HUP9900601A2 - Benzopirán-származékok allograftkilökődés megelőzésére - Google Patents
Benzopirán-származékok allograftkilökődés megelőzéséreInfo
- Publication number
- HUP9900601A2 HUP9900601A2 HU9900601A HUP9900601A HUP9900601A2 HU P9900601 A2 HUP9900601 A2 HU P9900601A2 HU 9900601 A HU9900601 A HU 9900601A HU P9900601 A HUP9900601 A HU P9900601A HU P9900601 A2 HUP9900601 A2 HU P9900601A2
- Authority
- HU
- Hungary
- Prior art keywords
- derivatives
- benzopirane
- allograft rejection
- prevention
- mammals
- Prior art date
Links
- 230000002265 prevention Effects 0.000 title 1
- 241000124008 Mammalia Species 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 229930105110 Cyclosporin A Natural products 0.000 abstract 1
- PMATZTZNYRCHOR-CGLBZJNRSA-N Cyclosporin A Chemical compound CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O PMATZTZNYRCHOR-CGLBZJNRSA-N 0.000 abstract 1
- 108010036949 Cyclosporine Proteins 0.000 abstract 1
- 230000000735 allogeneic effect Effects 0.000 abstract 1
- 150000001562 benzopyrans Chemical class 0.000 abstract 1
- 229960001265 ciclosporin Drugs 0.000 abstract 1
- 238000002648 combination therapy Methods 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Transplantation (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pyrane Compounds (AREA)
Abstract
A találmány tárgya benzopiránszármazékok alkalmazása allogéntranszplantátumok elutasításának elfojtására emlősökben és emberekben,amely alkalmazás abból áll, hogy az említett emlősöknek vagyembereknek valamely (I) általános képletű vegyületnek, amelyben n, A,B, R1 és R2 jelentése a leírásban meghatározott, vagy gyógyászatilagelfogadható sójának gyógyászatilag hatásos mennyiségét adják bekombinált terápiában ciklosporin A-val vagy FK506-tal együtt. Ó
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US7769998P | 1998-03-12 | 1998-03-12 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HU9900601D0 HU9900601D0 (en) | 1999-05-28 |
| HUP9900601A2 true HUP9900601A2 (hu) | 2001-04-28 |
Family
ID=22139565
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU9900601A HUP9900601A2 (hu) | 1998-03-12 | 1999-03-11 | Benzopirán-származékok allograftkilökődés megelőzésére |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP0943339A3 (hu) |
| JP (1) | JPH11322599A (hu) |
| KR (1) | KR19990077751A (hu) |
| AU (1) | AU2038899A (hu) |
| CA (1) | CA2265209A1 (hu) |
| HU (1) | HUP9900601A2 (hu) |
| IL (1) | IL128731A0 (hu) |
| ZA (1) | ZA991978B (hu) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0963755A3 (en) * | 1998-04-16 | 2001-03-14 | Pfizer Products Inc. | Use of benzopyranes for preventing allograft rejection |
| CR20170420A (es) | 2015-03-13 | 2017-10-03 | Forma Therapeutics Inc | Compuestos y composiciones de alfa-cinamida como inhibidores de hdac8 |
| WO2017040963A1 (en) | 2015-09-03 | 2017-03-09 | Forma Therapeutics, Inc. | [6,6] fused bicyclic hdac8 inhibitors |
| US20190382363A1 (en) * | 2015-11-30 | 2019-12-19 | Merck Sharp & Dohme Corp. | Aryl sulfonamides as blt1 antagonists |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU7198794A (en) * | 1994-03-18 | 1995-10-09 | Smithkline Beecham Corporation | Treating cyclosporine-induced nephrotoxicity |
| AU696890B2 (en) * | 1994-10-13 | 1998-09-24 | Pfizer Inc. | Benzopyran and benzo-fused compounds, their preparation and their use as leukotriene B4 (LTB4) antagonists |
-
1999
- 1999-02-25 IL IL12873199A patent/IL128731A0/xx unknown
- 1999-03-10 KR KR1019990007925A patent/KR19990077751A/ko not_active Application Discontinuation
- 1999-03-10 CA CA002265209A patent/CA2265209A1/en not_active Abandoned
- 1999-03-11 AU AU20388/99A patent/AU2038899A/en not_active Abandoned
- 1999-03-11 EP EP99301870A patent/EP0943339A3/en not_active Withdrawn
- 1999-03-11 ZA ZA9901978A patent/ZA991978B/xx unknown
- 1999-03-11 HU HU9900601A patent/HUP9900601A2/hu unknown
- 1999-03-12 JP JP11066202A patent/JPH11322599A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP0943339A2 (en) | 1999-09-22 |
| KR19990077751A (ko) | 1999-10-25 |
| EP0943339A3 (en) | 2001-11-07 |
| IL128731A0 (en) | 2000-01-31 |
| ZA991978B (en) | 2000-10-11 |
| AU2038899A (en) | 1999-09-23 |
| HU9900601D0 (en) | 1999-05-28 |
| CA2265209A1 (en) | 1999-09-12 |
| JPH11322599A (ja) | 1999-11-24 |
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