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IN2014CN04294A - - Google Patents

Info

Publication number
IN2014CN04294A
IN2014CN04294A IN4294CHN2014A IN2014CN04294A IN 2014CN04294 A IN2014CN04294 A IN 2014CN04294A IN 4294CHN2014 A IN4294CHN2014 A IN 4294CHN2014A IN 2014CN04294 A IN2014CN04294 A IN 2014CN04294A
Authority
IN
India
Prior art keywords
void
cover member
biological sample
substrate
chamber
Prior art date
Application number
Inventor
Mark Brian Dockrill
Anthony Favaloro
Kenneth Heng Chong NG
Martin Limon
Peter Toogood
Stephen John Bagnato
Original Assignee
Leica Biosystems Melbourne Pty
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leica Biosystems Melbourne Pty filed Critical Leica Biosystems Melbourne Pty
Publication of IN2014CN04294A publication Critical patent/IN2014CN04294A/en

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • G01N1/31—Apparatus therefor
    • G01N1/312—Apparatus therefor for samples mounted on planar substrates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02—Adapting objects or devices to another
    • B01L2200/026—Fluid interfacing between devices or objects, e.g. connectors, inlet details
    • B01L2200/027—Fluid interfacing between devices or objects, e.g. connectors, inlet details for microfluidic devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0689—Sealing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0822—Slides
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0848—Specific forms of parts of containers
    • B01L2300/0851—Bottom walls
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0877—Flow chambers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/18—Means for temperature control
    • B01L2300/1805—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
    • B01L2300/1822—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks using Peltier elements
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/18—Means for temperature control
    • B01L2300/1805—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
    • B01L2300/1827—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks using resistive heater
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/18—Means for temperature control
    • B01L2300/1861—Means for temperature control using radiation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/18—Means for temperature control
    • B01L2300/1861—Means for temperature control using radiation
    • B01L2300/1866—Microwaves
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00—Heating or cooling apparatus; Heat insulating devices
    • B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L9/00—Supporting devices; Holding devices
    • B01L9/52—Supports specially adapted for flat sample carriers, e.g. for plates, slides, chips
    • B01L9/527—Supports specially adapted for flat sample carriers, e.g. for plates, slides, chips for microfluidic devices, e.g. used for lab-on-a-chip
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Clinical Laboratory Science (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

A cover member for a substrate supporting a biological sample comprises first and second opposing ends first and second opposing surfaces a void in the second surface which when juxtaposed with a substrate forms a chamber and a fluid inlet toward the first end and in fluid communication with the void. The void is bounded by void walls having one or more contoured regions for enhancing fluid movement within the chamber. A treatment module for a biological sample comprises the cover member a support surface for a substrate bearing the biological sample and clamp means operable to releasably retain the cover member in juxtaposition with the substrate for an incubation period. A method for incubating the biological sample with one or more reagents uses the cover member.
IN4294CHN2014 2011-11-16 2012-11-15 IN2014CN04294A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161560543P 2011-11-16 2011-11-16
PCT/AU2012/001407 WO2013071352A1 (en) 2011-11-16 2012-11-15 Cover member, method and treatment module for treating a biological sample on a substrate

Publications (1)

Publication Number Publication Date
IN2014CN04294A true IN2014CN04294A (en) 2015-09-04

Family

ID=48428835

Family Applications (1)

Application Number Title Priority Date Filing Date
IN4294CHN2014 IN2014CN04294A (en) 2011-11-16 2012-11-15

Country Status (9)

Country Link
US (3) US10549271B2 (en)
EP (1) EP2780721B1 (en)
JP (2) JP2014533823A (en)
CN (1) CN104094122B (en)
AU (1) AU2012339616B2 (en)
BR (1) BR112014011935B1 (en)
CA (1) CA2855511C (en)
IN (1) IN2014CN04294A (en)
WO (1) WO2013071352A1 (en)

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EP2914950B1 (en) * 2012-11-01 2023-01-04 Leica Biosystems Melbourne Pty Ltd An automated slide treatment apparatus
US10502666B2 (en) 2013-02-06 2019-12-10 Alentic Microscience Inc. Sample processing improvements for quantitative microscopy
JP2016531282A (en) 2013-06-26 2016-10-06 アレンティック マイクロサイエンス インコーポレイテッド Improved sample handling for microscopy
US10876937B2 (en) * 2013-10-04 2020-12-29 Biogenex Laboratories, Inc. Assembly for forming microchamber for inverted substrate
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US9958362B1 (en) * 2015-10-02 2018-05-01 The Florida State University Research Foundation, Inc. Microscope sample preparation device
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CN108152109B (en) * 2017-12-14 2021-02-09 深圳达盟生物科技有限公司 Slide glass cover body and method for cleaning tissue section by using same
CN108387428A (en) * 2018-02-26 2018-08-10 深圳安诺康生物医疗有限公司 A kind of colouring method of pathological section
US11719712B2 (en) * 2018-07-10 2023-08-08 Nanocytomics, LLC Automated sample deposition and staining systems and associated methods
KR102246609B1 (en) * 2018-08-01 2021-04-30 주식회사 미코바이오메드 Device for amplifying nucleic acid comprisng a plurality of heating blocks
KR20210104648A (en) * 2018-12-20 2021-08-25 라이카 바이오시스템즈 멜버른 피티와이 엘티디 slide output module
CN112771381A (en) * 2018-12-20 2021-05-07 莱卡生物系统墨尔本私人有限公司 Bulk fluid cleaning module
WO2020154248A1 (en) * 2019-01-21 2020-07-30 Forward Biotech, Inc. Liquid evaluation
CN109900542A (en) * 2019-03-15 2019-06-18 深圳市金准生物医学工程有限公司 The cavity device for the self-closed that test card incubates
EP3825004A1 (en) * 2019-11-22 2021-05-26 Koninklijke Philips N.V. New multi-functional fluidic device for clamping biopsies
CN115397558A (en) * 2020-04-24 2022-11-25 株式会社百奥尼 Trackable precision sample injection device for multi-well plate
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Also Published As

Publication number Publication date
CN104094122B (en) 2017-03-22
JP2018021932A (en) 2018-02-08
AU2012339616B2 (en) 2016-04-28
EP2780721B1 (en) 2017-08-16
EP2780721A4 (en) 2015-07-01
BR112014011935B1 (en) 2020-11-03
US11420200B2 (en) 2022-08-23
US20200188904A1 (en) 2020-06-18
US10549271B2 (en) 2020-02-04
CA2855511A1 (en) 2013-05-23
US20230077728A1 (en) 2023-03-16
US20140315256A1 (en) 2014-10-23
JP6633586B2 (en) 2020-01-22
WO2013071352A1 (en) 2013-05-23
CA2855511C (en) 2021-03-09
EP2780721A1 (en) 2014-09-24
AU2012339616A1 (en) 2014-06-12
CN104094122A (en) 2014-10-08
BR112014011935A2 (en) 2017-05-30
JP2014533823A (en) 2014-12-15

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