IN2012DN01972A - - Google Patents
Download PDFInfo
- Publication number
- IN2012DN01972A IN2012DN01972A IN1972DEN2012A IN2012DN01972A IN 2012DN01972 A IN2012DN01972 A IN 2012DN01972A IN 1972DEN2012 A IN1972DEN2012 A IN 1972DEN2012A IN 2012DN01972 A IN2012DN01972 A IN 2012DN01972A
- Authority
- IN
- India
- Prior art keywords
- hydrophilic
- hydrophobic
- emulsions
- common intersection
- channels
- Prior art date
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
- B01F25/40—Static mixers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F33/00—Other mixers; Mixing plants; Combinations of mixers
- B01F33/30—Micromixers
- B01F33/3035—Micromixers using surface tension to mix, move or hold the fluids
- B01F33/30351—Micromixers using surface tension to mix, move or hold the fluids using hydrophilic/hydrophobic surfaces
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
- B01F23/40—Mixing liquids with liquids; Emulsifying
- B01F23/41—Emulsifying
- B01F23/414—Emulsifying characterised by the internal structure of the emulsion
- B01F23/4144—Multiple emulsions, in particular double emulsions, e.g. water in oil in water; Three-phase emulsions
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
- B01F23/40—Mixing liquids with liquids; Emulsifying
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
- B01F23/40—Mixing liquids with liquids; Emulsifying
- B01F23/41—Emulsifying
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/80—Forming a predetermined ratio of the substances to be mixed
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T137/00—Fluid handling
- Y10T137/0318—Processes
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T137/00—Fluid handling
- Y10T137/8593—Systems
- Y10T137/87571—Multiple inlet with single outlet
Landscapes
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dispersion Chemistry (AREA)
- Colloid Chemistry (AREA)
Abstract
The present invention generally relates to emulsions, and more particularly, to multiple emulsions. In one aspect, multiple emulsions are formed using a plurality of channels, such as microfluidic channels, that meet at a common intersection. The multiple emulsions may be created at a single common intersection in some embodiments, unlike other prior art systems where multiple channel intersections are required to create multiple emulsions. For instance, in one set of embodiments, three, four, or more microfluidic channels may intersect at a common intersection, with two or three serving as inlets and one serving as the outlet. In some embodiments, a first fluidic channel may be relatively hydrophobic, while a second fluidic channel is relatively hydrophilic. The third channel, if present, may be relatively hydrophilic or hydrophobic, depending on the application. The outlet channel may be hydrophobic, hydrophilic, or may comprise at least one portion that is relatively hydrophilic and at least one portion that is relatively hydrophilic. By controlling the flow of fluids through the hydrophilic and hydrophobic portions of the channels, multiple emulsions may be created proximate the common intersection, due to interactions between the fluids entering the common intersection. In other embodiments, different patterns of hydrophilic or hydrophobic channels may be used. Other aspects of the invention are generally directed to methods of making and using such systems, kits involving such systems, emulsions created using such systems, or the like.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US23940209P | 2009-09-02 | 2009-09-02 | |
PCT/US2010/047458 WO2011028760A2 (en) | 2009-09-02 | 2010-09-01 | Multiple emulsions created using junctions |
Publications (1)
Publication Number | Publication Date |
---|---|
IN2012DN01972A true IN2012DN01972A (en) | 2015-08-21 |
Family
ID=43649932
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IN1972DEN2012 IN2012DN01972A (en) | 2009-09-02 | 2010-09-01 |
Country Status (8)
Country | Link |
---|---|
US (1) | US20120199226A1 (en) |
EP (1) | EP2473262A4 (en) |
JP (1) | JP2013503742A (en) |
KR (1) | KR20120089662A (en) |
CN (1) | CN102481529A (en) |
BR (1) | BR112012004715A2 (en) |
IN (1) | IN2012DN01972A (en) |
WO (1) | WO2011028760A2 (en) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2008535644A (en) | 2005-03-04 | 2008-09-04 | プレジデント・アンド・フエローズ・オブ・ハーバード・カレツジ | Method and apparatus for the formation of multiple emulsions |
WO2010033200A2 (en) | 2008-09-19 | 2010-03-25 | President And Fellows Of Harvard College | Creation of libraries of droplets and related species |
US20140024023A1 (en) * | 2012-07-23 | 2014-01-23 | Bio- Rad Laboratories, Inc | Droplet generation system with features for sample positioning |
GB2471522B (en) * | 2009-07-03 | 2014-01-08 | Cambridge Entpr Ltd | Microfluidic devices |
CN102574078B (en) | 2009-09-02 | 2016-05-18 | 哈佛学院院长等 | Use and spray the multiple emulsion producing with other technology |
KR101243147B1 (en) | 2011-03-15 | 2013-03-13 | 충남대학교산학협력단 | Method for selective surface modification of microfluidic chip channel and preparation of microfluidic chip for multiple emulsion |
JP6122843B2 (en) | 2011-05-23 | 2017-04-26 | プレジデント アンド フェローズ オブ ハーバード カレッジ | Emulsion control including multiple emulsions |
EP3120923A3 (en) | 2011-07-06 | 2017-03-01 | President and Fellows of Harvard College | Article comprising a particle having a shell and a fluid |
US20130064862A1 (en) | 2011-08-30 | 2013-03-14 | Basf Se | Systems and methods for shell encapsulation |
CN102553504B (en) * | 2012-01-18 | 2014-12-17 | 朗盛(常州)有限公司 | Preparation method of emulsion, leather care emulsion, and use leather care emulsion |
WO2013155531A2 (en) * | 2012-04-13 | 2013-10-17 | Bio-Rad Laboratories, Inc. | Sample holder with a well having a wicking promoter |
EP2986385B1 (en) * | 2013-04-17 | 2018-02-14 | Bio-rad Laboratories, Inc. | Method of making a droplet-generating device |
US20160279068A1 (en) | 2013-11-08 | 2016-09-29 | President And Fellows Of Harvard College | Microparticles, methods for their preparation and use |
WO2015160919A1 (en) | 2014-04-16 | 2015-10-22 | President And Fellows Of Harvard College | Systems and methods for producing droplet emulsions with relatively thin shells |
CA2966915A1 (en) | 2014-11-24 | 2016-06-02 | The Procter & Gamble Company | Methods for encapsulation of actives within droplets and other compartments |
CA3001679A1 (en) | 2015-10-13 | 2017-04-20 | President And Fellows Of Harvard College | Systems and methods for making and using gel microspheres |
CN106492716B (en) * | 2016-12-20 | 2024-01-30 | 中国工程物理研究院激光聚变研究中心 | Integrated double-emulsion particle generating device and processing method thereof |
EP3625353B1 (en) | 2017-05-18 | 2022-11-30 | 10X Genomics, Inc. | Methods and systems for sorting droplets and beads |
US10544413B2 (en) | 2017-05-18 | 2020-01-28 | 10X Genomics, Inc. | Methods and systems for sorting droplets and beads |
US10610865B2 (en) | 2017-08-22 | 2020-04-07 | 10X Genomics, Inc. | Droplet forming devices and system with differential surface properties |
WO2019083852A1 (en) | 2017-10-26 | 2019-05-02 | 10X Genomics, Inc. | Microfluidic channel networks for partitioning |
US20190321791A1 (en) * | 2018-04-19 | 2019-10-24 | President And Fellows Of Harvard College | Apparatus and method for forming emulsions |
EP3917654A1 (en) * | 2019-01-31 | 2021-12-08 | Samplix ApS | A microfluidic device and a method for provision of double emulsion droplets |
JPWO2022107898A1 (en) * | 2020-11-20 | 2022-05-27 |
Family Cites Families (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS59131355A (en) * | 1983-01-17 | 1984-07-28 | 森下仁丹株式会社 | Multiple soft capsule |
US6623788B1 (en) * | 2000-07-25 | 2003-09-23 | Seagate Technology Llc | Defect-free patterning of sol-gel-coated substrates for magnetic recording media |
WO2002068104A1 (en) * | 2001-02-23 | 2002-09-06 | Japan Science And Technology Corporation | Process for producing emulsion and microcapsules and apparatus therefor |
JP3860186B2 (en) * | 2001-02-23 | 2006-12-20 | 独立行政法人科学技術振興機構 | Emulsion production equipment |
JP4186637B2 (en) * | 2002-11-06 | 2008-11-26 | 東ソー株式会社 | Particle manufacturing method and microchannel structure therefor |
US7595195B2 (en) * | 2003-02-11 | 2009-09-29 | The Regents Of The University Of California | Microfluidic devices for controlled viscous shearing and formation of amphiphilic vesicles |
JP2006522303A (en) * | 2003-03-31 | 2006-09-28 | ベール ゲーエムベーハー ウント コー カーゲー | Heat exchanger and surface treatment method thereof |
JP4341372B2 (en) * | 2003-10-30 | 2009-10-07 | コニカミノルタホールディングス株式会社 | Liquid mixing method, mixing apparatus and mixing system |
JP4042683B2 (en) * | 2003-11-17 | 2008-02-06 | 東ソー株式会社 | Microchannel structure and microparticle manufacturing method using the same |
JP3777427B2 (en) * | 2003-11-25 | 2006-05-24 | 独立行政法人食品総合研究所 | Emulsion production method and production apparatus |
JP4305145B2 (en) * | 2003-11-25 | 2009-07-29 | 東ソー株式会社 | Particle production method using micro flow channel |
JP4777238B2 (en) * | 2004-03-23 | 2011-09-21 | 独立行政法人科学技術振興機構 | Method and apparatus for generating microdroplets |
JP4461900B2 (en) * | 2004-05-10 | 2010-05-12 | 富士ゼロックス株式会社 | Method for feeding fine particle dispersion and liquid feeding device for fine particle dispersion |
US20070047388A1 (en) * | 2005-08-25 | 2007-03-01 | Rockwell Scientific Licensing, Llc | Fluidic mixing structure, method for fabricating same, and mixing method |
US7776927B2 (en) * | 2007-03-28 | 2010-08-17 | President And Fellows Of Harvard College | Emulsions and techniques for formation |
WO2009048532A2 (en) * | 2007-10-05 | 2009-04-16 | President And Fellows Of Harvard College | Formation of particles for ultrasound application, drug release, and other uses, and microfluidic methods of preparation |
US9011777B2 (en) * | 2008-03-21 | 2015-04-21 | Lawrence Livermore National Security, Llc | Monodisperse microdroplet generation and stopping without coalescence |
US8802027B2 (en) * | 2008-03-28 | 2014-08-12 | President And Fellows Of Harvard College | Surfaces, including microfluidic channels, with controlled wetting properties |
KR101132732B1 (en) * | 2008-11-26 | 2012-04-06 | 한국과학기술연구원 | Intelligent porous biodegradable polymer scaffolds for in situ tissue regeneration and method for the preparation thereof |
US9446360B2 (en) * | 2009-05-07 | 2016-09-20 | Universite De Strasbourg | Microfluidic system and methods for highly selective droplet fusion |
GB2471522B (en) * | 2009-07-03 | 2014-01-08 | Cambridge Entpr Ltd | Microfluidic devices |
-
2010
- 2010-09-01 KR KR1020127008216A patent/KR20120089662A/en not_active Application Discontinuation
- 2010-09-01 US US13/390,584 patent/US20120199226A1/en not_active Abandoned
- 2010-09-01 JP JP2012527993A patent/JP2013503742A/en active Pending
- 2010-09-01 CN CN2010800390182A patent/CN102481529A/en active Pending
- 2010-09-01 IN IN1972DEN2012 patent/IN2012DN01972A/en unknown
- 2010-09-01 EP EP10814398.3A patent/EP2473262A4/en not_active Withdrawn
- 2010-09-01 WO PCT/US2010/047458 patent/WO2011028760A2/en active Application Filing
- 2010-09-01 BR BR112012004715A patent/BR112012004715A2/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
JP2013503742A (en) | 2013-02-04 |
US20120199226A1 (en) | 2012-08-09 |
EP2473262A4 (en) | 2015-12-02 |
KR20120089662A (en) | 2012-08-13 |
WO2011028760A2 (en) | 2011-03-10 |
WO2011028760A3 (en) | 2011-07-14 |
BR112012004715A2 (en) | 2017-05-23 |
CN102481529A (en) | 2012-05-30 |
EP2473262A2 (en) | 2012-07-11 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IN2012DN01972A (en) | ||
TW200626225A (en) | Mixer and mixing method | |
DE502006000086D1 (en) | FLOW CONTROL | |
MX339887B (en) | Systems for the control and use of fluids and particles. | |
WO2007127322A3 (en) | Flow distribution channels to control flow in process channels | |
MX2013011876A (en) | Selectively variable flow restrictor for use in a subterranean well. | |
SG149889A1 (en) | Multilayer hydrodynamic sheath flow structure | |
ATE491636T1 (en) | AERODYNAMIC FLOW SYSTEM AND ASSOCIATED METHOD | |
ATE313378T1 (en) | MICROFLUIDIC DEVICES WITH DISTRIBUTION INLETS | |
MY178064A (en) | Flow conditioner and method of designing same | |
DE502006007046D1 (en) | FORMATION OF AN EMULSION IN A FLUIDIC MICROSYSTEM | |
MX2012001982A (en) | Flow path control based on fluid characteristics to thereby variably resist flow in a subterranean well. | |
ATE445115T1 (en) | FOUR WAY VALVE ARRANGEMENT WITH TWO OUTLETS | |
WO2007024410A3 (en) | Fluidic mixing structure, method for fabricating same, and mixing method | |
DE602006015435D1 (en) | NOISE-REDUCING LIQUID FLOWS FOR FLOW REGULATORS | |
MA32348B1 (en) | Differential pressure gauge | |
WO2007120402A3 (en) | Device and method for creating hydrodynamic cavitation in fluids | |
EP4218993A3 (en) | Fluidic device | |
WO2009025136A1 (en) | Resin pipe fitting and method for producing the same | |
DK3004527T3 (en) | Choker | |
CA2900708C (en) | Mixing of fluids in fluidic systems | |
WO2008018036A3 (en) | Micro-fluidic system | |
WO2015071675A3 (en) | Servo valves | |
MX367368B (en) | Shower head with rotatable control disk. | |
BR112017026602A2 (en) | microfluidic device |