[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

IT1270008B - PURINIC AND 8-AZAPURINIC DERIVATIVES FOR THE THERAPEUTIC TREATMENT OF AIDS - Google Patents

PURINIC AND 8-AZAPURINIC DERIVATIVES FOR THE THERAPEUTIC TREATMENT OF AIDS

Info

Publication number
IT1270008B
IT1270008B ITMI941939A ITMI941939A IT1270008B IT 1270008 B IT1270008 B IT 1270008B IT MI941939 A ITMI941939 A IT MI941939A IT MI941939 A ITMI941939 A IT MI941939A IT 1270008 B IT1270008 B IT 1270008B
Authority
IT
Italy
Prior art keywords
derivatives
azapurinic
purinic
aids
therapeutic treatment
Prior art date
Application number
ITMI941939A
Other languages
Italian (it)
Inventor
Mario Grifantini
Palmarisa Franchetti
Loredana Cappellacci
Colla Paolo La
Anna Giulia Loi
Giovanna Piras
Original Assignee
Ist Superiore Sanita
Univ Cagliari
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ist Superiore Sanita, Univ Cagliari filed Critical Ist Superiore Sanita
Priority to ITMI941939A priority Critical patent/IT1270008B/en
Publication of ITMI941939A0 publication Critical patent/ITMI941939A0/en
Priority to PCT/EP1995/003791 priority patent/WO1996009307A1/en
Priority to AU37422/95A priority patent/AU3742295A/en
Publication of ITMI941939A1 publication Critical patent/ITMI941939A1/en
Application granted granted Critical
Publication of IT1270008B publication Critical patent/IT1270008B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • C07F9/65616—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system having three or more than three double bonds between ring members or between ring members and non-ring members, e.g. purine or analogs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La presente invenzione si riferisce a nuovi derivati purinici ed 8-azapurinici, al processo per la loro preparazione ed al loro uso nella terapia delle infezioni da virus HIV da soli o in associazione con AZT e/o ddI e/o ddC.The present invention relates to new purine and 8-azapurine derivatives, the process for their preparation and their use in the treatment of HIV virus infections either alone or in association with AZT and / or ddI and / or ddC.

ITMI941939A 1994-09-23 1994-09-23 PURINIC AND 8-AZAPURINIC DERIVATIVES FOR THE THERAPEUTIC TREATMENT OF AIDS IT1270008B (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
ITMI941939A IT1270008B (en) 1994-09-23 1994-09-23 PURINIC AND 8-AZAPURINIC DERIVATIVES FOR THE THERAPEUTIC TREATMENT OF AIDS
PCT/EP1995/003791 WO1996009307A1 (en) 1994-09-23 1995-09-25 Purine and 8-azapurine derivatives suitable to the therapeutic treatment of aids
AU37422/95A AU3742295A (en) 1994-09-23 1995-09-25 Purine and 8-azapurine derivatives suitable to the therapeutic treatment of aids

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI941939A IT1270008B (en) 1994-09-23 1994-09-23 PURINIC AND 8-AZAPURINIC DERIVATIVES FOR THE THERAPEUTIC TREATMENT OF AIDS

Publications (3)

Publication Number Publication Date
ITMI941939A0 ITMI941939A0 (en) 1994-09-23
ITMI941939A1 ITMI941939A1 (en) 1996-03-23
IT1270008B true IT1270008B (en) 1997-04-16

Family

ID=11369590

Family Applications (1)

Application Number Title Priority Date Filing Date
ITMI941939A IT1270008B (en) 1994-09-23 1994-09-23 PURINIC AND 8-AZAPURINIC DERIVATIVES FOR THE THERAPEUTIC TREATMENT OF AIDS

Country Status (3)

Country Link
AU (1) AU3742295A (en)
IT (1) IT1270008B (en)
WO (1) WO1996009307A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY141789A (en) 2001-01-19 2010-06-30 Lg Chem Investment Ltd Novel acyclic nucleoside phosphonate derivatives, salts thereof and process for the preparation of the same.
WO2006138264A2 (en) 2005-06-14 2006-12-28 Schering Corporation Aspartyl protease inhibitors
US9593137B2 (en) 2011-12-22 2017-03-14 Geron Corporation Guanine analogs as telomerase substrates and telomere length affectors

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU613592B2 (en) * 1986-11-18 1991-08-08 Institute Of Organic Chemistry And Biochemistry Of The Academy Of Sciences Of The Czech Republic Antiviral phosophonomethoxy-alkyene purine and pyrimide derivatives
DE69218968T2 (en) * 1991-10-11 1997-10-09 Inst Of Organic Chemistry And ANTIVIRAL ACYCLIC PHOSPHONOMETHOXYALKYL SUBSTITUTED, ALKENYL AND ALKYNYL PURINE AND PYRIMIDINE DERIVATIVES
US6057305A (en) * 1992-08-05 2000-05-02 Institute Of Organic Chemistry And Biochemistry Of The Academy Of Sciences Of The Czech Republic Antiretroviral enantiomeric nucleotide analogs

Also Published As

Publication number Publication date
AU3742295A (en) 1996-04-09
WO1996009307A1 (en) 1996-03-28
ITMI941939A1 (en) 1996-03-23
ITMI941939A0 (en) 1994-09-23

Similar Documents

Publication Publication Date Title
BR0108657A (en) Compound, process for the preparation and use thereof, and process for the preparation of (alpha) -ethyl-2-oxo-1-pyrrolidine acetamide or (r) -alpha-ethyl-2-oxo-1-pyrrolidine acetamide
CA2293470A1 (en) Benzimidazole derivatives
MD1224B2 (en) Application of nucleoside analogues with 1,3-oxathiolan for treatment of hepatitis B
CA2033044A1 (en) 6-substituted purine carbocyclic nucleosides
CA2081356A1 (en) Derivatives and analogues of 2-deoxy-2,3-didehydro-n- acetyl neuraminic acid and their use as antiviral agents
BR9813811A (en) "pharmaceutical compositions comprising micelles comprising lipophilic glucocorticosteroid and only a single surfactant"
TW226333B (en)
AR240251A1 (en) METHOD TO PREPARE A COMPOSITION FOR TREATMENT OF VIRAL INFECTIONS AND A METHOD TO SYNTHESIZE 3 'AZIDO 2', 3 'DIDEOXIURIDINA INTENDED FOR THE PREPARATION OF SUCH COMPOSITION.
CA2059263A1 (en) Composition comprising the (-) enantiomer of cis-4-amino-1-(2-hydromethyl-1,3-oxathiolan-5-yl)-(1h)-pyrimidine-2-one or an enriched composition thereof, and its uses as a pharmaceutical agent
PT82580B (en) Process for the preparation of 2 ', 3'-DIDESOXINUCLEOSIDOS AND OF PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM
TR200002773T2 (en) Smilagen and anzurogenin-D and their use for the treatment of Alzheimer's.
PL327061A1 (en) Treatment of hiv infection effects occured in the central nervous system by means o vx-478 preparation used solely or in combination wit azt or 3tc
CA2129995A1 (en) Piperidinyl thiacyclic derivatives
BG101118A (en) Therapeutical compounds
IT1282797B1 (en) PYRRYL-(INDOLYL)-ARIL-SULFONES AND RELATED PRODUCTION PROCESS AND USE IN THE THERAPY OF AIDS VIRUS INFECTIONS
ES2174273T3 (en) USE OF HEPARINE OR HEPARAN-SULFATE IN COMBINATION WITH QUITOSAN FOR THE PREVENTION OR TREATMENT OF INFECTIONS CAUSED BY VIRUS HERPES.
BR9809117A (en) Composition of delayed release gel, process of producing the same, pharmaceutical formulation, and processes of treatment of an indication, a disease, and inflammation with a composition of prolonged release
IT1305313B1 (en) 3,4 - DIHYDRO- 6- BENZYL-4-OXOPYRIMIDINE REPLACED AND RELATED PROCESS OF PRODUCTION AND USE IN THE THERAPY OF HIV-1 INFECTIONS.
CA2251132A1 (en) Use of phosphinyloxyalkyl and phosphonamidoalkyl derivatives of cyclopentane(ene) as therapeutic agents
EE03193B1 (en) (1-heteroazolyl-1-heterocyclyl) alkane derivatives, processes for their preparation and their use in the manufacture of protective agents for the nervous system
IT1270008B (en) PURINIC AND 8-AZAPURINIC DERIVATIVES FOR THE THERAPEUTIC TREATMENT OF AIDS
AU637999B2 (en) Use of 5'deoxy-5'methylthioadenosine, s-adenosylmethionine and their salts in the preparation of pharmaceutical compositions favouring hair growth in subjects suffering from baldness, and relative pharmaceutical compositions
BR9916043A (en) Compound, use of the same and its pharmaceutically acceptable salts, and pharmaceutical composition for the treatment of viral herpes infections in patients
NZ324118A (en) Furan-and thiophenecarbothioamide derivatives, their preparation and their use as inhibitors of the replication of hiv-1 and hiv-1 mutants
ITRM920408A0 (en) CULTURES OF DIFFERENTIATED CONJUNCTIVAL MUCOSA TISSUE, PROCEDURE FOR THEIR PREPARATION AND SUPPORTS FOR THEIR USE.

Legal Events

Date Code Title Description
0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19940729