[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

IL126593A0 - Process for preparing benzoic acid derivative intermediates - Google Patents

Process for preparing benzoic acid derivative intermediates

Info

Publication number
IL126593A0
IL126593A0 IL12659398A IL12659398A IL126593A0 IL 126593 A0 IL126593 A0 IL 126593A0 IL 12659398 A IL12659398 A IL 12659398A IL 12659398 A IL12659398 A IL 12659398A IL 126593 A0 IL126593 A0 IL 126593A0
Authority
IL
Israel
Prior art keywords
compound
formula
product
chem
alkyl
Prior art date
Application number
IL12659398A
Other languages
English (en)
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of IL126593A0 publication Critical patent/IL126593A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/38—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to acyclic carbon atoms and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/56—Radicals substituted by oxygen atoms
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrrole Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Steroid Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
IL12659398A 1994-08-31 1995-08-28 Process for preparing benzoic acid derivative intermediates IL126593A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/298,891 US5731436A (en) 1994-08-31 1994-08-31 Process for preparing benzoic acid derivative intermediates and benzothiophene pharmaceutical agents
IL11509195A IL115091A (en) 1994-08-31 1995-08-28 Process for preparing benzothiophene pharmaceutical agents

Publications (1)

Publication Number Publication Date
IL126593A0 true IL126593A0 (en) 1999-08-17

Family

ID=23152424

Family Applications (3)

Application Number Title Priority Date Filing Date
IL12659395A IL126593A (en) 1994-08-31 1995-08-28 Process for preparing benzoic acid derivative intermediates
IL11509195A IL115091A (en) 1994-08-31 1995-08-28 Process for preparing benzothiophene pharmaceutical agents
IL12659398A IL126593A0 (en) 1994-08-31 1995-08-28 Process for preparing benzoic acid derivative intermediates

Family Applications Before (2)

Application Number Title Priority Date Filing Date
IL12659395A IL126593A (en) 1994-08-31 1995-08-28 Process for preparing benzoic acid derivative intermediates
IL11509195A IL115091A (en) 1994-08-31 1995-08-28 Process for preparing benzothiophene pharmaceutical agents

Country Status (15)

Country Link
US (2) US5731436A (xx)
EP (1) EP0699673B1 (xx)
JP (1) JPH08119912A (xx)
KR (1) KR960007544A (xx)
AT (1) ATE165356T1 (xx)
BR (1) BR9503847A (xx)
CA (1) CA2157235A1 (xx)
DE (1) DE69502153T2 (xx)
DK (1) DK0699673T3 (xx)
ES (1) ES2114722T3 (xx)
FI (1) FI954068A (xx)
GR (1) GR3026743T3 (xx)
HU (1) HUT73136A (xx)
IL (3) IL126593A (xx)
TW (1) TW368497B (xx)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6515009B1 (en) 1991-09-27 2003-02-04 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US5811447A (en) 1993-01-28 1998-09-22 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US6251920B1 (en) 1993-05-13 2001-06-26 Neorx Corporation Prevention and treatment of cardiovascular pathologies
US6491938B2 (en) 1993-05-13 2002-12-10 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US5731436A (en) * 1994-08-31 1998-03-24 Eli Lilly And Company Process for preparing benzoic acid derivative intermediates and benzothiophene pharmaceutical agents
CA2213810C (en) * 1996-08-29 2006-06-06 Lewis Dale Pennington Benzo¬b|thiophene compounds, intermediates, processes, compositions and methods
US5948796A (en) * 1996-10-10 1999-09-07 Eli Lilly And Company Benzo B!thiophene compounds, intermediates, formulations, and methods
WO1998046588A2 (en) 1997-04-11 1998-10-22 Neorx Corporation Compounds and therapies for the prevention of vascular and non-vascular pathologies
US6017914A (en) * 1997-09-03 2000-01-25 Eli Lilly And Company Benzo[b]thiophene compounds, intermediates, formulations, and methods
FR2817865B1 (fr) * 2000-12-11 2005-02-18 Sanofi Synthelabo Derive aminoalkoxybenzoyle sous forme de sel, son procede de preparation et son utilisation comme intermediaire de synthese
EP1832582A1 (en) 2002-09-30 2007-09-12 A/S GEA Farmaceutisk Fabrik Novel raloxifene malonic acid addition salts and/or solvates thereof, and pharmaceutical compositions comprising these
JP5603019B2 (ja) * 2008-03-26 2014-10-08 帝人株式会社 植物由来成分を有するポリエステルおよびその製造方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3864501A (en) * 1973-10-10 1975-02-04 Us Agriculture Method of enhancing coloration of fruits and vegetables with a dialhylamino-alkoxybenzene
US4133814A (en) * 1975-10-28 1979-01-09 Eli Lilly And Company 2-Phenyl-3-aroylbenzothiophenes useful as antifertility agents
IL65379A0 (en) * 1981-04-03 1982-05-31 Lilly Co Eli Process for preparing acylated benzothiophenes
US4418068A (en) * 1981-04-03 1983-11-29 Eli Lilly And Company Antiestrogenic and antiandrugenic benzothiophenes
US4380635A (en) * 1981-04-03 1983-04-19 Eli Lilly And Company Synthesis of acylated benzothiophenes
EP0394440B1 (en) * 1987-10-20 1994-05-11 Otsuka Pharmaceutical Co., Ltd. Phenylcarboxylic acid derivatives
JPH02101048A (ja) * 1988-10-07 1990-04-12 Fuji Photo Film Co Ltd サリチル酸誘導体の製造方法
US5731436A (en) * 1994-08-31 1998-03-24 Eli Lilly And Company Process for preparing benzoic acid derivative intermediates and benzothiophene pharmaceutical agents

Also Published As

Publication number Publication date
FI954068A0 (fi) 1995-08-30
IL115091A (en) 2000-08-31
JPH08119912A (ja) 1996-05-14
EP0699673A1 (en) 1996-03-06
EP0699673B1 (en) 1998-04-22
ES2114722T3 (es) 1998-06-01
HUT73136A (en) 1996-06-28
TW368497B (en) 1999-09-01
KR960007544A (ko) 1996-03-22
HU9502539D0 (en) 1995-10-30
FI954068A (fi) 1996-03-01
US5731436A (en) 1998-03-24
BR9503847A (pt) 1996-09-17
US5955608A (en) 1999-09-21
CA2157235A1 (en) 1996-03-01
IL126593A (en) 2000-08-31
ATE165356T1 (de) 1998-05-15
DE69502153D1 (de) 1998-05-28
GR3026743T3 (en) 1998-07-31
DE69502153T2 (de) 1998-09-17
DK0699673T3 (da) 1998-10-07
IL115091A0 (en) 1995-12-08

Similar Documents

Publication Publication Date Title
IL126593A0 (en) Process for preparing benzoic acid derivative intermediates
HU0003473D0 (xx)
HU209788B (en) Process for preparing n-alkyl-carbamides
HU209723B (en) Process for producing of piperazine derivatives
US4217366A (en) Pharmaceutically active 2-(4-aminobutoxy)stilbenes
US4145426A (en) Anti-microbial piperidino butan-2-ones
US5268470A (en) Diamine compounds, method of making same, method of use of same and intermediates
US4134889A (en) Manufacture of glycinonitriles
AU737994B2 (en) Process for preparing o-(3-amino-2-hydroxy-propyl)-hydroxymic acid halides
US4256666A (en) Preparation of β-aminopropionamides
Reddy et al. Unique zeolite-catalyzed synthesis of nitroketene S, N-acetals
HU219493B (hu) Alkil-trazodon-származékok előállítására alkalmazható piperazinszármazékok és eljárás előállításukra
US5118682A (en) P-hydroxy phenone derivatives and the use thereof
GB2135994A (en) Process for the preparation of basic oxime ethers
HU189227B (en) Process for preparing basic oxime-ethers
US3095425A (en) Alkanoylthiaxanthenes and-xanthenes
US6118006A (en) Method for preparing a tetrahydropyridin derivative
EP0170583B1 (fr) Sels d'ammonium dérivés de hexahydrodibenzodioxane, leurs intermédiaires, leur préparation et leur application en thérapeutique
US5922874A (en) Process for preparing N-aryl-N'-alkyl-piperazines
EP0080721A2 (en) Diphenylalkanoamine derivatives, and their production and use
SU1318593A1 (ru) Способ получени алкилпроизводных хинолина
WO2001032641A1 (en) Process for preparing piperazine-substituted aliphatic carboxylates
NO167974B (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive aminopropanolderivater av 3-(2-hydroksyfenyl)-1-propanonforbindelser.