IN2014DN09450A - - Google Patents
Info
- Publication number
- IN2014DN09450A IN2014DN09450A IN9450DEN2014A IN2014DN09450A IN 2014DN09450 A IN2014DN09450 A IN 2014DN09450A IN 9450DEN2014 A IN9450DEN2014 A IN 9450DEN2014A IN 2014DN09450 A IN2014DN09450 A IN 2014DN09450A
- Authority
- IN
- India
- Prior art keywords
- rivaroxaban
- intermediates
- preparation
- present
- provides processes
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN9450DEN2014 IN2014DN09450A (tr) | 2012-04-16 | 2013-04-16 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN1174DE2012 | 2012-04-16 | ||
| IN9450DEN2014 IN2014DN09450A (tr) | 2012-04-16 | 2013-04-16 | |
| PCT/IB2013/053025 WO2013156936A1 (en) | 2012-04-16 | 2013-04-16 | Process for the preparation of rivaroxaban and intermediates thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2014DN09450A true IN2014DN09450A (tr) | 2015-07-17 |
Family
ID=48539327
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN9450DEN2014 IN2014DN09450A (tr) | 2012-04-16 | 2013-04-16 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20150299160A1 (tr) |
| EP (1) | EP2838897A1 (tr) |
| AU (1) | AU2013250801A1 (tr) |
| IN (1) | IN2014DN09450A (tr) |
| SG (1) | SG11201406623PA (tr) |
| WO (1) | WO2013156936A1 (tr) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103819468A (zh) * | 2013-12-05 | 2014-05-28 | 浙江天宇药业股份有限公司 | 一种利伐沙班及其中间体的合成方法 |
| IN2014MU00072A (tr) | 2014-01-08 | 2015-08-21 | Wockhardt Ltd | |
| CN104478820B (zh) * | 2014-12-22 | 2016-08-31 | 杭州瀚康生物医药科技有限公司 | 一种利伐沙班中间体的制备方法 |
| CN104910141B (zh) * | 2015-05-12 | 2018-11-02 | 浙江天顺生物科技有限公司 | 一种利伐沙班中间体5-氯-n-(2-环氧乙烷基甲基)-2-噻吩甲酰胺的制备方法 |
| CN104788444B (zh) * | 2015-05-12 | 2018-11-06 | 浙江天顺生物科技有限公司 | 利伐沙班的制备方法 |
| CN104817550B (zh) * | 2015-05-26 | 2017-06-16 | 山东铂源药业有限公司 | 一种利伐沙班的制备方法 |
| CN108707080B (zh) * | 2018-06-20 | 2022-01-25 | 上海圣赢生物科技有限公司 | 一种利奈唑胺及其中间体的环保合成方法 |
| CN109400577B (zh) * | 2019-01-07 | 2021-01-19 | 石药集团中奇制药技术（石家庄）有限公司 | 利伐沙班有关化合物及其制备方法和用途 |
| CN112110910B (zh) * | 2019-06-19 | 2024-03-19 | 上海特化医药科技有限公司 | 制备利伐沙班中间体的方法及由其制备利伐沙班的方法 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100387581C (zh) | 1997-11-07 | 2008-05-14 | 法玛西雅厄普约翰美国公司 | 制备唑烷酮的方法 |
| DE19962924A1 (de) | 1999-12-24 | 2001-07-05 | Bayer Ag | Substituierte Oxazolidinone und ihre Verwendung |
| DE10300111A1 (de) | 2003-01-07 | 2004-07-15 | Bayer Healthcare Ag | Verfahren zur Herstellung von 5-Chlor-N-({(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)-phenyl]-1,3-oxazolidin-5-yl}-methyl)-2-thiophencarboxamid |
| DE10322469A1 (de) | 2003-05-19 | 2004-12-16 | Bayer Healthcare Ag | Heterocyclische Verbindungen |
| DE102006051625A1 (de) | 2006-11-02 | 2008-05-08 | Bayer Materialscience Ag | Kombinationstherapie substituierter Oxazolidinone |
| DE102007028320A1 (de) * | 2007-06-20 | 2008-12-24 | Bayer Healthcare Ag | Substituierte Oxazolidinone und ihre Verwendung |
| DE102007032347A1 (de) | 2007-07-11 | 2009-01-15 | Bayer Healthcare Ag | Aminoacyl-Prodrugs |
| DE102007032345A1 (de) * | 2007-07-11 | 2009-01-15 | Bayer Healthcare Ag | Aminoacyl-Prodrugs |
| EP2354128A1 (en) | 2010-02-10 | 2011-08-10 | Sandoz Ag | Method for the preparation of rivaroxaban |
| CN102584738B (zh) | 2011-01-07 | 2015-04-29 | 浙江九洲药业股份有限公司 | 一种合成利伐沙班中间体的工艺 |
| WO2013046211A1 (en) * | 2011-09-27 | 2013-04-04 | Symed Labs Limited | Processes for the preparation of 5-chloro-n-({(5s)-2-oxo-3-[4-(3-oxo-4-morpholinyl) phenyl]-1,3-oxazolidin-5-yl}methyl)-2-thiophene-carboxamide and intermediates thereof |
-
2013
- 2013-04-16 EP EP13726292.9A patent/EP2838897A1/en not_active Withdrawn
- 2013-04-16 WO PCT/IB2013/053025 patent/WO2013156936A1/en active Application Filing
- 2013-04-16 US US14/394,547 patent/US20150299160A1/en not_active Abandoned
- 2013-04-16 SG SG11201406623PA patent/SG11201406623PA/en unknown
- 2013-04-16 AU AU2013250801A patent/AU2013250801A1/en not_active Abandoned
- 2013-04-16 IN IN9450DEN2014 patent/IN2014DN09450A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP2838897A1 (en) | 2015-02-25 |
| SG11201406623PA (en) | 2014-11-27 |
| WO2013156936A1 (en) | 2013-10-24 |
| AU2013250801A1 (en) | 2014-11-06 |
| US20150299160A1 (en) | 2015-10-22 |
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