[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

IE41145L - Pyroglutamyl compounds - Google Patents

Pyroglutamyl compounds

Info

Publication number
IE41145L
IE41145L IE751069A IE106975A IE41145L IE 41145 L IE41145 L IE 41145L IE 751069 A IE751069 A IE 751069A IE 106975 A IE106975 A IE 106975A IE 41145 L IE41145 L IE 41145L
Authority
IE
Ireland
Prior art keywords
compounds
group
pyroglutamyl
carbon atoms
branched alkyl
Prior art date
Application number
IE751069A
Other languages
Unknown language ( )
Other versions
IE41145B1 (en
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of IE41145L publication Critical patent/IE41145L/en
Publication of IE41145B1 publication Critical patent/IE41145B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • C07D207/277—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D207/28—2-Pyrrolidone-5- carboxylic acids; Functional derivatives thereof, e.g. esters, nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06139—Dipeptides with the first amino acid being heterocyclic
    • C07K5/06173—Dipeptides with the first amino acid being heterocyclic and Glp-amino acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Novel pyroglutamyl compounds of the formula I <IMAGE> in which X denotes an optionally branched alkyl radical having 2 to 6 carbon atoms or an optionally branched alkyl radical having 2 to 6 carbon atoms which is either substituted in the alpha -position by a carbamoyl group or in the omega -position by a carbamoyl group or a carboxyl group, are prepared by reaction of a pyroglutamic acid, which is optionally substituted on the nitrogen by a benzyloxycarbonyl radical, or of a reactive derivative thereof with a primary amine which introduces the group X and subsequent removal of possible carboxyl protective groups. The novel compounds are useful therapeutics for the treatment of psychic disorders, in particular of depressions.
IE1069/75A 1974-05-14 1975-05-13 Pyroglutamyl compounds and process for their manufacture IE41145B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2423390A DE2423390A1 (en) 1974-05-14 1974-05-14 PYROGLUTAMYL COMPOUNDS WITH ANTIDEPRESSIVE EFFECT AND PROCESS FOR THEIR PRODUCTION

Publications (2)

Publication Number Publication Date
IE41145L true IE41145L (en) 1975-11-14
IE41145B1 IE41145B1 (en) 1979-10-24

Family

ID=5915523

Family Applications (1)

Application Number Title Priority Date Filing Date
IE1069/75A IE41145B1 (en) 1974-05-14 1975-05-13 Pyroglutamyl compounds and process for their manufacture

Country Status (14)

Country Link
JP (1) JPS50157362A (en)
AT (2) AT352707B (en)
BE (1) BE829059A (en)
CA (1) CA1064942A (en)
CH (2) CH613689A5 (en)
DE (1) DE2423390A1 (en)
DK (1) DK209575A (en)
FR (1) FR2270866B1 (en)
GB (1) GB1472154A (en)
IE (1) IE41145B1 (en)
IL (1) IL47258A (en)
LU (1) LU72450A1 (en)
NL (1) NL7505473A (en)
SE (1) SE405113B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3184395A (en) * 1994-08-05 1996-03-04 Warwick International Group Limited Bleach activators
EP1024134A4 (en) * 1997-10-09 2003-05-14 Ono Pharmaceutical Co Aminobutanoic acid derivatives
RU2232578C1 (en) * 2003-04-10 2004-07-20 Ахапкина Валентина Ивановна Substance eliciting antidepressant activity

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5220996B2 (en) * 1972-01-14 1977-06-07
JPS5015793B2 (en) * 1972-06-07 1975-06-07

Also Published As

Publication number Publication date
LU72450A1 (en) 1977-02-09
AT352707B (en) 1979-10-10
CA1064942A (en) 1979-10-23
DE2423390A1 (en) 1975-12-04
SE405113B (en) 1978-11-20
BE829059A (en) 1975-11-14
DK209575A (en) 1975-11-15
IE41145B1 (en) 1979-10-24
JPS50157362A (en) 1975-12-19
CH612180A5 (en) 1979-07-13
GB1472154A (en) 1977-05-04
ATA364875A (en) 1979-03-15
SE7505546L (en) 1975-11-17
ATA13179A (en) 1981-04-15
FR2270866A1 (en) 1975-12-12
FR2270866B1 (en) 1978-08-04
NL7505473A (en) 1975-11-18
CH613689A5 (en) 1979-10-15
IL47258A0 (en) 1975-07-28
AT364875B (en) 1979-03-15
IL47258A (en) 1978-07-31

Similar Documents

Publication Publication Date Title
IE790210L (en) Alkylenediamine derivatives
ATE20051T1 (en) AMIDE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND ANTICOMPLEMENT AGENTS CONTAINING THEM.
ES8308869A1 (en) Cyclic carbonic acid derivatives, process for their preparation and their use as copolymerisation constituents for the preparation of polycarbonates.
PT76316A (en) Process for the preparation of esters of substituted pyridino- 3,5-dicarboxylic and/or of pyrano-3,5-dicarboxylic acids having an hypotensive effect and application thereof for the preparation of pharmaceutical compositions having an hypotensive effect
IE801342L (en) Peptides
JPS574953A (en) Preparation of peptide amide sulfate ester terminated with cholecystokinin-pancreozymin c
IE40945B1 (en) Benzomorphanes derivatives
JPS5223001A (en) Process for elimination of formyl group
GB1507774A (en) Photosensitive element and composition for producing photoresists
ES444948A1 (en) Pure potassium salt of clavulanic acid
ES489823A1 (en) Catalyst, its preparation and process for polymerizing butadiene.
IE41145L (en) Pyroglutamyl compounds
GB1491840A (en) Derivatives of copolymers of carbon monoxide and ethylene
ES470296A1 (en) Fluorinated amino acids
GB1496692A (en) Process for the preparation of ceph-2-em compounds
IE40883L (en) Amidoxime pharmaceuticals
ES447495A1 (en) 4,5,6,7-Tetrahydro-thieno{8 3,2-c{9 -pyridine derivatives and process for their preparation
ES463682A1 (en) Derivatives of coenzyme B12
ES8607972A1 (en) Hetereocyclic compounds, process for their preparation, pharmaceutical compositions containing them and their use.
IE39576B1 (en) Derivatives of 3-(p-chlorobenzoyl)-2-methyl-phenylacetic acid
ES457563A1 (en) Dipeptide derivatives
ES8100282A1 (en) Piperazine methane imine derivatives, methods for their preparation and their therapeutical use.
ES441126A1 (en) Pharmaceutically useful prostenoic acid derivatives
ES461983A1 (en) Cephalosporins
ES481486A1 (en) 1-Pyrrole- and 1-pyrrolidine-carboxylic acid derivatives and process for preparing the same