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IL71788A - 6-phenyl-3(2h)pyridazinones(thiones),processes for their preparation and pharmaceutical compositions containing the same - Google Patents

6-phenyl-3(2h)pyridazinones(thiones),processes for their preparation and pharmaceutical compositions containing the same

Info

Publication number
IL71788A
IL71788A IL71788A IL7178884A IL71788A IL 71788 A IL71788 A IL 71788A IL 71788 A IL71788 A IL 71788A IL 7178884 A IL7178884 A IL 7178884A IL 71788 A IL71788 A IL 71788A
Authority
IL
Israel
Prior art keywords
pyridazinones
pct
processes
preparation
thiones
Prior art date
Application number
IL71788A
Other languages
English (en)
Other versions
IL71788A0 (en
Original Assignee
Byk Gulden Lomberg Chem Fab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Byk Gulden Lomberg Chem Fab filed Critical Byk Gulden Lomberg Chem Fab
Publication of IL71788A0 publication Critical patent/IL71788A0/xx
Publication of IL71788A publication Critical patent/IL71788A/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50Pyridazines; Hydrogenated pyridazines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D237/00Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/14Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D237/00Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/18Sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)
IL71788A 1983-05-11 1984-05-10 6-phenyl-3(2h)pyridazinones(thiones),processes for their preparation and pharmaceutical compositions containing the same IL71788A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH258183 1983-05-11

Publications (2)

Publication Number Publication Date
IL71788A0 IL71788A0 (en) 1984-09-30
IL71788A true IL71788A (en) 1987-09-16

Family

ID=4237009

Family Applications (1)

Application Number Title Priority Date Filing Date
IL71788A IL71788A (en) 1983-05-11 1984-05-10 6-phenyl-3(2h)pyridazinones(thiones),processes for their preparation and pharmaceutical compositions containing the same

Country Status (15)

Country Link
US (1) US4707481A (xx)
EP (1) EP0125636B1 (xx)
JP (1) JPS60501258A (xx)
AT (1) ATE26266T1 (xx)
AU (1) AU560607B2 (xx)
CA (1) CA1247100A (xx)
DE (2) DE3417391A1 (xx)
DK (1) DK156655C (xx)
ES (1) ES532337A0 (xx)
GR (1) GR82072B (xx)
IL (1) IL71788A (xx)
NZ (1) NZ208107A (xx)
PT (1) PT78566B (xx)
WO (1) WO1984004521A1 (xx)
ZA (1) ZA843520B (xx)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK159431C (da) * 1984-05-10 1991-03-18 Byk Gulden Lomberg Chem Fab 6-phenyl-3(2h)-pyridazinoner, fremgangsmaade til fremstilling deraf, laegemidler indeholdende disse samt anvendelse af forbindelserne til fremstilling af laegemidler
IL79280A (en) * 1985-07-05 1990-07-12 Smith Kline French Lab 4-(6-oxo-dihydro or tetrahydropyridazin-3-yl)benzene derivatives,their preparation and pharmaceutical compositions containing them
DE3827362A1 (de) * 1988-08-12 1990-02-15 Basf Ag Pulvrige, hydrophile theophyllinformulierung und verfahren zur ihrer herstellung
ES2075202T3 (es) * 1989-04-17 1995-10-01 Byk Gulden Lomberg Chem Fab Nuevas arilpiridazinas, su preparacion, su utilizacion, y medicamentos que las contienen.
DE59109027D1 (en) * 1990-10-16 1998-08-13 Byk Gulden Lomberg Chem Fab Arylpyridazinone
EP0581805A1 (de) * 1991-04-26 1994-02-09 Byk Gulden Lomberg Chemische Fabrik Gmbh Neue pyridazine
DE59207016D1 (de) 1991-07-05 1996-10-02 Byk Gulden Lomberg Chem Fab Verwendung substituierter pyridazine gegen dermatosen
US5814651A (en) * 1992-12-02 1998-09-29 Pfizer Inc. Catechol diethers as selective PDEIV inhibitors
CA2400368A1 (en) * 1992-12-02 1994-06-09 Allen J. Duplantier Catechol diethers as selective pde iv inhibitors
DE19514568A1 (de) * 1995-04-20 1996-10-24 Merck Patent Gmbh Arylalkyl-pyridazinone
CA2276429C (en) * 1997-02-17 2007-06-19 Byk Gulden Lomberg Chemische Fabrik Gmbh Compositions for the treatment of ards or irds containing 3-(cyclopropylmethoxy)-n-(3,5-dichloro-4-pyridinyl)-4-(difluoromethoxy)benzamide and lung surfactant
US7437192B2 (en) * 2005-04-05 2008-10-14 Pacesetter, Inc. System and method for detecting heart failure and pulmonary edema based on ventricular end-diastolic pressure using an implantable medical device
CN101668732A (zh) * 2007-04-02 2010-03-10 同一世界健康研究院 Cftr抑制剂化合物及其用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT343125B (de) * 1976-03-24 1978-05-10 Chemie Linz Ag Verfahren zur herstellung von 3-phenylpyridazon- (6)
JPS6037101B2 (ja) * 1977-03-09 1985-08-24 三共株式会社 フエニルピリダジノン誘導体の製法
US4397854A (en) * 1981-05-14 1983-08-09 Warner-Lambert Company Substituted 6-phenyl-3(2H)-pyridazinones useful as cardiotonic agents
JPS588015A (ja) * 1981-07-06 1983-01-18 Mitsubishi Chem Ind Ltd 強心剤

Also Published As

Publication number Publication date
CA1247100A (en) 1988-12-20
IL71788A0 (en) 1984-09-30
ZA843520B (en) 1984-12-24
GR82072B (xx) 1984-12-13
DE3417391A1 (de) 1984-11-15
DK12485D0 (da) 1985-01-10
EP0125636B1 (de) 1987-04-01
DK156655C (da) 1990-02-05
ATE26266T1 (de) 1987-04-15
EP0125636A1 (de) 1984-11-21
DK156655B (da) 1989-09-18
NZ208107A (en) 1986-12-05
US4707481A (en) 1987-11-17
ES8601918A1 (es) 1985-12-01
WO1984004521A1 (en) 1984-11-22
JPS60501258A (ja) 1985-08-08
DK12485A (da) 1985-01-10
PT78566B (de) 1986-07-17
PT78566A (de) 1984-06-01
AU560607B2 (en) 1987-04-09
ES532337A0 (es) 1985-12-01
AU2961784A (en) 1984-12-04
DE3462890D1 (en) 1987-05-07

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