184668B (en) LINFOKINA, ITS SPECIFIC MONOCLONAL ANTIBODY AND RELATED PRODUCTION PROCESS
EP0667395A4 (en) Monoclonal antibody, process for producing the same, and use thereof.
MX9202642A (en) MONOCLONAL ANTIBODIES AND ANTIGEN FOR HUMAN MELANOMA.
EP0640621A3 (en) Anti-thrombin monoclonal antibody.
NO894555D0 (en) MONOCLONAL ANTIBODY THAT SPECIFICALLY RECOGNIZES N-GLYCOLYL TYPE GM2, HYBRIDOM THAT PRODUCES ANTIBODY AND PROCEDURE FOR PRODUCING THE HYBRIDOM.
IT8821702A0 (en) NEW MONOCLONAL ANTIBODY.
EP0654532A4 (en) Antimucoglycoprotein monoclonal antibody.
ITMI911767A1 (en) POLYCLONAL ANTI-IRUDIN ANTIBODIES AND THEIR USE FOR THE IDENTIFICATION, LyIMMUNOPURIFICATION AND QUANTITATIVE DETERMINATION OFURIDIN.
DE69020315D1 (en) MONOCLONAL ANTIBODY AGAINST C-REACTIVE PROTEIN.
EP0538267A4 (en) Monoclonal anti-igm antibodies, their production and use, and hybridomas for producing the same
ZA986064B (en) Ancrod-specific monoclonal antibodies, antibody fragments, mixtures or derivatives thereof and their use.

Legal Events

Date Code Title Description
0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19961230