IT1116654B - Metodo per la produzione di gona-4,9 10 dieni - Google Patents

Metodo per la produzione di gona-4,9 10 dieni

Info

Publication number: IT1116654B
Authority: IT; Italy
Prior art keywords: dieni; gona; production
Prior art date: 1976-06-14

Application number

IT49669/77A

Other languages

English (en)

Inventor

Ponsold Kurt

Hubner Michael

Oettel Michael

Original Assignee

Jenapharm Veb

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1976-06-14

Filing date

1977-06-01

Publication date

1986-02-10

1976-06-14 Priority claimed from DD7600193348A external-priority patent/DD132497A1/xx

1977-06-01 Application filed by Jenapharm Veb filed Critical Jenapharm Veb

1986-02-10 Application granted granted Critical

1986-02-10 Publication of IT1116654B publication Critical patent/IT1116654B/it

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0051—Estrane derivatives
- C07J1/0081—Substituted in position 17 alfa and 17 beta
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0044—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 with an estrane or gonane skeleton, including 18-substituted derivatives and derivatives where position 17-beta is substituted by a carbon atom not directly bonded to another carbon atom and not being part of an amide group
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0094—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 containing nitrile radicals, including thiocyanide radicals

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Toxicology (AREA)
Veterinary Medicine (AREA)
Endocrinology (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Engineering & Computer Science (AREA)
Diabetes (AREA)
Steroid Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Catalysts (AREA)
Epoxy Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

IT49669/77A 1976-06-14 1977-06-01 Metodo per la produzione di gona-4,9 10 dieni IT1116654B (it)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DD7600193348A DD132497A1 (de)	1976-06-14	1976-06-14	Verfahren zur herstellung von neuen gona-4,9(10)-dienen

Publications (1)

Publication Number	Publication Date
IT1116654B true IT1116654B (it)	1986-02-10

Family

ID=5504816

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IT49669/77A IT1116654B (it)	1976-06-14	1977-06-01	Metodo per la produzione di gona-4,9 10 dieni

Country Status (18)

Country	Link
US (1)	US4248790A (it)
JP (1)	JPS5312849A (it)
BE (1)	BE855617A (it)
BR (1)	BR7703832A (it)
CH (1)	CH635594A5 (it)
DE (1)	DE2718872A1 (it)
DK (1)	DK259477A (it)
ES (1)	ES461987A3 (it)
FI (1)	FI57113C (it)
FR (1)	FR2393008A1 (it)
GB (1)	GB1524917A (it)
HU (1)	HU177333B (it)
IT (1)	IT1116654B (it)
MX (1)	MX4685E (it)
NL (1)	NL187167C (it)
NO (2)	NO145244C (it)
SE (1)	SE426833B (it)
YU (1)	YU39804B (it)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
HU201091B (en)	1985-12-26	1990-09-28	Mitsubishi Chem Ind	Process for producing gonatriene derivatives and pharmaceutical compositions comprising same
JPS6322598A (ja) *	1986-07-14	1988-01-30	Mitsubishi Chem Ind Ltd	ゴナトリエン誘導体およびその製造法
JPS6372627A (ja) *	1986-09-17	1988-04-02	Mitsubishi Kasei Corp	子宮内膜症治療薬
JPH0780335B2 (ja) *	1989-11-20	1995-08-30	富士通株式会社	リボンカセット
PT654267E (pt) *	1993-11-19	2002-09-30	Jenapharm Gmbh	Carcinoestaticos para terapia hormonal contendo dienogest como componente eficaz
DK0780397T3 (da)	1995-12-22	1999-03-29	Jenapharm Gmbh	17alfa-cyanomethylestra-4,9-dien-derivater, fremgangsmåde til deres fremstilling og farmaceutiske præparater indeholdende d
US6479475B1 (en)	1996-07-26	2002-11-12	Wyeth	Oral contraceptive
US6451778B1 (en)	1996-07-26	2002-09-17	Wyeth	Oral contraceptive
US5888543A (en) *	1996-07-26	1999-03-30	American Home Products Corporation	Oral contraceptives
US5858405A (en) *	1996-07-26	1999-01-12	American Home Products Corporation	Oral contraceptive
HUP0501132A2 (en) *	2005-12-05	2007-06-28	Richter Gedeon Nyrt	17-alpha-cyanomethyl-17betha-hydroxyestra-4,9-diene-3-one of high purity and process for its production
US8617597B2 (en)	2006-07-06	2013-12-31	Bayer Intellectual Property Gmbh	Pharmaceutical composition containing a tetrahydrofolic acid
EP2256128B1 (en) *	2009-05-22	2011-12-07	HEYL Chemisch-Pharmazeutische Fabrik GmbH und Co. KG	Method for synthesis of dienogest from estrone-3-methylether
US20130041166A1 (en)	2010-04-20	2013-02-14	Lupin Limited	Process for the preparation of dienogest substantially free of impurities
CN112724191B (zh) *	2020-12-30	2022-11-15	上海汇伦医药股份有限公司	一种地诺孕素的精制方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3502699A (en) *	1962-05-15	1970-03-24	Herchel Smith	Novel delta4,9-3-ketosteroids and method for preparing same
DE1214223B (de) *	1962-11-22	1966-04-14	Roussel Uclaf	Verfahren zur Herstellung von Hydroxy-hydroxymethyl-steroiden
US3624110A (en) *	1964-08-03	1971-11-30	Herchel Smith	13-ethylgona-4,9-dienes
GB1130881A (en) *	1964-08-06	1968-10-16	Merck & Co Inc	Steroidal-í¸-dien-3-ones and derivatives thereof
FR2031807A5 (en) *	1969-02-07	1970-11-20	Jenapharm Veb	17a-subst estratrienes
US3931154A (en) *	1973-07-07	1976-01-06	Schering Aktiengesellschaft	Process for the preparation of steroid oxiranes
US4029648A (en) *	1976-01-15	1977-06-14	Veb Jenapharm	Process of making gona-1,3,5(10),9(11)-tetraenes

1977
- 1977-04-28 DE DE19772718872 patent/DE2718872A1/de active Granted
- 1977-06-01 IT IT49669/77A patent/IT1116654B/it active
- 1977-06-09 GB GB24086/77A patent/GB1524917A/en not_active Expired
- 1977-06-13 NO NO772054A patent/NO145244C/no unknown
- 1977-06-13 BE BE178379A patent/BE855617A/xx not_active IP Right Cessation
- 1977-06-13 DK DK259477A patent/DK259477A/da not_active Application Discontinuation
- 1977-06-13 BR BR7703832A patent/BR7703832A/pt unknown
- 1977-06-13 YU YU1465/77A patent/YU39804B/xx unknown
- 1977-06-13 SE SE7706835A patent/SE426833B/xx unknown
- 1977-06-13 NL NLAANVRAGE7706465,A patent/NL187167C/xx not_active IP Right Cessation
- 1977-06-13 CH CH724177A patent/CH635594A5/de not_active IP Right Cessation
- 1977-06-13 FR FR7718009A patent/FR2393008A1/fr active Granted
- 1977-06-14 MX MX775803U patent/MX4685E/es unknown
- 1977-06-14 HU HU77JE800A patent/HU177333B/hu unknown
- 1977-06-14 FI FI771865A patent/FI57113C/fi not_active IP Right Cessation
- 1977-06-14 JP JP7039777A patent/JPS5312849A/ja active Granted
- 1977-08-31 ES ES461987A patent/ES461987A3/es not_active Expired
1979
- 1979-02-13 US US06/011,951 patent/US4248790A/en not_active Expired - Lifetime
1981
- 1981-05-25 NO NO811764A patent/NO146574C/no unknown

Also Published As

Publication number	Publication date
NO145244B (no)	1981-11-02
FI771865A (it)	1977-12-15
NO772054L (no)	1977-12-15
HU177333B (en)	1981-09-28
NO145244C (no)	1982-02-10
NL187167B (nl)	1991-01-16
MX4685E (es)	1982-07-30
ES461987A3 (es)	1978-06-01
US4248790A (en)	1981-02-03
FR2393008B1 (it)	1982-05-07
DE2718872C2 (it)	1987-12-10
BR7703832A (pt)	1978-04-25
NO811764L (no)	1977-12-15
NO146574C (no)	1982-10-27
SE426833B (sv)	1983-02-14
FI57113B (fi)	1980-02-29
NL187167C (nl)	1991-06-17
JPS5312849A (en)	1978-02-04
BE855617A (fr)	1977-12-13
CH635594A5 (de)	1983-04-15
DE2718872A1 (de)	1977-12-22
JPS616838B2 (it)	1986-03-01
NL7706465A (nl)	1977-12-16
YU146577A (en)	1982-06-30
SE7706835L (sv)	1978-01-15
FI57113C (fi)	1980-06-10
DK259477A (da)	1977-12-15
YU39804B (en)	1985-04-30
GB1524917A (en)	1978-09-13
FR2393008A1 (fr)	1978-12-29
NO146574B (no)	1982-07-19

Publication	Publication Date	Title
IT7824577A0 (it)	1978-06-14	Metodo per la produzione di anticorpi.
IT1066280B (it)	1985-03-04	Procedimento per la produzione di tetraidro 1.4 ossazine n sostituite
IT1116654B (it)	1986-02-10	Metodo per la produzione di gona-4,9 10 dieni
IT1143706B (it)	1986-10-22	Metodo per la produzione di 2,4,6-tri-(3,5-diterziario butil-4-idrossibenzil) mesitilene
IT8023087A0 (it)	1980-06-26	Procedimento per la produzione di p-cloroalchilbenzene.
IT1084225B (it)	1985-05-25	Processo per la preparazione di eteri.
IT7830194A0 (it)	1978-11-24	Procedimento per la produzione di rifamicine.
IT7827797A0 (it)	1978-09-18	Processo per la produzione di 1,1,1,2-tetrafluoroetano.
SE428017B (sv)	1983-05-30	Forfarande for framstellning av 2,6 - metano - 2h-l- bensoxocinderivat
IT1102597B (it)	1985-10-07	Procedimento per la produzione di 2,3-dimetil-pentanale
IT1145435B (it)	1986-11-05	Procedimento per la produzione di 2,3-dimetilbutene-2
IT1126736B (it)	1986-05-21	Procedimento per la produzione di 1,1-difluoroetilene
IT8122146A0 (it)	1981-06-05	Procedimento per la produzione di mercapto-2-etanolo-1.
IT1143595B (it)	1986-10-22	Procedimento per la produzione di 2,3-cicloalchenopiridine
IT1079470B (it)	1985-05-13	Procedimento per la produzione di 1,2-dicloalcandioni
IT1114767B (it)	1986-01-27	Processo per la preparazione di 2,5-diosso-1,2-ossa-fosfolani
IT1091568B (it)	1985-07-06	Procedimento migliorato per la produzione di 5-nitroso-2,4,6-triammino-porimidina
IT1074841B (it)	1985-04-20	Processo per la preparazione di perfluoro-4-osso-2,5-dimetil-2-fluorocarbonil-1,3-diossolano.
IT1105154B (it)	1985-10-28	Procedimento per la produzione di 2,4-diosso-ossazolidine
IT7829095A0 (it)	1978-10-25	Procedimento per la produzione di tiolcarbamati.
PL202246A1 (pl)	1978-07-31	Sposob wytwarzania 1,1-dwuchlorowco-4-metylopentadienu-1,3
PL200936A1 (pl)	1978-05-22	Sposob wytwarzania kwasu 2,3-dwuchloro-4-/2-tenoilo/-fenoksyoctowego
IT1117280B (it)	1986-02-17	Procedimento per la polibromurazione di bisfenossialcani
PL200937A1 (pl)	1978-05-22	Sposob wytwarzania kwasu 2,3-dwuchloro-4-/2-tenoilo/-fenoksyoctowego
PL200935A1 (pl)	1978-05-22	Sposob wytwarzania kwasu 2,3-dwuchloro-4-/2-tenoilo/fenoksyoctowego

Legal Events

Date	Code	Title	Description
1999-10-27	TA	Fee payment date (situation as of event date), data collected since 19931001	Effective date: 19951228