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IL88183A0 - Intermediates for the preparation of halogenated protease inhibitors - Google Patents

Intermediates for the preparation of halogenated protease inhibitors

Info

Publication number
IL88183A0
IL88183A0 IL88183A IL8818388A IL88183A0 IL 88183 A0 IL88183 A0 IL 88183A0 IL 88183 A IL88183 A IL 88183A IL 8818388 A IL8818388 A IL 8818388A IL 88183 A0 IL88183 A0 IL 88183A0
Authority
IL
Israel
Prior art keywords
intermediates
halogenated
preparation
protease inhibitors
protease
Prior art date
Application number
IL88183A
Other languages
English (en)
Original Assignee
Searle & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Searle & Co filed Critical Searle & Co
Publication of IL88183A0 publication Critical patent/IL88183A0/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/76Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
    • C07C69/78Benzoic acid esters
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/67Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids
    • C07C69/716Esters of keto-carboxylic acids or aldehydo-carboxylic acids
    • C07C69/72Acetoacetic acid esters
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/02Esters of acyclic saturated monocarboxylic acids having the carboxyl group bound to an acyclic carbon atom or to hydrogen
    • C07C69/22Esters of acyclic saturated monocarboxylic acids having the carboxyl group bound to an acyclic carbon atom or to hydrogen having three or more carbon atoms in the acid moiety

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
IL88183A 1987-10-29 1988-10-27 Intermediates for the preparation of halogenated protease inhibitors IL88183A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/114,186 US4803294A (en) 1987-10-29 1987-10-29 Process and intermediates for the preparation of halogenated protease inhibitors

Publications (1)

Publication Number Publication Date
IL88183A0 true IL88183A0 (en) 1989-06-30

Family

ID=22353816

Family Applications (1)

Application Number Title Priority Date Filing Date
IL88183A IL88183A0 (en) 1987-10-29 1988-10-27 Intermediates for the preparation of halogenated protease inhibitors

Country Status (12)

Country Link
US (1) US4803294A (xx)
EP (1) EP0314126A3 (xx)
JP (1) JPH01149754A (xx)
KR (1) KR890006562A (xx)
AU (1) AU2437488A (xx)
DK (1) DK602288A (xx)
FI (1) FI884958A (xx)
IL (1) IL88183A0 (xx)
NO (1) NO884818L (xx)
NZ (1) NZ226749A (xx)
PT (1) PT88870B (xx)
ZA (1) ZA888113B (xx)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7632494B2 (en) * 1999-09-24 2009-12-15 Proteon Therapeutics, Inc. Methods for enlarging the diameter of a biological conduit in a human subject
US7063838B1 (en) * 1999-09-24 2006-06-20 Proteon Therapeutics Llc Methods for treating an artery or vein in a human subject
DE60034694T2 (de) * 1999-09-24 2008-01-17 Proteon Therapeutics, Inc. Verwendung von elastase zur öffnung verstopfter arterien und venen

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4501895A (en) * 1983-05-09 1985-02-26 G.D. Searle & Co. [Halo-4-(4,5-dihydro-4,4-dimethyl-2-oxazolyl)-phenyl]octadecan-ols and -ones
US4469885A (en) * 1983-05-09 1984-09-04 G. D. Searle & Co. Halogenated protease inhibitors
US4499295A (en) * 1983-05-09 1985-02-12 G. D. Searle & Co. Protease inhibitors

Also Published As

Publication number Publication date
NZ226749A (en) 1989-10-27
JPH01149754A (ja) 1989-06-12
FI884958A0 (fi) 1988-10-27
DK602288D0 (da) 1988-10-28
ZA888113B (en) 1989-12-27
DK602288A (da) 1989-04-30
AU2437488A (en) 1989-05-04
NO884818L (no) 1989-05-02
NO884818D0 (no) 1988-10-28
FI884958A (fi) 1989-04-30
EP0314126A3 (en) 1990-01-31
PT88870B (pt) 1993-01-29
EP0314126A2 (en) 1989-05-03
KR890006562A (ko) 1989-06-14
US4803294A (en) 1989-02-07

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