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IL68793A - 1-(substituted alkyl)(homo)-piperazin-4-yl imidazopyridine and pyridopyrazine derivatives,their production and pharmaceutical compositions containing them - Google Patents

1-(substituted alkyl)(homo)-piperazin-4-yl imidazopyridine and pyridopyrazine derivatives,their production and pharmaceutical compositions containing them

Info

Publication number
IL68793A
IL68793A IL68793A IL6879383A IL68793A IL 68793 A IL68793 A IL 68793A IL 68793 A IL68793 A IL 68793A IL 6879383 A IL6879383 A IL 6879383A IL 68793 A IL68793 A IL 68793A
Authority
IL
Israel
Prior art keywords
imidazopyridine
piperazin
homo
production
pharmaceutical compositions
Prior art date
Application number
IL68793A
Other languages
English (en)
Other versions
IL68793A0 (en
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of IL68793A0 publication Critical patent/IL68793A0/xx
Publication of IL68793A publication Critical patent/IL68793A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/74Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/75Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL68793A 1982-05-28 1983-05-26 1-(substituted alkyl)(homo)-piperazin-4-yl imidazopyridine and pyridopyrazine derivatives,their production and pharmaceutical compositions containing them IL68793A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
CH331782 1982-05-28
CH337982 1982-06-02
CH448582 1982-07-22
CH448482 1982-07-22

Publications (2)

Publication Number Publication Date
IL68793A0 IL68793A0 (en) 1983-09-30
IL68793A true IL68793A (en) 1987-03-31

Family

ID=27428609

Family Applications (1)

Application Number Title Priority Date Filing Date
IL68793A IL68793A (en) 1982-05-28 1983-05-26 1-(substituted alkyl)(homo)-piperazin-4-yl imidazopyridine and pyridopyrazine derivatives,their production and pharmaceutical compositions containing them

Country Status (18)

Country Link
US (2) US4565816A (xx)
AU (1) AU573524B2 (xx)
CA (1) CA1203801A (xx)
DE (1) DE3318671A1 (xx)
DK (1) DK237383A (xx)
ES (1) ES522786A0 (xx)
FI (1) FI73999C (xx)
FR (2) FR2527608B1 (xx)
GB (1) GB2120670B (xx)
HU (1) HU191844B (xx)
IE (1) IE55312B1 (xx)
IL (1) IL68793A (xx)
NL (1) NL8301844A (xx)
NZ (1) NZ204369A (xx)
PH (1) PH22871A (xx)
PT (1) PT76768B (xx)
SE (1) SE452766B (xx)
WO (1) WO1983004254A1 (xx)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4803203A (en) * 1986-11-05 1989-02-07 Warner-Lambert Company Phenyl and heterocyclic piperazinyl alkoxy-benzheterocyclic compounds as antipsychotic agents
US5502187A (en) * 1992-04-03 1996-03-26 The Upjohn Company Pharmaceutically active bicyclic-heterocyclic amines
US6432957B1 (en) * 2001-06-29 2002-08-13 Kowa Co., Ltd. Piperazine derivative
GB0215293D0 (en) * 2002-07-03 2002-08-14 Rega Foundation Viral inhibitors
JP4970048B2 (ja) * 2003-12-22 2012-07-04 カトリーケ・ウニフェルジテイト・ルーベン・カー・イュー・ルーベン・アール・アンド・ディ イミダゾ[4,5−c]ピリジン化合物および抗ウイルス治療の方法
NZ556624A (en) * 2004-12-21 2010-06-25 Gilead Sciences Inc 5-((3-(2,4-trifluoromethyphenyl)isoxazol-5-yl)methyl)-2-(2-fluorophenyl)-5H-imidazo[4,5-c]pyridine and method of antiviral treatment
US7582636B2 (en) * 2005-05-26 2009-09-01 Wyeth Piperazinylimidazopyridine and piperazinyltriazolopyridine antagonists of Gonadotropin Releasing Hormone receptor
ATE454384T1 (de) * 2006-07-07 2010-01-15 Gilead Sciences Inc Neue pyridazinverbindung und ihre verwendung
UA99466C2 (xx) 2007-07-06 2012-08-27 Гилиад Сайенсиз, Инк. Кристалічна сполука піридазину$кристаллическое соединение пиридазина
NZ703111A (en) * 2010-05-17 2016-07-29 Incozen Therapeutics Pvt Ltd Novel 3,5-disubstitued-3h-imidazo[4,5-b]pyridine and 3,5- disubstitued -3h-[1,2,3]triazolo[4,5-b] pyridine compounds as modulators of protein kinases
CN102952121A (zh) * 2012-07-27 2013-03-06 北京海步国际医药科技发展有限公司 一种哌嗪衍生物的一种改进的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL129219C (xx) * 1965-12-16
GB1165283A (en) * 1967-01-17 1969-09-24 Science Union & Cie New Purine Derivatives and processes for prepararing them
US4022779A (en) * 1974-07-25 1977-05-10 E. R. Squibb & Sons, Inc. Amino derivatives of pyrido(3,4-b)pyrazine carboxylic acids and esters
US4082845A (en) * 1977-04-25 1978-04-04 Merck & Co., Inc. 3-(1-Piperazinyl)-pyrido[2,3-b]pyrazines

Also Published As

Publication number Publication date
FR2536398A1 (fr) 1984-05-25
FR2527608B1 (fr) 1986-10-10
CA1203801A (en) 1986-04-29
DK237383A (da) 1983-11-29
FI73999C (fi) 1987-12-10
FI73999B (fi) 1987-08-31
HU191844B (en) 1987-04-28
NZ204369A (en) 1986-09-10
PH22871A (en) 1989-01-19
PT76768A (fr) 1983-06-01
IL68793A0 (en) 1983-09-30
AU1501283A (en) 1983-12-01
GB2120670B (en) 1985-11-27
IE831263L (en) 1983-11-28
WO1983004254A1 (en) 1983-12-08
NL8301844A (nl) 1983-12-16
SE8302979L (sv) 1983-11-29
FI831790A0 (fi) 1983-05-20
AU573524B2 (en) 1988-06-16
FI831790L (fi) 1983-11-29
IE55312B1 (en) 1990-08-01
US4652565A (en) 1987-03-24
ES8502988A1 (es) 1985-02-01
DK237383D0 (da) 1983-05-26
ES522786A0 (es) 1985-02-01
US4565816A (en) 1986-01-21
FR2536398B1 (fr) 1986-12-05
SE8302979D0 (sv) 1983-05-26
SE452766B (sv) 1987-12-14
PT76768B (fr) 1986-01-28
DE3318671A1 (de) 1983-12-01
GB2120670A (en) 1983-12-07
GB8314456D0 (en) 1983-06-29
FR2527608A1 (fr) 1983-12-02

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