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IL40250A0 - 3,4-dihydro-2h-isoquinoline-1-thiones and process for preparing them - Google Patents

3,4-dihydro-2h-isoquinoline-1-thiones and process for preparing them

Info

Publication number
IL40250A0
IL40250A0 IL40250A IL4025072A IL40250A0 IL 40250 A0 IL40250 A0 IL 40250A0 IL 40250 A IL40250 A IL 40250A IL 4025072 A IL4025072 A IL 4025072A IL 40250 A0 IL40250 A0 IL 40250A0
Authority
IL
Israel
Prior art keywords
thiones
isoquinoline
dihydro
preparing
Prior art date
Application number
IL40250A
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of IL40250A0 publication Critical patent/IL40250A0/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D221/00Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/20Spiro-condensed ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/24Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/50Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/58Radicals substituted by nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
IL40250A 1971-09-01 1972-08-29 3,4-dihydro-2h-isoquinoline-1-thiones and process for preparing them IL40250A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2143745A DE2143745A1 (en) 1971-09-01 1971-09-01 3,4-DIHYDRO-2H-ISOCHINOLIN-1-THIONE AND THE METHOD FOR MANUFACTURING IT

Publications (1)

Publication Number Publication Date
IL40250A0 true IL40250A0 (en) 1972-10-29

Family

ID=5818354

Family Applications (1)

Application Number Title Priority Date Filing Date
IL40250A IL40250A0 (en) 1971-09-01 1972-08-29 3,4-dihydro-2h-isoquinoline-1-thiones and process for preparing them

Country Status (11)

Country Link
JP (1) JPS4834885A (en)
AU (1) AU4610472A (en)
BE (1) BE788321A (en)
CA (1) CA972755A (en)
DD (1) DD102148A5 (en)
DE (1) DE2143745A1 (en)
ES (1) ES406134A1 (en)
FR (1) FR2151044A1 (en)
IL (1) IL40250A0 (en)
NL (1) NL7211627A (en)
ZA (1) ZA725997B (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL89997A0 (en) * 1988-04-25 1989-12-15 Lilly Co Eli Propanamine derivatives
US5177075A (en) * 1988-08-19 1993-01-05 Warner-Lambert Company Substituted dihydroisoquinolinones and related compounds as potentiators of the lethal effects of radiation and certain chemotherapeutic agents; selected compounds, analogs and process
EP0355750B1 (en) * 1988-08-19 1995-01-25 Warner-Lambert Company Substituted dihydroisoquinolinones and related compounds as potentiators of the lethal effects of radiation and certain chemotherapeutic agents; selected compounds, analogs and process
US7151102B2 (en) 2000-10-30 2006-12-19 Kudos Pharmaceuticals Limited Phthalazinone derivatives
ATE355278T1 (en) * 2001-05-08 2006-03-15 Kudos Pharm Ltd ISOQUINOLINONE DERIVATIVES AS PARP INHIBITORS
ATE491703T1 (en) 2002-04-30 2011-01-15 Kudos Pharm Ltd PHTHALAZINONE DERIVATIVES
GB0305681D0 (en) 2003-03-12 2003-04-16 Kudos Pharm Ltd Phthalazinone derivatives
US7449464B2 (en) 2003-03-12 2008-11-11 Kudos Pharmaceuticals Limited Phthalazinone derivatives
GB0419072D0 (en) 2004-08-26 2004-09-29 Kudos Pharm Ltd Phthalazinone derivatives
GB0521373D0 (en) 2005-10-20 2005-11-30 Kudos Pharm Ltd Pthalazinone derivatives
AU2008299721A1 (en) 2007-09-14 2009-03-19 Astrazeneca Ab Phthalazinone derivatives
JP5593229B2 (en) 2007-10-17 2014-09-17 クドス ファーマシューティカルズ リミテッド 4- [3- (4-Cyclopropanecarbonyl-piperazine-1-carbonyl) -4-fluoro-benzyl] -2H-phthalazin-1-one
AR070221A1 (en) 2008-01-23 2010-03-25 Astrazeneca Ab DERIVATIVES OF FTALAZINONA POLYMERASE INHIBITORS, PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM AND USES OF THE SAME TO PREVENT AND / OR TREAT CANCERIGENE TUMORS, ISCHEMICAL INJURIES AND OTHER ASSOCIATED DISEASES.
ES2598178T5 (en) 2008-10-07 2023-12-26 Kudos Pharm Ltd Pharmaceutical formulation 514

Also Published As

Publication number Publication date
CA972755A (en) 1975-08-12
ZA725997B (en) 1973-07-25
DD102148A5 (en) 1973-12-05
NL7211627A (en) 1973-03-05
ES406134A1 (en) 1975-08-01
AU4610472A (en) 1974-03-07
JPS4834885A (en) 1973-05-22
BE788321A (en) 1973-03-01
DE2143745A1 (en) 1973-03-08
FR2151044A1 (en) 1973-04-13

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