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IL42385A - N-substituted prostaglandin carbox-amides and their preparation - Google Patents

N-substituted prostaglandin carbox-amides and their preparation

Info

Publication number
IL42385A
IL42385A IL42385A IL4238573A IL42385A IL 42385 A IL42385 A IL 42385A IL 42385 A IL42385 A IL 42385A IL 4238573 A IL4238573 A IL 4238573A IL 42385 A IL42385 A IL 42385A
Authority
IL
Israel
Prior art keywords
carbox
amides
preparation
substituted prostaglandin
prostaglandin
Prior art date
Application number
IL42385A
Other versions
IL42385A0 (en
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of IL42385A0 publication Critical patent/IL42385A0/en
Publication of IL42385A publication Critical patent/IL42385A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0041Analogues having the carboxyl group in the side-chains replaced by other functional groups containing nitrogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D309/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10Oxygen atoms
    • C07D309/12Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/30Hetero atoms other than halogen
    • C07D333/34Sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40Esters thereof
    • C07F9/4003Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4006Esters of acyclic acids which can have further substituents on alkyl
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/54Quaternary phosphonium compounds
    • C07F9/5407Acyclic saturated phosphonium compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
  • Pyrane Compounds (AREA)
IL42385A 1972-06-07 1973-05-29 N-substituted prostaglandin carbox-amides and their preparation IL42385A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US26051872A 1972-06-07 1972-06-07

Publications (2)

Publication Number Publication Date
IL42385A0 IL42385A0 (en) 1973-07-30
IL42385A true IL42385A (en) 1979-10-31

Family

ID=22989486

Family Applications (2)

Application Number Title Priority Date Filing Date
IL42385A IL42385A (en) 1972-06-07 1973-05-29 N-substituted prostaglandin carbox-amides and their preparation
IL51525A IL51525A0 (en) 1972-06-07 1977-02-23 New triphenylphosphonium compounds and their preparation

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL51525A IL51525A0 (en) 1972-06-07 1977-02-23 New triphenylphosphonium compounds and their preparation

Country Status (24)

Country Link
JP (2) JPS5715591B2 (en)
AR (1) AR207434A1 (en)
AT (1) AT340069B (en)
BE (1) BE800580A (en)
CA (1) CA985280A (en)
CH (3) CH591511A5 (en)
CS (1) CS200166B2 (en)
DD (2) DD115687A5 (en)
DE (1) DE2329092A1 (en)
ES (3) ES415611A1 (en)
FI (1) FI58327C (en)
FR (2) FR2187344B1 (en)
GB (2) GB1439511A (en)
HU (3) HU170491B (en)
IE (1) IE38058B1 (en)
IL (2) IL42385A (en)
IN (1) IN138966B (en)
LU (1) LU67754A1 (en)
NL (2) NL160814C (en)
NO (2) NO146538C (en)
PH (2) PH14204A (en)
SE (3) SE415883B (en)
YU (1) YU36498B (en)
ZA (1) ZA733763B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX3291E (en) * 1975-04-23 1980-08-22 Upjohn Co PROCEDURE FOR PREPARING ANALOGS OF PROSTAGLANDINAS
US6395787B1 (en) * 2000-02-08 2002-05-28 Allergan Sales, Inc. Ocular hypotensive lipids
US6476064B1 (en) * 2001-06-13 2002-11-05 Allergan, Inc. Cyclopentane heptan(ene) acyl sulfonamide, 2-alkyl or 2-arylalkyl, or 2-heteroarylalkenyl derivatives as therapeutic agents

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3187043A (en) * 1962-05-18 1965-06-01 Monsanto Co Monohalophosphonium halides

Also Published As

Publication number Publication date
JPS4954350A (en) 1974-05-27
FR2187344B1 (en) 1977-10-28
IL42385A0 (en) 1973-07-30
NL7812163A (en) 1979-04-27
HU170491B (en) 1977-06-28
CH605887A5 (en) 1978-10-13
SE7608225L (en) 1976-07-19
LU67754A1 (en) 1973-12-14
FR2187344A1 (en) 1974-01-18
ES430416A1 (en) 1976-10-16
YU36498B (en) 1984-02-29
NL7307867A (en) 1973-12-11
IE38058B1 (en) 1977-12-21
IE38058L (en) 1973-12-07
PH13092A (en) 1979-11-27
CH593929A5 (en) 1977-12-30
HU170200B (en) 1977-04-28
HU170487B (en) 1977-06-28
GB1439512A (en) 1976-06-16
NL160814C (en) 1979-12-17
NO142784C (en) 1980-10-15
ATA504873A (en) 1977-03-15
SE415883B (en) 1980-11-10
NO142784B (en) 1980-07-07
JPS5731692A (en) 1982-02-20
ES415611A1 (en) 1976-07-16
IN138966B (en) 1976-04-17
CA985280A (en) 1976-03-09
YU152673A (en) 1982-02-25
CH591511A5 (en) 1977-09-30
NO740850L (en) 1973-12-10
AU5643173A (en) 1974-12-05
NO146538B (en) 1982-07-12
IL51525A0 (en) 1977-04-29
DE2329092A1 (en) 1974-01-03
AT340069B (en) 1977-11-25
DD115687A5 (en) 1975-10-12
DD109211A5 (en) 1974-10-20
BE800580A (en) 1973-12-07
AR207434A1 (en) 1976-10-08
FI58327B (en) 1980-09-30
ES430417A1 (en) 1977-03-01
NO146538C (en) 1982-10-20
NL160814B (en) 1979-07-16
FI58327C (en) 1981-01-12
SE418744B (en) 1981-06-22
GB1439511A (en) 1976-06-16
CS200166B2 (en) 1980-08-29
FR2273814A1 (en) 1976-01-02
ZA733763B (en) 1974-04-24
SE7608224L (en) 1976-07-19
JPS5715591B2 (en) 1982-03-31
FR2273814B1 (en) 1977-07-08
PH14204A (en) 1981-04-01

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