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HUT61278A - Process for separating and cleaning 1-methyl-2-pyrrolidinyl ethanol enanthiomers - Google Patents

Process for separating and cleaning 1-methyl-2-pyrrolidinyl ethanol enanthiomers

Info

Publication number
HUT61278A
HUT61278A HU186091A HU186091A HUT61278A HU T61278 A HUT61278 A HU T61278A HU 186091 A HU186091 A HU 186091A HU 186091 A HU186091 A HU 186091A HU T61278 A HUT61278 A HU T61278A
Authority
HU
Hungary
Prior art keywords
methyl
enanthiomers
separating
cleaning
pyrrolidinyl
Prior art date
Application number
HU186091A
Other languages
Hungarian (hu)
Other versions
HU208670B (en
HU911860D0 (en
Inventor
Maria Acs
Elemer Fogassy
Timea Szili
Original Assignee
Budapesti Mueszaki Egyetem
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Budapesti Mueszaki Egyetem filed Critical Budapesti Mueszaki Egyetem
Priority to HU186091A priority Critical patent/HU208670B/en
Publication of HU911860D0 publication Critical patent/HU911860D0/en
Publication of HUT61278A publication Critical patent/HUT61278A/en
Publication of HU208670B publication Critical patent/HU208670B/en

Links

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  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrrole Compounds (AREA)

Abstract

1-methyl-2-pyrrolidinyl-ethanol enantiomers are sepd. and purified by application of (-)-di:p-toluyl-tartaric acid. Diastereomers are isolated from the reaction mixt. to and the diastereomer salts are decomposed. Enantiomers are extracted and are obtd. following prior concn.
HU186091A 1991-06-04 1991-06-04 Process for separating and clean ing 1-methyl-2-pyrrolidinyl ethanol enenthiomers HU208670B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
HU186091A HU208670B (en) 1991-06-04 1991-06-04 Process for separating and clean ing 1-methyl-2-pyrrolidinyl ethanol enenthiomers

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU186091A HU208670B (en) 1991-06-04 1991-06-04 Process for separating and clean ing 1-methyl-2-pyrrolidinyl ethanol enenthiomers

Publications (3)

Publication Number Publication Date
HU911860D0 HU911860D0 (en) 1991-12-30
HUT61278A true HUT61278A (en) 1992-12-28
HU208670B HU208670B (en) 1993-12-28

Family

ID=10956562

Family Applications (1)

Application Number Title Priority Date Filing Date
HU186091A HU208670B (en) 1991-06-04 1991-06-04 Process for separating and clean ing 1-methyl-2-pyrrolidinyl ethanol enenthiomers

Country Status (1)

Country Link
HU (1) HU208670B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103387528B (en) * 2013-08-01 2014-09-10 刘怀振 Resolution method of N-methyl-2(2-hydroxyethyl)pyrrolidine and application thereof
CN111087337A (en) * 2019-11-19 2020-05-01 山东科源制药股份有限公司 Method for splitting chloromalastine fumarate intermediate
CN111302996A (en) * 2020-03-19 2020-06-19 山东科源制药股份有限公司 Preparation method of high-chiral-purity chloromalastine fumarate

Also Published As

Publication number Publication date
HU208670B (en) 1993-12-28
HU911860D0 (en) 1991-12-30

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Legal Events

Date Code Title Description
HMM4 Cancellation of final prot. due to non-payment of fee