IN2012DN01292A - - Google Patents
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- Publication number
- IN2012DN01292A IN2012DN01292A IN1292DEN2012A IN2012DN01292A IN 2012DN01292 A IN2012DN01292 A IN 2012DN01292A IN 1292DEN2012 A IN1292DEN2012 A IN 1292DEN2012A IN 2012DN01292 A IN2012DN01292 A IN 2012DN01292A
- Authority
- IN
- India
- Prior art keywords
- therapy
- preparing
- processes
- compound
- formula
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Anesthesiology (AREA)
- Addiction (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US23743509P | 2009-08-27 | 2009-08-27 | |
PCT/EP2010/062420 WO2011023733A1 (en) | 2009-08-27 | 2010-08-25 | Anhydrate forms of a pyridine derivative |
Publications (1)
Publication Number | Publication Date |
---|---|
IN2012DN01292A true IN2012DN01292A (ar) | 2015-06-05 |
Family
ID=42790943
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IN1292DEN2012 IN2012DN01292A (ar) | 2009-08-27 | 2010-08-25 |
Country Status (18)
Country | Link |
---|---|
US (1) | US8796269B2 (ar) |
EP (1) | EP2470545B1 (ar) |
JP (3) | JP2013503134A (ar) |
KR (1) | KR20120056258A (ar) |
CN (1) | CN102639536B (ar) |
AU (1) | AU2010288502B2 (ar) |
BR (1) | BR112012003435A2 (ar) |
CA (1) | CA2772168C (ar) |
DK (1) | DK2470545T3 (ar) |
EA (1) | EA021411B1 (ar) |
ES (1) | ES2440938T3 (ar) |
IL (1) | IL217922A (ar) |
IN (1) | IN2012DN01292A (ar) |
MX (1) | MX2012002369A (ar) |
PL (1) | PL2470545T3 (ar) |
SG (1) | SG178231A1 (ar) |
WO (1) | WO2011023733A1 (ar) |
ZA (1) | ZA201200812B (ar) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8796269B2 (en) * | 2009-08-27 | 2014-08-05 | Nerre Therapeutics Limited | Crystalline 2-(3,5-Bis(trifluoromethyl)phenyl)-N-(4-(4-fluoro-2-methylphenyl)-6-((7S,9aS)-7-(hydroxymethyl)hexahydropyrazino[2,1-c][1,4]oxazin-8(1H)-yl)pyridin-3-yl)-N,2-dimethyl-propanamide of the formula (I), their use in therapy, and process for the preparation of the same |
ES2879375T3 (es) | 2014-06-25 | 2021-11-22 | Univ Emory | Procedimientos de manejo del miedo condicionado con antagonistas del receptor de neuroquinina |
PT3297631T (pt) * | 2015-05-18 | 2019-10-10 | Nerre Therapeutics Ltd | Receptor nk-1/nk-3 antagonista para o tratamento de afrontamentos |
CN110114361B (zh) * | 2016-12-15 | 2022-04-12 | 葛兰素史密斯克莱知识产权发展有限公司 | Nrf2化合物 |
LT3765024T (lt) * | 2018-03-14 | 2024-02-26 | KaNDy Therapeutics Limited | Nauja farmacinė vaisto forma, apimanti dvigubo nk-1/nk-3 receptoriaus antagonistus |
WO2021030335A1 (en) * | 2019-08-12 | 2021-02-18 | Millendo Therapeutics, Inc. | A stereoisomerically pure nk-3 receptor antagonist and crystalline forms thereof |
US20230002322A1 (en) | 2019-11-15 | 2023-01-05 | KaNDy Therapeutics Limited | New chemical process for making 6-chloro-4-(4-fluoro-2-methylphenyl)pyridin-3-amine a key intermediate of nt-814 |
EP4431512A1 (en) | 2023-03-16 | 2024-09-18 | Bayer Consumer Care AG | Novel dual nk-1/nk-3 receptor antagonists |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK1035115T3 (da) * | 1999-02-24 | 2005-01-24 | Hoffmann La Roche | 4-phenylpyridinderivater og anvendelse deraf som NK-1-receptorantagonister |
GB0203022D0 (en) * | 2002-02-08 | 2002-03-27 | Glaxo Group Ltd | Chemical compounds |
ES2290666T3 (es) * | 2003-01-31 | 2008-02-16 | F. Hoffmann-La Roche Ag | Nueva modificacion cristalina de la 2-(3,5-bis-trifluormetil-fenil)-n-(6-(1,1-dioxo-1landa6-tiomorfolin-4-il)-4-(4-fluor-2-metil-fenil)-piridin-3-il)-n-metil-isobutiramida. |
PL1643998T3 (pl) * | 2003-07-03 | 2008-01-31 | Hoffmann La Roche | Podwójni antagoniści NK1/NK3 do leczenia schizofrenii |
TWI378101B (en) | 2005-09-09 | 2012-12-01 | Glaxosmithkline Llc | Pyridine derivatives and their use in the treatment of psychotic disorders |
CA2692955A1 (en) * | 2007-12-11 | 2009-07-16 | Cipla Ltd | A new method for preparation of zopiclone and its polymorphs |
GB0814340D0 (en) | 2008-08-05 | 2008-09-10 | Smithkline Beecham Corp | Anhydrous crystol form fo a pyridine derivative |
US8796269B2 (en) * | 2009-08-27 | 2014-08-05 | Nerre Therapeutics Limited | Crystalline 2-(3,5-Bis(trifluoromethyl)phenyl)-N-(4-(4-fluoro-2-methylphenyl)-6-((7S,9aS)-7-(hydroxymethyl)hexahydropyrazino[2,1-c][1,4]oxazin-8(1H)-yl)pyridin-3-yl)-N,2-dimethyl-propanamide of the formula (I), their use in therapy, and process for the preparation of the same |
JP6342662B2 (ja) * | 2014-01-29 | 2018-06-13 | 京セラ株式会社 | ドリルおよびそれを用いた切削加工物の製造方法 |
-
2010
- 2010-08-25 US US13/389,525 patent/US8796269B2/en active Active
- 2010-08-25 CA CA2772168A patent/CA2772168C/en active Active
- 2010-08-25 ES ES10747619.4T patent/ES2440938T3/es active Active
- 2010-08-25 WO PCT/EP2010/062420 patent/WO2011023733A1/en active Application Filing
- 2010-08-25 BR BR112012003435A patent/BR112012003435A2/pt not_active Application Discontinuation
- 2010-08-25 SG SG2012007464A patent/SG178231A1/en unknown
- 2010-08-25 MX MX2012002369A patent/MX2012002369A/es active IP Right Grant
- 2010-08-25 AU AU2010288502A patent/AU2010288502B2/en active Active
- 2010-08-25 EA EA201270302A patent/EA021411B1/ru not_active IP Right Cessation
- 2010-08-25 PL PL10747619T patent/PL2470545T3/pl unknown
- 2010-08-25 JP JP2012526048A patent/JP2013503134A/ja active Pending
- 2010-08-25 EP EP10747619.4A patent/EP2470545B1/en active Active
- 2010-08-25 DK DK10747619.4T patent/DK2470545T3/da active
- 2010-08-25 IN IN1292DEN2012 patent/IN2012DN01292A/en unknown
- 2010-08-25 CN CN201080037918.3A patent/CN102639536B/zh active Active
- 2010-08-25 KR KR1020127004865A patent/KR20120056258A/ko not_active Application Discontinuation
-
2012
- 2012-02-02 ZA ZA2012/00812A patent/ZA201200812B/en unknown
- 2012-02-02 IL IL217922A patent/IL217922A/en active IP Right Grant
-
2015
- 2015-07-13 JP JP2015139845A patent/JP6404186B2/ja active Active
-
2017
- 2017-06-09 JP JP2017114602A patent/JP2017193564A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
ES2440938T3 (es) | 2014-01-31 |
EA201270302A1 (ru) | 2012-07-30 |
PL2470545T3 (pl) | 2014-03-31 |
CA2772168A1 (en) | 2011-03-03 |
IL217922A (en) | 2016-06-30 |
EP2470545B1 (en) | 2013-10-09 |
AU2010288502B2 (en) | 2013-12-12 |
WO2011023733A1 (en) | 2011-03-03 |
JP2013503134A (ja) | 2013-01-31 |
AU2010288502A1 (en) | 2012-02-23 |
ZA201200812B (en) | 2013-03-27 |
MX2012002369A (es) | 2012-03-29 |
US8796269B2 (en) | 2014-08-05 |
JP2016000739A (ja) | 2016-01-07 |
US20120157450A1 (en) | 2012-06-21 |
EA021411B1 (ru) | 2015-06-30 |
IL217922A0 (en) | 2012-03-29 |
CN102639536B (zh) | 2015-03-18 |
CN102639536A (zh) | 2012-08-15 |
JP2017193564A (ja) | 2017-10-26 |
SG178231A1 (en) | 2012-03-29 |
DK2470545T3 (da) | 2014-01-13 |
JP6404186B2 (ja) | 2018-10-10 |
BR112012003435A2 (pt) | 2016-02-23 |
CA2772168C (en) | 2019-01-08 |
EP2470545A1 (en) | 2012-07-04 |
KR20120056258A (ko) | 2012-06-01 |
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