IL88899A - History of 1-phenyl-isoquinoline, their preparation and pharmaceutical preparations containing them - Google Patents

History of 1-phenyl-isoquinoline, their preparation and pharmaceutical preparations containing them

Info

Publication number: IL88899A
Authority: IL; Israel
Prior art keywords: dimethoxy; phenyl; isoquinoline; formula; hydrogen
Prior art date: 1988-01-08

Application number

IL8889989A

Other languages

English (en)

Hebrew (he)

Other versions

IL88899A0 (en

Inventor

Klaus Hasspacher

Reto Naef

Original Assignee

Sandoz Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-01-08

Filing date

1989-01-06

Publication date

1994-07-31

1989-01-06 Application filed by Sandoz Ag filed Critical Sandoz Ag

1989-08-15 Publication of IL88899A0 publication Critical patent/IL88899A0/xx

1994-07-31 Publication of IL88899A publication Critical patent/IL88899A/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
- C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
- C07D217/16—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals substituted by oxygen atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Pulmonology (AREA)
Immunology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Other In-Based Heterocyclic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

IL8889989A 1988-01-08 1989-01-06 History of 1-phenyl-isoquinoline, their preparation and pharmaceutical preparations containing them IL88899A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB888800397A GB8800397D0 (en)	1988-01-08	1988-01-08	Improvements in/relating to organic compounds

Publications (2)

Publication Number	Publication Date
IL88899A0 IL88899A0 (en)	1989-08-15
IL88899A true IL88899A (en)	1994-07-31

Family

ID=10629678

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL8889989A IL88899A (en)	1988-01-08	1989-01-06	History of 1-phenyl-isoquinoline, their preparation and pharmaceutical preparations containing them

Country Status (28)

Country	Link
US (1)	US4980359A (pt)
JP (1)	JPH0649686B2 (pt)
KR (1)	KR0142686B1 (pt)
AT (1)	AT394365B (pt)
AU (1)	AU622429B2 (pt)
BE (1)	BE1002730A3 (pt)
CA (1)	CA1332944C (pt)
CH (1)	CH678727A5 (pt)
DE (1)	DE3900233C2 (pt)
DK (1)	DK5789A (pt)
ES (1)	ES2010071A6 (pt)
FI (1)	FI90865C (pt)
FR (1)	FR2625743B1 (pt)
GB (2)	GB8800397D0 (pt)
GR (1)	GR1002750B (pt)
HU (1)	HU205083B (pt)
IE (1)	IE61914B1 (pt)
IL (1)	IL88899A (pt)
IT (1)	IT1229523B (pt)
LU (1)	LU87423A1 (pt)
MY (1)	MY103963A (pt)
NL (1)	NL8900029A (pt)
NZ (1)	NZ227561A (pt)
PH (1)	PH25640A (pt)
PL (1)	PL156099B1 (pt)
PT (1)	PT89405B (pt)
SE (1)	SE501548C2 (pt)
ZA (1)	ZA89133B (pt)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2723674A (en) *	1951-11-28	1955-11-15	Charles E Harris	Telephone cableman's tent
US3007541A (en) *	1959-02-24	1961-11-07	Jr John B Mast	Temporary covering and support structure therefor
GB8807922D0 (en) *	1988-04-05	1988-05-05	Fujisawa Pharmaceutical Co	Isoquinoline compound & process for preparation thereof
US4956371A (en) *	1989-09-19	1990-09-11	Euroceltique, S.A.	Substituted isoquinolines and methods of using same
GB8921304D0 (en) *	1989-09-20	1989-11-08	Wyeth John & Brother Ltd	New method of treatment and heterocyclic compounds used therein
GB9027055D0 (en) *	1990-12-13	1991-02-06	Sandoz Ltd	Organic compounds
HUT64676A (en) *	1990-12-17	1994-02-28	Shell Int Research	Fungicidal compositions containing isoquinoline derivatives as actvie agent and process for production of the active agents
CA2093577C (en) *	1992-05-07	2006-01-03	Michael Klaus	Alkyl or alkoxy substituted s-heterocyclic retinoids
US5350423A (en) *	1992-09-23	1994-09-27	Burlington Industries Inc.	Fabric finishing procedure
GB9322828D0 (en) *	1993-11-05	1993-12-22	Sandoz Ltd	Organic compounds
US5783184A (en) *	1994-12-23	1998-07-21	Smithkline Beecham Corporation	Method for treatment and diagnosis of IL-5 mediated disorders
US6129913A (en) *	1994-12-23	2000-10-10	Smithkline Beecham Corporation	Recombinant IL-5 antagonists useful in treatment of IL-5 mediated disorders
US7399837B2 (en)	1995-12-22	2008-07-15	Smithkline Beecham Corporation	Recombinant IL-5 antagonists useful in treatment of IL-5 mediated disorders
US5693323A (en) *	1994-12-23	1997-12-02	Smithkline Beecham Corporation	Recombinant IL-5 antagonists useful in treatment of IL-5 mediated disorders
GB9622386D0 (en) *	1996-10-28	1997-01-08	Sandoz Ltd	Organic compounds
IT1296985B1 (it)	1997-12-19	1999-08-03	Zambon Spa	Derivati benzazinici inibitori della fosfodiesterasi 4
AU2904300A (en) *	1999-01-15	2000-08-01	Byk Gulden Lomberg Chemische Fabrik Gmbh	Polysubstituted 6-phenylphenanthridines with pde-iv inhibiting activity
ATE447952T1 (de)	1999-08-21	2009-11-15	Nycomed Gmbh	Synergistische kombination von pumafentrine und salmeterol
CA2517487A1 (en)	2003-04-01	2004-10-14	Applied Research Systems Ars Holding N.V.	Inhibitors of phosphodiesterases in infertility
US20100086547A1 (en) *	2007-04-30	2010-04-08	Smithkline Beecham Corporation	Methods for administering anti-il-5 antibodies
EP2274009B1 (en)	2008-03-28	2013-11-13	GlaxoSmithKline LLC	Methods of treatment
KR20110071014A (ko)	2008-10-17	2011-06-27	위스콘신 얼럼나이 리서어치 화운데이션	생물학적으로 활성인 알파-베타 펩티드의 제조 방법
JP7295038B2 (ja)	2017-06-06	2023-06-20	グラクソスミスクラインエルエルシー	小児患者のための生物薬剤組成物及び方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB645139A (en) *	1946-10-22	1950-10-25	Servita Gyogyszeryar Es Vegyip	Improved process for the production of isoquinoline derivatives
DE1184344B (de) *	1962-06-16	1964-12-31	Orgamol Sa	Verfahren zur Herstellung von Isochinolinderivaten
US3878215A (en) *	1971-12-01	1975-04-15	Sandoz Ag	2-Alkyl-3-substituted-4-aryl isoquinolines
DE2401453A1 (de) *	1973-01-16	1974-07-18	John James Voorhees	Pharmazeutische zusammensetzung zur behandlung von hautproliferationserkrankungen
US4018927A (en) *	1973-12-17	1977-04-19	The Regents Of The University Of Michigan	Treatment of proliferating skin diseases with papaverine alkaloids
DE2503156A1 (de) *	1974-02-05	1975-08-07	Sandoz Ag	Verfahren zur herstellung neuer heterocyclischer verbindungen
DE2811361A1 (de) *	1978-03-16	1979-09-27	Hoechst Ag	Neue isochinolinaldehyde und verfahren zu ihrer herstellung
DE3244594A1 (de) *	1982-12-02	1984-06-07	Hoechst Ag, 6230 Frankfurt	1-phenylisochinolinderivate und verfahren zu ihrer herstellung, diese verbindung enthaltende pharmazeutische praeparate und deren anwendung
HU196758B (en) *	1986-05-21	1989-01-30	Gyogyszerkutato Intezet	Process for production of 3-hidroxi-methil-quinolines and medical compositions containing them
PH25651A (en) *	1986-05-21	1991-08-21	Duphar Int Res	New di, tetrahydroisoquinoline derivatives

1988
- 1988-01-08 GB GB888800397A patent/GB8800397D0/en active Pending
1989
- 1989-01-03 HU HU8911A patent/HU205083B/hu not_active IP Right Cessation
- 1989-01-04 IT IT8947504A patent/IT1229523B/it active
- 1989-01-04 GB GB8900102A patent/GB2213482B/en not_active Expired - Lifetime
- 1989-01-05 CA CA000587599A patent/CA1332944C/en not_active Expired - Fee Related
- 1989-01-05 DE DE3900233A patent/DE3900233C2/de not_active Expired - Fee Related
- 1989-01-05 ES ES8900053A patent/ES2010071A6/es not_active Expired
- 1989-01-05 SE SE8900039A patent/SE501548C2/sv unknown
- 1989-01-06 FI FI890072A patent/FI90865C/fi not_active IP Right Cessation
- 1989-01-06 ZA ZA89133A patent/ZA89133B/xx unknown
- 1989-01-06 BE BE8900018A patent/BE1002730A3/fr not_active IP Right Cessation
- 1989-01-06 AU AU27795/89A patent/AU622429B2/en not_active Ceased
- 1989-01-06 NL NL8900029A patent/NL8900029A/nl not_active Application Discontinuation
- 1989-01-06 IL IL8889989A patent/IL88899A/en not_active IP Right Cessation
- 1989-01-06 FR FR898900128A patent/FR2625743B1/fr not_active Expired - Lifetime
- 1989-01-06 LU LU87423A patent/LU87423A1/fr unknown
- 1989-01-06 NZ NZ227561A patent/NZ227561A/xx unknown
- 1989-01-06 PL PL1989277092A patent/PL156099B1/pl unknown
- 1989-01-06 PT PT89405A patent/PT89405B/pt not_active IP Right Cessation
- 1989-01-06 PH PH38011A patent/PH25640A/en unknown
- 1989-01-06 DK DK005789A patent/DK5789A/da not_active Application Discontinuation
- 1989-01-06 IE IE3789A patent/IE61914B1/en not_active IP Right Cessation
- 1989-01-06 MY MYPI89000013A patent/MY103963A/en unknown
- 1989-01-06 JP JP1001898A patent/JPH0649686B2/ja not_active Expired - Lifetime
- 1989-01-07 KR KR1019890000151A patent/KR0142686B1/ko not_active IP Right Cessation
- 1989-01-09 GR GR890100008A patent/GR1002750B/el unknown
- 1989-01-09 AT AT0003589A patent/AT394365B/de not_active IP Right Cessation
- 1989-01-09 CH CH59/89A patent/CH678727A5/de not_active IP Right Cessation
1990
- 1990-04-10 US US07/507,702 patent/US4980359A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
GB2213482B (en)	1991-09-11
HU205083B (en)	1992-03-30
FI890072A0 (fi)	1989-01-06
AT394365B (de)	1992-03-25
IT1229523B (it)	1991-09-04
ES2010071A6 (es)	1989-10-16
SE8900039L (sv)	1989-07-09
GB8800397D0 (en)	1988-02-10
ZA89133B (en)	1990-09-26
IL88899A0 (en)	1989-08-15
DE3900233C2 (de)	2000-04-27
HUT52061A (en)	1990-06-28
ATA3589A (de)	1991-09-15
JPH01213267A (ja)	1989-08-28
JPH0649686B2 (ja)	1994-06-29
MY103963A (en)	1993-10-30
AU2779589A (en)	1989-07-20
AU622429B2 (en)	1992-04-09
DE3900233A1 (de)	1989-07-20
US4980359A (en)	1990-12-25
IE890037L (en)	1989-07-08
FI90865B (fi)	1993-12-31
GR890100008A (el)	1994-03-31
CH678727A5 (pt)	1991-10-31
GR1002750B (el)	1997-08-26
DK5789D0 (da)	1989-01-06
FI890072A (fi)	1989-07-09
FI90865C (fi)	1994-04-11
NL8900029A (nl)	1989-08-01
BE1002730A3 (fr)	1991-05-21
CA1332944C (en)	1994-11-08
PT89405B (pt)	1993-09-30
PT89405A (pt)	1990-02-08
GB8900102D0 (en)	1989-03-01
LU87423A1 (fr)	1989-08-30
PL156099B1 (pl)	1992-02-28
GB2213482A (en)	1989-08-16
FR2625743B1 (fr)	1990-11-09
NZ227561A (en)	1991-11-26
SE501548C2 (sv)	1995-03-13
DK5789A (da)	1989-07-09
IT8947504A0 (it)	1989-01-04
KR0142686B1 (ko)	1998-07-15
PH25640A (en)	1991-08-21
SE8900039D0 (sv)	1989-01-05
FR2625743A1 (fr)	1989-07-13
KR890011851A (ko)	1989-08-22
PL277092A1 (en)	1989-09-04
IE61914B1 (en)	1994-11-30

Publication	Publication Date	Title
CA1332944C (en)	1994-11-08	Isoquinoline derivatives, their preparation and their use
US5177085A (en)	1993-01-05	Dihydro-isoquinoline derivatives, processes for their production, pharmaceutical compositions containing them, and their use in treating asthma
EP0258191B1 (en)	1992-05-27	Xanthine derivatives
US5747506A (en)	1998-05-05	Isoquinoline compounds, compositions containing them and their pharmaceutical uses
EP0828733B1 (en)	2001-09-05	Benzopyrans and pharmaceutical compositions containing them
SU1395140A3 (ru)	1988-05-07	Способ получени карбостирильных производных
US5175290A (en)	1992-12-29	8-(oxo-substituted cycloalkyl)xanthines
US4181657A (en)	1980-01-01	2-Aminooctahydroindolo[2,3-a]quinolizines useful in treating cardiovascular disorders
AU599981B2 (en)	1990-08-02	Novel pharmaceutical compositions comprising and use of cis- 6-(4-acetanilido)-8,9-dimethoxy-2-methyl-1,2,3,4,4a,-10b- hexanhydro-benzo{c}{1,6}naphthyridine
EP0435235A1 (en)	1991-07-03	Isoquinoline derivatives and salts thereof as protease inhibitors.
US5281605A (en)	1994-01-25	Novel xanthine derivatives
WO1988005775A1 (en)	1988-08-11	Novel xanthine derivatives
JPH02255678A (ja)	1990-10-16	ピリダジノン誘導体及びその製造方法
NO178430B (no)	1995-12-18	Nye dihydroisokinolinderivater og deres anvendelse som terapeutikum

Legal Events

Date	Code	Title
1997-11-20	HC	Change of name of proprietor(s)
1999-06-20	KB	Patent renewed
2003-10-31	RH1	Patent not in force