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IT1077635B - Vasodilator aminoalkoxy condensed pyranone(s) - also having hypotensive, anti-ischaemic and antitussive activity - Google Patents

Vasodilator aminoalkoxy condensed pyranone(s) - also having hypotensive, anti-ischaemic and antitussive activity

Info

Publication number
IT1077635B
IT1077635B IT2030977A IT2030977A IT1077635B IT 1077635 B IT1077635 B IT 1077635B IT 2030977 A IT2030977 A IT 2030977A IT 2030977 A IT2030977 A IT 2030977A IT 1077635 B IT1077635 B IT 1077635B
Authority
IT
Italy
Prior art keywords
alkyl
condensed
pyranone
aminoalkoxy
ischaemic
Prior art date
Application number
IT2030977A
Other languages
Italian (it)
Original Assignee
Lipha
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR7605234A external-priority patent/FR2368952A1/en
Priority claimed from FR7701267A external-priority patent/FR2377394A2/en
Application filed by Lipha filed Critical Lipha
Application granted granted Critical
Publication of IT1077635B publication Critical patent/IT1077635B/en

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Pyranones of formula (I) and their acid-addition salts are new (where n is 0 or 1; n' is 0 or 1; R is alkyl, benzyl or phenyll opt. substd. by one or more halo, or by an alkoxy group; R' is H, OH, alkyl, 3,4,5-trialkoxybenzoyloxy; or R1 and R2 and the attached N-atom may form a saturated ring when n is 1 and n' is 0; R2 is alkyl; or R2 and R3 with the attached N atom form a heterocyclic ring, R3 is H, alkyl; X is a simple or condensed ring forming with the adjacent pyronic ring benzene, cyclohexene, cycloheptene, cycloctaene, cyclododecaene, naphthalene, dihydronaphthalene, 2-phenylindene and diphenyl; R4 is H, halo, OH, alkyl, alkoxy, morpholinoalkoxy and aryl; R5 is OH, alkyl, alkoxy and morpholinoalkoxy; R6, R7 and R8 are H or alkyl). A typical cpd., 4-(3-morpholino-2-hydroxypropoxy)-3-phenyl-5,6,7,8-tetrahydrocoum- arin was prepd. in 77% yield.
IT2030977A 1976-02-25 1977-02-15 Vasodilator aminoalkoxy condensed pyranone(s) - also having hypotensive, anti-ischaemic and antitussive activity IT1077635B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR7605234A FR2368952A1 (en) 1976-02-25 1976-02-25 NEW AMINOALCOXY-4 (2 H) PYRANONE-2,3 SUBSTITUTES-5,6 CONDENSES
FR7701267A FR2377394A2 (en) 1977-01-18 1977-01-18 Vasodilator aminoalkoxy condensed pyranone(s) - also having hypotensive, anti-ischaemic and antitussive activity

Publications (1)

Publication Number Publication Date
IT1077635B true IT1077635B (en) 1985-05-04

Family

ID=26219317

Family Applications (1)

Application Number Title Priority Date Filing Date
IT2030977A IT1077635B (en) 1976-02-25 1977-02-15 Vasodilator aminoalkoxy condensed pyranone(s) - also having hypotensive, anti-ischaemic and antitussive activity

Country Status (1)

Country Link
IT (1) IT1077635B (en)

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