[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

IN164615B - - Google Patents

Info

Publication number
IN164615B
IN164615B IN652/CAL/85A IN652CA1985A IN164615B IN 164615 B IN164615 B IN 164615B IN 652CA1985 A IN652CA1985 A IN 652CA1985A IN 164615 B IN164615 B IN 164615B
Authority
IN
India
Prior art keywords
substituents
chem
compounds
pharmaceutically acceptable
acceptable salts
Prior art date
Application number
IN652/CAL/85A
Other languages
English (en)
Inventor
Edward S Neiss
John T Suh
John R Regan
Jeffrey N Barton
Jerry W Skiles
Paul Menard
James J Mencel
Original Assignee
Usv Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/649,797 external-priority patent/US4746676A/en
Priority claimed from US06/752,695 external-priority patent/US4749698A/en
Application filed by Usv Pharma Corp filed Critical Usv Pharma Corp
Publication of IN164615B publication Critical patent/IN164615B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06191Dipeptides containing heteroatoms different from O, S, or N
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/022Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
    • C07K5/0222Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06008Dipeptides with the first amino acid being neutral
    • C07K5/06078Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
IN652/CAL/85A 1984-09-12 1985-09-16 IN164615B (xx)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/649,797 US4746676A (en) 1984-09-12 1984-09-12 Carboxyalkyl dipeptide compounds
US06/752,695 US4749698A (en) 1985-07-08 1985-07-08 Antihypertensive derivatives

Publications (1)

Publication Number Publication Date
IN164615B true IN164615B (xx) 1989-04-22

Family

ID=27095707

Family Applications (1)

Application Number Title Priority Date Filing Date
IN652/CAL/85A IN164615B (xx) 1984-09-12 1985-09-16

Country Status (13)

Country Link
EP (1) EP0175266B1 (xx)
KR (1) KR860002464A (xx)
AT (1) ATE135711T1 (xx)
AU (1) AU578489B2 (xx)
CA (1) CA1288893C (xx)
DE (1) DE3588094T2 (xx)
DK (1) DK412985A (xx)
ES (1) ES8609364A1 (xx)
FI (1) FI89716C (xx)
IL (1) IL76345A (xx)
IN (1) IN164615B (xx)
NO (1) NO169442C (xx)
NZ (1) NZ213432A (xx)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5629345A (en) * 1993-07-23 1997-05-13 Vide Pharmaceuticals Methods and compositions for ATP-sensitive K+ channel inhibition for lowering intraocular pressure
US5965620A (en) * 1993-07-23 1999-10-12 Vide Pharmaceuticals Methods and compositions for ATP-sensitive K+ channel inhibition for lowering intraocular pressure
WO1995034577A1 (en) * 1994-06-16 1995-12-21 Smithkline Beecham Corporation Template directed cyclization
AU780612C (en) 1999-10-14 2005-10-20 Curis, Inc. Mediators of hedgehog signaling pathways, compositions and uses related thereto
EP1191662B1 (de) 2000-09-21 2010-06-16 ABB Schweiz AG Konfiguration eines Leitsystems einer elektrischen Schaltanlage
DK1966130T3 (da) 2005-12-23 2014-02-10 Zealand Pharma As Modificerede lysin-mimetiske forbindelser
EP2074087A2 (en) 2006-12-21 2009-07-01 Wyeth Synthesis of pyrrolidine compounds
WO2018202865A1 (en) 2017-05-05 2018-11-08 Zealand Pharma A/S Gap junction intercellular communication modulators and their use for the treatment of diabetic eye disease

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5683483A (en) * 1979-12-13 1981-07-08 Santen Pharmaceut Co Ltd Thiazolidine compound
US4350704A (en) * 1980-10-06 1982-09-21 Warner-Lambert Company Substituted acyl derivatives of octahydro-1H-indole-2-carboxylic acids
EP0048159A3 (en) * 1980-09-17 1982-05-12 University Of Miami Novel carboxyalkyl peptides and thioethers and ethers of peptides as antihypertensive agents
US4462943A (en) * 1980-11-24 1984-07-31 E. R. Squibb & Sons, Inc. Carboxyalkyl amino acid derivatives of various substituted prolines
FR2501399B1 (fr) * 1981-03-03 1987-06-19 France Etat Dispositif d'affichage de messages graphiques transmis par des systemes de videotex
EP0080822A1 (en) * 1981-11-27 1983-06-08 Beecham Group Plc Anti-hypertensive prolinol-based peptides
DE3360065D1 (en) * 1982-03-08 1985-03-28 Schering Corp Carboxyalkyl dipeptides, processes for their production and pharmaceutical compositions containing them
ZA832762B (en) * 1982-04-30 1983-12-28 Squibb & Sons Inc Substituted 4-phenoxy prolines
AU1643283A (en) * 1982-07-19 1984-01-26 E.R. Squibb & Sons, Inc. Substituted peptides
US4623729A (en) * 1982-07-22 1986-11-18 E. R. Squibb & Sons, Inc. Acylalkylaminocarbonyl substituted amino and imino acid compounds
US4499079A (en) * 1982-11-18 1985-02-12 E. R. Squibb & Sons, Inc. Carboxy and substituted carboxy alkanoyl and cycloalkanoyl peptides
DK156484A (da) * 1983-03-16 1984-09-17 Usv Pharma Corp Aminosyrederivater
ZA843899B (en) * 1983-05-23 1984-12-24 Usv Pharma Corp Compounds for treating hypertension

Also Published As

Publication number Publication date
AU4733185A (en) 1986-03-20
NZ213432A (en) 1988-11-29
CA1288893C (en) 1991-09-10
FI853494L (fi) 1986-03-13
EP0175266A3 (en) 1988-08-03
KR860002464A (ko) 1986-04-26
DK412985A (da) 1986-03-13
IL76345A0 (en) 1986-01-31
ES8609364A1 (es) 1986-07-16
DE3588094T2 (de) 1996-08-22
AU578489B2 (en) 1988-10-27
NO853551L (no) 1986-03-13
IL76345A (en) 1988-12-30
ATE135711T1 (de) 1996-04-15
NO169442C (no) 1992-06-24
FI89716C (fi) 1993-11-10
DE3588094D1 (de) 1996-04-25
FI89716B (fi) 1993-07-30
EP0175266A2 (en) 1986-03-26
FI853494A0 (fi) 1985-09-12
NO169442B (no) 1992-03-16
EP0175266B1 (en) 1996-03-20
DK412985D0 (da) 1985-09-11
ES546866A0 (es) 1986-07-16

Similar Documents

Publication Publication Date Title
DE3669876D1 (de) 3,4-dihydrobenzopyranderivate.
DE3585980D1 (de) Hydrazinderivate und ihre verwendung.
IT8519908A0 (it) Procedimento per produrre difenilammine oppure n,n'-difenil-fenilendiammine.
ZA872825B (en) New pyrimidine derivatives,having fungicidal activity
IN164615B (xx)
ES8704875A1 (es) Procedimiento de producir compuestos para tratar la hiper- tension
IT8422150A0 (it) Composti dotati di attivita'antiallergica.
ES8602021A1 (es) Procedimiento de preparar compuestos espirociclicos antihi- pertensivos
DE3585315D1 (de) 5,6,7,8-tetrafluoranthrachinonderivate.
DE3763413D1 (en) Erythromycylamin-derivate.
FI850197A0 (fi) Foerfarande foer kontroll av byggdelar med hjaelp av en virvelstroem, i synnerhet i kaerntekniska anlaeggningar.
DE3586745D1 (de) 9,11-epoxy-21-hydroxypregnan-derivate.
FI865244A0 (fi) Foerfarande foer framstaellning av optiskt aktiva 2-klor-12-(3-dimetylamino-2-metylpropyl)-12h-dibenzo-/d,g//1,3,6/ dioxazociner.
ES8606874A1 (es) Metodo de preparacion de compuestos espiroamidoamino anti- hipertensivos
EP0153755A3 (en) Compounds for treating hypertension
IT8719846A0 (it) Composti dotati di attivita'antiallergica.
IT8719845A0 (it) Composti dotati di attivita'antiallergica.
IT8433319V0 (it) Spiralex maxima securitas 2000 n. 5cu 285,70 mg
SU1132513A1 (ru) 2-метиламино-4-оксо-3,6,6-триметил-5,6-дигидро-8н-пирано[4′,3′ : 4,5]тиено[2,3-d]пиримидин или его соли, обладающие противосудорожной активностью
SU1432991A1 (ru) 4-Метил-5-(4-метилфениламино)-1,2,3-триазол, обладающий противовоспалительной активностью
IT8323995A0 (it) Composto ad attivita'antiipertensiva.
DE3568161D1 (de) 15(r+s)-fluorine-11,15-didesoxyprostaglandin e 1? derivatives
FI853792A0 (fi) Regleringsanordning foer sugvolymen i en pipett.
IT8719844A0 (it) Composti dotati di attivita'antiallergica.