IS469B6 - Aðferð til að framleiða ný fúkalyf sem nefnast demethyltetracyclin. - Google Patents
Aðferð til að framleiða ný fúkalyf sem nefnast demethyltetracyclin.Info
- Publication number
- IS469B6 IS469B6 IS986A IS986A IS469B6 IS 469 B6 IS469 B6 IS 469B6 IS 986 A IS986 A IS 986A IS 986 A IS986 A IS 986A IS 469 B6 IS469 B6 IS 469B6
- Authority
- IS
- Iceland
- Prior art keywords
- demethyltetracycline
- producing new
- new antibiotics
- antibiotics called
- called
- Prior art date
Links
- RMVMLZHPWMTQGK-SOUFLCLCSA-N (4s,4as,5as,6s,12ar)-4-(dimethylamino)-1,6,10,11,12a-pentahydroxy-3,12-dioxo-4a,5,5a,6-tetrahydro-4h-tetracene-2-carboxamide Chemical compound C1([C@H]2O)=CC=CC(O)=C1C(O)=C1[C@@H]2C[C@H]2[C@H](N(C)C)C(=O)C(C(N)=O)=C(O)[C@@]2(O)C1=O RMVMLZHPWMTQGK-SOUFLCLCSA-N 0.000 title 1
- 239000003242 anti bacterial agent Substances 0.000 title 1
- 229940088710 antibiotic agent Drugs 0.000 title 1
- JCSGAUKCDAVARS-UHFFFAOYSA-N demethyltetracycline Natural products CN(C1C(=C(C(C2(C(=C3C(C4=C(C=CC=C4C(C3CC12)O)O)=O)O)O)=O)C(=O)N)O)C JCSGAUKCDAVARS-UHFFFAOYSA-N 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P29/00—Preparation of compounds containing a naphthacene ring system, e.g. tetracycline
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/886—Streptomyces
- Y10S435/889—Streptomyces aureofaciens
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US587518A US2878289A (en) | 1956-05-28 | 1956-05-28 | 6-demethyltetracyclines and methods for preparing the same |
Publications (2)
Publication Number | Publication Date |
---|---|
IS986A7 IS986A7 (is) | 1957-11-29 |
IS469B6 true IS469B6 (is) | 1961-12-06 |
Family
ID=24350126
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IS986A IS469B6 (is) | 1956-05-28 | 1957-05-20 | Aðferð til að framleiða ný fúkalyf sem nefnast demethyltetracyclin. |
Country Status (5)
Country | Link |
---|---|
US (1) | US2878289A (is) |
CH (1) | CH365484A (is) |
DK (1) | DK104507C (is) |
ES (1) | ES235737A1 (is) |
IS (1) | IS469B6 (is) |
Families Citing this family (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3105016A (en) * | 1956-04-25 | 1963-09-24 | American Cyanamid Co | Process of producing bromo-tetracycline |
US2996499A (en) * | 1958-06-20 | 1961-08-15 | American Cyanamid Co | Cosynthetic factor-1, and its production |
US3047626A (en) * | 1959-09-24 | 1962-07-31 | Pfizer & Co C | 4-desdimethylamino-6-deoxy-tetracycline derivatives |
US3023239A (en) * | 1959-12-09 | 1962-02-27 | American Cyanamid Co | Recrystallization of demethylchlortetracycline |
US3019172A (en) * | 1960-03-14 | 1962-01-30 | American Cyanamid Co | Production of 7-chloro-6-demethyltetracycline |
US3070514A (en) * | 1960-05-04 | 1962-12-25 | Lepetit Spa | Process for the manufacture of 6-demethyltetracycline |
FR1430859A (is) * | 1960-05-23 | 1966-05-25 | ||
US3159537A (en) * | 1960-12-20 | 1964-12-01 | American Cyanamid Co | Potentiation of tetracycline by phosphinic acid |
US3028311A (en) * | 1960-08-05 | 1962-04-03 | Olin Mathieson | Process for preparing 6-demethyltetracyclines |
US3172822A (en) * | 1960-10-31 | 1965-03-09 | Process for preparing g-demethyl- tetracyclines | |
US3166474A (en) * | 1961-05-26 | 1965-01-19 | American Cyanamid Co | Stable aqueous propylene glycol solutions of aluminum gluconate complexes of certain tetracycline antibiotics |
US3335055A (en) * | 1961-08-30 | 1967-08-08 | American Cyanamid Co | More stable and more soluble tetracycline compositions suitable for parenteral use and method of preparing same |
US3069326A (en) * | 1961-10-31 | 1962-12-18 | American Cyanamid Co | Method of preparing 6-amino-5-hydroxy-1, 3-cyclohexadiene-1-carboxylic acid |
US3160570A (en) * | 1961-12-20 | 1964-12-08 | Merck & Co Inc | Method for producing 6-demethylchlortetracycline |
US3155586A (en) * | 1963-01-23 | 1964-11-03 | American Cyanamid Co | Stable liquid preparations of 6-demethyltetracyclines |
US3155587A (en) * | 1963-01-23 | 1964-11-03 | American Cyanamid Co | Stable liquid preparations of 7-chlorotetracycline |
FR2607M (fr) * | 1963-01-30 | 1964-06-22 | Soc Ind Fab Antibiotiques Sifa | Nouveau dérivé de la tétracycline. |
US3364260A (en) * | 1963-05-06 | 1968-01-16 | Squibb & Sons Inc | 4n-demethyl-4n-ethyl tetracyclines |
US3434844A (en) * | 1964-01-21 | 1969-03-25 | American Cyanamid Co | Stabilization of animal and poultry feeds containing a tetracycline antibiotic |
US3427166A (en) * | 1964-01-21 | 1969-02-11 | American Cyanamid Co | Stabilization of animal and poultry feeds containing a tetracycline antibiotic |
US3639214A (en) * | 1964-06-04 | 1972-02-01 | Upjohn Co | Production of 6-demethyltetracycline |
US3298927A (en) * | 1964-11-09 | 1967-01-17 | Olin Mathieson | Process for preparing 6-demethyltetracyclines using ethionine sulfoxide |
US3446841A (en) * | 1966-04-22 | 1969-05-27 | American Cyanamid Co | Isolation of 5-hydroxy-7-chlortetracycline |
US3607311A (en) * | 1968-02-16 | 1971-09-21 | Gerhard Julius Hass | Obtulinum exotoxin inhibited foods |
US3795707A (en) * | 1970-12-28 | 1974-03-05 | Rachelle Labor Italia Spa | Manufacture of alpha-6-deoxytetracyclines |
US4200630A (en) * | 1977-12-15 | 1980-04-29 | University Of Pennsylvania | Inhibition of ADH-stimulated osmotic water flow and aldosterone-stimulated sodium transport |
US5494903A (en) | 1991-10-04 | 1996-02-27 | American Cyanamid Company | 7-substituted-9-substituted amino-6-demethyl-6-deoxytetracyclines |
USRE40183E1 (en) | 1991-10-04 | 2008-03-25 | Wyeth Holdings Corporation | 7-Substituted-9-substituted amino-6-demethyl-6-deoxytetracyclines |
EP1069112A4 (en) * | 1998-02-13 | 2001-04-18 | Kureha Chemical Ind Co Ltd | N- (PHENYLSULFONYL) PICOLINAMIDE DERIVATIVES, METHOD FOR THEIR PREPARATION AND HERBICIDES |
US20020077276A1 (en) * | 1999-04-27 | 2002-06-20 | Fredeking Terry M. | Compositions and methods for treating hemorrhagic virus infections and other disorders |
PT108978B (pt) | 2015-11-24 | 2020-03-09 | Hovione Farm S A | Sais de tetraciclinas |
CN111100900A (zh) * | 2019-12-19 | 2020-05-05 | 河北圣雪大成制药有限责任公司 | 一种发酵法制备去甲基四环素的方法 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2482055A (en) * | 1948-02-11 | 1949-09-13 | American Cyanamid Co | Aureomycin and preparation of same |
BE487301A (is) * | 1948-02-11 | |||
BE530983A (is) * | 1953-09-28 | |||
US2699054A (en) * | 1953-10-09 | 1955-01-11 | Lloyd H Conover | Tetracycline |
BE533886A (is) * | 1953-12-04 | |||
US2712517A (en) * | 1954-03-03 | 1955-07-05 | Bristol Lab Inc | Production of tetracycline and substituted tetracyclines |
-
1956
- 1956-05-23 CH CH501062A patent/CH365484A/fr unknown
- 1956-05-28 US US587518A patent/US2878289A/en not_active Expired - Lifetime
-
1957
- 1957-05-20 IS IS986A patent/IS469B6/is unknown
- 1957-05-27 ES ES0235737A patent/ES235737A1/es not_active Expired
- 1957-05-27 DK DK185757AA patent/DK104507C/da active
Also Published As
Publication number | Publication date |
---|---|
US2878289A (en) | 1959-03-17 |
IS986A7 (is) | 1957-11-29 |
ES235737A1 (es) | 1957-12-01 |
DK104507C (da) | 1966-05-31 |
CH365484A (fr) | 1962-11-15 |
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