IL133788A0 - Tricyclic vasopressin agonists - Google Patents
Tricyclic vasopressin agonistsInfo
- Publication number
- IL133788A0 IL133788A0 IL13378898A IL13378898A IL133788A0 IL 133788 A0 IL133788 A0 IL 133788A0 IL 13378898 A IL13378898 A IL 13378898A IL 13378898 A IL13378898 A IL 13378898A IL 133788 A0 IL133788 A0 IL 133788A0
- Authority
- IL
- Israel
- Prior art keywords
- vasopressin agonists
- tricyclic
- tricyclic vasopressin
- agonists
- vasopressin
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/12—Antidiuretics, e.g. drugs for diabetes insipidus
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US90336997A | 1997-07-30 | 1997-07-30 | |
PCT/US1998/015495 WO1999006409A1 (fr) | 1997-07-30 | 1998-07-24 | Agonistes tricycliques de la vasopressine |
Publications (1)
Publication Number | Publication Date |
---|---|
IL133788A0 true IL133788A0 (en) | 2001-04-30 |
Family
ID=25417392
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL13378898A IL133788A0 (en) | 1997-07-30 | 1998-07-24 | Tricyclic vasopressin agonists |
Country Status (22)
Country | Link |
---|---|
EP (1) | EP1000062B1 (fr) |
JP (1) | JP4338305B2 (fr) |
KR (1) | KR100580805B1 (fr) |
CN (1) | CN1183134C (fr) |
AR (1) | AR016557A1 (fr) |
AT (1) | ATE277050T1 (fr) |
AU (1) | AU756959B2 (fr) |
BR (1) | BR9811585A (fr) |
CA (1) | CA2297406C (fr) |
DE (1) | DE69826487T2 (fr) |
DK (1) | DK1000062T3 (fr) |
ES (1) | ES2229525T3 (fr) |
HU (1) | HUP0002480A3 (fr) |
IL (1) | IL133788A0 (fr) |
NO (1) | NO315273B1 (fr) |
NZ (1) | NZ502449A (fr) |
PT (1) | PT1000062E (fr) |
RU (1) | RU2213094C2 (fr) |
SI (1) | SI1000062T1 (fr) |
TW (1) | TW502035B (fr) |
WO (1) | WO1999006409A1 (fr) |
ZA (1) | ZA986784B (fr) |
Families Citing this family (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7138393B2 (en) * | 1998-07-24 | 2006-11-21 | Wyeth | Biologically active vasopressin agonist metabolites |
DK1147115T5 (da) * | 1999-01-19 | 2008-12-08 | Ortho Mcneil Pharm Inc | Tricycliske benzodiazepiner som vasopressinreceptorantagonister |
MXPA02003191A (es) * | 1999-09-27 | 2002-09-30 | American Cyanamid Co | Formulacion agonista de vasopresina y proceso para elaborar la misma. |
US6831079B1 (en) * | 1999-09-27 | 2004-12-14 | American Cyanamid Company | Vasopressin agonist formulation and process |
GB0000079D0 (en) | 2000-01-05 | 2000-02-23 | Ferring Bv | Novel antidiuretic agents |
GB0015601D0 (en) * | 2000-06-26 | 2000-08-16 | Ferring Bv | Novel antidiuretic agents |
US7022699B2 (en) | 2001-04-12 | 2006-04-04 | Wyeth | Cyclohexenyl phenyl diazepines vasopressin and oxytocin receptor modulators |
US6900200B2 (en) | 2001-04-12 | 2005-05-31 | Wyeth | Tricyclic hydroxy carboxamides and derivatives thereof tocolytic oxytocin receptor antagonists |
US7202239B2 (en) | 2001-04-12 | 2007-04-10 | Wyeth | Cyclohexylphenyl carboxamides tocolytic oxytocin receptor antagonists |
US7109193B2 (en) | 2001-04-12 | 2006-09-19 | Wyeth | Tricyclic diazepines tocolytic oxytocin receptor antagonists |
US7064120B2 (en) | 2001-04-12 | 2006-06-20 | Wyeth | Tricyclic pyridyl carboxamides and derivatives thereof tocolytic oxytocin receptor antagonists |
US6977254B2 (en) | 2001-04-12 | 2005-12-20 | Wyeth | Hydroxy cyclohexenyl phenyl carboxamides tocolytic oxytocin receptor antagonists |
US6903087B2 (en) | 2001-04-12 | 2005-06-07 | Wyeth | Pyrido cyclohexenyl phenyl carboxamides tocolytic oxytocin receptor antagonists |
US7326700B2 (en) | 2001-04-12 | 2008-02-05 | Wyeth | Cyclohexenyl phenyl carboxamides tocolytic oxytocin receptor antagonists |
EP1434763B1 (fr) * | 2001-10-12 | 2018-01-17 | Azevan Pharmaceuticals, Inc. | Antagonistes v1a de vasopressine beta-lactamyl |
MXPA05011521A (es) | 2003-04-28 | 2006-01-23 | Astellas Pharma Inc | Derivado de 4,4-difluoro-1,2,3,4-tetrahidro-5h-1-benzazepina o una sal del mismo. |
GB0406917D0 (en) | 2004-03-26 | 2004-04-28 | Photocure Asa | Compounds |
MX2007002248A (es) * | 2004-08-25 | 2008-10-02 | Pfizer | Triazolobenzodiazepinas y su uso como antagonistas de vasopresina. |
AU2006227199A1 (en) | 2005-03-22 | 2006-09-28 | Azevan Pharmaceuticals, Inc. | Beta-lactamylalkanoic acids for treating premenstrual disorders |
PL2356123T3 (pl) | 2008-11-13 | 2013-03-29 | Hoffmann La Roche | Spiro-5,6-dihudro-4h-2,3,5,10b- tetraazabenzo[e]azuleny |
EP2308866A1 (fr) | 2009-10-09 | 2011-04-13 | Bayer CropScience AG | Phenylpyri(mi)dinylpyrazoles et leur utilisation comme fongicides |
US8420633B2 (en) * | 2010-03-31 | 2013-04-16 | Hoffmann-La Roche Inc. | Aryl-cyclohexyl-tetraazabenzo[e]azulenes |
GB201005623D0 (en) | 2010-04-01 | 2010-05-19 | Vantia Ltd | New polymorph |
US8461151B2 (en) * | 2010-04-13 | 2013-06-11 | Hoffmann-La Roche Inc. | Aryl-/heteroaryl-cyclohexenyl-tetraazabenzo[e]azulenes |
US8481528B2 (en) * | 2010-04-26 | 2013-07-09 | Hoffmann-La Roche Inc. | Heterobiaryl-cyclohexyl-tetraazabenzo[e]azulenes |
US8513238B2 (en) * | 2010-05-10 | 2013-08-20 | Hoffmann-La Roche Inc. | Heteroaryl-cyclohexyl-tetraazabenzo[E]azulenes |
ES2662350T3 (es) | 2010-07-01 | 2018-04-06 | Azevan Pharmaceuticals, Inc. | Procedimientos para el tratamiento del trastorno por estrés postraumático |
WO2014134391A1 (fr) | 2013-02-28 | 2014-09-04 | Bristol-Myers Squibb Company | Dérivés de phénylpyrazole en tant que puissants inhibiteurs de rock1 et rock2 |
TW201444798A (zh) | 2013-02-28 | 2014-12-01 | 必治妥美雅史谷比公司 | 作爲強效rock1及rock2抑制劑之苯基吡唑衍生物 |
SI3122743T1 (sl) | 2014-03-28 | 2023-07-31 | Azevan Pharmaceuticals, Inc. | Sestavki in metode za zdravljenje nevrodegenerativnih bolezni |
CN111295373A (zh) | 2017-09-15 | 2020-06-16 | 阿泽凡药物公司 | 用于治疗脑损伤的组合物和方法 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5516774A (en) * | 1993-07-29 | 1996-05-14 | American Cyanamid Company | Tricyclic diazepine vasopressin antagonists and oxytocin antagonists |
US5521173A (en) * | 1995-01-17 | 1996-05-28 | American Home Products Corporation | Tricyclic benzazepine vasopressin antagonists |
TW359669B (en) * | 1995-12-15 | 1999-06-01 | Otsuka Pharma Co Ltd | Benzazepine derivatives |
-
1998
- 1998-07-24 KR KR1020007000977A patent/KR100580805B1/ko not_active IP Right Cessation
- 1998-07-24 DE DE69826487T patent/DE69826487T2/de not_active Expired - Fee Related
- 1998-07-24 ES ES98938017T patent/ES2229525T3/es not_active Expired - Lifetime
- 1998-07-24 PT PT98938017T patent/PT1000062E/pt unknown
- 1998-07-24 JP JP2000505167A patent/JP4338305B2/ja not_active Expired - Fee Related
- 1998-07-24 WO PCT/US1998/015495 patent/WO1999006409A1/fr active IP Right Grant
- 1998-07-24 SI SI9830693T patent/SI1000062T1/xx unknown
- 1998-07-24 CA CA002297406A patent/CA2297406C/fr not_active Expired - Fee Related
- 1998-07-24 AT AT98938017T patent/ATE277050T1/de not_active IP Right Cessation
- 1998-07-24 RU RU2000104865/04A patent/RU2213094C2/ru not_active IP Right Cessation
- 1998-07-24 CN CNB988096412A patent/CN1183134C/zh not_active Expired - Fee Related
- 1998-07-24 DK DK98938017T patent/DK1000062T3/da active
- 1998-07-24 IL IL13378898A patent/IL133788A0/xx unknown
- 1998-07-24 HU HU0002480A patent/HUP0002480A3/hu unknown
- 1998-07-24 NZ NZ502449A patent/NZ502449A/xx unknown
- 1998-07-24 BR BR9811585-5A patent/BR9811585A/pt not_active IP Right Cessation
- 1998-07-24 EP EP98938017A patent/EP1000062B1/fr not_active Expired - Lifetime
- 1998-07-24 AU AU86633/98A patent/AU756959B2/en not_active Ceased
- 1998-07-28 TW TW087112353A patent/TW502035B/zh not_active IP Right Cessation
- 1998-07-29 ZA ZA9806784A patent/ZA986784B/xx unknown
- 1998-07-29 AR ARP980103736A patent/AR016557A1/es unknown
-
2000
- 2000-01-18 NO NO20000242A patent/NO315273B1/no unknown
Also Published As
Publication number | Publication date |
---|---|
BR9811585A (pt) | 2000-09-26 |
PT1000062E (pt) | 2004-12-31 |
ATE277050T1 (de) | 2004-10-15 |
EP1000062B1 (fr) | 2004-09-22 |
NZ502449A (en) | 2002-08-28 |
NO20000242L (no) | 2000-03-06 |
DE69826487D1 (de) | 2004-10-28 |
ZA986784B (en) | 2000-06-22 |
DK1000062T3 (da) | 2004-11-22 |
JP4338305B2 (ja) | 2009-10-07 |
CA2297406C (fr) | 2009-02-24 |
RU2213094C2 (ru) | 2003-09-27 |
CN1183134C (zh) | 2005-01-05 |
HUP0002480A3 (en) | 2002-09-30 |
NO315273B1 (no) | 2003-08-11 |
TW502035B (en) | 2002-09-11 |
KR20010022398A (ko) | 2001-03-15 |
EP1000062A1 (fr) | 2000-05-17 |
SI1000062T1 (en) | 2004-12-31 |
JP2001512125A (ja) | 2001-08-21 |
CA2297406A1 (fr) | 1999-02-11 |
AR016557A1 (es) | 2001-07-25 |
HUP0002480A2 (hu) | 2000-11-28 |
WO1999006409A1 (fr) | 1999-02-11 |
AU8663398A (en) | 1999-02-22 |
NO20000242D0 (no) | 2000-01-18 |
AU756959B2 (en) | 2003-01-30 |
CN1272111A (zh) | 2000-11-01 |
ES2229525T3 (es) | 2005-04-16 |
DE69826487T2 (de) | 2005-12-01 |
KR100580805B1 (ko) | 2006-05-17 |
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