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IL93456A - D2 Aphimer of A1- hydroxyvitamin and pharmaceutical preparations containing it - Google Patents

D2 Aphimer of A1- hydroxyvitamin and pharmaceutical preparations containing it

Info

Publication number
IL93456A
IL93456A IL9345690A IL9345690A IL93456A IL 93456 A IL93456 A IL 93456A IL 9345690 A IL9345690 A IL 9345690A IL 9345690 A IL9345690 A IL 9345690A IL 93456 A IL93456 A IL 93456A
Authority
IL
Israel
Prior art keywords
vitamin
hydroxy
compound
epi
hydroxyvitamin
Prior art date
Application number
IL9345690A
Other languages
English (en)
Hebrew (he)
Other versions
IL93456A0 (en
Original Assignee
Wisconsin Alumni Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wisconsin Alumni Res Found filed Critical Wisconsin Alumni Res Found
Publication of IL93456A0 publication Critical patent/IL93456A0/xx
Publication of IL93456A publication Critical patent/IL93456A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Endocrinology (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL9345690A 1989-03-09 1990-02-20 D2 Aphimer of A1- hydroxyvitamin and pharmaceutical preparations containing it IL93456A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/321,254 US4973584A (en) 1989-03-09 1989-03-09 Novel 1α-hydroxyvitamin D2 epimer and derivatives

Publications (2)

Publication Number Publication Date
IL93456A0 IL93456A0 (en) 1990-11-29
IL93456A true IL93456A (en) 1994-02-27

Family

ID=23249837

Family Applications (1)

Application Number Title Priority Date Filing Date
IL9345690A IL93456A (en) 1989-03-09 1990-02-20 D2 Aphimer of A1- hydroxyvitamin and pharmaceutical preparations containing it

Country Status (15)

Country Link
US (1) US4973584A (ja)
EP (1) EP0386793B1 (ja)
JP (1) JPH0737443B2 (ja)
KR (1) KR950005776B1 (ja)
AT (1) ATE90342T1 (ja)
AU (1) AU631618B2 (ja)
CA (1) CA1335105C (ja)
DE (1) DE69001839T2 (ja)
DK (1) DK0386793T3 (ja)
ES (1) ES2055193T3 (ja)
HU (1) HU207040B (ja)
IL (1) IL93456A (ja)
NZ (1) NZ232735A (ja)
RU (1) RU2065851C1 (ja)
WO (1) WO1990010619A1 (ja)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5260290A (en) * 1990-02-14 1993-11-09 Wisconsin Alumni Research Foundation Homologated vitamin D2 compounds and the corresponding 1α-hydroxylated derivatives
US5030772A (en) * 1990-02-14 1991-07-09 Deluca Hector F Process for preparing vitamin D2 compounds and the corresponding 1 α-hydroxylated derivatives
US5756783A (en) * 1990-09-21 1998-05-26 Bone Care International, Inc. 1α-Hydroxy-24-EPI-vitamin D4
US6538037B2 (en) 1991-01-08 2003-03-25 Bone Care International, Inc. Methods for preparation and use of 1α,24(S)-dihydroxyvitamin D2
US6251883B1 (en) 1991-01-08 2001-06-26 Bone Care International, Inc. Methods for preparation and use of 1α,24(S)-dihydroxy vitamin D2
US20040009958A1 (en) * 1991-01-08 2004-01-15 Bone Care International, Inc. Methods for preparation and use of 1alpha,24(S)-dihydroxyvitamin D2
US5786348A (en) * 1991-01-08 1998-07-28 Bone Care International, Inc. Methods for preparation and use of 1α,24(S)-dihydroxy vitamin D2
US5182396A (en) * 1991-03-29 1993-01-26 Nisshin Flour Milling Co., Ltd. 1-hydroxyvitamin d derivatives
AU656829B2 (en) * 1991-12-26 1995-02-16 Wisconsin Alumni Research Foundation 26, 27-dimethylene-1 alpha, 25-dihydroxyvitamin D2 and 26,27-dihydroxyvitamin D2 and methods for preparing same
AU682817B2 (en) * 1992-01-29 1997-10-23 Bone Care International, Inc. 1alpha-hydroxy-24-(epi)-vitamin D4
US5194431A (en) * 1992-07-08 1993-03-16 Wisconsin Alumni Research Foundation 24-cyclopropane vitamin D derivatives
AU4841193A (en) * 1992-08-28 1994-03-29 Lunar Corporation 1alpha,24(S)-dihydroxy vitamin D2, its formation and use
TW267161B (ja) * 1992-11-20 1996-01-01 Hoffmann La Roche
JPH0753384A (ja) * 1993-07-13 1995-02-28 Wisconsin Alumni Res Found ２４−エピ−１α−ヒドロキシビタミンＤ２ を含んでなる骨粗鬆症治療剤
US5565589A (en) * 1993-11-03 1996-10-15 Wisconsin Alumni Research Foundation 17-formyl-5,6-trans-vitamin D compounds
US5373004A (en) * 1993-11-24 1994-12-13 Wisconsin Alumni Research Foundation 26,28-methylene-1α, 25-dihydroxyvitamin D2 compounds
US5661140A (en) * 1994-11-21 1997-08-26 Wisconsin Alumni Research Foundation 18-nor-vitamin D compounds
US5716946A (en) * 1996-02-13 1998-02-10 Wisconsin Alumni Research Foundation Multiple sclerosis treatment
WO2000028982A2 (en) 1998-11-19 2000-05-25 The Board Of Trustees For The University Of Arkansas Increasing bone strength with selected bisphosphonates
CA2366586C (en) * 1999-04-01 2004-06-22 Johns Hopkins University Non-calcemic, antiproliferative, transcriptionally active sulfur-containing analogs of 1.alpha., 25-dihydroxy vitamin d3
US6479474B2 (en) 1999-07-08 2002-11-12 Wisconsin Alumni Research Foundation Dietary calcium as a supplement to vitamin D compound treatment of multiple sclerosis
JP2005500402A (ja) * 2001-08-22 2005-01-06 ジョンズ ホプキンス ユニバーシティ １α，２５−ジヒドロキシビタミンＤ３の２４−硫黄置換類縁体
WO2003106411A1 (en) 2002-06-13 2003-12-24 Johns Hopkins University 24-sulfoximine vitamin d3 compounds
AU2003292920A1 (en) 2002-12-18 2004-07-09 Cytochroma Inc. 25-so2-substituted analogs of 1alpha, 25-dihydroxyvitamin d3 (calcitriol)
NZ545862A (en) * 2003-08-20 2010-01-29 Wisconsin Alumni Res Found 2-Methylene-19-nor-vitamin D2 compounds
SG2014006324A (en) 2009-01-27 2014-03-28 Berg Llc Vitamin d3 and analogs thereof for alleviating side effects associated with chemotherapy
SG10201404883YA (en) 2009-08-14 2014-10-30 Berg Llc Vitamin d3 and analogs thereof for treating alopecia
AU2014274099A1 (en) 2013-05-29 2015-12-24 Berg Llc Preventing or mitigating chemotherapy induced alopecia using vitamin D

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3907843A (en) * 1974-06-14 1975-09-23 Wisconsin Alumni Res Found 1{60 -Hydroxyergocalciferol and processes for preparing same
US3880894A (en) * 1974-05-24 1975-04-29 Wisconsin Alumni Res Found 1,25-Dihydroxyergocalciferol
CH665834A5 (de) * 1983-05-09 1988-06-15 Wisconsin Alumni Res Found Verfahren zur herstellung von 1alpha,25-dihydroxyliertem vitamin d(2) und verwandten verbindungen.
US4769181A (en) * 1983-11-07 1988-09-06 Wisconsin Alumni Research Foundation 1,25-dihydroxyvitamin D2 compounds
US4588528A (en) * 1984-05-31 1986-05-13 Wisconsin Alumni Research Foundation 1,24-dihydroxy-Δ22 -vitamin D3 and process for preparing same
US4612308A (en) * 1984-11-29 1986-09-16 Hoffmann-La Roche Inc. 25,26-Dehydro-1α,23(S,R)-dihydroxycholecalciferol and its epimers
US4717721A (en) * 1985-05-30 1988-01-05 Howard W. Bremer Sidechain homo-vitamin D compounds with preferential anti-cancer activity

Also Published As

Publication number Publication date
RU2065851C1 (ru) 1996-08-27
HU207040B (en) 1993-03-01
KR920700201A (ko) 1992-02-19
WO1990010619A1 (en) 1990-09-20
DK0386793T3 (da) 1993-08-02
AU631618B2 (en) 1992-12-03
US4973584A (en) 1990-11-27
DE69001839T2 (de) 1993-09-16
DE69001839D1 (de) 1993-07-15
JPH03504508A (ja) 1991-10-03
EP0386793B1 (en) 1993-06-09
CA1335105C (en) 1995-04-04
ATE90342T1 (de) 1993-06-15
AU5192590A (en) 1990-10-09
IL93456A0 (en) 1990-11-29
EP0386793A1 (en) 1990-09-12
HU902288D0 (en) 1991-07-29
NZ232735A (en) 1992-07-28
KR950005776B1 (ko) 1995-05-30
JPH0737443B2 (ja) 1995-04-26
ES2055193T3 (es) 1994-08-16

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KB Patent renewed
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RH1 Patent not in force