IL139697A - Nitric oxide synthase inhibitors, pharmaceutical compositions comprising them and process for their preparation - Google Patents

Nitric oxide synthase inhibitors, pharmaceutical compositions comprising them and process for their preparation

Info

Publication number: IL139697A
Authority: IL; Israel
Prior art keywords: preparation; pharmaceutical compositions; nitric oxide; oxide synthase; synthase inhibitors
Prior art date: 1998-05-30

Application number

IL13969799A

Other languages

English (en)

Other versions

IL139697A0 (en

Original Assignee

Glaxo Group Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-05-30

Filing date

1999-05-27

Publication date

2005-12-18

1999-05-27 Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd

2002-02-10 Publication of IL139697A0 publication Critical patent/IL139697A0/xx

2005-12-18 Publication of IL139697A publication Critical patent/IL139697A/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/57—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups
- C07C323/58—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups with amino groups bound to the carbon skeleton
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Public Health (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Pulmonology (AREA)
Biomedical Technology (AREA)
Immunology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Dermatology (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Urology & Nephrology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

IL13969799A 1998-05-30 1999-05-27 Nitric oxide synthase inhibitors, pharmaceutical compositions comprising them and process for their preparation IL139697A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB9811599.1A GB9811599D0 (en)	1998-05-30	1998-05-30	Nitric oxide synthase inhibitors
PCT/EP1999/003583 WO1999062875A1 (en)	1998-05-30	1999-05-27	Nitric oxide synthase inhibitors

Publications (2)

Publication Number	Publication Date
IL139697A0 IL139697A0 (en)	2002-02-10
IL139697A true IL139697A (en)	2005-12-18

Family

ID=10832929

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL13969799A IL139697A (en)	1998-05-30	1999-05-27	Nitric oxide synthase inhibitors, pharmaceutical compositions comprising them and process for their preparation

Country Status (31)

Country	Link
US (2)	US6355689B1 (no)
EP (1)	EP1084104B1 (no)
JP (1)	JP3839256B2 (no)
KR (1)	KR20010043920A (no)
CN (1)	CN1218940C (no)
AP (1)	AP1382A (no)
AT (1)	ATE245142T1 (no)
AU (1)	AU757042B2 (no)
BR (1)	BR9910849A (no)
CA (1)	CA2333322C (no)
CZ (1)	CZ297473B6 (no)
DE (1)	DE69909625T2 (no)
DK (1)	DK1084104T3 (no)
EA (1)	EA003026B1 (no)
EE (1)	EE04149B1 (no)
ES (1)	ES2203147T3 (no)
GB (1)	GB9811599D0 (no)
HK (1)	HK1034241A1 (no)
HU (1)	HUP0102472A3 (no)
ID (1)	ID26790A (no)
IL (1)	IL139697A (no)
IS (1)	IS2442B (no)
NO (1)	NO20006044L (no)
NZ (1)	NZ508222A (no)
PL (1)	PL194784B1 (no)
PT (1)	PT1084104E (no)
RS (1)	RS49984B (no)
SK (1)	SK18052000A3 (no)
TR (1)	TR200003539T2 (no)
WO (1)	WO1999062875A1 (no)
ZA (1)	ZA200006847B (no)

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US20060247216A1 (en) *	2002-10-25	2006-11-02	Haj-Yehia Abdullah I	Steroid compounds comprising superoxide dismutase mimic groups and nitric oxide donor groups, and their use in the preparation of medicaments
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1998
- 1998-05-30 GB GBGB9811599.1A patent/GB9811599D0/en not_active Ceased
1999
- 1999-05-27 JP JP2000552087A patent/JP3839256B2/ja not_active Expired - Fee Related
- 1999-05-27 EP EP99926397A patent/EP1084104B1/en not_active Expired - Lifetime
- 1999-05-27 DK DK99926397T patent/DK1084104T3/da active
- 1999-05-27 US US09/701,473 patent/US6355689B1/en not_active Expired - Lifetime
- 1999-05-27 AU AU43671/99A patent/AU757042B2/en not_active Ceased
- 1999-05-27 WO PCT/EP1999/003583 patent/WO1999062875A1/en active IP Right Grant
- 1999-05-27 CZ CZ20004450A patent/CZ297473B6/cs not_active IP Right Cessation
- 1999-05-27 IL IL13969799A patent/IL139697A/xx not_active IP Right Cessation
- 1999-05-27 TR TR2000/03539T patent/TR200003539T2/xx unknown
- 1999-05-27 CN CNB998068578A patent/CN1218940C/zh not_active Expired - Fee Related
- 1999-05-27 KR KR1020007013451A patent/KR20010043920A/ko not_active Application Discontinuation
- 1999-05-27 NZ NZ508222A patent/NZ508222A/xx unknown
- 1999-05-27 ID IDW20002495A patent/ID26790A/id unknown
- 1999-05-27 HU HU0102472A patent/HUP0102472A3/hu unknown
- 1999-05-27 CA CA002333322A patent/CA2333322C/en not_active Expired - Fee Related
- 1999-05-27 BR BR9910849-6A patent/BR9910849A/pt not_active Application Discontinuation
- 1999-05-27 RS YUP-746/00A patent/RS49984B/sr unknown
- 1999-05-27 PL PL344368A patent/PL194784B1/pl unknown
- 1999-05-27 EE EEP200000716A patent/EE04149B1/xx not_active IP Right Cessation
- 1999-05-27 AT AT99926397T patent/ATE245142T1/de not_active IP Right Cessation
- 1999-05-27 DE DE69909625T patent/DE69909625T2/de not_active Expired - Lifetime
- 1999-05-27 AP APAP/P/2000/001998A patent/AP1382A/en active
- 1999-05-27 EA EA200001122A patent/EA003026B1/ru not_active IP Right Cessation
- 1999-05-27 PT PT99926397T patent/PT1084104E/pt unknown
- 1999-05-27 SK SK1805-2000A patent/SK18052000A3/sk unknown
- 1999-05-27 ES ES99926397T patent/ES2203147T3/es not_active Expired - Lifetime
2000
- 2000-11-21 IS IS5723A patent/IS2442B/is unknown
- 2000-11-22 ZA ZA200006847A patent/ZA200006847B/en unknown
- 2000-11-29 NO NO20006044A patent/NO20006044L/no not_active Application Discontinuation
2001
- 2001-07-07 HK HK01104682A patent/HK1034241A1/xx unknown
- 2001-11-26 US US09/994,969 patent/US6495606B1/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
PL344368A1 (en)	2001-11-05
HUP0102472A3 (en)	2002-12-28
EA003026B1 (ru)	2002-12-26
EE04149B1 (et)	2003-10-15
GB9811599D0 (en)	1998-07-29
EP1084104A1 (en)	2001-03-21
CZ20004450A3 (en)	2001-05-16
NO20006044L (no)	2001-01-29
YU74600A (sh)	2002-12-10
JP3839256B2 (ja)	2006-11-01
ID26790A (id)	2001-02-08
DK1084104T3 (da)	2003-10-27
HUP0102472A2 (hu)	2002-03-28
IS5723A (is)	2000-11-21
AU4367199A (en)	1999-12-20
IS2442B (is)	2008-11-15
SK18052000A3 (sk)	2001-06-11
ES2203147T3 (es)	2004-04-01
WO1999062875A1 (en)	1999-12-09
CA2333322A1 (en)	1999-12-09
ATE245142T1 (de)	2003-08-15
CN1303367A (zh)	2001-07-11
AU757042B2 (en)	2003-01-30
CN1218940C (zh)	2005-09-14
US6495606B1 (en)	2002-12-17
RS49984B (sr)	2008-09-29
JP2002516901A (ja)	2002-06-11
IL139697A0 (en)	2002-02-10
DE69909625D1 (en)	2003-08-21
NO20006044D0 (no)	2000-11-29
CA2333322C (en)	2008-01-22
PT1084104E (pt)	2003-11-28
ZA200006847B (en)	2001-11-22
KR20010043920A (ko)	2001-05-25
CZ297473B6 (cs)	2006-12-13
AP1382A (en)	2005-04-01
AP2000001998A0 (en)	2000-12-31
EP1084104B1 (en)	2003-07-16
TR200003539T2 (tr)	2001-06-21
NZ508222A (en)	2003-02-28
DE69909625T2 (de)	2004-06-24
HK1034241A1 (en)	2001-10-19
PL194784B1 (pl)	2007-07-31
US6355689B1 (en)	2002-03-12
EE200000716A (et)	2002-04-15
EA200001122A1 (ru)	2001-06-25
BR9910849A (pt)	2001-02-20

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Legal Events

Date	Code	Title	Description
2006-07-05	FF	Patent granted
2010-10-31	MM9K	Patent not in force due to non-payment of renewal fees