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IL94416A - Pharmaceutical compositions containing dihydrospirorenone - Google Patents

Pharmaceutical compositions containing dihydrospirorenone

Info

Publication number
IL94416A
IL94416A IL94416A IL9441690A IL94416A IL 94416 A IL94416 A IL 94416A IL 94416 A IL94416 A IL 94416A IL 9441690 A IL9441690 A IL 9441690A IL 94416 A IL94416 A IL 94416A
Authority
IL
Israel
Prior art keywords
dihydrospirorenone
pharmaceutical compositions
compositions containing
treatment
hormonal
Prior art date
Application number
IL94416A
Other versions
IL94416A0 (en
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6380839&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL94416(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Schering Ag filed Critical Schering Ag
Publication of IL94416A0 publication Critical patent/IL94416A0/en
Publication of IL94416A publication Critical patent/IL94416A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A61K31/585—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin containing lactone rings, e.g. oxandrolone, bufalin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Dental Preparations (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

Pharmaceutical compositions for treatment of hormonal irregularities during premenopause, for hormonal substitution therapy during menopause, for treatment of androgen-induced disorders and for contraception, comprising dihydrospirorenone and optionally further comprising an effective amount of an estrogenic or gestagenic compound as active ingredient therein, in combination with a pharmaceutically acceptable carrier.
IL94416A 1989-05-16 1990-05-16 Pharmaceutical compositions containing dihydrospirorenone IL94416A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3916112A DE3916112A1 (en) 1989-05-16 1989-05-16 DIHYDROSPIRORENONE AS AN ANTIANDROGEN

Publications (2)

Publication Number Publication Date
IL94416A0 IL94416A0 (en) 1991-03-10
IL94416A true IL94416A (en) 1997-07-13

Family

ID=6380839

Family Applications (1)

Application Number Title Priority Date Filing Date
IL94416A IL94416A (en) 1989-05-16 1990-05-16 Pharmaceutical compositions containing dihydrospirorenone

Country Status (20)

Country Link
US (1) US5569652A (en)
EP (1) EP0398460B1 (en)
JP (1) JP2848919B2 (en)
CN (1) CN1033948C (en)
AT (1) ATE154881T1 (en)
AU (1) AU642876B2 (en)
BR (1) BR1101055A (en)
CA (1) CA2016780C (en)
DD (1) DD294417A5 (en)
DE (3) DE3916112A1 (en)
DK (1) DK0398460T3 (en)
ES (1) ES2106728T3 (en)
GR (1) GR3024861T3 (en)
HU (1) HU213408B (en)
IE (1) IE81143B1 (en)
IL (1) IL94416A (en)
LU (1) LU91065I2 (en)
NL (1) NL300221I2 (en)
PT (1) PT94038B (en)
ZA (1) ZA903754B (en)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4321957C2 (en) * 1993-07-01 1995-09-28 Marika Dr Med Ehrlich Use of a hormonal agent to treat acne
DE4344462C2 (en) 1993-12-22 1996-02-01 Schering Ag Composition for contraception
DE19651000A1 (en) * 1996-12-01 1998-06-04 Schering Ag Oxyiminopregnancarbolactone
EP2305267A3 (en) 1999-08-31 2011-08-17 Bayer Schering Pharma Aktiengesellschaft Pharmaceutical combination of ethinylestradiol and drospirenone for use as a contraceptive
EP1380301B1 (en) * 1999-08-31 2009-01-14 Bayer Schering Pharma Aktiengesellschaft Pharmaceutical combination of ethinylestradiol and dropirenone for use as a contraceptive
US6787531B1 (en) 1999-08-31 2004-09-07 Schering Ag Pharmaceutical composition for use as a contraceptive
US20020132801A1 (en) * 2001-01-11 2002-09-19 Schering Aktiengesellschaft Drospirenone for hormone replacement therapy
EP1216712A1 (en) * 2000-12-20 2002-06-26 Schering Aktiengesellschaft Cyclodextrin-drospirenone inclusion complexes
AU2002222387A1 (en) * 2000-12-20 2002-07-01 Schering Aktiengesellschaft Cyclodextrin-drospirenone inclusion complexes
EP1216713A1 (en) 2000-12-20 2002-06-26 Schering Aktiengesellschaft Compositions of estrogen-cyclodextrin complexes
MXPA04009033A (en) * 2002-03-18 2005-01-25 Pharmacia Corp Combination of an aldosterone receptor antagonist and nicotinic acid or a nicotinic acid derivative.
WO2003080069A1 (en) * 2002-03-18 2003-10-02 Pharmacia Corporation Combination of an aldosterone receptor antagonist and a bile acid sequestering agent
WO2004070048A1 (en) * 2003-02-07 2004-08-19 Pharmacia & Upjohn Company Llc A microbial process to prepare 5-androsten-3beta, 7alpha, 15alpha-triol-17-one and related analogues
MY142989A (en) * 2004-03-10 2011-02-14 Bayer Schering Pharma Ag Stabilised supersaturated solids of lipophilic drugs
US20050220825A1 (en) * 2004-03-10 2005-10-06 Adrian Funke Molecular dispersions of drospirenone
WO2005087194A1 (en) * 2004-03-10 2005-09-22 Schering Aktiengesellschaft Compositions comprising drospirenone molecularly dispersed
DE102004026671A1 (en) 2004-05-28 2005-12-15 Grünenthal GmbH Dosage form for hormonal contraception
DE102004026679A1 (en) 2004-05-28 2005-12-15 Grünenthal GmbH Hormonal contraceptive containing a combination of ethinylestradiol and chlormadinone acetate
DE102004026670A1 (en) 2004-05-28 2005-12-15 Grünenthal GmbH Hormonal contraceptive containing a combination of ethinylestradiol and chlormadinone acetate
ITMI20042338A1 (en) * 2004-12-06 2005-03-06 Ind Chimica Srl PROCESS FOR THE PREPARATION OF DROSPIRENONE
US8475838B2 (en) * 2005-06-03 2013-07-02 Sandoz Ag Rapidly-dissolving pharmaceutical composition for inhibiting ovulation
PL1746101T5 (en) * 2005-07-21 2014-11-28 Bayer Pharma AG Process for the production of Oxo-pregn-4-en-21,17-carbolactonen by metal free oxidation of 17-(3-hydroxypropyl)-3,17-dihydroxyandrostanes
US7319154B2 (en) 2005-07-21 2008-01-15 Bayer Schering Pharma Ag Process for the production of 3-oxo-pregn-4-ene-21, 17-carbolactones by the metal free oxidation of 17-(3-hydroxypropyl)-3, 17-dihydroxyandrostanes
US20070275941A1 (en) * 2006-05-17 2007-11-29 Vladimir Hanes Salt sensitivity and prevention of hypertension with drospirenone
US20090269403A1 (en) * 2008-04-24 2009-10-29 Shaked Ze Ev Oral contraceptive dosage forms and methods of making such dosage forms
US9301920B2 (en) 2012-06-18 2016-04-05 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
BR112014012444B1 (en) 2011-11-23 2021-12-14 Therapeuticsmd, Inc A PHARMACEUTICAL COMPOSITION COMPRISING SOLUBILIZED ESTRADIOL, PROGESTERONE AND A SOLUBILIZING AGENT, AND USES THEREOF TO TREAT A MENOPAUSE-RELATED SYMPTOM IN A WOMAN
US20130338122A1 (en) 2012-06-18 2013-12-19 Therapeuticsmd, Inc. Transdermal hormone replacement therapies
US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US20150196640A1 (en) 2012-06-18 2015-07-16 Therapeuticsmd, Inc. Progesterone formulations having a desirable pk profile
US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10537581B2 (en) 2012-12-21 2020-01-21 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10471072B2 (en) 2012-12-21 2019-11-12 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US9180091B2 (en) 2012-12-21 2015-11-10 Therapeuticsmd, Inc. Soluble estradiol capsule for vaginal insertion
US11246875B2 (en) 2012-12-21 2022-02-15 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11266661B2 (en) 2012-12-21 2022-03-08 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10568891B2 (en) 2012-12-21 2020-02-25 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10206932B2 (en) 2014-05-22 2019-02-19 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
MX2018011705A (en) 2016-04-01 2019-06-10 Therapeuticsmd Inc Steroid hormone pharmaceutical composition.
US10286077B2 (en) 2016-04-01 2019-05-14 Therapeuticsmd, Inc. Steroid hormone compositions in medium chain oils
US11633405B2 (en) 2020-02-07 2023-04-25 Therapeuticsmd, Inc. Steroid hormone pharmaceutical formulations

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2652761C2 (en) * 1976-11-16 1985-11-21 Schering AG, 1000 Berlin und 4709 Bergkamen 15,16-methylene-spirolactones, processes for their preparation and pharmaceuticals containing them
DE3022337A1 (en) * 1980-06-11 1982-01-07 Schering Ag Berlin Und Bergkamen, 1000 Berlin Compsns. for contraception or treatment of gynaecological disorders - contg. 6 beta, 7 beta; 15 delta, 16 beta-di:methylene-3-oxo-4-androstene-17(beta-1')-spiro-5'-per:hyd- ro-furan-2'-one
US4347245A (en) * 1981-05-26 1982-08-31 German Shapiro Spironolactone-containing composition and use thereof
JPS59139400A (en) * 1983-01-31 1984-08-10 Shionogi & Co Ltd Steroid derivative with antialdosteronic activity
DE3402329A1 (en) * 1984-01-20 1985-08-01 Schering AG, 1000 Berlin und 4709 Bergkamen 6,6-ETHYLENE-15,16-METHYLENE-3-OXO-17 (ALPHA) -PREGN-4-EN-21,17-CARBOLACTONE, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM
US4855289A (en) * 1984-06-04 1989-08-08 Wester Per O Combination of two active substances
US4729999A (en) * 1984-10-12 1988-03-08 Bcm Technologies Antiestrogen therapy for symptoms of estrogen deficiency
DE3615376A1 (en) * 1986-05-07 1987-11-12 Schering Ag 2,2; 6,6-DIETHYLENE-3-OXO-17 (ALPHA) -PREGN-4-EN-21,17-CARBOLACTONE, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM
IE61236B1 (en) * 1986-07-15 1994-10-19 American Home Prod Combination dosage form for pre-menopausal women

Also Published As

Publication number Publication date
CA2016780C (en) 2000-07-11
GR3024861T3 (en) 1998-01-30
AU5509490A (en) 1990-11-22
HUT54500A (en) 1991-03-28
HU213408B (en) 1997-06-30
EP0398460B1 (en) 1997-07-02
CN1047299A (en) 1990-11-28
DE122004000006I1 (en) 2006-06-08
US5569652A (en) 1996-10-29
DE3916112A1 (en) 1990-11-22
JP2848919B2 (en) 1999-01-20
EP0398460A2 (en) 1990-11-22
JPH0395121A (en) 1991-04-19
LU91065I2 (en) 2004-03-30
DE3916112C2 (en) 1992-04-30
ES2106728T3 (en) 1997-11-16
PT94038B (en) 1997-06-30
IL94416A0 (en) 1991-03-10
PT94038A (en) 1991-01-08
ZA903754B (en) 1991-02-27
AU642876B2 (en) 1993-11-04
DE59010730D1 (en) 1997-08-07
NL300221I1 (en) 2006-04-03
HU903045D0 (en) 1990-09-28
CA2016780A1 (en) 1990-11-16
CN1033948C (en) 1997-02-05
IE81143B1 (en) 2000-04-19
BR1101055A (en) 2000-08-08
DD294417A5 (en) 1991-10-02
IE901738L (en) 1990-11-16
EP0398460A3 (en) 1991-09-25
NL300221I2 (en) 2006-11-01
ATE154881T1 (en) 1997-07-15
DK0398460T3 (en) 1998-02-16

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