IL75987A - Tri-and tetrasubstituted-1,4-dihydro-1,6-naphthyridine-3-carboxylic acid derivatives,their preparation and pharmaceutical compositions containing them - Google Patents

Tri-and tetrasubstituted-1,4-dihydro-1,6-naphthyridine-3-carboxylic acid derivatives,their preparation and pharmaceutical compositions containing them

Info

Publication number: IL75987A
Authority: IL; Israel
Prior art keywords: chained; straight; naphthyridine; carbon atoms; tetrasubstituted
Prior art date: 1984-08-25

Application number

IL8575987Q

Other languages

English (en)

Original Assignee

Goedecke Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-08-25

Filing date

1985-07-31

Publication date

1991-07-18

1984-08-25 Priority claimed from DE19843431303 external-priority patent/DE3431303A1/de

1985-01-29 Priority claimed from DE19853502790 external-priority patent/DE3502790A1/de

1985-07-31 Application filed by Goedecke Ag filed Critical Goedecke Ag

1991-07-18 Publication of IL75987A publication Critical patent/IL75987A/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
- C07D213/80—Acids; Esters in position 3
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)
Hydrogenated Pyridines (AREA)
Liquid Crystal Substances (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

IL8575987Q 1984-08-25 1985-07-31 Tri-and tetrasubstituted-1,4-dihydro-1,6-naphthyridine-3-carboxylic acid derivatives,their preparation and pharmaceutical compositions containing them IL75987A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE19843431303 DE3431303A1 (de)	1984-08-25	1984-08-25	1,6-naphthyridin-derivate, verfahren zu deren herstellung und deren verwendung
DE19853502790 DE3502790A1 (de)	1985-01-29	1985-01-29	1,6-naphthyridin-derivate, verfahren zu deren herstellung und deren verwendung

Publications (1)

Publication Number	Publication Date
IL75987A true IL75987A (en)	1991-07-18

Family

ID=25824189

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
IL8575987Q IL75987A (en)	1984-08-25	1985-07-31	Tri-and tetrasubstituted-1,4-dihydro-1,6-naphthyridine-3-carboxylic acid derivatives,their preparation and pharmaceutical compositions containing them
IL75987A IL75987A0 (en)	1984-08-25	1985-08-01	1,6-naphthyridine derivatives,their preparation and pharmaceutical compositions containing them

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
IL75987A IL75987A0 (en)	1984-08-25	1985-08-01	1,6-naphthyridine derivatives,their preparation and pharmaceutical compositions containing them

Country Status (22)

Country	Link
US (1)	US4711901A (el)
EP (1)	EP0173933B1 (el)
KR (1)	KR890000706B1 (el)
AT (1)	ATE48276T1 (el)
AU (1)	AU576887B2 (el)
BG (1)	BG43691A3 (el)
CA (1)	CA1263118A (el)
DE (1)	DE3574471D1 (el)
DK (1)	DK165247C (el)
ES (1)	ES8604960A1 (el)
FI (1)	FI80697C (el)
GR (1)	GR852040B (el)
HU (1)	HU194879B (el)
IE (1)	IE58364B1 (el)
IL (2)	IL75987A (el)
NO (1)	NO161493C (el)
NZ (1)	NZ213218A (el)
PH (4)	PH21177A (el)
PL (1)	PL146668B1 (el)
RO (1)	RO92245B (el)
SU (1)	SU1395143A3 (el)
YU (2)	YU45000B (el)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3431303A1 (de) *	1984-08-25	1986-02-27	Goedecke Ag	1,6-naphthyridin-derivate, verfahren zu deren herstellung und deren verwendung
DE3906406C1 (el) *	1989-03-01	1990-10-25	Goedecke Ag, 1000 Berlin, De
DE3906460C1 (el) *	1989-03-01	1990-11-15	Goedecke Ag, 1000 Berlin, De
DE102006026583A1 (de)	2006-06-07	2007-12-13	Bayer Healthcare Aktiengesellschaft	Aryl-substituierte hetero-bicyclische Verbindungen und ihre Verwendung
DE102006026585A1 (de) *	2006-06-07	2007-12-13	Bayer Healthcare Aktiengesellschaft	Substituierte 4-Aryl-1,4-dihydro-1,6-naphthyridine und ihre Verwendung
DE102007009494A1 (de)	2007-02-27	2008-08-28	Bayer Healthcare Ag	Substituierte 4-Aryl-1, 4-dihydro-1,6-naphthyridinamide und ihre Verwendung
US10059707B2 (en) *	2014-08-01	2018-08-28	Bayer Pharma AG	Method for the preparation of (4S)-4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro- 1-6-naphthyridine-3-carbox-amide and the purification thereof for use as an active pharmaceutical ingredient
EP3337800B1 (de) *	2015-08-21	2019-06-12	Bayer Pharma Aktiengesellschaft	Verfahren zur herstellung von (4s)- 4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridin-3-carboxamid und dessen aufreinigung für die verwendung als pharmazeutischer wirkstoff
JP6843120B2 (ja) *	2015-08-21	2021-03-17	バイエル・ファルマ・アクティエンゲゼルシャフト	（４ｓ）−４−（４−シアノ−２−メトキシフェニル）−５−エトキシ−２，８−ジメチル−１，４−ジヒドロ−１，６−ナフチリジン−３−カルボキサミドの調製方法および電気化学的方法による（４ｓ）−４−（４−シアノ−２−メトキシフェニル）−５−エトキシ−２，８−ジメチル−１，４−ジヒドロ−１，６−ナフチリジン−３−カルボキサミドの回収

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4304914A (en) *	1980-07-07	1981-12-08	Usv Pharmaceutical Corporation	Naphthyridone derivatives
DE3327650A1 (de) *	1983-07-30	1985-02-14	Gödecke AG, 1000 Berlin	1,6-naphthyridinon-derivate, verfahren zu deren herstellung und deren verwendung bei der bekaempfung von gefaesserkrankungen

1985
- 1985-07-31 IL IL8575987Q patent/IL75987A/xx not_active IP Right Cessation
- 1985-08-01 IL IL75987A patent/IL75987A0/xx not_active IP Right Cessation
- 1985-08-15 SU SU853936405A patent/SU1395143A3/ru active
- 1985-08-21 BG BG071530A patent/BG43691A3/xx unknown
- 1985-08-21 RO RO119914A patent/RO92245B/ro unknown
- 1985-08-22 FI FI853233A patent/FI80697C/fi not_active IP Right Cessation
- 1985-08-22 GR GR852040A patent/GR852040B/el unknown
- 1985-08-23 CA CA000489290A patent/CA1263118A/en not_active Expired
- 1985-08-23 AT AT85110646T patent/ATE48276T1/de not_active IP Right Cessation
- 1985-08-23 HU HU853212A patent/HU194879B/hu not_active IP Right Cessation
- 1985-08-23 PH PH32684A patent/PH21177A/en unknown
- 1985-08-23 IE IE208585A patent/IE58364B1/en not_active IP Right Cessation
- 1985-08-23 ES ES546366A patent/ES8604960A1/es not_active Expired
- 1985-08-23 DK DK384485A patent/DK165247C/da not_active IP Right Cessation
- 1985-08-23 NO NO853329A patent/NO161493C/no unknown
- 1985-08-23 NZ NZ213218A patent/NZ213218A/en unknown
- 1985-08-23 PL PL1985255118A patent/PL146668B1/pl unknown
- 1985-08-23 DE DE8585110646T patent/DE3574471D1/de not_active Expired - Fee Related
- 1985-08-23 EP EP85110646A patent/EP0173933B1/de not_active Expired
- 1985-08-23 AU AU46626/85A patent/AU576887B2/en not_active Ceased
- 1985-08-23 YU YU1348/85A patent/YU45000B/xx unknown
- 1985-08-24 KR KR1019850006133A patent/KR890000706B1/ko not_active IP Right Cessation
1986
- 1986-07-30 US US06/891,712 patent/US4711901A/en not_active Expired - Lifetime
- 1986-10-03 PH PH34327A patent/PH23411A/en unknown
- 1986-10-03 PH PH34326A patent/PH23379A/en unknown
1987
- 1987-06-17 PH PH35419A patent/PH24762A/en unknown
1988
- 1988-01-26 YU YU14588A patent/YU47010B/sh unknown

Also Published As

Publication number	Publication date
HUT39448A (en)	1986-09-29
RO92245B (ro)	1987-07-31
NO161493C (no)	1989-08-23
IL75987A0 (en)	1985-12-31
US4711901A (en)	1987-12-08
CA1263118A (en)	1989-11-21
FI853233A0 (fi)	1985-08-22
PH23379A (en)	1989-07-26
PL255118A1 (en)	1986-07-29
IE852085L (en)	1986-02-25
AU4662685A (en)	1986-02-27
KR890000706B1 (ko)	1989-03-27
YU45000B (en)	1991-06-30
EP0173933A1 (de)	1986-03-12
SU1395143A3 (ru)	1988-05-07
AU576887B2 (en)	1988-09-08
NO161493B (no)	1989-05-16
KR860001810A (ko)	1986-03-22
ES546366A0 (es)	1986-03-01
RO92245A (ro)	1987-07-30
YU14588A (en)	1991-02-28
PL146668B1 (en)	1989-02-28
PH21177A (en)	1987-08-07
HU194879B (en)	1988-03-28
DK384485D0 (da)	1985-08-23
FI80697C (fi)	1990-07-10
YU134885A (en)	1988-10-31
DE3574471D1 (de)	1990-01-04
DK165247B (da)	1992-10-26
YU47010B (sh)	1994-11-15
DK165247C (da)	1993-04-26
FI853233L (fi)	1986-02-26
PH23411A (en)	1989-07-26
ATE48276T1 (de)	1989-12-15
GR852040B (el)	1985-12-19
FI80697B (fi)	1990-03-30
PH24762A (en)	1990-10-01
NZ213218A (en)	1990-01-29
EP0173933B1 (de)	1989-11-29
DK384485A (da)	1986-02-26
NO853329L (no)	1986-02-26
IE58364B1 (en)	1993-09-08
BG43691A3 (en)	1988-07-15
ES8604960A1 (es)	1986-03-01

Publication	Publication Date	Title
ES8705371A1 (es)	1987-05-16	Procedimiento para preparar derivados de amino-propanol
IL75987A (en)	1991-07-18	Tri-and tetrasubstituted-1,4-dihydro-1,6-naphthyridine-3-carboxylic acid derivatives,their preparation and pharmaceutical compositions containing them
NO852514L (no)	1985-12-23	Analogifremgangsmaate for fremstilling av terapeutisk aktive 8-alkyltio-2-piperazino-pyrimido (5,4-d) pyrimidin-derivater.
AU6690190A (en)	1991-05-30	New thiophene derivatives, the process for the preparation thereof and the pharmaceutical compositions containing them
DE3787844D1 (de)	1993-11-25	Thioester und dessen Verwendung zur Herstellung von pharmazeutischen Zusammensetzungen zur Behandlung von Ischämie und von Reperfusion-Syndromen.
HU895522D0 (en)	1990-09-28	Process for the preparation of new thienyl-oxy-alkyl-amine derivatives and pharmaceutical compositions containing them
EP0239500A3 (en)	1988-07-27	1-styrene-sulfonyl-2-oxo-5-hydroxy-pyrrolidine derivatives, their intermediates, process for their preparation, compositions containing them and their use as medicines
HU904214D0 (en)	1990-12-28	Process for producing pyrrolo(2,1-b)thiazole derivatives
JPS6422852A (en)	1989-01-25	Novel derivative of 1-arylsulfonyl-1,5-dihydro- 2h-pyrrole-2-one, manufacture and intermediate, use as drug and composition
ZA872925B (en)	1987-11-25	Heterocyclic compounds
JPS6426553A (en)	1989-01-27	Novel derivative of 1-benzyl-2-oxo-5-alkoxy- pyrrolidine, manufacture, use as drug and composition

Legal Events

Date	Code	Title	Description
1996-05-14	RH	Patent void